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Dietary supplement

Turkey Tail Mushroom Ingredients & Drug Interactions

by Gaia Herbs

Turkey Tail Mushroom label
See full label image
Capsule Category: Botanical
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 16, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Turkey Tail Mushroom against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Turkey Tail Mushroom is a dietary supplement by Gaia Herbs with 1 active ingredient. Its ingredients are commonly taken for high cholesterol, heart health, immune support.Based on those ingredients, 293 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Beta Glucans. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

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Check Your Meds Against Turkey Tail Mushroom by Gaia Herbs

Ask about any prescription or over-the-counter medication and we check it for interactions with Turkey Tail Mushroom by Gaia Herbs — and tell you which ingredient is responsible.

Pharmacist-reviewed data Checks every ingredient Answer in seconds
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HelloPharmacist Scorecard of Turkey Tail Mushroom by Gaia Herbs

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Sep 17, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • “Turkey Tails fruiting body Extract” is listed as a grouped ingredient — the label gives one combined amount (400 mg) without saying how much of each component you get.

Turkey Tail Mushroom by Gaia Herbs contains one active ingredient: beta-glucans from the Turkey Tails fruiting body extract. Beta-glucans are fiber-like compounds found in mushroom cell walls that your immune system and digestive system recognize and respond to.

The product also contains pullulan, an inactive ingredient used as a capsule filler.

Does it work?

Not established
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not established

The graded evidence we hold for these ingredients covers different conditions than the ones this product is marketed for, so there's no established rating for its stated use — see Beta-glucans's own graded uses on its monograph.

Why this rating?
  • The label markets this product for: Immune and liver support.
  • We looked for evidence on: Aging, Allergic rhinitis (hay fever), Atopic dermatitis (eczema), Chronic fatigue syndrome (CFS), Critical illness (trauma), Exercise-induced respiratory infections — and 4 related terms.
  • The closest evidence on file: Beta-glucans is rated "Insufficient Reliable Evidence To Rate" for Allergic rhinitis (hay fever) (Natural Medicines).
  • Also on file: Beta-glucans is rated "Insufficient Reliable Evidence To Rate" for Chronic fatigue syndrome (CFS), Inflammatory bowel disease (IBD), Atopic dermatitis (eczema), Exercise-induced respiratory infections, and more.

Beta-glucans are rated Likely Effective for dyslipidemia (high cholesterol) and coronary heart disease. The evidence supports their use for these cardiovascular and lipid-related concerns.

We hold no effectiveness data for Turkey Tail Mushroom against other conditions.

The evidence, ingredient by ingredient Beta-glucans

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Beta-glucans from food sources are generally well tolerated by most people. Concentrated supplements, however, lack extensive safety data, so caution is warranted when using them at higher doses than you'd get from eating mushrooms.

Most common side effects are limited to topical use (skin reactions and contact dermatitis when applied to the skin). One trial participant on a very high oral dose developed temporary elevations in liver enzymes within five days, though this was rare.

There isn't enough data on concentrated beta-glucans during breastfeeding to know either way — talk with your doctor or pharmacist for personalized advice if you're nursing.

Side effects, ingredient by ingredient Beta-glucans

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Beta-glucans.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: immunosuppressants / transplant drugs.
  • For scale: 293 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before taking this product, check with your doctor or pharmacist if you're on blood pressure medication or immunosuppressants (drugs that weaken your immune response, often used after transplant or for autoimmune conditions). Beta-glucans may lower blood pressure further or interfere with immune-suppressing therapy — both Moderate concerns worth clarifying with your prescriber.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with no established evidence rating for its marketed use. Moderate medication interactions have been identified, and safety information is well characterized.

Turkey Tail Mushroom is a reasonable choice if you're looking to support cholesterol or heart health — the evidence for beta-glucans in those areas is solid. If you take blood pressure medication or immunosuppressants, check with your doctor or pharmacist before starting, since the beta-glucans could affect how those drugs work.

Your healthcare provider can weigh the benefit against the risk for your situation.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Sep 22, 2022.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Turkey Tail Mushroom, straight from the product label.

Brand Gaia Herbs
Net contents 40 Vegan Capsule(s)
Market status On market
Date entered into DSLD Sep 22, 2022
DSLD ID 273407
Product type Botanical
Supplement form Capsule
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years), Women (not pregnant or lactating), Organic, Gluten Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Turkey Tail Mushroom by Gaia Herbs, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Capsule(s)
Maximum serving Sizes:
1 Capsule(s)
Servings per container
40
IngredientAmount% DV
Beta Glucans135 mg--
Turkey Tails fruiting body Extract400 mg--

Other ingredients: Pullulan

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Brand IP Statement(s)

Gaia Herbs EST 1987

Formulation

Immune & liver support

6X strength

Non GMO Project Verified nongmoproject.org

Certified Organic by Oregon Tilth.

Natural separation may occur. This does not affect product quality.

No grain & rice fillers Gluten free

Sustainably sourced Guaranteed beta glucan levels

Formula

Only fruiting body extracts Made with organic mushrooms

The Gaia Difference Organic mushrooms Only fruiting bodies

Why Fruiting Bodies? We use only the fruiting bodies of mushrooms, as the concentration of active beneficial compounds like beta glucans is greatest in this part vs. the mycelium.

Seals/Symbols

Non GMO Project Verified nongmoproject.org

Certified B Corporation

Suggested/Recommended/Usage/Directions

One A Day

Suggested Use Adults take 1 capsule once daily. Benefits build over time.

FDA Statement of Identity

Herbal Supplement

Precautions

Warning: Reproductive Harm-www.P65Warnings.ca.gov/food

Not for use during pregnancy or lactation. If you have a medical condition or take medications, please consult with your doctor before use.

Store away from children.

Use only as directed on label. Safety-sealed for your protection.

Storage

Keep bottle capped at all times and store in a cool, dry place.

General Statements

Gaia Herbs delivers unprecedented traceability by screening every product and sharing the results online. To learn more, enter the unique ID # below at meetyourherbs.com.

Discover our guiding truths at: Facebook Instagram @gaiaherbs

Fruiting Body - Cap Gills Stem Mycelium

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Turkey Tail Mushroom by Gaia Herbs label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Turkey Tail Mushroom label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Turkey Tail Mushroom by Gaia Herbs

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size1 Capsule(s) Dosage formCapsule Servings per container40 Amounts shown are per serving.

Turkey Tails fruiting body Extract

400 mg per serving

Other (inactive) ingredients: Pullulan. These complete the product’s ingredient list but are not active constituents.

Interaction report

Turkey Tail Mushroom by Gaia Herbs Drug Interactions

Want to check YOUR meds against Turkey Tail Mushroom?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
293Drugs
293 Moderate

Ingredients driving the most interactions

Beta Glucans 293

Individual Drug Interactions

The ingredients in Turkey Tail Mushroom interact with 293 drugs. Click any drug to see the details.

1 of the 1 ingredient in Turkey Tail Mushroom interact with drugs. Each result below shows which ingredient is responsible. Beta Glucans

Each ingredient & the kinds of drugs it affects

For each ingredient in Turkey Tail Mushroom with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Beta Glucans2 drug types · 293 drugs

Antihypertensive Drugs

Theoretically, taking beta-glucans with antihypertensive drugs might increase the risk of hypotension.
Clinical research shows that taking beta-glucans may reduce systolic and diastolic blood pressure in some hypertensive individuals.

Likelihood Possible Evidence D
Immunosuppressants

Theoretically, beta-glucans might interfere with immunosuppressive therapy.
Some clinical research shows that beta-glucans have immunostimulant effects.

Likelihood Possible Evidence D
Beta Glucans full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Turkey Tail Mushroom, from the product label.

Gaia Herbs

See all Gaia Herbs products
Name
Gaia Herbs, Inc.
Street Address
101 Gaia Herbs Drive
City
Brevard
State
NC
ZipCode
28712
Web Address
www.gaiaherbs.com
Pharmacist Counseling Corner

Turkey Tail Mushroom by Gaia Herbs: Common Questions

Does Turkey Tail Mushroom by Gaia Herbs interact with any medications?
Yes. Based on its ingredients, Turkey Tail Mushroom has a known interaction with 293 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Turkey Tail Mushroom contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Does Turkey Tail Mushroom actually work?
For high cholesterol (dyslipidemia) and heart disease, yes — beta-glucans are rated Likely Effective based on clinical evidence. For other uses, we don't have effectiveness data on file.
Are there side effects?
Beta-glucans are generally well tolerated. When applied to skin, some people develop mild contact dermatitis or skin reactions. Oral use is rare to cause side effects, though one trial participant on a very high dose had temporary liver enzyme changes. Most people do fine with it.
Can I take this while breastfeeding?
There isn't enough research on concentrated supplement doses during breastfeeding to know either way. Talk with your doctor or pharmacist — they know your situation and can help you decide.
What exactly is in this capsule?
The active ingredient is beta-glucans from Turkey Tails mushroom fruiting body. The capsule itself is made of pullulan, an inactive filler.
Why would this interact with blood pressure medication?
Beta-glucans can lower blood pressure on their own. Combined with medication that already lowers it, your blood pressure could drop too far — that's why your doctor should know before you add it.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Turkey Tail Mushroom is safe with your meds?

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Turkey Tail Mushroom label
Go deeper

The Full Monographs Behind Turkey Tail Mushroom’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Beta-glucans

Interacts with 293 drugs

Beta-glucans are natural fibers found in oats, barley, mushrooms, and yeast. The strongest evidence supports the oat and barley types for modestly lowering cholesterol and blood sugar, while...

Read the full Beta-glucans monograph →
Sources

Sources & How We Checked

Turkey Tail Mushroom's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 11 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Beta-glucans 11 references
  1. Katz, D. L., Nawaz, H., Boukhalil, J., Giannamore, V., Chan, W., Ahmadi, R., and Sarrel, P. M. Acute effects of oats and vitamin E on endothelial responses to ingested fat. Am.J.Prev.Med. 2001;20(2):124-129. PubMed
  2. Keenan, J. M., Pins, J. J., Frazel, C., Moran, A., and Turnquist, L. Oat ingestion reduces systolic and diastolic blood pressure in patients with mild or borderline hypertension: a pilot trial. J.Fam.Pract. 2002;51(4):369.
  3. Maki, K. C., Galant, R., Samuel, P., Tesser, J., Witchger, M. S., Ribaya-Mercado, J. D., Blumberg, J. B., and Geohas, J. Effects of consuming foods containing oat beta-glucan on blood pressure, carbohydrate metabolism and biomarkers of oxidative stress i
  4. Bergendiova, K., Tibenska, E., and Majtan, J. Pleuran (beta-glucan from Pleurotus ostreatus) supplementation, cellular immune response and respiratory tract infections in athletes. Eur.J.Appl.Physiol 2011;111(9):2033-2040.
  5. Talbott S, Talbott J. Effect of beta 1,3/1,6 glucan on respiratory tract infection symptoms and mood state in marathon athletes. J Sports Sci Med 2009;8(4):509-515.
  6. Feldman S, Schwartz HI Kalman DS Mayers A Kohrman HM Clemens R Krieger DR. Randomized phase II clinical trials of Wellmune WGP® for immune support during cold and flu season. The Journal of Applied Research 2009;9(1-2):30-42.
  7. McFarlin BK, Carpenter KC, Davidson T, McFarlin MA. Baker's yeast beta glucan supplementation increases salivary IgA and decreases cold/flu symptomatic days after intense exercise. J Diet Suppl. 2013;10(3):171-83. PubMed
  8. Jesenak M, Urbancek S, Majtan J, Banovcin P, Hercogova J. ß-Glucan-based cream (containing pleuran isolated from pleurotus ostreatus) in supportive treatment of mild-to-moderate atopic dermatitis. J Dermatolog Treat 2016;27(4):351-4.
  9. Mah E, Kaden VN, Kelley KM, Liska DJ. Beverage containing dispersible yeast ß-glucan decreases cold/flu symptomatic days after intense exercise: a randomized controlled trial. J Diet Suppl 2020;17(2):200-10. PubMed
  10. Zhong K, Liu Z, Lu Y, Xu X. Effects of yeast ß-glucans for the prevention and treatment of upper respiratory tract infection in healthy subjects: a systematic review and meta-analysis. Eur J Nutr. 2021. PubMed
  11. Cardenas FI, Mauguen A, Cheung IY, et al. Phase I trial of oral yeast-derived ß-glucan to enhance anti-GD2 immunotherapy of resistant high-risk neuroblastoma. Cancers (Basel) 2021;13(24):6265. PubMed

See these in context on the Beta-glucans monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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