Interactions on record — worth a quick check against your medications. Based on 2 of 4 ingredients. Check your meds →
Dietary supplement

Source Of Life Yellow Lightning Ingredients & Drug Interactions

by Nature's Plus

Source Of Life Yellow Lightning label
See full label image
Powder Category: Other Combinations
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 30, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Source Of Life Yellow Lightning against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Source Of Life Yellow Lightning is a dietary supplement by Nature's Plus with 4 active ingredients. Its ingredients are commonly taken for eye health, age-related macular degeneration, cataract prevention.Based on those ingredients, 122 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Lycopene. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

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Check Your Meds Against Source Of Life Yellow Lightning by Nature's Plus

Ask about any prescription or over-the-counter medication and we check it for interactions with Source Of Life Yellow Lightning by Nature's Plus — and tell you which ingredient is responsible.

Pharmacist-reviewed data Checks every ingredient Answer in seconds
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Computed from our clinical databases

HelloPharmacist Scorecard of Source Of Life Yellow Lightning by Nature's Plus

Four independent checks of what is known — a summary of the available information, not a grade of the product itself.

Evidence for Intended Use
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not assessable

The stated purpose hasn't been mapped to our evidence data yet.

Why this rating?
  • We haven't mapped this product's purpose to our evidence data yet — it'll be graded on the next content refresh.
Ingredient Transparency
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 3 of its 3 active ingredients.
  • No proprietary blends here — you can verify the dose of every single component.
Known Interaction Concern
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 2 matched ingredients can interact with medications — Lycopene.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: anticoagulant / antiplatelet drugs.
  • For scale: 122 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.
Safety Information
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 2 of the 2 matched ingredients.
  • Pregnancy & breastfeeding safety ratings cover 2 of 2.
  • General safety write-ups exist for 2 of 2.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

HelloPharmacist summaryFully disclosed formula with no assessable stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.

Assessment coverage: 2 of 3 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Dec 21, 2012.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Source Of Life Yellow Lightning, straight from the product label.

Brand Nature's Plus
Barcode (UPC) 097467305755
Net contents 0.4 lb; 180 g
Market status Off market
Date entered into DSLD Dec 21, 2012
DSLD ID 15077
Product type Other Combinations
Supplement form Powder
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Vegetarian, Adult (18 - 50 Years), No Allergies, Dairy Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Source Of Life Yellow Lightning by Nature's Plus, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
6 Gram(s)
Maximum serving Sizes:
6 Gram(s)
Servings per container
30
UPC/BARCODE
097467305755
IngredientAmount% DV
Calories22 {Calories}--
Total Carbohydrates5 g2%
Sugar1 g--
Lutein3 mg--
Lycopene5 mg--
YELLOW LIGHTNING PROPRIETARY WHOLE FOOD BLEND6000 mg--

Other ingredients: Natural flavor, Guar Gum

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
General Statements

Nutritional Support for Free Radical Defense, Natural Energy Production and Overall Well-Being.*

Each power-packed Source of Life Yellow Lightning serving is enhanced with Activessence(R), a patented enzyme activation system that liberates energizing nutrition from foods. Source of Life Yellow Lightning captures lightning in a bottle, harnessing Nature’s awesome power to deliver pure, invigorating energy and unparalleled antioxidant activity!

100% NATURAL

ORAC VALUE 4000

POWER-PACKED ANTIOXIDANT WHOLE FOOD CONCENTRATE Supercharged with 25 Whole Foods

Naturally Refreshing Energy Drink Mix

Brand IP Statement(s)

Source of Life(R) Yellow Lightning(TM) delivers the amazing phytonutrient and powerful antioxidant benefits of Nature’s greatest yellow foods, a critical yet often overlooked pillar of healthy eating.

Guaranteed Burst of Energy(R)

(C)NATURAL ORGANICS(R)

Activessence(R) is a registered trademark of InterActive Enzymes, a division of Triarco Industries, Inc. U.S. Patent Nos. 6,099,844 and 6,132,727.

LYC-O-MATO(R) Tomato Lycopene Complex is a registered trademark of LycoRed Natural Products Industries Ltd., Beer Sheva, Israel.

FloraGLO LUTEIN(R) is a registered trademark of Kemin Industries, Inc.

Formula

With 25 whole food concentrates and extracts, including pineapple, golden kiwi, yellow squash, and pumpkin, Source of Life Yellow Lightning delivers a total ORAC value of 4000 per serving!

And, Source of Life Yellow Lightning includes powerful antioxidant carotenoids: 5 mg of lycopene and 3 mg of lutein.

• HYPO-ALLERGENIC

with Mango, Grapefruit, Pineapple & Melon

with Lutein & Lycopene

Formulation

VEGETARIAN

Free from artificial colors and preservatives. Free from the common allergens yeast, wheat, soy and milk.

Suggested/Recommended/Usage/Directions

DIRECTIONS: As a dietary supplement, add two rounded teaspoons of SOURCE OF LIFE YELLOW LIGHTNING to 8 oz. of water or juice and stir gently. SOURCE OF LIFE YELLOW LIGHTNING may also be sprinkled on food and added to shakes and smoothies.

FDA Disclaimer Statement

*This statement has not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

Storage

KEEP TIGHTLY CLOSED IN A COOL, DRY PLACE.

Precautions

KEEP OUT OF REACH OF CHILDREN.

General

PRODUCT NO. 30575 LBL. 1124410

FDA Statement of Identity

Dietary Supplement

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Source Of Life Yellow Lightning by Nature's Plus label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Source Of Life Yellow Lightning label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Source Of Life Yellow Lightning by Nature's Plus

These are the 4 active ingredients this product is made of. Select any to open its full monograph.

Serving size6 Gram(s) Dosage formPowder Servings per container30 Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

Sugar

1 g per serving

Lutein

No known
interactions
3 mg per serving Form: active Carotenoid

Lutein is a plant-based antioxidant pigment that concentrates in the eye, and the best evidence suggests it (often combined with zeaxanthin) may help...

Lutein monograph & interactions

Lycopene

Interacts with
122 drugs
5 mg per serving Form: active Carotenoid

Lycopene is a red plant pigment and antioxidant found mainly in tomatoes and other red fruits. Eating lycopene-rich foods is linked with possible hear...

Lycopene monograph & interactions

YELLOW LIGHTNING PROPRIETARY WHOLE FOOD BLEND

6000 mg per serving Form: Activessence, Apricot, Butternut Squash, Cantaloupe, Carrot, FOS, Golden Kiwi, Gooseberry, Grapefruit, Honeydew Melon, Lemon, Mango, Nectarine, Orange, Peach, Pear, Pineapple, Pumpkin, Rutabaga, Tangerine, Tomato, Yellow Apple, Yellow Beet, Yellow Fig, Yellow Pepper, Yellow Squash, Yellow Watermelon

Other (inactive) ingredients: Natural flavor, Guar Gum. These complete the product’s ingredient list but are not active constituents.

Interaction report

Source Of Life Yellow Lightning by Nature's Plus Drug Interactions

Source Of Life Yellow Lightning contains 4 ingredients, and 1 of them has known drug interactions. Altogether it interacts with 122 medications. Here’s the picture, then you can look up your own drug.

Want to check YOUR meds against Source Of Life Yellow Lightning?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
122Drugs
122 Moderate

Ingredients driving the most interactions

Lycopene 122

Individual Drug Interactions

The ingredients in Source Of Life Yellow Lightning interact with 122 drugs. Click any drug to see the details.

1 of the 4 ingredients in Source Of Life Yellow Lightning interact with drugs. Each result below shows which ingredient is responsible. Lycopene

Each ingredient & the kinds of drugs it affects

For each ingredient in Source Of Life Yellow Lightning with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Lycopene1 drug type · 122 drugs

Anticoagulant/Antiplatelet Drugs

Theoretically, taking lycopene with anticoagulant or antiplatelet drugs might increase the risk of bleeding.
In vitro research shows that lycopene has antiplatelet effects.

Likelihood Possible Evidence D
Lycopene full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Source Of Life Yellow Lightning, from the product label.

Nature's Plus

See all Nature's Plus products
Name
Nature's Plus
Street Address
548 Broadhollow Road
City
Melville
State
NY
ZipCode
11747
Web Address
www.naturesplus.com
Pharmacist Counseling Corner

Source Of Life Yellow Lightning by Nature's Plus: Common Questions

Does Source Of Life Yellow Lightning by Nature's Plus interact with any medications?
Yes. Based on its ingredients, Source Of Life Yellow Lightning has a known interaction with 122 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Source Of Life Yellow Lightning contains 4 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Source Of Life Yellow Lightning is safe with your meds?

Our pharmacists answer your medication & supplement questions — free.

Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Source Of Life Yellow Lightning label
Go deeper

The Full Monographs Behind Source Of Life Yellow Lightning’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Lutein

Lutein is a plant-based antioxidant pigment that concentrates in the eye, and the best evidence suggests it (often combined with zeaxanthin) may help slow progression of age-related macular...

Read the full Lutein monograph → Herb & supplement monograph

Lycopene

Interacts with 122 drugs

Lycopene is a red plant pigment and antioxidant found mainly in tomatoes and other red fruits. Eating lycopene-rich foods is linked with possible heart and prostate benefits, but evidence fr...

Read the full Lycopene monograph →
Sources

Sources & How We Checked

Source Of Life Yellow Lightning's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 12 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Lutein 2 references
  1. Brown L, Rimm EB, Seddon JM, et al. A prospective study of carotenoid intake and risk of cataract extraction in US men. Am J Clin Nutr 1999;70:517-24. PubMed
  2. Chasan-Taber L, Willett WC, Seddon JM, et al. A prospective study of carotenoid and vitamin A intakes and risk of cataract extraction in US women. Am J Clin Nutr 1999;70:509-16. PubMed

See these in context on the Lutein monograph →

Lycopene 10 references
  1. Sharma, J. B., Kumar, A., Kumar, A., Malhotra, M., Arora, R., Prasad, S., and Batra, S. Effect of lycopene on pre-eclampsia and intra-uterine growth retardation in primigravidas. Int J Gynaecol.Obstet. 2003;81(3):257-262. PubMed
  2. Hsiao, G., Wang, Y., Tzu, N. H., Fong, T. H., Shen, M. Y., Lin, K. H., Chou, D. S., and Sheu, J. R. Inhibitory effects of lycopene on in vitro platelet activation and in vivo prevention of thrombus formation. J Lab Clin Med 2005;146(4):216-226. PubMed
  3. Clark, P. E., Hall, M. C., Borden, L. S., Jr., Miller, A. A., Hu, J. J., Lee, W. R., Stindt, D., D'Agostino, R., Jr., Lovato, J., Harmon, M., and Torti, F. M. Phase I-II prospective dose-escalating trial of lycopene in patients with biochemical relapse o
  4. O'Kennedy, N., Crosbie, L., Whelan, S., Luther, V., Horgan, G., Broom, J. I., Webb, D. J., and Duttaroy, A. K. Effects of tomato extract on platelet function: a double-blinded crossover study in healthy humans. Am.J.Clin.Nutr. 2006;84(3):561-569. PubMed
  5. Jatoi, A., Burch, P., Hillman, D., Vanyo, J. M., Dakhil, S., Nikcevich, D., Rowland, K., Morton, R., Flynn, P. J., Young, C., and Tan, W. A tomato-based, lycopene-containing intervention for androgen-independent prostate cancer: results of a Phase II stu
  6. Schwenke, C., Ubrig, B., Thurmann, P., Eggersmann, C., and Roth, S. Lycopene for advanced hormone refractory prostate cancer: a prospective, open phase II pilot study. J.Urol. 2009;181(3):1098-1103. PubMed
  7. Banerjee, S., Jeyaseelan, S., and Guleria, R. Trial of lycopene to prevent pre-eclampsia in healthy primigravidas: results show some adverse effects. J.Obstet.Gynaecol.Res. 2009;35(3):477-482. PubMed
  8. Haseen, F., Cantwell, M. M., O'Sullivan, J. M., and Murray, L. J. Is there a benefit from lycopene supplementation in men with prostate cancer? A systematic review. Prostate Cancer Prostatic.Dis. 2009;12(4):325-332. PubMed
  9. Ilic, D., Forbes, K. M., and Hassed, C. Lycopene for the prevention of prostate cancer. Cochrane.Database.Syst.Rev. 2011;(11):CD008007. PubMed
  10. Sawardekar SB, Patel TC, Uchil D. Comparative evaluation of antiplatelet effect of lycopene with aspirin and the effect of their combination on platelet aggregation: an in vitro study. Indian J Pharmacol 2016;48:26-31. PubMed

See these in context on the Lycopene monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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