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Dietary supplement

Vitamin B-2 (Riboflavin) 100 mg Ingredients & Drug Interactions

by LuckyVitamin

Vitamin B-2 (Riboflavin) 100 mg label
See full label image
Capsule Category: Vitamin
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Oct 7, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Vitamin B-2 (Riboflavin) 100 mg against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Vitamin B-2 (Riboflavin) 100 mg is a dietary supplement by LuckyVitamin with 1 active ingredient. Its ingredients are commonly taken for riboflavin deficiency, migraine prevention, general energy and metabolism support.Based on those ingredients, 20 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Riboflavin. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

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Check Your Meds Against Vitamin B-2 (Riboflavin) 100 mg by LuckyVitamin

Ask about any prescription or over-the-counter medication and we check it for interactions with Vitamin B-2 (Riboflavin) 100 mg by LuckyVitamin — and tell you which ingredient is responsible.

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HelloPharmacist Scorecard of Vitamin B-2 (Riboflavin) 100 mg by LuckyVitamin

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Sep 24, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

This product contains one active ingredient: riboflavin (vitamin B-2) at 100 mg per capsule. Riboflavin is a B vitamin your body uses to convert food into energy and support cell health.

The capsule also contains inactive ingredients: rice flour, hypromellose, stearic acid, and silicon dioxide — these are fillers and binders that hold the capsule together.

Does it work?

Couldn't assess
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not assessable

We hold no graded evidence for this product's ingredients for its stated purpose.

Why this rating?
  • The label markets this product for: energy production.
  • Our graded evidence for these ingredients doesn't cover that particular purpose.

We hold no effectiveness ratings for riboflavin in our data, so we cannot speak to how well it works for any particular use. If you're considering it for a specific health goal, talk with your doctor or pharmacist about whether the evidence supports that use.

The evidence, ingredient by ingredient Riboflavin

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Riboflavin is generally well tolerated when taken by mouth. The main side effects are dose-related nausea and bright yellow urine — the urine color change is harmless and expected at higher doses.

A small number of people have reported diarrhea at very high doses (400 mg daily). Riboflavin is considered likely safe in pregnancy and breastfeeding at recommended amounts.

High-dose supplements during pregnancy or breastfeeding warrant a conversation with your provider first. Excess riboflavin your body doesn't need is simply removed in the urine, which is why toxicity from this vitamin is extremely rare.

Side effects, ingredient by ingredient Riboflavin

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Riboflavin.
  • The most serious interaction on file is rated Moderate.
  • For scale: 20 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

If you take tetracycline antibiotics (doxycycline, minocycline, tetracycline, or others in that class), double-check with your doctor or pharmacist before using this supplement — riboflavin may reduce their effectiveness. No other medication interactions are documented for the ingredients we could check.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with no assessable stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.

This is a straightforward, single-ingredient B-2 supplement that most people tolerate well. The main thing to watch for is tetracycline antibiotics — if you take one, confirm with your doctor or pharmacist before starting this product.

Pregnant or breastfeeding? Talk with your provider about whether high-dose riboflavin is right for you.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Mar 22, 2023.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Vitamin B-2 (Riboflavin) 100 mg, straight from the product label.

Brand LuckyVitamin
Barcode (UPC) 810026421204
Net contents 100 Veg Capsule(s)
Market status On market
Date entered into DSLD Mar 22, 2023
DSLD ID 283315
Product type Vitamin
Supplement form Capsule
Dietary claims / uses Nutrient, All Other, Structure/Function
Intended target group(s) Vegan, Vegetarian, Adult (18 - 50 Years), Gluten Free, Dairy Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Vitamin B-2 (Riboflavin) 100 mg by LuckyVitamin, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Veg Capsule(s)
Maximum serving Sizes:
1 Veg Capsule(s)
Servings per container
100
UPC/BARCODE
810026421204
IngredientAmount% DV
Riboflavin100 mg7692%

Other ingredients: Rice Flour, Hypromellose, Stearic Acid, Silicon Dioxide

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Suggested/Recommended/Usage/Directions

Suggested Usage: Take 1 capsule daily with a meal.

Formula

Vitamin B-2, also known as riboflavin, is a member of the B-vitamin family. It occurs naturally in green vegetables, liver, kidneys, wheat germ, milk, eggs, cheese and fish. Riboflavin is an important enzyme cofactor necessary for energy production from carbohydrate, fat, and protein. It is also needed for the regeneration of glutathione, which supports the body's natural defense mechanisms and detoxification systems.

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

Seals/Symbols

Guaranteed Quality & Potency

Formulation

Energy Production

Not manufactured with wheat, gluten, soy, milk, egg, fish, shellfish or tree nut ingredients.

Natural color variation may occur in this product.

Non-GMO

Vegan

FDA Statement of Identity

Dietary Supplement

Precautions

Not manufactured with wheat, gluten, soy, milk, egg, fish, shellfish or tree nut ingredients. Produced in a GMP facility that processes other ingredients containing these allergens.

Storage

Store in a cool, dry place after opening.

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Vitamin B-2 (Riboflavin) 100 mg by LuckyVitamin label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Vitamin B-2 (Riboflavin) 100 mg label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Vitamin B-2 (Riboflavin) 100 mg by LuckyVitamin

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size1 Veg Capsule(s) Dosage formCapsule Servings per container100 Amounts shown are per serving.

Riboflavin

Interacts with
20 drugs
100 mg per serving Form: Vitamin B2

Riboflavin (vitamin B2) is an essential nutrient your body needs to turn food into energy and to keep skin, eyes, and nerves healthy. It is generally...

Riboflavin monograph & interactions

Other (inactive) ingredients: Rice Flour, Hypromellose, Stearic Acid, Silicon Dioxide. These complete the product’s ingredient list but are not active constituents.

Interaction report

Vitamin B-2 (Riboflavin) 100 mg by LuckyVitamin Drug Interactions

Want to check YOUR meds against Vitamin B-2 (Riboflavin) 100 mg?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
20Drugs
20 Moderate

Ingredients driving the most interactions

Riboflavin 20

Individual Drug Interactions

The ingredients in Vitamin B-2 (Riboflavin) 100 mg interact with 20 drugs. Click any drug to see the details.

1 of the 1 ingredient in Vitamin B-2 (Riboflavin) 100 mg interact with drugs. Each result below shows which ingredient is responsible. Riboflavin

Each ingredient & the kinds of drugs it affects

For each ingredient in Vitamin B-2 (Riboflavin) 100 mg with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Riboflavin1 drug type · 20 drugs

Tetracycline Antibiotics

Theoretically, taking riboflavin with tetracycline antibiotics may decrease the potency of these antibiotics.
In vitro research suggests that riboflavin may inhibit the potency of tetracycline antibiotics. It is not clear if this effect is clinically significant, as this interaction has not been reported in humans.

Likelihood Possible Evidence D
Riboflavin full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Vitamin B-2 (Riboflavin) 100 mg, from the product label.

LuckyVitamin

See all LuckyVitamin products
Name
Lucky Health Group Inc.
City
Conshohocken
State
PA
ZipCode
19428
Phone Number
1-888-635-0474
Web Address
www.LuckyVitamin.com
Pharmacist Counseling Corner

Vitamin B-2 (Riboflavin) 100 mg by LuckyVitamin: Common Questions

Does Vitamin B-2 (Riboflavin) 100 mg by LuckyVitamin interact with any medications?
Yes. Based on its ingredients, Vitamin B-2 (Riboflavin) 100 mg has a known interaction with 20 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Vitamin B-2 (Riboflavin) 100 mg contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Will this turn my urine bright yellow?
Yes — at higher doses, riboflavin commonly causes bright yellow urine. This is harmless and simply means your body is excreting excess vitamin B-2. The color will return to normal once you stop taking it.
Is riboflavin safe to take while pregnant?
Riboflavin is considered likely safe during pregnancy at recommended doses, and it's actually needed for fetal development. High-dose supplements are a different story — check with your provider before taking amounts much higher than what you'd get from food.
Can I take this while breastfeeding?
Riboflavin is needed while breastfeeding and is generally safe at recommended amounts. If you're considering a high-dose supplement, ask your provider about what's right for you and your baby.
What are the side effects?
Most people tolerate riboflavin well. The most common side effect is dose-related nausea. At higher doses (like 400 mg daily), some people have reported diarrhea or increased urination. These are rare and generally mild.
Can my body overdose on riboflavin?
No — riboflavin is a water-soluble B vitamin, so excess amounts that your body doesn't need are simply filtered out in the urine. Toxicity from riboflavin is extremely rare.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Vitamin B-2 (Riboflavin) 100 mg is safe with your meds?

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Vitamin B-2 (Riboflavin) 100 mg label
Go deeper

The Full Monographs Behind Vitamin B-2 (Riboflavin) 100 mg’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Riboflavin

Interacts with 20 drugs

Riboflavin (vitamin B2) is an essential nutrient your body needs to turn food into energy and to keep skin, eyes, and nerves healthy. It is generally very safe at typical doses, and the stro...

Read the full Riboflavin monograph →
Sources

Sources & How We Checked

Vitamin B-2 (Riboflavin) 100 mg's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 5 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Riboflavin 5 references
  1. Schoenen J, Jacquy J, Lenaerts M. Effectiveness of high-dose riboflavin in migraine prophylaxis. A randomized controlled trial. Neurology 1998;50:466-70. PubMed
  2. Yates AA, Schlicker SA, Suitor CW. Dietary reference intakes: The new basis for recommendations for calcium and related nutrients, B vitamins, and choline. J Am Diet Assoc 1998;98:699-706. PubMed
  3. Leeson LJ, Weidenheimer JF. Stability of tetracycline and riboflavin. J Pharm Sci. 1969;58(3):355-7. PubMed
  4. MacLennan, S. C., Wade, F. M., Forrest, K. M., Ratanayake, P. D., Fagan, E., and Antony, J. High-dose riboflavin for migraine prophylaxis in children: a double-blind, randomized, placebo-controlled trial. J Child Neurol. 2008;23(11):1300-1304.
  5. Dietary reference intakes (DRIs): estimated average requirements. Food and Nutrition Board, Institute of Medicine, National Academics. https://www.nal.usda.gov/sites/default/files/fnic_uploads//recommended_intakes_individuals.pdf Accessed July 24, 2017.

See these in context on the Riboflavin monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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