Vegan Vitamin D 800 IU Ingredients & Drug Interactions
by DEVA
What is this page for?
First and foremost: checking Vegan Vitamin D 800 IU against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.
Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy
Vegan Vitamin D 800 IU is a dietary supplement by DEVA with 1 active ingredient. Its ingredients are commonly taken for bone health and osteoporosis, correcting vitamin d deficiency, immune system support.Based on those ingredients, 715 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Vitamin D2. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.
Check Your Meds Against Vegan Vitamin D 800 IU by DEVA
Ask about any prescription or over-the-counter medication and we check it for interactions with Vegan Vitamin D 800 IU by DEVA — and tell you which ingredient is responsible.
AI summaries are generated from our interaction database for education only — always confirm with your pharmacist. How we use AI
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HelloPharmacist Scorecard of Vegan Vitamin D 800 IU by DEVA
Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.
What’s inside
Full disclosure
This product contains one active ingredient: vitamin D2 (ergocalciferol), a form of vitamin D derived from plant sources. It delivers 800 IU per tablet.
The remaining ingredients—cellulose, dicalcium phosphate, croscarmellose sodium, stearic acid, silica, vegetable magnesium stearate, hypromellose, and vegetable glycerin—are inactive binders, fillers, and capsule materials that help hold the tablet together.
Does it work?
Strong evidence
Vitamin D2 at this dose is effective for treating specific vitamin D deficiency conditions: familial hypophosphatemia, osteomalacia (soft bones), renal osteodystrophy (bone disease from kidney problems), rickets (bone disease in children), and hypoparathyroidism (low parathyroid hormone). This 800 IU dose is a maintenance or supplement level; your doctor can tell you whether it's right for your particular condition.
How safe is it?
Well-documented data
Vitamin D is generally well tolerated at recommended doses, but very high doses over long periods can cause toxicity with symptoms like high blood calcium. At recommended amounts, vitamin D is often used during pregnancy and lactation, but only under a doctor's guidance.
The safety data we hold advises checking with your doctor before taking amounts higher than recommended. In rare cases, excessive doses can lead to vitamin D toxicity symptoms including high blood calcium, bone loss in adults, slowed growth in children, eye inflammation, and light sensitivity.
Meds to double-check
Moderate interaction found
Before taking this product, check with us if you're on thiazide diuretics, verapamil, diltiazem, digoxin, atorvastatin, calcipotriene, or any medications metabolized by the liver enzyme CYP3A4. High-dose vitamin D can raise blood calcium and interfere with how these drugs work; the standard recommendation is to stay below 4000 IU daily for adults unless your doctor directs otherwise.
The bottom line
Scorecard at a glanceFully disclosed formula with clinical evidence supporting its stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.
This is a straightforward vitamin D supplement at a modest dose, commonly used for deficiency-related bone conditions. If you're on any heart medications, water pills, cholesterol drugs, or calcium-regulating medications, run them through our checker first.
Pregnant or breastfeeding? Talk with your doctor before starting.
A pharmacist can confirm whether this dose is right for you.
Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI
Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Nov 22, 2022.
This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed
General information
Key facts about Vegan Vitamin D 800 IU, straight from the product label.
| Brand | DEVA |
|---|---|
| Barcode (UPC) | 895634000270 |
| Net contents | 90 Tablet(s) |
| Market status | On market |
| Date entered into DSLD | Nov 22, 2022 |
| DSLD ID | 276383 |
| Product type | Vitamin |
| Supplement form | Tablet Or Pill |
| Dietary claims / uses | Nutrient, All Other |
| Intended target group(s) | Vegan, Vegetarian, Adult (18 - 50 Years), Gluten Free, Sugar Free |
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.
Supplement Facts
The label details for Vegan Vitamin D 800 IU by DEVA, sourced from the NIH Dietary Supplement Label Database.
Supplement Facts
| Ingredient | Amount | % DV |
|---|---|---|
| Vitamin D2 | 60 mcg | 300% |
Other ingredients: Cellulose, Dicalcium Phosphate, Croscarmellose Sodium, Stearic Acid, Silica, Vegetable Magnesium Stearate, Hypromellose, Vegetable Glycerin
Tap any ingredient to jump to its full detail below.
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Formula
Ergocalciferol is the only type of Vitamin D used in this high quality product.
D2 - 20 mcg
Precautions
Keep out of reach of children.
Tamper evident: Do not use if imprinted seal under cap is broken.
Always consult your doctor before taking dietary supplements. It is recommended that individuals who take more than 50 mcg (2,000 IU) per day of vitamin D have their vitamin D levels monitored.
Storage
Store in a cool, dry place.
Formulation
Food sensitivity: Free of yeast, gluten, soy, wheat, sugar, salt, animal products, byproducts or derivatives.
100% Vegan 100% vegetarian, vegan. This product is registered with the vegan society.
This product does not contain animal products, derivatives or byproducts.
General Statements
Tiny tablets
FDA Statement of Identity
Dietary Supplement
Suggested/Recommended/Usage/Directions
Directions: For adults, take one (1) tablet daily with a food, or as directed by a doctor.
Seals/Symbols
Vegan
Is this label outdated? Report a formula or label change and our pharmacy team will review it.
Vegan Vitamin D 800 IU by DEVA label
The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.
Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.
View the full label (PDF)The Ingredients in Vegan Vitamin D 800 IU by DEVA
This is the 1 active ingredient this product is made of. Select it to open its full monograph.
Serving size1 Tablet(s) Dosage formTablet Or Pill Servings per container90 Amounts shown are per serving.
Vitamin D2
Interacts with715 drugs
Vitamin D is a fat-soluble vitamin that helps your body absorb calcium and is important for healthy bones, muscles, and immune function. Many people,...
Vitamin D2 monograph & interactionsOther (inactive) ingredients: Cellulose, Dicalcium Phosphate, Croscarmellose Sodium, Stearic Acid, Silica, Vegetable Magnesium Stearate, Hypromellose, Vegetable Glycerin. These complete the product’s ingredient list but are not active constituents.
Vegan Vitamin D 800 IU by DEVA Drug Interactions
HelloPharmacist Interaction Report
DEVA's Vegan Vitamin D 800 IU contains vitamin D2, which is documented to interact with several medication types.
The most serious concern is with thiazide diuretics (water pills used for high blood pressure), which can theoretically increase the risk of high blood calcium (hypercalcemia) when combined with vitamin D, especially at higher doses.
Read the full breakdown — every affected drug type, severity by severity
Vitamin D also has moderate interactions with heart rhythm medications including verapamil, diltiazem, and digoxin. High-dose vitamin D can raise blood calcium, which may reduce how well these drugs work or increase the risk of dangerous heart rhythms.
Additionally, vitamin D may reduce how much of the cholesterol drug atorvastatin your body absorbs, and it can theoretically increase aluminum absorption in people with kidney problems. Calcipotriene, a vitamin D-like medication used for psoriasis, poses a combined hypercalcemia risk if taken with this supplement.
There's also a minor interaction with a broad group of drugs metabolized by the liver enzyme CYP3A4; vitamin D may reduce their effectiveness, though this is less well established. Altogether, these interactions span 705 individual medications.
Use the medication checker below to see if any of yours are affected.
Check your own medications below · Editorial policy · How we use AI
Want to check YOUR meds against Vegan Vitamin D 800 IU?
Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.
Go to the checkerIngredients driving the most interactions
Individual Drug Interactions
The ingredients in Vegan Vitamin D 800 IU interact with 715 drugs. Click any drug to see the details.
1 of the 1 ingredient in Vegan Vitamin D 800 IU interact with drugs. Each result below shows which ingredient is responsible. Vitamin D2
Alginic Acid, Aluminum HydroxideRafton
How Alginic Acid, Aluminum Hydroxide interacts with Vegan Vitamin D 800 IU — through 1 ingredient. Tap an ingredient for the detail:
Vitamin D2Aluminum Moderate
Interaction Summary
Vitamin D might increase aluminum absorption and toxicity, but this has only been reported in people with renal failure.
Read the full Vitamin D2 + Alginic Acid, Aluminum Hydroxide interactionAluminum Acetate, Benzethonium ChlorideBuro-Sol Otic Solution
How Aluminum Acetate, Benzethonium Chloride interacts with Vegan Vitamin D 800 IU — through 1 ingredient. Tap an ingredient for the detail:
Vitamin D2Aluminum Moderate
Interaction Summary
Vitamin D might increase aluminum absorption and toxicity, but this has only been reported in people with renal failure.
Read the full Vitamin D2 + Aluminum Acetate, Benzethonium Chloride interactionAluminum ChlorideAluminum Chloride, Anhydrol Forte, Driclor, Drysol
How Aluminum Chloride interacts with Vegan Vitamin D 800 IU — through 1 ingredient. Tap an ingredient for the detail:
Vitamin D2Aluminum Moderate
Interaction Summary
Vitamin D might increase aluminum absorption and toxicity, but this has only been reported in people with renal failure.
Read the full Vitamin D2 + Aluminum Chloride interactionAluminum HydroxideAlu-Cap, Amphojel, Gaviscon
How Aluminum Hydroxide interacts with Vegan Vitamin D 800 IU — through 1 ingredient. Tap an ingredient for the detail:
Vitamin D2Aluminum Moderate
Interaction Summary
Vitamin D might increase aluminum absorption and toxicity, but this has only been reported in people with renal failure.
Read the full Vitamin D2 + Aluminum Hydroxide interactionAluminum Hydroxide, Aspirin, Codeine Phosphate, Magnesium HydroxideAscriptin Codeine #2
How Aluminum Hydroxide, Aspirin, Codeine Phosphate, Magnesium Hydroxide interacts with Vegan Vitamin D 800 IU — through 1 ingredient. Tap an ingredient for the detail:
Vitamin D2Aluminum Moderate
Interaction Summary
Vitamin D might increase aluminum absorption and toxicity, but this has only been reported in people with renal failure.
Read the full Vitamin D2 + Aluminum Hydroxide, Aspirin, Codeine Phosphate, Magnesium Hydroxide interactionAluminum Hydroxide, Aspirin, Magnesium HydroxideAscriptin
How Aluminum Hydroxide, Aspirin, Magnesium Hydroxide interacts with Vegan Vitamin D 800 IU — through 1 ingredient. Tap an ingredient for the detail:
Vitamin D2Aluminum Moderate
Interaction Summary
Vitamin D might increase aluminum absorption and toxicity, but this has only been reported in people with renal failure.
Read the full Vitamin D2 + Aluminum Hydroxide, Aspirin, Magnesium Hydroxide interactionAluminum Hydroxide, Magnesium Hydroxide (otc Drug)Maalox, Mucogel
How Aluminum Hydroxide, Magnesium Hydroxide (otc Drug) interacts with Vegan Vitamin D 800 IU — through 1 ingredient. Tap an ingredient for the detail:
Vitamin D2Aluminum Moderate
Interaction Summary
Vitamin D might increase aluminum absorption and toxicity, but this has only been reported in people with renal failure.
Read the full Vitamin D2 + Aluminum Hydroxide, Magnesium Hydroxide (otc Drug) interactionAluminum Hydroxide, Magnesium Hydroxide, Simethicone (otc Drug)Mylanta
How Aluminum Hydroxide, Magnesium Hydroxide, Simethicone (otc Drug) interacts with Vegan Vitamin D 800 IU — through 1 ingredient. Tap an ingredient for the detail:
Vitamin D2Aluminum Moderate
Interaction Summary
Vitamin D might increase aluminum absorption and toxicity, but this has only been reported in people with renal failure.
Read the full Vitamin D2 + Aluminum Hydroxide, Magnesium Hydroxide, Simethicone (otc Drug) interactionAluminum, CalciumDomeboro
How Aluminum, Calcium interacts with Vegan Vitamin D 800 IU — through 1 ingredient. Tap an ingredient for the detail:
Vitamin D2Aluminum Moderate
Interaction Summary
Vitamin D might increase aluminum absorption and toxicity, but this has only been reported in people with renal failure.
Read the full Vitamin D2 + Aluminum, Calcium interactionAluminum, Magnesium (otc Drug)Almagel
How Aluminum, Magnesium (otc Drug) interacts with Vegan Vitamin D 800 IU — through 1 ingredient. Tap an ingredient for the detail:
Vitamin D2Aluminum Moderate
Interaction Summary
Vitamin D might increase aluminum absorption and toxicity, but this has only been reported in people with renal failure.
Read the full Vitamin D2 + Aluminum, Magnesium (otc Drug) interactionAluminum, Magnesium Hydroxide (otc Drug)Wingel
How Aluminum, Magnesium Hydroxide (otc Drug) interacts with Vegan Vitamin D 800 IU — through 1 ingredient. Tap an ingredient for the detail:
Vitamin D2Aluminum Moderate
Interaction Summary
Vitamin D might increase aluminum absorption and toxicity, but this has only been reported in people with renal failure.
Read the full Vitamin D2 + Aluminum, Magnesium Hydroxide (otc Drug) interactionAmiloride, HydrochlorothiazideAmil-Co, Amilzide, Moduret 25, Moduretic
How Amiloride, Hydrochlorothiazide interacts with Vegan Vitamin D 800 IU — through 1 ingredient. Tap an ingredient for the detail:
Vitamin D2Thiazide Diuretics Moderate
Interaction Summary
Theoretically, taking thiazide diuretics and high-dose vitamin D can increase the risk of hypercalcemia.
Read the full Vitamin D2 + Amiloride, Hydrochlorothiazide interactionAspirin, Aluminum Hydroxide, Codeine Phosphate, Magnesium HydroxideAscriptin Codeine #3
How Aspirin, Aluminum Hydroxide, Codeine Phosphate, Magnesium Hydroxide interacts with Vegan Vitamin D 800 IU — through 1 ingredient. Tap an ingredient for the detail:
Vitamin D2Aluminum Moderate
Interaction Summary
Vitamin D might increase aluminum absorption and toxicity, but this has only been reported in people with renal failure.
Read the full Vitamin D2 + Aspirin, Aluminum Hydroxide, Codeine Phosphate, Magnesium Hydroxide interactionAtenolol, ChlortalidoneAtenixCo, Tenoret 50, Totaretic
How Atenolol, Chlortalidone interacts with Vegan Vitamin D 800 IU — through 1 ingredient. Tap an ingredient for the detail:
Vitamin D2Thiazide Diuretics Moderate
Interaction Summary
Theoretically, taking thiazide diuretics and high-dose vitamin D can increase the risk of hypercalcemia.
Read the full Vitamin D2 + Atenolol, Chlortalidone interactionAtenolol, ChlorthalidoneTenoretic
How Atenolol, Chlorthalidone interacts with Vegan Vitamin D 800 IU — through 1 ingredient. Tap an ingredient for the detail:
Vitamin D2Thiazide Diuretics Moderate
Interaction Summary
Theoretically, taking thiazide diuretics and high-dose vitamin D can increase the risk of hypercalcemia.
Read the full Vitamin D2 + Atenolol, Chlorthalidone interactionAtorvastatinAtorvaliq
How Atorvastatin interacts with Vegan Vitamin D 800 IU — through 1 ingredient. Tap an ingredient for the detail:
Vitamin D2Cytochrome P450 3a4 (cyp3a4) Substrates, Atorvastatin (lipitor) Moderate
Interaction Summary
Vitamin D might induce CYP3A4 enzymes and reduce the bioavailability of CYP3A4 substrates.
Read the full Vitamin D2 + Atorvastatin interactionAtorvastatin CalciumLipitor
How Atorvastatin Calcium interacts with Vegan Vitamin D 800 IU — through 1 ingredient. Tap an ingredient for the detail:
Vitamin D2Atorvastatin (lipitor), Cytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Vitamin D might reduce absorption of atorvastatin.
Read the full Vitamin D2 + Atorvastatin Calcium interactionAzilsartan, ChlorthalidoneEdarbyclor
How Azilsartan, Chlorthalidone interacts with Vegan Vitamin D 800 IU — through 1 ingredient. Tap an ingredient for the detail:
Vitamin D2Thiazide Diuretics Moderate
Interaction Summary
Theoretically, taking thiazide diuretics and high-dose vitamin D can increase the risk of hypercalcemia.
Read the full Vitamin D2 + Azilsartan, Chlorthalidone interactionBenazepril, HydrochlorothiazideLotensin HCT
How Benazepril, Hydrochlorothiazide interacts with Vegan Vitamin D 800 IU — through 1 ingredient. Tap an ingredient for the detail:
Vitamin D2Thiazide Diuretics Moderate
Interaction Summary
Theoretically, taking thiazide diuretics and high-dose vitamin D can increase the risk of hypercalcemia.
Read the full Vitamin D2 + Benazepril, Hydrochlorothiazide interactionBendroflumethiazideAprinox, Naturetin, Neo-NaClex
How Bendroflumethiazide interacts with Vegan Vitamin D 800 IU — through 1 ingredient. Tap an ingredient for the detail:
Vitamin D2Thiazide Diuretics Moderate
Interaction Summary
Theoretically, taking thiazide diuretics and high-dose vitamin D can increase the risk of hypercalcemia.
Read the full Vitamin D2 + Bendroflumethiazide interactionBendroflumethiazide, NadololCorzide
How Bendroflumethiazide, Nadolol interacts with Vegan Vitamin D 800 IU — through 1 ingredient. Tap an ingredient for the detail:
Vitamin D2Thiazide Diuretics Moderate
Interaction Summary
Theoretically, taking thiazide diuretics and high-dose vitamin D can increase the risk of hypercalcemia.
Read the full Vitamin D2 + Bendroflumethiazide, Nadolol interactionBendroflumethiazide, PotassiumCentyl K, Neo-NaClex-K
How Bendroflumethiazide, Potassium interacts with Vegan Vitamin D 800 IU — through 1 ingredient. Tap an ingredient for the detail:
Vitamin D2Thiazide Diuretics Moderate
Interaction Summary
Theoretically, taking thiazide diuretics and high-dose vitamin D can increase the risk of hypercalcemia.
Read the full Vitamin D2 + Bendroflumethiazide, Potassium interactionBendroflumethiazide, Rauwolfia SerpentinaRauzide
How Bendroflumethiazide, Rauwolfia Serpentina interacts with Vegan Vitamin D 800 IU — through 1 ingredient. Tap an ingredient for the detail:
Vitamin D2Thiazide Diuretics Moderate
Interaction Summary
Theoretically, taking thiazide diuretics and high-dose vitamin D can increase the risk of hypercalcemia.
Read the full Vitamin D2 + Bendroflumethiazide, Rauwolfia Serpentina interactionBenzthiazideExna
How Benzthiazide interacts with Vegan Vitamin D 800 IU — through 1 ingredient. Tap an ingredient for the detail:
Vitamin D2Thiazide Diuretics Moderate
Interaction Summary
Theoretically, taking thiazide diuretics and high-dose vitamin D can increase the risk of hypercalcemia.
Read the full Vitamin D2 + Benzthiazide interactionBetamethasone Dipropionate, CalcipotrieneEnstilar, Wynzora
How Betamethasone Dipropionate, Calcipotriene interacts with Vegan Vitamin D 800 IU — through 1 ingredient. Tap an ingredient for the detail:
Vitamin D2Calcipotriene (dovonex) Moderate
Interaction Summary
Taking calcipotriene with vitamin D increases the risk for hypercalcemia.
Read the full Vitamin D2 + Betamethasone Dipropionate, Calcipotriene interactionBisoprolol, HydrochlorothiazideZiac
How Bisoprolol, Hydrochlorothiazide interacts with Vegan Vitamin D 800 IU — through 1 ingredient. Tap an ingredient for the detail:
Vitamin D2Thiazide Diuretics Moderate
Interaction Summary
Theoretically, taking thiazide diuretics and high-dose vitamin D can increase the risk of hypercalcemia.
Read the full Vitamin D2 + Bisoprolol, Hydrochlorothiazide interactionCalcipotrieneDovonex
How Calcipotriene interacts with Vegan Vitamin D 800 IU — through 1 ingredient. Tap an ingredient for the detail:
Vitamin D2Calcipotriene (dovonex) Moderate
Interaction Summary
Taking calcipotriene with vitamin D increases the risk for hypercalcemia.
Read the full Vitamin D2 + Calcipotriene interactionCandesartan Cilexetil, HydrochlorothiazideAtacand HCT
How Candesartan Cilexetil, Hydrochlorothiazide interacts with Vegan Vitamin D 800 IU — through 1 ingredient. Tap an ingredient for the detail:
Vitamin D2Thiazide Diuretics Moderate
Interaction Summary
Theoretically, taking thiazide diuretics and high-dose vitamin D can increase the risk of hypercalcemia.
Read the full Vitamin D2 + Candesartan Cilexetil, Hydrochlorothiazide interactionCaptopril, HydrochlorothiazideAcezide, Capozide
How Captopril, Hydrochlorothiazide interacts with Vegan Vitamin D 800 IU — through 1 ingredient. Tap an ingredient for the detail:
Vitamin D2Thiazide Diuretics Moderate
Interaction Summary
Theoretically, taking thiazide diuretics and high-dose vitamin D can increase the risk of hypercalcemia.
Read the full Vitamin D2 + Captopril, Hydrochlorothiazide interactionChlorothiazideDiuril
How Chlorothiazide interacts with Vegan Vitamin D 800 IU — through 1 ingredient. Tap an ingredient for the detail:
Vitamin D2Thiazide Diuretics Moderate
Interaction Summary
Theoretically, taking thiazide diuretics and high-dose vitamin D can increase the risk of hypercalcemia.
Read the full Vitamin D2 + Chlorothiazide interactionEach ingredient & the kinds of drugs it affects
For each ingredient in Vegan Vitamin D 800 IU with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.
Vitamin D2
Aluminum
Vitamin D might increase aluminum absorption and toxicity, but this has only been reported in people with renal failure.
The protein that transports calcium across the intestinal wall can also bind and transport aluminum. This protein is stimulated by vitamin D, which may therefore increase aluminum absorption. This mechanism may contribute to increased aluminum levels and toxicity in people with renal failure, when they take vitamin D and aluminum-containing phosphate binders chronically.
Atorvastatin (Lipitor)
Vitamin D might reduce absorption of atorvastatin.
A small, low-quality clinical study shows that taking vitamin D reduces levels of atorvastatin and its active metabolites by up to 55%. However, while atorvastatin levels decreased, total cholesterol, low-density lipoprotein (LDL) cholesterol, and high-density lipoprotein (HDL) cholesterol levels did not substantially change. Atorvastatin is metabolized in the gut by CYP3A4 enzymes, and researchers theorized that vitamin D might induce CYP3A4, causing reduced levels of atorvastatin. However, this proposed mechanism was not specifically studied.
Calcipotriene (Dovonex)
Taking calcipotriene with vitamin D increases the risk for hypercalcemia.
Calcipotriene is a vitamin D analog used topically for psoriasis. It can be absorbed in sufficient amounts to cause systemic effects, including hypercalcemia. Theoretically, combining calcipotriene with vitamin D supplements might increase the risk of hypercalcemia.
Digoxin (Lanoxin)
Theoretically, hypercalcemia induced by high-dose vitamin D can increase the risk of arrhythmia from digoxin.
High doses of vitamin D can cause hypercalcemia. Hypercalcemia increases the risk of fatal cardiac arrhythmias with digoxin. Avoid vitamin D doses above the tolerable upper intake level (4000 IU daily for adults) and monitor serum calcium levels in people taking vitamin D and digoxin concurrently.
Diltiazem (Cardizem, Others)
Theoretically, hypercalcemia induced by high-dose vitamin D can reduce the therapeutic effects of diltiazem for arrhythmia.
High doses of vitamin D can cause hypercalcemia. Hypercalcemia can reduce the effectiveness of verapamil in atrial fibrillation. Theoretically this could also occur with diltiazem. Avoid vitamin D doses above the tolerable upper intake level (4000 IU daily for adults) and monitor serum calcium levels in people taking vitamin D and diltiazem concurrently.
Thiazide Diuretics
Theoretically, taking thiazide diuretics and high-dose vitamin D can increase the risk of hypercalcemia.
Thiazide diuretics decrease urinary calcium excretion, which could lead to hypercalcemia if vitamin D supplements are taken concurrently. This has been reported in people being treated with vitamin D for hypoparathyroidism, and also in elderly people with normal parathyroid function who were taking a thiazide, vitamin D, and calcium-containing antacids daily.
Verapamil (Calan, Others)
Hypercalcemia induced by high-dose vitamin D can reduce the therapeutic effects of verapamil for arrhythmia.
Hypercalcemia due to high doses of vitamin D can reduce the effectiveness of verapamil in atrial fibrillation. Avoid vitamin D doses above the tolerable upper intake level (4000 IU daily for adults) and monitor serum calcium levels in people taking vitamin D and verapamil concurrently.
Cytochrome P450 3A4 (Cyp3A4) Substrates
Vitamin D might induce CYP3A4 enzymes and reduce the bioavailability of CYP3A4 substrates.
There is some concern that vitamin D might induce CYP3A4. In vitro research suggests that vitamin D induces CYP3A4 transcription. Additionally, observational research has found that increased UV light exposure and serum vitamin D levels are associated with decreased serum levels of CYP3A4 substrates such as tacrolimus and sirolimus, while no association between UV light exposure or vitamin D levels and levels of mycophenolic acid, a non-CYP3A4 substrate, was found. A small, low-quality clinical study shows that taking vitamin D reduces levels of the CYP3A4 substrate atorvastatin and its active metabolites by up to 55%; however, the clinical effects of atorvastatin were not reduced. While researchers theorized that vitamin D might induce CYP3A4, this proposed mechanism was not specifically studied.
Brand information
Manufacturer and brand details for Vegan Vitamin D 800 IU, from the product label.
DEVA
See all DEVA products- Name
- DEVA Nutrition LLC
- Phone Number
- (888)988-3382
- Web Address
- www.devanutrition.com
Vegan Vitamin D 800 IU by DEVA: Common Questions
Does Vegan Vitamin D 800 IU by DEVA interact with any medications?
How can one product interact with so many drugs?
Where does this information come from?
Is 800 IU a safe dose of vitamin D?
Can I take this while pregnant or breastfeeding?
What does vitamin D do in the body?
What side effects should I watch for?
Why is this vegan?
Can this product reduce how well my other medications work?
Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
Not sure if Vegan Vitamin D 800 IU is safe with your meds?
Our pharmacists answer your medication & supplement questions — free.
Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.
The Full Monographs Behind Vegan Vitamin D 800 IU’s Ingredients
Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.
Sources & How We Checked
Vegan Vitamin D 800 IU's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.
- NIH Dietary Supplement Label Database (DSLD) — The official product label on file for this supplement.
- Natural Medicines (Therapeutic Research Center) — Evidence-graded clinical reference behind the ingredient interaction data.
Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.
The 26 references behind this product’s interaction data
Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.
Vitamin D 26 references
- McEvoy GK, ed. AHFS Drug Information. Bethesda, MD: American Society of Health-System Pharmacists, 1998.
- Tatro DS, ed. Drug Interactions Facts. Facts and Comparisons Inc., St. Louis, MO. 1999.
- Koutkia P, Chen TC, Holick MF. Vitamin D intoxication associated with an over-the-counter supplement. N Engl J Med 2001;345:66-7. PubMed
- Bar-Or D, Yoel G. Calcium and calciferol antagonize effect of verapamil in atrial fibrillation. Br Med J 1981;282:1585-6.
- Demontis R, Leflon A, Fournier A, et al. 1 alpha(OH) vitamin D3 increases plasma aluminum in hemodialyzed patients taking AI(OH)3. Clin Nephrol 1986;26:146-9.
- Crowe M, Wollner L, Griffiths RA. Hypercalcemia following vitamin D and thiazide therapy in the elderly. Practitioner 1984;228:312-3.
- Parfitt AM. Thiazide-induced hypercalcemia in vitamin D-treated hypoparathyroidism. Ann Intern Med 1972;77:557-63. PubMed
- Thiazide diuretics and the risk of osteoporosis. Pharmacist's Letter/Prescriber's Letter 2003;19(11):191105.
- Moon J. The role of vitamin D in toxic metal absorption. J Am Coll Nutr 1994;13:559-64.
- Demontis R, Reissi D, Noel C, et al. Indirect clinical evidence that 1alphaOH vitamin D<SUB>3</SUB> increases the intestinal absorption of aluminum. Clin Nephrol 1989;31:123-7.
- Adler AJ, Berlyne GM. Duodenal aluminum absorption in the rat: effect of vitamin D. Am J Physiol 1985;249:G209-13. PubMed
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- Dietary reference intakes for calcium and vitamin D. Institute of Medicine, November 30, 2010. Available at: http://www.iom.edu/~/media/Files/Report%20Files/2010/Dietary-Reference-Intakes-for-Calcium-and-Vitamin-D/Vitamin%20D%20and%20Calcium%202010%20Repo
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DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.
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