Major interaction on record — check this product against your medications before combining. Check your meds →
Dietary supplement

Vision Health With Lutein Ingredients & Drug Interactions

by Nutrilite

Vision Health With Lutein label
See full label image
Tablet Or Pill Category: Other Combinations
Most serious interaction: Major
Clinical methodology reviewed by · Updated Sep 16, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Vision Health With Lutein against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Major

Vision Health With Lutein is a dietary supplement by Nutrilite with 5 active ingredients. Its ingredients are commonly taken for eye and vision health, antioxidant support, diarrhea and digestive upset.Based on those ingredients, 588 medications have a known interaction with it, the most serious rated major. The ingredients most likely to interact are Vitamin A, Bilberry extract, Black Currant extract. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

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Check Your Meds Against Vision Health With Lutein by Nutrilite

Ask about any prescription or over-the-counter medication and we check it for interactions with Vision Health With Lutein by Nutrilite — and tell you which ingredient is responsible.

Pharmacist-reviewed data Checks every ingredient Answer in seconds
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HelloPharmacist Scorecard of Vision Health With Lutein by Nutrilite

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Jul 11, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 5 of its 5 active ingredients.
  • No proprietary blends here — you can verify the dose of every single component.

This product has 5 active ingredients formulated for eye health. Bilberry extract, vitamin A, and spinach concentrate deliver antioxidants and nutrients with a track record in eye-supporting formulations.

Lutein is a carotenoid — a plant pigment your eyes naturally contain and concentrate in the macula, the central part of the retina responsible for sharp vision. Black currant extract rounds out the blend with gamma-linolenic acid and additional antioxidants.

The tablet also contains several inactive ingredients — cellulose, starch, silica, gums, and wax — which serve as binders, fillers, and coatings.

Does it work?

Moderate evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Moderate

Some clinical evidence supports this product's ingredients for its stated purpose, but it isn't conclusive.

Why this rating?
  • The label markets this product for: support eye health and vision as eyes age.
  • We looked for evidence on: Age-related macular degeneration (AMD), Asthenopia (eye strain), Cataracts, Diabetic retinopathy, Dry eye, Glaucoma — and 4 related terms.
  • The strongest evidence on file: Lutein is rated "Possibly Effective" for Age-related macular degeneration (AMD) (Natural Medicines).
  • Also on file: Lutein is rated "Possibly Effective" for Cataracts.
  • Also on file: Bilberry is rated "Insufficient Reliable Evidence To Rate" for Age-related macular degeneration (AMD), Cataracts, Diabetic retinopathy, Dry eye, and more.

The evidence backing each ingredient varies. Vitamin A is rated Effective for vitamin A deficiency and Possibly Effective for conditions including aging skin and measles; evidence on its eye-specific benefits here is not detailed in our data.

Lutein is Possibly Effective for age-related macular degeneration and cataracts — the two eye conditions most relevant to a vision product. Bilberry, black currant, and spinach do not have established effectiveness ratings for vision or eye health in our data; we hold insufficient reliable evidence for bilberry's role in night vision and age-related macular degeneration, and insufficient evidence for black currant and spinach across their listed conditions.

The evidence, ingredient by ingredient Bilberry Vitamin A Lutein Black Currant Spinach

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 5 of the 5 matched ingredients.
  • Pregnancy & breastfeeding safety ratings cover 5 of 5.
  • General safety write-ups exist for 5 of 5.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

The ingredients are generally well tolerated at the doses expected in a supplement. Lutein and spinach are well tolerated at typical levels; lutein doses up to 20 mg daily have not caused adverse effects.

Bilberry and black currant are safe as foods but supplement-specific safety data is limited — the facts advise caution with concentrated doses. Vitamin A's safety depends heavily on dose: at recommended amounts it's well tolerated, but high doses accumulate in your body and can cause serious toxicity including liver damage, headache, and skin problems.

The safety notes flag that high-dose vitamin A in pregnancy is possibly unsafe and can cause birth defects; recommended amounts are appropriate. Black currant seed oil produced mild diarrhea in a small number of people in one study.

Bilberry may cause dark-colored stools, flatulence, and stomach discomfort; one small trial reported flatulence in about a third of patients, though that group had ulcerative colitis. Spinach is safe as food during pregnancy and breastfeeding; no adverse effects are expected at normal food intake.

Side effects, ingredient by ingredient Bilberry Vitamin A Lutein Black Currant Spinach

Meds to double-check

Major interaction found
Known Interaction Concern · database check
Major identified

At least one ingredient has a documented Major-severity interaction. Check your medications for a personalized result.

Why this rating?
  • 4 of the 5 matched ingredients can interact with medications — Bilberry, Spinach, Vitamin A, Black Currant.
  • The most serious interaction on file is rated Major.
  • Some involve high-stakes drug classes: anticoagulant / antiplatelet drugs; diabetes medications.
  • For scale: 589 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Double-check this product if you take blood thinners (anticoagulants) like warfarin or antiplatelet drugs like aspirin — multiple ingredients increase bleeding risk. If you take diabetes medications, spinach and bilberry may lower blood sugar further.

Tetracycline antibiotics (like doxycycline) have a Moderate concern with the vitamin A in this product. Phenothiazines (used for psychosis or severe nausea) conflict with black currant.

Do not use if you take retinoid drugs like isotretinoin — Major severity due to vitamin A. Run your complete medication list through the search tool on this page.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with some supporting evidence for its stated purpose. Major medication interactions have been identified, and safety information is well characterized.

If you have age-related macular degeneration or cataracts, lutein may be worth discussing with your eye doctor. This product is a reasonable choice for general eye-health support in someone not on blood thinners, diabetes medications, retinoid drugs, or phenothiazines.

Because vitamin A is included, confirm with your pharmacist that the dose won't conflict with any medications or supplements you're already taking — especially if you're on a blood thinner or high-dose vitamins. Talk to us before you start.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 5 of 5 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated May 24, 2018.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Vision Health With Lutein, straight from the product label.

Brand Nutrilite
Barcode (UPC) 10-4144
Net contents 62 Tablet(s)
Market status On market
Date entered into DSLD May 24, 2018
DSLD ID 177378
Product type Other Combinations
Supplement form Tablet Or Pill
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years), Kosher, Halal
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Vision Health With Lutein by Nutrilite, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
2 Tablet(s)
Maximum serving Sizes:
2 Tablet(s)
UPC/BARCODE
10-4144
IngredientAmount% DV
Bilberry extract100 mg--
Vitamin A700 IU14%
Lutein10 mg--
Black Currant extract50 mg--
Spinach concentrate30 mg--

Other ingredients: Microcystalline Cellulose, Corn Starch, Stearic Acid, Cellulose Gum, Silicon Dioxide, Hydroxypropyl Methylcellulose, Glycerin, Carnauba wax

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
General Statements

Help keep your eyes shining bright with this supplement!

This formula also can help maintain blood vessel integrity. Don't forget all the other ways to protect/support your eyes as they age: Wear sunglasses outdoors, use appropriate lighting when reading and on the computer, and get plenty of rest. Your eyes will thank you.

Support visual sharpness

Quality you can trust since 1934

Exclusively from Amway

Formula

It contains Lutein at a level that's clinically proven to support and replenish antioxidant levels in your healthy retinas and macula.

Contains soy

Star-K

crescent M

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

Precautions

Children under 12 years of age, pregnant women or nursing mothers, or anyone with a medical condition should consult with a physician before taking this product. Keep out of reach of children.

Children under 12 years of age, pregnant women or nursing mothers, or anyone with a medical condition should consult with a physician before taking this product.

Contains soy

Storage

Keep bottle tightly closed. Store in a cool, dry place.

FDA Statement of Identity

Dietary Supplement

Suggested/Recommended/Usage/Directions

2 tablets, 1x a day

Suggested use: Two tablets once daily with food.

General

1044302

Seals/Symbols

NSF Contents tested & certified Star-K crescent M

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Vision Health With Lutein by Nutrilite label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Vision Health With Lutein label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Vision Health With Lutein by Nutrilite

These are the 5 active ingredients this product is made of. Select any to open its full monograph.

Serving size2 Tablet(s) Dosage formTablet Or Pill Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

Bilberry extract

Interacts with
275 drugs
100 mg per serving

Bilberry is a blueberry-like fruit rich in antioxidant plant compounds called anthocyanins, and it has a long history of traditional use for eye healt...

Bilberry extract monograph & interactions

Vitamin A

Interacts with
387 drugs
700 IU per serving Form: Vitamin A Acetate

Vitamin A is an essential nutrient important for vision, skin, immune function, and growth. Most people get enough from a balanced diet, and supplemen...

Vitamin A monograph & interactions

Lutein

No known
interactions
10 mg per serving Form: Aztec Marigold, Lutein Ester Beadlets

Lutein is a plant-based antioxidant pigment that concentrates in the eye, and the best evidence suggests it (often combined with zeaxanthin) may help...

Lutein monograph & interactions

Black Currant extract

Interacts with
140 drugs
50 mg per serving Form: Black Currant extract, Maltodextrin

Black currant is a nutritious berry that is rich in vitamin C and antioxidants, and its seed oil contains the omega-6 fatty acid GLA. While it is enjo...

Black Currant extract monograph & interactions

Spinach concentrate

Interacts with
88 drugs
30 mg per serving

Spinach is a nutrient-dense leafy green that is a healthy part of a balanced diet, providing vitamins, minerals, fiber, and antioxidants. While it is...

Spinach concentrate monograph & interactions

Other (inactive) ingredients: Microcystalline Cellulose, Corn Starch, Stearic Acid, Cellulose Gum, Silicon Dioxide, Hydroxypropyl Methylcellulose, Glycerin, Carnauba wax. These complete the product’s ingredient list but are not active constituents.

Interaction report

Vision Health With Lutein by Nutrilite Drug Interactions

Want to check YOUR meds against Vision Health With Lutein?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
588Drugs
9 Major 579 Moderate

Ingredients driving the most interactions

Vitamin A 387
Bilberry extract 275
Black Currant extract 140
Spinach concentrate 88

Individual Drug Interactions

The ingredients in Vision Health With Lutein interact with 588 drugs. Click any drug to see the details.

4 of the 5 ingredients in Vision Health With Lutein interact with drugs. Each result below shows which ingredient is responsible. Vitamin A Bilberry extract Black Currant extract Spinach concentrate

Each ingredient & the kinds of drugs it affects

For each ingredient in Vision Health With Lutein with known interactions, here are the types of medications they can affect. Open any type for the detail — or search your exact drug in the checker above.

Vitamin A4 drug types · 387 drugs

Retinoids

Concomitant use of retinoids with vitamin A supplements might produce supratherapeutic vitamin A levels.
Retinoids, which are vitamin A derivatives, could have additive toxic effects when taken with vitamin A supplements.

Likelihood Probable Evidence D
Hepatotoxic Drugs

Theoretically, taking high doses of vitamin A in combination with other potentially hepatotoxic drugs might increase the risk of liver disease.
The tolerable upper intake level (UL) is the highest level of intake that is likely to pose no risk of adverse effects. Doses of vitamin A above the UL can cause hepatotoxicity, ranging from elevated liver enzymes to liver failure.

Likelihood Possible Evidence C
Tetracycline Antibiotics

Theoretically, taking tetracycline antibiotics with high doses of vitamin A can increase the risk of pseudotumor cerebri.
Benign intracranial hypertension (pseudotumor cerebri) can occur with tetracyclines and with acute or chronic vitamin A toxicity. Case reports suggest that taking tetracyclines and vitamin A concurrently can increase the risk of this condition. Avoid high doses of vitamin A in people taking tetracyclines chronically.

Likelihood Possible Evidence D
Warfarin (Coumadin)

Theoretically, high doses of vitamin A could increase the risk of bleeding with warfarin.
Vitamin A toxicity is associated with hemorrhage and hypoprothrombinemia, possibly due to vitamin K antagonism. Advise patients taking warfarin to avoid doses of vitamin A above the tolerable upper intake level of 10,000 IU/day for adults.

Likelihood Possible Evidence D
Vitamin A full monograph & interactions

Bilberry extract4 drug types · 275 drugs

Anticoagulant/Antiplatelet Drugs

Theoretically, bilberry fruit extract might increase the risk of bleeding when taken with anticoagulant or antiplatelet drugs.
In vitro, animal, and clinical research suggest that anthocyanidin extracts from bilberry can inhibit platelet aggregation.

Likelihood Possible Evidence D
Antidiabetes Drugs

Theoretically, bilberry leaf or fruit extract may increase the risk of hypoglycemia when taken with antidiabetes drugs.
Animal research suggests that bilberry leaf extract might have blood glucose-lowering activity. Also, one small clinical trial in patients with type 2 diabetes shows that taking bilberry fruit extract 470 mg as a single dose prior to an oral glucose tolerance test lowers plasma glucose levels when compared with placebo.

Likelihood Possible Evidence D
Cytochrome P450 2E1 (Cyp2E1) Substrates

Theoretically, bilberry fruit extract might decrease levels of drugs metabolized by CYP2E1.
Animal research shows that exposure to small concentrations of bilberry extract in drinking water for around one month increased CYP2E1 activity by 31%. However, exposure over a 2-month period did not increase CYP2E1 activity. This effect has not been reported in humans.

Likelihood Possible Evidence D
Erlotinib (Tarceva)

Theoretically, bilberry fruit extract might reduce the efficacy of erlotinib.
In vitro research suggests that bilberry fruit extract and its constituents, delphinidin and delphinidin-3-O-glucoside, inhibit the activity of erlotinib. This interaction has not been reported in humans.

Likelihood Possible Evidence D
Bilberry extract full monograph & interactions

Black Currant extract2 drug types · 140 drugs

Anticoagulant/Antiplatelet Drugs

Theoretically, black currant seed oil might increase the risk of bleeding if used in combination with anticoagulant or antiplatelet drugs.
Gamma-linolenic acid (GLA), a constituent of black currant seed oil, appears to have antiplatelet effects.

Likelihood Possible Evidence D
Phenothiazines

Theoretically, black currant seed oil might increase the risk of seizure in patients receiving phenothiazines.
Black currant seed oil contains gamma-linolenic acid (GLA). There is some concern that taking supplements containing GLA might cause seizures, or lower the seizure threshold, when taken with phenothiazines, although there is no evidence that black currant seed oil causes seizures. In one report, three patients with schizophrenia who had received phenothiazines developed EEG changes suggestive of temporal lobe epilepsy after starting treatment with GLA, although none experienced an actual seizure. In another report, two patients with schizophrenia who were stabilized on phenothiazines developed seizures when evening primrose 4 grams daily, which contains GLA, was added. One of these patients had a prior history of seizures.

Likelihood Possible Evidence D
Black Currant extract full monograph & interactions

Spinach concentrate2 drug types · 88 drugs

Antidiabetes Drugs

There are claims that spinach leaves have hypoglycemic effects. Evidence from clinical research suggests that consumption of a spinach-rich meal reduces post-meal blood glucose levels. Theoretically, spinach might have additive effects with antidiabetes drugs and increase the risk of hypoglycemia. Monitor blood glucose levels closely. Dose adjustments might be necessary. Some antidiabetes drugs include glimepiride (Amaryl), glyburide (DiaBeta, Glynase PresTab, Micronase), insulin, pioglitazone (Actos), rosiglitazone (Avandia), and others.

Likelihood Possible Evidence D
Warfarin (Coumadin)

Spinach contains vitamin K, which can interfere with the activity of warfarin.
In human research, although eating spinach with one meal does not result in coagulation test results outside the therapeutic range, daily consumption for one week necessitates dose adjustment of warfarin. Individuals using anticoagulants should consume a consistent daily amount of spinach to maintain the effect of anticoagulant therapy.

Likelihood Possible Evidence D
Spinach concentrate full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Vision Health With Lutein, from the product label.

Nutrilite

See all Nutrilite products
Name
Amway Corp.
City
Ada
State
MI
ZipCode
49355
Phone Number
1-800-253-6500
Web Address
Amway.com/Nutrilite
Pharmacist Counseling Corner

Vision Health With Lutein by Nutrilite: Common Questions

Does Vision Health With Lutein by Nutrilite interact with any medications?
Yes. Based on its ingredients, Vision Health With Lutein has a known interaction with 588 medications, including 9 rated major. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Vision Health With Lutein contains 5 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Does this product work for dry eyes or presbyopia (age-related focus problems)?
The data we hold doesn't cover those conditions. Lutein is Possibly Effective for age-related macular degeneration and cataracts. If you have a specific eye condition, ask your eye doctor whether this product's ingredients match what evidence supports.
I'm pregnant. Is this safe to take?
Bilberry, lutein, and spinach are rated Likely Safe in pregnancy. Vitamin A is Likely Safe at recommended amounts, but Possibly Unsafe at high doses — high-dose vitamin A can cause birth defects. This product should be fine, but mention it to your obstetrician to confirm the vitamin A level matches your prenatal plan.
Will this make my stool or tongue dark?
Yes. Bilberry can cause dark-colored stools and, in some people, dark discoloration of the tongue and teeth. This is harmless — it's the bilberry pigment — but it's worth knowing about.
What does lutein actually do?
Lutein is a carotenoid pigment naturally found in your eyes, especially in the macula — the central part of the retina that gives you sharp, detailed vision. It acts as an antioxidant and may help protect the macula from age-related damage.
I have type 2 diabetes. Can I take this?
Both bilberry and spinach have Moderate interactions with diabetes medications — they may lower blood sugar further, increasing low blood sugar risk. Talk to your pharmacist or doctor before starting; you may need glucose monitoring or a medication adjustment.
Can I take this with my multivitamin?
It depends on what's in your multivitamin. If it contains vitamin A, retinoids, or blood thinners, there's a conflict. Check the label and run both products through the medication checker on this page to be safe.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Vision Health With Lutein is safe with your meds?

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Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Vision Health With Lutein label
Go deeper

The Full Monographs Behind Vision Health With Lutein’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Bilberry

Interacts with 275 drugs

Bilberry is a blueberry-like fruit rich in antioxidant plant compounds called anthocyanins, and it has a long history of traditional use for eye health, circulation, and mild diarrhea. While...

Read the full Bilberry monograph → Herb & supplement monograph

Vitamin A

Interacts with 387 drugs

Vitamin A is an essential nutrient important for vision, skin, immune function, and growth. Most people get enough from a balanced diet, and supplements are mainly useful for correcting a tr...

Read the full Vitamin A monograph → Herb & supplement monograph

Lutein

Lutein is a plant-based antioxidant pigment that concentrates in the eye, and the best evidence suggests it (often combined with zeaxanthin) may help slow progression of age-related macular...

Read the full Lutein monograph → Herb & supplement monograph

Black Currant

Interacts with 140 drugs

Black currant is a nutritious berry that is rich in vitamin C and antioxidants, and its seed oil contains the omega-6 fatty acid GLA. While it is enjoyed safely as a food and is popular as a...

Read the full Black Currant monograph → Herb & supplement monograph

Spinach

Interacts with 88 drugs

Spinach is a nutrient-dense leafy green that is a healthy part of a balanced diet, providing vitamins, minerals, fiber, and antioxidants. While it is very safe as a food, concentrated supple...

Read the full Spinach monograph →
Sources

Sources & How We Checked

Vision Health With Lutein's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 59 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Bilberry 14 references
  1. Cignarella A, Nastasi M, Cavalli E, Puglisi L. Novel lipid-lowering properties of Vaccinium myrtillus L. leaves, a traditional antidiabetic treatment, in several models of rat dyslipidaemia: a comparison with ciprofibrate. Thromb Res 1996;84:311-22. PubMed
  2. Morazzoni P, Magistretti MJ. Activity of Myrtocyan, an anthosyanoside complex from Vaccinium myrtillus (VMA), on platelet aggregation and adhesiveness. Fitoterapia 1990;61:13-21.
  3. Erlund, I., Koli, R., Alfthan, G., Marniemi, J., Puukka, P., Mustonen, P., Mattila, P., and Jula, A. Favorable effects of berry consumption on platelet function, blood pressure, and HDL cholesterol. Am J Clin Nutr 2008;87(2):323-331. PubMed
  4. Hawrelak, J. A. and Myers, S. P. Effects of two natural medicine formulations on irritable bowel syndrome symptoms: a pilot study. J Altern Complement Med 2010;16(10):1065-1071. PubMed
  5. Morazzoni P and Magistretti MJ. Effects of Vaccinium myrtillus anthocyanosides on prostacyclin-like activity in rat arterial issue. Fitoterapia 1986;57:11-14.
  6. Pulliero G, Montin S, Bettini V, and et al. Ex vivo study of the inhibitory effects of Vaccinium myrtillus anthocyanosides on human platelet aggregation. Fitoterapia 1989;60:69-75.
  7. Bottecchia D. Preliminary report on the inhibitory effect of vaccinium myrtillus anthocyanosides on platelet aggregation and clot retraction. Fitoterapia 1987;48:3-8.
  8. Fdez, M., Zaragoza, F., and Alvarez, P. In vitro platelet aggregation effects of anthocyanosides of vaccinium myrtilus L. Anales de la Real Academia de Farmacia 1983;49:79-90.
  9. Biedermann L, Mwinyi J, Scharl M, Frei P, Zeitz J, Kullak-Ublick GA, et al. Bilberry ingestion improves disease activity in mild to moderate ulcerative colitis-an open pilot study. 2013 May;7(4):271-9. PubMed
  10. Hoggard N, Cruickshank M, Moar KM, Bestwick C, Holst J, Russell W, et al. A single supplement of a standardized bilberry (Vaccinium myrtillus L.) extract (36% wet weight anthocyanins) modifies glycaemic response in individuals with type 2 diabetes control
  11. Aichinger G, Pahlke G, Nagel LJ, Berger W, Marko D. Bilberry extract, its major phenolic compounds, and soy isoflavone genistein antagonize the cytostatic drug erlotinib in human epithelial cells. Food Funct 2016;7(8):3628-36.
  12. Prokop J, Lněničková K, Cibicek N, et al. Effect of bilberry extract (Vaccinium myrtillus L.) on drug-metabolizing enzymes in rats. Food Chem Toxicol 2019;129:382-90. PubMed
  13. Chan SW, Chu TTW, Choi SW, Benzie IFF, Tomlinson B. Impact of short-term bilberry supplementation on glycemic control, cardiovascular disease risk factors, and antioxidant status in Chinese patients with type 2 diabetes. Phytother Res 2021. Online ahead o PubMed
  14. Bøhn SK, Myhrstad MCW, Thoresen M, et al. Bilberry/red grape juice decreases plasma biomarkers of inflammation and tissue damage in aged men with subjective memory impairment -a randomized clinical trial. BMC Nutr 2021;7(1):75. PubMed

See these in context on the Bilberry monograph →

Vitamin A 31 references
  1. McEvoy GK, ed. AHFS Drug Information. Bethesda, MD: American Society of Health-System Pharmacists, 1998.
  2. Griffiths JK. The vitamin A paradox. J Pediatr 2000;137:604-7.. PubMed
  3. Hardman JG, Limbird LL, Molinoff PB, eds. Goodman and Gillman's The Pharmacological Basis of Therapeutics, 9th ed. New York, NY: McGraw-Hill, 1996.
  4. Hansten PD, Horn JR. Drug Interactions Analysis and Management. Vancouver, WA: Applied Therapeutics Inc., 1997 and updates.
  5. FDA Talk Paper. Vitamin A and birth defects (T95-56). Food and Drug Administration, U.S. Department of Health and Human Services, Rockville, MD. October 6, 1995.
  6. Russell RM. The vitamin A spectrum: from deficiency to toxicity. Am J Clin Nutr 2000;71:878-84. PubMed
  7. Food and Nutrition Board, Institute of Medicine. Dietary Reference Intakes for Vitamin A, Vitamin K, Arsenic, Boron, Chromium, Copper, Iodine, Iron, Manganese, Molybdenum, Nickel, Silicon, Vanadium, and Zinc. Washington, DC: National Academy Press, 2002.
  8. Feskanich D, Singh V, Willett WC, Colditz GA. Vitamin A intake and hip fractures among postmenopausal women. JAMA 2002;287:47-54. PubMed
  9. Melhus H, Michaelsson K, Kindmark A, et al. Excessive dietary intake of vitamin A is associated with reduced bone mineral density and increased risk for hip fracture. Ann Intern Med 1998;129:770-8. PubMed
  10. Michaelsson K, Lithell H, Vessby B, Melhus H. Serum retinol levels and the risk of fracture. N Engl J Med 2003;348:287-94.. PubMed
  11. Botterweck AA, van den Brandt PA, Goldbohm RA. Vitamins, carotenoids, dietary fiber, and the risk of gastric carcinoma: results from a prospective study after 6.3 years of follow-up. Cancer 2000;88:737-48.. DOI
  12. Meyskens FL Jr, Graham V, Chvapil M, et al. A phase I trial of beta-all-trans-retinoic acid delivered via a collagen sponge and a cervical cap for mild or moderate intraepithelial cervical neoplasia. J Natl Cancer Inst 1983;71:921-5..
  13. Hathcock JN, Hattan DG, Jenkins MY, et al. Evaluation of vitamin A toxicity. Am J Clin Nutr 1990;52:183-202.. PubMed
  14. Walters BN, Gubbay SS. Tetracycline and benign intracranial hypertension: report of five cases. Br Med J 1981;282:19-20.. PubMed
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See these in context on the Vitamin A monograph →

Lutein 2 references
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See these in context on the Lutein monograph →

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See these in context on the Black Currant monograph →

Spinach 6 references
  1. Brinker F. Herb Contraindications and Drug Interactions. 2nd ed. Sandy, OR: Eclectic Medical Publications, 1998.
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See these in context on the Spinach monograph →

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DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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