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Dietary supplement

SulforaXym Ingredients & Drug Interactions

by Tomorrow's Nutrition Pro

Capsule Category: Other Combinations
Most serious interaction: Moderate
The interaction bottom line Most serious interaction: Moderate

SulforaXym is a dietary supplement by Tomorrow's Nutrition Pro with 1 active ingredient. Its ingredients are commonly taken for general nutrition and antioxidant support, heart and digestive health, detoxification support.Based on those ingredients, 723 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Broccoli, Powder. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

HelloPharmacist Scorecard of SulforaXym by Tomorrow's Nutrition Pro

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

What’s inside

Partial disclosure
Ingredient Transparency · database check
Partial

Most active ingredients list an amount, but at least one is hidden in a blend or missing.

Why this rating?
  • The label discloses an exact amount for 2 of its 3 active ingredients.
  • “Broccoli, Powder” is listed as a grouped ingredient — the label gives one combined amount (1,336 mg) without saying how much of each component you get.

SulforaXym has three active ingredients. Sulforaphane is the main one — it's a compound from cruciferous vegetables like broccoli that's been studied for several health effects.

Broccoli powder provides sulforaphane naturally. Myrosinase is an enzyme that may help your body activate sulforaphane from the broccoli, though we have no interaction data on file for it.

The product also contains AstraZyme, a digestive enzyme blend we couldn't check for interactions. The capsules are filled out with cellulose and water as inactive ingredients.

Does it work?

Moderate evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed

This product doesn't appear to be marketed for a specific use, so we graded Sulforaphane's overall clinical evidence instead.

Moderate

Some clinical evidence supports Sulforaphane for:

Why this rating?
  • We looked at the product name, claims, and label statements and couldn't find a stated purpose to grade.
  • Since the label doesn't commit to one use, we graded the ingredient's overall clinical evidence instead.
  • On file: Prostate cancer — rated "Possibly Effective" (Natural Medicines).

The evidence for sulforaphane varies by use. It's rated possibly effective for prostate cancer, meaning there's some supportive research but it's not yet proven.

For hay fever (allergic rhinitis) and asthma, we don't have enough reliable evidence to say whether it works. Cancer prevention in general also lacks established evidence in our data.

The rating for Helicobacter pylori (a stomach bacteria) is possibly ineffective, so it's unlikely to help with that infection.

The evidence, ingredient by ingredient Broccoli Sulforaphane

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Sulforaphane from food is considered safe, but concentrated supplements like this one haven't been studied as thoroughly for long-term use — that's worth keeping in mind. The most common side effects from oral sulforaphane are bowel discomfort, heartburn, stomach upset, and vomiting.

Less common ones include headache, insomnia, and irritability. There are also reports of seizures in males with autism taking sulforaphane, though these are rare.

One study noted that males aged 13–27 with autism gained an average of 4 pounds more over 18 weeks on sulforaphane than on placebo. For pregnancy, the safety data advises against concentrated supplements — stick to normal food amounts instead.

While breastfeeding, there isn't enough information on supplement-level doses, so use caution and prefer getting sulforaphane from your diet.

Side effects, ingredient by ingredient Broccoli Sulforaphane

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Sulforaphane.
  • The most serious interaction on file is rated Moderate.
  • For scale: 723 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before taking this product, check your medications against CYP3A4 substrates, CYP1A2 substrates, and CYP2E1 substrates — all carry Moderate severity interactions with sulforaphane. CYP3A4 drugs (the most affected group) may have increased levels and effects.

If you're unsure whether your medications fall into these categories, your pharmacist can look them up with you using the tool on this page.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glancePartially disclosed formula with some supporting evidence behind its ingredients' uses. Moderate medication interactions have been identified, and safety information is well characterized.

SulforaXym is worth considering if you're interested in sulforaphane for prostate health and you don't take medications that interact with liver enzymes. If you take any prescriptions at all, check them against the interaction list on this page first — the medication count is large.

Talk to your pharmacist before starting, especially if you're pregnant, breastfeeding, or have a history of seizures.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 3 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Jul 24, 2025.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about SulforaXym, straight from the product label.

Brand Tomorrow's Nutrition Pro
Barcode (UPC) 850236004354
Net contents 62 Vegetable Capsule(s)
Market status On market
Date entered into DSLD Jul 24, 2025
DSLD ID 336301
Product type Other Combinations
Supplement form Capsule
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Vegan, Vegetarian, Adult (18 - 50 Years), Kosher, Gluten Free, Dairy Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for SulforaXym by Tomorrow's Nutrition Pro, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
2 Capsule(s)
Maximum serving Sizes:
2 Capsule(s)
Servings per container
31
UPC/BARCODE
850236004354
IngredientAmount% DV
Calories5 Calorie(s)--
Total Carbohydrates1 Gram(s)1%
Broccoli, Powder1336 mg--
Sulforaphane5.34 mg--
Myrosinase0 NP--
AstraZyme20 mg--

Other ingredients: Cellulose, Water

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
General Statements

"You Can't Drug Yourself Healhthy" Dr. Eric Balcavage

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

Precautions

Warning: If pregnant, nursing, or taking prescription drugs, consult your healthcare practitioner prior to use.

Seals/Symbols

OK (Kosher)

Formula

OK (Kosher)

Broccoli sprouts + AstraZyme Contains standardized Sulforaphane Contains stabilized Myrosinase enzyme activity Contains AstraZyme

Formulation

Gluten free | Non-Dairy | Non-GMO | Vegan

Gluten free | Non-Dairy | Non-GMO | Vegan

Brand IP Statement(s)

AstraZyme is a registered trademark of ERCC, Inc.

FDA Statement of Identity

Dietary Supplement

Suggested/Recommended/Usage/Directions

Recommendations: Adults, as a dietary supplement, take two capsules daily.

See for yourself

SulforaXym by Tomorrow's Nutrition Pro label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

What’s inside

The Ingredients in SulforaXym by Tomorrow's Nutrition Pro

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size2 Capsule(s) Dosage formCapsule Servings per container31 Amounts shown are per serving.

Broccoli, Powder

Interacts with
187 drugs
1336 mg per serving

Broccoli is a nutritious cruciferous vegetable rich in fiber, vitamins, and plant compounds like sulforaphane that have drawn scientific interest for...

Broccoli, Powder monograph & interactions

Other (inactive) ingredients: Cellulose, Water. These complete the product’s ingredient list but are not active constituents.

Interaction report

SulforaXym by Tomorrow's Nutrition Pro Drug Interactions

Want to check YOUR meds against SulforaXym?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

Go to the checker
723Drugs
723 Moderate

Ingredients driving the most interactions

Each ingredient & the kinds of drugs it affects

For each ingredient in SulforaXym with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Broccoli, Powder2 drug types · 187 drugs

Cytochrome P450 1A2 (Cyp1A2) Substrates

Theoretically, broccoli might reduce the levels and effects of drugs metabolized by CYP1A2.
Pharmacokinetic research in humans shows that eating 500 grams of fresh broccoli daily for 6-12 days can increase CYP1A2 activity by 10% to 200%. Induction of CYP1A2 activity by broccoli is attributed to its glucosinolate constituents.

Likelihood Possible Evidence B
Cytochrome P450 2A6 (Cyp2A6) Substrates

Theoretically, broccoli might reduce the levels and effects of drugs metabolized by CYP2A6.
Pharmacokinetic research in humans shows that eating 500 grams of broccoli daily for 6 days increases CYP2A6 activity by 135% to 550%. Induction of CYP2A6 activity is attributed to its glucosinolate constituents.

Likelihood Possible Evidence B
The maker

Brand information

Manufacturer and brand details for SulforaXym, from the product label.

Tomorrow's Nutrition Pro

See all Tomorrow's Nutrition Pro products
Name
Tomorrow's Nutrition Pro
City
Minneapolis
State
MN
Phone Number
888.380.2322
Pharmacist Counseling Corner

SulforaXym by Tomorrow's Nutrition Pro: Common Questions

Does SulforaXym by Tomorrow's Nutrition Pro interact with any medications?
Yes. Based on its ingredients, SulforaXym has a known interaction with 723 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
SulforaXym contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Can I take SulforaXym if I'm pregnant or breastfeeding?
During pregnancy, the safety data advises against concentrated sulforaphane supplements — stick to sulforaphane from food instead. While breastfeeding, there isn't enough information on supplement-level doses, so use caution and prefer dietary sources. Talk to your doctor or pharmacist for personalized advice.
What side effects might I experience?
Most commonly, you might notice bowel discomfort, heartburn, stomach upset, or vomiting. Less common side effects include headache, insomnia, and irritability. There are also rare reports of seizures, particularly in males with autism. One study found participants gained an average of 4 pounds more over 18 weeks compared to placebo.
Does sulforaphane really work for cancer prevention?
The evidence isn't established yet. Sulforaphane is rated possibly effective for prostate cancer specifically, meaning there's some research support, but it's not proven. For cancer in general, we don't have enough reliable evidence in our data to say whether it works.
Will this help with hay fever or asthma?
We don't have enough reliable evidence to say whether sulforaphane works for hay fever or asthma. The data we hold isn't conclusive on either condition.
Why does the product contain broccoli powder if sulforaphane is the active ingredient?
Broccoli powder is a natural source of sulforaphane. The product also includes myrosinase, an enzyme that may help your body activate the sulforaphane from the broccoli.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if SulforaXym is safe with your meds?

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

SulforaXym label
Sources

Sources & How We Checked

SulforaXym's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 21 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Broccoli 5 references
  1. Kristal AR, Lampe JW. Brassica vegetables and prostate cancer risk: a review of the epidemiological evidence. Nutr Cancer 2002;42:1-9. PubMed
  2. Chakrabarti A, Prais L, Foulds IS. Allergic contact dermatitis to broccoli. Br J Dermatol 2003;148:172-3. PubMed
  3. Hakooz, N. and Hamdan, I. Effects of dietary broccoli on human in vivo caffeine metabolism: a pilot study on a group of Jordanian volunteers. Curr Drug Metab 2007;8(1):9-15. PubMed
  4. Kall MA, Vang O, Clausen J. Effects of dietary broccoli on human drug metabolising activity. Cancer Lett. 1997;114(1-2):169-70. PubMed
  5. Bauman JE, Hsu CH, Centuori S, et al. Randomized Crossover Trial Evaluating Detoxification of Tobacco Carcinogens by Broccoli Seed and Sprout Extract in Current Smokers. Cancers (Basel). 2022;14(9):2129. Published 2022 Apr 24. PubMed

See these in context on the Broccoli monograph →

Sulforaphane 16 references
  1. Park EJ, Pezzuto JM. Botanicals in cancer chemoprevention. Cancer Metastasis Rev 2002;21:231-55. PubMed
  2. Barcelo S, Mace K, Pfeifer AM, Chipman JK. Production of DNA strand breaks by N-nitrosodimethylamine and 2-amino-3-methylimidazo[4,5-f]quinoline in THLE cells expressing human CYP isoenzymes and inhibition by sulforaphane. Mutat Res 1998;402:111-20. PubMed
  3. Cipolla BG, Mandron E, Lefort JM, et al. Effect of sulforaphane in men with biochemical recurrence after radical prostatectomy. Cancer Prev Res (Phila). 2015;8(8):712-9. PubMed
  4. Fahey JW, Wade KL, Wehage SL, et al. Stabilized sulforaphane for clinical use: Phytochemical delivery efficiency. Mol Nutr Food Res. 2017 Apr;61(4). PubMed
  5. Alumkal JJ, Slottke R, Schwartzman J, et al. A phase II study of sulforaphane-rich broccoli sprout extracts in men with recurrent prostate cancer. Invest New Drugs. 2015;33(2):480-9. PubMed
  6. Heber D, Li Z, Garcia-Lloret M, et al. Sulforaphane-rich broccoli sprout extract attenuates nasal allergic response to diesel exhaust particles. Food Funct. 2014;5(1):35-41. PubMed
  7. Singh K, Connors SL, Macklin EA, et al. Sulforaphane treatment of autism spectrum disorder (ASD). Proc Natl Acad Sci U S A. 2014;111(43):15550-5. PubMed
  8. Wise RA, Holbrook JT, Criner G, et al. Lack of effect of oral sulforaphane administration on Nrf2 expression in COPD: A randomized, double-blind, placebo controlled trial. PLoS One. 2016;11(11):e0163716. PubMed
  9. Bent S, Lawton B, Warren T, et al. Identification of urinary metabolites that correlate with clinical improvements in children with autism treated with sulforaphane from broccoli. Mol Autism. 2018;9:35. PubMed
  10. Momtazmanesh S, Amirimoghaddam-Yazdi Z, Moghaddam HS, Mohammadi MR, Akhondzadeh S. Sulforaphane as an adjunctive treatment for irritability in children with autism spectrum disorder: A randomized, double-blind, placebo-controlled clinical trial. Psychiatr PubMed
  11. Fimognari C, Lenzi M, Hrelia P. Interaction of the isothiocyanate sulforaphane with drug disposition and metabolism: pharmacological and toxicological implications. Curr Drug Metab. 2008;9(7):668-78. PubMed
  12. Chinnappan SM, George A, Evans M, Anthony J. Efficacy of Labisia pumila and Eurycoma longifolia standardised extracts on hot flushes, quality of life, hormone and lipid profile of peri-menopausal and menopausal women: a randomised, placebo-controlled stud
  13. Mahéo K, Morel F, Langouët S, et al. Inhibition of cytochromes P-450 and induction of glutathione S-transferases by sulforaphane in primary human and rat hepatocytes. Cancer Res. 1997;57(17):3649-52.
  14. Yoxall V, Kentish P, Coldham N, Kuhnert N, Sauer MJ, Ioannides C. Modulation of hepatic cytochromes P450 and phase II enzymes by dietary doses of sulforaphane in rats: Implications for its chemopreventive activity. Int J Cancer. 2005;117(3):356-62. PubMed
  15. Zimmerman AW, Singh K, Connors SL, et al. Randomized controlled trial of sulforaphane and metabolite discovery in children with Autism Spectrum Disorder. Mol Autism 2021;12(1):38.
  16. Yusin J, Wang V, Henning SM, et al. The effect of broccoli sprout extract on seasonal grass pollen-induced allergic rhinitis. Nutrients 2021;13(4):1337. PubMed

See these in context on the Sulforaphane monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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