Spinach Extract Ingredients & Drug Interactions
What is this page for?
First and foremost: checking Spinach Extract against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.
Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy
Spinach Extract is a dietary supplement by BulkSupplements.com with 1 active ingredient. Its ingredients are commonly taken for general nutrition and antioxidant support, eye health, heart health and blood pressure.Based on those ingredients, 88 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Spinach extract. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.
Check Your Meds Against Spinach Extract by BulkSupplements.com
Ask about any prescription or over-the-counter medication and we check it for interactions with Spinach Extract by BulkSupplements.com — and tell you which ingredient is responsible.
AI summaries are generated from our interaction database for education only — always confirm with your pharmacist. How we use AI
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HelloPharmacist Scorecard of Spinach Extract by BulkSupplements.com
Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.
What’s inside
Full disclosure
This product is pure spinach extract powder — a single active ingredient in a concentrated form. There are no other active ingredients or fillers listed.
Does it work?
Couldn't assess
The evidence for spinach extract isn't established in the data we hold. We have insufficient reliable evidence to rate its use for nonalcoholic fatty liver disease, cognitive function, muscle strength, obesity, or polycystic ovary syndrome.
If you're considering it for a specific health goal, talk with your doctor or pharmacist about whether the evidence supports it for your situation.
How safe is it?
Well-documented data
Spinach as a food is well tolerated and considered safe for most people, including during pregnancy and breastfeeding. As a supplement powder, it's generally well tolerated when taken orally.
Allergies are possible in sensitive individuals. Rare serious effects include methemoglobinemia in infants under 4 months old, and inhalation of spinach powder has been linked to lung inflammation and occupational asthma in occupational settings.
Contact dermatitis from spinach on skin has also been reported, though rarely.
Meds to double-check
Moderate interaction found
Before you start, check with your doctor or pharmacist if you take antidiabetes drugs — spinach may lower blood glucose and could raise your risk of low blood sugar. Also check if you take warfarin (a blood thinner) — spinach's vitamin K content can interfere with how it works and may require a dose adjustment.
These are the medication types we have data for with this product.
The bottom line
Scorecard at a glanceFully disclosed formula with no assessable stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.
Spinach extract is a straightforward single-ingredient product that's nutritious and well tolerated as a food. If you take diabetes medications or warfarin, you'll need to check with your doctor or pharmacist before adding it — the interactions are real and may require dose changes.
For most other people with no blood sugar or blood clotting medications, it's generally low-risk, though we don't have solid evidence it works for most of the conditions it's marketed for.
Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI
Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Apr 23, 2024.
This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed
General information
Key facts about Spinach Extract, straight from the product label.
| Brand | BulkSupplements.com |
|---|---|
| Barcode (UPC) | X0018BLLIB |
| Net contents | 1 Kilogram(s); 35.3 Ounce(s) |
| Market status | On market |
| Date entered into DSLD | Apr 23, 2024 |
| DSLD ID | 311637 |
| Product type | Botanical |
| Supplement form | Powder |
| Dietary claims / uses | All Other, Structure/Function |
| Intended target group(s) | Adult (18 - 50 Years), Gluten Free, Dairy Free |
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.
Supplement Facts
The label details for Spinach Extract by BulkSupplements.com, sourced from the NIH Dietary Supplement Label Database.
Supplement Facts
| Ingredient | Amount | % DV |
|---|---|---|
| Spinach extract | 1000 mg | -- |
Tap any ingredient to jump to its full detail below.
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Brand IP Statement(s)
BulkSupplements.com Clean & pure bulk supplements
Formulation
Color may vary
Free of: Added sugar, soy, dairy, yeast, gluten, additives
FDA Disclaimer Statement
Warning: This product is not intended to diagnose, treat, cure, or prevent any disease.
Precautions
Always consult a physician before taking any dietary supplement.
Keep out of reach of children.
Suggested/Recommended/Usage/Directions
Suggested use: As a dietary supplement, take 1000 mg (about 1/3 tsp) once or twice daily, or as directed by a physician.
Storage
Store in a dry, cool place Contents are sold by weight, not volume. Settling may occur.
General Statements
New Use an accurate milligram scale.
Is this label outdated? Report a formula or label change and our pharmacy team will review it.
Spinach Extract by BulkSupplements.com label
The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.
Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.
View the full label (PDF)The Ingredients in Spinach Extract by BulkSupplements.com
This is the 1 active ingredient this product is made of. Select it to open its full monograph.
Serving size1000 mg Dosage formPowder Servings per container1000 Amounts shown are per serving.
Spinach extract
Interacts with88 drugs
Spinach is a nutrient-dense leafy green that is a healthy part of a balanced diet, providing vitamins, minerals, fiber, and antioxidants. While it is...
Spinach extract monograph & interactionsSpinach Extract by BulkSupplements.com Drug Interactions
HelloPharmacist Interaction Report
Spinach Extract by BulkSupplements.com contains one active ingredient — spinach extract — which interacts with blood sugar medications and warfarin (a blood thinner).
The most serious concern is with antidiabetes drugs: spinach may lower blood glucose on its own, and taking it alongside diabetes medication could push your blood sugar too low (hypoglycemia). If you take diabetes drugs, you'll need to monitor your blood glucose closely and may need a dose adjustment.
Read the full breakdown — every affected drug type, severity by severity
Spinach is also high in vitamin K, which works against warfarin by interfering with how the drug thins your blood. Research shows that eating spinach with a single meal won't throw off your warfarin dose, but taking it daily for a week or longer will require your warfarin dose to be adjusted.
If you're on warfarin, keep your spinach intake consistent day to day — don't suddenly increase or decrease it.
Although these two drug types are the ones we have data for, we hold documented interactions spanning 88 individual medications total across the affected categories. Use the interaction checker on this page to search your exact drugs before you start.
Check your own medications below · Editorial policy · How we use AI
Want to check YOUR meds against Spinach Extract?
Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.
Go to the checkerIngredients driving the most interactions
Individual Drug Interactions
The ingredients in Spinach Extract interact with 88 drugs. Click any drug to see the details.
1 of the 1 ingredient in Spinach Extract interact with drugs. Each result below shows which ingredient is responsible. Spinach extract
AcarboseGlucobay, Prandase, Precose
How Acarbose interacts with Spinach Extract — through 1 ingredient. Tap an ingredient for the detail:
Spinach ExtractAntidiabetes Drugs Moderate
Interaction Summary
There are claims that spinach leaves have hypoglycemic effects.
Read the full Spinach Extract + Acarbose interactionAcetohexamideDymelor
How Acetohexamide interacts with Spinach Extract — through 1 ingredient. Tap an ingredient for the detail:
Spinach ExtractAntidiabetes Drugs Moderate
Interaction Summary
There are claims that spinach leaves have hypoglycemic effects.
Read the full Spinach Extract + Acetohexamide interactionAlbiglutideTanzeum
How Albiglutide interacts with Spinach Extract — through 1 ingredient. Tap an ingredient for the detail:
Spinach ExtractAntidiabetes Drugs Moderate
Interaction Summary
There are claims that spinach leaves have hypoglycemic effects.
Read the full Spinach Extract + Albiglutide interactionAlogliptinNesina
How Alogliptin interacts with Spinach Extract — through 1 ingredient. Tap an ingredient for the detail:
Spinach ExtractAntidiabetes Drugs Moderate
Interaction Summary
There are claims that spinach leaves have hypoglycemic effects.
Read the full Spinach Extract + Alogliptin interactionAlogliptin, MetforminKazano
How Alogliptin, Metformin interacts with Spinach Extract — through 1 ingredient. Tap an ingredient for the detail:
Spinach ExtractAntidiabetes Drugs Moderate
Interaction Summary
There are claims that spinach leaves have hypoglycemic effects.
Read the full Spinach Extract + Alogliptin, Metformin interactionAlogliptin, PioglitazoneOseni
How Alogliptin, Pioglitazone interacts with Spinach Extract — through 1 ingredient. Tap an ingredient for the detail:
Spinach ExtractAntidiabetes Drugs Moderate
Interaction Summary
There are claims that spinach leaves have hypoglycemic effects.
Read the full Spinach Extract + Alogliptin, Pioglitazone interactionAntidiabetes, Dipeptidyl Peptidase-4 (dpp-iv) InhibitorGlyxambi
How Antidiabetes, Dipeptidyl Peptidase-4 (dpp-iv) Inhibitor interacts with Spinach Extract — through 1 ingredient. Tap an ingredient for the detail:
Spinach ExtractAntidiabetes Drugs Moderate
Interaction Summary
There are claims that spinach leaves have hypoglycemic effects.
Read the full Spinach Extract + Antidiabetes, Dipeptidyl Peptidase-4 (dpp-iv) Inhibitor interactionCanagliflozinInvokana
How Canagliflozin interacts with Spinach Extract — through 1 ingredient. Tap an ingredient for the detail:
Spinach ExtractAntidiabetes Drugs Moderate
Interaction Summary
There are claims that spinach leaves have hypoglycemic effects.
Read the full Spinach Extract + Canagliflozin interactionCanagliflozin, MetforminInvokamet
How Canagliflozin, Metformin interacts with Spinach Extract — through 1 ingredient. Tap an ingredient for the detail:
Spinach ExtractAntidiabetes Drugs Moderate
Interaction Summary
There are claims that spinach leaves have hypoglycemic effects.
Read the full Spinach Extract + Canagliflozin, Metformin interactionCanagliflozin, Metformin HydrochlorideInvokamet XR
How Canagliflozin, Metformin Hydrochloride interacts with Spinach Extract — through 1 ingredient. Tap an ingredient for the detail:
Spinach ExtractAntidiabetes Drugs Moderate
Interaction Summary
There are claims that spinach leaves have hypoglycemic effects.
Read the full Spinach Extract + Canagliflozin, Metformin Hydrochloride interactionChlorpropamideChlorpropam, Diabinese
How Chlorpropamide interacts with Spinach Extract — through 1 ingredient. Tap an ingredient for the detail:
Spinach ExtractAntidiabetes Drugs Moderate
Interaction Summary
There are claims that spinach leaves have hypoglycemic effects.
Read the full Spinach Extract + Chlorpropamide interactionDapagliflozinFarxiga
How Dapagliflozin interacts with Spinach Extract — through 1 ingredient. Tap an ingredient for the detail:
Spinach ExtractAntidiabetes Drugs Moderate
Interaction Summary
There are claims that spinach leaves have hypoglycemic effects.
Read the full Spinach Extract + Dapagliflozin interactionDapagliflozin Propanediol, MetforminXigduo XR
How Dapagliflozin Propanediol, Metformin interacts with Spinach Extract — through 1 ingredient. Tap an ingredient for the detail:
Spinach ExtractAntidiabetes Drugs Moderate
Interaction Summary
There are claims that spinach leaves have hypoglycemic effects.
Read the full Spinach Extract + Dapagliflozin Propanediol, Metformin interactionDapagliflozin Propanediol, Saxagliptin HydrochlorideQtern
How Dapagliflozin Propanediol, Saxagliptin Hydrochloride interacts with Spinach Extract — through 1 ingredient. Tap an ingredient for the detail:
Spinach ExtractAntidiabetes Drugs Moderate
Interaction Summary
There are claims that spinach leaves have hypoglycemic effects.
Read the full Spinach Extract + Dapagliflozin Propanediol, Saxagliptin Hydrochloride interactionDapagliflozin, Metformin Hydrochloride, Saxagliptin HydrochlorideQternmet XR
How Dapagliflozin, Metformin Hydrochloride, Saxagliptin Hydrochloride interacts with Spinach Extract — through 1 ingredient. Tap an ingredient for the detail:
Spinach ExtractAntidiabetes Drugs Moderate
Interaction Summary
There are claims that spinach leaves have hypoglycemic effects.
Read the full Spinach Extract + Dapagliflozin, Metformin Hydrochloride, Saxagliptin Hydrochloride interactionDasiglucagon HydrochlorideZegalogue
How Dasiglucagon Hydrochloride interacts with Spinach Extract — through 1 ingredient. Tap an ingredient for the detail:
Spinach ExtractAntidiabetes Drugs Moderate
Interaction Summary
There are claims that spinach leaves have hypoglycemic effects.
Read the full Spinach Extract + Dasiglucagon Hydrochloride interactionDulaglutideTrulicity
How Dulaglutide interacts with Spinach Extract — through 1 ingredient. Tap an ingredient for the detail:
Spinach ExtractAntidiabetes Drugs Moderate
Interaction Summary
There are claims that spinach leaves have hypoglycemic effects.
Read the full Spinach Extract + Dulaglutide interactionEmpagliflozinJardiance
How Empagliflozin interacts with Spinach Extract — through 1 ingredient. Tap an ingredient for the detail:
Spinach ExtractAntidiabetes Drugs Moderate
Interaction Summary
There are claims that spinach leaves have hypoglycemic effects.
Read the full Spinach Extract + Empagliflozin interactionEmpagliflozin, Linagliptin, Metformin HydrochlorideTrijardy XR
How Empagliflozin, Linagliptin, Metformin Hydrochloride interacts with Spinach Extract — through 1 ingredient. Tap an ingredient for the detail:
Spinach ExtractAntidiabetes Drugs Moderate
Interaction Summary
There are claims that spinach leaves have hypoglycemic effects.
Read the full Spinach Extract + Empagliflozin, Linagliptin, Metformin Hydrochloride interactionEmpagliflozin, MetforminSynjardy
How Empagliflozin, Metformin interacts with Spinach Extract — through 1 ingredient. Tap an ingredient for the detail:
Spinach ExtractAntidiabetes Drugs Moderate
Interaction Summary
There are claims that spinach leaves have hypoglycemic effects.
Read the full Spinach Extract + Empagliflozin, Metformin interactionEmpagliflozin, Metformin HydrochlorideSynjardy XR
How Empagliflozin, Metformin Hydrochloride interacts with Spinach Extract — through 1 ingredient. Tap an ingredient for the detail:
Spinach ExtractAntidiabetes Drugs Moderate
Interaction Summary
There are claims that spinach leaves have hypoglycemic effects.
Read the full Spinach Extract + Empagliflozin, Metformin Hydrochloride interactionErtugliflozinSteglatro
How Ertugliflozin interacts with Spinach Extract — through 1 ingredient. Tap an ingredient for the detail:
Spinach ExtractAntidiabetes Drugs Moderate
Interaction Summary
There are claims that spinach leaves have hypoglycemic effects.
Read the full Spinach Extract + Ertugliflozin interactionErtugliflozin, Metformin HydrochlorideSegluromet
How Ertugliflozin, Metformin Hydrochloride interacts with Spinach Extract — through 1 ingredient. Tap an ingredient for the detail:
Spinach ExtractAntidiabetes Drugs Moderate
Interaction Summary
There are claims that spinach leaves have hypoglycemic effects.
Read the full Spinach Extract + Ertugliflozin, Metformin Hydrochloride interactionExenatideBydureon, Byetta
How Exenatide interacts with Spinach Extract — through 1 ingredient. Tap an ingredient for the detail:
Spinach ExtractAntidiabetes Drugs Moderate
Interaction Summary
There are claims that spinach leaves have hypoglycemic effects.
Read the full Spinach Extract + Exenatide interactionExenatide SyntheticBydureon BCISE
How Exenatide Synthetic interacts with Spinach Extract — through 1 ingredient. Tap an ingredient for the detail:
Spinach ExtractAntidiabetes Drugs Moderate
Interaction Summary
There are claims that spinach leaves have hypoglycemic effects.
Read the full Spinach Extract + Exenatide Synthetic interactionGliclazideDiamicron
How Gliclazide interacts with Spinach Extract — through 1 ingredient. Tap an ingredient for the detail:
Spinach ExtractAntidiabetes Drugs Moderate
Interaction Summary
There are claims that spinach leaves have hypoglycemic effects.
Read the full Spinach Extract + Gliclazide interactionGlimepirideAmaryl
How Glimepiride interacts with Spinach Extract — through 1 ingredient. Tap an ingredient for the detail:
Spinach ExtractAntidiabetes Drugs Moderate
Interaction Summary
There are claims that spinach leaves have hypoglycemic effects.
Read the full Spinach Extract + Glimepiride interactionGlipizideGlucotrol, Glucotrol XL
How Glipizide interacts with Spinach Extract — through 1 ingredient. Tap an ingredient for the detail:
Spinach ExtractAntidiabetes Drugs Moderate
Interaction Summary
There are claims that spinach leaves have hypoglycemic effects.
Read the full Spinach Extract + Glipizide interactionGlipizide, MetforminMetaglip
How Glipizide, Metformin interacts with Spinach Extract — through 1 ingredient. Tap an ingredient for the detail:
Spinach ExtractAntidiabetes Drugs Moderate
Interaction Summary
There are claims that spinach leaves have hypoglycemic effects.
Read the full Spinach Extract + Glipizide, Metformin interactionGlucagonBaqsimi, Glucagon
How Glucagon interacts with Spinach Extract — through 1 ingredient. Tap an ingredient for the detail:
Spinach ExtractAntidiabetes Drugs Moderate
Interaction Summary
There are claims that spinach leaves have hypoglycemic effects.
Read the full Spinach Extract + Glucagon interactionEach ingredient & the kinds of drugs it affects
For each ingredient in Spinach Extract with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.
Spinach extract
Antidiabetes Drugs
There are claims that spinach leaves have hypoglycemic effects. Evidence from clinical research suggests that consumption of a spinach-rich meal reduces post-meal blood glucose levels. Theoretically, spinach might have additive effects with antidiabetes drugs and increase the risk of hypoglycemia. Monitor blood glucose levels closely. Dose adjustments might be necessary. Some antidiabetes drugs include glimepiride (Amaryl), glyburide (DiaBeta, Glynase PresTab, Micronase), insulin, pioglitazone (Actos), rosiglitazone (Avandia), and others.
Warfarin (Coumadin)
Spinach contains vitamin K, which can interfere with the activity of warfarin.
In human research, although eating spinach with one meal does not result in coagulation test results outside the therapeutic range, daily consumption for one week necessitates dose adjustment of warfarin. Individuals using anticoagulants should consume a consistent daily amount of spinach to maintain the effect of anticoagulant therapy.
Brand information
Manufacturer and brand details for Spinach Extract, from the product label.
BulkSupplements.com
See all BulkSupplements.com products- Name
- BulkSupplements.com
- Street Address
- 7511 Eastgate Rd
- City
- Henderson
- State
- NV
- ZipCode
- 89011
- Web Address
- BulkSupplements.com
Spinach Extract by BulkSupplements.com: Common Questions
Does Spinach Extract by BulkSupplements.com interact with any medications?
How can one product interact with so many drugs?
Where does this information come from?
Is spinach extract safe during pregnancy and breastfeeding?
What does spinach extract actually do?
Can I take this if I'm on diabetes medication?
I take warfarin — is spinach extract okay?
What are the side effects?
Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
Not sure if Spinach Extract is safe with your meds?
Our pharmacists answer your medication & supplement questions — free.
Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.
The Full Monographs Behind Spinach Extract’s Ingredients
Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.
Sources & How We Checked
Spinach Extract's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.
- NIH Dietary Supplement Label Database (DSLD) — The official product label on file for this supplement.
- Natural Medicines (Therapeutic Research Center) — Evidence-graded clinical reference behind the ingredient interaction data.
Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.
The 6 references behind this product’s interaction data
Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.
Spinach 6 references
- Brinker F. Herb Contraindications and Drug Interactions. 2nd ed. Sandy, OR: Eclectic Medical Publications, 1998.
- Karlson, B., Leijd, B., and Hellstrom, K. On the influence of vitamin K-rich vegetables and wine on the effectiveness of warfarin treatment. Acta Med Scand. 1986;220(4):347-350. PubMed
- Roller, E., Meller, S., Homey, B., Ruzicka, T., and Neumann, N. J. [Contact dermatitis caused by spinach, hedge mustard and chives]. Hautarzt 2003;54(4):374-375.
- Schuller, A., Morisset, M., Maadi, F., Kolopp Sarda, M. N., Fremont, S., Parisot, L., Kanny, G., and Moneret-Vautrin, D. A. Occupational asthma due to allergy to spinach powder in a pasta factory. Allergy 2005;60(3):408-409. PubMed
- Gustafsson, K., Asp, N. G., Hagander, B., and Nyman, M. Satiety effects of spinach in mixed meals: comparison with other vegetables. Int.J.Food Sci.Nutr. 1995;46(4):327-334. PubMed
- Schreiber, J., Muller, E., Becker, W. M., Zabel, P., Schlaak, M., and Amthor, M. [Spinach powder-induced exogenous allergic alveolitis]. Pneumologie 1998;52(1):61-65.
Parts of this content are provided by the Therapeutic Research Center, LLC.
DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.
© 2021 Therapeutic Research Center, LLC