Interactions on record — worth a quick check against your medications. Check your meds →
Dietary supplement

Super Joints 1500 mg Ingredients & Drug Interactions

by 8WeeksOut

Super Joints 1500 mg label
See full label image
Capsule Category: Botanical
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 16, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Super Joints 1500 mg against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Super Joints 1500 mg is a dietary supplement by 8WeeksOut with 1 active ingredient. Its ingredients are commonly taken for bone fracture healing, joint pain and bone health, weight management.Based on those ingredients, 86 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Cissus quadrangularis (stem) extract. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

Jump to a section

Check Your Meds Against Super Joints 1500 mg by 8WeeksOut

Ask about any prescription or over-the-counter medication and we check it for interactions with Super Joints 1500 mg by 8WeeksOut — and tell you which ingredient is responsible.

Pharmacist-reviewed data Checks every ingredient Answer in seconds
Prefer a human? Send your question to our licensed pharmacists — free, answered by email within 24 hours.

HelloPharmacist Scorecard of Super Joints 1500 mg by 8WeeksOut

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Jul 11, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

Super Joints 1500 mg is a single-ingredient product: Cissus quadrangularis stem extract at 1,500 mg per capsule. Cissus quadrangularis is a woody vine used in traditional medicine, and in clinical research it has been studied mainly for its effects on body weight and metabolic markers.

The capsule itself is gelatin, and the product also contains rice flour and magnesium stearate as inactive ingredients.

Does it work?

Not established
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not established

The graded evidence we hold for these ingredients covers different conditions than the ones this product is marketed for, so there's no established rating for its stated use — see Cissus Quadrangularis's own graded uses on its monograph.

Why this rating?
  • The label markets this product for: Joint pain relief and bone fracture healing.
  • We looked for evidence on: Joint pain, Fractures, Osteoporosis, Osteopenia, Rheumatoid arthritis (RA), Gout — and 3 related terms.
  • The closest evidence on file: Cissus Quadrangularis is rated "Insufficient Reliable Evidence To Rate" for Osteopenia (Natural Medicines).
  • Also on file: Cissus Quadrangularis is rated "Insufficient Reliable Evidence To Rate" for Fractures, Osteoporosis, Joint pain, Rheumatoid arthritis (RA), and more.

The evidence for Cissus quadrangularis is mixed and depends on what you're taking it for. For obesity, the data rates it as possibly effective — small studies suggest it may help with weight management, particularly in people who are already overweight or obese.

For high cholesterol (hyperlipidemia), weak bones (osteopenia), cancer, and epilepsy, there isn't enough reliable evidence in our data to rate whether it works. The product is marketed for joint support, but we don't hold effectiveness data for that specific claim.

The evidence, ingredient by ingredient Cissus Quadrangularis

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Cissus quadrangularis is generally well tolerated in short-term use, though long-term safety hasn't been well studied, so we don't know what happens if you take it for years. Some people in trials reported headache and insomnia, but these happened at rates similar to or lower than placebo.

Others reported flatulence, diarrhea, stomach irritation (gastritis), and dry mouth — again, at rates no worse than placebo. The safety data advises against use during pregnancy and while breastfeeding because there isn't enough information to know it's safe in those situations.

Side effects, ingredient by ingredient Cissus Quadrangularis

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Cissus Quadrangularis.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: diabetes medications.
  • For scale: 86 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

If you take any medication to lower blood sugar (antidiabetes drugs), double-check it with the tool on this page before starting Super Joints 1500 mg. The combination carries a Moderate risk of low blood sugar.

No other major medication interactions are documented for the ingredient we could check.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with no established evidence rating for its marketed use. Moderate medication interactions have been identified, and safety information is well characterized.

If you're looking at Super Joints for weight management and don't take diabetes medication, you're starting from a position where documented interactions are unlikely. If you do take a blood-sugar-lowering drug, check with your pharmacist first.

Pregnant or nursing — this one isn't the right choice given the limited safety data. Long-term safety data is thin, so a conversation with your pharmacist about your individual situation will help.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Jun 24, 2020.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Super Joints 1500 mg, straight from the product label.

Brand 8WeeksOut
Barcode (UPC) 647732625622
Net contents 180 Capsule(s)
Market status On market
Date entered into DSLD Jun 24, 2020
DSLD ID 228472
Product type Botanical
Supplement form Capsule
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years), Women (not pregnant or lactating)
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Super Joints 1500 mg by 8WeeksOut, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
2 Capsule(s)
Maximum serving Sizes:
2 Capsule(s)
Servings per container
90
UPC/BARCODE
647732625622
IngredientAmount% DV
Cissus quadrangularis (stem) extract1500 mg--

Other ingredients: Gelatin Caps, Rice Flour, Magnesium Stearate

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Formula

SuperJoints: Contains the famous award winning cissus quadragularis extract which has been the subject of several university pilot studies known for its miraculous ability to turn around stubborn joint problems.

Super Joints 1500 mg per dose

100% cissus quadrangularis

Formulation

Clinical studies have shown promise of: Analgestic joint pain relief Muscle relaxing anti-inflamatory properties Increase bone fracture healing rates Antioxidant properties Promotes improved body composition

Professional joint relief

Best of the best joint support

Suggested/Recommended/Usage/Directions

Directions: Take two capsules 30 minutes before breakfast, and two capsule 30 minutes before dinner. Once relief is achieved, take a single maintenance dose daily.

Precautions

Warnings: Keep out of reach of children.

Do not use if pregnant or breastfeeding.

Cissus quadrangularis might lower blood sugar.

Taking cissus quadrangularis along with medications for diabetes might lower blood sugar too much.

Watch for signs of low blood sugar (hypoglycemia) and monitor your blood sugar levels closely if you have diabetes and use cissus quadrangularis.

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

General Statements

100% money back guarantee

Award winning studies

FDA Statement of Identity

Dietary Supplement

Seals/Symbols

ASI Food Safety FDA Registered Facility GMP Good Manufacturing Practice Consistent Quality Made in U.S.A.

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Super Joints 1500 mg by 8WeeksOut label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Super Joints 1500 mg label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Super Joints 1500 mg by 8WeeksOut

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size2 Capsule(s) Dosage formCapsule Servings per container90 Amounts shown are per serving.

Cissus quadrangularis (stem) extract

Interacts with
86 drugs
1500 mg per serving

Cissus quadrangularis is a traditional vine used mainly for bone health, joint pain, and weight management. Most of the supporting evidence comes from...

Cissus quadrangularis (stem) extract monograph & interactions

Other (inactive) ingredients: Gelatin Caps, Rice Flour, Magnesium Stearate. These complete the product’s ingredient list but are not active constituents.

Interaction report

Super Joints 1500 mg by 8WeeksOut Drug Interactions

Want to check YOUR meds against Super Joints 1500 mg?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
86Drugs
86 Moderate

Ingredients driving the most interactions

Cissus quadrangularis (stem) extract 86

Individual Drug Interactions

The ingredients in Super Joints 1500 mg interact with 86 drugs. Click any drug to see the details.

1 of the 1 ingredient in Super Joints 1500 mg interact with drugs. Each result below shows which ingredient is responsible. Cissus quadrangularis (stem) extract

Each ingredient & the kinds of drugs it affects

For each ingredient in Super Joints 1500 mg with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Cissus quadrangularis (stem) extract1 drug type · 86 drugs

Antidiabetes Drugs

Theoretically, Cissus quadrangularis might increase the risk of hypoglycemia when taken with antidiabetes drugs.
Small clinical studies suggest that Cissus quadrangularis might reduce fasting blood glucose in individuals with overweight or obesity.

Likelihood Possible Evidence D
Cissus quadrangularis (stem) extract full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Super Joints 1500 mg, from the product label.

8WeeksOut

See all 8WeeksOut products
Name
8WeeksOut
City
San Antonio
State
TX
ZipCode
78259
Web Address
www.8weeksoutlabs.com
Pharmacist Counseling Corner

Super Joints 1500 mg by 8WeeksOut: Common Questions

Does Super Joints 1500 mg by 8WeeksOut interact with any medications?
Yes. Based on its ingredients, Super Joints 1500 mg has a known interaction with 86 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Super Joints 1500 mg contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Can I take this if I have diabetes?
If you take a diabetes medication, you'll need to check your specific drug with our interaction tool first. Cissus quadrangularis might increase the risk of low blood sugar when combined with antidiabetes drugs. Your pharmacist or doctor can tell you whether it's safe for you personally.
Is it safe to take while pregnant?
No, the safety data advises against it. There isn't enough information to know whether Cissus quadrangularis is safe during pregnancy, so it's best avoided. Talk with your doctor before taking any new supplement if you're pregnant or planning to be.
What are the side effects?
The most common reports were headache, insomnia, flatulence, diarrhea, stomach irritation, and dry mouth. However, in clinical trials these happened at rates similar to or lower than placebo, so they're not major concerns. Most people tolerate it well in short-term use.
Does it actually help with joints?
The product is marketed for joint support, but we don't hold effectiveness data for that specific claim. The research we do have focuses on weight management and metabolic effects, where it's rated as possibly effective for obesity.
How long can I safely take this?
Short-term safety is established, but long-term safety hasn't been well studied. If you're thinking about taking it for months or longer, it's worth checking in with your pharmacist about whether that's right for you.
Can I take it while breastfeeding?
No, the safety data advises against it. There isn't enough information to know whether it's safe while breastfeeding, so it's best avoided. Talk with your doctor or pharmacist if you have questions.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Super Joints 1500 mg is safe with your meds?

Our pharmacists answer your medication & supplement questions — free.

Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Super Joints 1500 mg label
Go deeper

The Full Monographs Behind Super Joints 1500 mg’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Cissus Quadrangularis

Interacts with 86 drugs

Cissus quadrangularis is a traditional vine used mainly for bone health, joint pain, and weight management. Most of the supporting evidence comes from animal studies and a small number of hu...

Read the full Cissus Quadrangularis monograph →
Sources

Sources & How We Checked

Super Joints 1500 mg's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 5 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Cissus Quadrangularis 5 references
  1. Oben J, Kuate D, Agbor G, et al. The use of a Cissus quadrangularis formulation in the management of weight loss and metabolic syndrome. Lipids Health Dis 2006, 5:24.
  2. Oben JE, Ngondi JL, Momo CN, et al. The use of Cissus quadrangularis/Irvingia gabonensis combination in the management of weight loss: a double-blind placebo-controlled study. Lipids Health Dis 2008;7:12.
  3. Panpimanmas, S., Sithipongsri, S., Sukdanon, C., and Manmee, C. Experimental comparative study of the efficacy and side effects of Cissus quadrangularis L. (Vitaceae) to Daflon (Servier) and placebo in the treatment of acute hemorrhoids. J Med Assoc.Thai
  4. Nash R, Azantsa B, Kuate D, Singh H, Oben J. The use of a stem and leaf aqueous extract of Cissus quadrangularis (CQR-300) to reduce body fat and other components of metabolic syndrome in overweight participants. J Altern Complement Med. 2019;25(1):98-106
  5. Benjawan S, Nimitphong H, Tragulpiankit P, Musigavong O, Prathanturarug S, Pathomwichaiwat T. The effect of Cissus quadrangularis L. on delaying bone loss in postmenopausal women with osteopenia: A randomized placebo-controlled trial. Phytomedicine 2022;1 PubMed

See these in context on the Cissus Quadrangularis monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

Keep exploring
Supplement interaction checker › Check any supplement or product against your medications Drug–drug interactions › Check two or more of your medications against each other Browse medications A–Z › Every drug we've checked against herbs & supplements NDC & pricing lookup › Find a drug’s NDCs, packaging and costs Ask a pharmacist › Free, personal answer from our licensed team