Interactions on record — worth a quick check against your medications. Based on 1 of 3 ingredients. Check your meds →
Dietary supplement

Wild Oregano Oil Ingredients & Drug Interactions

by California Natural

Wild Oregano Oil label
See full label image
Liquid Category: Botanical
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 23, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Wild Oregano Oil against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Wild Oregano Oil is a dietary supplement by California Natural with 3 active ingredients. Its ingredients are commonly taken for digestive upset, respiratory and cold symptoms, antimicrobial support.Based on those ingredients, 208 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Oregano Oil. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

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Check Your Meds Against Wild Oregano Oil by California Natural

Ask about any prescription or over-the-counter medication and we check it for interactions with Wild Oregano Oil by California Natural — and tell you which ingredient is responsible.

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HelloPharmacist Scorecard of Wild Oregano Oil by California Natural

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Jul 11, 2026

What’s inside

Partial disclosure
Ingredient Transparency · database check
Partial

Most active ingredients list an amount, but at least one is hidden in a blend or missing.

Why this rating?
  • The label discloses an exact amount for 2 of its 3 active ingredients.

This product contains 3 active ingredients: oregano oil and wild Mediterranean oregano oil — both concentrated extracts of the oregano plant — plus carvacrol, a compound found in oregano. These are delivered in liquid form.

There are no inactive ingredients listed.

Does it work?

Couldn't assess
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not assessable

This is a single-ingredient Oregano product and its label doesn't state a use — see Oregano's own graded uses on its monograph.

Why this rating?
  • We looked at the product name, claims, and label statements and couldn't find a stated purpose to grade.

The evidence for oregano oil isn't established in our data. We rate its effectiveness for acne, bronchitis, asthma, headache, and upper respiratory tract infection all as insufficient reliable evidence to rate — meaning the studies we hold don't show it works for these uses, but that doesn't mean it doesn't; it just means we don't have solid proof yet.

The evidence, ingredient by ingredient Oregano

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

When you use oregano in normal food amounts, it's well tolerated. But this is a concentrated supplement, which is stronger and less studied than food-level doses.

The most common side effect is gastrointestinal upset. Topical use can cause skin irritation or dermatitis, especially in sensitive people or if the oil concentration is above 1%.

Rare but serious allergic reactions, including anaphylaxis, have been reported — one case involved severe swelling, breathing difficulty, and low blood pressure after eating oregano-seasoned food in someone with Lamiaceae plant sensitivity. During pregnancy, avoid medicinal or supplement amounts of oregano — food amounts are likely fine.

While breastfeeding, stick to normal food amounts; we don't have enough safety data for supplements at this dose.

Side effects, ingredient by ingredient Oregano

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Oregano.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: anticoagulant / antiplatelet drugs; diabetes medications.
  • For scale: 208 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before taking this product, double-check with your pharmacist if you're on blood thinners (anticoagulants) like warfarin or antiplatelet drugs like aspirin or clopidogrel — oregano oil may increase bleeding risk. Also verify if you take diabetes medications, since oregano might lower blood sugar and raise your risk of going too low.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glancePartially disclosed formula with no assessable stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.

Oregano oil supplement may appeal to people looking for traditional herbal support, but it's worth a careful medication check first — particularly if you take blood thinners or diabetes drugs. If you have a known oregano or plant-family allergy, talk with your pharmacist before trying this.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 3 of 3 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Jul 27, 2021.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Wild Oregano Oil, straight from the product label.

Brand California Natural
Net contents 1 fl. Oz.; 30 mL
Market status On market
Date entered into DSLD Jul 27, 2021
DSLD ID 247941
Product type Botanical
Supplement form Liquid
Dietary claims / uses All Other
Intended target group(s) Vegetarian, Adult (18 - 50 Years)
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Wild Oregano Oil by California Natural, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
108 mg
Maximum serving Sizes:
108 mg
Servings per container
270
IngredientAmount% DV
Oregano Oil43 mg--
Carvacrol30 mg--
Wild Mediterranean Oregano Oil0 NP--

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Formulation

100% Vegetarian

Herbal Supplement

Formula

70% Carvacrol

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Wild Oregano Oil by California Natural label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Wild Oregano Oil label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Wild Oregano Oil by California Natural

These are the 3 active ingredients this product is made of. Select any to open its full monograph.

Serving size108 mg Dosage formLiquid Servings per container270 Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

Oregano Oil

Interacts with
208 drugs
43 mg per serving

Oregano is a common Mediterranean cooking herb that is also sold as a concentrated oil or supplement, often standardized for a compound called carvacr...

Oregano Oil monograph & interactions

Carvacrol

Interacts with
208 drugs
30 mg per serving

Oregano is a common Mediterranean cooking herb that is also sold as a concentrated oil or supplement, often standardized for a compound called carvacr...

Carvacrol monograph & interactions

Wild Mediterranean Oregano Oil

Interacts with
208 drugs
0 NP per serving Form: Carvacrol

Oregano is a common Mediterranean cooking herb that is also sold as a concentrated oil or supplement, often standardized for a compound called carvacr...

Wild Mediterranean Oregano Oil monograph & interactions
Interaction report

Wild Oregano Oil by California Natural Drug Interactions

Want to check YOUR meds against Wild Oregano Oil?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
208Drugs
208 Moderate

Ingredients driving the most interactions

Oregano Oil 208

Individual Drug Interactions

The ingredients in Wild Oregano Oil interact with 208 drugs. Click any drug to see the details.

1 of the 3 ingredients in Wild Oregano Oil interact with drugs. Each result below shows which ingredient is responsible. Oregano Oil

Each ingredient & the kinds of drugs it affects

For each ingredient in Wild Oregano Oil with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Oregano Oil2 drug types · 208 drugs

Anticoagulant/Antiplatelet Drugs

Theoretically, oregano might increase the risk of bleeding when taken with anticoagulant or antiplatelet drugs.
In vitro research shows that aristolochic acid isolated from oregano leaves has antithrombin activity. It has also been reported that oregano oil inhibits arachidonic acid-induced, and ADP-induced, platelet aggregation.

Likelihood Possible Evidence D
Antidiabetes Drugs

Theoretically, oregano might increase the risk for hypoglycemia when taken with antidiabetes drugs.
In vitro and animal research shows that oregano extracts might lower blood glucose levels.

Likelihood Possible Evidence D
Oregano Oil full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Wild Oregano Oil, from the product label.

California Natural

See all California Natural products
Name
California Natural
Pharmacist Counseling Corner

Wild Oregano Oil by California Natural: Common Questions

Does Wild Oregano Oil by California Natural interact with any medications?
Yes. Based on its ingredients, Wild Oregano Oil has a known interaction with 208 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Wild Oregano Oil contains 3 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
What's actually in this product?
California Natural's Wild Oregano Oil is a liquid with three active ingredients: oregano oil, wild Mediterranean oregano oil, and carvacrol — all forms of concentrated oregano plant extract. There are no fillers or other inactive ingredients.
Does oregano oil actually work for colds or respiratory infections?
The evidence isn't established in our data. We don't have reliable studies showing it works for upper respiratory infections, bronchitis, or asthma, so we can't rate it one way or the other.
Is it safe to use while I'm pregnant or breastfeeding?
During pregnancy, avoid supplement amounts — food amounts of oregano are likely fine. While breastfeeding, stick to normal food amounts; we don't have enough safety data to know if supplements at this strength are okay. Talk with your doctor or pharmacist for personalized advice.
What side effects might I notice?
The most common is stomach upset when taken by mouth. If you apply it topically, it can cause skin irritation or dermatitis, especially in sensitive skin. Serious allergic reactions including anaphylaxis are rare but have been reported, mostly in people with sensitivity to oregano or related plants.
Can I take this if I have a plant allergy?
If you're allergic to oregano or other plants in the Lamiaceae family (like thyme, basil, and rosemary), talk with your pharmacist first. At least one case involved a severe allergic reaction in someone sensitive to this plant family.
How much stronger is this supplement compared to cooking with oregano?
This is a concentrated liquid extract — much stronger than the dried oregano you'd sprinkle on pizza. While food amounts of oregano are well tolerated, these concentrated supplements are less studied and carry more caution, especially for bleeding and blood sugar risks.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Wild Oregano Oil is safe with your meds?

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Wild Oregano Oil label
Go deeper

The Full Monographs Behind Wild Oregano Oil’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Oregano

Interacts with 208 drugs

Oregano is a common Mediterranean cooking herb that is also sold as a concentrated oil or supplement, often standardized for a compound called carvacrol. While lab studies suggest it may hav...

Read the full Oregano monograph →
Sources

Sources & How We Checked

Wild Oregano Oil's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 12 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Oregano 12 references
  1. Brinker F. Herb Contraindications and Drug Interactions. 2nd ed. Sandy, OR: Eclectic Medical Publications, 1998.
  2. Benito M, Jorro G, Morales C, et al. Labiatae allergy: systemic reactions due to ingestion of oregano and thyme. Ann Allergy Asthma Immunol 1996;76:416-8. PubMed
  3. Chevallier A. Encyclopedia of Herbal Medicine. 2nd ed. New York, NY: DK Publ, Inc., 2000.
  4. Ciganda C, and Laborde A. Herbal infusions used for induced abortion. J Toxicol.Clin Toxicol. 2003;41:235-239. PubMed
  5. Futrell, J. M. and Rietschel, R. L. Spice allergy evaluated by results of patch tests. Cutis 1993;52(5):288-290.
  6. Tognolini, M., Barocelli, E., Ballabeni, V., Bruni, R., Bianchi, A., Chiavarini, M., and Impicciatore, M. Comparative screening of plant essential oils: phenylpropanoid moiety as basic core for antiplatelet activity. Life Sci. 2-23-2006;78(13):1419-1432. PubMed
  7. Goun, E., Cunningham, G., Solodnikov, S., Krasnykch, O., and Miles, H. Antithrombin activity of some constituents from Origanum vulgare. Fitoterapia 2002;73(7-8):692-694. PubMed
  8. Lemhadri, A., Zeggwagh, N. A., Maghrani, M., Jouad, H., and Eddouks, M. Anti-hyperglycaemic activity of the aqueous extract of Origanum vulgare growing wild in Tafilalet region. J Ethnopharmacol. 2004;92(2-3):251-256. PubMed
  9. McCue, P., Vattem, D., and Shetty, K. Inhibitory effect of clonal oregano extracts against porcine pancreatic amylase in vitro. Asia Pac.J Clin.Nutr. 2004;13(4):401-408.
  10. Ragi, J., Pappert, A., Rao, B., Havkin-Frenkel, D., and Milgraum, S. Oregano extract ointment for wound healing: a randomized, double-blind, petrolatum-controlled study evaluating efficacy. J.Drugs Dermatol. 2011;10(10):1168-1172.
  11. Singletary K. Oregano: overview of the literature on health benefits. Nutrition Today 2010;45(3):129-38.
  12. Silva MLAE, Lucarini R, Dos Santos FF, et al. Hypoglycemic effect of rosmarinic acid-rich infusion (RosCE) from Origanum vulgare in alloxan-induced diabetic rats. Nat Prod Res 2022;36(17):4525-4531.

See these in context on the Oregano monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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