Major interaction on record — check this product against your medications before combining. Based on 3 of 4 ingredients. Check your meds →
Dietary supplement

Ultimate Flora Probiotic Advanced Immunity 10 Billion Ingredients & Drug Interactions

by Renew Life

Ultimate Flora Probiotic Advanced Immunity 10 Billion label
See full label image
Capsule Category: Other Combinations
Most serious interaction: Major
Clinical methodology reviewed by · Updated Sep 23, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Ultimate Flora Probiotic Advanced Immunity 10 Billion against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Major

Ultimate Flora Probiotic Advanced Immunity 10 Billion is a dietary supplement by Renew Life with 4 active ingredients. Its ingredients are commonly taken for source of b vitamins, diarrhea (certain types), cold and flu support.Based on those ingredients, 256 medications have a known interaction with it, the most serious rated major. The ingredients most likely to interact are Saccharomyces cerevisiae fermentate, Larch Arabinogalactan, Saccharomyces boulardii. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

Jump to a section

Check Your Meds Against Ultimate Flora Probiotic Advanced Immunity 10 Billion by Renew Life

Ask about any prescription or over-the-counter medication and we check it for interactions with Ultimate Flora Probiotic Advanced Immunity 10 Billion by Renew Life — and tell you which ingredient is responsible.

Pharmacist-reviewed data Checks every ingredient Answer in seconds
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HelloPharmacist Scorecard of Ultimate Flora Probiotic Advanced Immunity 10 Billion by Renew Life

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Sep 24, 2026

What’s inside

Low disclosure
Ingredient Transparency · database check
Low

Most active ingredients don't disclose an individual amount — you can't tell how much of each you're getting.

Why this rating?
  • The label discloses an exact amount for 0 of its 4 active ingredients.
  • “Advanced Immunity Blend” is a proprietary blend — the label gives one combined amount (1,350 mg) without saying how much of each component you get.

This product contains four active ingredients. Three of them are probiotics — beneficial live yeast and bacteria — along with a prebiotic fiber.

Saccharomyces cerevisiae fermentate (brewer's yeast) and Saccharomyces boulardii are live yeasts that support digestive and immune health. Larch arabinogalactan is a soluble fiber that feeds beneficial gut bacteria.

The fourth ingredient, Total Probiotic Cultures, is a blend of additional probiotic strains listed in the product name as providing 10 billion colony-forming units (CFU). The capsule itself is made from vegetable material.

Does it work?

Moderate evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Moderate

Some clinical evidence supports this product's ingredients for its stated purpose, but it isn't conclusive.

Why this rating?
  • The label markets this product for: Advanced immunity and gut health support.
  • We looked for evidence on: Antibiotic-associated diarrhea, Clostridioides difficile infection, Common cold, Diarrhea, Influenza, Intestinal parasite infection — and 4 related terms.
  • The strongest evidence on file: Saccharomyces Boulardii is rated "Possibly Effective" for Antibiotic-associated diarrhea (Natural Medicines).
  • Also on file: Saccharomyces Boulardii is rated "Possibly Effective" for Rotaviral diarrhea, Travelers' diarrhea, Clostridioides difficile infection.
  • Also on file: Brewer's Yeast is rated "Possibly Effective" for Irritable bowel syndrome (IBS).

Evidence supports brewer's yeast for irritable bowel syndrome (IBS) — it's rated possibly effective — but evidence is insufficient or missing for its use in clostridioides difficile infection, influenza, high cholesterol, or hay fever. Saccharomyces boulardii is possibly effective for rotaviral diarrhea (diarrhea caused by rotavirus), travelers' diarrhea, antibiotic-associated diarrhea, necrotizing enterocolitis (a serious intestinal condition in newborns), clostridioides difficile infection, and Helicobacter pylori infection.

For larch arabinogalactan, evidence is insufficient for common cold or high cholesterol. We hold no effectiveness data for Total Probiotic Cultures.

The evidence, ingredient by ingredient Brewer's Yeast Saccharomyces Boulardii Larch Arabinogalactan

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 3 of the 3 matched ingredients.
  • Pregnancy & breastfeeding safety ratings cover 3 of 3.
  • General safety write-ups exist for 3 of 3.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Brewer's yeast is generally well tolerated in food amounts, though it can cause gas. Rare but serious concerns include fungemia (yeast in the bloodstream) and anaphylaxis in sensitive people.

The most common side effects are flatulence and migraine-like headaches in some individuals. Saccharomyces boulardii is generally safe for healthy adults but should be avoided if you're critically ill or have a weakened immune system — it too can rarely cause fungemia, especially in hospitalized patients with catheters or on broad-spectrum antibiotics.

Mild gastrointestinal complaints like cramping, flatulence, nausea, and vomiting occur rarely. Larch arabinogalactan is generally well tolerated as a fiber, though some people experience bloating and gas.

High-quality long-term safety data are limited. For pregnancy and breastfeeding, concentrated supplement doses have not been well studied — food amounts are likely fine, but you should check with your doctor or pharmacist before taking this product.

Side effects, ingredient by ingredient Brewer's Yeast Saccharomyces Boulardii Larch Arabinogalactan

Meds to double-check

Major interaction found
Known Interaction Concern · database check
Major identified

At least one ingredient has a documented Major-severity interaction. Check your medications for a personalized result.

Why this rating?
  • 3 of the 3 matched ingredients can interact with medications — Saccharomyces Boulardii, Brewer's Yeast, Larch Arabinogalactan.
  • The most serious interaction on file is rated Major.
  • Some involve high-stakes drug classes: immunosuppressants / transplant drugs; diabetes medications; lithium.
  • For scale: 256 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before you take this product, double-check with your doctor or pharmacist if you're on any of these: MAOIs (Major severity — serious blood pressure risk), blood sugar medications or lithium (both Moderate), antifungals, or immunosuppressants (Moderate). These are the medication types most likely to interact with the live yeasts and larch arabinogalactan in this formula.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFormula with limited ingredient disclosure with some supporting evidence for its stated purpose. Major medication interactions have been identified, and safety information is well characterized.

This probiotic supplement may help with certain types of diarrhea and possibly IBS if brewer's yeast's effects apply to you — but it's not right for everyone. If you take MAOIs for depression, blood sugar medications, lithium, antifungals, or immunosuppressants after a transplant, talk with your doctor or pharmacist before starting.

People who are critically ill or have weakened immune systems should avoid it. Use the interaction checker below with your complete medication list.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 3 of 4 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Feb 25, 2021.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Ultimate Flora Probiotic Advanced Immunity 10 Billion, straight from the product label.

Brand Renew Life
Barcode (UPC) 631257158208
Net contents 30 Vegetable Capsule(s)
Market status On market
Date entered into DSLD Feb 25, 2021
DSLD ID 243607
Product type Other Combinations
Supplement form Capsule
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years), Gluten Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Ultimate Flora Probiotic Advanced Immunity 10 Billion by Renew Life, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
2 Capsule(s)
Maximum serving Sizes:
2 Capsule(s)
Servings per container
15
UPC/BARCODE
631257158208
IngredientAmount% DV
Advanced Immunity Blend1350 mg--
Saccharomyces cerevisiae fermentate0 NP--
Saccharomyces boulardii0 NP--
Larch Arabinogalactan0 NP--
Total Probiotic Cultures0 NP--

Other ingredients: Vegetable Capsule

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Formula

10 billion live cultures per serving Saccharomyces boulardii + Epicor

Special care probiotic for advanced immune support Our Ultimate Flora Special Care Probiotics target your body’s unique needs so you always feel your best. Ultimate Flora Advanced Immunity Probiotic blends the clinically studied probiotic Saccharomyces boulardii with Epicor to provide you with powerful immune protection especially during peak times or when traveling. ResistAid is an effective, natural prebiotic that helps enhance the immune-stimulating probiotics in your gut.

Powerful & Effective Did you know there are 100 trillion bacteria inside your digestive tract? To keep that complex system thriving, our high-potency formulas work hard to provide more of the good-for-you bacteria in your gut. Backed by Science Ultimate Flora Probiotics are made with scientifically studied strains to support your digestive and immune health for better peace of mind. Targeted Delivery Our special Saccharomyces boulardii strain survives stomach acid to help ensure more friendly probiotics reach your intestinal tract.

FDA Statement of Identity

Probiotic Supplement

Suggested/Recommended/Usage/Directions

Directions: Take two capsules daily with a light meal.

Precautions

May contain traces of dairy from fermentation ingredients.

Keep out of reach of children.

Consult your healthcare professional before using this or any product if you are pregnant, nursing, or under medical supervision.

Tamper Evident: Do not use if safety seal under cap is broken or missing.

Tamper Evident: Do not use if safety seal on bottle is broken or missing.

Storage

Store in a dry place at 77 degrees F (25 degrees C) or below.

Formulation

Quality and purity guaranteed.

Manufactured in USA in a GMP facility.

Good for your gut! Your gut is your engine, your digestive core. Keep it running smoothly with Ultimate Flora Probiotics. Our unique formulas promote digestive and immune balance so you feel better, lighter, and more energized.

Powerful Immune & Digestive Support Enhances Seasonal Defenses

Gluten free Soy free No artificial ingredients

Brand IP Statement(s)

EpiCor is a registered trademark of Embria Health Sciences, LLC. ResistAid is a registered trademark of Lonza.

General Statements

New look, same formula.

65413B

Digestive wellness, naturally At Renew Life, we believe a healthy gut is a happy gut. For nearly two decades, we have pioneered superior-quality digestive care supplements to help people achieve optimal health from the inside out.

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Ultimate Flora Probiotic Advanced Immunity 10 Billion by Renew Life label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Ultimate Flora Probiotic Advanced Immunity 10 Billion label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Ultimate Flora Probiotic Advanced Immunity 10 Billion by Renew Life

These are the 4 active ingredients this product is made of. Select any to open its full monograph.

Serving size2 Capsule(s) Dosage formCapsule Servings per container15 Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

Advanced Immunity Blend

1350 mg per serving

Total Probiotic Cultures

0 NP per serving

Other (inactive) ingredients: Vegetable Capsule. These complete the product’s ingredient list but are not active constituents.

Interaction report

Ultimate Flora Probiotic Advanced Immunity 10 Billion by Renew Life Drug Interactions

Want to check YOUR meds against Ultimate Flora Probiotic Advanced Immunity 10 Billion?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
256Drugs
9 Major 207 Moderate 40 Minor

Ingredients driving the most interactions

Saccharomyces cerevisiae fermentate 136
Larch Arabinogalactan 121
Saccharomyces boulardii 40

Individual Drug Interactions

The ingredients in Ultimate Flora Probiotic Advanced Immunity 10 Billion interact with 256 drugs. Click any drug to see the details.

3 of the 4 ingredients in Ultimate Flora Probiotic Advanced Immunity 10 Billion interact with drugs. Each result below shows which ingredient is responsible. Saccharomyces cerevisiae fermentate Larch Arabinogalactan Saccharomyces boulardii

Each ingredient & the kinds of drugs it affects

For each ingredient in Ultimate Flora Probiotic Advanced Immunity 10 Billion with known interactions, here are the types of medications they can affect. Open any type for the detail — or search your exact drug in the checker above.

Saccharomyces cerevisiae fermentate4 drug types · 136 drugs

Monoamine Oxidase Inhibitors (Maois)

Theoretically, taking brewer's yeast with MAOIs might increase the risk of hypertension.
Brewer's yeast contains tyramine. Taking brewer's yeast with MAOIs might increase the risk for hypertensive crisis.

Likelihood Likely Evidence D
Antidiabetes Drugs

Taking brewer's yeast with antidiabetes drugs might increase the risk of hypoglycemia.
Clinical research shows that taking chromium-containing brewer's yeast can decrease levels of blood glucose in diabetic patients being treated with antidiabetes drugs.

Likelihood Possible Evidence B
Lithium

Theoretically, taking brewer's yeast with lithium might cause additive effects and side effects.
Some brewer's yeast products contains lithium.

Likelihood Possible Evidence D
Antifungals

Theoretically, taking antifungals with some brewer's yeast products might decrease the effectiveness of brewer's yeast.
Some brewer's yeast products contain live yeast. Therefore, simultaneously taking antifungals might kill a significant number of the organisms.

Likelihood Possible Evidence D
Saccharomyces cerevisiae fermentate full monograph & interactions

Larch Arabinogalactan1 drug type · 121 drugs

Immunosuppressants

Theoretically, larch arabinogalactan might interfere with immunosuppression therapy due to immunostimulant effects. Immunosuppressant drugs include azathioprine (Imuran), basiliximab (Simulect), cyclosporine (Neoral, Sandimmune), daclizumab (Zenapax), muromonab-CD3 (OKT3, Orthoclone OKT3), mycophenolate (CellCept), tacrolimus (FK506, Prograf), sirolimus (Rapamune), prednisone (Deltasone, Orasone), corticosteroids (glucocorticoids), and other drugs.

Likelihood Possible Evidence D
Larch Arabinogalactan full monograph & interactions

Saccharomyces boulardii1 drug type · 40 drugs

Antifungals

Theoretically, taking antifungals with Saccharomyces boulardii might decrease the effectiveness of Saccharomyces boulardii.
S. boulardii is a live yeast. Therefore, simultaneously taking antifungals might kill a significant number of the organisms.

Likelihood Possible Evidence D
Saccharomyces boulardii full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Ultimate Flora Probiotic Advanced Immunity 10 Billion, from the product label.

Renew Life

Name
Renew Life Formulas
City
Palm Harbor
State
FL
ZipCode
34683
Phone Number
1-800-830-1800
Web Address
www.renewlife.com
Pharmacist Counseling Corner

Ultimate Flora Probiotic Advanced Immunity 10 Billion by Renew Life: Common Questions

Does Ultimate Flora Probiotic Advanced Immunity 10 Billion by Renew Life interact with any medications?
Yes. Based on its ingredients, Ultimate Flora Probiotic Advanced Immunity 10 Billion has a known interaction with 256 medications, including 9 rated major. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Ultimate Flora Probiotic Advanced Immunity 10 Billion contains 4 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Can I take this if I'm on antibiotics?
The probiotics here are actually meant to help restore healthy bacteria after antibiotics disrupt your gut — Saccharomyces boulardii is possibly effective for antibiotic-associated diarrhea. But if you're taking antifungal medications at the same time, the antifungals could kill the live yeasts in this product and reduce its effectiveness. Ask your doctor or pharmacist to time them properly or choose a different option.
Will this cause gas or bloating?
Yes, it can. Flatulence is the most common side effect reported with brewer's yeast, and larch arabinogalactan — which is a fiber — can cause bloating and gas in some people. These tend to be mild and often settle down, but if you have a sensitive gut, start with a lower dose or talk to your pharmacist.
Is it safe during pregnancy?
The safety of concentrated supplement doses during pregnancy hasn't been well studied. Food amounts of these ingredients are likely fine, but you should check with your doctor before taking this product while pregnant or breastfeeding to get personalized advice.
What does the 10 billion in the name mean?
That's the total number of live probiotic cells — called colony-forming units or CFU — in each dose. It represents the strength of the beneficial bacteria and yeast in the capsule.
Can I take this if I have a weak immune system?
No, you should avoid it. Saccharomyces boulardii can rarely cause a serious bloodstream infection (fungemia) in people who are critically ill or immunocompromised, especially if they're in the hospital with central catheters. Talk to your doctor about safer options if your immune system is weakened.
What does larch arabinogalactan do in here?
It's a soluble fiber that acts as a prebiotic — it feeds the beneficial bacteria and yeast in the formula so they can thrive in your gut. It's generally well tolerated, though it can cause bloating or gas like other high-fiber foods.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Ultimate Flora Probiotic Advanced Immunity 10 Billion is safe with your meds?

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Ultimate Flora Probiotic Advanced Immunity 10 Billion label
Go deeper

The Full Monographs Behind Ultimate Flora Probiotic Advanced Immunity 10 Billion’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Brewer's Yeast

Interacts with 136 drugs

Brewer's yeast is a nutrient-rich fungus that provides B vitamins, protein, and minerals, and a related yeast product (S. boulardii) is used for some types of diarrhea. Most other health cla...

Read the full Brewer's Yeast monograph → Herb & supplement monograph

Saccharomyces Boulardii

Interacts with 40 drugs

Saccharomyces boulardii is a beneficial yeast used as a probiotic, with the strongest evidence for preventing and treating certain types of diarrhea, including antibiotic-associated diarrhea...

Read the full Saccharomyces Boulardii monograph → Herb & supplement monograph

Larch Arabinogalactan

Interacts with 121 drugs

Larch arabinogalactan is a soluble fiber from larch trees that is mainly used as a prebiotic and for immune support. Early research is interesting but limited, and most claims are not yet fi...

Read the full Larch Arabinogalactan monograph →
Sources

Sources & How We Checked

Ultimate Flora Probiotic Advanced Immunity 10 Billion's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 40 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Brewer's Yeast 6 references
  1. Blumenthal M, ed. The Complete German Commission E Monographs: Therapeutic Guide to Herbal Medicines. Trans. S. Klein. Boston, MA: American Botanical Council, 1998.
  2. Lewis SJ, Freedman AR. Review article: the use of biotherapeutic agents in the prevention and treatment of gastrointestinal disease. Aliment Pharmacol Ther 1998;12:807-22. PubMed
  3. Bahijiri, S. M., Mira, S. A., Mufti, A. M., and Ajabnoor, M. A. The effects of inorganic chromium and brewer's yeast supplementation on glucose tolerance, serum lipids and drug dosage in individuals with type 2 diabetes. Saudi.Med.J. 2000;21(9):831-837. DOI
  4. Schrauzer, G. N. and de, Vroey E. Effects of nutritional lithium supplementation on mood. A placebo-controlled study with former drug users. Biol.Trace Elem.Res. 1994;40(1):89-101. PubMed
  5. Gayathri R, Aruna T, Malar S, Shilpa B, Dhanasekar KR. Efficacy of Saccharomyces cerevisiae CNCM I-3856 as an add-on therapy for irritable bowel syndrome. Int J Colorectal Dis. 2020;35(1):139-145. PubMed
  6. Mourey F, Decherf A, Jeanne JF, et al. Saccharomyces cerevisiae I-3856 in irritable bowel syndrome with predominant constipation. World J Gastroenterol 2022;28(22):2509-2522.

See these in context on the Brewer's Yeast monograph →

Saccharomyces Boulardii 26 references
  1. Niault M, Thomas F, Prost J, et al. Fungemia due to Saccharomyces species in a patient treated with enteral Saccharomyces boulardii. Clin Infect Dis 1999;28:930.
  2. Pletinex M, Legein J, Vandenplas Y. Fungemia with Saccharomyces boulardii in a 1-year-old girl with protracted diarrhea. J Pediatr Gastroenterol Nutr 1995;21:113-5. DOI
  3. Fredenucci I, Chomarat M, Boucaud C, et al. Saccharomyces boulardii fungemia in a patient receiving ultra-levure therapy. Clin Infect Dis 1998;27:222-3.
  4. Elmer GW, McFarland LV, Surawicz CM, et al. Behaviour of Saccharomyces boulardii in recurrent Clostridium difficile disease patients. Aliment Pharmacol Ther 1999;13:1663-8.
  5. Lewis SJ, Freedman AR. Review article: the use of biotherapeutic agents in the prevention and treatment of gastrointestinal disease. Aliment Pharmacol Ther 1998;12:807-22. PubMed
  6. Cesaro S, Chinello P, Rossi L, Zanesco L. Saccharomyces cerevisiae fungemia in a neutropenic patient treated with Saccharomyces boulardii. Support Care Cancer 2000;8:504-5. PubMed
  7. Hennequin C, Thierry A, Richard GF, et al. Microsatellite typing as a new tool for identification of Saccharomyces cerevisiae strains. J Clin Microbiol 2001;39:551-9.
  8. Plein K, Hotz J. Therapeutic effects of Saccharomyces boulardii on mild residual symptoms in a stable phase of Crohn's disease with special respect to chronic diarrhea - a pilot study. Z Gastroenterol 1993;31:129-34.
  9. Borriello SP, Hammes WP, Holzapfel W, et al. Safety of probiotics that contain lactobacilli or bifidobacteria. Clin Infect Dis 2003;36:775-80. PubMed
  10. Marteau P, Seksik P. Tolerance of probiotics and prebiotics. J Clin Gastroenterol 2004;38:S67-9. PubMed
  11. Munoz P, Bouza E, Cuenca-Estrella M, et al. Saccharomyces cerevisiae fungemia: an emerging infectious disease. Clin Infect Dis 2005;40:1625-34. PubMed
  12. Lherm, T., Monet, C., Nougiere, B., Soulier, M., Larbi, D., Le Gall, C., Caen, D., and Malbrunot, C. Seven cases of fungemia with Saccharomyces boulardii in critically ill patients. Intensive Care Med 2002;28(6):797-801. PubMed
  13. Riquelme, A. J., Calvo, M. A., Guzman, A. M., Depix, M. S., Garcia, P., Perez, C., Arrese, M., and Labarca, J. A. Saccharomyces cerevisiae fungemia after Saccharomyces boulardii treatment in immunocompromised patients. J Clin.Gastroenterol. 2003;36(1):41- PubMed
  14. Cherifi, S., Robberecht, J., and Miendje, Y. Saccharomyces cerevisiae fungemia in an elderly patient with Clostridium difficile colitis. Acta Clin Belg. 2004;59(4):223-224. PubMed
  15. Ellouze O, Berthoud V, Mervant M, Parthiot JP, Girard C. Septic shock due to Sacccaromyces boulardii. Med Mal Infect. 2016;46(2):104-105.
  16. Appel-da-Silva MC, Narvaez GA, Perez LRR, Drehmer L, Lewgoy J. Saccharomyces cerevisiae var. boulardii fungemia following probiotic treatment. Med Mycol Case Rep. 2017;18:15-7. PubMed
  17. Atici S, Soysal A, Karadeniz Cerit K, et al. Catheter-related Saccharomyces cerevisiae Fungemia Following Saccharomyces boulardii Probiotic Treatment: In a child in intensive care unit and review of the literature. Med Mycol Case Rep. 2017;15:33-35. PubMed
  18. Martin IW, Tonner R, Trivedi J, et al. Saccharomyces boulardii probiotic-associated fungemia: questioning the safety of this preventive probiotic's use. Diagn Microbiol Infect Dis. 2017;87(3):286-8. PubMed
  19. Romanio MR, Coraine LA, Maielo VP, Abramczyc ML, Souza RL, Oliveira NF. Saccharomyces cerevisiae fungemia in a pediatric patient after treatment with probiotics. Rev Paul Pediatr 2017;35(3):361-4.
  20. Roy U, Jessani LG, Rudramurthy SM, et al. Seven cases of Saccharomyces fungaemia related to use of probiotics. Mycoses 2017;60(6):375-380.
  21. Romanio MR, Coraine LA, Maielo VP, Abramczyc ML, Souza RL, Oliveira NF. Saccharomyces cerevisiae fungemia in a pediatric patient after treatment with probiotics. Rev Paul Pediatr. 2017 Jul-Sep;35(3):361-364. doi: 10.1590/1984-0462/;2017;35;3;00014.
  22. Flatley EA, Wilde AM, Nailor MD. Saccharomyces boulardii for the prevention of hospital onset Clostridium difficile infection. J Gastrointestin Liver Dis. 2015;24(1):21-4. PubMed
  23. Ventoulis I, Sarmourli T, Amoiridou P, et al. Bloodstream infection by Saccharomyces cerevisiae in two COVID-19 patients after receiving supplementation of Saccharomyces in the ICU. J Fungi (Basel). 2020;6(3):98. PubMed
  24. Wombwell E, Bransteitter B, Gillen LR. Incidence of Saccharomyces cerevisiae fungemia in hospitalised patients administered Saccharomyces boulardii probiotic. Mycoses 2021;64(12):1521-1526.
  25. Rannikko J, Holmberg V, Karppelin M, et al. Fungemia and Other Fungal Infections Associated with Use of Saccharomyces boulardii Probiotic Supplements. Emerg Infect Dis 2021;27(8):2090-6.
  26. Awoyemi A, Mayerhofer C, Felix AS, et al. Rifaximin or Saccharomyces boulardii in heart failure with reduced ejection fraction: Results from the randomized GutHeart trial. EBioMedicine 2021;70:103511. PubMed

See these in context on the Saccharomyces Boulardii monograph →

Larch Arabinogalactan 8 references
  1. D'Adamo P. Larch arabinogalactan. J Naturopath Med 1996;6:33-7.
  2. Kelly GS. Larch arabinogalactan: Clinical relevance of a novel immune-enhancing polysaccharide. Alt Med Rev 1999;4:96-103.
  3. Marett R, Slavin JL. No long-term benefits of supplementation with arabinogalactan on serum lipids and glucose. J Am Diet Assoc 2004;104:636-9.
  4. Robinson RR, Feirtag J, Slavin JL. Effects of dietary arabinogalactan on gastrointestinal and blood parameters in healthy human subjects. J Am Coll Nutr 2001;20:279-85. PubMed
  5. Udani JK, Singh BB, Barrett ML, Singh VJ. Proprietary arabinogalactan extract increases antibody response to the pneumonia vaccine: a randomized, double-blind, placebo-controlled, pilot study in healthy volunteers. Nutr J 2010;9:32. PubMed
  6. Grube B, Stier H, Riede L, Gruenwald J. Tolerability of a proprietary larch arabinogalactan extract: a randomized, double-blind, placebo-controlled clinical trial in healthy subjects. Food Nutr Sci 2012;3:1533-8. DOI
  7. Dion C, Chappuis E, Ripoll C. Does larch arabinogalactan enhance immune function? A review of mechanistic and clinical trials. Nutr Metab (Lond) 2016;13:28. PubMed
  8. Riede L, Grube B, Gruenwald J. Larch arabinogalactan effects on reducing incidence of upper respiratory tract infections. Curr Med Res Opin 2013;29(3):251-8.

See these in context on the Larch Arabinogalactan monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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