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Dietary supplement

Vitamin B-2 100 Milligrams Ingredients & Drug Interactions

by NutraBio

Vitamin B-2 100 Milligrams label
See full label image
Capsule Category: Vitamin
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 30, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Vitamin B-2 100 Milligrams against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Vitamin B-2 100 Milligrams is a dietary supplement by NutraBio with 1 active ingredient. Its ingredients are commonly taken for riboflavin deficiency, migraine prevention, general energy and metabolism support.Based on those ingredients, 20 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Riboflavin. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

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Check Your Meds Against Vitamin B-2 100 Milligrams by NutraBio

Ask about any prescription or over-the-counter medication and we check it for interactions with Vitamin B-2 100 Milligrams by NutraBio — and tell you which ingredient is responsible.

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HelloPharmacist Scorecard of Vitamin B-2 100 Milligrams by NutraBio

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Sep 24, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

This product contains one active ingredient: riboflavin (also called vitamin B-2), a B vitamin your body needs to convert food into energy and to support cell growth and repair. The capsule also holds rice flour and a vegetable capsule shell as inactive ingredients.

Does it work?

Strong evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed

This product doesn't appear to be marketed for a specific use, so we graded Riboflavin's overall clinical evidence instead.

Strong

Strong clinical evidence supports Riboflavin for:

Why this rating?
  • We looked at the product name, claims, and label statements and couldn't find a stated purpose to grade.
  • Since the label doesn't commit to one use, we graded the ingredient's overall clinical evidence instead.
  • On file: Ariboflavinosis — rated "Effective" (Natural Medicines).
  • On file: Migraine headache — rated "Possibly Effective" (Natural Medicines).
  • On file: Hyperhomocysteinemia — rated "Possibly Effective" (Natural Medicines).

We don't hold effectiveness ratings for riboflavin in our data. What we know is that it's an essential nutrient your body requires for normal energy production and cellular function — but whether this specific supplement dose delivers a measurable benefit beyond meeting your daily requirement isn't established in the information we have on file.

The evidence, ingredient by ingredient Riboflavin

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Riboflavin is generally well tolerated. At this 100 mg dose, the main side effects you might notice are nausea and bright yellow urine — both dose-related.

Excess riboflavin is removed through your urine, so it doesn't build up in your body. Riboflavin is needed during pregnancy and breastfeeding and is considered safe at recommended amounts; if you're taking a high-dose supplement like this one, talk with your doctor or pharmacist first to make sure it's right for you.

Side effects, ingredient by ingredient Riboflavin

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Riboflavin.
  • The most serious interaction on file is rated Moderate.
  • For scale: 20 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

If you take tetracycline antibiotics, check with your doctor or pharmacist before starting this product — riboflavin may reduce their effectiveness, though this hasn't been proven in human studies.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with strong clinical evidence behind its ingredients' uses. Moderate medication interactions have been identified, and safety information is well characterized.

This is a straightforward B-2 supplement that's very well tolerated by most people. The main thing to watch is if you're on tetracycline antibiotics — check with your doctor or pharmacist before you start it.

Otherwise, if you need riboflavin for your health, talk it over with your own healthcare provider to confirm the dose and timing are right for you.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Oct 22, 2015.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Vitamin B-2 100 Milligrams, straight from the product label.

Brand NutraBio
Barcode (UPC) 649908518165
Net contents 120 V-Cap(s)
Market status On market
Date entered into DSLD Oct 22, 2015
DSLD ID 51277
Product type Vitamin
Supplement form Capsule
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Vegetarian, Adult (18 - 50 Years), Kosher, No Allergies, Gluten Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Vitamin B-2 100 Milligrams by NutraBio, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Vegetable Capsule(s)
Maximum serving Sizes:
1 Vegetable Capsule(s)
Servings per container
120
UPC/BARCODE
649908518165
IngredientAmount% DV
Riboflavin100 mg5882%

Other ingredients: Rice Flour, Vegetable Capsule

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Suggested/Recommended/Usage/Directions

1 capsule daily with food Suggested Use: As a dietary supplement, take one (1) capsule daily, preferably with meals, or as directed by your physician.

Formulation

This product is Kosher, Vegetarian, Hypoallergenic, Non-GMO, Gluten Free & BSE/TSE Free.

This product is Kosher, Vegetarian, Hypoallergenic, Non-GMO, Gluten Free & BSE/TSE Free.

Formula

This product is Kosher, Vegetarian, Hypoallergenic, Non-GMO, Gluten Free & BSE/TSE Free.

This product is Kosher, Vegetarian, Hypoallergenic, Non-GMO, Gluten Free & BSE/TSE Free.

Precautions

Warning: NOT INTENDED FOR USE BY PERSONS UNDER THE AGE OF 18. KEEP OUT OF THE REACH OF CHILDREN.

If you are pregnant, breast feeding, have known medical conditions (including kidney or liver disease) or are taking prescription or OTC medication(s) consult with your health care practitioner before using this product.

General Statements

Manufactured in a GMP & FDA inspected facility

100% Pure

Pharmaceutical Grade Lab Tested for Potency

120 Servings

Vegetable Capsule

Made in a GMP & FDA inspected facility

Made in USA

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

General

51816-001 B20380-000

Seals/Symbols

OU

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Vitamin B-2 100 Milligrams by NutraBio label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Vitamin B-2 100 Milligrams label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Vitamin B-2 100 Milligrams by NutraBio

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size1 Vegetable Capsule(s) Dosage formCapsule Servings per container120 Amounts shown are per serving.

Riboflavin

Interacts with
20 drugs
100 mg per serving Form: Vitamin B2

Riboflavin (vitamin B2) is an essential nutrient your body needs to turn food into energy and to keep skin, eyes, and nerves healthy. It is generally...

Riboflavin monograph & interactions

Other (inactive) ingredients: Rice Flour, Vegetable Capsule. These complete the product’s ingredient list but are not active constituents.

Interaction report

Vitamin B-2 100 Milligrams by NutraBio Drug Interactions

Want to check YOUR meds against Vitamin B-2 100 Milligrams?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
20Drugs
20 Moderate

Ingredients driving the most interactions

Riboflavin 20

Individual Drug Interactions

The ingredients in Vitamin B-2 100 Milligrams interact with 20 drugs. Click any drug to see the details.

1 of the 1 ingredient in Vitamin B-2 100 Milligrams interact with drugs. Each result below shows which ingredient is responsible. Riboflavin

Each ingredient & the kinds of drugs it affects

For each ingredient in Vitamin B-2 100 Milligrams with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Riboflavin1 drug type · 20 drugs

Tetracycline Antibiotics

Theoretically, taking riboflavin with tetracycline antibiotics may decrease the potency of these antibiotics.
In vitro research suggests that riboflavin may inhibit the potency of tetracycline antibiotics. It is not clear if this effect is clinically significant, as this interaction has not been reported in humans.

Likelihood Possible Evidence D
Riboflavin full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Vitamin B-2 100 Milligrams, from the product label.

NutraBio

See all NutraBio products
Name
NutraBio Labs, Inc.
Street Address
564 Lincoln Blvd.
City
Middlesex
State
NJ
ZipCode
08846
Phone Number
732-748-8606
Web Address
www.nutrabio.com
Pharmacist Counseling Corner

Vitamin B-2 100 Milligrams by NutraBio: Common Questions

Does Vitamin B-2 100 Milligrams by NutraBio interact with any medications?
Yes. Based on its ingredients, Vitamin B-2 100 Milligrams has a known interaction with 20 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Vitamin B-2 100 Milligrams contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Will this supplement turn my urine yellow?
Yes — bright yellow urine is a normal, dose-related side effect of riboflavin supplements. It's harmless and happens because excess riboflavin leaves your body through urine. The color will return to normal once you stop taking it.
Is this safe if I'm pregnant or breastfeeding?
Riboflavin is needed during both pregnancy and breastfeeding and is considered safe at recommended amounts. Since this is a high-dose supplement (100 mg), talk with your doctor or pharmacist to confirm it's the right choice for you.
Can I take this with other medications?
The main concern is tetracycline antibiotics — this supplement may lower their effectiveness. Check with your doctor or pharmacist about your specific medications before you start.
What is riboflavin used for in the body?
Riboflavin (vitamin B-2) helps your body convert food into energy and supports cell growth and repair. It's an essential nutrient you need every day.
What are the most common side effects?
Nausea and bright yellow urine are the most common side effects at higher doses. Both are dose-related and harmless — the urine color returns to normal when you stop taking it.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Vitamin B-2 100 Milligrams is safe with your meds?

Our pharmacists answer your medication & supplement questions — free.

Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Vitamin B-2 100 Milligrams label
Go deeper

The Full Monographs Behind Vitamin B-2 100 Milligrams’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Riboflavin

Interacts with 20 drugs

Riboflavin (vitamin B2) is an essential nutrient your body needs to turn food into energy and to keep skin, eyes, and nerves healthy. It is generally very safe at typical doses, and the stro...

Read the full Riboflavin monograph →
Sources

Sources & How We Checked

Vitamin B-2 100 Milligrams's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 5 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Riboflavin 5 references
  1. Schoenen J, Jacquy J, Lenaerts M. Effectiveness of high-dose riboflavin in migraine prophylaxis. A randomized controlled trial. Neurology 1998;50:466-70. PubMed
  2. Yates AA, Schlicker SA, Suitor CW. Dietary reference intakes: The new basis for recommendations for calcium and related nutrients, B vitamins, and choline. J Am Diet Assoc 1998;98:699-706. PubMed
  3. Leeson LJ, Weidenheimer JF. Stability of tetracycline and riboflavin. J Pharm Sci. 1969;58(3):355-7. PubMed
  4. MacLennan, S. C., Wade, F. M., Forrest, K. M., Ratanayake, P. D., Fagan, E., and Antony, J. High-dose riboflavin for migraine prophylaxis in children: a double-blind, randomized, placebo-controlled trial. J Child Neurol. 2008;23(11):1300-1304.
  5. Dietary reference intakes (DRIs): estimated average requirements. Food and Nutrition Board, Institute of Medicine, National Academics. https://www.nal.usda.gov/sites/default/files/fnic_uploads//recommended_intakes_individuals.pdf Accessed July 24, 2017.

See these in context on the Riboflavin monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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