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Dietary supplement

Sync Up Berry Flavor Ingredients & Drug Interactions

by Little DaVinci

Sync Up Berry Flavor label
See full label image
Liquid Category: Botanical
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 16, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Sync Up Berry Flavor against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Sync Up Berry Flavor is a dietary supplement by Little DaVinci with 1 active ingredient. Its ingredients are commonly taken for general nutrition and antioxidant support, heart and digestive health, detoxification support.Based on those ingredients, 723 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are BroccoPhane. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

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Check Your Meds Against Sync Up Berry Flavor by Little DaVinci

Ask about any prescription or over-the-counter medication and we check it for interactions with Sync Up Berry Flavor by Little DaVinci — and tell you which ingredient is responsible.

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HelloPharmacist Scorecard of Sync Up Berry Flavor by Little DaVinci

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Jul 11, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • “BroccoPhane” is listed as a grouped ingredient — the label gives one combined amount (93.75 mg) without saying how much of each component you get.

Sync Up Berry Flavor has one active ingredient: sulforaphane, a compound found in cruciferous vegetables like broccoli that's being studied for potential health effects. The product also contains several inactive ingredients — glycerin, water, oils, bilberry extract, and others that help create the formula and improve taste and shelf life.

Does it work?

Moderate evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed

This product doesn't appear to be marketed for a specific use, so we graded Sulforaphane's overall clinical evidence instead.

Moderate

Some clinical evidence supports Sulforaphane for:

Why this rating?
  • We looked at the product name, claims, and label statements and couldn't find a stated purpose to grade.
  • Since the label doesn't commit to one use, we graded the ingredient's overall clinical evidence instead.
  • On file: Prostate cancer — rated "Possibly Effective" (Natural Medicines).

The evidence for sulforaphane's effectiveness varies by condition. It's rated possibly effective for prostate cancer based on available research.

For hay fever (allergic rhinitis) and asthma, there isn't enough reliable evidence yet to know whether it works. Cancer in general has insufficient evidence to rate.

The data we hold doesn't cover all the conditions sulforaphane might be marketed for, so if you're curious about a specific use, ask your pharmacist or doctor what the research actually shows.

The evidence, ingredient by ingredient Broccoli Sulforaphane

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Sulforaphane from food is considered safe, but concentrated supplements like this one are less studied over the long term. The most common side effects reported are bowel discomfort, heartburn, stomach upset, and vomiting.

In clinical studies, some people also reported headache, insomnia, and irritability. There have been two reported cases of seizure in males with autism taking sulforaphane — one occurred after 3 weeks of use in someone with a recent seizure history, and another broke through existing seizure control.

One study also noted increased weight gain (about 4 pounds more over 18 weeks) in young males with autism. For pregnancy, the safety data advises against concentrated sulforaphane supplements — stick to normal food amounts instead.

While breastfeeding, there isn't enough information on supplement-level doses, so use caution and prefer dietary amounts. If you're pregnant or breastfeeding, talk with your doctor or pharmacist before adding this product.

Side effects, ingredient by ingredient Broccoli Sulforaphane

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Sulforaphane.
  • The most serious interaction on file is rated Moderate.
  • For scale: 723 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Check your medications against this product if you take drugs broken down by your liver's CYP3A4, CYP1A2, or CYP2E1 enzymes — sulforaphane may change how your body processes them. This includes many common medications.

If you have a seizure disorder or history of seizures, talk with your doctor or pharmacist before using this product.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with some supporting evidence behind its ingredients' uses. Moderate medication interactions have been identified, and safety information is well characterized.

Sulforaphane is most studied for prostate cancer support, though evidence is still developing. If you take any prescription or regular over-the-counter medication — especially ones that affect your liver — you'll need to check them against this product before starting.

The side effects are usually mild digestive upset, but seizure risk in certain populations and long-term safety in supplements warrant a conversation with your pharmacist.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Dec 14, 2023.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Sync Up Berry Flavor, straight from the product label.

Brand Little DaVinci
Barcode (UPC) 026664014153
Net contents 2 Fluid Ounce(s); 60 mL
Market status On market
Date entered into DSLD Dec 14, 2023
DSLD ID 303898
Product type Botanical
Supplement form Liquid
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Children 4 or More Years of Age, Vegetarian, Gluten Free, Dairy Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Sync Up Berry Flavor by Little DaVinci, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Milliliter(s)
Maximum serving Sizes:
1 Milliliter(s)
Servings per container
60
UPC/BARCODE
026664014153
IngredientAmount% DV
Total Carbohydrates1 Gram(s)--
Sulforaphane375 mcg--
BroccoPhane93.75 mg--

Other ingredients: Glycerin, Water, Oleic Acid Polyglyceride, Natural Flavors, Sunflower Lecithin, Sunflower Oil, Bilberry Extract, Xanthan Gum, Potassium Citrate, Mixed Tocopherols, Rosmarinic Acid

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Suggested/Recommended/Usage/Directions

Suggested Use: As a dietary supplement, children 4 and older take 1 ml in AM and PM, or as directed by your healthcare practitioner. Shake well before each use.

Formulation

Color, flavor and sweetness of this product may vary due to variations of natural ingredients.

Gluten free Soy free Dairy free

Vegetarian

Brain + development support

Precautions

Warning: If your child has any health conditions, consult your healthcare practitioner before taking this product.

Caution: Do not put glass dropper directly in mouth.

Keep out of reach of children.

To obtain product information or report a serious adverse event, call 1-800-325-1776.

Storage

Store in a cool, dry place.

Best if used within 60 days of opening.

Brand IP Statement(s)

BroccoPhane is a registered trademark of Cyvex Nutrition, Inc.

FDA Disclaimer Statement

This statement has not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

General Statements

Doctor formulated

Formula

BroccoPhane Broccoli-sprout powder

FDA Statement of Identity

Dietary Supplement

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Sync Up Berry Flavor by Little DaVinci label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Sync Up Berry Flavor label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Sync Up Berry Flavor by Little DaVinci

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size1 Milliliter(s) Dosage formLiquid Servings per container60 Amounts shown are per serving.

BroccoPhane

Interacts with
187 drugs
93.75 mg per serving Form: Broccoli, Powder

Broccoli is a nutritious cruciferous vegetable rich in fiber, vitamins, and plant compounds like sulforaphane that have drawn scientific interest for...

BroccoPhane monograph & interactions

Other (inactive) ingredients: Glycerin, Water, Oleic Acid Polyglyceride, Natural Flavors, Sunflower Lecithin, Sunflower Oil, Bilberry Extract, Xanthan Gum, Potassium Citrate, Mixed Tocopherols, Rosmarinic Acid. These complete the product’s ingredient list but are not active constituents.

Interaction report

Sync Up Berry Flavor by Little DaVinci Drug Interactions

Want to check YOUR meds against Sync Up Berry Flavor?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
723Drugs
723 Moderate

Ingredients driving the most interactions

BroccoPhane 187

Individual Drug Interactions

The ingredients in Sync Up Berry Flavor interact with 723 drugs. Click any drug to see the details.

1 of the 1 ingredient in Sync Up Berry Flavor interact with drugs. Each result below shows which ingredient is responsible. BroccoPhane

Each ingredient & the kinds of drugs it affects

For each ingredient in Sync Up Berry Flavor with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

BroccoPhane2 drug types · 187 drugs

Cytochrome P450 1A2 (Cyp1A2) Substrates

Theoretically, broccoli might reduce the levels and effects of drugs metabolized by CYP1A2.
Pharmacokinetic research in humans shows that eating 500 grams of fresh broccoli daily for 6-12 days can increase CYP1A2 activity by 10% to 200%. Induction of CYP1A2 activity by broccoli is attributed to its glucosinolate constituents.

Likelihood Possible Evidence B
Cytochrome P450 2A6 (Cyp2A6) Substrates

Theoretically, broccoli might reduce the levels and effects of drugs metabolized by CYP2A6.
Pharmacokinetic research in humans shows that eating 500 grams of broccoli daily for 6 days increases CYP2A6 activity by 135% to 550%. Induction of CYP2A6 activity is attributed to its glucosinolate constituents.

Likelihood Possible Evidence B
BroccoPhane full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Sync Up Berry Flavor, from the product label.

Little DaVinci

See all Little DaVinci products
Name
DaVinci Laboratories a division of FoodScience LLC
Street Address
929 Harvest Lane
City
Williston
State
VT
ZipCode
05495
Phone Number
1-800-325-1776
Web Address
www.davincilabs.com
Pharmacist Counseling Corner

Sync Up Berry Flavor by Little DaVinci: Common Questions

Does Sync Up Berry Flavor by Little DaVinci interact with any medications?
Yes. Based on its ingredients, Sync Up Berry Flavor has a known interaction with 723 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Sync Up Berry Flavor contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
What is sulforaphane and why is it in this product?
Sulforaphane is a compound from cruciferous vegetables like broccoli. This product concentrates it for supplement form. It's been studied for several health conditions, most notably prostate cancer, though research is still underway on many uses.
Is this safe to take while I'm pregnant or breastfeeding?
Concentrated sulforaphane supplements haven't been proven safe in pregnancy, so the data advises against them — stick to normal food amounts instead. While breastfeeding, there isn't enough information on supplement doses, so use caution and prefer dietary amounts. Talk with your doctor or pharmacist for personalized advice.
What side effects might I experience?
The most common are bowel discomfort, heartburn, stomach upset, and vomiting. Some people have reported headache, insomnia, and irritability in studies. There's also a reported risk of seizure in certain populations, and one study noted weight gain of about 4 pounds over 18 weeks in young males with autism.
Does sulforaphane actually work for the conditions it's marketed for?
It's rated possibly effective for prostate cancer. For hay fever and asthma, there isn't enough reliable evidence yet to know whether it helps. For cancer in general, evidence is insufficient to rate. Ask your pharmacist or doctor what research supports the specific use you're interested in.
Why do I need to check my medications before taking this?
Sulforaphane affects how your liver breaks down certain drugs by inhibiting three major enzymes. This can increase drug levels and effects, which may make medications too strong or change how well they work. You'll want to make sure none of your prescriptions or over-the-counter drugs are on that list.
What exactly is BroccoPhane, the other ingredient listed?
BroccoPhane is listed as a blend or group container, which means its component ingredients are listed individually elsewhere on the label or in the full ingredients list. It's not a separate active ingredient beyond what's already accounted for in the sulforaphane.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Sync Up Berry Flavor is safe with your meds?

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Sync Up Berry Flavor label
Go deeper

The Full Monographs Behind Sync Up Berry Flavor’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Broccoli

Interacts with 187 drugs

Broccoli is a nutritious cruciferous vegetable rich in fiber, vitamins, and plant compounds like sulforaphane that have drawn scientific interest for health benefits. Eating broccoli as food...

Read the full Broccoli monograph → Herb & supplement monograph

Sulforaphane

Interacts with 722 drugs

Sulforaphane is a natural compound found in broccoli and other cruciferous vegetables that has shown promising antioxidant and anti-inflammatory effects in lab studies, but strong human evid...

Read the full Sulforaphane monograph →
Sources

Sources & How We Checked

Sync Up Berry Flavor's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 21 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Sulforaphane 16 references
  1. Park EJ, Pezzuto JM. Botanicals in cancer chemoprevention. Cancer Metastasis Rev 2002;21:231-55. PubMed
  2. Barcelo S, Mace K, Pfeifer AM, Chipman JK. Production of DNA strand breaks by N-nitrosodimethylamine and 2-amino-3-methylimidazo[4,5-f]quinoline in THLE cells expressing human CYP isoenzymes and inhibition by sulforaphane. Mutat Res 1998;402:111-20. PubMed
  3. Cipolla BG, Mandron E, Lefort JM, et al. Effect of sulforaphane in men with biochemical recurrence after radical prostatectomy. Cancer Prev Res (Phila). 2015;8(8):712-9. PubMed
  4. Fahey JW, Wade KL, Wehage SL, et al. Stabilized sulforaphane for clinical use: Phytochemical delivery efficiency. Mol Nutr Food Res. 2017 Apr;61(4). PubMed
  5. Alumkal JJ, Slottke R, Schwartzman J, et al. A phase II study of sulforaphane-rich broccoli sprout extracts in men with recurrent prostate cancer. Invest New Drugs. 2015;33(2):480-9. PubMed
  6. Heber D, Li Z, Garcia-Lloret M, et al. Sulforaphane-rich broccoli sprout extract attenuates nasal allergic response to diesel exhaust particles. Food Funct. 2014;5(1):35-41. PubMed
  7. Singh K, Connors SL, Macklin EA, et al. Sulforaphane treatment of autism spectrum disorder (ASD). Proc Natl Acad Sci U S A. 2014;111(43):15550-5. PubMed
  8. Wise RA, Holbrook JT, Criner G, et al. Lack of effect of oral sulforaphane administration on Nrf2 expression in COPD: A randomized, double-blind, placebo controlled trial. PLoS One. 2016;11(11):e0163716. PubMed
  9. Bent S, Lawton B, Warren T, et al. Identification of urinary metabolites that correlate with clinical improvements in children with autism treated with sulforaphane from broccoli. Mol Autism. 2018;9:35. PubMed
  10. Momtazmanesh S, Amirimoghaddam-Yazdi Z, Moghaddam HS, Mohammadi MR, Akhondzadeh S. Sulforaphane as an adjunctive treatment for irritability in children with autism spectrum disorder: A randomized, double-blind, placebo-controlled clinical trial. Psychiatr PubMed
  11. Fimognari C, Lenzi M, Hrelia P. Interaction of the isothiocyanate sulforaphane with drug disposition and metabolism: pharmacological and toxicological implications. Curr Drug Metab. 2008;9(7):668-78. PubMed
  12. Chinnappan SM, George A, Evans M, Anthony J. Efficacy of Labisia pumila and Eurycoma longifolia standardised extracts on hot flushes, quality of life, hormone and lipid profile of peri-menopausal and menopausal women: a randomised, placebo-controlled stud
  13. Mahéo K, Morel F, Langouët S, et al. Inhibition of cytochromes P-450 and induction of glutathione S-transferases by sulforaphane in primary human and rat hepatocytes. Cancer Res. 1997;57(17):3649-52.
  14. Yoxall V, Kentish P, Coldham N, Kuhnert N, Sauer MJ, Ioannides C. Modulation of hepatic cytochromes P450 and phase II enzymes by dietary doses of sulforaphane in rats: Implications for its chemopreventive activity. Int J Cancer. 2005;117(3):356-62. PubMed
  15. Zimmerman AW, Singh K, Connors SL, et al. Randomized controlled trial of sulforaphane and metabolite discovery in children with Autism Spectrum Disorder. Mol Autism 2021;12(1):38.
  16. Yusin J, Wang V, Henning SM, et al. The effect of broccoli sprout extract on seasonal grass pollen-induced allergic rhinitis. Nutrients 2021;13(4):1337. PubMed

See these in context on the Sulforaphane monograph →

Broccoli 5 references
  1. Kristal AR, Lampe JW. Brassica vegetables and prostate cancer risk: a review of the epidemiological evidence. Nutr Cancer 2002;42:1-9. PubMed
  2. Chakrabarti A, Prais L, Foulds IS. Allergic contact dermatitis to broccoli. Br J Dermatol 2003;148:172-3. PubMed
  3. Hakooz, N. and Hamdan, I. Effects of dietary broccoli on human in vivo caffeine metabolism: a pilot study on a group of Jordanian volunteers. Curr Drug Metab 2007;8(1):9-15. PubMed
  4. Kall MA, Vang O, Clausen J. Effects of dietary broccoli on human drug metabolising activity. Cancer Lett. 1997;114(1-2):169-70. PubMed
  5. Bauman JE, Hsu CH, Centuori S, et al. Randomized Crossover Trial Evaluating Detoxification of Tobacco Carcinogens by Broccoli Seed and Sprout Extract in Current Smokers. Cancers (Basel). 2022;14(9):2129. Published 2022 Apr 24. PubMed

See these in context on the Broccoli monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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