Standardized Sambucus Sambucus nigra + Probiotic Ingredients & Drug Interactions
What is this page for?
First and foremost: checking Standardized Sambucus Sambucus nigra + Probiotic against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.
Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy
Standardized Sambucus Sambucus nigra + Probiotic is a dietary supplement by Nature's Answer with 5 active ingredients. Its ingredients are commonly taken for colds, flu (influenza), other respiratory infections.Based on those ingredients, 302 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Lactobacillus acidophilus, Black Elderberry (Sambucus nigra) concentrated fruit extract. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.
Check Your Meds Against Standardized Sambucus Sambucus nigra + Probiotic by Nature's Answer
Ask about any prescription or over-the-counter medication and we check it for interactions with Standardized Sambucus Sambucus nigra + Probiotic by Nature's Answer — and tell you which ingredient is responsible.
AI summaries are generated from our interaction database for education only — always confirm with your pharmacist. How we use AI
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HelloPharmacist Scorecard of Standardized Sambucus Sambucus nigra + Probiotic by Nature's Answer
Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.
What’s inside
Low disclosure
This product contains 5 active ingredients: three specific probiotic strains (Lactobacillus paracasei, Bifidobacterium animalis lactis, and Lactobacillus acidophilus), Lactobacillus rhamnosus GG, and a concentrated black elderberry fruit extract. The probiotics are live beneficial bacteria meant to support gut health, while the elderberry is included for immune support.
The rest is inactive ingredients — glycerin, hypromellose, and water — that make up the capsule.
Does it work?
Moderate evidence
The evidence for Lactobacillus acidophilus (which is one of this product's active strains) shows it's possibly effective for irritable bowel syndrome, Helicobacter pylori infection, antibiotic-associated diarrhea, and bacterial vaginosis. For atopic disease (allergic conditions), the data suggests it's possibly ineffective.
For acute respiratory distress syndrome, we don't have enough reliable evidence to rate it. We don't hold effectiveness data in our system for the other probiotic strains or the black elderberry extract in this product.
How safe is it?
Well-documented data
Lactobacillus acidophilus is generally well tolerated in healthy adults and children. That said, data are limited, so check with your doctor before starting it.
Since the product contains live organisms, there's a theoretical concern they could cause serious infection in rare cases — most documented cases involved patients whose immune systems were already compromised. Orally, the most common side effects from probiotics are mild gastrointestinal ones: epigastric discomfort, abdominal pain, indigestion, gas, bloating, diarrhea, vomiting, or burping; these are uncommon.
One clinical trial noted a couple of cases of rash and itching, though it wasn't clear whether L. acidophilus, another ingredient, or the combination was responsible.
Meds to double-check
Moderate interaction found
If you take antibiotic drugs, separate your doses from this product by a few hours — antibiotics can kill off the live probiotics and make them less effective. We couldn't check interaction data for three of the five active ingredients (the other two Lactobacillus strains and the black elderberry), so run your full medication list through the checker below before you start.
The bottom line
Scorecard at a glanceFormula with limited ingredient disclosure with some supporting evidence for its stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.
This could be worth trying if you have irritable bowel syndrome, need gut support during or after antibiotics, or are interested in general probiotic supplementation. If you're on antibiotics, space them several hours apart from this product.
Definitely check your medications with our tool before you start, and talk to your pharmacist if you have a weakened immune system or other health concerns.
Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI
Assessment coverage: 2 of 5 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Jul 24, 2019.
This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed
General information
Key facts about Standardized Sambucus Sambucus nigra + Probiotic, straight from the product label.
| Brand | Nature's Answer |
|---|---|
| Barcode (UPC) | 083000262654 |
| Net contents | 60 Vegan DuoCap Capsules |
| Market status | On market |
| Date entered into DSLD | Jul 24, 2019 |
| DSLD ID | 204353 |
| Product type | Other Combinations |
| Supplement form | Capsule |
| Dietary claims / uses | All Other, Structure/Function |
| Intended target group(s) | Adult (18 - 50 Years), Gluten Free |
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.
Supplement Facts
The label details for Standardized Sambucus Sambucus nigra + Probiotic by Nature's Answer, sourced from the NIH Dietary Supplement Label Database.
Supplement Facts
| Ingredient | Amount | % DV |
|---|---|---|
| Lactobacillus paracasei | 0 NP | -- |
| Bifidobacterium animalis lactis | 0 NP | -- |
| Lactobacillus acidophilus | 0 NP | -- |
| Lactobacillus rhamnosus GG | 0 NP | -- |
| Black Elderberry (Sambucus nigra) concentrated fruit extract | 100 mg | -- |
| Immunity Probiotic Blend containing | 0 NP | -- |
Other ingredients: Glycerin, Hypromellose, Water
Tap any ingredient to jump to its full detail below.
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
General Statements
2 in 1 DuoCap technology
Moisture defense maintains the integrity of the Immune Probiotic
Internal + external barrier for enhanced probiotic stability Immune probiotic protected inside inner capsule
New Since 1972
Formula
Elderberry extract + Immune Probiotic
Liquid Elderberry extract in outer capsule
Per serving 32,000 mg (32 g) fresh Elderberry 10 billion CFU Probiotic
FDA Disclaimer Statement
These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.
Seals/Symbols
Holistically Balanced
Cruelty Free Not Tested On Animals
Non GMO
Gluten Free
Formulation
Non GMO Gluten Free
Absolutely no preservatives
FDA Statement of Identity
Dietary Supplement
Suggested/Recommended/Usage/Directions
Suggested use: As a dietary supplement, take 2 capsules per day with food or water.
Brand IP Statement(s)
VCaps and DuoCap are trademarks of Lonza or its affiliates.
Precautions
Warning: Keep out of reach of children.
Do not use if safety seal is damaged or missing.
If you are pregnant, nursing, taking any medications, planning any medical procedure or have a medical condition, consult with your healthcare practitioner before use.
Storage
Store in a cool, dry place.
Is this label outdated? Report a formula or label change and our pharmacy team will review it.
Standardized Sambucus Sambucus nigra + Probiotic by Nature's Answer label
The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.
Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.
View the full label (PDF)The Ingredients in Standardized Sambucus Sambucus nigra + Probiotic by Nature's Answer
These are the 5 active ingredients this product is made of. Select any to open its full monograph.
Serving size2 VCaps Plus Capsule(s) Dosage formCapsule Servings per container30 Amounts shown are per serving.
Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.
Black Elderberry (Sambucus nigra) concentrated fruit extract
Interacts with121 drugs
Elderberry is a popular herbal supplement, mainly taken to help with colds and flu. Some small studies suggest it may modestly shorten cold or flu sym...
Black Elderberry (Sambucus nigra) concentrated fruit extract monograph & interactionsImmunity Probiotic Blend containing
- › Lactobacillus paracasei
- › Bifidobacterium animalis lactis
- › Lactobacillus acidophilus
- › Lactobacillus rhamnosus GG
Other (inactive) ingredients: Glycerin, Hypromellose, Water. These complete the product’s ingredient list but are not active constituents.
Standardized Sambucus Sambucus nigra + Probiotic by Nature's Answer Drug Interactions
HelloPharmacist Interaction Report
Nature's Answer Standardized Sambucus Sambucus nigra + Probiotic contains five active ingredients, and we've found documented interactions with one of them.
Lactobacillus acidophilus may reduce the effectiveness of antibiotic drugs (a Moderate interaction) because antibiotics can kill the live organisms in the probiotic. If you're on an antibiotic, timing matters — separate doses by a few hours when you can.
Read the full breakdown — every affected drug type, severity by severity
We couldn't check the interaction data for Lactobacillus paracasei, Bifidobacterium animalis lactis, Lactobacillus rhamnosus GG, or the black elderberry extract — we don't hold monographs for those ingredients, so we can't tell you whether they interact with your medications. Altogether, these interactions span 182 individual medications.
Use the medication checker on this page to look up your exact drugs, especially if you're taking antibiotics.
Check your own medications below · Editorial policy · How we use AI
Want to check YOUR meds against Standardized Sambucus Sambucus nigra + Probiotic?
Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.
Go to the checkerIngredients driving the most interactions
Individual Drug Interactions
The ingredients in Standardized Sambucus Sambucus nigra + Probiotic interact with 302 drugs. Click any drug to see the details.
2 of the 5 ingredients in Standardized Sambucus Sambucus nigra + Probiotic interact with drugs. Each result below shows which ingredient is responsible. Lactobacillus acidophilus Black Elderberry (Sambucus nigra) concentrated fruit extract
6-mercaptopurinePurinethol
How 6-mercaptopurine interacts with Standardized Sambucus Sambucus nigra + Probiotic — through 1 ingredient. Tap an ingredient for the detail:
Black Elderberry (sambucus Nigra) Concentrated Fruit ExtractImmunosuppressants Moderate
Interaction Summary
Theoretically, elderberry might interfere with immunosuppressant therapy due to its immunostimulant activity.
Read the full Black Elderberry (sambucus Nigra) Concentrated Fruit Extract + 6-mercaptopurine interactionAbrocitinibCibinqo
How Abrocitinib interacts with Standardized Sambucus Sambucus nigra + Probiotic — through 1 ingredient. Tap an ingredient for the detail:
Black Elderberry (sambucus Nigra) Concentrated Fruit ExtractImmunosuppressants Moderate
Interaction Summary
Theoretically, elderberry might interfere with immunosuppressant therapy due to its immunostimulant activity.
Read the full Black Elderberry (sambucus Nigra) Concentrated Fruit Extract + Abrocitinib interactionAdalimumabHumira
How Adalimumab interacts with Standardized Sambucus Sambucus nigra + Probiotic — through 1 ingredient. Tap an ingredient for the detail:
Black Elderberry (sambucus Nigra) Concentrated Fruit ExtractImmunosuppressants Moderate
Interaction Summary
Theoretically, elderberry might interfere with immunosuppressant therapy due to its immunostimulant activity.
Read the full Black Elderberry (sambucus Nigra) Concentrated Fruit Extract + Adalimumab interactionAdalimumab-adazHyrimoz
How Adalimumab-adaz interacts with Standardized Sambucus Sambucus nigra + Probiotic — through 1 ingredient. Tap an ingredient for the detail:
Black Elderberry (sambucus Nigra) Concentrated Fruit ExtractImmunosuppressants Moderate
Interaction Summary
Theoretically, elderberry might interfere with immunosuppressant therapy due to its immunostimulant activity.
Read the full Black Elderberry (sambucus Nigra) Concentrated Fruit Extract + Adalimumab-adaz interactionAdalimumab-adbmCyltezo
How Adalimumab-adbm interacts with Standardized Sambucus Sambucus nigra + Probiotic — through 1 ingredient. Tap an ingredient for the detail:
Black Elderberry (sambucus Nigra) Concentrated Fruit ExtractImmunosuppressants Moderate
Interaction Summary
Theoretically, elderberry might interfere with immunosuppressant therapy due to its immunostimulant activity.
Read the full Black Elderberry (sambucus Nigra) Concentrated Fruit Extract + Adalimumab-adbm interactionAdalimumab-afzbAbrilada
How Adalimumab-afzb interacts with Standardized Sambucus Sambucus nigra + Probiotic — through 1 ingredient. Tap an ingredient for the detail:
Black Elderberry (sambucus Nigra) Concentrated Fruit ExtractImmunosuppressants Moderate
Interaction Summary
Theoretically, elderberry might interfere with immunosuppressant therapy due to its immunostimulant activity.
Read the full Black Elderberry (sambucus Nigra) Concentrated Fruit Extract + Adalimumab-afzb interactionAdalimumab-attoAmjevita
How Adalimumab-atto interacts with Standardized Sambucus Sambucus nigra + Probiotic — through 1 ingredient. Tap an ingredient for the detail:
Black Elderberry (sambucus Nigra) Concentrated Fruit ExtractImmunosuppressants Moderate
Interaction Summary
Theoretically, elderberry might interfere with immunosuppressant therapy due to its immunostimulant activity.
Read the full Black Elderberry (sambucus Nigra) Concentrated Fruit Extract + Adalimumab-atto interactionAdalimumab-bwwdHadlima
How Adalimumab-bwwd interacts with Standardized Sambucus Sambucus nigra + Probiotic — through 1 ingredient. Tap an ingredient for the detail:
Black Elderberry (sambucus Nigra) Concentrated Fruit ExtractImmunosuppressants Moderate
Interaction Summary
Theoretically, elderberry might interfere with immunosuppressant therapy due to its immunostimulant activity.
Read the full Black Elderberry (sambucus Nigra) Concentrated Fruit Extract + Adalimumab-bwwd interactionAdalimumab-fkjpHulio
How Adalimumab-fkjp interacts with Standardized Sambucus Sambucus nigra + Probiotic — through 1 ingredient. Tap an ingredient for the detail:
Black Elderberry (sambucus Nigra) Concentrated Fruit ExtractImmunosuppressants Moderate
Interaction Summary
Theoretically, elderberry might interfere with immunosuppressant therapy due to its immunostimulant activity.
Read the full Black Elderberry (sambucus Nigra) Concentrated Fruit Extract + Adalimumab-fkjp interactionAlefaceptAmevive
How Alefacept interacts with Standardized Sambucus Sambucus nigra + Probiotic — through 1 ingredient. Tap an ingredient for the detail:
Black Elderberry (sambucus Nigra) Concentrated Fruit ExtractImmunosuppressants Moderate
Interaction Summary
Theoretically, elderberry might interfere with immunosuppressant therapy due to its immunostimulant activity.
Read the full Black Elderberry (sambucus Nigra) Concentrated Fruit Extract + Alefacept interactionAlemtuzumabCampath
How Alemtuzumab interacts with Standardized Sambucus Sambucus nigra + Probiotic — through 1 ingredient. Tap an ingredient for the detail:
Black Elderberry (sambucus Nigra) Concentrated Fruit ExtractImmunosuppressants Moderate
Interaction Summary
Theoretically, elderberry might interfere with immunosuppressant therapy due to its immunostimulant activity.
Read the full Black Elderberry (sambucus Nigra) Concentrated Fruit Extract + Alemtuzumab interactionAmikacinAmikin, Arikayce
How Amikacin interacts with Standardized Sambucus Sambucus nigra + Probiotic — through 1 ingredient. Tap an ingredient for the detail:
Lactobacillus AcidophilusAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Lactobacillus acidophilus with antibiotic drugs might decrease the effectiveness of L.
Read the full Lactobacillus Acidophilus + Amikacin interactionAmoxicillinAmix, Amoram, Amoxident, Amoxil Capsules, Amoxil Injection, Galenamox +3 more
How Amoxicillin interacts with Standardized Sambucus Sambucus nigra + Probiotic — through 1 ingredient. Tap an ingredient for the detail:
Lactobacillus AcidophilusAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Lactobacillus acidophilus with antibiotic drugs might decrease the effectiveness of L.
Read the full Lactobacillus Acidophilus + Amoxicillin interactionAmoxicillin VeterinaryBiomox
How Amoxicillin Veterinary interacts with Standardized Sambucus Sambucus nigra + Probiotic — through 1 ingredient. Tap an ingredient for the detail:
Lactobacillus AcidophilusAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Lactobacillus acidophilus with antibiotic drugs might decrease the effectiveness of L.
Read the full Lactobacillus Acidophilus + Amoxicillin Veterinary interactionAmoxicillin, Clavulanate PotassiumAugmentin, Augmentin '125/31 SF', Augmentin '250/62 SF', Augmentin XR, Augmentin-Duo 400/57, Clavulin
How Amoxicillin, Clavulanate Potassium interacts with Standardized Sambucus Sambucus nigra + Probiotic — through 1 ingredient. Tap an ingredient for the detail:
Lactobacillus AcidophilusAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Lactobacillus acidophilus with antibiotic drugs might decrease the effectiveness of L.
Read the full Lactobacillus Acidophilus + Amoxicillin, Clavulanate Potassium interactionAmoxicillin, Omeprazole Magnesium, RifabutinTalicia
How Amoxicillin, Omeprazole Magnesium, Rifabutin interacts with Standardized Sambucus Sambucus nigra + Probiotic — through 1 ingredient. Tap an ingredient for the detail:
Lactobacillus AcidophilusAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Lactobacillus acidophilus with antibiotic drugs might decrease the effectiveness of L.
Read the full Lactobacillus Acidophilus + Amoxicillin, Omeprazole Magnesium, Rifabutin interactionAmphotericin, TetracyclineMysteclin-F
How Amphotericin, Tetracycline interacts with Standardized Sambucus Sambucus nigra + Probiotic — through 1 ingredient. Tap an ingredient for the detail:
Lactobacillus AcidophilusAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Lactobacillus acidophilus with antibiotic drugs might decrease the effectiveness of L.
Read the full Lactobacillus Acidophilus + Amphotericin, Tetracycline interactionAmpicillinOmnipen, Omnipen-N, Penbritin, Principen, Rimacillin
How Ampicillin interacts with Standardized Sambucus Sambucus nigra + Probiotic — through 1 ingredient. Tap an ingredient for the detail:
Lactobacillus AcidophilusAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Lactobacillus acidophilus with antibiotic drugs might decrease the effectiveness of L.
Read the full Lactobacillus Acidophilus + Ampicillin interactionAmpicillin, SulbactamUnasyn
How Ampicillin, Sulbactam interacts with Standardized Sambucus Sambucus nigra + Probiotic — through 1 ingredient. Tap an ingredient for the detail:
Lactobacillus AcidophilusAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Lactobacillus acidophilus with antibiotic drugs might decrease the effectiveness of L.
Read the full Lactobacillus Acidophilus + Ampicillin, Sulbactam interactionAnifrolumab-fniaSaphnelo
How Anifrolumab-fnia interacts with Standardized Sambucus Sambucus nigra + Probiotic — through 1 ingredient. Tap an ingredient for the detail:
Black Elderberry (sambucus Nigra) Concentrated Fruit ExtractImmunosuppressants Moderate
Interaction Summary
Theoretically, elderberry might interfere with immunosuppressant therapy due to its immunostimulant activity.
Read the full Black Elderberry (sambucus Nigra) Concentrated Fruit Extract + Anifrolumab-fnia interactionAntithymocyte GlobulinThymoglobulin
How Antithymocyte Globulin interacts with Standardized Sambucus Sambucus nigra + Probiotic — through 1 ingredient. Tap an ingredient for the detail:
Black Elderberry (sambucus Nigra) Concentrated Fruit ExtractImmunosuppressants Moderate
Interaction Summary
Theoretically, elderberry might interfere with immunosuppressant therapy due to its immunostimulant activity.
Read the full Black Elderberry (sambucus Nigra) Concentrated Fruit Extract + Antithymocyte Globulin interactionAtezolizumabTecentriq
How Atezolizumab interacts with Standardized Sambucus Sambucus nigra + Probiotic — through 1 ingredient. Tap an ingredient for the detail:
Black Elderberry (sambucus Nigra) Concentrated Fruit ExtractImmunosuppressants Moderate
Interaction Summary
Theoretically, elderberry might interfere with immunosuppressant therapy due to its immunostimulant activity.
Read the full Black Elderberry (sambucus Nigra) Concentrated Fruit Extract + Atezolizumab interactionAvibactam Sodium, CeftazidimeAvycaz
How Avibactam Sodium, Ceftazidime interacts with Standardized Sambucus Sambucus nigra + Probiotic — through 1 ingredient. Tap an ingredient for the detail:
Lactobacillus AcidophilusAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Lactobacillus acidophilus with antibiotic drugs might decrease the effectiveness of L.
Read the full Lactobacillus Acidophilus + Avibactam Sodium, Ceftazidime interactionAzamuneImmunoprin
How Azamune interacts with Standardized Sambucus Sambucus nigra + Probiotic — through 1 ingredient. Tap an ingredient for the detail:
Black Elderberry (sambucus Nigra) Concentrated Fruit ExtractImmunosuppressants Moderate
Interaction Summary
Theoretically, elderberry might interfere with immunosuppressant therapy due to its immunostimulant activity.
Read the full Black Elderberry (sambucus Nigra) Concentrated Fruit Extract + Azamune interactionAzathioprineAzamune, Imuran
How Azathioprine interacts with Standardized Sambucus Sambucus nigra + Probiotic — through 1 ingredient. Tap an ingredient for the detail:
Black Elderberry (sambucus Nigra) Concentrated Fruit ExtractImmunosuppressants Moderate
Interaction Summary
Theoretically, elderberry might interfere with immunosuppressant therapy due to its immunostimulant activity.
Read the full Black Elderberry (sambucus Nigra) Concentrated Fruit Extract + Azathioprine interactionAzithromycinAzasite, Zithromax, Zmax
How Azithromycin interacts with Standardized Sambucus Sambucus nigra + Probiotic — through 1 ingredient. Tap an ingredient for the detail:
Lactobacillus AcidophilusAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Lactobacillus acidophilus with antibiotic drugs might decrease the effectiveness of L.
Read the full Lactobacillus Acidophilus + Azithromycin interactionAztreonamAzactam
How Aztreonam interacts with Standardized Sambucus Sambucus nigra + Probiotic — through 1 ingredient. Tap an ingredient for the detail:
Lactobacillus AcidophilusAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Lactobacillus acidophilus with antibiotic drugs might decrease the effectiveness of L.
Read the full Lactobacillus Acidophilus + Aztreonam interactionBacampicillinPenglobe
How Bacampicillin interacts with Standardized Sambucus Sambucus nigra + Probiotic — through 1 ingredient. Tap an ingredient for the detail:
Lactobacillus AcidophilusAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Lactobacillus acidophilus with antibiotic drugs might decrease the effectiveness of L.
Read the full Lactobacillus Acidophilus + Bacampicillin interactionBacitracinBaci-IM, Baciguent, Bacitracin Ointment
How Bacitracin interacts with Standardized Sambucus Sambucus nigra + Probiotic — through 1 ingredient. Tap an ingredient for the detail:
Lactobacillus AcidophilusAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Lactobacillus acidophilus with antibiotic drugs might decrease the effectiveness of L.
Read the full Lactobacillus Acidophilus + Bacitracin interactionBasiliximabSimulect
How Basiliximab interacts with Standardized Sambucus Sambucus nigra + Probiotic — through 1 ingredient. Tap an ingredient for the detail:
Black Elderberry (sambucus Nigra) Concentrated Fruit ExtractImmunosuppressants Moderate
Interaction Summary
Theoretically, elderberry might interfere with immunosuppressant therapy due to its immunostimulant activity.
Read the full Black Elderberry (sambucus Nigra) Concentrated Fruit Extract + Basiliximab interactionEach ingredient & the kinds of drugs it affects
For each ingredient in Standardized Sambucus Sambucus nigra + Probiotic with known interactions, here are the types of medications they can affect. Open any type for the detail — or search your exact drug in the checker above.
Lactobacillus acidophilus
Antibiotic Drugs
Theoretically, taking Lactobacillus acidophilus with antibiotic drugs might decrease the effectiveness of L. acidophilus.
L. acidophilus preparations usually contain live and active organisms. Therefore, simultaneously taking antibiotics might kill a significant number of the organisms. Tell patients to separate administration of antibiotics and L. acidophilus preparations by at least two hours.
Black Elderberry (Sambucus nigra) concentrated fruit extract
Immunosuppressants
Theoretically, elderberry might interfere with immunosuppressant therapy due to its immunostimulant activity.
Elderberry has immunostimulant activity, increasing the production of cytokines, including interleukin and tumor necrosis factor.
Pazopanib (Votrient)
Theoretically, elderberry might interact with pazopanib, potentially increasing the risk of adverse effects.
Brand information
Manufacturer and brand details for Standardized Sambucus Sambucus nigra + Probiotic, from the product label.
Nature's Answer
See all Nature's Answer products- Name
- Nature's Answer
- Street Address
- 85 Commerce Drive
- City
- Hauppauge
- State
- NY
- ZipCode
- 11788
- Phone Number
- (800) 439-2324
- Web Address
- www.naturesanswer.com
Standardized Sambucus Sambucus nigra + Probiotic by Nature's Answer: Common Questions
Does Standardized Sambucus Sambucus nigra + Probiotic by Nature's Answer interact with any medications?
How can one product interact with so many drugs?
Where does this information come from?
Can I take this while I'm on an antibiotic?
What probiotics are in this?
Does this product have any fillers?
Is this effective for IBS?
Are there any common side effects?
Is this safe if my immune system is weak?
Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
Not sure if Standardized Sambucus Sambucus nigra + Probiotic is safe with your meds?
Our pharmacists answer your medication & supplement questions — free.
Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.
The Full Monographs Behind Standardized Sambucus Sambucus nigra + Probiotic’s Ingredients
Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.
Elderberry
Interacts with 121 drugsElderberry is a popular herbal supplement, mainly taken to help with colds and flu. Some small studies suggest it may modestly shorten cold or flu symptoms, but the evidence is limited and n...
Read the full Elderberry monograph → Herb & supplement monographLactobacillus Acidophilus
Interacts with 182 drugsLactobacillus acidophilus is a 'friendly' bacterium used as a probiotic to support gut and vaginal health. It is generally well tolerated in healthy people, and there is reasonable evidence...
Read the full Lactobacillus Acidophilus monograph →Sources & How We Checked
Standardized Sambucus Sambucus nigra + Probiotic's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.
- NIH Dietary Supplement Label Database (DSLD) — The official product label on file for this supplement.
- Natural Medicines (Therapeutic Research Center) — Evidence-graded clinical reference behind the ingredient interaction data.
Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.
The 21 references behind this product’s interaction data
Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.
Lactobacillus Acidophilus 15 references
- Pierce A. The American Pharmaceutical Association Practical Guide to Natural Medicines. New York: The Stonesong Press, 1999:19.
- Begtrup LM, de Muckadell OB, Kjeldsen J, Christensen RD, Jarbøl DE. Long-term treatment with probiotics in primary care patients with irritable bowel syndrome--a randomised, double-blind, placebo controlled trial. Scand J Gastroenterol 2013;48(10):1127-35 PubMed
- Chatterjee S, Kar P, Das T, Ray S, Gangulyt S, Rajendiran C, Mitra M. Randomised placebo-controlled double blind multicentric trial on efficacy and safety of Lactobacillus acidophilus LA-5 and Bifidobacterium BB-12 for prevention of antibiotic-associated
- Shavakhi A, Tabesh E, Yaghoutkar A, Hashemi H, Tabesh F, Khodadoostan M,Minakari M, Shavakhi S, Gholamrezaei A. The effects of multistrain probiotic compound on bismuth-containing quadruple therapy for Helicobacter pylori infection: a randomized placebo-c
- Karamali M, Dadkhah F, Sadrkhanlou M, et al. Effects of probiotic supplementation on glycaemic control and lipid profiles in gestational diabetes: a randomized, double-blind, placebo-controlled trial. Diabetes Metab 2016;42(4):234-41. PubMed
- Badehnoosh B, Karamali M, Zarrati M, et al. The effects of probiotic supplementation on biomarkers of inflammation, oxidative stress and pregnancy outcomes in gestational diabetes. J Matern Fetal Neonatal Med. 2018 May;31(9):1128-1136.
- Kumar S, Kumar R, Rohilla L, Jacob N, Yadav J, Sachdeva N. A high potency multi-strain probiotic improves glycemic control in children with new-onset type 1 diabetes mellitus: A randomized, double-blind, and placebo-controlled pilot study. Pediatr Diabete
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- Sadrin S, Sennoune S, Gout B, et al. A 2-strain mixture of Lactobacillus acidophilus in the treatment of irritable bowel syndrome: A placebo-controlled randomized clinical trial. Dig Liver Dis 2020;52(5):534-540. PubMed
- Stoffer JN, Slingsby TJ, Giuliari GP. Lactobacillus acidophilus endophthalmitis after intravitreal bevacizumab injection requiring intraocular lens explantation. Can J Ophthalmol 2022;57(1):e21-e22. PubMed
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See these in context on the Lactobacillus Acidophilus monograph →
Elderberry 6 references
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- Elderberry (Sambucus species). The Poison Plant Patch, Novia Scotia Museum, 2007. Available at: http://museum.gov.ns.ca/poison/?section=species&id=117 (Accessed 16 October 2009).
- European elder. Canadian Poisonous Plants Information System. Available at: http://www.cbif.gc.ca/pls/pp/ppack.jump?p_null=all&p_psn=121&p_type=all&p_sci=comm&p_x=px (Accessed 16 October 2009).
- Raus K, Pleschka S, Klein P, Schoop R, Fisher P. Effect of an echinacea-based hot drink versus oseltamivir in Influenza treatment: a randomized, double-blind, double-dummy, multicenter, noninferiority clinical trial. . Curr Ther Res Clin Exp. 2015;20;77:6 PubMed
- Ramachandran A, Antala D, Pudasainee P, Panginikkod S, Gupta H. A Plausible Association Between the Use of Elderberry and Autoimmune Hepatitis. Cureus 2022;14(4):e24250. PubMed
- Agarwal N, Mangla A. Elderberry interaction with pazopanib in a patient with soft-tissue sarcoma: A case report and literature review. Mol Clin Oncol 2024;20(5):36. PubMed
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