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Dietary supplement

Sparga Ingredients & Drug Interactions

by NutraMedix

Sparga label
See full label image
Liquid Category: Botanical
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 23, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Sparga against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Sparga is a dietary supplement by NutraMedix with 1 active ingredient. Its ingredients are commonly taken for mild fluid retention (diuretic), urinary tract support, digestive health and fiber.Based on those ingredients, 76 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Asparagus Leaf, Stem Extract. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

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Check Your Meds Against Sparga by NutraMedix

Ask about any prescription or over-the-counter medication and we check it for interactions with Sparga by NutraMedix — and tell you which ingredient is responsible.

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HelloPharmacist Scorecard of Sparga by NutraMedix

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Jul 11, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

Sparga is a single-ingredient liquid supplement containing asparagus leaf and stem extract. The liquid form also includes mineral water and ethanol as inactive ingredients.

Does it work?

No specific claim
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
General wellness

This Asparagus product is marketed for general wellness, not a specific health condition, so there's no single claim to grade — see Asparagus's own graded uses on its monograph.

Why this rating?
  • The label markets general wellness (“detox support”), not a specific health condition, so there is no single claim to grade against clinical-evidence data.

The evidence for asparagus extract isn't established for any of the conditions we have data on — acne, cancer, constipation, high blood pressure, intestinal parasites, and kidney stones all carry a rating of insufficient reliable evidence. That means the research hasn't been done or isn't strong enough yet to say whether it works for these uses.

The evidence, ingredient by ingredient Asparagus

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Asparagus as a food is generally well tolerated, but concentrated extracts like this one are less well studied. The safety data advises caution with medicinal doses because we don't have enough information on how safe they are at supplement levels.

Some people can have allergic reactions to asparagus, especially those sensitive to onions, garlic, leeks, or chives — reactions can range from itchy eyes and runny nose to rash, throat tightness, breathing trouble, and rarely anaphylaxis. One clinical trial of a combination product containing asparagus root reported constipation, bloating, stomach pain, nausea, dry mouth, and gallbladder complaints in up to half the participants, though it's unclear whether asparagus alone caused these.

That same trial reported gout in about 2% of people, again with unclear attribution.

Side effects, ingredient by ingredient Asparagus

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Asparagus.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: lithium.
  • For scale: 76 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Check with your pharmacist before using Sparga if you take diuretic drugs (water pills) or lithium. Both carry Moderate severity interactions with asparagus extract based on animal and theoretical evidence.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula marketed for general wellness rather than one specific gradeable purpose. Moderate medication interactions have been identified, and safety information is well characterized.

Sparga may be considered by someone looking to try asparagus extract, but the evidence for its effectiveness isn't established yet. If you take diuretics or lithium, definitely talk with your pharmacist or doctor before starting — the theoretical interaction could matter for your care.

If you have a history of asparagus allergy or sensitivity to garlic and onion family plants, steer clear.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Jul 24, 2025.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Sparga, straight from the product label.

Brand NutraMedix
Barcode (UPC) 728650081155
Net contents 1 Fluid Ounce(s); 30 mL
Market status On market
Date entered into DSLD Jul 24, 2025
DSLD ID 334056
Product type Botanical
Supplement form Liquid
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years), Women (not pregnant or lactating)
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Sparga by NutraMedix, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
10 Drop(s)
Maximum serving Sizes:
10 Drop(s)
Servings per container
60
UPC/BARCODE
728650081155
IngredientAmount% DV
Asparagus Leaf, Stem Extract0.5 mL--

Other ingredients: Mineral Water, Ethanol

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Suggested/Recommended/Usage/Directions

Shake well before each use: Put 10 drops in 4 oz (120 mL) of water and wait one minute before drinking. May be taken several times per day as needed or as directed by your physician.

Precautions

Do not use if pregnant or nursing.

Stop use if adverse reactions develop.

FDA Disclaimer Statement

This statement has not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

Formulation

Detox support

FDA Statement of Identity

Dietary Supplement

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Sparga by NutraMedix label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Sparga label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Sparga by NutraMedix

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size10 Drop(s) Dosage formLiquid Servings per container60 Amounts shown are per serving.

Asparagus Leaf, Stem Extract

Interacts with
76 drugs
0.5 mL per serving Form: Asparagus Leaf Extract, Asparagus Stem Extract

Asparagus is a nutritious vegetable that is safe and healthy to eat as part of a normal diet. Most of its claimed medicinal benefits, such as use as a...

Asparagus Leaf, Stem Extract monograph & interactions

Other (inactive) ingredients: Mineral Water, Ethanol. These complete the product’s ingredient list but are not active constituents.

Interaction report

Sparga by NutraMedix Drug Interactions

Want to check YOUR meds against Sparga?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
76Drugs
76 Moderate

Ingredients driving the most interactions

Asparagus Leaf, Stem Extract 76

Individual Drug Interactions

The ingredients in Sparga interact with 76 drugs. Click any drug to see the details.

1 of the 1 ingredient in Sparga interact with drugs. Each result below shows which ingredient is responsible. Asparagus Leaf, Stem Extract

Each ingredient & the kinds of drugs it affects

For each ingredient in Sparga with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Asparagus Leaf, Stem Extract2 drug types · 76 drugs

Diuretic Drugs

Theoretically, asparagus root might increase diuresis and electrolyte loss when used with diuretic drugs.
Animal studies show that asparagus root extracts have diuretic effects. This effect has not been reported in humans.

Likelihood Possible Evidence D
Lithium

Theoretically, asparagus root might cause diuresis, reducing lithium clearance.
Animal studies show that asparagus root extracts have diuretic effects. Theoretically, this might reduce excretion and increase levels of lithium. The dose of lithium might need to be decreased.

Likelihood Probable Evidence D
Asparagus Leaf, Stem Extract full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Sparga, from the product label.

NutraMedix

See all NutraMedix products
Name
NutraMedix
City
Jupiter
State
Florida
ZipCode
33458
Phone Number
561-745-2917
Web Address
www.nutramedix.com
Pharmacist Counseling Corner

Sparga by NutraMedix: Common Questions

Does Sparga by NutraMedix interact with any medications?
Yes. Based on its ingredients, Sparga has a known interaction with 76 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Sparga contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Can I take Sparga if I'm on a water pill?
Not without checking first. Asparagus extract may theoretically increase water and electrolyte loss when combined with diuretics. Your dose might need adjusting, so talk to your pharmacist or doctor before starting.
Can I take Sparga if I'm on lithium?
Not without checking first. Asparagus extract might reduce how your body clears lithium, which could raise its level. Your lithium dose might need to be lowered, so definitely run this by your pharmacist or doctor before starting.
What's the difference between eating asparagus and taking this supplement?
Eating asparagus as food is safe for most people. This is a concentrated extract at medicinal doses, which haven't been proven safe, so caution is advised — that's why we don't have enough data on how safe it is at supplement levels.
Can I take Sparga if I have a garlic or onion allergy?
Be careful. People sensitive to garlic, onions, leeks, and chives are at higher risk of allergic reactions to asparagus. Reactions can range from itching and sneezing to rash, throat tightness, and difficulty breathing. If you have that sensitivity, talk to your pharmacist first.
Does Sparga actually work for the things it's marketed for?
The evidence isn't there yet. We don't have reliable studies showing it works for acne, cancer, constipation, high blood pressure, parasites, or kidney stones.
What side effects should I watch for?
Allergic reactions are possible — itchy eyes, runny nose, rash, or difficulty breathing. One study of an asparagus-containing product reported constipation, bloating, stomach pain, nausea, and dry mouth in up to half the people, though it's not certain asparagus alone caused those. Gout was reported in about 2% in that same study.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Sparga label
Go deeper

The Full Monographs Behind Sparga’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Asparagus

Interacts with 76 drugs

Asparagus is a nutritious vegetable that is safe and healthy to eat as part of a normal diet. Most of its claimed medicinal benefits, such as use as a diuretic or for urinary health, come fr...

Read the full Asparagus monograph →
Sources

Sources & How We Checked

Sparga's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 14 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Asparagus 14 references
  1. The Review of Natural Products by Facts and Comparisons. St. Louis, MO: Wolters Kluwer Co., 1999.
  2. Electronic Code of Federal Regulations. Title 21. Part 182 -- Substances Generally Recognized As Safe. Available at: https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfcfr/CFRSearch.cfm?CFRPart=182
  3. Volz T, Berner D, Weigert C, et al. Fixed food eruption caused by asparagus. J Allergy Clin Immunol 2005;116:1390-2. PubMed
  4. Huang X, Kong L. Steroidal saponins from roots of Asparagus officinalis. Steroids 2006;71:171-6. PubMed
  5. Rodriguez R, Jaramillo S, Rodriguez G, et al. Antioxidant activity of ethanolic extracts from several asparagus cultivars. J Agric Food Chem 2005;53:5212-7. PubMed
  6. Rieker J, Ruzicka T, Neumann NJ, Homey B. Protein contact dermatitis to asparagus. J Allergy Clin Immunol 2004;113:354-5. PubMed
  7. Tabar AI, Alvarez-Puebla MJ, Gomez B, et al. Diversity of asparagus allergy: clinical and immunological features. Clin Exp Allergy 2004;34:131-6. PubMed
  8. Rademaker M, Yung A. Contact dermatitis to Asparagus officinalis. Australas J Dermatol 2000;41:262-3.
  9. Misico, R. I., Nicotra, V. E., Oberti, J. C., Barboza, G., Gil, R. R., and Burton, G. Withanolides and related steroids. Prog.Chem.Org.Nat.Prod. 2011;94:127-229.
  10. Hausen BM, Wolf C. 1,2,3-Trithiane-5-carboxylic acid, a first contact allergen from Asparagus officinalis (Liliaceae). Am J Contact Dermat 1996;7(1):41-46. PubMed
  11. Escribano MM, Munoz-Bellido FJ, Serrano P, et al. Acute urticaria after ingestion of asparagus. Allergy 1998;53(6):622-623. PubMed
  12. Chrubasik S, Droste C, Black A. Asparagus P(R) cannot compete with first-line diuretics in lowering the blood pressure in treatment-requiring antihypertensives. Phytother Res 2009;23:1345-6.
  13. Gaus BM, Scheiba N, Schäkel K. Asparagus-induced fixed food eruptions mimicking cutaneous lupus. Acta Derm Venereol 2014;94:731-2. PubMed
  14. Yanagi T, Shimizu H, Shimizu T. Occupational contact dermatitis caused by asparagus. Contact Dermatitis 2010;63:54. PubMed

See these in context on the Asparagus monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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