Ultimate Selenium Concentrate Ingredients & Drug Interactions
What is this page for?
First and foremost: checking Ultimate Selenium Concentrate against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.
Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy
Ultimate Selenium Concentrate is a dietary supplement by Complete H2O Minerals with 1 active ingredient. Its ingredients are commonly taken for thyroid health support, antioxidant support, immune support.Based on those ingredients, 321 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Selenium. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.
Check Your Meds Against Ultimate Selenium Concentrate by Complete H2O Minerals
Ask about any prescription or over-the-counter medication and we check it for interactions with Ultimate Selenium Concentrate by Complete H2O Minerals — and tell you which ingredient is responsible.
AI summaries are generated from our interaction database for education only — always confirm with your pharmacist. How we use AI
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HelloPharmacist Scorecard of Ultimate Selenium Concentrate by Complete H2O Minerals
Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.
What’s inside
Full disclosure
Ultimate Selenium Concentrate contains one active ingredient: selenium, a trace mineral your body needs for thyroid function, immune health, and antioxidant protection. The product delivers it in liquid form.
It also contains purified water and selenium nitrate as inactive ingredients.
Does it work?
Couldn't assess
Selenium is likely effective for treating selenium deficiency. For other uses — including Kashin-Beck disease (a joint condition), pre-eclampsia (high blood pressure in pregnancy), autoimmune thyroiditis (an immune thyroid condition), and dyslipidemia (abnormal blood fat levels) — the evidence is either possibly effective or possibly ineffective.
The data we hold rates dyslipidemia as possibly ineffective.
How safe is it?
Well-documented data
Selenium is generally well tolerated when you stay within the safe upper limit of 400 mcg daily. The most common side effects at normal doses are gastric discomfort, headache, and rash.
Taking too much can cause hair loss, skin problems, fatigue, nail changes, nausea, vomiting, and weight loss. Rare but serious cases of excessive intake have led to multi-organ failure.
Chronic exposure to very high doses may raise the risk of amyotrophic lateral sclerosis (ALS) and increase the chance of certain skin cancers. For pregnancy, the safety data shows mixed information — talk with your doctor or pharmacist about whether it's right for you.
Lactation data suggests it's possibly safe, but confirm with your healthcare provider.
Meds to double-check
Moderate interaction found
Before taking this product, check with your doctor or pharmacist if you take blood thinners or antiplatelet drugs (moderate risk of increased bleeding), barbiturates or sedatives (moderate risk of prolonged drowsiness), warfarin / Coumadin (moderate risk of interference), immunosuppressant medications (moderate risk of reduced effectiveness), birth control pills (minor — may raise selenium levels), or niacin supplements (minor — may reduce cholesterol benefits).
The bottom line
Scorecard at a glanceFully disclosed formula with no assessable stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.
This product is worth considering if you have a selenium deficiency or are interested in thyroid support, but only at normal recommended doses — excess selenium is toxic. If you take blood thinners, barbiturates, warfarin, immunosuppressants, birth control, or niacin, check with your doctor or pharmacist before starting.
Talk it over with your own healthcare provider to make sure it fits your health picture.
Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI
Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Jul 27, 2021.
This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed
General information
Key facts about Ultimate Selenium Concentrate, straight from the product label.
| Brand | Complete H2O Minerals |
|---|---|
| Barcode (UPC) | 852670006246 |
| Net contents | 2 Oz(s); 60 mL |
| Market status | On market |
| Date entered into DSLD | Jul 27, 2021 |
| DSLD ID | 252081 |
| Product type | Mineral |
| Supplement form | Liquid |
| Dietary claims / uses | Nutrient, All Other, Structure/Function |
| Intended target group(s) | Adult (18 - 50 Years), Children (All) |
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.
Supplement Facts
The label details for Ultimate Selenium Concentrate by Complete H2O Minerals, sourced from the NIH Dietary Supplement Label Database.
Supplement Facts
| Ingredient | Amount | % DV |
|---|---|---|
| Selenium | 750 mcg | 375% |
Other ingredients: purified Water, Selenium Nitrate
Tap any ingredient to jump to its full detail below.
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Formula
Selenium Selenium is one of the most efficient antioxidants. It prevents cellular and subcellular lipids and fats from being peroxided, or becoming rancid. Selenium is also instrumental in supporting both a healthy immune system and cardiovascular system.
Suggested/Recommended/Usage/Directions
Mixing Instructions: Mix with 8 to 10 ounces of juice or water.
For best results, store in a cool, dark place and use within six months.
Recommended Dosage: Adults: 1 mL 750 mcg Children: 0.5 mL 375 mcg or as recommended by a health care professional.
Formulation
In processing, FDA & GMP guidelines are observed and strictly followed.
Complete H2O Minerals contain no fillers or artificial ingredients.
FDA Disclaimer Statement
Disclaimer: This product is not intended to diagnose, treat, prevent or cure any disease.
General Statements
Quality products for a quality life!
FDA Statement of Identity
Dietary Supplement
Storage
For best results, store in a cool, dark place and use within six months.
Precautions
Note: Do not use if tamper seal is broken or missing.
Is this label outdated? Report a formula or label change and our pharmacy team will review it.
Ultimate Selenium Concentrate by Complete H2O Minerals label
The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.
Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.
View the full label (PDF)The Ingredients in Ultimate Selenium Concentrate by Complete H2O Minerals
This is the 1 active ingredient this product is made of. Select it to open its full monograph.
Serving size1 mL Dosage formLiquid Servings per container60 Amounts shown are per serving.
Selenium
Interacts with321 drugs
Selenium is an essential trace mineral your body needs in small amounts for thyroid function, antioxidant defense, and immune health. Most people who...
Selenium monograph & interactionsOther (inactive) ingredients: Purified Water, Selenium Nitrate. These complete the product’s ingredient list but are not active constituents.
Ultimate Selenium Concentrate by Complete H2O Minerals Drug Interactions
HelloPharmacist Interaction Report
Ultimate Selenium Concentrate by Complete H2O Minerals can interact with several medication types.
Through its selenium content, the most serious documented interaction is with blood thinners (anticoagulants) and antiplatelet drugs — selenium may increase bleeding risk by thinning the blood further.
Read the full breakdown — every affected drug type, severity by severity
Selenium may also reduce how well immunosuppressant medications work by stimulating your immune system. It could prolong the sedating effects of barbiturates (sedative drugs), and it might interfere with warfarin (Coumadin) activity, possibly by displacing it from protein binding sites or slowing its breakdown in the liver.
Birth control pills might raise your selenium levels, though we're not sure how much that matters clinically. Selenium may also reduce niacin's beneficial effects on HDL cholesterol.
Altogether, these interactions span 321 individual medications. Before you start this product, check your exact medications with the search tool on this page or run them by your doctor or pharmacist.
Check your own medications below · Editorial policy · How we use AI
Want to check YOUR meds against Ultimate Selenium Concentrate?
Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.
Go to the checkerIngredients driving the most interactions
Individual Drug Interactions
The ingredients in Ultimate Selenium Concentrate interact with 321 drugs. Click any drug to see the details.
1 of the 1 ingredient in Ultimate Selenium Concentrate interact with drugs. Each result below shows which ingredient is responsible. Selenium
Betamethasone DipropionateSernivo
How Betamethasone Dipropionate interacts with Ultimate Selenium Concentrate — through 1 ingredient. Tap an ingredient for the detail:
SeleniumImmunosuppressants Moderate
Interaction Summary
Theoretically, selenium supplementation may reduce the effectiveness of immunosuppressant therapy.
Read the full Selenium + Betamethasone Dipropionate interactionBetamethasone Dipropionate, CalcipotrieneEnstilar, Wynzora
How Betamethasone Dipropionate, Calcipotriene interacts with Ultimate Selenium Concentrate — through 1 ingredient. Tap an ingredient for the detail:
SeleniumImmunosuppressants Moderate
Interaction Summary
Theoretically, selenium supplementation may reduce the effectiveness of immunosuppressant therapy.
Read the full Selenium + Betamethasone Dipropionate, Calcipotriene interactionBetamethasone ValerateLuxiq
How Betamethasone Valerate interacts with Ultimate Selenium Concentrate — through 1 ingredient. Tap an ingredient for the detail:
SeleniumImmunosuppressants Moderate
Interaction Summary
Theoretically, selenium supplementation may reduce the effectiveness of immunosuppressant therapy.
Read the full Selenium + Betamethasone Valerate interactionBetrixabanBevyxxa
How Betrixaban interacts with Ultimate Selenium Concentrate — through 1 ingredient. Tap an ingredient for the detail:
SeleniumAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Selenium may have antiplatelet effects and may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
Read the full Selenium + Betrixaban interactionBimekizumab-bkzxBimzelx
How Bimekizumab-bkzx interacts with Ultimate Selenium Concentrate — through 1 ingredient. Tap an ingredient for the detail:
SeleniumImmunosuppressants Moderate
Interaction Summary
Theoretically, selenium supplementation may reduce the effectiveness of immunosuppressant therapy.
Read the full Selenium + Bimekizumab-bkzx interactionBivalirudinAngiomax, Angiomax Rtu, Angiox
How Bivalirudin interacts with Ultimate Selenium Concentrate — through 1 ingredient. Tap an ingredient for the detail:
SeleniumAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Selenium may have antiplatelet effects and may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
Read the full Selenium + Bivalirudin interactionBromfenac SodiumBromsite, Prolensa
How Bromfenac Sodium interacts with Ultimate Selenium Concentrate — through 1 ingredient. Tap an ingredient for the detail:
SeleniumAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Selenium may have antiplatelet effects and may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
Read the full Selenium + Bromfenac Sodium interactionButabarbital SodiumButisol Sodium, Sarisol #2
How Butabarbital Sodium interacts with Ultimate Selenium Concentrate — through 1 ingredient. Tap an ingredient for the detail:
SeleniumBarbiturates Moderate
Interaction Summary
Theoretically, selenium might prolong the sedating effects of barbiturates.
Read the full Selenium + Butabarbital Sodium interactionButabarbital, Hyoscyamine, PhenazopyridinePyridium Plus
How Butabarbital, Hyoscyamine, Phenazopyridine interacts with Ultimate Selenium Concentrate — through 1 ingredient. Tap an ingredient for the detail:
SeleniumBarbiturates Moderate
Interaction Summary
Theoretically, selenium might prolong the sedating effects of barbiturates.
Read the full Selenium + Butabarbital, Hyoscyamine, Phenazopyridine interactionButabarbital, Phenobarbital, SecobarbitalS.B.P.
How Butabarbital, Phenobarbital, Secobarbital interacts with Ultimate Selenium Concentrate — through 1 ingredient. Tap an ingredient for the detail:
SeleniumBarbiturates Moderate
Interaction Summary
Theoretically, selenium might prolong the sedating effects of barbiturates.
Read the full Selenium + Butabarbital, Phenobarbital, Secobarbital interactionButalbital, Phenobarbital, SecobarbitalTribarb
How Butalbital, Phenobarbital, Secobarbital interacts with Ultimate Selenium Concentrate — through 1 ingredient. Tap an ingredient for the detail:
SeleniumBarbiturates Moderate
Interaction Summary
Theoretically, selenium might prolong the sedating effects of barbiturates.
Read the full Selenium + Butalbital, Phenobarbital, Secobarbital interactionCabliviCablivi
How Cablivi interacts with Ultimate Selenium Concentrate — through 1 ingredient. Tap an ingredient for the detail:
SeleniumAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Selenium may have antiplatelet effects and may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
Read the full Selenium + Cablivi interactionCamphor, Hyoscyamine, Passif, Phenobarbital, Scopolamine, ValerianNevrotose #3
How Camphor, Hyoscyamine, Passif, Phenobarbital, Scopolamine, Valerian interacts with Ultimate Selenium Concentrate — through 1 ingredient. Tap an ingredient for the detail:
SeleniumBarbiturates Moderate
Interaction Summary
Theoretically, selenium might prolong the sedating effects of barbiturates.
Read the full Selenium + Camphor, Hyoscyamine, Passif, Phenobarbital, Scopolamine, Valerian interactionCangrelorKengreal
How Cangrelor interacts with Ultimate Selenium Concentrate — through 1 ingredient. Tap an ingredient for the detail:
SeleniumAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Selenium may have antiplatelet effects and may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
Read the full Selenium + Cangrelor interactionCiclesonideAlvesco, Omnaris, Zetonna
How Ciclesonide interacts with Ultimate Selenium Concentrate — through 1 ingredient. Tap an ingredient for the detail:
SeleniumImmunosuppressants Moderate
Interaction Summary
Theoretically, selenium supplementation may reduce the effectiveness of immunosuppressant therapy.
Read the full Selenium + Ciclesonide interactionCilostazolPletal
How Cilostazol interacts with Ultimate Selenium Concentrate — through 1 ingredient. Tap an ingredient for the detail:
SeleniumAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Selenium may have antiplatelet effects and may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
Read the full Selenium + Cilostazol interactionCisplatinPlatinol-AQ
How Cisplatin interacts with Ultimate Selenium Concentrate — through 1 ingredient. Tap an ingredient for the detail:
SeleniumImmunosuppressants Moderate
Interaction Summary
Theoretically, selenium supplementation may reduce the effectiveness of immunosuppressant therapy.
Read the full Selenium + Cisplatin interactionCladribineLeustatin, Mavenclad
How Cladribine interacts with Ultimate Selenium Concentrate — through 1 ingredient. Tap an ingredient for the detail:
SeleniumImmunosuppressants Moderate
Interaction Summary
Theoretically, selenium supplementation may reduce the effectiveness of immunosuppressant therapy.
Read the full Selenium + Cladribine interactionClopidogrelPlavix
How Clopidogrel interacts with Ultimate Selenium Concentrate — through 1 ingredient. Tap an ingredient for the detail:
SeleniumAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Selenium may have antiplatelet effects and may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
Read the full Selenium + Clopidogrel interactionCopanlisibAliqopa
How Copanlisib interacts with Ultimate Selenium Concentrate — through 1 ingredient. Tap an ingredient for the detail:
SeleniumImmunosuppressants Moderate
Interaction Summary
Theoretically, selenium supplementation may reduce the effectiveness of immunosuppressant therapy.
Read the full Selenium + Copanlisib interactionCortisone AcetateCortisone Tablets, Cortone
How Cortisone Acetate interacts with Ultimate Selenium Concentrate — through 1 ingredient. Tap an ingredient for the detail:
SeleniumImmunosuppressants Moderate
Interaction Summary
Theoretically, selenium supplementation may reduce the effectiveness of immunosuppressant therapy.
Read the full Selenium + Cortisone Acetate interactionCyclophosphamideCytoxan, Neosar
How Cyclophosphamide interacts with Ultimate Selenium Concentrate — through 1 ingredient. Tap an ingredient for the detail:
SeleniumImmunosuppressants Moderate
Interaction Summary
Theoretically, selenium supplementation may reduce the effectiveness of immunosuppressant therapy.
Read the full Selenium + Cyclophosphamide interactionCyclosporineCequa, Ciclosporine, Gengraf, Neoral, Sandimmune, Verkazia +1 more
How Cyclosporine interacts with Ultimate Selenium Concentrate — through 1 ingredient. Tap an ingredient for the detail:
SeleniumImmunosuppressants Moderate
Interaction Summary
Theoretically, selenium supplementation may reduce the effectiveness of immunosuppressant therapy.
Read the full Selenium + Cyclosporine interactionDaclizumabZenapax, Zinbryta
How Daclizumab interacts with Ultimate Selenium Concentrate — through 1 ingredient. Tap an ingredient for the detail:
SeleniumImmunosuppressants Moderate
Interaction Summary
Theoretically, selenium supplementation may reduce the effectiveness of immunosuppressant therapy.
Read the full Selenium + Daclizumab interactionDalteparinFragmin
How Dalteparin interacts with Ultimate Selenium Concentrate — through 1 ingredient. Tap an ingredient for the detail:
SeleniumAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Selenium may have antiplatelet effects and may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
Read the full Selenium + Dalteparin interactionDanaparoidOrgaran
How Danaparoid interacts with Ultimate Selenium Concentrate — through 1 ingredient. Tap an ingredient for the detail:
SeleniumAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Selenium may have antiplatelet effects and may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
Read the full Selenium + Danaparoid interactionDefibrotide SodiumDefitelio
How Defibrotide Sodium interacts with Ultimate Selenium Concentrate — through 1 ingredient. Tap an ingredient for the detail:
SeleniumAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Selenium may have antiplatelet effects and may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
Read the full Selenium + Defibrotide Sodium interactionDeflazacortEmflaza
How Deflazacort interacts with Ultimate Selenium Concentrate — through 1 ingredient. Tap an ingredient for the detail:
SeleniumImmunosuppressants Moderate
Interaction Summary
Theoretically, selenium supplementation may reduce the effectiveness of immunosuppressant therapy.
Read the full Selenium + Deflazacort interactionDehydrocholic Acid, Homatropine Methylbromide, PhenobarbitalG.B.S.
How Dehydrocholic Acid, Homatropine Methylbromide, Phenobarbital interacts with Ultimate Selenium Concentrate — through 1 ingredient. Tap an ingredient for the detail:
SeleniumBarbiturates Moderate
Interaction Summary
Theoretically, selenium might prolong the sedating effects of barbiturates.
Read the full Selenium + Dehydrocholic Acid, Homatropine Methylbromide, Phenobarbital interactionDenosumabProlia, XGEVA
How Denosumab interacts with Ultimate Selenium Concentrate — through 1 ingredient. Tap an ingredient for the detail:
SeleniumImmunosuppressants Moderate
Interaction Summary
Theoretically, selenium supplementation may reduce the effectiveness of immunosuppressant therapy.
Read the full Selenium + Denosumab interactionEach ingredient & the kinds of drugs it affects
For each ingredient in Ultimate Selenium Concentrate with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.
Selenium
Anticoagulant/Antiplatelet Drugs
Selenium may have antiplatelet effects and may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
Clinical research suggests that taking selenium 10 mcg/kg/day can increase bleeding times by increasing prostacyclin production, which inhibits platelet activity. Other clinical research suggests that taking selenium 75 mcg daily, in combination with ascorbic acid 600 mg, alpha-tocopherol 300 mg, and beta-carotene 27 mg, reduces platelet aggregation.
Barbiturates
Theoretically, selenium might prolong the sedating effects of barbiturates.
Laboratory research suggests that selenium can inhibit the hepatic metabolism of barbiturates. Selenium seems to prolong the sedative effect of pentobarbital in animal models.
Immunosuppressants
Theoretically, selenium supplementation may reduce the effectiveness of immunosuppressant therapy.
In vitro research and preliminary clinical evidence suggests that selenium may stimulate the immune system.
Warfarin (Coumadin)
Theoretically, selenium might interfere with warfarin activity.
Animal research suggests that selenium can increase warfarin activity. Selenium might interact with warfarin by displacing it from albumin binding sites, reducing its metabolism in the liver, or by decreasing production of vitamin K-dependent clotting factors. Selenium can also prolong bleeding times in humans by increasing prostacyclin production, which inhibits platelet activity.
Contraceptive Drugs
Contraceptive drugs might increase levels of selenium, although the clinical significance of this effect is unclear.
Some research suggests that oral contraceptives increase serum selenium levels in women taking oral contraceptives; however, other research shows no change in selenium levels. It is suggested that an increase could be due to increased carrier proteins, indicating a redistribution of selenium rather than a change in total body selenium.
Niacin
Selenium might reduce the beneficial effects of niacin on high-density lipoprotein (HDL) levels.
A combination of niacin and simvastatin (Zocor) effectively raises HDL cholesterol levels in patients with coronary disease and low HDL levels. Clinical research shows that taking a combination of antioxidants (vitamin C, vitamin E, beta-carotene, and selenium) along with niacin and simvastatin (Zocor) attenuates this rise in HDL, specifically the HDL-2 and apolipoprotein A1 fractions, by more than 50% in patients with coronary disease. It is not known whether this adverse effect is due to a single antioxidant such as selenium, or to the combination. It also is not known whether it will occur in other patient populations.
Brand information
Manufacturer and brand details for Ultimate Selenium Concentrate, from the product label.
Complete H2O Minerals
See all Complete H2O Minerals products- Name
- Complete H2O Minerals
- Street Address
- 1167 West 3050 South
- City
- Ogden
- State
- UT
- ZipCode
- 84401
- Phone Number
- 1.877.646.3725
- Web Address
- www.completeh2ominerals.com
Ultimate Selenium Concentrate by Complete H2O Minerals: Common Questions
Does Ultimate Selenium Concentrate by Complete H2O Minerals interact with any medications?
How can one product interact with so many drugs?
Where does this information come from?
What does selenium actually do in my body?
Is this product effective for anything besides selenium deficiency?
What are the side effects if I take too much?
Is it safe to take while pregnant or breastfeeding?
How much selenium is safe to take daily?
Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
Not sure if Ultimate Selenium Concentrate is safe with your meds?
Our pharmacists answer your medication & supplement questions — free.
Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.
The Full Monographs Behind Ultimate Selenium Concentrate’s Ingredients
Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.
Sources & How We Checked
Ultimate Selenium Concentrate's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.
- NIH Dietary Supplement Label Database (DSLD) — The official product label on file for this supplement.
- Natural Medicines (Therapeutic Research Center) — Evidence-graded clinical reference behind the ingredient interaction data.
Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.
The 36 references behind this product’s interaction data
Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.
Selenium 36 references
- Food and Nutrition Board, Institute of Medicine. Dietary Reference Intakes for Vitamin C, Vitamin E, Selenium, and Carotenoids. Washington, DC: National Academy Press, 2000. Available at: http://www.nap.edu/books/0309069351/html/.
- Brown BG, Zhao XQ, Chait A, et al. Simvastatin and niacin, antioxidant vitamins, or the combination for the prevention of coronary disease. N Engl J Med 2001;345:1583-93. DOI
- Trafikowska U, Zachara BA, Wiacek M, et al. Selenium supply and glutathione peroxidase activity in breastfed Polish infants. Acta Paediatr 1996;85:1143-5. PubMed
- Duffield-Lillico AJ, Slate EH, Reid ME, et al. Selenium supplementation and secondary prevention of nonmelanoma skin cancer in a randomized trial. J Natl Cancer Inst 2003;95:1477-81.. PubMed
- Cheung MC, Zhao XQ, Chait A, et al. Antioxidant supplements block the response of HDL to simvastatin-niacin therapy in patients with coronary artery disease and low HDL. Arterioscler Thromb Vasc Biol 2001;21:1320-6. PubMed
- Schiavon R, Freeman GE, Guidi GC, et al. Selenium enhances prostacyclin production by cultured endothelial cells: possible explanation for increased bleeding times in volunteers taking selenium as a dietary supplement. Thromb Res 1984;34:389-96. PubMed
- Davila JC, Edds GT, Osuna O, Simpson CF. Modification of the effects of aflatoxin B1 and warfarin in young pigs given selenium. Am J Vet Res 1983;44:1877-83. DOI
- Heese HD, Lawrence MA, Dempster WS, Pocock F. Reference concentrations of serum selenium and manganese in healthy nulliparas. S Afr Med J 1988;73:163-5.
- Lloyd B, Lloyd RS, Clayton BE. Effect of smoking, alcohol and other factors on the selenium status of a healthy population. J Epidemiol Commun Health 1983;37:213-7. PubMed
- Capel ID, Jenner M, Williams DC, et al. The effect of prolonged oral contraceptive steroid use on erythrocyte glutathione peroxidase activity. J Steroid Biochem 1981;14:729-32. PubMed
- Contempre B, Dumont JE, Ngo B, et al. Effect of selenium supplementation in hypothyroid subjects of an iodine and selenium deficient area: the possible danger of indiscriminate supplementation of iodine-deficient subjects with selenium. J Clin Endocrinol PubMed
- Hofbauer LC, Spitzweg C, Magerstadt RA, Heufelder AE. Selenium-induced thyroid dysfunction. Postgrad Med J 1997;73:103-4. PubMed
- Debski B, Milner JA. Dietary selenium supplementation prolongs pentobarbital induced hypnosis. J Nutr Biochem 2004;15:548-53. PubMed
- Ishikawa M, Sasaki M, Koiwai K, et al. Inhibition of hepatic mixed-function oxidase enzymes in mice by acute and chronic treatment with selenium. J Pharmacobiodyn 1992;15:377-85. PubMed
- Lippmann SM, Klein EA, Goodman PJ, et al. Effect of selenium and vitamin E on risk of prostate cancer and other cancers: the selenium and vitamin E cancer prevention trial (SELECT). JAMA 2009;301:39-51. DOI
- Reid SM, Middleton P, Cossich MC, Crowther CA. Interventions for clinical and subclinical hypothyroidism in pregnancy. Cochrane Database Syst Rev 2010;(7):CD007752. PubMed
- Vinceti, M., Wei, E. T., Malagoli, C., Bergomi, M., and Vivoli, G. Adverse health effects of selenium in humans. Rev.Environ.Health 2001;16(4):233-251. PubMed
- Abrams, C. K., Siram, S. M., Galsim, C., Johnson-Hamilton, H., Munford, F. L., and Mezghebe, H. Selenium deficiency in long-term total parenteral nutrition. Nutr Clin Pract 1992;7(4):175-178. PubMed
- Spiller, H. A. and Pfiefer, E. Two fatal cases of selenium toxicity. Forensic Sci Int 8-24-2007;171(1):67-72. PubMed
- Negro, R., Greco, G., Mangieri, T., Pezzarossa, A., Dazzi, D., and Hassan, H. The influence of selenium supplementation on postpartum thyroid status in pregnant women with thyroid peroxidase autoantibodies. J Clin Endocrinol.Metab 2007;92(4):1263-1268. PubMed
- Alexander, J. Selenium. Novartis.Found.Symp 2007;282:143-149.
- Salonen, J. T., Salonen, R., Seppanen, K., Rinta-Kiikka, S., Kuukka, M., Korpela, H., Alfthan, G., Kantola, M., and Schalch, W. Effects of antioxidant supplementation on platelet function: a randomized pair-matched, placebo-controlled, double-blind trial
- Kupka, R., Mugusi, F., Aboud, S., Msamanga, G. I., Finkelstein, J. L., Spiegelman, D., and Fawzi, W. W. Randomized, double-blind, placebo-controlled trial of selenium supplements among HIV-infected pregnant women in Tanzania: effects on maternal and chil
- Kamble, P., Mohsin, N., Jha, A., Date, A., Upadhaya, A., Mohammad, E., Khalil, M., Pakkyara, A., and Budruddin, M. Selenium intoxication with selenite broth resulting in acute renal failure and severe gastritis. Saudi.J Kidney Dis.Transpl. 2009;20(1):106
- Peretz, A., Neve, J., Desmedt, J., Duchateau, J., Dramaix, M., and Famaey, J. P. Lymphocyte response is enhanced by supplementation of elderly subjects with selenium-enriched yeast. Am.J Clin.Nutr. 1991;53(5):1323-1328. PubMed
- Kumpulainen, J., Salmenpera, L., Siimes, M. A., Koivistoinen, P., and Perheentupa, J. Selenium status of exclusively breast-fed infants as influenced by maternal organic or inorganic selenium supplementation. Am.J Clin.Nutr. 1985;42(5):829-835. PubMed
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