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Dietary supplement

Stevia Ingredients & Drug Interactions

by plnt

Stevia label
See full label image
Liquid Category: Botanical
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 16, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Stevia against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Stevia is a dietary supplement by plnt with 1 active ingredient. Its ingredients are commonly taken for sugar substitute / sweetener, blood sugar support in diabetes, weight management.Based on those ingredients, 259 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Stevia leaf extract. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

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Check Your Meds Against Stevia by plnt

Ask about any prescription or over-the-counter medication and we check it for interactions with Stevia by plnt — and tell you which ingredient is responsible.

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HelloPharmacist Scorecard of Stevia by plnt

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Jul 11, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

This product has one active ingredient: stevia leaf extract, a natural sweetener derived from the stevia plant. It's suspended in vegetable glycerin and deionized water.

Purified stevia sweeteners (like the stevioside and steviol glycosides in this extract) are commonly used in food and beverages. This liquid form lets you add a small amount to drinks or recipes without the bulk of powder.

Does it work?

Couldn't assess
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not assessable

This is a single-ingredient Stevia product and its label doesn't state a use — see Stevia's own graded uses on its monograph.

Why this rating?
  • We looked at the product name, claims, and label statements and couldn't find a stated purpose to grade.

The evidence for stevia's effects on blood sugar, blood pressure, and weight loss is limited. We hold ratings of insufficient reliable evidence for all three uses — meaning the data we have isn't strong enough to say whether it works or doesn't.

Some small studies hint it may lower blood sugar briefly after meals, but other research hasn't confirmed a meaningful effect. If you're considering stevia for any of these purposes, talk with your doctor or pharmacist about what the current evidence actually supports.

The evidence, ingredient by ingredient Stevia

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Purified stevia sweeteners at typical food amounts are generally recognized as safe by regulatory agencies. However, the safety data for whole-leaf stevia or high-dose supplements is limited, so use caution with larger amounts like you'd find in supplement form.

When taken by mouth, stevia and its active compounds are usually well tolerated. The most common side effects — bloating, dizziness, headache, muscle pain, nausea, and numbness — tend to be minor and often clear up after the first week.

Serious allergic reactions are rare. We hold no pregnancy or breastfeeding safety data for this ingredient on file.

Side effects, ingredient by ingredient Stevia

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Stevia.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: diabetes medications; lithium.
  • For scale: 259 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before you use this stevia product, double-check if you take lithium (Moderate risk of higher blood levels), any blood pressure medication (Minor risk of added blood-pressure drop), or any diabetes drug (Minor risk of added blood-sugar lowering). Use our medication checker below with your exact drugs.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with no assessable stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.

Stevia is a natural sweetener that's generally well tolerated at typical doses. If you take lithium, blood pressure medication, or diabetes drugs, check your specific medications with our tool before starting — the interactions are real, though often theoretical.

Talk with your pharmacist about whether this product fits your routine.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Nov 21, 2019.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Stevia, straight from the product label.

Brand plnt
Barcode (UPC) 766536024933
Net contents 4 fl. Oz.; 118 mL
Market status On market
Date entered into DSLD Nov 21, 2019
DSLD ID 208938
Product type Botanical
Supplement form Liquid
Dietary claims / uses All Other
Intended target group(s) Vegetarian, Adult (18 - 50 Years), Kosher, Gluten Free, Dairy Free, Sugar Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Stevia by plnt, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
7 Drop(s)
Maximum serving Sizes:
7 Drop(s)
Servings per container
590
UPC/BARCODE
766536024933
IngredientAmount% DV
Stevia leaf extract50 mg--

Other ingredients: Vegetable Glycerin, deionized Water

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
General Statements

Pure living, naturally true

Formula

Naturally flavored

K Parve K-1604

Formulation

Non-GMO Zero Calories

Gluten free Dairy free Nut free Soy free

Does not contain: Gluten, Sugar, Salt, Animal Derivatives, Preservatives, Artificial Colors or Flavors.

Seals/Symbols

Non GMO Project Verified Nongmoproject.org

K Parve K-1604 Quality promise Tested & trusted

FDA Statement of Identity

Liquid Dietary Supplement

Storage

Store in a cool, dry place.

Precautions

Keep out of reach of children.

Tamper evident Do not use if outer seal is broken.

Warning: Consult your healthcare provider prior to use if pregnant, nursing, taking any medication or have any medical conditions.

Suggested/Recommended/Usage/Directions

Directions: Add up to 7 drops to beverages or food. Adjust as needed.

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Stevia by plnt label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Stevia label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Stevia by plnt

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size7 Drop(s) Dosage formLiquid Servings per container590 Amounts shown are per serving.

Stevia leaf extract

Interacts with
259 drugs
50 mg per serving

Stevia is a plant-based, calorie-free sweetener that is widely used as a sugar alternative and is considered safe in normal food amounts by major regu...

Stevia leaf extract monograph & interactions

Other (inactive) ingredients: Vegetable Glycerin, Deionized Water. These complete the product’s ingredient list but are not active constituents.

Interaction report

Stevia by plnt Drug Interactions

Want to check YOUR meds against Stevia?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
259Drugs
1 Moderate 258 Minor

Ingredients driving the most interactions

Stevia leaf extract 259

Individual Drug Interactions

The ingredients in Stevia interact with 259 drugs. Click any drug to see the details.

1 of the 1 ingredient in Stevia interact with drugs. Each result below shows which ingredient is responsible. Stevia leaf extract

Each ingredient & the kinds of drugs it affects

For each ingredient in Stevia with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Stevia leaf extract3 drug types · 259 drugs

Lithium

Theoretically, stevia might decrease clearance and increase levels of lithium.
Animal research suggests that stevia extracts might have diuretic activity. Theoretically, increased reabsorption of lithium along with sodium might reduce excretion and increase levels of lithium.

Likelihood Possible Evidence D
Antidiabetes Drugs

Theoretically, stevia might increase the risk for hypoglycemia when combined with antidiabetes drugs.
Preliminary clinical research in patients with type 2 diabetes suggests that taking a single dose of stevia extract 1000 mg reduces postprandial blood glucose levels when taken with a meal. However, other clinical research in patients with type 1 or type 2 diabetes suggests that taking stevioside 250 mg three times daily does not significantly affect blood glucose levels or glycated hemoglobin (HbA1C) after three months of treatment.

Likelihood Possible Evidence D
Antihypertensive Drugs

Theoretically, combining stevia or stevia constituents with antihypertensive agents might increase the risk of hypotension.
Stevia extract and stevioside might lower blood pressure in patients with hypertension. However, other clinical research suggests that stevioside does not significantly lower blood pressure in patients with hypertension.

Likelihood Possible Evidence D
Stevia leaf extract full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Stevia, from the product label.

plnt

See all plnt products
Name
Vitamin Shoppe, Inc.
City
Secaucus
State
NJ
ZipCode
07094
Phone Number
1-866-293-3367
Web Address
www.vitaminshoppe.com
Pharmacist Counseling Corner

Stevia by plnt: Common Questions

Does Stevia by plnt interact with any medications?
Yes. Based on its ingredients, Stevia has a known interaction with 259 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Stevia contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Is stevia safe to use every day?
Purified stevia sweeteners at normal food amounts are generally recognized as safe for daily use. But this is a supplement-strength liquid, not a food product, and high-dose supplements haven't been well studied long-term. If you use it regularly, it's worth discussing with your pharmacist.
Will stevia help me lose weight or control my blood sugar?
The evidence isn't strong enough yet to say. We have insufficient reliable evidence that stevia works for weight loss, blood sugar control, or high blood pressure. Some small studies hint at short-term effects on blood sugar, but others haven't confirmed it.
What are the most common side effects?
The most common ones are bloating, dizziness, headache, muscle pain, nausea, and numbness. Most of these are minor and usually go away after the first week of use. Serious allergic reactions are rare.
Can I use stevia if I'm pregnant or breastfeeding?
We don't have safety data on file for stevia during pregnancy or breastfeeding. Talk with your doctor or pharmacist about whether it's right for you in those situations — they can give you personalized advice based on your full health picture.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Stevia is safe with your meds?

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Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Stevia label
Go deeper

The Full Monographs Behind Stevia’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Stevia

Interacts with 259 drugs

Stevia is a plant-based, calorie-free sweetener that is widely used as a sugar alternative and is considered safe in normal food amounts by major regulators. Purified stevia extracts have a...

Read the full Stevia monograph →
Sources

Sources & How We Checked

Stevia's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 10 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Stevia 10 references
  1. Chan P, Xu DY, Liu JC, et al. The effect of stevioside on blood pressure and plasma catecholamines in spontaneously hypertensive rats. Life Sci 1998;63:1679-84. PubMed
  2. Melis MS. A crude extract of Stevia rebaudiana increases the renal plasma flow of normal and hypertensive rats. Braz J Med Biol Res 1996;29:669-75.
  3. Melis MS. Chronic administration of aqueous extract of Stevia rebaudiana in rats: renal effects. J Ethnopharmacol 1995;47:129-34. PubMed
  4. Melis MS, Sainati AR. Effect of calcium and verapamil on renal function of rats during treatment with stevioside. J Ethnopharmacol 1991;33:257-622. PubMed
  5. Hsieh MH, Chan P, Sue YM, et al. Efficacy and tolerability of oral stevioside in patients with mild essential hypertension: a two-year, randomized, placebo-controlled study. Clin Ther 2003;25:2797-808. PubMed
  6. Chan P, Tomlinson B, Chen YJ, et al. A double-blind placebo-controlled study of the effectiveness and tolerability of oral stevioside in human hypertension. Br J Clin Pharmacol 2000;50:215-20. PubMed
  7. Gregersen S, Jeppesen PB, Holst JJ, Hermansen K. Antihyperglycemic effects of stevioside in type 2 diabetic subjects. Metabolism 2004;53:73-6. PubMed
  8. Barriocanal LA, Palacios M, Benitez G, et al. Apparent lack of pharmacological effect of steviol glycosides used as sweeteners in humans. A pilot study of repeated exposures in some normotensive and hypotensive individuals and in Type 1 and Type 2 diabeti
  9. Ferri LA, Alves-Do-Prado W, Yamada SS, et al. Investigation of the antihypertensive effect of oral crude stevioside in patients with mild essential hypertension. Phytother Res 2006;20:732-6. PubMed
  10. Almiron-Roig E, Navas-Carretero S, Castelnuovo G, et al. Impact of acute consumption of beverages containing plant-based or alternative sweetener blends on postprandial appetite, food intake, metabolism, and gastro-intestinal symptoms: Results of the SWEE

See these in context on the Stevia monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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