Interactions on record — worth a quick check against your medications. Based on 1 of 3 ingredients. Check your meds →
Dietary supplement

Soft Chews With Fiber Mixed Berry Ingredients & Drug Interactions

by GNC Probiotic

Soft Chews With Fiber Mixed Berry label
See full label image
Other (e.g. Tea Bag) Category: Non-nutrient/non-botanical
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 16, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Soft Chews With Fiber Mixed Berry against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Soft Chews With Fiber Mixed Berry is a dietary supplement by GNC Probiotic with 3 active ingredients. Its ingredients are commonly taken for constipation, irritable bowel syndrome (ibs), diarrhea.Based on those ingredients, 182 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Bacillus coagulans. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

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Check Your Meds Against Soft Chews With Fiber Mixed Berry by GNC Probiotic

Ask about any prescription or over-the-counter medication and we check it for interactions with Soft Chews With Fiber Mixed Berry by GNC Probiotic — and tell you which ingredient is responsible.

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HelloPharmacist Scorecard of Soft Chews With Fiber Mixed Berry by GNC Probiotic

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Jul 11, 2026

What’s inside

Partial disclosure
Ingredient Transparency · database check
Partial

Most active ingredients list an amount, but at least one is hidden in a blend or missing.

Why this rating?
  • The label discloses an exact amount for 1 of its 2 active ingredients.

This product has two active ingredients: Fiber and Bacillus coagulans, a probiotic strain. Bacillus coagulans is a live microorganism that colonizes your digestive tract; the fiber supports digestive function.

The inactive ingredients include a proprietary fiber blend, palm oil, soy lecithin, natural flavors, citric acid, malic acid, glycerin, fruit juice, vegetable juice, carrageenan, and sucralose — they help bind and flavor the chews.

Does it work?

Moderate evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Moderate

Some clinical evidence supports this product's ingredients for its stated purpose, but it isn't conclusive.

Why this rating?
  • The label markets this product for: Daily digestive and immune support.
  • We looked for evidence on: Constipation, Diarrhea, Dyspepsia, Flatulence, Irritable bowel syndrome (IBS), Antibiotic-associated diarrhea — and 4 related terms.
  • The strongest evidence on file: Bacillus Coagulans is rated "Possibly Effective" for Constipation (Natural Medicines).
  • Also on file: Bacillus Coagulans is rated "Possibly Effective" for Irritable bowel syndrome (IBS).
  • Also on file: Bacillus Coagulans is rated "Insufficient Reliable Evidence To Rate" for Antibiotic-associated diarrhea, Upper respiratory tract infection (URTI), Diarrhea, Dyspepsia, and more.

Bacillus coagulans is possibly effective for constipation and irritable bowel syndrome (IBS). For antibiotic-associated diarrhea, athletic performance, cancer, and nonalcoholic fatty liver disease, the evidence isn't strong enough to rate it as effective.

We hold no effectiveness data for the Fiber ingredient alone.

The evidence, ingredient by ingredient Bacillus Coagulans

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Bacillus coagulans is generally well tolerated in healthy adults, though the evidence and quality of probiotic products varies. There isn't enough reliable safety data overall, so talk with your doctor before using it.

A theoretical concern: since these products contain live organisms, there's some risk of infection in people with central catheters, severe illness, weakened immunity, or premature infants — but this risk is mainly in those groups, not in people with healthy immune systems and no catheters. No pregnancy or lactation data is on file for this product; discuss it with your doctor or pharmacist for personalized advice.

Side effects, ingredient by ingredient Bacillus Coagulans

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Bacillus Coagulans.
  • The most serious interaction on file is rated Moderate.
  • For scale: 182 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Antibiotics (Moderate severity) may reduce how well this probiotic works — separate them by a few hours. Check your exact medications with the tool on this page.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glancePartially disclosed formula with some supporting evidence for its stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.

This product may help with constipation or IBS symptoms. If you take antibiotics, separate them from the probiotic by a few hours.

Talk to your pharmacist before starting, especially if you have a weakened immune system, are severely ill, or use a central catheter.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 2 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Aug 22, 2017.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Soft Chews With Fiber Mixed Berry, straight from the product label.

Brand GNC Probiotic
Barcode (UPC) 048107173821
Net contents 30 Delicious Soft Chew(s)
Market status On market
Date entered into DSLD Aug 22, 2017
DSLD ID 76802
Product type Non-nutrient/non-botanical
Supplement form Other (e.g. Tea Bag)
Dietary claims / uses Nutrient, All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years), Gluten Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Soft Chews With Fiber Mixed Berry by GNC Probiotic, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Soft Chew(s)
Maximum serving Sizes:
1 Soft Chew(s)
UPC/BARCODE
048107173821
IngredientAmount% DV
Calories20 Calorie(s)--
Total Carbohydrates4 Gram(s)1%
Sugar1 Gram(s)--
Fiber2 Gram(s)8%
Bacillus coagulans0 NP--

Other ingredients: Proprietary Fiber Blend, Bacillus coagulans, Palm Oil, Soy Lecithin, Natural flavors, Citric Acid, Malic Acid, Glycerin, Fruit juice, Vegetable Juice, Carrageenan, Sucralose

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Formula

Soft chews with fiber

Daily probiotics support plus 2 g of fiber

5 billion CFUs of probiotics with 2 g of fiber per soft chew

Contains: Soybeans.

General Statements

Potency guaranteed

May provide digestive & immune support 5 billion CFUs Natural flavor

See dosing chart below. Dose Probiotics Fiber %Daily value Benefit 1-2 soft chews 5-10 billion CFUs 2-4 g 8-16% Daily digestive maintenance. 3-4 soft chews 15-20 billion CFUs 6-8 g 24-32% Support for regularly and digestive health. 5 soft chews 25 billion CFUs 10 g 40% Support for regularity, digestive health & satiety.

Why GNC Probiotic Soft Chews with Fiber?

Delicious taste Guaranteed potency through expiration date

FDA Statement of Identity

Dietary Supplement

General

CODE 256135 IRG

Suggested/Recommended/Usage/Directions

Directions: As a dietary supplement, take 1-5 soft chews daily.

Formulation

Gluten free Lactose free

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

Precautions

Contains: Soybeans.

Keep out of reach of children.

Brand IP Statement(s)

No artificial colors, no preservatives, sodium free, gluten free, lactose free, yeast free.

Seals/Symbols

GF Gluten free

Storage

Store in a cool, dry place.

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Soft Chews With Fiber Mixed Berry by GNC Probiotic label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Soft Chews With Fiber Mixed Berry label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Soft Chews With Fiber Mixed Berry by GNC Probiotic

These are the 3 active ingredients this product is made of. Select any to open its full monograph.

Serving size1 Soft Chew(s) Dosage formOther (e.g. Tea Bag) Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

Sugar

1 Gram(s) per serving

Fiber

2 Gram(s) per serving

Bacillus coagulans

Interacts with
182 drugs
0 NP per serving

Bacillus coagulans is a spore-forming probiotic that survives stomach acid well and may help with some digestive problems such as IBS, constipation, a...

Bacillus coagulans monograph & interactions

Other (inactive) ingredients: Proprietary Fiber Blend, Bacillus coagulans, Palm Oil, Soy Lecithin, Natural flavors, Citric Acid, Malic Acid, Glycerin, Fruit juice, Vegetable Juice, Carrageenan, Sucralose. These complete the product’s ingredient list but are not active constituents.

Interaction report

Soft Chews With Fiber Mixed Berry by GNC Probiotic Drug Interactions

Want to check YOUR meds against Soft Chews With Fiber Mixed Berry?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
182Drugs
182 Moderate

Ingredients driving the most interactions

Bacillus coagulans 182

Individual Drug Interactions

The ingredients in Soft Chews With Fiber Mixed Berry interact with 182 drugs. Click any drug to see the details.

1 of the 3 ingredients in Soft Chews With Fiber Mixed Berry interact with drugs. Each result below shows which ingredient is responsible. Bacillus coagulans

Each ingredient & the kinds of drugs it affects

For each ingredient in Soft Chews With Fiber Mixed Berry with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Bacillus coagulans1 drug type · 182 drugs

Antibiotic Drugs

Theoretically, taking antibiotics with Bacillus coagulans might decrease the effectiveness of B. coagulans.
B. coagulans preparations usually contain live and active organisms. Therefore, simultaneously taking antibiotics might kill a significant number of the organisms. Tell patients to separate administration of antibiotics and B. coagulans preparations by at least two hours.

Likelihood Probable Evidence D
Bacillus coagulans full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Soft Chews With Fiber Mixed Berry, from the product label.

GNC Probiotic

See all GNC Probiotic products
Name
General Nutrition Corporation
City
Pittsburgh
State
PA
ZipCode
15222
Phone Number
1-888-462-2548
Web Address
gnc.com
Pharmacist Counseling Corner

Soft Chews With Fiber Mixed Berry by GNC Probiotic: Common Questions

Does Soft Chews With Fiber Mixed Berry by GNC Probiotic interact with any medications?
Yes. Based on its ingredients, Soft Chews With Fiber Mixed Berry has a known interaction with 182 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Soft Chews With Fiber Mixed Berry contains 3 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Can I take this at the same time as my antibiotic?
No. Antibiotics can kill the live organisms in this probiotic and make it less effective. Take them a few hours apart — your pharmacist can help you schedule them.
Does this actually help with constipation?
Bacillus coagulans is possibly effective for constipation. That means some evidence suggests it may help, but it's not proven for everyone.
Is it safe for me if I have a weakened immune system?
There's a theoretical risk of infection from live probiotic organisms in people with severely weakened immunity or certain medical devices. Talk with your doctor first before using this product.
Can I take this while pregnant or breastfeeding?
We don't have enough safety data to say. Talk with your doctor or pharmacist — they can advise you based on your individual situation.
What does the Bacillus coagulans do?
It's a live probiotic strain that colonizes your gut to support digestive health, particularly for constipation and IBS symptoms.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Soft Chews With Fiber Mixed Berry is safe with your meds?

Our pharmacists answer your medication & supplement questions — free.

Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Soft Chews With Fiber Mixed Berry label
Go deeper

The Full Monographs Behind Soft Chews With Fiber Mixed Berry’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Bacillus Coagulans

Interacts with 182 drugs

Bacillus coagulans is a spore-forming probiotic that survives stomach acid well and may help with some digestive problems such as IBS, constipation, and certain types of diarrhea. The eviden...

Read the full Bacillus Coagulans monograph →
Sources

Sources & How We Checked

Soft Chews With Fiber Mixed Berry's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 20 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Bacillus Coagulans 20 references
  1. Saxelin M, Chuang NH, Chassy B, et al. Lactobacilli and bacteremia in southern Finland 1989-1992. Clin Infect Dis 1996;22:564-6. PubMed
  2. Tynkkynen S, Singh KV, Varmanen P. Vancomycin resistance factor of Lactobacillus rhamnosus GG in relation to enterococcal vancomycin resistance (van) genes. Int J Food Microbiol 1998;41:195-204. PubMed
  3. Klein G, Zill E, Schindler R, et al. Peritonitis associated with vancomycin-resistant Lactobacillus rhamnosus in a continuous ambulatory peritoneal dialysis patient; organism identification, antibiotic therapy, and case report. J Clin Microbiol 1998;36:
  4. Kalima P, Masterton RG, Roddie PH, et al. Lactobacillus rhamnosus infection in a child following bone marrow transplant. J Infect 1996;32:165-7. PubMed
  5. Goldin BR. Health Benefits of probiotics. Br J Nutr 1998;80:S203-7. DOI
  6. Rautio M, Jousimies-Somer H, Kauma H, et al. Liver abscess due to Lactobacillus rhamnosus strain indistinguishable from L. rhamnosus strain GG. Clin Infect Dis 1999;28:1159-60.
  7. MacGregor G, Smith AJ, Thakker B, Kinsella J. Yoghurt biotherapy: contraindicated in immunosuppressed patients? Postgrad Med J 2002;78:366-7. PubMed
  8. Land MH, Rouster-Stevens K, Woods CR, et al. Lactobacillus sepsis associated with probiotic therapy. Pediatrics 2005;115:178-81.
  9. De Groote MA, Frank DN, Dowell E, et al. Lactobacillus rhamnosus GG bacteremia associated with probiotic use in a child with short gut syndrome. Pediatr Infect Dis J 2005;24:278-80. PubMed
  10. Vahabnezhad E, Mochon AB, Wozniak LJ, Ziring DA. Lactobacillus bacteremia associated with probiotic use in a pediatric patient with ulcerative colitis. J Clin Gastroenterol. 2013;47(5):437-9. PubMed
  11. Pruccoli G, Silvestro E, Pace Napoleone C, Aidala E, Garazzino S, Scolfaro C. Are probiotics safe? Bifidobacterium bacteremia in a child with severe heart failure. Infez Med. 2019;27(2):175-178.
  12. Sendil S, Shrimanker I, Mansoora Q, Goldman J, Nookala VK. Lactobacillus rhamnosus bacteremia in an immunocompromised renal transplant patient. Cureus. 2020;12(2):e6887. PubMed
  13. Albarillo FS, Shah U, Joyce C, Slade D. Lactobacillus rhamnosus Infection: A single-center 4-year descriptive analysis. J Glob Infect Dis. 2020;12(3):119-123. PubMed
  14. Pasala S, Singer L, Arshad T, Roach K. Lactobacillus endocarditis in a healthy patient with probiotic use. IDCases. 2020;22:e00915. PubMed
  15. Agrawal S, Tuchman ES, Bruce MJ, Theodorou ME. Fatal Lactobacillus endocarditis in a patient with transcatheter aortic valve replacement. BMJ Case Rep. 2020;13(11):e236835.
  16. Antoun M, Hattab Y, Akhrass FA, Hamilton LD. Uncommon pathogen, Lactobacillus, causing infective endocarditis: Case report and review. Case Rep Infect Dis. 2020;2020:8833948. PubMed
  17. Rossi F, Amadoro C, Gasperi M, Colavita G. Lactobacilli infection case reports in the last three years and safety implications. Nutrients. 2022;14(6):1178. PubMed
  18. Franko B, Vaillant M, Recule C, Vautrin E, et al. Lactobacillus paracasei endocarditis in a consumer of probiotics. Med Mal Infect. 2013;43(4):171-3. PubMed
  19. Campbell RE, Miller A, Afroze A. Native valve endocarditis secondary to Lactobacillus paracasei bacteremia. Consultant. 2020;60(9):27-8. DOI
  20. Kato K, Funabashi N, Takaoka H, et al. Lactobacillus paracasei endocarditis in a consumer of probiotics with advanced and severe bicuspid aortic valve stenosis complicated with diffuse left ventricular mid-layer fibrosis. Int J Cardiol. 2016;224:157-161. PubMed

See these in context on the Bacillus Coagulans monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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