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Dietary supplement

Cordyceps-M Powder Ingredients & Drug Interactions

by Real Mushrooms

Powder Category: Botanical
Most serious interaction: Moderate
The interaction bottom line Most serious interaction: Moderate

Cordyceps-M Powder is a dietary supplement by Real Mushrooms with 1 active ingredient. Its ingredients are commonly taken for fatigue and low energy, athletic performance and stamina, respiratory and lung support.Based on those ingredients, 416 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Cordyceps Mushroom Extract. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

HelloPharmacist Scorecard of Cordyceps-M Powder by Real Mushrooms

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • “Cordyceps Mushroom Extract” is listed as a grouped ingredient — the label gives one combined amount (1,000 mg) without saying how much of each component you get.

Cordyceps-M Powder is a single-ingredient product: beta-glucans derived from mushroom sources. Beta-glucans are complex carbohydrates found in the cell walls of fungi and are the active compound responsible for the supplement's effects.

The product contains no inactive ingredients listed.

Does it work?

Not established
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not established

The graded evidence we hold for these ingredients covers different conditions than the ones this product is marketed for, so there's no established rating for its stated use — see Beta-glucans's own graded uses on its monograph.

Why this rating?
  • The label markets this product for: peak performance and energy.
  • We looked for evidence on: Athletic performance, Fatigue, Chronic fatigue syndrome (CFS), stamina, endurance, vitality.
  • The closest evidence on file: Beta-glucans is rated "Insufficient Reliable Evidence To Rate" for Chronic fatigue syndrome (CFS) (Natural Medicines).

Beta-glucans in this product are likely effective for lowering cholesterol (dyslipidemia) and supporting heart health in coronary heart disease (CHD). These ratings are based on clinical evidence.

Keep in mind that 'likely effective' means there's good research backing it, but individual results can vary.

The evidence, ingredient by ingredient Cordyceps Beta-glucans

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Beta-glucans from food sources are generally well tolerated. However, concentrated supplement doses lack the long-term safety data that food amounts have, so it's wise to use caution.

In clinical trials, oral beta-glucans were well tolerated overall, though one child in a high-dose trial showed temporary liver enzyme elevations. When applied to skin, some people have reported mild contact dermatitis or skin reactions; these were typically mild and resolved on their own.

There isn't enough research on concentrated supplement doses during breastfeeding to know whether they're safe, so talk with your doctor or pharmacist for personalized advice if you're nursing.

Side effects, ingredient by ingredient Cordyceps Beta-glucans

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Beta-glucans.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: immunosuppressants / transplant drugs.
  • For scale: 293 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before taking this supplement, double-check with your doctor or pharmacist if you're on any blood pressure medication (antihypertensives) — beta-glucans may lower your blood pressure further. Also check if you take any immunosuppressant drugs, since beta-glucans may interfere with how they work.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with no established evidence rating for its marketed use. Moderate medication interactions have been identified, and safety information is well characterized.

Cordyceps-M Powder may be worth considering if you're looking to support cholesterol and heart health and you don't take blood pressure medication or immunosuppressant drugs. If you do take either of those types, check with your doctor or pharmacist first — the interaction risk is real.

Talk it over with your own healthcare provider before starting to make sure it fits your situation.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Apr 23, 2024.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Cordyceps-M Powder, straight from the product label.

Brand Real Mushrooms
Barcode (UPC) 627843438748
Net contents 2.12 Ounce(s); 60 Gram(s)
Market status On market
Date entered into DSLD Apr 23, 2024
DSLD ID 312720
Product type Botanical
Supplement form Powder
Dietary claims / uses Nutrient, All Other, Structure/Function
Intended target group(s) Vegan, Vegetarian, Adult (18 - 50 Years), Organic, Gluten Free, Dairy Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Cordyceps-M Powder by Real Mushrooms, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Gram(s)
Maximum serving Sizes:
1 Gram(s)
Servings per container
60
UPC/BARCODE
627843438748
IngredientAmount% DV
Beta-1,3-1,6-Glucan250 mg--
Cordyceps Mushroom Extract1000 mg--

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Formulation

100% pure + organic

100% pure + organic Peak performance Quality grown Bulk powder

Scientifically verified for active compounds

No grain No starch No fillers

Vegan

Non-GMO Gluten free

Certified organic and sustainably produced

Our guarantee: This product is scientifically verified for active compounds.

There are no added fillers, starch, grains or mycelium.

Certified Organic by Quality Assurance International

Formula

Organic mushroom extract powder

Our quality commitment to you Extracts are made from 100% pure cordyceps mushrooms Guaranteed potency: Greater than 25% beta-glucans

Cordyceps militaris mushroom

Seals/Symbols

USDA Organic

USDA Organic Vegan Quality Assurance International Certified Organic

FDA Statement of Identity

Dietary Supplement

General Statements

Purity. Potency. History. Get deals become a VIP customer realmushrooms.com/VIP

NPN# 80093955

Suggested/Recommended/Usage/Directions

Great with tea, coffee & smoothies

Suggested use: Adults take 1 gram per day.

Storage

Storage: Store in a cool dry place with zip lock securely closed.

Precautions

Warning: Keep out of reach of children.

Consult a physician if you are pregnant or nursing; have or had a medical condition; or are taking prescription drugs.

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

See for yourself

Cordyceps-M Powder by Real Mushrooms label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

What’s inside

The Ingredients in Cordyceps-M Powder by Real Mushrooms

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size1 Gram(s) Dosage formPowder Servings per container60 Amounts shown are per serving.

Cordyceps Mushroom Extract

Interacts with
249 drugs
1000 mg per serving Form: Cordyceps militaris Extract

Cordyceps is a fungus used in traditional Chinese medicine for energy, exercise performance, and lung and immune support. Human research is limited an...

Cordyceps Mushroom Extract monograph & interactions
Interaction report

Cordyceps-M Powder by Real Mushrooms Drug Interactions

Want to check YOUR meds against Cordyceps-M Powder?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

Go to the checker
416Drugs
408 Moderate 8 Minor

Ingredients driving the most interactions

Each ingredient & the kinds of drugs it affects

For each ingredient in Cordyceps-M Powder with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Cordyceps Mushroom Extract3 drug types · 249 drugs

Anticoagulant/Antiplatelet Drugs

Theoretically, cordyceps may increase the risk of bleeding when used with antiplatelet or anticoagulant drugs.
In vitro and animal research suggests that cordyceps extract inhibits platelet aggregation and function. However, this interaction has not been reported in humans.

Likelihood Possible Evidence D
Immunosuppressants

Theoretically, concurrent use of cordyceps might interfere with immunosuppressive therapy.
Animal and in vitro research suggests that cordyceps stimulates the immune system. However, limited clinical research suggests that taking cordyceps may lower the necessary therapeutic dose of the immunosuppressant cyclosporine, which suggests that cordyceps may have an immunosuppressive effect.

Likelihood Possible Evidence B
Testosterone

Theoretically, concurrent use of cordyceps and testosterone might have additive effects.
Animal research suggests that cordyceps can increase testosterone levels. The clinical significance of this finding is unclear.

Likelihood Possible Evidence D
The maker

Brand information

Manufacturer and brand details for Cordyceps-M Powder, from the product label.

Real Mushrooms

See all Real Mushrooms products
Name
Real Mushrooms Inc.
Street Address
908 17 Ave SW, Suite 303
City
Calgary
ZipCode
AB T2T 0A3
Phone Number
1-800-263-4387
Web Address
realmushrooms.com
Pharmacist Counseling Corner

Cordyceps-M Powder by Real Mushrooms: Common Questions

Does Cordyceps-M Powder by Real Mushrooms interact with any medications?
Yes. Based on its ingredients, Cordyceps-M Powder has a known interaction with 416 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Cordyceps-M Powder contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
What is this supplement actually made from?
Cordyceps-M Powder contains beta-glucans, which are beneficial carbohydrates extracted from mushrooms. Beta-glucans are the active part of the supplement that gives it its health-supporting effects.
Does it really help with cholesterol and heart health?
Yes — beta-glucans are likely effective for both lowering cholesterol (dyslipidemia) and supporting heart health in coronary heart disease based on clinical research. That said, results can vary from person to person.
Are there common side effects I should know about?
Taken by mouth, beta-glucans are generally well tolerated with no major side effects reported in most people. If applied to skin, some people have reported mild skin irritation or contact dermatitis, though these usually resolve on their own.
Is it safe to take while breastfeeding?
There isn't enough research on concentrated supplement doses during breastfeeding to say for sure. Talk with your doctor or pharmacist about whether it's right for you while nursing — they can weigh your personal situation.
Is this just cordyceps mushroom, or is there more to it?
The product contains beta-glucans as the active ingredient. It also lists Cordyceps Mushroom Extract, but the specific components of that extract aren't detailed on file.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Cordyceps-M Powder is safe with your meds?

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Cordyceps-M Powder label
Sources

Sources & How We Checked

Cordyceps-M Powder's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 25 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Beta-glucans 11 references
  1. Katz, D. L., Nawaz, H., Boukhalil, J., Giannamore, V., Chan, W., Ahmadi, R., and Sarrel, P. M. Acute effects of oats and vitamin E on endothelial responses to ingested fat. Am.J.Prev.Med. 2001;20(2):124-129. PubMed
  2. Keenan, J. M., Pins, J. J., Frazel, C., Moran, A., and Turnquist, L. Oat ingestion reduces systolic and diastolic blood pressure in patients with mild or borderline hypertension: a pilot trial. J.Fam.Pract. 2002;51(4):369.
  3. Maki, K. C., Galant, R., Samuel, P., Tesser, J., Witchger, M. S., Ribaya-Mercado, J. D., Blumberg, J. B., and Geohas, J. Effects of consuming foods containing oat beta-glucan on blood pressure, carbohydrate metabolism and biomarkers of oxidative stress i
  4. Bergendiova, K., Tibenska, E., and Majtan, J. Pleuran (beta-glucan from Pleurotus ostreatus) supplementation, cellular immune response and respiratory tract infections in athletes. Eur.J.Appl.Physiol 2011;111(9):2033-2040.
  5. Talbott S, Talbott J. Effect of beta 1,3/1,6 glucan on respiratory tract infection symptoms and mood state in marathon athletes. J Sports Sci Med 2009;8(4):509-515.
  6. Feldman S, Schwartz HI Kalman DS Mayers A Kohrman HM Clemens R Krieger DR. Randomized phase II clinical trials of Wellmune WGP® for immune support during cold and flu season. The Journal of Applied Research 2009;9(1-2):30-42.
  7. McFarlin BK, Carpenter KC, Davidson T, McFarlin MA. Baker's yeast beta glucan supplementation increases salivary IgA and decreases cold/flu symptomatic days after intense exercise. J Diet Suppl. 2013;10(3):171-83. PubMed
  8. Jesenak M, Urbancek S, Majtan J, Banovcin P, Hercogova J. ß-Glucan-based cream (containing pleuran isolated from pleurotus ostreatus) in supportive treatment of mild-to-moderate atopic dermatitis. J Dermatolog Treat 2016;27(4):351-4.
  9. Mah E, Kaden VN, Kelley KM, Liska DJ. Beverage containing dispersible yeast ß-glucan decreases cold/flu symptomatic days after intense exercise: a randomized controlled trial. J Diet Suppl 2020;17(2):200-10. PubMed
  10. Zhong K, Liu Z, Lu Y, Xu X. Effects of yeast ß-glucans for the prevention and treatment of upper respiratory tract infection in healthy subjects: a systematic review and meta-analysis. Eur J Nutr. 2021. PubMed
  11. Cardenas FI, Mauguen A, Cheung IY, et al. Phase I trial of oral yeast-derived ß-glucan to enhance anti-GD2 immunotherapy of resistant high-risk neuroblastoma. Cancers (Basel) 2021;13(24):6265. PubMed

See these in context on the Beta-glucans monograph →

Cordyceps 14 references
  1. Zhu JS, Halpern GM, Jones K. The scientific rediscovery of an ancient Chinese herbal medicine: Cordyceps sinensis: part I. J Altern Complement Med 1998;4:289-303.
  2. Zhu JS, Halpern GM, Jones K. The scientific rediscovery of a precious ancient Chinese herbal regimen: Cordyceps sinensis: part II. J Altern Complement Med 1998;4:429-57.
  3. Chen YJ, Shiao MS, Lee SS, Wang SY. Effect of Cordyceps sinensis on the proliferation and differentiation of human leukemic U937 cells. Life Sci 1997;60:2349-59. PubMed
  4. Zhao Y. [Inhibitory effects of alcoholic extract of Cordyceps sinensis on abdominal aortic thrombus formation in rabbits]. Chung Hua I Hsueh Tsa Chih (Taipei) 1991;71:612-5, 42.
  5. Chen GZ, Chen GL, Sun T, et al. Effects of Cordyceps sinensis on murine T lymphocyte subsets. Chin Med J (English) 1991;104:4-8.
  6. Zhu XY, Yu HY. [Immunosuppressive effect of cultured Cordyceps sinensis on cellular immune response]. Chung Hsi I Chieh Ho Tsa Chih 1990;10:485-7, 454.
  7. Hsu, C. C., Huang, Y. L., Tsai, S. J., Sheu, C. C., and Huang, B. M. In vivo and in vitro stimulatory effects of Cordyceps sinensis on testosterone production in mouse Leydig cells. Life Sci 9-5-2003;73(16):2127-2136. PubMed
  8. Ikumoto, T., Sasaki, S., Namba, H., Toyama, R., Moritoki, H., and Mouri, T. [Physiologically active compounds in the extracts from tochukaso and cultured mycelia of Cordyceps and Isaria]. Yakugaku Zasshi 1991;111(9):504-509. PubMed
  9. Wu, T. N., Yang, K. C., Wang, C. M., Lai, J. S., Ko, K. N., Chang, P. Y., and Liou, S. H. Lead poisoning caused by contaminated Cordyceps, a Chinese herbal medicine: two case reports. Sci.Total Environ. 4-5-1996;182(1-3):193-195. PubMed
  10. Hong T, Zhang M, Fan J. Cordyceps sinensis (a traditional Chinese medicine) for kidney transplant recipients (Review). Cochrane Database Syst Rev. 2015;(10):CD009698. doi: 10.1002/14651858.CD009698.pub2.
  11. Zhang HW, Lin ZX, Tung YS, Kwan TH, Mok CK, Leung C, Chan LS. Cordyceps sinensis (a traditional Chinese medicine) for treating chronic kidney disease (Review). Cochrane Database Syst Rev. 2014;(12):CD008353. doi: 10.1002/14651858.CD008353.pub2. PubMed
  12. Bee Yean O, Zoriah A. Efficacy of Cordyceps sinensis as an adjunctive treatment in hemodialysis patients: a systematic review and Meta-analysis. J Tradit Chin Med. 2019;39(1):1-14.
  13. Thurian D, Montani M, Stickel F. Drug-induced, mixed-type hepatitis following ingestion of Cordyceps sinensis. Int J Clin Pharmacol Ther 2022;60(2):115-120. PubMed
  14. Yu X, Mao Y, Shergis JL, et al. Effectiveness and safety of oral Cordyceps sinensis on stable COPD of GOLD stages 2-3: Systematic review and meta-analysis. Evid Based Complement Alternat Med. 2019;2019:4903671.

See these in context on the Cordyceps monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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