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Dietary supplement

Turkey Tail Mushroom Ingredients & Drug Interactions

by Gaia Herbs

Turkey Tail Mushroom label
See full label image
Capsule Category: Botanical
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 9, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Turkey Tail Mushroom against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Turkey Tail Mushroom is a dietary supplement by Gaia Herbs with 1 active ingredient. Its ingredients are commonly taken for high cholesterol, heart health, immune support.Based on those ingredients, 293 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Beta Glucans. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

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Check Your Meds Against Turkey Tail Mushroom by Gaia Herbs

Ask about any prescription or over-the-counter medication and we check it for interactions with Turkey Tail Mushroom by Gaia Herbs — and tell you which ingredient is responsible.

Pharmacist-reviewed data Checks every ingredient Answer in seconds
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HelloPharmacist Scorecard of Turkey Tail Mushroom by Gaia Herbs

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Jul 11, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • “Turkey Tails fruiting body Extract” is listed as a grouped ingredient — the label gives one combined amount (400 mg) without saying how much of each component you get.

This product contains one active ingredient: beta-glucans extracted from turkey tail mushroom. Beta-glucans are compounds naturally found in mushrooms and other foods that your immune system recognizes and responds to.

The capsule itself is made with pullulan, an inactive ingredient that helps hold everything together.

Does it work?

Not established
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not established

The graded evidence we hold for these ingredients covers different conditions than the ones this product is marketed for, so there's no established rating for its stated use — see Beta-glucans's own graded uses on its monograph.

Why this rating?
  • The label markets this product for: Immune and liver support.
  • We looked for evidence on: Hepatitis, Lower respiratory tract infections, Upper respiratory tract infection (URTI), Exercise-induced respiratory infections, Critical illness (trauma), Wound healing — and 3 related terms.
  • The closest evidence on file: Beta-glucans is rated "Insufficient Reliable Evidence To Rate" for Upper respiratory tract infection (URTI) (Natural Medicines).
  • Also on file: Beta-glucans is rated "Insufficient Reliable Evidence To Rate" for Exercise-induced respiratory infections, Hepatitis, Lower respiratory tract infections, Wound healing, and more.

Beta-glucans in this product are rated likely effective for two conditions: dyslipidemia (high cholesterol) and coronary heart disease. That means there's solid clinical research supporting their use for these purposes.

If you're taking this for either of those reasons, the evidence backs you up.

The evidence, ingredient by ingredient Beta-glucans

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Beta-glucans from food sources are generally well tolerated, though the safety data for concentrated supplements like this one is thinner than we'd like. Use it with the understanding that long-term supplement safety data isn't as robust.

Topically applied beta-glucans can cause skin reactions and contact dermatitis in some people, though these tend to be mild and self-resolving. One person in a clinical trial developed temporary elevation of liver enzymes after starting a very high dose; at standard supplement doses, liver concerns haven't been a pattern.

There isn't enough safety data on supplement doses during breastfeeding, so talk with your pharmacist or doctor if you're nursing.

Side effects, ingredient by ingredient Beta-glucans

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Beta-glucans.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: immunosuppressants / transplant drugs.
  • For scale: 293 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Check before starting if you take blood pressure medications (antihypertensive drugs) — beta-glucans may lower your pressure further — or if you take immunosuppressants after a transplant or for autoimmune disease, since beta-glucans stimulate the immune system you're trying to dampen. Both are Moderate-severity interactions.

Use the medication search tool on this page to verify your specific prescriptions.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with no established evidence rating for its marketed use. Moderate medication interactions have been identified, and safety information is well characterized.

Turkey Tail Mushroom by Gaia Herbs is backed by research for cholesterol and heart health, and beta-glucans are generally well tolerated. If you take blood pressure medications or immunosuppressants, you need to check with us first — the interactions are real.

Even if you're not on those drugs, run your full medication list through the checker before starting.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Sep 22, 2022.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Turkey Tail Mushroom, straight from the product label.

Brand Gaia Herbs
Net contents 40 Vegan Capsule(s)
Market status On market
Date entered into DSLD Sep 22, 2022
DSLD ID 273407
Product type Botanical
Supplement form Capsule
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years), Women (not pregnant or lactating), Organic, Gluten Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Turkey Tail Mushroom by Gaia Herbs, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Capsule(s)
Maximum serving Sizes:
1 Capsule(s)
Servings per container
40
IngredientAmount% DV
Beta Glucans135 mg--
Turkey Tails fruiting body Extract400 mg--

Other ingredients: Pullulan

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Brand IP Statement(s)

Gaia Herbs EST 1987

Formulation

Immune & liver support

6X strength

Non GMO Project Verified nongmoproject.org

Certified Organic by Oregon Tilth.

Natural separation may occur. This does not affect product quality.

No grain & rice fillers Gluten free

Sustainably sourced Guaranteed beta glucan levels

Formula

Only fruiting body extracts Made with organic mushrooms

The Gaia Difference Organic mushrooms Only fruiting bodies

Why Fruiting Bodies? We use only the fruiting bodies of mushrooms, as the concentration of active beneficial compounds like beta glucans is greatest in this part vs. the mycelium.

Seals/Symbols

Non GMO Project Verified nongmoproject.org

Certified B Corporation

Suggested/Recommended/Usage/Directions

One A Day

Suggested Use Adults take 1 capsule once daily. Benefits build over time.

FDA Statement of Identity

Herbal Supplement

Precautions

Warning: Reproductive Harm-www.P65Warnings.ca.gov/food

Not for use during pregnancy or lactation. If you have a medical condition or take medications, please consult with your doctor before use.

Store away from children.

Use only as directed on label. Safety-sealed for your protection.

Storage

Keep bottle capped at all times and store in a cool, dry place.

General Statements

Gaia Herbs delivers unprecedented traceability by screening every product and sharing the results online. To learn more, enter the unique ID # below at meetyourherbs.com.

Discover our guiding truths at: Facebook Instagram @gaiaherbs

Fruiting Body - Cap Gills Stem Mycelium

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Turkey Tail Mushroom by Gaia Herbs label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Turkey Tail Mushroom label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Turkey Tail Mushroom by Gaia Herbs

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size1 Capsule(s) Dosage formCapsule Servings per container40 Amounts shown are per serving.

Turkey Tails fruiting body Extract

400 mg per serving

Other (inactive) ingredients: Pullulan. These complete the product’s ingredient list but are not active constituents.

Interaction report

Turkey Tail Mushroom by Gaia Herbs Drug Interactions

Want to check YOUR meds against Turkey Tail Mushroom?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
293Drugs
293 Moderate

Ingredients driving the most interactions

Beta Glucans 293

Individual Drug Interactions

The ingredients in Turkey Tail Mushroom interact with 293 drugs. Click any drug to see the details.

1 of the 1 ingredient in Turkey Tail Mushroom interact with drugs. Each result below shows which ingredient is responsible. Beta Glucans

Each ingredient & the kinds of drugs it affects

For each ingredient in Turkey Tail Mushroom with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Beta Glucans2 drug types · 293 drugs

Antihypertensive Drugs

Theoretically, taking beta-glucans with antihypertensive drugs might increase the risk of hypotension.
Clinical research shows that taking beta-glucans may reduce systolic and diastolic blood pressure in some hypertensive individuals.

Likelihood Possible Evidence D
Immunosuppressants

Theoretically, beta-glucans might interfere with immunosuppressive therapy.
Some clinical research shows that beta-glucans have immunostimulant effects.

Likelihood Possible Evidence D
Beta Glucans full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Turkey Tail Mushroom, from the product label.

Gaia Herbs

See all Gaia Herbs products
Name
Gaia Herbs, Inc.
Street Address
101 Gaia Herbs Drive
City
Brevard
State
NC
ZipCode
28712
Web Address
www.gaiaherbs.com
Pharmacist Counseling Corner

Turkey Tail Mushroom by Gaia Herbs: Common Questions

Does Turkey Tail Mushroom by Gaia Herbs interact with any medications?
Yes. Based on its ingredients, Turkey Tail Mushroom has a known interaction with 293 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Turkey Tail Mushroom contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Is this safe to take if I'm breastfeeding?
There isn't enough research on supplement doses of beta-glucans during breastfeeding to say for sure either way. Talk with your pharmacist or doctor about whether this product makes sense for you right now.
Does this actually help with cholesterol and heart health?
Yes — beta-glucans are rated likely effective for both high cholesterol and coronary heart disease, meaning clinical studies support their use for these conditions.
What are the side effects?
Beta-glucans are generally well tolerated when taken by mouth. In topical applications, some people have reported mild skin reactions or contact dermatitis. One patient in a trial developed temporary liver enzyme elevation at a very high dose, but this hasn't been a common pattern at typical supplement doses.
Why does the label say this product contains a Turkey Tails fruiting body extract I can't check for interactions?
The extract itself is made of component ingredients that we could check individually, but the product label doesn't break those out separately — it just lists the extract as a whole. Your best move is to check your specific medications with the search tool on this page.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Turkey Tail Mushroom is safe with your meds?

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Turkey Tail Mushroom label
Go deeper

The Full Monographs Behind Turkey Tail Mushroom’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Beta-glucans

Interacts with 293 drugs

Beta-glucans are natural fibers found in oats, barley, mushrooms, and yeast. The strongest evidence supports the oat and barley types for modestly lowering cholesterol and blood sugar, while...

Read the full Beta-glucans monograph →
Sources

Sources & How We Checked

Turkey Tail Mushroom's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 11 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Beta-glucans 11 references
  1. Katz, D. L., Nawaz, H., Boukhalil, J., Giannamore, V., Chan, W., Ahmadi, R., and Sarrel, P. M. Acute effects of oats and vitamin E on endothelial responses to ingested fat. Am.J.Prev.Med. 2001;20(2):124-129. PubMed
  2. Keenan, J. M., Pins, J. J., Frazel, C., Moran, A., and Turnquist, L. Oat ingestion reduces systolic and diastolic blood pressure in patients with mild or borderline hypertension: a pilot trial. J.Fam.Pract. 2002;51(4):369.
  3. Maki, K. C., Galant, R., Samuel, P., Tesser, J., Witchger, M. S., Ribaya-Mercado, J. D., Blumberg, J. B., and Geohas, J. Effects of consuming foods containing oat beta-glucan on blood pressure, carbohydrate metabolism and biomarkers of oxidative stress i
  4. Bergendiova, K., Tibenska, E., and Majtan, J. Pleuran (beta-glucan from Pleurotus ostreatus) supplementation, cellular immune response and respiratory tract infections in athletes. Eur.J.Appl.Physiol 2011;111(9):2033-2040.
  5. Talbott S, Talbott J. Effect of beta 1,3/1,6 glucan on respiratory tract infection symptoms and mood state in marathon athletes. J Sports Sci Med 2009;8(4):509-515.
  6. Feldman S, Schwartz HI Kalman DS Mayers A Kohrman HM Clemens R Krieger DR. Randomized phase II clinical trials of Wellmune WGP® for immune support during cold and flu season. The Journal of Applied Research 2009;9(1-2):30-42.
  7. McFarlin BK, Carpenter KC, Davidson T, McFarlin MA. Baker's yeast beta glucan supplementation increases salivary IgA and decreases cold/flu symptomatic days after intense exercise. J Diet Suppl. 2013;10(3):171-83. PubMed
  8. Jesenak M, Urbancek S, Majtan J, Banovcin P, Hercogova J. ß-Glucan-based cream (containing pleuran isolated from pleurotus ostreatus) in supportive treatment of mild-to-moderate atopic dermatitis. J Dermatolog Treat 2016;27(4):351-4.
  9. Mah E, Kaden VN, Kelley KM, Liska DJ. Beverage containing dispersible yeast ß-glucan decreases cold/flu symptomatic days after intense exercise: a randomized controlled trial. J Diet Suppl 2020;17(2):200-10. PubMed
  10. Zhong K, Liu Z, Lu Y, Xu X. Effects of yeast ß-glucans for the prevention and treatment of upper respiratory tract infection in healthy subjects: a systematic review and meta-analysis. Eur J Nutr. 2021. PubMed
  11. Cardenas FI, Mauguen A, Cheung IY, et al. Phase I trial of oral yeast-derived ß-glucan to enhance anti-GD2 immunotherapy of resistant high-risk neuroblastoma. Cancers (Basel) 2021;13(24):6265. PubMed

See these in context on the Beta-glucans monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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