Slippery Elm Inner Bark Ingredients & Drug Interactions
by Gaia Herbs
What is this page for?
First and foremost: checking Slippery Elm Inner Bark against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.
Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy
Slippery Elm Inner Bark is a dietary supplement by Gaia Herbs with 3 active ingredients. Its ingredients are commonly taken for sore throat and cough, heartburn and acid reflux, digestive upset and ibs.Based on those ingredients, 2,022 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Slippery Elm inner bark extract. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.
Check Your Meds Against Slippery Elm Inner Bark by Gaia Herbs
Ask about any prescription or over-the-counter medication and we check it for interactions with Slippery Elm Inner Bark by Gaia Herbs — and tell you which ingredient is responsible.
AI summaries are generated from our interaction database for education only — always confirm with your pharmacist. How we use AI
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HelloPharmacist Scorecard of Slippery Elm Inner Bark by Gaia Herbs
Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.
What’s inside
Low disclosure
This liquid contains 3 ingredients. The active component is slippery elm inner bark extract, a demulcent (soothing agent) traditionally used for digestive and throat comfort.
The extract is suspended in water and 25–35% pure grain alcohol, which acts as both a solvent and preservative.
Does it work?
Couldn't assess
The evidence we have on file doesn't establish that slippery elm works for cancer, constipation, cough, inflammatory bowel disease, or diarrhea — the ratings across all these uses are insufficient. That doesn't mean it doesn't help; it means high-quality studies backing it up aren't yet in our data.
How safe is it?
Well-documented data
Slippery elm is generally well tolerated for short-term use, though rigorous safety data are limited. Contact dermatitis and allergic reactions (urticaria) have been reported, particularly with topical exposure or if you're sensitive to slippery elm pollen.
During pregnancy, there isn't enough reliable safety data — talk with your doctor or pharmacist about whether it's right for you. For breastfeeding, too little information exists on safety, so caution is advised; check with your doctor or pharmacist before use.
Meds to double-check
Moderate interaction found
Before you take this product, double-check your oral medications — slippery elm may slow their absorption and reduce how well they work. Altogether, these interactions span 2,023 individual medications, so use the interaction checker on this page and confirm with your own doctor or pharmacist.
The bottom line
Scorecard at a glanceFormula with limited ingredient disclosure with no assessable stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.
Slippery Elm Inner Bark is generally well tolerated for short-term use, but its mucilage can slow oral drug absorption — a real concern if you take medications by mouth. If you're on any oral medications, check them against the interaction tool and talk with your doctor or pharmacist before adding this product.
Effectiveness for its common uses hasn't been established in our data.
Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI
Assessment coverage: 1 of 3 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Jan 25, 2013.
This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed
General information
Key facts about Slippery Elm Inner Bark, straight from the product label.
| Brand | Gaia Herbs |
|---|---|
| Barcode (UPC) | 751063310604 |
| Net contents | 1 fl. Oz.; 30 mL |
| Market status | On market |
| Date entered into DSLD | Jan 25, 2013 |
| DSLD ID | 16447 |
| Product type | Other Combinations |
| Supplement form | Liquid |
| Dietary claims / uses | All Other |
| Intended target group(s) | Adult (18 - 50 Years) |
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.
Supplement Facts
The label details for Slippery Elm Inner Bark by Gaia Herbs, sourced from the NIH Dietary Supplement Label Database.
Supplement Facts
| Ingredient | Amount | % DV |
|---|---|---|
| Water | 0 NP | -- |
| 25-35% Pure Grain Alcohol | 0 NP | -- |
| Slippery Elm inner bark extract | 0 NP | -- |
Tap any ingredient to jump to its full detail below.
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Precautions
Not to be used during pregnancy or lactation. If you have a medical condition or take pharmaceutical drugs, please consult with your doctor before use.
Keep away from children.
Use only as directed on label. Safety sealed for your protection.
General Statements
Liquid Herbal Extract
333 mg/ml herb equivalency
FDA Statement of Identity
DIETARY SUPPLEMENT
Suggested/Recommended/Usage/Directions
Suggested Use Take 40-60 drops of extract in a small amount of water 3-4 times daily between meals. Shake well before using.
General
[03] 1093-0510
Is this label outdated? Report a formula or label change and our pharmacy team will review it.
Slippery Elm Inner Bark by Gaia Herbs label
The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.
Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.
View the full label (PDF)The Ingredients in Slippery Elm Inner Bark by Gaia Herbs
These are the 3 active ingredients this product is made of. Select any to open its full monograph.
Serving size1.33 mL Dosage formLiquid Servings per container23 Amounts shown are per serving.
Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.
Water
25-35% Pure Grain Alcohol
Slippery Elm inner bark extract
Interacts with2,022 drugs
Slippery elm is a traditional herbal remedy made from the inner bark of a North American elm tree, used mainly to soothe sore throats and irritated di...
Slippery Elm inner bark extract monograph & interactionsSlippery Elm Inner Bark by Gaia Herbs Drug Interactions
HelloPharmacist Interaction Report
Gaia Herbs Slippery Elm Inner Bark does interact with medications through its slippery elm extract.
The main concern is a Moderate interaction with oral drugs — the mucilage in slippery elm may slow how your body absorbs medications you take by mouth and lower the levels they reach in your bloodstream.
Read the full breakdown — every affected drug type, severity by severity
Because slippery elm can potentially affect oral drug absorption, you'll want to space out when you take this product and your oral medications. Altogether, these interactions span 2,023 individual medications.
The best approach is to take slippery elm at least two hours apart from any oral drugs — but check the specific medications you're on using the interaction checker below, and run it past your doctor or pharmacist before you start.
We weren't able to check the water and grain alcohol in this formula — we hold no interaction data for those ingredients.
Check your own medications below · Editorial policy · How we use AI
Want to check YOUR meds against Slippery Elm Inner Bark?
Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.
Go to the checkerIngredients driving the most interactions
Individual Drug Interactions
The ingredients in Slippery Elm Inner Bark interact with 2,022 drugs. Click any drug to see the details.
1 of the 3 ingredients in Slippery Elm Inner Bark interact with drugs. Each result below shows which ingredient is responsible. Slippery Elm inner bark extract
TrioxsalenTrisoralen
How Trioxsalen interacts with Slippery Elm Inner Bark — through 1 ingredient. Tap an ingredient for the detail:
Slippery Elm Inner Bark ExtractOral Drugs Moderate
Interaction Summary
Theoretically, slippery elm may slow the absorption and reduce serum levels of oral drugs.
Read the full Slippery Elm Inner Bark Extract + Trioxsalen interactionTripelennaminePBZ, PBZ-SR
How Tripelennamine interacts with Slippery Elm Inner Bark — through 1 ingredient. Tap an ingredient for the detail:
Slippery Elm Inner Bark ExtractOral Drugs Moderate
Interaction Summary
Theoretically, slippery elm may slow the absorption and reduce serum levels of oral drugs.
Read the full Slippery Elm Inner Bark Extract + Tripelennamine interactionTrofinetideDaybue
How Trofinetide interacts with Slippery Elm Inner Bark — through 1 ingredient. Tap an ingredient for the detail:
Slippery Elm Inner Bark ExtractOral Drugs Moderate
Interaction Summary
Theoretically, slippery elm may slow the absorption and reduce serum levels of oral drugs.
Read the full Slippery Elm Inner Bark Extract + Trofinetide interactionTroglitazoneRezulin
How Troglitazone interacts with Slippery Elm Inner Bark — through 1 ingredient. Tap an ingredient for the detail:
Slippery Elm Inner Bark ExtractOral Drugs Moderate
Interaction Summary
Theoretically, slippery elm may slow the absorption and reduce serum levels of oral drugs.
Read the full Slippery Elm Inner Bark Extract + Troglitazone interactionTroleandomycinTao
How Troleandomycin interacts with Slippery Elm Inner Bark — through 1 ingredient. Tap an ingredient for the detail:
Slippery Elm Inner Bark ExtractOral Drugs Moderate
Interaction Summary
Theoretically, slippery elm may slow the absorption and reduce serum levels of oral drugs.
Read the full Slippery Elm Inner Bark Extract + Troleandomycin interactionTrospiumRegurin, Sanctura, Trosec
How Trospium interacts with Slippery Elm Inner Bark — through 1 ingredient. Tap an ingredient for the detail:
Slippery Elm Inner Bark ExtractOral Drugs Moderate
Interaction Summary
Theoretically, slippery elm may slow the absorption and reduce serum levels of oral drugs.
Read the full Slippery Elm Inner Bark Extract + Trospium interactionTrovafloxacinTrovan, Trovan Injection
How Trovafloxacin interacts with Slippery Elm Inner Bark — through 1 ingredient. Tap an ingredient for the detail:
Slippery Elm Inner Bark ExtractOral Drugs Moderate
Interaction Summary
Theoretically, slippery elm may slow the absorption and reduce serum levels of oral drugs.
Read the full Slippery Elm Inner Bark Extract + Trovafloxacin interactionTrypan BlueVisionBlue
How Trypan Blue interacts with Slippery Elm Inner Bark — through 1 ingredient. Tap an ingredient for the detail:
Slippery Elm Inner Bark ExtractOral Drugs Moderate
Interaction Summary
Theoretically, slippery elm may slow the absorption and reduce serum levels of oral drugs.
Read the full Slippery Elm Inner Bark Extract + Trypan Blue interactionTucatinibTukysa
How Tucatinib interacts with Slippery Elm Inner Bark — through 1 ingredient. Tap an ingredient for the detail:
Slippery Elm Inner Bark ExtractOral Drugs Moderate
Interaction Summary
Theoretically, slippery elm may slow the absorption and reduce serum levels of oral drugs.
Read the full Slippery Elm Inner Bark Extract + Tucatinib interactionTyropanoateBilopaque
How Tyropanoate interacts with Slippery Elm Inner Bark — through 1 ingredient. Tap an ingredient for the detail:
Slippery Elm Inner Bark ExtractOral Drugs Moderate
Interaction Summary
Theoretically, slippery elm may slow the absorption and reduce serum levels of oral drugs.
Read the full Slippery Elm Inner Bark Extract + Tyropanoate interactionUbrogepantUbrelvy
How Ubrogepant interacts with Slippery Elm Inner Bark — through 1 ingredient. Tap an ingredient for the detail:
Slippery Elm Inner Bark ExtractOral Drugs Moderate
Interaction Summary
Theoretically, slippery elm may slow the absorption and reduce serum levels of oral drugs.
Read the full Slippery Elm Inner Bark Extract + Ubrogepant interactionUlipristal AcetateElla
How Ulipristal Acetate interacts with Slippery Elm Inner Bark — through 1 ingredient. Tap an ingredient for the detail:
Slippery Elm Inner Bark ExtractOral Drugs Moderate
Interaction Summary
Theoretically, slippery elm may slow the absorption and reduce serum levels of oral drugs.
Read the full Slippery Elm Inner Bark Extract + Ulipristal Acetate interactionUmbralisib TosylateUkoniq
How Umbralisib Tosylate interacts with Slippery Elm Inner Bark — through 1 ingredient. Tap an ingredient for the detail:
Slippery Elm Inner Bark ExtractOral Drugs Moderate
Interaction Summary
Theoretically, slippery elm may slow the absorption and reduce serum levels of oral drugs.
Read the full Slippery Elm Inner Bark Extract + Umbralisib Tosylate interactionUmeclidinium BromideIncruse Ellipta
How Umeclidinium Bromide interacts with Slippery Elm Inner Bark — through 1 ingredient. Tap an ingredient for the detail:
Slippery Elm Inner Bark ExtractOral Drugs Moderate
Interaction Summary
Theoretically, slippery elm may slow the absorption and reduce serum levels of oral drugs.
Read the full Slippery Elm Inner Bark Extract + Umeclidinium Bromide interactionUndecylenic AcidDesenex
How Undecylenic Acid interacts with Slippery Elm Inner Bark — through 1 ingredient. Tap an ingredient for the detail:
Slippery Elm Inner Bark ExtractOral Drugs Moderate
Interaction Summary
Theoretically, slippery elm may slow the absorption and reduce serum levels of oral drugs.
Read the full Slippery Elm Inner Bark Extract + Undecylenic Acid interactionUnoprostoneRescula
How Unoprostone interacts with Slippery Elm Inner Bark — through 1 ingredient. Tap an ingredient for the detail:
Slippery Elm Inner Bark ExtractOral Drugs Moderate
Interaction Summary
Theoretically, slippery elm may slow the absorption and reduce serum levels of oral drugs.
Read the full Slippery Elm Inner Bark Extract + Unoprostone interactionUpadacitinib HemihydrateRinvoq
How Upadacitinib Hemihydrate interacts with Slippery Elm Inner Bark — through 1 ingredient. Tap an ingredient for the detail:
Slippery Elm Inner Bark ExtractOral Drugs Moderate
Interaction Summary
Theoretically, slippery elm may slow the absorption and reduce serum levels of oral drugs.
Read the full Slippery Elm Inner Bark Extract + Upadacitinib Hemihydrate interactionUracil MustardUramustine
How Uracil Mustard interacts with Slippery Elm Inner Bark — through 1 ingredient. Tap an ingredient for the detail:
Slippery Elm Inner Bark ExtractOral Drugs Moderate
Interaction Summary
Theoretically, slippery elm may slow the absorption and reduce serum levels of oral drugs.
Read the full Slippery Elm Inner Bark Extract + Uracil Mustard interactionUreaUreaphil
How Urea interacts with Slippery Elm Inner Bark — through 1 ingredient. Tap an ingredient for the detail:
Slippery Elm Inner Bark ExtractOral Drugs Moderate
Interaction Summary
Theoretically, slippery elm may slow the absorption and reduce serum levels of oral drugs.
Read the full Slippery Elm Inner Bark Extract + Urea interactionUridine TriacetateVistogard, Xuriden
How Uridine Triacetate interacts with Slippery Elm Inner Bark — through 1 ingredient. Tap an ingredient for the detail:
Slippery Elm Inner Bark ExtractOral Drugs Moderate
Interaction Summary
Theoretically, slippery elm may slow the absorption and reduce serum levels of oral drugs.
Read the full Slippery Elm Inner Bark Extract + Uridine Triacetate interactionUrinary Antiseptic #2Hexalol
How Urinary Antiseptic #2 interacts with Slippery Elm Inner Bark — through 1 ingredient. Tap an ingredient for the detail:
Slippery Elm Inner Bark ExtractOral Drugs Moderate
Interaction Summary
Theoretically, slippery elm may slow the absorption and reduce serum levels of oral drugs.
Read the full Slippery Elm Inner Bark Extract + Urinary Antiseptic #2 interactionUrinary Antiseptic Comb. (veterinary)Urinary Antiseptic
How Urinary Antiseptic Comb. (veterinary) interacts with Slippery Elm Inner Bark — through 1 ingredient. Tap an ingredient for the detail:
Slippery Elm Inner Bark ExtractOral Drugs Moderate
Interaction Summary
Theoretically, slippery elm may slow the absorption and reduce serum levels of oral drugs.
Read the full Slippery Elm Inner Bark Extract + Urinary Antiseptic Comb. (veterinary) interactionUrinary Tract CombinationUritabs
How Urinary Tract Combination interacts with Slippery Elm Inner Bark — through 1 ingredient. Tap an ingredient for the detail:
Slippery Elm Inner Bark ExtractOral Drugs Moderate
Interaction Summary
Theoretically, slippery elm may slow the absorption and reduce serum levels of oral drugs.
Read the full Slippery Elm Inner Bark Extract + Urinary Tract Combination interactionUrokinaseAbbokinase
How Urokinase interacts with Slippery Elm Inner Bark — through 1 ingredient. Tap an ingredient for the detail:
Slippery Elm Inner Bark ExtractOral Drugs Moderate
Interaction Summary
Theoretically, slippery elm may slow the absorption and reduce serum levels of oral drugs.
Read the full Slippery Elm Inner Bark Extract + Urokinase interactionUrsodeoxycholic AcidUrso
How Ursodeoxycholic Acid interacts with Slippery Elm Inner Bark — through 1 ingredient. Tap an ingredient for the detail:
Slippery Elm Inner Bark ExtractOral Drugs Moderate
Interaction Summary
Theoretically, slippery elm may slow the absorption and reduce serum levels of oral drugs.
Read the full Slippery Elm Inner Bark Extract + Ursodeoxycholic Acid interactionUrsodiolActigall
How Ursodiol interacts with Slippery Elm Inner Bark — through 1 ingredient. Tap an ingredient for the detail:
Slippery Elm Inner Bark ExtractOral Drugs Moderate
Interaction Summary
Theoretically, slippery elm may slow the absorption and reduce serum levels of oral drugs.
Read the full Slippery Elm Inner Bark Extract + Ursodiol interactionVadadustatVafseo
How Vadadustat interacts with Slippery Elm Inner Bark — through 1 ingredient. Tap an ingredient for the detail:
Slippery Elm Inner Bark ExtractOral Drugs Moderate
Interaction Summary
Theoretically, slippery elm may slow the absorption and reduce serum levels of oral drugs.
Read the full Slippery Elm Inner Bark Extract + Vadadustat interactionValacyclovirValtrex
How Valacyclovir interacts with Slippery Elm Inner Bark — through 1 ingredient. Tap an ingredient for the detail:
Slippery Elm Inner Bark ExtractOral Drugs Moderate
Interaction Summary
Theoretically, slippery elm may slow the absorption and reduce serum levels of oral drugs.
Read the full Slippery Elm Inner Bark Extract + Valacyclovir interactionValbenazine TosylateIngrezza
How Valbenazine Tosylate interacts with Slippery Elm Inner Bark — through 1 ingredient. Tap an ingredient for the detail:
Slippery Elm Inner Bark ExtractOral Drugs Moderate
Interaction Summary
Theoretically, slippery elm may slow the absorption and reduce serum levels of oral drugs.
Read the full Slippery Elm Inner Bark Extract + Valbenazine Tosylate interactionValdecoxibBextra
How Valdecoxib interacts with Slippery Elm Inner Bark — through 1 ingredient. Tap an ingredient for the detail:
Slippery Elm Inner Bark ExtractOral Drugs Moderate
Interaction Summary
Theoretically, slippery elm may slow the absorption and reduce serum levels of oral drugs.
Read the full Slippery Elm Inner Bark Extract + Valdecoxib interactionEach ingredient & the kinds of drugs it affects
For each ingredient in Slippery Elm Inner Bark with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.
Slippery Elm inner bark extract
Oral Drugs
Theoretically, slippery elm may slow the absorption and reduce serum levels of oral drugs.
Slippery elm inner bark contains mucilage, which may interfere with the absorption of orally administered drugs.
Brand information
Manufacturer and brand details for Slippery Elm Inner Bark, from the product label.
Slippery Elm Inner Bark by Gaia Herbs: Common Questions
Does Slippery Elm Inner Bark by Gaia Herbs interact with any medications?
How can one product interact with so many drugs?
Where does this information come from?
Can I take this if I'm pregnant?
Is slippery elm safe while breastfeeding?
What is slippery elm supposed to do?
Can I take this with all my medications?
What's in this liquid besides the slippery elm?
Are there any side effects I should know about?
Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
Not sure if Slippery Elm Inner Bark is safe with your meds?
Our pharmacists answer your medication & supplement questions — free.
Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.
The Full Monographs Behind Slippery Elm Inner Bark’s Ingredients
Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.
Sources & How We Checked
Slippery Elm Inner Bark's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.
- NIH Dietary Supplement Label Database (DSLD) — The official product label on file for this supplement.
- Natural Medicines (Therapeutic Research Center) — Evidence-graded clinical reference behind the ingredient interaction data.
Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.
The 3 references behind this product’s interaction data
Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.
Slippery Elm 3 references
- The Review of Natural Products by Facts and Comparisons. St. Louis, MO: Wolters Kluwer Co., 1999.
- Brinker F. Herb Contraindications and Drug Interactions. 2nd ed. Sandy, OR: Eclectic Medical Publications, 1998.
- Czarnecki D, Nixon R, Bekhor P, and et al. Delayed prolonged contact urticaria from the elm tree. Contact Dermatitis 1993;28:196-197. PubMed
Parts of this content are provided by the Therapeutic Research Center, LLC.
DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.
© 2021 Therapeutic Research Center, LLC