Interactions on record — worth a quick check against your medications. Check your meds →
Dietary supplement

Wild Cherry Bark Ingredients & Drug Interactions

by Pure Herbs

Wild Cherry Bark label
See full label image
Liquid Category: Botanical
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 23, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Wild Cherry Bark against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Wild Cherry Bark is a dietary supplement by Pure Herbs with 1 active ingredient. Its ingredients are commonly taken for cough, bronchitis and respiratory irritation, sore throat.Based on those ingredients, 643 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Black Cherry Bark Extract. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

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Check Your Meds Against Wild Cherry Bark by Pure Herbs

Ask about any prescription or over-the-counter medication and we check it for interactions with Wild Cherry Bark by Pure Herbs — and tell you which ingredient is responsible.

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HelloPharmacist Scorecard of Wild Cherry Bark by Pure Herbs

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Sep 24, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

Pure Herbs Wild Cherry Bark is a single-ingredient liquid containing black cherry bark extract. Wild cherry has been used traditionally in cough remedies and throat lozenges for generations.

This product contains one active ingredient, so there's no blend to sort through—you're getting black cherry bark and nothing else as an active component.

Does it work?

Couldn't assess
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not assessable

We hold no graded evidence for this product's ingredients for its stated purpose.

Why this rating?
  • The label markets this product for: supports healthy respiratory system.
  • We looked for evidence on: cough, bronchitis, respiratory irritation.
  • Our graded evidence for these ingredients doesn't cover that particular purpose.

We don't have effectiveness ratings on file for wild cherry bark. The evidence base we hold doesn't establish whether it works for cough, sore throat, or any other condition.

If you're considering it for a specific purpose, talk it over with your pharmacist or doctor about what the broader research shows.

The evidence, ingredient by ingredient Wild Cherry

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Wild cherry bark is generally well tolerated in the small amounts found in commercial cough products. However, it contains compounds that can produce cyanide when broken down in your body, so large amounts are dangerous.

In one documented case, a person who steeped about 300 grams of wild cherries in alcohol developed severe poisoning with headache, nausea, vomiting, confusion, breathing difficulty, and loss of consciousness—so overdose is a real risk. The safety data advises against use during pregnancy because the evidence suggests it may be unsafe.

There isn't enough safety information to use it while breastfeeding, so talk with your doctor or pharmacist about whether it's right for you in that situation. Stick to small, recommended doses and never exceed what the label suggests.

Side effects, ingredient by ingredient Wild Cherry

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Wild Cherry.
  • The most serious interaction on file is rated Moderate.
  • For scale: 644 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

If you take any medication metabolized by the CYP3A4 enzyme—including certain cholesterol drugs, antifungal medications, and many others—you'll want to check the interaction before using this product. The interaction is documented as Moderate in lab studies, though it hasn't been confirmed in patients yet.

Use the search tool on this page to verify your exact medications.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with no assessable stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.

Wild cherry bark may be worth considering if you're looking for a traditional throat or cough remedy, but only in the small doses found in standard products. Because of the theoretical enzyme interaction and the cyanide risk at high doses, it's not something to use on your own without guidance.

Check your medications against this page, and talk with your doctor or pharmacist before starting—especially if you're pregnant, breastfeeding, or taking drugs metabolized by CYP3A4.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Dec 13, 2022.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Wild Cherry Bark, straight from the product label.

Brand Pure Herbs
Net contents 1 Fluid Ounce(s); 30 mL
Market status On market
Date entered into DSLD Dec 13, 2022
DSLD ID 278883
Product type Botanical
Supplement form Liquid
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years), Women (not pregnant or lactating)
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Wild Cherry Bark by Pure Herbs, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
2 mL
Maximum serving Sizes:
2 mL
Servings per container
15
IngredientAmount% DV
Black Cherry Bark Extract1862 mg--

Other ingredients: None

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Suggested/Recommended/Usage/Directions

Directions: For adults, mix 2 mL (abt. 1/2 tsp) of extract in 2 fl. oz (60 mL) water one time daily preferably with a meal.

Shake well before use

Formulation

Supports a healthy respiratory system.

FDA Disclaimer Statement

This statement has not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

Precautions

Warning: Not intended for use by pregnant or nursing women. If you have a medical condition or are taking medication, consult your doctor prior to use.

Discontinue use and consult with your doctor if any adverse reactions occur.

Keep out of reach of children

Brand IP Statement(s)

Pure Herbs, Ltd. Natural Herbal Extracts

FDA Statement of Identity

Dietary Supplement

General Statements

"No expense has been spared to provide the finest nature has to offer."

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Wild Cherry Bark by Pure Herbs label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Wild Cherry Bark label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Wild Cherry Bark by Pure Herbs

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size2 mL Dosage formLiquid Servings per container15 Amounts shown are per serving.

Black Cherry Bark Extract

Interacts with
643 drugs
1862 mg per serving

Wild cherry bark is a traditional cough remedy found in many old-fashioned cough syrups and lozenges, but there is little modern scientific evidence p...

Black Cherry Bark Extract monograph & interactions

Other (inactive) ingredients: None. These complete the product’s ingredient list but are not active constituents.

Interaction report

Wild Cherry Bark by Pure Herbs Drug Interactions

Want to check YOUR meds against Wild Cherry Bark?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
643Drugs
643 Moderate

Ingredients driving the most interactions

Black Cherry Bark Extract 643

Individual Drug Interactions

The ingredients in Wild Cherry Bark interact with 643 drugs. Click any drug to see the details.

1 of the 1 ingredient in Wild Cherry Bark interact with drugs. Each result below shows which ingredient is responsible. Black Cherry Bark Extract

Each ingredient & the kinds of drugs it affects

For each ingredient in Wild Cherry Bark with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Black Cherry Bark Extract1 drug type · 643 drugs

Cytochrome P450 3A4 (Cyp3A4) Substrates

In vitro research suggests that wild cherry can inhibit cytochrome P450 3A4 (CYP3A4) enzymes. Theoretically, wild cherry might increase levels of drugs metabolized by CYP3A4. However, so far, this interaction has not been reported in humans.
Some drugs metabolized by CYP3A4 include lovastatin (Mevacor), ketoconazole (Nizoral), itraconazole (Sporanox), fexofenadine (Allegra), triazolam (Halcion), and others.

Likelihood Possible Evidence D
Black Cherry Bark Extract full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Wild Cherry Bark, from the product label.

Pure Herbs

See all Pure Herbs products
Name
Pure Herbs, Ltd.
City
Sterling Heights
State
MI
Phone Number
(800) 860-4372
Web Address
www.pureherbs.com
Pharmacist Counseling Corner

Wild Cherry Bark by Pure Herbs: Common Questions

Does Wild Cherry Bark by Pure Herbs interact with any medications?
Yes. Based on its ingredients, Wild Cherry Bark has a known interaction with 643 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Wild Cherry Bark contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Can I take this while I'm pregnant?
No. The safety data advises against use during pregnancy. Talk with your doctor before considering wild cherry bark if you're pregnant or planning to become pregnant.
Is it safe to breastfeed while taking this?
There isn't enough safety information to know either way. Because of that gap and the cyanide-forming compounds in wild cherry, it's safest to avoid it while breastfeeding. Check with your doctor or pharmacist for personalized advice.
What happens if I take too much?
Large amounts of wild cherry can cause cyanide toxicity, which can be serious or even fatal. Symptoms include headache, nausea, vomiting, confusion, and breathing difficulty. Stick to the dose on the label and never exceed it.
Does this product actually work for cough?
We don't have effectiveness data on file for wild cherry bark. It's been used traditionally in cough products for a long time, but we can't confirm from our data whether it's proven to work. Ask your pharmacist what the broader research shows.
Why does this interact with so many medications?
Wild cherry can slow down an enzyme your liver uses to break down a wide range of drugs. That enzyme handles metabolism for hundreds of medications across many categories—statins, antifungals, blood pressure drugs, and others—which is why the interaction list is so large. That doesn't mean all of them will be a problem for you; your pharmacist can check your specific medications.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Wild Cherry Bark is safe with your meds?

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Wild Cherry Bark label
Go deeper

The Full Monographs Behind Wild Cherry Bark’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Wild Cherry

Interacts with 643 drugs

Wild cherry bark is a traditional cough remedy found in many old-fashioned cough syrups and lozenges, but there is little modern scientific evidence proving it works. The bark, leaves, and s...

Read the full Wild Cherry monograph →
Sources

Sources & How We Checked

Wild Cherry Bark's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 4 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Wild Cherry 4 references
  1. Gruenwald J, Brendler T, Jaenicke C. PDR for Herbal Medicines. 1st ed. Montvale, NJ: Medical Economics Company, Inc., 1998.
  2. Brinker F. Herb Contraindications and Drug Interactions. 2nd ed. Sandy, OR: Eclectic Medical Publications, 1998.
  3. Budzinski JW, Foster BC, Vandenhoek S, Arnason JT. An in vitro evaluation of human cytochrome P450 3A4 inhibition by selected commercial herbal extracts and tinctures. Phytomedicine 2000;7:273-82. PubMed
  4. Pentore, R., Venneri, A., and Nichelli, P. Accidental choke-cherry poisoning: early symptoms and neurological sequelae of an unusual case of cyanide intoxication. Ital.J Neurol.Sci. 1996;17(3):233-235. PubMed

See these in context on the Wild Cherry monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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