Major interaction on record — check this product against your medications before combining. Based on 3 of 4 ingredients. Check your meds →
Dietary supplement

Soy Lecithin Granules Ingredients & Drug Interactions

by GNC

Soy Lecithin Granules label
See full label image
Powder Category: Fat/fatty Acid
Most serious interaction: Major
Clinical methodology reviewed by · Updated Sep 9, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Soy Lecithin Granules against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Major

Soy Lecithin Granules is a dietary supplement by GNC with 4 active ingredients. Its ingredients are commonly taken for bone health and osteoporosis prevention, dietary calcium deficiency, heartburn relief (calcium carbonate antacids).Based on those ingredients, 184 medications have a known interaction with it, the most serious rated major. The ingredients most likely to interact are Calcium, Choline. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

Jump to a section

Check Your Meds Against Soy Lecithin Granules by GNC

Ask about any prescription or over-the-counter medication and we check it for interactions with Soy Lecithin Granules by GNC — and tell you which ingredient is responsible.

Pharmacist-reviewed data Checks every ingredient Answer in seconds
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HelloPharmacist Scorecard of Soy Lecithin Granules by GNC

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Jul 11, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 6 of its 6 active ingredients.
  • No proprietary blends here — you can verify the dose of every single component.

GNC Soy Lecithin Granules is a 6-ingredient powder. The active components are calcium, phosphorus, polyunsaturated and monounsaturated fats (from the soy lecithin itself), phosphatidyl choline, and choline.

Soy lecithin itself and tricalcium phosphate are listed as inactive ingredients — they're the carrier and structure of the product. Soy lecithin is a natural fat extracted from soybean oil and used in supplements and foods to help mix ingredients together and deliver nutrients.

The product concentrates on phosphatidyl choline and choline, which are fat-soluble compounds involved in cell membrane structure and brain signaling.

Does it work?

Leans against
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Leans against

The strongest graded evidence we hold for the stated purpose leans against a benefit.

Why this rating?
  • The label markets this product for: Brain, liver and cardiovascular health support.
  • We looked for evidence on: Age-related cognitive decline, Alzheimer disease, Cardiovascular disease (CVD), Cognitive function, Dementia, Dyslipidemia — and 4 related terms.
  • The closest evidence on file: Calcium is rated "Ineffective" for Cardiovascular disease (CVD) (Natural Medicines).
  • Also on file: Choline is rated "Insufficient Reliable Evidence To Rate" for Age-related cognitive decline, Alzheimer disease, Cardiovascular disease (CVD), Cognitive function, and more.

In our data, calcium in this product has established effectiveness for bone health — it's likely effective for osteoporosis — and it's effective for kidney failure, indigestion (dyspepsia), and high potassium (hyperkalemia). Phosphatidyl choline shows possibly effective evidence for ulcerative colitis, but the evidence for Alzheimer disease, nonalcoholic fatty liver disease, alcohol-related liver disease, and anxiety is insufficient.

Choline itself has insufficient evidence for athletic performance, bronchitis, age-related cognitive decline, and a few other uses we hold data on. The evidence for this product as a whole depends on what you're taking it for — check with us or your pharmacist about your specific goal.

The evidence, ingredient by ingredient Calcium Phosphatidylcholine Choline

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 3 of the 3 matched ingredients.
  • Pregnancy & breastfeeding safety ratings cover 3 of 3.
  • General safety write-ups exist for 3 of 3.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Calcium is generally well tolerated at recommended doses, though high amounts can cause problems. The most common side effects are belching, constipation, diarrhea, and stomach upset.

Rare serious concerns include kidney stones and calciphylaxis. High calcium intake (over 1500–2000 mg daily) has raised concerns in some research about prostate cancer risk and cardiovascular disease, though these findings remain debated.

Phosphatidyl choline is generally well tolerated but can cause bloating, diarrhea, altered taste, nausea, and vomiting — especially at high doses or with very large amounts (30 grams daily). Choline at high doses (9 grams or more daily) can cause a fishy body odor, diarrhea, nausea, and salivation.

Both are safe in food amounts; supplement doses should stay within recommended limits.

Side effects, ingredient by ingredient Calcium Phosphatidylcholine Choline

Meds to double-check

Major interaction found
Known Interaction Concern · database check
Major identified

At least one ingredient has a documented Major-severity interaction. Check your medications for a personalized result.

Why this rating?
  • 2 of the 3 matched ingredients can interact with medications — Choline, Calcium.
  • The most serious interaction on file is rated Major.
  • Some involve high-stakes drug classes: heart-rhythm medications; lithium.
  • For scale: 184 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before you take this product, double-check if you're on dolutegravir (Tivicay) or elvitegravir (Vitekta) — calcium significantly reduces their levels. If you receive intravenous ceftriaxone (Rocephin), avoid IV calcium entirely within 48 hours.

Also check whether you take levothyroxine (Synthroid), sotalol (Betapace), calcipotriene (Dovonex), or diltiazem (Cardizem) — you'll need to space doses from calcium. We could not check interactions for the phosphorus, polyunsaturated fat, or monounsaturated fat in this product.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with graded evidence leaning against its stated purpose. Major medication interactions have been identified, and safety information is well characterized.

This product is a source of calcium and choline, which support bone health and cellular function. It's worth considering if you're looking to boost calcium intake, but it's not right for you if you take integrase inhibitors, intravenous ceftriaxone, levothyroxine, or certain heart medications without spacing doses carefully.

Talk with your pharmacist before starting — especially if you take any prescription drugs — to make sure the timing works and no other interactions apply to you.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 3 of 6 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Dec 22, 2019.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Soy Lecithin Granules, straight from the product label.

Brand GNC
Barcode (UPC) 048107196868
Net contents 16.01 Ounce(s); 1 lb(s); 454 Gram(s)
Market status On market
Date entered into DSLD Dec 22, 2019
DSLD ID 210562
Product type Fat/fatty Acid
Supplement form Powder
Dietary claims / uses Nutrient, All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years), Dairy Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Soy Lecithin Granules by GNC, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
7.5 Gram(s)
Maximum serving Sizes:
7.5 Gram(s)
Servings per container
60
UPC/BARCODE
048107196868
IngredientAmount% DV
Calories40 Calorie(s)--
Total Carbohydrates1 Gram(s)1%
Phosphorus260 mg21%
Calcium60 mg5%
Total Fat4 Gram(s)5%
Polyunsaturated Fat2.5 Gram(s)--
Monounsaturated Fat0.5 Gram(s)--
Phosphatidyl Choline1.725 Gram(s)--
Saturated Fat1 Gram(s)5%
Choline230 mg42%

Other ingredients: Soy Lecithin, Tricalcium Phosphate

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Formula

Soy lecithin granules supply a naturally occurring combination of phosphatidyl choline (PC) and other phospholipids extracted from soybeans. Lecithin is a preferred source of choline and is used effectively by the body. Choline is essential for making acetylcholine, a messenger chemical that is important in sending messages from one nerve cell to another. Clinical studies have also shown that lecithin helps the body emulsify fat and provides dietary support for liver and cardiovascular health and nervous system function.

Formulation

Provides dietary support for brain, liver and cardiovascular health

No artificial colors, no artificial flavors, no preservatives, no wheat, no corn, no dairy.

FDA Statement of Identity

Dietary supplement

Suggested/Recommended/Usage/Directions

Directions: As a dietary supplement, take one tablespoon daily. For maximum benefits, take as directed every day.

Soy lecithin granules are convenient to use and can be sprinkled on food or mixed in juice or water.

Precautions

Contains: Soy.

Keep out of reach of children

General Statements

Notice: Significant product settling may occur.

Storage

Store in a cool, dry place.

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Soy Lecithin Granules by GNC label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Soy Lecithin Granules label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Soy Lecithin Granules by GNC

These are the 4 active ingredients this product is made of. Select any to open its full monograph.

Serving size7.5 Gram(s) Dosage formPowder Servings per container60 Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

Phosphorus

260 mg per serving

Calcium

Interacts with
168 drugs
60 mg per serving

Calcium is an essential mineral your body needs for strong bones, nerve signaling, and muscle function, and supplements can help fill gaps when diet f...

Calcium monograph & interactions

Phosphatidyl Choline

No known
interactions
1.725 Gram(s) per serving

Phosphatidylcholine is a phospholipid that is part of every cell membrane and a source of choline. People take it for liver, brain, and gut health, bu...

Phosphatidyl Choline monograph & interactions

Choline

Interacts with
16 drugs
230 mg per serving

Choline is an essential nutrient your body needs for liver function, brain health, and nerve signaling, and many people get enough from foods like egg...

Choline monograph & interactions

Other (inactive) ingredients: Soy Lecithin, Tricalcium Phosphate. These complete the product’s ingredient list but are not active constituents.

Interaction report

Soy Lecithin Granules by GNC Drug Interactions

Want to check YOUR meds against Soy Lecithin Granules?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
184Drugs
7 Major 143 Moderate 34 Minor

Ingredients driving the most interactions

Calcium 168
Choline 16

Individual Drug Interactions

The ingredients in Soy Lecithin Granules interact with 184 drugs. Click any drug to see the details.

2 of the 4 ingredients in Soy Lecithin Granules interact with drugs. Each result below shows which ingredient is responsible. Calcium Choline

Each ingredient & the kinds of drugs it affects

For each ingredient in Soy Lecithin Granules with known interactions, here are the types of medications they can affect. Open any type for the detail — or search your exact drug in the checker above.

Calcium18 drug types · 168 drugs

Ceftriaxone (Rocephin)

Co-administration of intravenous calcium and ceftriaxone can result in precipitation of a ceftriaxone-calcium salt in the lungs and kidneys.
Avoid administering intravenous calcium in any form, such as parenteral nutrition or Lactated Ringers, within 48 hours of intravenous ceftriaxone. Case reports in neonates show that administering intravenous ceftriaxone and calcium can result in precipitation of a ceftriaxone-calcium salt in the lungs and kidneys. In several cases, neonates have died as a result of this interaction. So far there are no reports in adults; however, there is still concern that this interaction might occur in adults.

Likelihood Probable Evidence D
Dolutegravir (Tivicay)

Calcium seems to reduce levels of dolutegravir.
Advise patients to take dolutegravir either 2 hours before or 6 hours after taking calcium supplements. Pharmacokinetic research suggests that taking calcium carbonate 1200 mg concomitantly with dolutegravir 50 mg reduces plasma levels of dolutegravir by almost 40%. Calcium appears to decrease levels of dolutegravir through chelation.

Likelihood Probable Evidence B
Elvitegravir (Vitekta)

Calcium seems to reduce levels of elvitegravir.
Advise patients to take elvitegravir either 2 hours before or 2 hours after taking calcium supplements. Pharmacokinetic research suggests that taking calcium along with elvitegravir can reduce blood levels of elvitegravir through chelation.

Likelihood Probable Evidence B
Aluminum

Calcium citrate might increase aluminum absorption and toxicity. Other types of calcium do not increase aluminum absorption.
Calcium citrate can increase the absorption of aluminum when taken with aluminum hydroxide. The increase in aluminum levels may become toxic, particularly in individuals with kidney disease. However, the effect of calcium citrate on aluminum absorption is due to the citrate anion rather than calcium cation. Calcium acetate does not appear to increase aluminum absorption.

Likelihood Possible Evidence B
Bictegravir/Emtricitabine/Tenofovir Alafenamide (Biktarvy)

Calcium might decrease levels of bictegravir/emtricitabine/tenofovir alafenamide by reducing its absorption when taken in a fasting state.
Advise patients that bictegravir/emtricitabine/tenofovir alafenamide and calcium can be taken together if taken with food. However, if taken on an empty stomach, bictegravir/emtricitabine/tenofovir alafenamide should not be taken with, or 2 hours after, calcium containing products.

Likelihood Probable Evidence D
Bisphosphonates

Calcium reduces the absorption of bisphosphonates.
Advise patients to take bisphosphonates at least 30 minutes before calcium, but preferably at a different time of day. Calcium supplements decrease absorption of bisphosphonates.

Likelihood Probable Evidence C
Calcipotriene (Dovonex)

Taking calcipotriene with calcium might increase the risk for hypercalcemia.
Calcipotriene is a vitamin D analog used topically for psoriasis. It can be absorbed in sufficient amounts to cause systemic effects, including hypercalcemia. Theoretically, combining calcipotriene with calcium supplements might increase the risk of hypercalcemia.

Likelihood Possible Evidence B
Digoxin (Lanoxin)

Using intravenous calcium with digoxin might increase the risk of fatal cardiac arrhythmias.
Hypercalcemia increases the risk of fatal cardiac arrhythmias with digoxin. However, one retrospective analysis of clinical data suggests that intravenous calcium does not increase the risk of dysrhythmias or mortality in patients receiving digoxin.

Likelihood Possible Evidence B
Diltiazem (Cardizem, Others)

Theoretically, calcium may reduce the therapeutic effects of diltiazem.
Hypercalcemia can reduce the effectiveness of verapamil in atrial fibrillation. Theoretically, calcium might increase this risk of hypercalcemia and reduce the effectiveness of diltiazem.

Likelihood Probable Evidence D
Levothyroxine (Synthroid, Others)

Calcium seems to reduce the absorption and effectiveness of levothyroxine.
Advise patients to take levothyroxine and calcium supplements at least 4 hours apart. Calcium reduces levothyroxine absorption, probably by forming insoluble complexes. Calcium carbonate supplements reduce effectiveness of levothyroxine in patients with hypothyroidism.

Likelihood Probable Evidence B
Lithium

Theoretically, concomitant use of calcium and lithium may increase this risk of hypercalcemia.
Clinical research suggests that long-term use of lithium may cause hypercalcemia in 10% to 60% of patients. Theoretically, concomitant use of lithium and calcium supplements may further increase this risk.

Likelihood Possible Evidence B
Quinolone Antibiotics

Calcium seems to reduce the absorption of quinolone antibiotics.
Advise patients to take oral quinolones at least 2 hours before or 4-6 hours after calcium supplements or calcium-fortified foods. Taking calcium at the same time as oral quinolones can reduce quinolone absorption. Calcium binds to quinolones in the gut.

Likelihood Probable Evidence B
Raltegravir (Isentress)

Calcium may reduce levels of raltegravir.
Pharmacokinetic research shows that taking a single dose of calcium carbonate 3000 mg along with raltegravir 400 mg twice daily modestly decreases the mean area under the curve of raltegravir, but the decrease does not necessitate a dose adjustment of raltegravir. However, a case of elevated HIV-1 RNA levels and documented resistance to raltegravir has been reported for a patient taking calcium carbonate 1 gram three times daily plus vitamin D3 (cholecalciferol) 400 IU three times daily in combination with raltegravir 400 mg twice daily for 11 months. It is thought that calcium reduced raltegravir levels by chelation, leading to treatment failure.

Likelihood Possible Evidence B
Sotalol (Betapace)

Calcium seems to reduce the absorption of sotalol.
Advise patients to separate doses by at least 2 hours before or 4-6 hours after calcium. Calcium appears to reduce the absorption of sotalol, probably by forming insoluble complexes.

Likelihood Possible Evidence B
Tetracycline Antibiotics

Calcium seems to reduce the absorption of tetracycline antibiotics.
Advise patients to take oral tetracyclines at least 2 hours before, or 4-6 hours after calcium supplements. Taking calcium at the same time as oral tetracyclines can reduce tetracycline absorption. Calcium binds to tetracyclines in the gut.

Likelihood Probable Evidence C
Thiazide Diuretics

Taking calcium along with thiazides might increase the risk of hypercalcemia and renal failure.
Thiazides reduce calcium excretion by the kidneys. Using thiazides along with moderately large amounts of calcium carbonate increases the risk of milk-alkali syndrome (hypercalcemia, metabolic alkalosis, renal failure). Patients may need to have their serum calcium levels and/or parathyroid function monitored regularly.

Likelihood Probable Evidence C
Verapamil (Calan, Others)

Theoretically, calcium may reduce the therapeutic effects of verapamil.
Hypercalcemia can reduce the effectiveness of verapamil in atrial fibrillation. Theoretically, use of calcium supplements may increase this risk of hypercalcemia and reduce the effectiveness of verapamil.

Likelihood Probable Evidence D
Calcium Channel Blockers

Intravenous calcium may decrease the effects of calcium channel blockers; oral calcium is unlikely to have this effect.
Intravenous calcium is used to decrease the effects of calcium channel blockers in the management of overdose. Intravenous calcium gluconate has been used before intravenous verapamil (Isoptin) to prevent or reduce the hypotensive effects without affecting the antiarrhythmic effects. But there is no evidence that dietary or supplemental calcium when taken orally interacts with calcium channel blockers.

Likelihood Unlikely Evidence D
Calcium full monograph & interactions

Choline1 drug type · 16 drugs

Atropine

Theoretically, choline might decrease the effects of atropine in the brain.
Animal research shows that administering choline one hour before administering atropine can attenuate atropine-induced decreases in brain levels of acetylcholine. Theoretically, concomitant use of choline and atropine may decrease the effects of atropine.

Likelihood Possible Evidence D
Choline full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Soy Lecithin Granules, from the product label.

GNC

See all GNC products
Name
General Nutrition Corporation
City
Pittsburgh
State
PA
ZipCode
15222
Phone Number
1-888-462-2548
Web Address
gnc.com
Pharmacist Counseling Corner

Soy Lecithin Granules by GNC: Common Questions

Does Soy Lecithin Granules by GNC interact with any medications?
Yes. Based on its ingredients, Soy Lecithin Granules has a known interaction with 184 medications, including 7 rated major. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Soy Lecithin Granules contains 4 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Is this safe to take during pregnancy or while breastfeeding?
Calcium is likely safe in pregnancy at recommended amounts — adequate calcium is important for you and your baby. For choline, the data says it's likely safe during pregnancy and breastfeeding. However, stick to recommended doses and check with your doctor or midwife, especially if you're considering higher amounts than a prenatal vitamin provides. Phosphatidyl choline doesn't have enough data on supplement safety beyond food sources in pregnancy and breastfeeding, so ask your provider about that ingredient specifically.
What are the most common side effects?
From calcium, you might notice belching, constipation, diarrhea, or stomach upset. Phosphatidyl choline can cause bloating, diarrhea, altered taste, nausea, or vomiting, especially at high doses. Choline at very high doses can cause a fishy body odor and GI upset. Starting with a lower dose and taking it with food may help reduce these effects.
Can this help with bone health?
Yes — calcium in this product is likely effective for osteoporosis and supports bone health. Calcium is also effective for kidney failure, indigestion, and high potassium levels. Whether this product meets your specific calcium needs depends on the amount per serving and your total daily intake — ask your pharmacist to help you figure that out.
Does it work for memory or brain health?
Choline and phosphatidyl choline are involved in brain function, but the evidence we hold for these ingredients on Alzheimer disease, age-related cognitive decline, and related uses is insufficient — meaning we don't have enough reliable data to say whether they work for those purposes. Phosphatidyl choline does show possibly effective evidence for ulcerative colitis.
What's the difference between the active ingredients — calcium, choline, and phosphatidyl choline?
Calcium is a mineral that builds and maintains bones and is involved in muscle and nerve function. Choline is a nutrient that helps make cell membranes and a brain chemical called acetylcholine. Phosphatidyl choline is a fat-based form of choline that's better absorbed and is found naturally in soy lecithin. This product gives you all three together.
Is there a risk with very high doses?
Yes. Very high calcium intake (over 1500–2000 mg daily) has raised concerns in some studies about prostate cancer and heart disease, though research is still mixed. Choline has a daily upper limit of 3.5 grams — doses above that can cause nausea, vomiting, diarrhea, and a fishy body odor. Stick to recommended amounts unless your doctor advises otherwise.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Soy Lecithin Granules label
Go deeper

The Full Monographs Behind Soy Lecithin Granules’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Calcium

Interacts with 168 drugs

Calcium is an essential mineral your body needs for strong bones, nerve signaling, and muscle function, and supplements can help fill gaps when diet falls short. Most people do best getting...

Read the full Calcium monograph → Herb & supplement monograph

Phosphatidylcholine

Phosphatidylcholine is a phospholipid that is part of every cell membrane and a source of choline. People take it for liver, brain, and gut health, but solid human evidence is limited for mo...

Read the full Phosphatidylcholine monograph → Herb & supplement monograph

Choline

Interacts with 16 drugs

Choline is an essential nutrient your body needs for liver function, brain health, and nerve signaling, and many people get enough from foods like eggs, meat, and fish. Supplements may help...

Read the full Choline monograph →
Sources

Sources & How We Checked

Soy Lecithin Granules's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 91 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Calcium 62 references
  1. Shils M, Olson A, Shike M. Modern Nutrition in Health and Disease. 8th ed. Philadelphia, PA: Lea and Febiger, 1994.
  2. Hernandez-Avila M, Gonzalez-Cossio T, Hernandez-Avila JE, et al. Dietary calcium supplements to lower blood lead levels in lactating women: a randomized placebo-controlled trial. Epidemiology 2003;14:206-12.. PubMed
  3. Thys-Jacobs S, Ceccarelli S, Bierman A, et al. Calcium supplementation in premenstrual syndrome: a randomized crossover trial. J Gen Intern Med 1989;4:183-9. PubMed
  4. Maton PN, Burton ME. Antacids revisited: a review of their clinical pharmacology and recommended therapeutic use. Drugs 1999;57:855-70.
  5. Clemens JD, Feinstein AR. Calcium carbonate and constipation: a historical review of medical mythopoeia. Gastroenterology 1977;72:957-61. DOI
  6. Saunders D, Sillery J, Chapman R. Effect of calcium carbonate and aluminum hydroxide on human intestinal function. Dig Dis Sci 1988;33:409-13. PubMed
  7. Friedman PA, Bushinsky DA. Diuretic effects on calcium metabolism. Semin Nephrol 1999;19:551-6.
  8. Koo WK, Walters JC, Esterlitz J, et al. Maternal calcium supplementation and fetal bone mineralization. Obstet Gynecol 1999;94:577-82. DOI
  9. Raman L, Rajalakshmi K, Krishnamachari KAVR, et al. Effect of calcium supplementation to undernourished mothers during pregnancy on the bone density of the neonates. Am J Clin Nutr 1978; 31:466-9. DOI
  10. Murry JJ, Healy MD. Drug-mineral interactions: a new responsibility for the hospital dietician. J Am Diet Assoc 1991;91:66-73.
  11. Chan JM, Giovannucci E, Andersson SO, et al. Dairy products, calcium, phosphorous, vitamin D, and risk of prostate cancer. Cancer Causes Control 1998;9:559-66.
  12. Butner LE, Fulco PP, Feldman G, et al. Calcium carbonate-induced hypothyroidism. Ann Intern Med 2000:132:595. PubMed
  13. Schneyer CR. Calcium carbonate and reduction of levothyroxine efficacy. JAMA 1998;279:750. PubMed
  14. Moser LR, Smythe MA, Tisdale JE. The use of calcium salts in the prevention and management of verapamil-induced hypotension. Ann Pharmacother 2000;34:622-9. PubMed
  15. Singh N, Singh PN, Hershman JM. Effect of calcium carbonate on the absorption of levothyroxine. JAMA 2000;283:2822-5. PubMed
  16. Kahela P, Anttila M, Tikkanen R, Sundquist H. Effect of food, food constituents and fluid volume on the bioavailability of sotalol. Acta Pharmacol Toxicol (Copenh) 1979;44:7-12.. PubMed
  17. Pletz MW, Petzold P, Allen A, et al. Effect of calcium carbonate on bioavailability of orally administered gemifloxacin. Antimicrob Agents Chemother 2003;47:2158-60.. PubMed
  18. Bar-Or D, Yoel G. Calcium and calciferol antagonize effect of verapamil in atrial fibrillation. Br Med J 1981;282:1585-6.
  19. Decktor DL, Robinson M, Maton PN, et al. Effects of aluminum/magnesium hydroxide and calcium carbonate on esophageal and gastric pH in subjects with heartburn. Am J Ther 1995;2:546-52. PubMed
  20. Simoneau G. Absence of rebound effect with calcium carbonate. Eur J Drug Metab Pharmacokinet 1996;21:351-7. PubMed
  21. Peters ML, Leonard M, Licata AA. Role of alendronate and risedronate in preventing and treating osteoporosis. Cleve Clin J Med 2001;68:945-51. PubMed
  22. Bourke JF, Mumford R, Whittaker P, et al. The effects of topical calcipotriol on systemic calcium homeostasis in patients with chronic plaque psoriasis. J Am Acad Dermatol 1997;37:929-34.
  23. Gueguen L, Pointillart A. The bioavailability of dietary calcium. J Am Coll Nutr 2000;19:119s-136s. PubMed
  24. Vella A, Gerber TC, Hayes DL, Reeder GS. Digoxin, hypercalcaemia, and cardiac conduction. Postgrad Med J 1999;75:554-6. PubMed
  25. Bania TC, Blaufeux B, Hughes S, et al. Calcium and digoxin vs. calcium alone for severe verapamil toxicity. Acad Emerg Med 2000;7:1089-96. PubMed
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See these in context on the Calcium monograph →

Phosphatidylcholine 15 references
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See these in context on the Phosphatidylcholine monograph →

Choline 14 references
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See these in context on the Choline monograph →

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DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

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