Major interaction on record — check this product against your medications before combining. Based on 5 of 6 ingredients. Check your meds →
Dietary supplement

SeroVital Ingredients & Drug Interactions

by SanMedica International

SeroVital label
See full label image
Capsule Category: Amino Acid/protein
Most serious interaction: Major
Clinical methodology reviewed by · Updated Sep 16, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking SeroVital against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Major

SeroVital is a dietary supplement by SanMedica International with 6 active ingredients. Its ingredients are commonly taken for muscle recovery and sports performance, gut health and 'leaky gut', recovery from severe illness or injury.Based on those ingredients, 1,132 medications have a known interaction with it, the most serious rated major. The ingredients most likely to interact are Schizonepeta powder, L-Arginine Hydrochloride, N-Acetyl L-Cysteine. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

Jump to a section

Check Your Meds Against SeroVital by SanMedica International

Ask about any prescription or over-the-counter medication and we check it for interactions with SeroVital by SanMedica International — and tell you which ingredient is responsible.

Pharmacist-reviewed data Checks every ingredient Answer in seconds
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HelloPharmacist Scorecard of SeroVital by SanMedica International

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Jul 11, 2026

What’s inside

Low disclosure
Ingredient Transparency · database check
Low

Most active ingredients don't disclose an individual amount — you can't tell how much of each you're getting.

Why this rating?
  • The label discloses an exact amount for 0 of its 6 active ingredients.
  • “Amino Renewal Complex” is a proprietary blend — the label gives one combined amount (2.90 Gram(s)) without saying how much of each component you get.

SeroVital contains six active ingredients. The amino acids L-glutamine, L-lysine hydrochloride, N-acetyl L-cysteine (NAC), and L-arginine hydrochloride are included alongside oxo-proline and schizonepeta powder.

An "Amino Renewal Complex" listed as an ingredient refers to the component amino acids already named individually. The capsules also contain several inactive ingredients — fillers and binders like magnesium stearate, microcrystalline cellulose, rice flour, and gelatin, plus colorants and other excipients.

Does it work?

Not established
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not established

The graded evidence we hold for these ingredients covers different conditions than the ones this product is marketed for, so there's no established rating for its stated use.

Why this rating?
  • The label markets this product for: naturally increase human growth hormone and sleep quality.
  • We looked for evidence on: Aging, Athletic performance, Child growth, Chronic fatigue syndrome (CFS), Exercise-induced muscle damage, Male infertility — and 4 related terms.
  • The closest evidence on file: Glutamine is rated "Possibly Ineffective" for Athletic performance (Natural Medicines).
  • Also on file: Lysine is rated "Insufficient Reliable Evidence To Rate" for Athletic performance, Muscle strength, Child growth.
  • Also on file: Glutamine is rated "Insufficient Reliable Evidence To Rate" for Exercise-induced muscle damage.

The evidence for SeroVital's active ingredients is mixed. L-glutamine is rated Effective for sickle cell disease and Possibly Effective for HIV/AIDS-related wasting, postoperative recovery, and critical illness from trauma.

L-lysine is Possibly Effective for cold sores but has Insufficient Evidence for child growth, pressure ulcers, and diabetic foot ulcers. NAC is Effective for acetaminophen poisoning, atelectasis (collapsed lung tissue), and use in bronchial studies and tracheostomy care, and Possibly Effective for bronchitis.

We hold no effectiveness ratings for L-arginine, oxo-proline, or schizonepeta in our data.

The evidence, ingredient by ingredient Glutamine Lysine N-acetyl Cysteine (nac) L-arginine Schizonepeta

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 5 of the 5 matched ingredients.
  • Pregnancy & breastfeeding safety ratings cover 5 of 5.
  • General safety write-ups exist for 5 of 5.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

L-glutamine and L-lysine are generally well tolerated orally. Glutamine's most common side effects include belching, bloating, constipation, diarrhea, flatulence, stomach pain, headache, muscle pain, nausea, and vomiting.

Lysine commonly causes stomach pain, diarrhea, and indigestion. One rare case of kidney injury (tubulointerstitial nephritis progressing to chronic renal failure) was reported with long-term lysine use.

NAC is generally well tolerated at typical doses; common side effects are diarrhea, dry mouth, indigestion, heartburn, loss of appetite, nausea, and vomiting. L-arginine is generally well tolerated short-term and may cause stomach pain, bloating, nausea, diarrhea, headache, insomnia, or flushing.

People with kidney or liver disease should use glutamine only under medical supervision. Schizonepeta is used traditionally in small amounts, but high-quality safety data in humans is limited; high doses may be toxic to the liver.

For pregnancy and lactation: L-glutamine is rated Likely Safe. L-lysine, NAC, L-arginine, and schizonepeta have no sufficient safety data — pregnancy use is not well studied, and schizonepeta is advised against in pregnancy and breastfeeding.

Talk with your doctor or pharmacist about whether this product is right for you.

Side effects, ingredient by ingredient Glutamine Lysine N-acetyl Cysteine (nac) L-arginine Schizonepeta

Meds to double-check

Major interaction found
Known Interaction Concern · database check
Major identified

At least one ingredient has a documented Major-severity interaction. Check your medications for a personalized result.

Why this rating?
  • 5 of the 5 matched ingredients can interact with medications — Lysine, L-arginine, Glutamine, N-acetyl Cysteine (nac), Schizonepeta.
  • The most serious interaction on file is rated Major.
  • Some involve high-stakes drug classes: anticoagulant / antiplatelet drugs; seizure medications; diabetes medications.
  • For scale: 1,133 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Check your medications against SeroVital if you take nitroglycerin (Major risk of severe low blood pressure and headaches). Also double-check if you use blood thinners or antiplatelet drugs, blood pressure medications (including ACE inhibitors and ARBs), potassium-sparing diuretics, diabetes drugs, seizure medications (anticonvulsants), chloroquine, sildenafil (Viagra), isoproterenol, any medication processed by your liver (especially those using CYP2D6, CYP1A2, CYP3A4, or CYP2E1), or activated charcoal.

All of these carry documented Moderate or Major interactions.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFormula with limited ingredient disclosure with no established evidence rating for its marketed use. Major medication interactions have been identified, and safety information is well characterized.

SeroVital may help with sickle cell disease (glutamine) or cold sores (lysine) if those are your concerns, though evidence for other uses in this formula is limited or absent. If you take nitroglycerin, blood thinners, blood pressure medications, diabetes drugs, or any medication processed by your liver, you need to check this product against your exact medications before starting — the interaction risks are real.

Talk with your pharmacist or doctor; they can run it through a checker to see if it's safe for your specific situation.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 5 of 6 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Jun 24, 2020.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about SeroVital, straight from the product label.

Brand SanMedica International
Barcode (UPC) 681168605025
Net contents 120 Capsule(s)
Market status On market
Date entered into DSLD Jun 24, 2020
DSLD ID 228324
Product type Amino Acid/protein
Supplement form Capsule
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years)
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for SeroVital by SanMedica International, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
4 Capsule(s)
Maximum serving Sizes:
4 Capsule(s)
Servings per container
30
UPC/BARCODE
681168605025
IngredientAmount% DV
L-Glutamine0 NP--
L-Lysine Hydrochloride0 NP--
N-Acetyl L-Cysteine0 NP--
L-Arginine Hydrochloride0 NP--
Oxo-Proline0 NP--
Schizonepeta powder0 NP--
Amino Renewal Complex2.9 Gram(s)--

Other ingredients: Gelatin, Magnesium Stearate, Stearic Acid, Silicon Dioxide, Titanium Dioxide, Rice Flour, Microcrystalline Cellulose, Candurin Silver Fine, Riboflavin, FD&C Yellow No. 5, FD&C Yellow No. 6

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Formulation

SeroVital is clinically validated to naturally increase human growth hormone levels and improve sleep quality - both of which decline with age.

SeroVital is America's #1 anti-aging therapy. The strength of science. The power of youth. Reverse the signs of aging Clinically tested to increase human growth hormone Human growth hormone (HGH) is associated with Increased energy Decreased body fat Reduced fine lines & wrinkles Deeper, more restorative sleep

Clinically validated backed by 15 patents

hGH has been associated with initiating a cascade of beneficial effects throughout the body, such as strengthening the underlying substructure of your skin, stimulating collagen production, causing your fat cells to shrink, and more. SeroVital's amino renewal complex is clinically validated and is a safe and natural way to increase your hGH to more youthful levels. Experts believe hGH helps reduce fine lines and wrinkles, boost mental acuity, decrease body fat, promote deeper, more restorative sleep, and increase energy.

A Sanmedica International Formulation

General Statements

Get all the facts at SeroVital.com If you or your health-care provider have any questions, please call: 1-800-898-5153. For additional information on this or other SanMedica International products, please call our experienced customer service representatives at: 1-800-898-5153. Product resale allowed only through authorized representatives. International distribution is not authorized without prior written approval.

Individual results will vary.

Storage

Store at controlled room temperature: 15 degrees to 30 degrees C/ 59 degrees to 86 degrees F

Brand IP Statement(s)

Protected by U.S. Patent Numbers 8,551,542; 8,715,752; 8,722,114; 8,734,864; 8,747,921; 8,747,922, 8,765,195; 8,808,763; 8,808,764; 8,815,311; 9,066,953; 9,196,889; 9,238,023; 9,339,490; and Canadian Patent Number: 2840809. 2018 All rights reserved.

FDA Statement of Identity

Dietary Supplement

Suggested/Recommended/Usage/Directions

Directions: Adults take 4 capsules with water on an empty stomach, either in the morning two hours before breakfast or two hours after dinner prior to bedtime. [Do not eat or drink anything except water two hours before or after taking Serovital.] Do not exceed 4 capsules in any 24-hour period.

Precautions

[Do not eat or drink anything except water two hours before or after taking Serovital.] Do not exceed 4 capsules in any 24-hour period.

Warning: Do not exceed suggested daily serving.

Not for use by individuals under the age of 18 years.

Consult your physician before use if you are pregnant, nursing, taking medication, or have a medical condition.

Do not use if packet is torn or broken. Use only as directed.

Keep out of reach of children.

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

SeroVital by SanMedica International label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

SeroVital label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in SeroVital by SanMedica International

These are the 6 active ingredients this product is made of. Select any to open its full monograph.

Serving size4 Capsule(s) Dosage formCapsule Servings per container30 Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

Amino Renewal Complex

2.9 Gram(s) per serving

Other (inactive) ingredients: Gelatin, Magnesium Stearate, Stearic Acid, Silicon Dioxide, Titanium Dioxide, Rice Flour, Microcrystalline Cellulose, Candurin Silver Fine, Riboflavin, FD&C Yellow No. 5, FD&C Yellow No. 6. These complete the product’s ingredient list but are not active constituents.

Interaction report

SeroVital by SanMedica International Drug Interactions

Want to check YOUR meds against SeroVital?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
1,132Drugs
1 Major 1,127 Moderate 4 Minor

Ingredients driving the most interactions

Schizonepeta powder 797
L-Arginine Hydrochloride 403
N-Acetyl L-Cysteine 294
L-Glutamine 50
L-Lysine Hydrochloride 1

Individual Drug Interactions

The ingredients in SeroVital interact with 1,132 drugs. Click any drug to see the details.

5 of the 6 ingredients in SeroVital interact with drugs. Each result below shows which ingredient is responsible. Schizonepeta powder L-Arginine Hydrochloride N-Acetyl L-Cysteine L-Glutamine L-Lysine Hydrochloride

Each ingredient & the kinds of drugs it affects

For each ingredient in SeroVital with known interactions, here are the types of medications they can affect. Open any type for the detail — or search your exact drug in the checker above.

Schizonepeta powder4 drug types · 797 drugs

Cytochrome P450 1A2 (Cyp1A2) Substrates

Animal research suggests that schizonepetin, a monoterpene constituent of schizonepeta, inhibits cytochrome P450 (CYP) 1A2. Theoretically, schizonepeta might increase the effects and side effects of CYP1A2 substrates.
Some substrates of CYP1A2 include clozapine (Clozaril), cyclobenzaprine (Flexeril), fluvoxamine (Luvox), haloperidol (Haldol), imipramine (Tofranil), mexiletine (Mexitil), olanzapine (Zyprexa), pentazocine (Talwin), propranolol (Inderal), tacrine (Cognex), theophylline, zileuton (Zyflo), zolmitriptan (Zomig), and others.

Likelihood Possible Evidence D
Cytochrome P450 2D6 (Cyp2D6) Substrates

Animal research suggests that schizonepetin, a monoterpene constituent of schizonepeta, inhibits cytochrome P450 (CYP) 2D6. Theoretically, schizonepeta might increase the effects and side effects of CYP2D6 substrates.
Some substrates of CYP2D6 include amitriptyline (Elavil), codeine, desipramine (Norpramin), flecainide (Tambocor), haloperidol (Haldol), imipramine (Tofranil), metoprolol (Lopressor, Toprol XL), ondansetron (Zofran), paroxetine (Paxil), risperidone (Risperdal), tramadol (Ultram), venlafaxine (Effexor), and others.

Likelihood Possible Evidence D
Cytochrome P450 2E1 (Cyp2E1) Substrates

Animal research suggests that schizonepetin, a monoterpene constituent of schizonepeta, inhibits cytochrome P450 (CYP) 2E1. Theoretically, schizonepeta might increase the effects and side effects of CYP2E1 substrates.
Some substrates of CYP2E1 include acetaminophen, chlorzoxazone (Parafon Forte), ethanol, theophylline, and anesthetics such as enflurane (Ethrane), halothane (Fluothane), isoflurane (Forane), and methoxyflurane (Penthrane).

Likelihood Possible Evidence D
Cytochrome P450 3A4 (Cyp3A4) Substrates

Animal research suggests that schizonepetin, a monoterpene constituent of schizonepeta, induces cytochrome P450 (CYP) 3A4. Theoretically, schizonepeta might decrease the effects of CYP3A4 substrates.
Some substrates of CYP3A4 include lovastatin (Mevacor), ketoconazole (Nizoral), itraconazole (Sporanox), fexofenadine (Allegra), triazolam (Halcion), and numerous others.

Likelihood Possible Evidence D
Schizonepeta powder full monograph & interactions

L-Arginine Hydrochloride9 drug types · 403 drugs

Ace Inhibitors (Aceis)

Theoretically, concomitant use of L-arginine and ACE inhibitors may increase the risk for hypotension and hyperkalemia.
Combining L-arginine with some antihypertensive drugs, especially ACE inhibitors, seems to have additive vasodilating and blood pressure-lowering effects. Furthermore, ACE inhibitors can increase potassium levels. Use of L-arginine has been associated with hyperkalemia in some patients. Theoretically, concomitant use of ACE inhibitors with L-arginine may increases the risk of hyperkalemia.

Likelihood Probable Evidence D
Angiotensin Receptor Blockers (Arbs)

Theoretically, concomitant use of L-arginine and ARBs may increase the risk of hypotension and hyperkalemia.
L-arginine increases nitric oxide, which causes vasodilation. Combining L-arginine with ARBs seems to increase L-arginine-induced vasodilation. Furthermore, ARBs can increase potassium levels. Use of L-arginine has been associated with hyperkalemia in some patients. Theoretically, concomitant use of ARBs with L-arginine may increases the risk of hyperkalemia.

Likelihood Probable Evidence D
Anticoagulant/Antiplatelet Drugs

Theoretically, concomitant use of L-arginine with anticoagulant and antiplatelet drugs might have additive effects and increase the risk of bleeding.
Preliminary research suggests that L-arginine infusions reduce platelet aggregation in humans. The clinical significance of this effect is unclear.

Likelihood Possible Evidence D
Antidiabetes Drugs

Theoretically, concomitant use of L-arginine might have additive effects with antidiabetes drugs.
Preliminary clinical research shows that L-arginine decreases blood glucose levels in patients with type 2 diabetes.

Likelihood Possible Evidence D
Antihypertensive Drugs

Theoretically, concomitant use of L-arginine and antihypertensive drugs may increase the risk of hypotension.
L-arginine increases nitric oxide, which causes vasodilation. Clinical evidence shows that L-arginine can reduce blood pressure in some individuals with hypertension. Furthermore, combining L-arginine with some antihypertensive drugs seems to have additive vasodilating and blood pressure-lowering effects.

Likelihood Probable Evidence D
Isoproterenol (Isuprel)

Theoretically, concurrent use of isoproterenol and L-arginine might result in additive effects and hypotension.
Preliminary clinical evidence suggests that L-arginine enhances isoproterenol-induced vasodilation in patients with essential hypertension or a family history of essential hypertension.

Likelihood Probable Evidence D
Potassium-Sparing Diuretics

Theoretically concomitant use of potassium-sparing diuretics with L-arginine may increases the risk of hyperkalemia.
Potassium-sparing diuretics can increase potassium levels. Use of L-arginine has been associated with hyperkalemia in some patients.

Likelihood Possible Evidence D
Sildenafil (Viagra)

Theoretically, concurrent use of sildenafil and L-arginine might increase the risk for hypotension.
In vivo, concurrent use of L-arginine and sildenafil has resulted in increased vasodilation. Theoretically, concurrent use might have additive vasodilatory and hypotensive effects. However, in studies evaluating the combined use of L-arginine and sildenafil for erectile dysfunction, hypotension was not reported.

Likelihood Possible Evidence D
Testosterone

Theoretically, concomitant use of L-arginine and testosterone might have additive effects.
In clinical research, L-arginine increases the level of testosterone in male patients with erectile dysfunction. The clinical significance of this finding is unclear.

Likelihood Possible Evidence D
L-Arginine Hydrochloride full monograph & interactions

N-Acetyl L-Cysteine5 drug types · 294 drugs

Nitroglycerin

N-acetyl cysteine can increase the risk for hypotension and headaches when taken with intravenous or transdermal nitroglycerin.
Clinical research shows that concomitant administration of N-acetyl cysteine and intravenous or transdermal nitroglycerin can cause severe hypotension and intolerable headaches. Furthermore, in vitro research suggests that N-acetyl cysteine increases the anticoagulant activity of nitroglycerin.

Likelihood Probable Evidence B
Activated Charcoal

N-acetyl cysteine might reduce the effects of activated charcoal, while activated charcoal might reduce the absorption of N-acetyl cysteine.
N-acetyl cysteine appears to reduce the capacity of activated charcoal to adsorb acetaminophen and salicylic acid. Conversely, although clinical research suggests that although activated charcoal can reduce the absorption of N-acetyl cysteine by up to 40%, it does not seem to reduce its clinical effects. Other clinical evidence suggests that activated charcoal does not affect the absorption of N-acetyl cysteine.

Likelihood Possible Evidence D
Anticoagulant/Antiplatelet Drugs

Theoretically, N-acetyl cysteine might increase the risk of bleeding when taken with anticoagulant or antiplatelet drugs.
Clinical research suggests that intravenous N-acetyl cysteine decreases prothrombin time, prolongs coagulation time, decreases platelet aggregation, and increases blood loss in surgical patients. Furthermore, in vitro research suggests that N-acetyl cysteine increases the anticoagulant activity of nitroglycerin.

Likelihood Possible Evidence D
Antihypertensive Drugs

Theoretically, N-acetyl cysteine might increase the risk of hypotension when taken with antihypertensive drugs.
Animal research suggests that N-acetyl cysteine potentiates the hypotensive effects of the angiotensin-converting enzyme inhibitors (ACEIs) captopril and enalaprilat. Theoretically, combining N-acetyl cysteine with other antihypertensive drugs might increase the risk of hypotension.

Likelihood Possible Evidence D
Chloroquine (Aralen)

Theoretically, N-acetyl cysteine might interfere with the antimalarial effects of chloroquine.
Animal research suggests that N-acetyl cysteine might reduce the antimalarial effects of chloroquine by increasing cellular levels of glutathione.

Likelihood Possible Evidence D
N-Acetyl L-Cysteine full monograph & interactions

L-Glutamine1 drug type · 50 drugs

Anticonvulsants

Theoretically, glutamine might antagonize the effects of anticonvulsant medications.
Glutamine is metabolized to the excitatory neurotransmitter glutamate. Glutamate might have antagonistic effects with anticonvulsant drugs. However, this interaction has not yet been reported in humans.

Likelihood Possible Evidence D
L-Glutamine full monograph & interactions

L-Lysine Hydrochloride1 drug type · 1 drug

5-Ht4 Agonists

Theoretically, lysine may reduce the effects of 5-HT4 agonists.
Animal research suggests that L-lysine is a partial serotonin receptor 4 (5-HT4) antagonist and inhibits diarrhea induced by the 5-HT4 agonist, 5-hydroxytryptophane.

Likelihood Unlikely Evidence D
L-Lysine Hydrochloride full monograph & interactions
The maker

Brand information

Manufacturer and brand details for SeroVital, from the product label.

SanMedica International

See all SanMedica International products
Name
SanMedica International, LLC
City
Salt Lake City
State
UT
ZipCode
84116
Phone Number
1-800-898-5153
Pharmacist Counseling Corner

SeroVital by SanMedica International: Common Questions

Does SeroVital by SanMedica International interact with any medications?
Yes. Based on its ingredients, SeroVital has a known interaction with 1,132 medications, including 1 rated major. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
SeroVital contains 6 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Is SeroVital safe to take if I'm pregnant or breastfeeding?
L-glutamine is rated Likely Safe in pregnancy, but the other amino acids and schizonepeta don't have enough safety data to know either way. Schizonepeta is advised against in both pregnancy and breastfeeding. Talk with your doctor or pharmacist before taking this product if you're pregnant or breastfeeding — they can weigh the risks and benefits for your situation.
What are the most common side effects of SeroVital?
The amino acids in this product most commonly cause digestive upset — bloating, gas, constipation, diarrhea, stomach pain, nausea, and vomiting. You may also experience headache, dry mouth, or flushing. These are usually mild, but if they're bothersome or don't improve, let your pharmacist know.
Can this product help with anti-aging or growth hormone?
The data we hold shows no effectiveness ratings for most of these ingredients for anti-aging or growth hormone claims. L-glutamine is Possibly Effective for postoperative recovery and HIV/AIDS-related wasting, and L-lysine has Insufficient Evidence for child growth. If anti-aging is your goal, the evidence in our data doesn't support it.
Does SeroVital contain any fillers?
Yes — it contains inactive ingredients like magnesium stearate, microcrystalline cellulose, rice flour, gelatin, and several colorants and other excipients. These are standard in capsule formulas and serve as binders and flow agents.
What's the difference between the amino acids in this product?
Each has different roles. L-glutamine supports certain conditions like sickle cell disease and recovery from illness. L-lysine is Possibly Effective for cold sores. L-arginine increases nitric oxide and may lower blood pressure. N-acetyl cysteine (NAC) is used for acetaminophen poisoning and respiratory support. They're not interchangeable.
Can I take SeroVital long-term?
Long-term safety data is limited for most of these ingredients. L-glutamine is not well studied long-term at supplement doses. One rare case of kidney injury was reported with long-term lysine use. If you're considering long-term use, discuss it with your pharmacist or doctor — they can monitor you appropriately.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

SeroVital label
Go deeper

The Full Monographs Behind SeroVital’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Glutamine

Interacts with 50 drugs

Glutamine is the most abundant amino acid in the body and is usually made in your muscles. A prescription form is FDA-approved to help reduce sickle cell disease complications, but for most...

Read the full Glutamine monograph → Herb & supplement monograph

Lysine

Interacts with 1 drug

Lysine is an essential amino acid your body cannot make on its own, so it must come from food or supplements. People most often take extra lysine to try to prevent or shorten cold sores, but...

Read the full Lysine monograph → Herb & supplement monograph

N-acetyl Cysteine (nac)

Interacts with 294 drugs

N-acetyl cysteine (NAC) is a supplement form of the amino acid cysteine and a building block for the antioxidant glutathione. It has well-established prescription uses for acetaminophen over...

Read the full N-acetyl Cysteine (nac) monograph → Herb & supplement monograph

L-arginine

Interacts with 403 drugs

L-arginine is an amino acid that the body uses to make nitric oxide, a substance that helps blood vessels relax and widen. It is popularly used for blood pressure, erectile dysfunction, and...

Read the full L-arginine monograph → Herb & supplement monograph

Schizonepeta

Interacts with 797 drugs

Schizonepeta is a mint-family herb long used in traditional Chinese medicine, usually as part of combination formulas for colds, fevers, and itchy skin conditions. Modern human evidence is v...

Read the full Schizonepeta monograph →
Sources

Sources & How We Checked

SeroVital's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 174 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Glutamine 11 references
  1. Miller AL. Therapeutic considerations of L-glutamine: a review of the literature. Altern Med Rev 1999;4:239-48..
  2. Bozzetti F, Biganzoli L, Gavazzi C, et al. Glutamine supplementation in cancer patients receiving chemotherapy: a double-blind randomized study. Nutrition 1997;13:748-51.. PubMed
  3. Mebane AH. L-Glutamine and mania. Am J Psychiatry 984;141:1302-3.
  4. Meldrum BS. Glutamate as a neurotransmitter in the brain: review of physiology and pathology. J Nutr 2000;130:1007S-15S.. PubMed
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Lysine 7 references
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N-acetyl Cysteine (nac) 86 references
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L-arginine 66 references
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Schizonepeta 4 references
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DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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