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Dietary supplement

Tremella Powder Ingredients & Drug Interactions

by Real Mushrooms

Powder Category: Botanical
Most serious interaction: Moderate
The interaction bottom line Most serious interaction: Moderate

Tremella Powder is a dietary supplement by Real Mushrooms with 1 active ingredient. Its ingredients are commonly taken for high cholesterol, heart health, immune support.Based on those ingredients, 293 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Beta-(1,3)(1,6)-Glucans. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

HelloPharmacist Scorecard of Tremella Powder by Real Mushrooms

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • “Tremella Mushroom Extract” is listed as a grouped ingredient — the label gives one combined amount (1,000 mg) without saying how much of each component you get.

Tremella Powder contains one active ingredient: Tremella Mushroom Extract, supplied as a blend containing beta-glucans. The extract form is more concentrated than whole mushroom, so you're getting a stronger dose of the active compounds than you'd get from eating tremella fresh.

There are no other inactive ingredients (fillers, binders, or capsule materials) listed for this product.

Does it work?

Not established
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not established

The graded evidence we hold for these ingredients covers different conditions than the ones this product is marketed for, so there's no established rating for its stated use — see Beta-glucans's own graded uses on its monograph.

Why this rating?
  • The label markets this product for: Immune support and general health.
  • We looked for evidence on: Lower respiratory tract infections, Upper respiratory tract infection (URTI), Exercise-induced respiratory infections, Wound healing, Immune function, Overall wellness.
  • The closest evidence on file: Beta-glucans is rated "Insufficient Reliable Evidence To Rate" for Lower respiratory tract infections (Natural Medicines).
  • Also on file: Beta-glucans is rated "Insufficient Reliable Evidence To Rate" for Exercise-induced respiratory infections, Wound healing.

Beta-glucans in this product are rated Likely Effective for dyslipidemia (abnormal cholesterol and fat levels) and coronary heart disease. The evidence supports their use for heart health and lipid management.

We have no effectiveness data on file for the Tremella Mushroom Extract itself when separated from its beta-glucan content.

The evidence, ingredient by ingredient Beta-glucans

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Beta-glucans from food sources are generally well tolerated by most people. However, concentrated supplements like this powder lack the safety data that whole foods have, so use caution — the dose and form here are different from eating tremella in your diet.

Pregnancy and lactation: we don't hold safety information for this ingredient during pregnancy or breastfeeding. There is little research on supplement doses in these periods, so talk with your doctor or pharmacist before using this product if you're pregnant or nursing.

Side effects, ingredient by ingredient Beta-glucans

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Beta-glucans.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: immunosuppressants / transplant drugs.
  • For scale: 293 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Check your exact medications against our search tool before starting. Two drug types have documented interactions: blood pressure medications (Moderate risk of overly low blood pressure) and immune-suppressing drugs (Moderate risk of reduced effectiveness).

If you take either type, a conversation with your pharmacist is a must.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with no established evidence rating for its marketed use. Moderate medication interactions have been identified, and safety information is well characterized.

Tremella Powder is most suitable for people interested in supporting heart health and cholesterol levels who don't take blood pressure medications or immune-suppressing drugs. If you're on either of those drug types, check your specific medications with our tool before starting.

Always run your full medication list past your pharmacist first.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Feb 23, 2025.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Tremella Powder, straight from the product label.

Brand Real Mushrooms
Barcode (UPC) 628110068873
Net contents 150 Gram(s); 5.29 Ounce(s)
Market status On market
Date entered into DSLD Feb 23, 2025
DSLD ID 327056
Product type Botanical
Supplement form Powder
Dietary claims / uses Nutrient, All Other, Structure/Function
Intended target group(s) Vegan, Vegetarian, Adult (18 - 50 Years), Kosher, Organic, Gluten Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Tremella Powder by Real Mushrooms, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Gram(s)
Maximum serving Sizes:
1 Gram(s)
Servings per container
150
UPC/BARCODE
628110068873
IngredientAmount% DV
Tremella Mushroom Extract1000 mg--
Beta-(1,3)(1,6)-Glucans100 mg--

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Formulation

100% Pure + Organic USDA Organic

100% Pure + Organic Rejuvenation Quality grown Scientifically verified for active compounds Bulk powder

No grain No starch No fillers Non-GMO Gluten free

Vegan

Certified organic and sustainably produced

Our guarantee: This product is scientifically verified for active compounds.

There are no added fillers, starch, grains or mycelium.

Certified Organic by Quality Assurance International

Formula

Organic mushroom extract powder

Kosher

Our quality commitment to you Extracts are made from 100% pure tremella mushrooms Guaranteed potency: Greater than 10% beta-glucans

Tremella mushroom

Seals/Symbols

USDA Organic

USDA Organic Vegan Kosher Check Quality Assurance International Certified Organic

FDA Statement of Identity

Dietary Supplement

General Statements

Purity. Potency. History. Get Deals Become a VIP customer realmushrooms.com/VIP

NPN 80108855

Suggested/Recommended/Usage/Directions

Great with tea, coffee & smoothies

Suggested use: Adults take 1 gram per day.

Storage

Storage: Store in a cool dry place with zip lock securely closed.

Precautions

Warning: Keep out of reach of children.

Consult a physician if you are pregnant or nursing; have or had a medical condition; or are taking prescription drugs.

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

See for yourself

Tremella Powder by Real Mushrooms label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

What’s inside

The Ingredients in Tremella Powder by Real Mushrooms

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size1 Gram(s) Dosage formPowder Servings per container150 Amounts shown are per serving.

Tremella Mushroom Extract

1000 mg per serving
Interaction report

Tremella Powder by Real Mushrooms Drug Interactions

Want to check YOUR meds against Tremella Powder?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

Go to the checker
293Drugs
293 Moderate

Ingredients driving the most interactions

Each ingredient & the kinds of drugs it affects

For each ingredient in Tremella Powder with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Beta-(1,3)(1,6)-Glucans2 drug types · 293 drugs

Antihypertensive Drugs

Theoretically, taking beta-glucans with antihypertensive drugs might increase the risk of hypotension.
Clinical research shows that taking beta-glucans may reduce systolic and diastolic blood pressure in some hypertensive individuals.

Likelihood Possible Evidence D
Immunosuppressants

Theoretically, beta-glucans might interfere with immunosuppressive therapy.
Some clinical research shows that beta-glucans have immunostimulant effects.

Likelihood Possible Evidence D
The maker

Brand information

Manufacturer and brand details for Tremella Powder, from the product label.

Real Mushrooms

See all Real Mushrooms products
Name
Real Mushrooms Inc.
Street Address
908 17 Ave SW, Suite 303
City
Calgary
ZipCode
AB T2T 0A3
Phone Number
1-800-263-4387
Web Address
realmushrooms.com
Pharmacist Counseling Corner

Tremella Powder by Real Mushrooms: Common Questions

Does Tremella Powder by Real Mushrooms interact with any medications?
Yes. Based on its ingredients, Tremella Powder has a known interaction with 293 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Tremella Powder contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
What does this powder actually do?
It contains beta-glucans from tremella mushroom extract, which research supports for helping with cholesterol levels and coronary heart disease. The extract form is more concentrated than whole mushroom.
Is it safe if I'm on blood pressure medication?
Not without checking first. Beta-glucans can lower blood pressure, so taking them alongside blood pressure drugs raises the risk of your pressure dropping too low. Run your exact medication through our checker, then talk to your pharmacist.
Can I take this while breastfeeding?
We don't have safety data for concentrated beta-glucan supplements during breastfeeding. There isn't enough research to know either way, so talk with your doctor or pharmacist about whether it's right for you right now.
What are the side effects?
Beta-glucans are generally well tolerated when taken orally. One trial participant taking a very high dose developed mild, temporary liver enzyme elevations. Topical forms (creams) can cause skin reactions and contact dermatitis in some people, but you're taking this as a powder.
Does it have fillers or other ingredients I should know about?
No fillers, binders, or other inactive ingredients are listed for this product — it's just the tremella mushroom extract powder.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Tremella Powder is safe with your meds?

Our pharmacists answer your medication & supplement questions — free.

Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Tremella Powder label
Sources

Sources & How We Checked

Tremella Powder's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 11 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Beta-glucans 11 references
  1. Katz, D. L., Nawaz, H., Boukhalil, J., Giannamore, V., Chan, W., Ahmadi, R., and Sarrel, P. M. Acute effects of oats and vitamin E on endothelial responses to ingested fat. Am.J.Prev.Med. 2001;20(2):124-129. PubMed
  2. Keenan, J. M., Pins, J. J., Frazel, C., Moran, A., and Turnquist, L. Oat ingestion reduces systolic and diastolic blood pressure in patients with mild or borderline hypertension: a pilot trial. J.Fam.Pract. 2002;51(4):369.
  3. Maki, K. C., Galant, R., Samuel, P., Tesser, J., Witchger, M. S., Ribaya-Mercado, J. D., Blumberg, J. B., and Geohas, J. Effects of consuming foods containing oat beta-glucan on blood pressure, carbohydrate metabolism and biomarkers of oxidative stress i
  4. Bergendiova, K., Tibenska, E., and Majtan, J. Pleuran (beta-glucan from Pleurotus ostreatus) supplementation, cellular immune response and respiratory tract infections in athletes. Eur.J.Appl.Physiol 2011;111(9):2033-2040.
  5. Talbott S, Talbott J. Effect of beta 1,3/1,6 glucan on respiratory tract infection symptoms and mood state in marathon athletes. J Sports Sci Med 2009;8(4):509-515.
  6. Feldman S, Schwartz HI Kalman DS Mayers A Kohrman HM Clemens R Krieger DR. Randomized phase II clinical trials of Wellmune WGP® for immune support during cold and flu season. The Journal of Applied Research 2009;9(1-2):30-42.
  7. McFarlin BK, Carpenter KC, Davidson T, McFarlin MA. Baker's yeast beta glucan supplementation increases salivary IgA and decreases cold/flu symptomatic days after intense exercise. J Diet Suppl. 2013;10(3):171-83. PubMed
  8. Jesenak M, Urbancek S, Majtan J, Banovcin P, Hercogova J. ß-Glucan-based cream (containing pleuran isolated from pleurotus ostreatus) in supportive treatment of mild-to-moderate atopic dermatitis. J Dermatolog Treat 2016;27(4):351-4.
  9. Mah E, Kaden VN, Kelley KM, Liska DJ. Beverage containing dispersible yeast ß-glucan decreases cold/flu symptomatic days after intense exercise: a randomized controlled trial. J Diet Suppl 2020;17(2):200-10. PubMed
  10. Zhong K, Liu Z, Lu Y, Xu X. Effects of yeast ß-glucans for the prevention and treatment of upper respiratory tract infection in healthy subjects: a systematic review and meta-analysis. Eur J Nutr. 2021. PubMed
  11. Cardenas FI, Mauguen A, Cheung IY, et al. Phase I trial of oral yeast-derived ß-glucan to enhance anti-GD2 immunotherapy of resistant high-risk neuroblastoma. Cancers (Basel) 2021;13(24):6265. PubMed

See these in context on the Beta-glucans monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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