Spirulina Ingredients & Drug Interactions
by ZHOU
What is this page for?
First and foremost: checking Spirulina against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.
Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy
Spirulina is a dietary supplement by ZHOU with 2 active ingredients. Its ingredients are commonly taken for general nutrition and energy, antioxidant support, cholesterol and metabolic health.Based on those ingredients, 628 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are California grown Spirulina. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.
Check Your Meds Against Spirulina by ZHOU
Ask about any prescription or over-the-counter medication and we check it for interactions with Spirulina by ZHOU — and tell you which ingredient is responsible.
AI summaries are generated from our interaction database for education only — always confirm with your pharmacist. How we use AI
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HelloPharmacist Scorecard of Spirulina by ZHOU
Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.
What’s inside
Full disclosure
ZHOU Spirulina is a 5-ingredient supplement built around California-grown spirulina (a nutrient-dense algae) plus four active compounds extracted or derived from it: zeaxanthin and total carotenoids (plant pigments linked to eye health), chlorophyll (the green pigment in plants), gamma-linolenic acid (an omega-6 fatty acid), and C-phycocyanin (a protein pigment unique to algae). The tablet also contains inactive ingredients — cellulose, vegetable magnesium stearate, and silica — that help bind and protect the formula.
Does it work?
Moderate evidence
Evidence for zeaxanthin supports its use for age-related macular degeneration (AMD), a leading cause of vision loss in older adults, where it's rated possibly effective. For zeaxanthin's role in age-related cognitive decline and Alzheimer's disease, the evidence isn't established enough to rate.
The same holds for claims about asthma, breast cancer, and lung health. For the other active ingredients in this product — chlorophyll, C-phycocyanin, gamma-linolenic acid, and total carotenoids — the data on file rates evidence as insufficient or contains no ratings, meaning we can't confirm their effectiveness for the conditions studied.
How safe is it?
Well-documented data
Zeaxanthin is generally well tolerated at typical supplement doses. Chlorophyll is also generally well tolerated in short-term use, though high-quality long-term safety data are limited.
The most common reported side effect of oral chlorophyll is photosensitization — increased skin sensitivity to sunlight — and in rare cases, a condition resembling pseudoporphyria (blistering skin) has been reported after oral use. For pregnancy: the safety data advises against using chlorophyll — there isn't enough reliable information.
Zeaxanthin is rated likely safe in pregnancy, but supplement safety hasn't been well studied, so use caution and talk with your doctor. For breastfeeding: chlorophyll should be avoided unless your doctor advises otherwise, as safety is unknown.
Zeaxanthin food sources are fine, but concentrated supplement safety while breastfeeding hasn't been established. We hold no pregnancy or breastfeeding data for the other three ingredients.
Meds to double-check
Moderate interaction found
Before you take ZHOU Spirulina, check your medications against these types: methotrexate (especially high-dose IV forms — chlorophyll may delay its clearance), photosensitizing drugs such as certain antibiotics and NSAIDs (chlorophyll may add to photosensitivity risk, rated Moderate), and antidiabetes drugs (zeaxanthin may theoretically raise hypoglycemia risk, rated Moderate). No interactions are documented for the three ingredients we could not check.
The bottom line
Scorecard at a glanceFully disclosed formula with some supporting evidence behind its ingredients' uses. Moderate medication interactions have been identified, and safety information is well characterized.
This product may help with age-related vision loss, but it's not for everyone. If you take methotrexate, photosensitizing drugs, or antidiabetes medications, check with your pharmacist first — these interactions can be serious.
Pregnant or breastfeeding? Talk to your doctor before starting, especially about chlorophyll.
Run your medications through the checker below.
Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI
Assessment coverage: 2 of 5 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated May 22, 2021.
This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed
General information
Key facts about Spirulina, straight from the product label.
| Brand | ZHOU |
|---|---|
| Barcode (UPC) | 859805006331 |
| Net contents | 180 Tablet(s) |
| Market status | On market |
| Date entered into DSLD | May 22, 2021 |
| DSLD ID | 250138 |
| Product type | Non-nutrient/non-botanical |
| Supplement form | Tablet Or Pill |
| Dietary claims / uses | All Other, Structure/Function |
| Intended target group(s) | Adult (18 - 50 Years) |
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.
Supplement Facts
The label details for Spirulina by ZHOU, sourced from the NIH Dietary Supplement Label Database.
Supplement Facts
| Ingredient | Amount | % DV |
|---|---|---|
| Zeaxanthin | 2.9 mg | -- |
| Chlorophyll | 30 mg | -- |
| C-Phycocyanin | 185 mg | -- |
| Gamma-Linolenic Acid | 30 mg | -- |
| Protein | 2 Gram(s) | 4% |
| Total Carotenoids | 11 mg | -- |
| California grown Spirulina | 3 Gram(s) | -- |
Other ingredients: Cellulose, Vegetable Magnesium Stearate, Silica
Tap any ingredient to jump to its full detail below.
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
General Statements
Greatness by Nature
Long live you #howizhou Facebook Instagram
Formulation
Sustainably grown in California
Pesticides & herbicides free Made with Non-GMO ingredients
California grown Longevity superfood
Energy & vitality support
Suggested/Recommended/Usage/Directions
Suggested Use: Supplement a healthy diet with 6 spirulina tablets (1 serving) per day.
Precautions
Caution: Do not exceed recommended dose.
Pregnant or nursing mothers, children under 18 and individuals with a known medical condition should consult a physician before using this or any dietary supplement.
Pregnant or nursing mothers, children under 18 and individuals with a known medical condition should consult a physician before using this or any dietary supplement.
Keep out of reach of children.
Do not use if safety seal is damaged or missing.
Seals/Symbols
GMP Good Manufacturing Practice Consistent quality Pesticides & herbicides free Made with Non-GMO ingredients
Storage
Store in a cool, dry place.
FDA Disclaimer Statement
These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.
FDA Statement of Identity
Dietary Supplement
Is this label outdated? Report a formula or label change and our pharmacy team will review it.
Spirulina by ZHOU label
The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.
Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.
View the full label (PDF)The Ingredients in Spirulina by ZHOU
These are the 2 active ingredients this product is made of. Select any to open its full monograph.
Serving size6 Tablet(s) Dosage formTablet Or Pill Servings per container30 Amounts shown are per serving.
Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.
Protein
California grown Spirulina
Interacts with327 drugs
Blue-green algae are nutrient-rich aquatic microorganisms (such as spirulina and Klamath Lake algae) taken as a supplement for energy, nutrition, and...
California grown Spirulina monograph & interactions- › Zeaxanthin
- › Chlorophyll
- › C-Phycocyanin
- › Gamma-Linolenic Acid
- › Total Carotenoids
Other (inactive) ingredients: Cellulose, Vegetable Magnesium Stearate, Silica. These complete the product’s ingredient list but are not active constituents.
Spirulina by ZHOU Drug Interactions
HelloPharmacist Interaction Report
ZHOU Spirulina contains ingredients with documented interactions affecting multiple medications.
The most serious concern is chlorophyll, which may slow the clearance of methotrexate (a cancer and autoimmune drug), potentially raising its levels in your blood to unsafe amounts. In one case report, a patient's methotrexate clearance was delayed during chlorophyll use but returned to normal once chlorophyll was stopped before treatment.
Read the full breakdown — every affected drug type, severity by severity
Chlorophyll also interacts with photosensitizing drugs (medications that make your skin react to sunlight, such as certain antibiotics and anti-inflammatory drugs) — taking them together may increase your risk of severe sunburn or skin reactions. Additionally, zeaxanthin may theoretically increase the risk of low blood sugar (hypoglycemia) if you take antidiabetes drugs, though dietary sources don't appear to carry this risk.
We could not check three other ingredients in this product: C-Phycocyanin, Gamma-Linolenic Acid, and Total Carotenoids — no interaction data is on file for them. Altogether, these interactions span 410 individual medications.
Please use the medication checker on this page to look up your exact prescriptions before you start.
Check your own medications below · Editorial policy · How we use AI
Want to check YOUR meds against Spirulina?
Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.
Go to the checkerIngredients driving the most interactions
Individual Drug Interactions
The ingredients in Spirulina interact with 628 drugs. Click any drug to see the details.
1 of the 2 ingredients in Spirulina interact with drugs. Each result below shows which ingredient is responsible. California grown Spirulina
Anacaulase-bcdbNexoBrid
How Anacaulase-bcdb interacts with Spirulina — through 1 ingredient. Tap an ingredient for the detail:
California Grown SpirulinaAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, spirulina blue-green algae might increase the risk of bleeding if used with other anticoagulant or antiplatelet drugs.
Read the full California Grown Spirulina + Anacaulase-bcdb interactionAnagrelideAgrylin
How Anagrelide interacts with Spirulina — through 1 ingredient. Tap an ingredient for the detail:
California Grown SpirulinaAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, spirulina blue-green algae might increase the risk of bleeding if used with other anticoagulant or antiplatelet drugs.
Read the full California Grown Spirulina + Anagrelide interactionAnifrolumab-fniaSaphnelo
How Anifrolumab-fnia interacts with Spirulina — through 1 ingredient. Tap an ingredient for the detail:
California Grown SpirulinaImmunosuppressants Moderate
Interaction Summary
Theoretically, concurrent use of blue-green algae might interfere with immunosuppressive therapy.
Read the full California Grown Spirulina + Anifrolumab-fnia interactionAnisindioneMiradon
How Anisindione interacts with Spirulina — through 1 ingredient. Tap an ingredient for the detail:
California Grown SpirulinaAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, spirulina blue-green algae might increase the risk of bleeding if used with other anticoagulant or antiplatelet drugs.
Read the full California Grown Spirulina + Anisindione interactionAntidiabetes, Dipeptidyl Peptidase-4 (dpp-iv) InhibitorGlyxambi
How Antidiabetes, Dipeptidyl Peptidase-4 (dpp-iv) Inhibitor interacts with Spirulina — through 2 ingredients. Tap an ingredient for the detail:
California Grown SpirulinaAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, taking blue-green algae with antidiabetes drugs might increase the risk of hypoglycemia.
Read the full California Grown Spirulina + Antidiabetes, Dipeptidyl Peptidase-4 (dpp-iv) Inhibitor interactionZeaxanthinAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, taking zeaxanthin with antidiabetes drugs might increase the risk of hypoglycemia.
Read the full Zeaxanthin + Antidiabetes, Dipeptidyl Peptidase-4 (dpp-iv) Inhibitor interactionAntithrombin IiiThrombate III
How Antithrombin Iii interacts with Spirulina — through 1 ingredient. Tap an ingredient for the detail:
California Grown SpirulinaAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, spirulina blue-green algae might increase the risk of bleeding if used with other anticoagulant or antiplatelet drugs.
Read the full California Grown Spirulina + Antithrombin Iii interactionAntithymocyte GlobulinThymoglobulin
How Antithymocyte Globulin interacts with Spirulina — through 1 ingredient. Tap an ingredient for the detail:
California Grown SpirulinaImmunosuppressants Moderate
Interaction Summary
Theoretically, concurrent use of blue-green algae might interfere with immunosuppressive therapy.
Read the full California Grown Spirulina + Antithymocyte Globulin interactionApixabanEliquis
How Apixaban interacts with Spirulina — through 1 ingredient. Tap an ingredient for the detail:
California Grown SpirulinaAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, spirulina blue-green algae might increase the risk of bleeding if used with other anticoagulant or antiplatelet drugs.
Read the full California Grown Spirulina + Apixaban interactionArgatrobanArgatroban
How Argatroban interacts with Spirulina — through 1 ingredient. Tap an ingredient for the detail:
California Grown SpirulinaAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, spirulina blue-green algae might increase the risk of bleeding if used with other anticoagulant or antiplatelet drugs.
Read the full California Grown Spirulina + Argatroban interactionAripiprazoleAbilify, Abilify Maintena, Abilify Mycite
How Aripiprazole interacts with Spirulina — through 1 ingredient. Tap an ingredient for the detail:
ChlorophyllPhotosensitizing Drugs Moderate
Interaction Summary
Theoretically, concomitant use of chlorophyll with photosensitizing drugs may have additive effects.
Read the full Chlorophyll + Aripiprazole interactionAripiprazole LauroxilAristada, Aristada Initio Kit
How Aripiprazole Lauroxil interacts with Spirulina — through 1 ingredient. Tap an ingredient for the detail:
ChlorophyllPhotosensitizing Drugs Moderate
Interaction Summary
Theoretically, concomitant use of chlorophyll with photosensitizing drugs may have additive effects.
Read the full Chlorophyll + Aripiprazole Lauroxil interactionAspirinAngettes 75, ASA, Asaphen, Aspirin, Caprin, Cartia +8 more
How Aspirin interacts with Spirulina — through 1 ingredient. Tap an ingredient for the detail:
California Grown SpirulinaAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, spirulina blue-green algae might increase the risk of bleeding if used with other anticoagulant or antiplatelet drugs.
Read the full California Grown Spirulina + Aspirin interactionAspirin, Aluminum Hydroxide, Codeine Phosphate, Magnesium HydroxideAscriptin Codeine #3
How Aspirin, Aluminum Hydroxide, Codeine Phosphate, Magnesium Hydroxide interacts with Spirulina — through 1 ingredient. Tap an ingredient for the detail:
California Grown SpirulinaAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, spirulina blue-green algae might increase the risk of bleeding if used with other anticoagulant or antiplatelet drugs.
Read the full California Grown Spirulina + Aspirin, Aluminum Hydroxide, Codeine Phosphate, Magnesium Hydroxide interactionAspirin, ButalbitalAxotal
How Aspirin, Butalbital interacts with Spirulina — through 1 ingredient. Tap an ingredient for the detail:
California Grown SpirulinaAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, spirulina blue-green algae might increase the risk of bleeding if used with other anticoagulant or antiplatelet drugs.
Read the full California Grown Spirulina + Aspirin, Butalbital interactionAspirin, Butalbital, CaffeineFiorinal
How Aspirin, Butalbital, Caffeine interacts with Spirulina — through 1 ingredient. Tap an ingredient for the detail:
California Grown SpirulinaAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, spirulina blue-green algae might increase the risk of bleeding if used with other anticoagulant or antiplatelet drugs.
Read the full California Grown Spirulina + Aspirin, Butalbital, Caffeine interactionAspirin, Butalbital, Caffeine, Codeine PhosphateFiorinal w/ Codeine
How Aspirin, Butalbital, Caffeine, Codeine Phosphate interacts with Spirulina — through 1 ingredient. Tap an ingredient for the detail:
California Grown SpirulinaAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, spirulina blue-green algae might increase the risk of bleeding if used with other anticoagulant or antiplatelet drugs.
Read the full California Grown Spirulina + Aspirin, Butalbital, Caffeine, Codeine Phosphate interactionAspirin, Butalbital, Caffeine, PhenacetinMarnal
How Aspirin, Butalbital, Caffeine, Phenacetin interacts with Spirulina — through 1 ingredient. Tap an ingredient for the detail:
California Grown SpirulinaAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, spirulina blue-green algae might increase the risk of bleeding if used with other anticoagulant or antiplatelet drugs.
Read the full California Grown Spirulina + Aspirin, Butalbital, Caffeine, Phenacetin interactionAspirin, CaffeineAnacin
How Aspirin, Caffeine interacts with Spirulina — through 1 ingredient. Tap an ingredient for the detail:
California Grown SpirulinaAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, spirulina blue-green algae might increase the risk of bleeding if used with other anticoagulant or antiplatelet drugs.
Read the full California Grown Spirulina + Aspirin, Caffeine interactionAspirin, Caffeine, Codeine PhosphateAnacin w/ Codeine
How Aspirin, Caffeine, Codeine Phosphate interacts with Spirulina — through 1 ingredient. Tap an ingredient for the detail:
California Grown SpirulinaAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, spirulina blue-green algae might increase the risk of bleeding if used with other anticoagulant or antiplatelet drugs.
Read the full California Grown Spirulina + Aspirin, Caffeine, Codeine Phosphate interactionAspirin, Caffeine, Dihydrocodeine BitartrateSynalgos DC
How Aspirin, Caffeine, Dihydrocodeine Bitartrate interacts with Spirulina — through 1 ingredient. Tap an ingredient for the detail:
California Grown SpirulinaAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, spirulina blue-green algae might increase the risk of bleeding if used with other anticoagulant or antiplatelet drugs.
Read the full California Grown Spirulina + Aspirin, Caffeine, Dihydrocodeine Bitartrate interactionAspirin, Caffeine, Dover's PwdAcedoval, Dovacet
How Aspirin, Caffeine, Dover's Pwd interacts with Spirulina — through 1 ingredient. Tap an ingredient for the detail:
California Grown SpirulinaAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, spirulina blue-green algae might increase the risk of bleeding if used with other anticoagulant or antiplatelet drugs.
Read the full California Grown Spirulina + Aspirin, Caffeine, Dover's Pwd interactionAspirin, Caffeine, HydrocodoneDamason-P
How Aspirin, Caffeine, Hydrocodone interacts with Spirulina — through 1 ingredient. Tap an ingredient for the detail:
California Grown SpirulinaAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, spirulina blue-green algae might increase the risk of bleeding if used with other anticoagulant or antiplatelet drugs.
Read the full California Grown Spirulina + Aspirin, Caffeine, Hydrocodone interactionAspirin, Caffeine, Isobutylallylbarbituric Acid, PhenacetinLanorinal
How Aspirin, Caffeine, Isobutylallylbarbituric Acid, Phenacetin interacts with Spirulina — through 1 ingredient. Tap an ingredient for the detail:
California Grown SpirulinaAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, spirulina blue-green algae might increase the risk of bleeding if used with other anticoagulant or antiplatelet drugs.
Read the full California Grown Spirulina + Aspirin, Caffeine, Isobutylallylbarbituric Acid, Phenacetin interactionAspirin, Caffeine, OrphenadrineInvagesic, Invagesic Forte, Norgesic, Norgesic Forte, Orphengesic, Orphengesic Forte
How Aspirin, Caffeine, Orphenadrine interacts with Spirulina — through 1 ingredient. Tap an ingredient for the detail:
California Grown SpirulinaAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, spirulina blue-green algae might increase the risk of bleeding if used with other anticoagulant or antiplatelet drugs.
Read the full California Grown Spirulina + Aspirin, Caffeine, Orphenadrine interactionAspirin, Caffeine, Phenacetin, PropoxypheneMargesic Comp. 65
How Aspirin, Caffeine, Phenacetin, Propoxyphene interacts with Spirulina — through 1 ingredient. Tap an ingredient for the detail:
California Grown SpirulinaAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, spirulina blue-green algae might increase the risk of bleeding if used with other anticoagulant or antiplatelet drugs.
Read the full California Grown Spirulina + Aspirin, Caffeine, Phenacetin, Propoxyphene interactionAspirin, Calcium Carbonate, Magnesium Carbonate, Magnesium OxideBufferin
How Aspirin, Calcium Carbonate, Magnesium Carbonate, Magnesium Oxide interacts with Spirulina — through 1 ingredient. Tap an ingredient for the detail:
California Grown SpirulinaAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, spirulina blue-green algae might increase the risk of bleeding if used with other anticoagulant or antiplatelet drugs.
Read the full California Grown Spirulina + Aspirin, Calcium Carbonate, Magnesium Carbonate, Magnesium Oxide interactionAspirin, CarisoprodolSoma Compound
How Aspirin, Carisoprodol interacts with Spirulina — through 1 ingredient. Tap an ingredient for the detail:
California Grown SpirulinaAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, spirulina blue-green algae might increase the risk of bleeding if used with other anticoagulant or antiplatelet drugs.
Read the full California Grown Spirulina + Aspirin, Carisoprodol interactionAspirin, Carisoprodol, Codeine PhosphateSoma Compound w/ Codeine
How Aspirin, Carisoprodol, Codeine Phosphate interacts with Spirulina — through 1 ingredient. Tap an ingredient for the detail:
California Grown SpirulinaAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, spirulina blue-green algae might increase the risk of bleeding if used with other anticoagulant or antiplatelet drugs.
Read the full California Grown Spirulina + Aspirin, Carisoprodol, Codeine Phosphate interactionAspirin, Chlorpheniramine, PhenylpropanolamineAlka-Seltzer Plus Cold
How Aspirin, Chlorpheniramine, Phenylpropanolamine interacts with Spirulina — through 2 ingredients. Tap an ingredient for the detail:
California Grown SpirulinaAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, spirulina blue-green algae might increase the risk of bleeding if used with other anticoagulant or antiplatelet drugs.
Read the full California Grown Spirulina + Aspirin, Chlorpheniramine, Phenylpropanolamine interactionChlorophyllPhotosensitizing Drugs Moderate
Interaction Summary
Theoretically, concomitant use of chlorophyll with photosensitizing drugs may have additive effects.
Read the full Chlorophyll + Aspirin, Chlorpheniramine, Phenylpropanolamine interactionAspirin, Citric Acid, Sodium BicarbonateAlka-Seltzer Pain Reliever and Antacid
How Aspirin, Citric Acid, Sodium Bicarbonate interacts with Spirulina — through 1 ingredient. Tap an ingredient for the detail:
California Grown SpirulinaAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, spirulina blue-green algae might increase the risk of bleeding if used with other anticoagulant or antiplatelet drugs.
Read the full California Grown Spirulina + Aspirin, Citric Acid, Sodium Bicarbonate interactionEach ingredient & the kinds of drugs it affects
For each ingredient in Spirulina with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.
California grown Spirulina
Anticoagulant/Antiplatelet Drugs
Theoretically, spirulina blue-green algae might increase the risk of bleeding if used with other anticoagulant or antiplatelet drugs. However, this is unlikely.
Spirulina blue-green algae have shown antiplatelet and anticoagulant effects in vitro. However, one preliminary study in 24 patients receiving spirulina blue-green algae 2.3 grams daily for 2 weeks showed no effect on platelet activation or measures of clotting time.
Antidiabetes Drugs
Theoretically, taking blue-green algae with antidiabetes drugs might increase the risk of hypoglycemia.
Human research shows that spirulina blue-green algae can have hypoglycemic effects in patients with diabetes, at least some of whom were using antidiabetes drugs. However, blue-green algae does not seem to improve glycated hemoglobin (HbA1c) levels in patients with diabetes. A meta-analysis of animal studies also suggests that spirulina blue-green algae have hypoglycemic effects.
Immunosuppressants
Theoretically, concurrent use of blue-green algae might interfere with immunosuppressive therapy.
Blue-green algae have been shown to stimulate the immune system.
Brand information
Manufacturer and brand details for Spirulina, from the product label.
ZHOU
See all ZHOU products- Name
- ZHOU Nutrition Zhou, Inc.
- City
- Park City
- State
- UT
- ZipCode
- 84098
- Phone Number
- 1-855-700-9468
- Web Address
- zhounutrition.com
Spirulina by ZHOU: Common Questions
Does Spirulina by ZHOU interact with any medications?
How can one product interact with so many drugs?
Where does this information come from?
Is zeaxanthin the main reason people take this supplement?
Can I take this if I'm on diabetes medication?
What's chlorophyll doing in here?
Is this safe if I'm pregnant or breastfeeding?
Will this help my eyesight?
What are the inactive ingredients?
Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
Not sure if Spirulina is safe with your meds?
Our pharmacists answer your medication & supplement questions — free.
Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.
The Full Monographs Behind Spirulina’s Ingredients
Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.
Blue-green Algae
Interacts with 327 drugsBlue-green algae are nutrient-rich aquatic microorganisms (such as spirulina and Klamath Lake algae) taken as a supplement for energy, nutrition, and general wellness. Evidence for most heal...
Read the full Blue-green Algae monograph → Herb & supplement monographZeaxanthin
Interacts with 86 drugsZeaxanthin is a carotenoid pigment that, along with lutein, concentrates in the macula of the eye and may help support long-term eye health. The strongest evidence relates to slowing progres...
Read the full Zeaxanthin monograph → Herb & supplement monographChlorophyll
Interacts with 337 drugsChlorophyll is the green pigment found in plants and algae, and supplements often use a stable form called chlorophyllin. It is most studied for reducing body and fecal odor and as a topical...
Read the full Chlorophyll monograph →Sources & How We Checked
Spirulina's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.
- NIH Dietary Supplement Label Database (DSLD) — The official product label on file for this supplement.
- Natural Medicines (Therapeutic Research Center) — Evidence-graded clinical reference behind the ingredient interaction data.
Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.
The 31 references behind this product’s interaction data
Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.
Zeaxanthin 4 references
- Montonen J, Knekt P, Jarvinen R, Reunanen A. Dietary antioxidant intake and risk of type 2 diabetes. Diabetes Care 2004;27:362-6. PubMed
- Leermakers ET, Darweesh SK, Baena CP, et al. The effects of lutein on cardiometabolic health across the life course: a systematic review and meta-analysis. Am J Clin Nutr 2016;103(2):481-94. PubMed
- Kou L, Du M, Zhang C, Dai Z, Li X, Zhang B. The Hypoglycemic, Hypolipidemic, and Anti-Diabetic Nephritic Activities of Zeaxanthin in Diet-Streptozotocin-Induced Diabetic Sprague Dawley Rats. Appl Biochem Biotechnol 2017;182(3):944-955. PubMed
- Xu X, Zhao X, Berde Y, Low YL, Kuchan MJ. Milk and Plasma Lutein and Zeaxanthin Concentrations in Chinese Breast-Feeding Mother-Infant Dyads With Healthy Maternal Fruit and Vegetable Intake. J Am Coll Nutr 2019;38(2):179-184. PubMed
Chlorophyll 5 references
- Mathews-Roth MM. Carotenoids in erythropoietic protoporphyria and other photosensitivity diseases. Ann N Y Acad Sci, 1993; 691:127-38. PubMed
- Belen'kii, G. B. and Krikun, B. L. [Treatment of herpes simplex and herpes zoster by chlorophyll preparations]. Sov.Med. 1971;34(1):151-152.
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