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Dietary supplement

Vitamin B12 2500 Black Cherry Flavored Ingredients & Drug Interactions

by Vinco's

Tablet Or Pill Category: Vitamin
Most serious interaction: Minor
The interaction bottom line Most serious interaction: Minor

Vitamin B12 2500 Black Cherry Flavored is a dietary supplement by Vinco's with 1 active ingredient. Its ingredients are commonly taken for treating or preventing b12 deficiency, pernicious anemia, low energy and fatigue.Based on those ingredients, 20 medications have a known interaction with it, the most serious rated minor. The ingredients most likely to interact are Vitamin B12. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

HelloPharmacist Scorecard of Vitamin B12 2500 Black Cherry Flavored by Vinco's

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

This product contains a single active ingredient: Vitamin B12, a B-complex vitamin your body needs to make red blood cells and maintain healthy nerve function. The tablet also contains inactive ingredients like mannitol (a sweetener) and crospovidone (a binder) that help form and flavor the pill.

Does it work?

Strong evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Strong

Clinical evidence supports at least one of this product's ingredients for its stated purpose.

Why this rating?
  • The label markets this product for: improved energy, focus, memory and mood.
  • We looked for evidence on: Age-related cognitive decline, Attention, Cognitive function, Cognitive impairment, Dementia, Depression — and 4 related terms.
  • The strongest evidence on file: Vitamin B12 is rated "Effective" for Vitamin B12 deficiency (Natural Medicines).
  • Also on file: Vitamin B12 is rated "Possibly Ineffective" for Age-related cognitive decline, Cognitive impairment.
  • Also on file: Vitamin B12 is rated "Insufficient Reliable Evidence To Rate" for Chemotherapy-induced peripheral neuropathy, Cognitive function, Dementia, Depression.

Vitamin B12 is effective for treating B12 deficiency and Imerslund-Grasbeck disease (a rare inherited condition affecting B12 absorption). It's also likely effective for cyanide poisoning.

The evidence supports its use as possibly effective for canker sores and postherpetic neuralgia (nerve pain following shingles), though these uses are less well established.

The evidence, ingredient by ingredient Vitamin B12

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Vitamin B12 is generally very well tolerated when taken by mouth — your body clears excess through your urine, so there's no established upper limit. The most common side effects are rare and mild; allergic reactions like rash or itching can occur, particularly in people with a cobalt allergy, since B12 contains cobalt.

In very rare cases, correcting severe B12 deficiency (megaloblastic anemia) has been linked to a dangerous drop in potassium (hypokalemia), though this is extremely uncommon. B12 is needed during pregnancy and breastfeeding and is considered safe at normal recommended doses — follow your provider's guidance on how much you need.

Side effects, ingredient by ingredient Vitamin B12

Meds to double-check

Minor interactions only
Known Interaction Concern · database check
Minor only

Only Minor-severity interactions are documented for these ingredients.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Vitamin B12.
  • The most serious interaction on file is rated Minor.
  • For scale: 20 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

If you take metformin (Glucophage) for diabetes, let your pharmacist know — B12 can help offset the B12 lowering effect of that drug, which is actually why this combination is common. No other major interactions are documented for the ingredients we could check, but always verify your exact medications with the tool on this page.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with clinical evidence supporting its stated purpose. Only minor medication interactions are documented, and safety information is well characterized.

This is a straightforward B12 supplement for people with a B12 deficiency or those at risk of one, especially if they take metformin. If you're on any regular medications, check them with your pharmacist first — metformin users in particular may actually benefit from this supplement.

It's generally very safe and well tolerated.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Jun 25, 2014.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Vitamin B12 2500 Black Cherry Flavored, straight from the product label.

Brand Vinco's
Barcode (UPC) 739930275492
Net contents 60 Sublingual Tablet(s)
Market status On market
Date entered into DSLD Jun 25, 2014
DSLD ID 34010
Product type Vitamin
Supplement form Tablet Or Pill
Dietary claims / uses Nutrient, All Other, Structure/Function
Intended target group(s) Children 4 or More Years of Age, Adult (18 - 50 Years), Gluten Free, Dairy Free, Sugar Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Vitamin B12 2500 Black Cherry Flavored by Vinco's, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Sublingual Tablet(s)
Maximum serving Sizes:
1 Sublingual Tablet(s)
Servings per container
60
UPC/BARCODE
739930275492
IngredientAmount% DV
Vitamin B122500 mcg41667%

Other ingredients: Mannitol, Crospovidone, Natural flavor, Contains <2% of:

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
General

Item# V-B12

Suggested/Recommended/Usage/Directions

Directions for Use: For adults and children twelve or more years of age, take one sublingual tablet daily or as directed by a qualified healthcare professional. Let tablet dissolve in mouth or under tongue. Do not swallow whole.

General Statements

Vinco's Vitamin B12 2500 delivers a high dose of Vitamin B12 in a great tasting tablet that is dissolved sublingually for maximum absorption. Vitamin B12 has been shown to be beneficial in improved energy, focus, memory and mood.

PROFESSIONAL FORMULATION

Sublinqual

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

Storage

Storage: Keep tightly closed in a dry place; do not expose to excessive heat.

Precautions

KEEP OUT OF REACH OF CHILDREN

Tamper resistant. Do not purchase if seal if broken.

Formulation

Gluten Free

This product contains NO sugar, starch, milk, lactose, soy, gluten, yeast, fish, artificial flavor, or preservatives. Sodium Free

FDA Statement of Identity

Dietary Supplement

See for yourself

Vitamin B12 2500 Black Cherry Flavored by Vinco's label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

What’s inside

The Ingredients in Vitamin B12 2500 Black Cherry Flavored by Vinco's

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size1 Sublingual Tablet(s) Dosage formTablet Or Pill Servings per container60 Amounts shown are per serving.

Vitamin B12

Interacts with
20 drugs
2500 mcg per serving Form: Cyanocobalamin

Vitamin B12 (cobalamin) is an essential nutrient your body needs to make red blood cells, keep nerves healthy, and support DNA. Supplements are very h...

Vitamin B12 monograph & interactions

Other (inactive) ingredients: Mannitol, Crospovidone, Natural flavor, Contains <2% of:. These complete the product’s ingredient list but are not active constituents.

Interaction report

Vitamin B12 2500 Black Cherry Flavored by Vinco's Drug Interactions

Want to check YOUR meds against Vitamin B12 2500 Black Cherry Flavored?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

Go to the checker
20Drugs
20 Minor

Ingredients driving the most interactions

Each ingredient & the kinds of drugs it affects

For each ingredient in Vitamin B12 2500 Black Cherry Flavored with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Vitamin B121 drug type · 20 drugs

Metformin (Glucophage)

Metformin, a common medication used to manage type 2 diabetes, has been associated with lower vitamin B12 levels in some individuals. Prolonged use of metformin can interfere with the absorption of B12 in the digestive system, potentially leading to a deficiency in this essential vitamin.

Likelihood Possible Evidence A
The maker

Brand information

Manufacturer and brand details for Vitamin B12 2500 Black Cherry Flavored, from the product label.

Vinco's

See all Vinco's products
Name
vinco Inc.
Phone Number
1-800-245-1939
Web Address
www.vincoinc.com
Pharmacist Counseling Corner

Vitamin B12 2500 Black Cherry Flavored by Vinco's: Common Questions

Does Vitamin B12 2500 Black Cherry Flavored by Vinco's interact with any medications?
Yes. Based on its ingredients, Vitamin B12 2500 Black Cherry Flavored has a known interaction with 20 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Vitamin B12 2500 Black Cherry Flavored contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Can I take this if I'm pregnant or breastfeeding?
Yes. B12 is needed during pregnancy and breastfeeding and is considered safe at normal recommended amounts. Follow your provider's guidance on how much you need.
I take metformin for diabetes — is this safe to use together?
Yes, it's actually a helpful combination. Metformin can lower your B12 levels over time, so supplementing can help prevent a deficiency. Talk to your doctor or pharmacist about the right dose for you.
What are the side effects?
B12 taken by mouth is generally very well tolerated. Serious side effects are rare. Allergic reactions like rash or itching can happen, especially if you have a cobalt allergy — the vitamin contains cobalt. In extremely rare cases, correcting a severe B12 deficiency has been linked to a dangerous drop in potassium, but this is very uncommon.
Is there an upper limit — can I take too much?
No established upper limit exists for B12 because excess is removed through your urine. Your body uses what it needs and clears the rest, so overdose isn't a practical concern with oral supplements.
Does this work for canker sores and nerve pain?
The evidence supports B12 as possibly effective for canker sores and postherpetic neuralgia (nerve pain after shingles), though these uses are less well established than its role in treating B12 deficiency.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Vitamin B12 2500 Black Cherry Flavored is safe with your meds?

Our pharmacists answer your medication & supplement questions — free.

Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Vitamin B12 2500 Black Cherry Flavored label
Go deeper

The Full Monographs Behind Vitamin B12 2500 Black Cherry Flavored’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Sources

Sources & How We Checked

Vitamin B12 2500 Black Cherry Flavored's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 30 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Vitamin B12 30 references
  1. Food and Nutrition Board, Institute of Medicine. Dietary Reference Intakes for Thiamin, Riboflavin, Niacin, Vitamin B6, Folate, Vitamin B12, Pantothenic Acid, Biotin, and Choline (2000). Washington, DC: National Academy Press, 2000. Available at: http://b
  2. Hartman TJ, Woodson K, Stolzenberg-Solomon R, et al. Association of the B-vitamins pyridoxal 5'-phosphate (B6), B12, and folate with lung cancer risk in older men. Am J Epidemiol 2001;153:688-94.. DOI
  3. Jansen T, Romiti R, Kreuter A, Altmeyer P. Rosacea fulminans triggered by high-dose vitamins B6 and B12. J Eur Acad Dermatol Venereol 2001;15:484-5..
  4. Lange H, Suryapranata H, De Luca G, et al. Folate therapy and in-stent restenosis after coronary stenting. N Engl J Med 2004;350:2673-81. PubMed
  5. Collin, S. M., Metcalfe, C., Refsum, H., Lewis, S. J., Zuccolo, L., Smith, G. D., Chen, L., Harris, R., Davis, M., Marsden, G., Johnston, C., Lane, J. A., Ebbing, M., Bonaa, K. H., Nygard, O., Ueland, P. M., Grau, M. V., Baron, J. A., Donovan, J. L., Nea
  6. Geissbuhler, P., Mermillod, B., and Rapin, C. H. Elevated serum vitamin B12 levels associated with CRP as a predictive factor of mortality in palliative care cancer patients: a prospective study over five years. J.Pain Symptom.Manage. 2000;20(2):93-103. PubMed
  7. Salles, N., Herrmann, F., Sakbani, K., Rapin, C. H., and Sieber, C. High vitamin B12 level: a strong predictor of mortality in elderly inpatients. J Am Geriatr.Soc 2005;53(5):917-918.
  8. Looker, H. C., Fagot-Campagna, A., Gunter, E. W., Pfeiffer, C. M., Sievers, M. L., Bennett, P. H., Nelson, R. G., Hanson, R. L., and Knowler, W. C. Homocysteine and vitamin B(12) concentrations and mortality rates in type 2 diabetes. Diabetes Metab Res R
  9. Uhl, W., Nolting, A., Golor, G., Rost, K. L., and Kovar, A. Safety of hydroxocobalamin in healthy volunteers in a randomized, placebo-controlled study. Clin Toxicol (Phila) 2006;44 Suppl 1:17-28. PubMed
  10. Borron, S. W., Baud, F. J., Barriot, P., Imbert, M., and Bismuth, C. Prospective study of hydroxocobalamin for acute cyanide poisoning in smoke inhalation. Ann Emerg.Med 2007;49(6):794-801, 801. PubMed
  11. Borron, S. W., Baud, F. J., Megarbane, B., and Bismuth, C. Hydroxocobalamin for severe acute cyanide poisoning by ingestion or inhalation. Am J Emerg.Med 2007;25(5):551-558. PubMed
  12. Lewis, J. G. Gout, Steatorrhoea, and Megaloblastic Anaemia. Ann Rheum.Dis 1962;21(3):284-286. PubMed
  13. Tal, S., Shavit, Y., Stern, F., and Malnick, S. Association between vitamin B12 levels and mortality in hospitalized older adults. J Am Geriatr.Soc 2010;58(3):523-526. PubMed
  14. Baztan, J. J., Gavidia, J. J., Gomez-Pavon, J., Esteve, A., and Ruiperez, I. High vitamin B12 levels and in-hospital mortality. J Am Geriatr.Soc 2010;58(11):2237-2238. PubMed
  15. Omboni, E., Checchini, M., and Longoni, F. [Hypopotassemia and megaloblastic anemia. Presentation of a case]. Minerva Med 8-31-1987;78(16):1255-1257.
  16. Aalfs As, Scholvinck LH, Horvath B. Acneiform eruption in a 5-year old due to vitamin B12 supplementation. Eur J Dermatol 2013;23(5):726-7. PubMed
  17. Balta I, Ozuguz P. Vitamin B12-induced acneiform eruption. Cutan Ocul Toxicol 2014;33(2):94-5. PubMed
  18. Carman KB, Belgemen T, Yis U. Involuntary movements misdiagnosed as seizure during vitamin B12 treatment. Pediatr Emerg Care 2013;29(11):1223-4. PubMed
  19. Djuric V, Bogic M, Popadic AP, et al. Anaphylactic reaction to hydroxycobalamin with tolerance to cyanocobalamin. Ann Allergy Asthma Immunol 2012;108(3):207-8. PubMed
  20. Kartel O, Gulec M, Demirel F, et al. Vitamin B12 allergy and successful desensitization with cyanocobalamin: A case report. Allergol Immunopath (Madr) 2012;40(5):324-5.
  21. Patiroglu T, Unal E, Yildirim S. Infantile tremor syndrome associated with cobalamin therapy: A case report. Clin Neurol Neurosurg 2013;115(9):1903-5. PubMed
  22. Schulte S, Barkema LW, Kardaun SH. Long-lasting atypical acneiform eruption with prominent comedones induced by hydroxocobalamin (vitamin B12). J Dtsch Dermatol Ges 2014;12(6):502-3.
  23. Zanus C, Alberini E, Costa P, et al. Involuntary movements after correction of vitamin B12 deficiency: A video-case report. Epileptic Disord 2012;14(2):174-80. PubMed
  24. Fanidi A, Carreras-Torres R, Larose TL, et al. Is high vitamin B12 status a cause of lung cancer? Int J Cancer. 2019 Sep 15;145(6):1499-1503. PubMed
  25. Fujita Y, Mizukami T, Maya Y, et al. Vitamin B12 allergy manifesting as lymphomatoid contact dermatitis. Eur J Dermatol. 2020;30(3):304-305. PubMed
  26. Dépret F, Hoffmann C, Daoud L, et al. Association between hydroxocobalamin administration and acute kidney injury after smoke inhalation: a multicenter retrospective study. Crit Care. 2019;23(1):421. PubMed
  27. Khairan P, Sobue T, Eshak ES, et al. Association of dietary intakes of vitamin B12, vitamin B6, folate, and methionine with the risk of esophageal cancer: the Japan Public Health Center-based (JPHC) prospective study. BMC Cancer 2021;21(1):982. PubMed
  28. Evans J, Pandya A, Ding Y, Qunibi WY. Hydroxocobalamin-Induced Oxalate Nephropathy in a Patient With Smoke Inhalation. Kidney Int Rep 2021;6(8):2228-2231. PubMed
  29. Lacombe V, Chabrun F, Lacout C, et al. Persistent elevation of plasma vitamin B12 is strongly associated with solid cancer. Sci Rep 2021;11(1):13361. PubMed
  30. Pegalajar-García MD, Cebolla-Verdugo M, Prados-Carmona Á, Llamas-Segura C, Navarro-Triviño FJ. Systemic allergic dermatitis to cobalt present in cyanocobalamin supplementation. Contact Dermatitis 2023;89(3):203-205. PubMed

See these in context on the Vitamin B12 monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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