Interactions on record — worth a quick check against your medications. Based on 6 of 7 ingredients. Check your meds →
Dietary supplement

Woman Ingredients & Drug Interactions

by Host Defense MycoBotanicals

Woman label
See full label image
Capsule Category: Other Combinations
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 23, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Woman against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Woman is a dietary supplement by Host Defense MycoBotanicals with 7 active ingredients. Its ingredients are commonly taken for immune support, blood sugar support in diabetes, high blood pressure.Based on those ingredients, 737 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Reishi, Mesima, Maitake. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

Jump to a section

Check Your Meds Against Woman by Host Defense MycoBotanicals

Ask about any prescription or over-the-counter medication and we check it for interactions with Woman by Host Defense MycoBotanicals — and tell you which ingredient is responsible.

Pharmacist-reviewed data Checks every ingredient Answer in seconds
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HelloPharmacist Scorecard of Woman by Host Defense MycoBotanicals

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Jul 11, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 7 of its 7 active ingredients.
  • No proprietary blends here — you can verify the dose of every single component.

Host Defense MycoBotanicals Woman is a 7-ingredient blend of mushroom and plant extracts in capsule form. The active ingredients are Turkey Tails, Maitake mushroom, Reishi mushroom, Mesima, Shatavari (Asparagus racemosus) root extract, Broccoli sprouts powder, and Chasteberry seed extract.

The capsules also contain inactive ingredients — dried myceliated brown rice, Pullulan, and Maltodextrin — that serve as carriers and binders.

Does it work?

Not established
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not established

The graded evidence we hold for these ingredients covers different conditions than the ones this product is marketed for, so there's no established rating for its stated use.

Why this rating?
  • The label markets this product for: Women's health and reproductive support.
  • We looked for evidence on: Lactation, Polycystic ovary syndrome (PCOS), Sexual desire, Hormonal balance, Menopause, Menopausal symptoms — and 1 related terms.
  • The closest evidence on file: Maitake Mushroom is rated "Insufficient Reliable Evidence To Rate" for Polycystic ovary syndrome (PCOS) (Natural Medicines).
  • Also on file: Vitex Agnus-castus is rated "Insufficient Reliable Evidence To Rate" for Lactation, Menopausal symptoms, Polycystic ovary syndrome (PCOS).
  • Also on file: Asparagus Racemosus is rated "Insufficient Reliable Evidence To Rate" for Lactation, Sexual desire.

The evidence for most uses in this product is not established in our data. Broccoli sprouts powder is rated Possibly Effective for colorectal cancer prevention, but for the other ingredients and conditions listed — including maitake for chemotherapy side effects, reishi for altitude sickness and Alzheimer disease, shatavari for lactation support and sexual desire, and chasteberry — the reliable evidence is insufficient to rate them.

This doesn't mean they don't work; it means large, well-designed human studies are lacking.

The evidence, ingredient by ingredient Maitake Mushroom Reishi Mushroom Black Hoof Mushroom Asparagus Racemosus Broccoli Vitex Agnus-castus

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 4 of the 6 matched ingredients.
  • Pregnancy & breastfeeding safety ratings cover 6 of 6.
  • General safety write-ups exist for 6 of 6.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Maitake and reishi mushrooms are generally well tolerated, though some trial participants reported stomach upset, diarrhea, nausea, and (rarely) rash or itching. Reishi can also cause dizziness and dry mouth.

Shatavari is traditionally used and considered well tolerated, but high-quality safety data are limited. Broccoli sprouts powder is safe as food in normal amounts; at high doses concentrated extracts may cause loose stools, diarrhea, and abdominal cramping.

For pregnancy: Maitake and reishi concentrated supplements should be avoided — not enough safety data. Shatavari safety in pregnancy is not well established, so it's best avoided unless your doctor advises otherwise.

Broccoli as food is fine in normal amounts during pregnancy (Likely Safe), but concentrated supplements should be avoided unless approved. For breastfeeding: Maitake and reishi concentrated supplements should be avoided.

Shatavari is traditionally used to support milk supply, but reliable safety data are lacking — use only under professional guidance. Broccoli sprout extract safety while breastfeeding is not well established.

Side effects, ingredient by ingredient Maitake Mushroom Reishi Mushroom Black Hoof Mushroom Asparagus Racemosus Broccoli Vitex Agnus-castus

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 6 of the 6 matched ingredients can interact with medications — Maitake Mushroom, Reishi Mushroom, Vitex Agnus-castus, Broccoli, Asparagus Racemosus, among others.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: anticoagulant / antiplatelet drugs; immunosuppressants / transplant drugs; diabetes medications; lithium.
  • For scale: 737 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before taking this product, double-check with your pharmacist if you take warfarin or other blood thinners, blood pressure medication, blood sugar medication, water pills (diuretics), or lithium. Also check if you take any drug metabolized by your liver's CYP1A2 or CYP2A6 enzymes — broccoli sprouts in this formula can speed up how your body clears them.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with no established evidence rating for its marketed use. Moderate medication interactions have been identified, and safety information is well characterized.

Host Defense MycoBotanicals Woman is a multiingredient mushroom and plant formula. If you take blood pressure medication, blood sugar medication, blood thinners, water pills, lithium, or drugs metabolized by your liver's CYP1A2 or CYP2A6 enzymes, you need to check your specific medications before starting this product.

Talk to your pharmacist before adding it to your routine.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 6 of 7 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Feb 25, 2019.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Woman, straight from the product label.

Brand Host Defense MycoBotanicals
Barcode (UPC) 633422038728
Net contents 60 Vegetarian Capsule(s)
Market status On market
Date entered into DSLD Feb 25, 2019
DSLD ID 200094
Product type Other Combinations
Supplement form Capsule
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Organic, Adult Female (18 - 50 Years), Gluten Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Woman by Host Defense MycoBotanicals, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
2 Capsule(s)
Maximum serving Sizes:
2 Capsule(s)
Servings per container
30
UPC/BARCODE
633422038728
IngredientAmount% DV
Turkey Tails250 mg--
Maitake100 mg--
Reishi100 mg--
Mesima100 mg--
Shatavari (Asparagus racemosus) root extract250 mg--
Broccoli (Brassica oleracea) sprouts powder150 mg--
Chasteberry (Vitex agnus-castus) seed extract50 mg--

Other ingredients: dried myceliated Brown Rice, Pullulan, Maltodextrin

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Formula

Made with organic mushroom mycelium, shatavari & chasteberry

Supports hormonal balance

Suggested/Recommended/Usage/Directions

Directions for use: As a dietary supplement, take 2 capsules once per day. Can be taken with food or on an empty stomach or as recommended by your healthcare advisor.

Precautions

Keep out of reach of children.

Not to be used during pregnancy or lactation. If you take pharmaceutical drugs, please consult your health practitioner before using this product.

General

NCWM60 REV C2

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

Seals/Symbols

Producer Certified Organic Washington State Dept. of Agriculture Non GMO Project Verified

Formulation

Non GMO

Gluten free

Certified Organic by the Washington State Department of Agriculture.

FDA Statement of Identity

Dietary Supplement

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Woman by Host Defense MycoBotanicals label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Woman label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Woman by Host Defense MycoBotanicals

These are the 7 active ingredients this product is made of. Select any to open its full monograph.

Serving size2 Capsule(s) Dosage formCapsule Servings per container30 Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

Turkey Tails

250 mg per serving

Maitake

Interacts with
260 drugs
100 mg per serving

Maitake is an edible mushroom long used as food and in traditional Japanese medicine, and it is being studied for possible immune, blood sugar, and bl...

Maitake monograph & interactions

Reishi

Interacts with
375 drugs
100 mg per serving

Reishi is a traditional Asian mushroom widely used to support the immune system and overall wellness. Human evidence for most of its claimed benefits...

Reishi monograph & interactions

Mesima

Interacts with
308 drugs
100 mg per serving

Black Hoof Mushroom (Phellinus linteus) is a medicinal mushroom long used in East Asian traditional medicine, mainly for immune support. Most of the s...

Mesima monograph & interactions

Shatavari (Asparagus racemosus) root extract

Interacts with
76 drugs
250 mg per serving

Asparagus racemosus, often called shatavari, is an Ayurvedic herb traditionally used to support women's health, digestion, and overall vitality. Human...

Shatavari (Asparagus racemosus) root extract monograph & interactions

Broccoli (Brassica oleracea) sprouts powder

Interacts with
187 drugs
150 mg per serving

Broccoli is a nutritious cruciferous vegetable rich in fiber, vitamins, and plant compounds like sulforaphane that have drawn scientific interest for...

Broccoli (Brassica oleracea) sprouts powder monograph & interactions

Chasteberry (Vitex agnus-castus) seed extract

Interacts with
121 drugs
50 mg per serving

Vitex (chasteberry) is an herbal remedy most often used for PMS and menstrual cycle problems, and the strongest evidence is for easing some PMS sympto...

Chasteberry (Vitex agnus-castus) seed extract monograph & interactions

Other (inactive) ingredients: Dried myceliated Brown Rice, Pullulan, Maltodextrin. These complete the product’s ingredient list but are not active constituents.

Interaction report

Woman by Host Defense MycoBotanicals Drug Interactions

Want to check YOUR meds against Woman?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
737Drugs
737 Moderate

Ingredients driving the most interactions

Reishi 375
Mesima 308
Maitake 260
Broccoli (Brassica oleracea) sprouts powder 187
Chasteberry (Vitex agnus-castus) seed extract 121

Individual Drug Interactions

The ingredients in Woman interact with 737 drugs. Click any drug to see the details.

6 of the 7 ingredients in Woman interact with drugs. Each result below shows which ingredient is responsible. Reishi Mesima Maitake Broccoli (Brassica oleracea) sprouts powder Chasteberry (Vitex agnus-castus) seed extract Shatavari (Asparagus racemosus) root extract

Each ingredient & the kinds of drugs it affects

For each ingredient in Woman with known interactions, here are the types of medications they can affect. Open any type for the detail — or search your exact drug in the checker above.

Reishi3 drug types · 375 drugs

Anticoagulant/Antiplatelet Drugs

Theoretically, high doses of reishi mushroom might increase the risk of bleeding.
A dose of 1.5 grams daily of reishi mushroom does not seem to decrease platelet aggregation, but a higher dose of 3 grams daily does.

Likelihood Possible Evidence D
Antidiabetes Drugs

Theoretically, reishi mushroom might have additive effects with antidiabetes drugs.
Animal research suggests that reishi mushroom decreases blood sugar. However, in patients with type 2 diabetes, taking reishi mushroom does not reduce fasting glucose levels, and its effects on glycated hemoglobin are inconsistent.

Likelihood Possible Evidence D
Antihypertensive Drugs

Theoretically, concurrent use of reishi mushroom with antihypertensive drugs might increase the risk of hypotension.
Reishi mushroom has shown hypotensive activity in animal research. Clinical evidence suggests that reishi mushroom reduces blood pressure in some, but not all, patients with hypertension.

Likelihood Possible Evidence D
Reishi full monograph & interactions

Mesima3 drug types · 308 drugs

Cytochrome P450 1A2 (Cyp1A2) Substrates

Theoretically, black hoof mushroom might increase the levels and clinical effects of CYP1A2 substrates.
In vitro, polysaccharides from black hoof mushroom grown in culture inhibit CYP1A2. This effect has not been reported in humans.

Likelihood Possible Evidence D
Cytochrome P450 2E1 (Cyp2E1) Substrates

Theoretically, black hoof mushroom might increase the levels and clinical effects of CYP2E1 substrates.
In vitro, polysaccharides from black hoof mushroom grown in culture inhibit CYP2E1. This effect has not been reported in humans.

Likelihood Possible Evidence D
Immunosuppressants

Theoretically, black hoof mushroom might reduce the effects of immunosuppressant medications.
In animal research, polysaccharides from black hoof mushroom and black hoof mushroom extract stimulate immune responses.

Likelihood Possible Evidence D
Mesima full monograph & interactions

Maitake3 drug types · 260 drugs

Antidiabetes Drugs

Theoretically, combining maitake mushroom with antidiabetes drugs might increase the risk of hypoglycemia.
Clinical research shows that taking maitake mushroom polysaccharide (MMP) can lower blood glucose levels in patients with types 2 diabetes.

Likelihood Possible Evidence B
Antihypertensive Drugs

Theoretically, combining maitake mushroom with antihypertensive drugs might increase the risk of hypotension.
Animal research shows that maitake mushroom can lower blood pressure.

Likelihood Possible Evidence D
Warfarin (Coumadin)

There is limited evidence that maitake mushroom may increase the anticoagulant effects of warfarin.
In a case report, a patient previously stabilized on warfarin developed an elevated international normalized ratio (INR) of 5.1 after taking maitake mushroom (Grifron-Pro Maitake D-Fraction) 1 drop/kg daily in three divided doses for one week. The elevated INR resolved after holding warfarin for two days, then reducing the dose by 11%. It is thought that the beta-glucan constituent of maitake mushroom might cause warfarin dissociation from proteins, resulting in increased free warfarin levels and increased warfarin effects.

Likelihood Possible Evidence D
Maitake full monograph & interactions

Broccoli (Brassica oleracea) sprouts powder2 drug types · 187 drugs

Cytochrome P450 1A2 (Cyp1A2) Substrates

Theoretically, broccoli might reduce the levels and effects of drugs metabolized by CYP1A2.
Pharmacokinetic research in humans shows that eating 500 grams of fresh broccoli daily for 6-12 days can increase CYP1A2 activity by 10% to 200%. Induction of CYP1A2 activity by broccoli is attributed to its glucosinolate constituents.

Likelihood Possible Evidence B
Cytochrome P450 2A6 (Cyp2A6) Substrates

Theoretically, broccoli might reduce the levels and effects of drugs metabolized by CYP2A6.
Pharmacokinetic research in humans shows that eating 500 grams of broccoli daily for 6 days increases CYP2A6 activity by 135% to 550%. Induction of CYP2A6 activity is attributed to its glucosinolate constituents.

Likelihood Possible Evidence B
Broccoli (Brassica oleracea) sprouts powder full monograph & interactions

Chasteberry (Vitex agnus-castus) seed extract5 drug types · 121 drugs

Antipsychotic Drugs

Theoretically, vitex agnus-castus could interfere with the activity of antipsychotic drugs.
Vitex agnus-castus might interfere with the action of dopamine antagonists such as antipsychotic drugs due to its dopamine agonist effects.

Likelihood Possible Evidence D
Contraceptive Drugs

Theoretically, vitex agnus-castus could interfere with oral contraceptives.
Vitex agnus-castus might interfere with the efficacy of oral contraceptives due to possible hormone modulating activity.

Likelihood Possible Evidence B
Dopamine Agonists

Theoretically, vitex agnus-castus could interfere with dopamine agonists.
Vitex agnus-castus might potentiate the actions of dopaminergic agonists due to possible dopaminergic effects.

Likelihood Possible Evidence D
Estrogens

Theoretically, vitex agnus-castus could interfere with the activity of estrogens.
Vitex agnus-castus has hormone modulating activity that can interfere with the efficacy of hormone replacement therapy.

Likelihood Probable Evidence D
Metoclopramide (Reglan)

Theoretically, dopaminergic effects of vitex agnus-castus could interfere with metoclopramide.
Vitex agnus-castus might interfere with the action of dopamine antagonists such as metoclopramide due to its possible dopaminergic effects.

Likelihood Possible Evidence D
Chasteberry (Vitex agnus-castus) seed extract full monograph & interactions

Shatavari (Asparagus racemosus) root extract2 drug types · 76 drugs

Diuretic Drugs

Theoretically, asparagus racemosus root might increase diuresis and electrolyte loss when used with diuretic drugs.
Animal studies show that asparagus racemosus root has diuretic effects when used in high doses. This effect has not been reported in humans.

Likelihood Possible Evidence D
Lithium

Theoretically, Asparagus racemosus root could reduce excretion and increase levels of lithium.
Animal research suggests that Asparagus racemosus root has diuretic properties when used in high doses. Therefore, it might reduce excretion and increase levels of lithium. The dose of lithium might need to be decreased.

Likelihood Probable Evidence D
Shatavari (Asparagus racemosus) root extract full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Woman, from the product label.

Host Defense MycoBotanicals

See all Host Defense MycoBotanicals products
Name
Fungi Perfecti, LLC
Street Address
PO Box 7634
City
Olympia
State
WA
ZipCode
98507
Phone Number
877-504-6926
Web Address
Hostdefense.com
Pharmacist Counseling Corner

Woman by Host Defense MycoBotanicals: Common Questions

Does Woman by Host Defense MycoBotanicals interact with any medications?
Yes. Based on its ingredients, Woman has a known interaction with 737 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Woman contains 7 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
What's in Host Defense MycoBotanicals Woman?
It's a blend of seven active ingredients: four medicinal mushrooms (Turkey Tails, Maitake, Reishi, and Mesima) plus Shatavari root extract, Broccoli sprouts powder, and Chasteberry seed extract. They're combined with brown rice, Pullulan, and Maltodextrin as inactive carriers.
Does broccoli sprouts powder in this formula interact with my medications?
Yes — broccoli can speed up how your liver clears certain drugs. It affects enzymes called CYP1A2 and CYP2A6, which handle many medications. Ask your pharmacist if any of your prescriptions use those pathways.
Can I take this if I'm on warfarin?
Not without checking first. Maitake mushroom in this product may increase warfarin's blood-thinning effect — one case report showed an unsafe spike in bleeding risk. Talk to your doctor or pharmacist before starting.
Is it safe during pregnancy?
The maitake and reishi mushroom concentrates in this product should be avoided in pregnancy — not enough safety data. Shatavari is also best avoided unless your doctor says it's okay. Broccoli as food is safe, but concentrated supplements aren't well studied. Talk to your doctor for personalized advice.
What side effects should I watch for?
The mushroom ingredients may cause stomach upset, diarrhea, nausea, and rarely rash or itching. Reishi can also cause dizziness. Broccoli sprouts at high doses may trigger loose stools and cramping. Most people tolerate these ingredients well.
Does this product work for the conditions on the label?
Broccoli sprouts is rated Possibly Effective for colorectal cancer. For the other uses — maitake and reishi for chemotherapy side effects, shatavari for lactation, chasteberry, and others — the research evidence is not established in our data. Doesn't mean they don't work; means large human studies are missing.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Woman label
Go deeper

The Full Monographs Behind Woman’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Maitake Mushroom

Interacts with 260 drugs

Maitake is an edible mushroom long used as food and in traditional Japanese medicine, and it is being studied for possible immune, blood sugar, and blood pressure effects. The human evidence...

Read the full Maitake Mushroom monograph → Herb & supplement monograph

Reishi Mushroom

Interacts with 375 drugs

Reishi is a traditional Asian mushroom widely used to support the immune system and overall wellness. Human evidence for most of its claimed benefits is limited or low-quality, so it should...

Read the full Reishi Mushroom monograph → Herb & supplement monograph

Black Hoof Mushroom

Interacts with 308 drugs

Black Hoof Mushroom (Phellinus linteus) is a medicinal mushroom long used in East Asian traditional medicine, mainly for immune support. Most of the supporting evidence comes from laboratory...

Read the full Black Hoof Mushroom monograph → Herb & supplement monograph

Asparagus Racemosus

Interacts with 76 drugs

Asparagus racemosus, often called shatavari, is an Ayurvedic herb traditionally used to support women's health, digestion, and overall vitality. Human evidence for most of these uses is limi...

Read the full Asparagus Racemosus monograph → Herb & supplement monograph

Broccoli

Interacts with 187 drugs

Broccoli is a nutritious cruciferous vegetable rich in fiber, vitamins, and plant compounds like sulforaphane that have drawn scientific interest for health benefits. Eating broccoli as food...

Read the full Broccoli monograph → Herb & supplement monograph

Vitex Agnus-castus

Interacts with 121 drugs

Vitex (chasteberry) is an herbal remedy most often used for PMS and menstrual cycle problems, and the strongest evidence is for easing some PMS symptoms. It is generally well tolerated by ma...

Read the full Vitex Agnus-castus monograph →
Sources

Sources & How We Checked

Woman's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 60 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Maitake Mushroom 8 references
  1. Kabir Y, Kimura S. Dietary mushrooms reduce blood pressure in spontaneously hypertensive rats (SHR). J Nutr Sci Vitaminol (Tokyo) 1989;35:91-4. PubMed
  2. Kabir Y, Yamaguchi M, Kimura S. Effect of shiitake (Lentinus edodes) and maitake (Grifola frondosa) mushrooms on blood pressure and plasma lipids of spontaneously hypertensive rats. J Nutr Sci Vitaminol (Tokyo) 1987;33:341-6. PubMed
  3. Konno S, Tortorelis DG, Fullerton SA, et al. A possible hypoglycaemic effect of maitake mushroom on Type 2 diabetic patients. Diabet Med 2001;18:1010. PubMed
  4. Chen JT, Tominaga K, Sato Y, et al. Maitake mushroom (Grifola frondosa) extract induces ovulation in patients with polycystic ovary syndrome: a possible monotherapy and a combination therapy after failure with first-line clomiphene citrate. J Altern Compl
  5. Hanselin MR, Vande Griend JP, Linnebur SA. INR elevation with maitake extract in combination with warfarin. Ann Pharmacother 2010;44:223-4. PubMed
  6. Talpur, N. A., Echard, B. W., Fan, A. Y., Jaffari, O., Bagchi, D., and Preuss, H. G. Antihypertensive and metabolic effects of whole Maitake mushroom powder and its fractions in two rat strains. Mol.Cell Biochem. 2002;237(1-2):129-136. PubMed
  7. Deng, G., Lin, H., Seidman, A., Fornier, M., D'Andrea, G., Wesa, K., Yeung, S., Cunningham-Rundles, S., Vickers, A. J., and Cassileth, B. A phase I/II trial of a polysaccharide extract from Grifola frondosa (Maitake mushroom) in breast cancer patients: i
  8. Wesa KM, Cunningham-Rundles S, Klimek VM, et al. Maitake mushroom extract in myelodysplastic syndromes (MDS): a phase II study. Cancer Immunol Immunother 2015;64(2):237-47. PubMed

See these in context on the Maitake Mushroom monograph →

Reishi Mushroom 17 references
  1. McGuffin M, Hobbs C, Upton R, Goldberg A, eds. American Herbal Products Association's Botanical Safety Handbook. Boca Raton, FL: CRC Press, LLC 1997.
  2. Tao J, Feng KY. Experimental and clinical studies on inhibitory effect of ganoderma lucidum on platelet aggregation. J Tongji Med Univ 1990;10:240-3. PubMed
  3. Singh AB, Gupta SK, Pereira BM, Prakash D. Sensitization to Ganoderma lucidum in patients with respiratory allergy in India. Clin Exp Allergy 1995;25:440-7.
  4. Lee SY, Rhee HM. Cardiovascular effects of mycelium extract of Ganoderma lucidum: inhibition of sympathetic outflow as a mechanism of its hypotensive action. Chem Pharm Bull (Tokyo) 1990;38:1359-64. PubMed
  5. Kwok Y, Ng KFJ, Li, CCF, et al. A prospective, randomized, double-blind, placebo-controlled study of the platelet and global hemostatic effects of Ganoderma lucidum (Ling-Zhi) in healthy volunteers. Anesth Analg 2005;101:423-6. PubMed
  6. Wanmuang, H., Leopairut, J., Kositchaiwat, C., Wananukul, W., and Bunyaratvej, S. Fatal fulminant hepatitis associated with Ganoderma lucidum (Lingzhi) mushroom powder. J Med Assoc Thai. 2007;90(1):179-181.
  7. Seto, S. W., Lam, T. Y., Tam, H. L., Au, A. L., Chan, S. W., Wu, J. H., Yu, P. H., Leung, G. P., Ngai, S. M., Yeung, J. H., Leung, P. S., Lee, S. M., and Kwan, Y. W. Novel hypoglycemic effects of Ganoderma lucidum water-extract in obese/diabetic (+db/+db
  8. Chu, T. T., Benzie, I. F., Lam, C. W., Fok, B. S., Lee, K. K., and Tomlinson, B. Study of potential cardioprotective effects of Ganoderma lucidum (Lingzhi): results of a controlled human intervention trial. Br.J.Nutr. 2012;107(7):1017-1027.
  9. Jin, X., Ruiz, Beguerie J., Sze, D. M., and Chan, G. C. Ganoderma lucidum (Reishi mushroom) for cancer treatment. Cochrane.Database.Syst.Rev. 2012;6:CD007731.
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Black Hoof Mushroom 6 references
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Asparagus Racemosus 1 reference
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Broccoli 5 references
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Vitex Agnus-castus 23 references
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DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

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