Super Strength Oregano 500 mg Ingredients & Drug Interactions
What is this page for?
First and foremost: checking Super Strength Oregano 500 mg against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.
Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy
Super Strength Oregano 500 mg is a dietary supplement by Swanson Superior Herbs with 2 active ingredients. Its ingredients are commonly taken for digestive upset, respiratory and cold symptoms, antimicrobial support.Based on those ingredients, 1,346 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Sage (Salvia officinalis) extract, Oregano (Origanum vulgare) extract. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.
Check Your Meds Against Super Strength Oregano 500 mg by Swanson Superior Herbs
Ask about any prescription or over-the-counter medication and we check it for interactions with Super Strength Oregano 500 mg by Swanson Superior Herbs — and tell you which ingredient is responsible.
AI summaries are generated from our interaction database for education only — always confirm with your pharmacist. How we use AI
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HelloPharmacist Scorecard of Super Strength Oregano 500 mg by Swanson Superior Herbs
Four independent checks of what is known — a summary of the available information, not a grade of the product itself.
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
The stated purpose hasn't been mapped to our evidence data yet.
Why this rating?
- We haven't mapped this product's purpose to our evidence data yet — it'll be graded on the next content refresh.
Most active ingredients don't disclose an individual amount — you can't tell how much of each you're getting.
Why this rating?
- The label discloses an exact amount for 0 of its 2 active ingredients.
- “Origanox” is listed as a grouped ingredient — the label gives one combined amount (500 mg) without saying how much of each component you get.
The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.
Why this rating?
- 2 of the 2 matched ingredients can interact with medications — Sage, Oregano.
- The most serious interaction on file is rated Moderate.
- Some involve high-stakes drug classes: anticoagulant / antiplatelet drugs; seizure medications; diabetes medications.
- For scale: 1,347 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.
Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.
Why this rating?
- We hold adverse-effect (side-effect) data for 2 of the 2 matched ingredients.
- Pregnancy & breastfeeding safety ratings cover 2 of 2.
- General safety write-ups exist for 2 of 2.
- Remember: this measures how much safety information exists. Thin data is not the same as being safe.
HelloPharmacist summaryFormula with limited ingredient disclosure with no assessable stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.
Assessment coverage: 2 of 2 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Aug 31, 2018.
This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed
General information
Key facts about Super Strength Oregano 500 mg, straight from the product label.
| Brand | Swanson Superior Herbs |
|---|---|
| Barcode (UPC) | 087614142166 |
| Net contents | 60 Capsule(s) |
| Market status | Off market |
| Date entered into DSLD | Aug 31, 2018 |
| DSLD ID | 180576 |
| Product type | Botanical |
| Supplement form | Capsule |
| Dietary claims / uses | All Other |
| Intended target group(s) | Adult (18 - 50 Years) |
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.
Supplement Facts
The label details for Super Strength Oregano 500 mg by Swanson Superior Herbs, sourced from the NIH Dietary Supplement Label Database.
Supplement Facts
| Ingredient | Amount | % DV |
|---|---|---|
| Origanox | 500 mg | -- |
| Oregano (Origanum vulgare) extract | 0 NP | -- |
| Sage (Salvia officinalis) extract | 0 NP | -- |
Other ingredients: Gelatin, Rice Flour, Calcium Palmitate
Tap any ingredient to jump to its full detail below.
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Formula
Origanox powerful natural antioxidant
FDA Statement of Identity
Standardized Herbal Supplement
Seals/Symbols
Guaranteed purity & potency
Precautions
Do not use if seal is broken.
Keep out of reach of children.
If using medication, consult your physician prior to use.
Storage
Store in a cool, dry place.
Suggested/Recommended/Usage/Directions
Suggested use: As a dietary supplement, take one capsule two times daily at regular intervals preferably with meals or as directed by a qualified healthcare professional. If using medication, consult your physician prior to use.
General Statements
To reorder, call toll free 1-800-437-4148 or visit our website at www.swansonvitamins.com
Brand IP Statement(s)
Origanox is a trademark of Barrington Nutritionals.
General
SWH216 Rev 1 01 18 18
Is this label outdated? Report a formula or label change and our pharmacy team will review it.
Super Strength Oregano 500 mg by Swanson Superior Herbs label
The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.
Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.
View the full label (PDF)The Ingredients in Super Strength Oregano 500 mg by Swanson Superior Herbs
These are the 2 active ingredients this product is made of. Select any to open its full monograph.
Serving size1 Capsule(s) Dosage formCapsule Amounts shown are per serving.
Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.
Other (inactive) ingredients: Gelatin, Rice Flour, Calcium Palmitate. These complete the product’s ingredient list but are not active constituents.
Super Strength Oregano 500 mg by Swanson Superior Herbs Drug Interactions
Super Strength Oregano 500 mg contains 2 ingredients, and 2 of them have known drug interactions. Altogether they interact with 1,346 medications. Here’s the picture, then you can look up your own drug.
Want to check YOUR meds against Super Strength Oregano 500 mg?
Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.
Go to the checkerIngredients driving the most interactions
Individual Drug Interactions
The ingredients in Super Strength Oregano 500 mg interact with 1,346 drugs. Click any drug to see the details.
2 of the 2 ingredients in Super Strength Oregano 500 mg interact with drugs. Each result below shows which ingredient is responsible. Sage (Salvia officinalis) extract Oregano (Origanum vulgare) extract
Ado-trastuzumab EmtansineKadcyla
How Ado-trastuzumab Emtansine interacts with Super Strength Oregano 500 mg — through 1 ingredient. Tap an ingredient for the detail:
Sage (salvia Officinalis) ExtractCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, sage might increase the levels and clinical effects of drugs metabolized by CYP3A4.
Read the full Sage (salvia Officinalis) Extract + Ado-trastuzumab Emtansine interactionAbciximabReoPro
How Abciximab interacts with Super Strength Oregano 500 mg — through 1 ingredient. Tap an ingredient for the detail:
Oregano (origanum Vulgare) ExtractAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, oregano might increase the risk of bleeding when taken with anticoagulant or antiplatelet drugs.
Read the full Oregano (origanum Vulgare) Extract + Abciximab interactionAbemaciclibVerzenio
How Abemaciclib interacts with Super Strength Oregano 500 mg — through 1 ingredient. Tap an ingredient for the detail:
Sage (salvia Officinalis) ExtractCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, sage might increase the levels and clinical effects of drugs metabolized by CYP3A4.
Read the full Sage (salvia Officinalis) Extract + Abemaciclib interactionAbiraterone
How Abiraterone interacts with Super Strength Oregano 500 mg — through 1 ingredient. Tap an ingredient for the detail:
Sage (salvia Officinalis) ExtractCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, sage might increase the levels and clinical effects of drugs metabolized by CYP3A4.
Read the full Sage (salvia Officinalis) Extract + Abiraterone interactionAbiraterone AcetateYonsa, Zytiga
How Abiraterone Acetate interacts with Super Strength Oregano 500 mg — through 1 ingredient. Tap an ingredient for the detail:
Sage (salvia Officinalis) ExtractCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, sage might increase the levels and clinical effects of drugs metabolized by CYP3A4.
Read the full Sage (salvia Officinalis) Extract + Abiraterone Acetate interactionAbrocitinibCibinqo
How Abrocitinib interacts with Super Strength Oregano 500 mg — through 2 ingredients. Tap an ingredient for the detail:
Sage (salvia Officinalis) ExtractCytochrome P450 2c19 (cyp2c19) Substrates, Cytochrome P450 2c9 (cyp2c9) Substrates Moderate
Interaction Summary
Theoretically, sage might increase the levels and clinical effects of drugs metabolized by CYP2C19.
Read the full Sage (salvia Officinalis) Extract + Abrocitinib interactionOregano (origanum Vulgare) ExtractAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, oregano might increase the risk of bleeding when taken with anticoagulant or antiplatelet drugs.
Read the full Oregano (origanum Vulgare) Extract + Abrocitinib interactionAcalabrutinibCalquence
How Acalabrutinib interacts with Super Strength Oregano 500 mg — through 1 ingredient. Tap an ingredient for the detail:
Sage (salvia Officinalis) ExtractCytochrome P450 3a4 (cyp3a4) Substrates, P-glycoprotein Substrates Moderate
Interaction Summary
Theoretically, sage might increase the levels and clinical effects of drugs metabolized by CYP3A4.
Read the full Sage (salvia Officinalis) Extract + Acalabrutinib interactionAcarboseGlucobay, Prandase, Precose
How Acarbose interacts with Super Strength Oregano 500 mg — through 2 ingredients. Tap an ingredient for the detail:
Sage (salvia Officinalis) ExtractAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, taking sage with antidiabetes drugs might increase the risk of hypoglycemia.
Read the full Sage (salvia Officinalis) Extract + Acarbose interactionOregano (origanum Vulgare) ExtractAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, oregano might increase the risk for hypoglycemia when taken with antidiabetes drugs.
Read the full Oregano (origanum Vulgare) Extract + Acarbose interactionAcebutololRhotral, Sectral
How Acebutolol interacts with Super Strength Oregano 500 mg — through 1 ingredient. Tap an ingredient for the detail:
Sage (salvia Officinalis) ExtractAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, sage might increase or decrease the effects of antihypertensive drugs.
Read the full Sage (salvia Officinalis) Extract + Acebutolol interactionAcenocoumarolSintrom
How Acenocoumarol interacts with Super Strength Oregano 500 mg — through 1 ingredient. Tap an ingredient for the detail:
Oregano (origanum Vulgare) ExtractAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, oregano might increase the risk of bleeding when taken with anticoagulant or antiplatelet drugs.
Read the full Oregano (origanum Vulgare) Extract + Acenocoumarol interactionAcepromazineAtravet
How Acepromazine interacts with Super Strength Oregano 500 mg — through 1 ingredient. Tap an ingredient for the detail:
Sage (salvia Officinalis) ExtractCns Depressants, Anticholinergic Drugs Moderate
Interaction Summary
Theoretically, taking sage might increase the sedative and adverse effects of CNS depressants.
Read the full Sage (salvia Officinalis) Extract + Acepromazine interactionAcetaminophenChildren's Tylenol, Children's Tylenol Meltaways, Tylenol, Tylenol Ex Strength
How Acetaminophen interacts with Super Strength Oregano 500 mg — through 1 ingredient. Tap an ingredient for the detail:
Sage (salvia Officinalis) ExtractCytochrome P450 2e1 (cyp2e1) Substrates Moderate
Interaction Summary
Theoretically, sage might decrease the levels and clinical effects of drugs metabolized by CYP2E1.
Read the full Sage (salvia Officinalis) Extract + Acetaminophen interactionAcetaminophen, AspirinGemnisyn
How Acetaminophen, Aspirin interacts with Super Strength Oregano 500 mg — through 2 ingredients. Tap an ingredient for the detail:
Sage (salvia Officinalis) ExtractCytochrome P450 2e1 (cyp2e1) Substrates Moderate
Interaction Summary
Theoretically, sage might decrease the levels and clinical effects of drugs metabolized by CYP2E1.
Read the full Sage (salvia Officinalis) Extract + Acetaminophen, Aspirin interactionOregano (origanum Vulgare) ExtractAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, oregano might increase the risk of bleeding when taken with anticoagulant or antiplatelet drugs.
Read the full Oregano (origanum Vulgare) Extract + Acetaminophen, Aspirin interactionAcetaminophen, Aspirin, CaffeineExcedrin, Excedrin Extra Strength, Excedrin Migraine
How Acetaminophen, Aspirin, Caffeine interacts with Super Strength Oregano 500 mg — through 2 ingredients. Tap an ingredient for the detail:
Oregano (origanum Vulgare) ExtractAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, oregano might increase the risk of bleeding when taken with anticoagulant or antiplatelet drugs.
Read the full Oregano (origanum Vulgare) Extract + Acetaminophen, Aspirin, Caffeine interactionSage (salvia Officinalis) ExtractCytochrome P450 2e1 (cyp2e1) Substrates, Cytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, sage might decrease the levels and clinical effects of drugs metabolized by CYP2E1.
Read the full Sage (salvia Officinalis) Extract + Acetaminophen, Aspirin, Caffeine interactionAcetaminophen, Brompheniramine, PhenylpropanolamineDimetapp Cold and Flu
How Acetaminophen, Brompheniramine, Phenylpropanolamine interacts with Super Strength Oregano 500 mg — through 1 ingredient. Tap an ingredient for the detail:
Sage (salvia Officinalis) ExtractCytochrome P450 2e1 (cyp2e1) Substrates Moderate
Interaction Summary
Theoretically, sage might decrease the levels and clinical effects of drugs metabolized by CYP2E1.
Read the full Sage (salvia Officinalis) Extract + Acetaminophen, Brompheniramine, Phenylpropanolamine interactionAcetaminophen, ButalbitalAxocet, Bancap, Bucet, Butex Forte, Esgic CF, Orbivan CF +5 more
How Acetaminophen, Butalbital interacts with Super Strength Oregano 500 mg — through 1 ingredient. Tap an ingredient for the detail:
Sage (salvia Officinalis) ExtractCytochrome P450 2e1 (cyp2e1) Substrates Moderate
Interaction Summary
Theoretically, sage might decrease the levels and clinical effects of drugs metabolized by CYP2E1.
Read the full Sage (salvia Officinalis) Extract + Acetaminophen, Butalbital interactionAcetaminophen, Butalbital, CaffeineEsgic, Esgic Plus, Fiogesic, Fioricet, Repan, Tecnal +1 more
How Acetaminophen, Butalbital, Caffeine interacts with Super Strength Oregano 500 mg — through 1 ingredient. Tap an ingredient for the detail:
Sage (salvia Officinalis) ExtractCytochrome P450 2e1 (cyp2e1) Substrates, Cytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, sage might decrease the levels and clinical effects of drugs metabolized by CYP2E1.
Read the full Sage (salvia Officinalis) Extract + Acetaminophen, Butalbital, Caffeine interactionAcetaminophen, Butalbital, Caffeine, CodeineEsgic with Codeine, Fioricet w/ Codeine
How Acetaminophen, Butalbital, Caffeine, Codeine interacts with Super Strength Oregano 500 mg — through 1 ingredient. Tap an ingredient for the detail:
Sage (salvia Officinalis) ExtractCytochrome P450 3a4 (cyp3a4) Substrates, Cytochrome P450 2e1 (cyp2e1) Substrates +2 Moderate
Interaction Summary
Theoretically, sage might increase the levels and clinical effects of drugs metabolized by CYP3A4.
Read the full Sage (salvia Officinalis) Extract + Acetaminophen, Butalbital, Caffeine, Codeine interactionAcetaminophen, Butalbital, CodeineBancap w/ Codeine
How Acetaminophen, Butalbital, Codeine interacts with Super Strength Oregano 500 mg — through 1 ingredient. Tap an ingredient for the detail:
Sage (salvia Officinalis) ExtractCns Depressants, Cytochrome P450 2e1 (cyp2e1) Substrates +1 Moderate
Interaction Summary
Theoretically, taking sage might increase the sedative and adverse effects of CNS depressants.
Read the full Sage (salvia Officinalis) Extract + Acetaminophen, Butalbital, Codeine interactionAcetaminophen, Butalbital, Codeine PhosphatePhrenilin #3
How Acetaminophen, Butalbital, Codeine Phosphate interacts with Super Strength Oregano 500 mg — through 1 ingredient. Tap an ingredient for the detail:
Sage (salvia Officinalis) ExtractCns Depressants, Cytochrome P450 2e1 (cyp2e1) Substrates +1 Moderate
Interaction Summary
Theoretically, taking sage might increase the sedative and adverse effects of CNS depressants.
Read the full Sage (salvia Officinalis) Extract + Acetaminophen, Butalbital, Codeine Phosphate interactionAcetaminophen, Caffeine, Chlorpheniramine, Hydrocodone, PhenylephrineHycomine Compound
How Acetaminophen, Caffeine, Chlorpheniramine, Hydrocodone, Phenylephrine interacts with Super Strength Oregano 500 mg — through 1 ingredient. Tap an ingredient for the detail:
Sage (salvia Officinalis) ExtractCytochrome P450 2d6 (cyp2d6) Substrates, Cytochrome P450 2e1 (cyp2e1) Substrates +3 Moderate
Interaction Summary
Theoretically, sage might increase the levels and clinical effects of drugs metabolized by CYP2D6.
Read the full Sage (salvia Officinalis) Extract + Acetaminophen, Caffeine, Chlorpheniramine, Hydrocodone, Phenylephrine interactionAcetaminophen, Caffeine, CodeineGesic C15, Gesic C30, Gesic C8, Lenoltec 1, Lenoltec 2, Lenoltec 3 +1 more
How Acetaminophen, Caffeine, Codeine interacts with Super Strength Oregano 500 mg — through 1 ingredient. Tap an ingredient for the detail:
Sage (salvia Officinalis) ExtractCns Depressants, Cytochrome P450 2d6 (cyp2d6) Substrates +2 Moderate
Interaction Summary
Theoretically, taking sage might increase the sedative and adverse effects of CNS depressants.
Read the full Sage (salvia Officinalis) Extract + Acetaminophen, Caffeine, Codeine interactionAcetaminophen, Caffeine, Codeine, SalicylamideCodalan No.1, Codalan No.2, Codalan No.3
How Acetaminophen, Caffeine, Codeine, Salicylamide interacts with Super Strength Oregano 500 mg — through 1 ingredient. Tap an ingredient for the detail:
Sage (salvia Officinalis) ExtractCytochrome P450 3a4 (cyp3a4) Substrates, Cytochrome P450 2d6 (cyp2d6) Substrates +2 Moderate
Interaction Summary
Theoretically, sage might increase the levels and clinical effects of drugs metabolized by CYP3A4.
Read the full Sage (salvia Officinalis) Extract + Acetaminophen, Caffeine, Codeine, Salicylamide interactionAcetaminophen, Caffeine, DihydrocodeineDHC Plus, Panlor DC, Panlor SS
How Acetaminophen, Caffeine, Dihydrocodeine interacts with Super Strength Oregano 500 mg — through 1 ingredient. Tap an ingredient for the detail:
Sage (salvia Officinalis) ExtractCytochrome P450 2e1 (cyp2e1) Substrates, Cytochrome P450 2d6 (cyp2d6) Substrates +2 Moderate
Interaction Summary
Theoretically, sage might decrease the levels and clinical effects of drugs metabolized by CYP2E1.
Read the full Sage (salvia Officinalis) Extract + Acetaminophen, Caffeine, Dihydrocodeine interactionAcetaminophen, Caffeine, IsomethepteneMigralam
How Acetaminophen, Caffeine, Isometheptene interacts with Super Strength Oregano 500 mg — through 1 ingredient. Tap an ingredient for the detail:
Sage (salvia Officinalis) ExtractCytochrome P450 2e1 (cyp2e1) Substrates, Cytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, sage might decrease the levels and clinical effects of drugs metabolized by CYP2E1.
Read the full Sage (salvia Officinalis) Extract + Acetaminophen, Caffeine, Isometheptene interactionAcetaminophen, Caffeine, PyrilamineMidol Max Strength Menstrual
How Acetaminophen, Caffeine, Pyrilamine interacts with Super Strength Oregano 500 mg — through 1 ingredient. Tap an ingredient for the detail:
Sage (salvia Officinalis) ExtractCytochrome P450 3a4 (cyp3a4) Substrates, Anticholinergic Drugs +1 Moderate
Interaction Summary
Theoretically, sage might increase the levels and clinical effects of drugs metabolized by CYP3A4.
Read the full Sage (salvia Officinalis) Extract + Acetaminophen, Caffeine, Pyrilamine interactionAcetaminophen, Chlorpheniramine Maleate, Dextromethorphan HbrVicks Formula 44M Cough, Cold & Flu Relief
How Acetaminophen, Chlorpheniramine Maleate, Dextromethorphan Hbr interacts with Super Strength Oregano 500 mg — through 1 ingredient. Tap an ingredient for the detail:
Sage (salvia Officinalis) ExtractCytochrome P450 2e1 (cyp2e1) Substrates, Cytochrome P450 2d6 (cyp2d6) Substrates +2 Moderate
Interaction Summary
Theoretically, sage might decrease the levels and clinical effects of drugs metabolized by CYP2E1.
Read the full Sage (salvia Officinalis) Extract + Acetaminophen, Chlorpheniramine Maleate, Dextromethorphan Hbr interactionAcetaminophen, Chlorpheniramine, Codeine, PhenylephrineColrex
How Acetaminophen, Chlorpheniramine, Codeine, Phenylephrine interacts with Super Strength Oregano 500 mg — through 1 ingredient. Tap an ingredient for the detail:
Sage (salvia Officinalis) ExtractCytochrome P450 2e1 (cyp2e1) Substrates, Cytochrome P450 3a4 (cyp3a4) Substrates +3 Moderate
Interaction Summary
Theoretically, sage might decrease the levels and clinical effects of drugs metabolized by CYP2E1.
Read the full Sage (salvia Officinalis) Extract + Acetaminophen, Chlorpheniramine, Codeine, Phenylephrine interactionAcetaminophen, Chlorpheniramine, DextromethorphanCoricidin II Extra Strength Cold and Flu
How Acetaminophen, Chlorpheniramine, Dextromethorphan interacts with Super Strength Oregano 500 mg — through 1 ingredient. Tap an ingredient for the detail:
Sage (salvia Officinalis) ExtractCytochrome P450 2e1 (cyp2e1) Substrates, Anticholinergic Drugs +2 Moderate
Interaction Summary
Theoretically, sage might decrease the levels and clinical effects of drugs metabolized by CYP2E1.
Read the full Sage (salvia Officinalis) Extract + Acetaminophen, Chlorpheniramine, Dextromethorphan interactionAcetaminophen, Chlorpheniramine, Dextromethorphan HydrobromideCoricidin HBP Maximum Strength Flu
How Acetaminophen, Chlorpheniramine, Dextromethorphan Hydrobromide interacts with Super Strength Oregano 500 mg — through 1 ingredient. Tap an ingredient for the detail:
Sage (salvia Officinalis) ExtractCytochrome P450 2d6 (cyp2d6) Substrates, Cytochrome P450 2e1 (cyp2e1) Substrates +2 Moderate
Interaction Summary
Theoretically, sage might increase the levels and clinical effects of drugs metabolized by CYP2D6.
Read the full Sage (salvia Officinalis) Extract + Acetaminophen, Chlorpheniramine, Dextromethorphan Hydrobromide interactionEach ingredient & the kinds of drugs it affects
For each ingredient in Super Strength Oregano 500 mg with known interactions, here are the types of medications they can affect. Open any type for the detail — or search your exact drug in the checker above.
Sage (Salvia officinalis) extract
Anticholinergic Drugs
Theoretically, sage might decrease the clinical effects of anticholinergic drugs.
In vitro evidence suggests that common sage (Salvia officinalis) and Spanish sage (Salvia lavandulaefolia) can inhibit acetylcholinesterase and might increase acetylcholine levels.
Anticonvulsants
Theoretically, sage might interfere with the clinical effects of anticonvulsant drugs.
Some species of sage can cause convulsions when consumed in large quantities.
Antidiabetes Drugs
Theoretically, taking sage with antidiabetes drugs might increase the risk of hypoglycemia.
In patients with polycystic ovary syndrome (PCOS) or inadequately controlled type 2 diabetes, common sage (Salvia officinalis) has demonstrated hypoglycemic activity. However, other clinical research in patients with inadequately controlled type 2 diabetes shows that common sage extract does not lower fasting blood glucose levels.
Antihypertensive Drugs
Theoretically, sage might increase or decrease the effects of antihypertensive drugs.
Animal research suggests that common sage (Salvia officinalis) can cause prolonged blood pressure reduction. However, clinical research suggests that Spanish sage (Salvia lavandulaefolia) can increase blood pressure in some people with hypertension. Until more is known, use with caution.
Benzodiazepines
Theoretically, taking sage might increase the sedative and adverse effects of benzodiazepines.
In vitro evidence suggests that certain components of common sage (Salvia officinalis) can bind to benzodiazepine receptors. This effect has not been reported in humans.
Cholinergic Drugs
Theoretically, sage might have additive effects when used with cholinergic drugs.
In vitro evidence suggests that common sage (Salvia officinalis) and Spanish sage (Salvia lavandulaefolia) can inhibit acetylcholinesterase and might increase acetylcholine levels.
Cns Depressants
Theoretically, taking sage might increase the sedative and adverse effects of CNS depressants.
Some constituents of sage have CNS depressant activity.
Cytochrome P450 2C19 (Cyp2C19) Substrates
Theoretically, sage might increase the levels and clinical effects of drugs metabolized by CYP2C19.
In vitro evidence suggests that aqueous extracts of sage can inhibit CYP2C19. So far, this interaction has not been reported in humans.
Cytochrome P450 2C9 (Cyp2C9) Substrates
Theoretically, sage might increase the levels and clinical effects of drugs metabolized by CYP2C9.
In vitro evidence suggests that aqueous extracts of sage can inhibit CYP2C9. So far, this interaction has not been reported in humans.
Cytochrome P450 2D6 (Cyp2D6) Substrates
Theoretically, sage might increase the levels and clinical effects of drugs metabolized by CYP2D6.
In vitro evidence suggests that aqueous extracts of sage can inhibit CYP2D6. So far, this interaction has not been reported in humans.
Cytochrome P450 2E1 (Cyp2E1) Substrates
Theoretically, sage might decrease the levels and clinical effects of drugs metabolized by CYP2E1.
Animal research suggests that drinking common sage (Salvia officinalis) tea increases the expression of CYP2E1. So far, this interaction has not been reported in humans.
Cytochrome P450 3A4 (Cyp3A4) Substrates
Theoretically, sage might increase the levels and clinical effects of drugs metabolized by CYP3A4.
In vitro evidence suggests that aqueous extracts of sage can inhibit CYP3A4. So far, this interaction has not been reported in humans.
Estrogens
Theoretically, sage might interfere with hormone therapy.
In vitro evidence suggests that geraniol, a constituent of Spanish sage (Salvia lavandulaefolia), exerts estrogenic activity. The clinical significance of this effect is unclear.
P-Glycoprotein Substrates
Theoretically, sage might increase levels of drugs transported by P-glycoprotein.
In vitro research suggests that common sage (Salvia officinalis) can inhibit the multi-drug transporter protein, P-glycoprotein. This effect has not been reported in humans.
Oregano (Origanum vulgare) extract
Anticoagulant/Antiplatelet Drugs
Theoretically, oregano might increase the risk of bleeding when taken with anticoagulant or antiplatelet drugs.
In vitro research shows that aristolochic acid isolated from oregano leaves has antithrombin activity. It has also been reported that oregano oil inhibits arachidonic acid-induced, and ADP-induced, platelet aggregation.
Antidiabetes Drugs
Theoretically, oregano might increase the risk for hypoglycemia when taken with antidiabetes drugs.
In vitro and animal research shows that oregano extracts might lower blood glucose levels.
Brand information
Manufacturer and brand details for Super Strength Oregano 500 mg, from the product label.
Swanson Superior Herbs
See all Swanson Superior Herbs products- Name
- Swanson Health Products
- City
- Fargo
- State
- ND
- ZipCode
- 58104
- Phone Number
- 1-800-437-4148
- Web Address
- www.swansonvitamins.com
Super Strength Oregano 500 mg by Swanson Superior Herbs: Common Questions
Does Super Strength Oregano 500 mg by Swanson Superior Herbs interact with any medications?
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Where does this information come from?
Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
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The Full Monographs Behind Super Strength Oregano 500 mg’s Ingredients
Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.
Oregano
Interacts with 208 drugsOregano is a common Mediterranean cooking herb that is also sold as a concentrated oil or supplement, often standardized for a compound called carvacrol. While lab studies suggest it may hav...
Read the full Oregano monograph → Herb & supplement monographSage
Interacts with 1,296 drugsSage is a common kitchen herb that is generally safe in food amounts and is traditionally used for sore throats, digestion, sweating, and memory. Some early research is encouraging for sore...
Read the full Sage monograph →Sources & How We Checked
Super Strength Oregano 500 mg's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.
- NIH Dietary Supplement Label Database (DSLD) — The official product label on file for this supplement.
- Natural Medicines (Therapeutic Research Center) — Evidence-graded clinical reference behind the ingredient interaction data.
Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.
The 39 references behind this product’s interaction data
Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.
Oregano 12 references
- Brinker F. Herb Contraindications and Drug Interactions. 2nd ed. Sandy, OR: Eclectic Medical Publications, 1998.
- Benito M, Jorro G, Morales C, et al. Labiatae allergy: systemic reactions due to ingestion of oregano and thyme. Ann Allergy Asthma Immunol 1996;76:416-8. PubMed
- Chevallier A. Encyclopedia of Herbal Medicine. 2nd ed. New York, NY: DK Publ, Inc., 2000.
- Ciganda C, and Laborde A. Herbal infusions used for induced abortion. J Toxicol.Clin Toxicol. 2003;41:235-239. PubMed
- Futrell, J. M. and Rietschel, R. L. Spice allergy evaluated by results of patch tests. Cutis 1993;52(5):288-290.
- Tognolini, M., Barocelli, E., Ballabeni, V., Bruni, R., Bianchi, A., Chiavarini, M., and Impicciatore, M. Comparative screening of plant essential oils: phenylpropanoid moiety as basic core for antiplatelet activity. Life Sci. 2-23-2006;78(13):1419-1432. PubMed
- Goun, E., Cunningham, G., Solodnikov, S., Krasnykch, O., and Miles, H. Antithrombin activity of some constituents from Origanum vulgare. Fitoterapia 2002;73(7-8):692-694. PubMed
- Lemhadri, A., Zeggwagh, N. A., Maghrani, M., Jouad, H., and Eddouks, M. Anti-hyperglycaemic activity of the aqueous extract of Origanum vulgare growing wild in Tafilalet region. J Ethnopharmacol. 2004;92(2-3):251-256. PubMed
- McCue, P., Vattem, D., and Shetty, K. Inhibitory effect of clonal oregano extracts against porcine pancreatic amylase in vitro. Asia Pac.J Clin.Nutr. 2004;13(4):401-408.
- Ragi, J., Pappert, A., Rao, B., Havkin-Frenkel, D., and Milgraum, S. Oregano extract ointment for wound healing: a randomized, double-blind, petrolatum-controlled study evaluating efficacy. J.Drugs Dermatol. 2011;10(10):1168-1172.
- Singletary K. Oregano: overview of the literature on health benefits. Nutrition Today 2010;45(3):129-38.
- Silva MLAE, Lucarini R, Dos Santos FF, et al. Hypoglycemic effect of rosmarinic acid-rich infusion (RosCE) from Origanum vulgare in alloxan-induced diabetic rats. Nat Prod Res 2022;36(17):4525-4531.
Sage 27 references
- Brinker F. Herb Contraindications and Drug Interactions. 2nd ed. Sandy, OR: Eclectic Medical Publications, 1998.
- Todorov S, Philianos S, Petkov V, et al. Experimental pharmacological study of three species from genus Salvia. Acta Physiol Pharmacol (Bulg) 1984;10:13-20.
- Perry NS, Bollen C, Perry EK, Ballard C. Salvia for dementia therapy: review of pharmacological activity and pilot tolerability clinical trial. Pharmacol Biochem Behav 2003;75:651-9.. PubMed
- Saller R, Buechi S, Meyrat R, Schmidhauser C. Combined herbal preparation for topical treatment of Herpes labialis. Forsch Komplementarmed Klass Naturheilkd 2001;8:373-82. PubMed
- Akhondzadeh S, Noroozian M, Mohammadi M, et al. Salvia officinalis extract in the treatment of patients with mild to moderate Alzheimer's disease: a double blind, randomized and placebo-controlled trial. J Clin Pharm Ther 2003;28:53-9.
- Perry NB, Anderson RE, Brennan NJ, et al. Essential oils from dalmatian sage (Salvia officinalis l.): variations among individuals, plant parts, seasons, and sites. J Agric Food Chem 1999;47:2048-54..
- Foster BC, Vandenhoek S, Hana J, et al. In vitro inhibition of human cytochrome P450-mediated metabolism of marker substrates by natural products. Phytomedicine 2003;10:334-42.. PubMed
- Burkhard PR, Burkhardt K, Haenggeli CA, Landis T. Plant-induced seizures: reappearance of an old problem. J Neurol 1999;246:667-70. PubMed
- Bommer S, Klein P, Suter A. First time proof of sage's tolerability and efficacy in menopausal women with hot flushes. Adv Ther 2011;28:490-500. PubMed
- Hellum BH, Nilsen OG. The in vitro inhibitory potential of trade herbal products on human CYP2D6-mediated metabolism and the influence of ethanol. Basic Clin Pharmacol Toxicol. 2007 Nov;101:350-8.
- Orhan, I., Kartal, M., Kan, Y., and Sener, B. Activity of essential oils and individual components against acetyl- and butyrylcholinesterase. Z.Naturforsch.C. 2008;63(7-8):547-553.
- Perry, N. S., Houghton, P. J., Theobald, A., Jenner, P., and Perry, E. K. In-vitro inhibition of human erythrocyte acetylcholinesterase by salvia lavandulaefolia essential oil and constituent terpenes. J Pharm Pharmacol 2000;52(7):895-902.
- Perry, N. S., Houghton, P. J., Sampson, J., Theobald, A. E., Hart, S., Lis-Balchin, M., Hoult, J. R., Evans, P., Jenner, P., Milligan, S., and Perry, E. K. In-vitro activity of S. lavandulaefolia (Spanish sage) relevant to treatment of Alzheimer's diseas
- Futrell, J. M. and Rietschel, R. L. Spice allergy evaluated by results of patch tests. Cutis 1993;52(5):288-290.
- Kavvadias, D., Monschein, V., Sand, P., Riederer, P., and Schreier, P. Constituents of sage (Salvia officinalis) with in vitro affinity to human brain benzodiazepine receptor. Planta Med. 2003;69(2):113-117.
- Savelev, S. U., Okello, E. J., and Perry, E. K. Butyryl- and acetyl-cholinesterase inhibitory activities in essential oils of Salvia species and their constituents. Phytother Res 2004;18(4):315-324.
- Kennedy, D. O., Pace, S., Haskell, C., Okello, E. J., Milne, A., and Scholey, A. B. Effects of cholinesterase inhibiting sage (Salvia officinalis) on mood, anxiety and performance on a psychological stressor battery. Neuropsychopharmacology 2006;31(4):84 PubMed
- Hubbert, M., Sievers, H., Lehnfeld, R., and Kehrl, W. Efficacy and tolerability of a spray with Salvia officinalis in the treatment of acute pharyngitis - a randomised, double-blind, placebo-controlled study with adaptive design and interim analysis. Eur
- Lima, C. F., Fernandes-Ferreira, M., and Pereira-Wilson, C. Drinking of Salvia officinalis tea increases CCl(4)-induced hepatotoxicity in mice. Food Chem.Toxicol. 2007;45(3):456-464.
- Hellum, B. H. and Nilsen, O. G. In vitro inhibition of CYP3A4 metabolism and P-glycoprotein-mediated transport by trade herbal products. Basic Clin Pharmacol Toxicol. 2008;102(5):466-475.
- Mayer, E., Gescheidt-Shoshany, H., and Weltfriend, S. Allergic contact dermatitis caused by Salvia officinalis extract. Contact Dermatitis 2011;64(4):237-238. PubMed
- Halicioglu, O., Astarcioglu, G., Yaprak, I., and Aydinlioglu, H. Toxicity of Salvia officinalis in a newborn and a child: an alarming report. Pediatr.Neurol. 2011;45(4):259-260. PubMed
- Sertoli, A., Fabbri, P., Campolmi, P., and Panconesi, E. Allergic contact dermatitis to Salvia Officinalis, Inula Viscosa and Conyza Bonariensis. Contact Dermatitis 1978;4(5):314-315.
- Vandecasteele K, Ost P, Oosterlinck W, et al. Evaluation of the efficacy and safety of Salvia officinalis in controlling hot flashes in prostate cancer patients treated with androgen deprivation. Phytother Res. 2012;26(2):208-13.
- Kianbakht S, Dabaghian FH. Improved glycemic control and lipid profile in hyperlipidemic type 2 diabetic patients consuming Salvia officinalis L. leaf extract: a randomized placebo. Controlled clinical trial. Complement Ther Med. 2013;21(5):441-6. PubMed
- Amini L, Mojab F, Jahanfar S, Sepidarkish M, Raoofi Z, Maleki-Hajiagha A. Efficacy of Salvia officinalis extract on the prevention of insulin resistance in euglycemic patients with polycystic ovary syndrome: A double-blinded placebo-controlled clinical tr
- Behradmanesh S, Derees F, Rafieian-Kopaei M. Effect of Salvia officinalis on diabetic patients. J Renal Inj Prev. 2013;2(2):51-4.
Parts of this content are provided by the Therapeutic Research Center, LLC.
DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.
© 2021 Therapeutic Research Center, LLC