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Dietary supplement

SuperPure Oregano Ingredients & Drug Interactions

by Pure Synergy

SuperPure Oregano label
See full label image
Capsule Category: Botanical
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 16, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking SuperPure Oregano against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

SuperPure Oregano is a dietary supplement by Pure Synergy with 1 active ingredient. Its ingredients are commonly taken for digestive upset, respiratory and cold symptoms, antimicrobial support.Based on those ingredients, 208 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are organic, SuperPure Oregano. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

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Check Your Meds Against SuperPure Oregano by Pure Synergy

Ask about any prescription or over-the-counter medication and we check it for interactions with SuperPure Oregano by Pure Synergy — and tell you which ingredient is responsible.

Pharmacist-reviewed data Checks every ingredient Answer in seconds
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HelloPharmacist Scorecard of SuperPure Oregano by Pure Synergy

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Jul 11, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 2 of its 2 active ingredients.
  • “organic, SuperPure Oregano” is listed as a grouped ingredient — the label gives one combined amount (350 mg) without saying how much of each component you get.
  • “certified organic Oregano Oil CO2 extract” is listed as a grouped ingredient — the label gives one combined amount (300 mg) without saying how much of each component you get.

SuperPure Oregano delivers 2 active ingredients: carvacrol and certified organic oregano (supplied as a fresh herb, an oil CO2 extract, and a blend component). The product is capsule form with a vegetarian capsule as the only inactive ingredient.

Does it work?

Not established
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not established

The graded evidence we hold for these ingredients covers different conditions than the ones this product is marketed for, so there's no established rating for its stated use — see Oregano's own graded uses on its monograph.

Why this rating?
  • The label markets this product for: Immune support and healthy microbial balance.
  • We looked for evidence on: Upper respiratory tract infection (URTI), Bronchitis, Cough, Rhinosinusitis, Intestinal parasite infection, Immune function — and 2 related terms.
  • The closest evidence on file: Oregano is rated "Insufficient Reliable Evidence To Rate" for Bronchitis (Natural Medicines).
  • Also on file: Oregano is rated "Insufficient Reliable Evidence To Rate" for Upper respiratory tract infection (URTI), Cough, Intestinal parasite infection, Rhinosinusitis.

The evidence isn't established for oregano in this product. The data we hold rates it insufficient reliable evidence for acne, bronchitis, asthma, headache, and upper respiratory tract infection — meaning there aren't enough rigorous studies to say whether it works for these uses.

The evidence, ingredient by ingredient Oregano

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Oregano is well tolerated in food amounts. As a supplement — especially oregano oil — it's stronger and less studied, so caution applies.

In trials, the most common side effect was stomach upset. Rarely, allergic reactions (including anaphylaxis) and contact skin inflammation have been reported, mostly in sensitive individuals.

Oregano oil at over 1% concentration can irritate mucous membranes. During pregnancy, avoid medicinal or supplement amounts; food seasoning is likely fine.

While breastfeeding, stick to normal food amounts — the safety of supplements isn't established, so talk with your pharmacist or doctor for personalized guidance.

Side effects, ingredient by ingredient Oregano

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Oregano.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: anticoagulant / antiplatelet drugs; diabetes medications.
  • For scale: 208 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before taking SuperPure Oregano, check with your pharmacist if you're on blood thinners or antiplatelet drugs (warfarin, aspirin, clopidogrel, etc.) — oregano may increase bleeding risk. Also check diabetes medications — oregano may lower blood sugar too far.

These are Moderate-severity interactions.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with no established evidence rating for its marketed use. Moderate medication interactions have been identified, and safety information is well characterized.

This product is for people interested in oregano's traditional uses, though rigorous evidence is limited. If you take blood thinners, diabetes medications, or any prescription drugs, check them against the interaction tool first.

Talk to your pharmacist before starting, especially if you have a history of allergies to oregano or other herbs in the mint family (like thyme).

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 2 of 2 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Apr 22, 2021.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about SuperPure Oregano, straight from the product label.

Brand Pure Synergy
Barcode (UPC) 852971004828
Net contents 60 Capsule(s)
Market status On market
Date entered into DSLD Apr 22, 2021
DSLD ID 246691
Product type Botanical
Supplement form Capsule
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years), Kosher, Organic, Gluten Free, Dairy Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for SuperPure Oregano by Pure Synergy, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Capsule(s)
Maximum serving Sizes:
1 Capsule(s)
Servings per container
60
UPC/BARCODE
852971004828
IngredientAmount% DV
Carvacrol36 mg--
organic, SuperPure Oregano350 mg--
certified organic Oregano Oil CO2 extract300 mg--
certified organic Oregano50 mg--

Other ingredients: Vegetarian Capsule

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Formulation

Immune Support

Oregon Tilth Certified Organic (OTCO)

Non GMO

No GMO's, dairy or gluten

Formula

SuperPure Oregano supports healthy microbial balance throughout your whole body, and enhances your natural defenses for a healthy immune response. Our high potency, certified organic CO2 extraction method concentrates the beneficial active compounds of this powerful herb.

OU (Kosher) Certified Kosher

Made with organic Oregano extract

SuperPure

Suggested/Recommended/Usage/Directions

Suggested Use: 1 capsule once or twice daily with or without food. For extended use, please speak with your qualified healthcare professional.

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

Seals/Symbols

Oregon Tilth Certified Organic (OTCO) OU (Kosher) Certified Kosher

Oregon Tilth Certified Organic (OTCO)

FDA Statement of Identity

Dietary Supplement

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

SuperPure Oregano by Pure Synergy label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

SuperPure Oregano label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in SuperPure Oregano by Pure Synergy

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size1 Capsule(s) Dosage formCapsule Servings per container60 Amounts shown are per serving.

Organic, SuperPure Oregano

Interacts with
208 drugs
350 mg per serving

Oregano is a common Mediterranean cooking herb that is also sold as a concentrated oil or supplement, often standardized for a compound called carvacr...

Organic, SuperPure Oregano monograph & interactions

Other (inactive) ingredients: Vegetarian Capsule. These complete the product’s ingredient list but are not active constituents.

Interaction report

SuperPure Oregano by Pure Synergy Drug Interactions

Want to check YOUR meds against SuperPure Oregano?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
208Drugs
208 Moderate

Ingredients driving the most interactions

organic, SuperPure Oregano 208

Individual Drug Interactions

The ingredients in SuperPure Oregano interact with 208 drugs. Click any drug to see the details.

1 of the 1 ingredient in SuperPure Oregano interact with drugs. Each result below shows which ingredient is responsible. organic, SuperPure Oregano

Each ingredient & the kinds of drugs it affects

For each ingredient in SuperPure Oregano with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

organic, SuperPure Oregano2 drug types · 208 drugs

Anticoagulant/Antiplatelet Drugs

Theoretically, oregano might increase the risk of bleeding when taken with anticoagulant or antiplatelet drugs.
In vitro research shows that aristolochic acid isolated from oregano leaves has antithrombin activity. It has also been reported that oregano oil inhibits arachidonic acid-induced, and ADP-induced, platelet aggregation.

Likelihood Possible Evidence D
Antidiabetes Drugs

Theoretically, oregano might increase the risk for hypoglycemia when taken with antidiabetes drugs.
In vitro and animal research shows that oregano extracts might lower blood glucose levels.

Likelihood Possible Evidence D
organic, SuperPure Oregano full monograph & interactions
The maker

Brand information

Manufacturer and brand details for SuperPure Oregano, from the product label.

Pure Synergy

See all Pure Synergy products
Name
The Synergy Company
City
Moab
State
Utah
ZipCode
84532
Phone Number
800-723-0277
Web Address
thesynergycompany.com
Pharmacist Counseling Corner

SuperPure Oregano by Pure Synergy: Common Questions

Does SuperPure Oregano by Pure Synergy interact with any medications?
Yes. Based on its ingredients, SuperPure Oregano has a known interaction with 208 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
SuperPure Oregano contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Can I take this if I'm on a blood thinner like warfarin?
Not without checking with your pharmacist first. Oregano may raise your bleeding risk when combined with blood thinners or antiplatelet drugs. Bring your medication list to the pharmacy before starting.
Is oregano safe during pregnancy?
Avoid medicinal or supplement amounts during pregnancy. Food amounts — like seasoning on your dinner — are likely fine. Talk with your pharmacist or doctor if you're pregnant and considering a supplement.
What's the difference between cooking with oregano and taking this supplement?
When you cook with oregano, you're using tiny amounts. This supplement is a concentrated extract, which is stronger and much less studied for safety. That's why we're more cautious with the supplement form.
Can this cause an allergic reaction?
Rarely, yes — oregano can trigger serious allergic reactions, including anaphylaxis, in sensitive people, especially those allergic to herbs in the mint family like thyme. If you have a history of herb allergies, talk to your pharmacist before using this.
What side effects might I notice?
Most common is stomach upset. Contact skin inflammation (dermatitis) can occur, especially if oregano oil touches your skin. Systemic allergic reactions are rare but serious.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if SuperPure Oregano is safe with your meds?

Our pharmacists answer your medication & supplement questions — free.

Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

SuperPure Oregano label
Go deeper

The Full Monographs Behind SuperPure Oregano’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Oregano

Interacts with 208 drugs

Oregano is a common Mediterranean cooking herb that is also sold as a concentrated oil or supplement, often standardized for a compound called carvacrol. While lab studies suggest it may hav...

Read the full Oregano monograph →
Sources

Sources & How We Checked

SuperPure Oregano's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 12 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Oregano 12 references
  1. Brinker F. Herb Contraindications and Drug Interactions. 2nd ed. Sandy, OR: Eclectic Medical Publications, 1998.
  2. Benito M, Jorro G, Morales C, et al. Labiatae allergy: systemic reactions due to ingestion of oregano and thyme. Ann Allergy Asthma Immunol 1996;76:416-8. PubMed
  3. Chevallier A. Encyclopedia of Herbal Medicine. 2nd ed. New York, NY: DK Publ, Inc., 2000.
  4. Ciganda C, and Laborde A. Herbal infusions used for induced abortion. J Toxicol.Clin Toxicol. 2003;41:235-239. PubMed
  5. Futrell, J. M. and Rietschel, R. L. Spice allergy evaluated by results of patch tests. Cutis 1993;52(5):288-290.
  6. Tognolini, M., Barocelli, E., Ballabeni, V., Bruni, R., Bianchi, A., Chiavarini, M., and Impicciatore, M. Comparative screening of plant essential oils: phenylpropanoid moiety as basic core for antiplatelet activity. Life Sci. 2-23-2006;78(13):1419-1432. PubMed
  7. Goun, E., Cunningham, G., Solodnikov, S., Krasnykch, O., and Miles, H. Antithrombin activity of some constituents from Origanum vulgare. Fitoterapia 2002;73(7-8):692-694. PubMed
  8. Lemhadri, A., Zeggwagh, N. A., Maghrani, M., Jouad, H., and Eddouks, M. Anti-hyperglycaemic activity of the aqueous extract of Origanum vulgare growing wild in Tafilalet region. J Ethnopharmacol. 2004;92(2-3):251-256. PubMed
  9. McCue, P., Vattem, D., and Shetty, K. Inhibitory effect of clonal oregano extracts against porcine pancreatic amylase in vitro. Asia Pac.J Clin.Nutr. 2004;13(4):401-408.
  10. Ragi, J., Pappert, A., Rao, B., Havkin-Frenkel, D., and Milgraum, S. Oregano extract ointment for wound healing: a randomized, double-blind, petrolatum-controlled study evaluating efficacy. J.Drugs Dermatol. 2011;10(10):1168-1172.
  11. Singletary K. Oregano: overview of the literature on health benefits. Nutrition Today 2010;45(3):129-38.
  12. Silva MLAE, Lucarini R, Dos Santos FF, et al. Hypoglycemic effect of rosmarinic acid-rich infusion (RosCE) from Origanum vulgare in alloxan-induced diabetic rats. Nat Prod Res 2022;36(17):4525-4531.

See these in context on the Oregano monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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