WomanCare Ingredients & Drug Interactions
by Herbs SRA
What is this page for?
First and foremost: checking WomanCare against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.
Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy
WomanCare is a dietary supplement by Herbs SRA with 3 active ingredients. Its ingredients are commonly taken for anxiety and stress, sleep problems, relaxation.Based on those ingredients, 527 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Gamma-Aminobutyric Acid, Chasteberry Fruit Extract. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.
Check Your Meds Against WomanCare by Herbs SRA
Ask about any prescription or over-the-counter medication and we check it for interactions with WomanCare by Herbs SRA — and tell you which ingredient is responsible.
AI summaries are generated from our interaction database for education only — always confirm with your pharmacist. How we use AI
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HelloPharmacist Scorecard of WomanCare by Herbs SRA
Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.
What’s inside
Full disclosure
WomanCare contains three active ingredients: Gamma-Aminobutyric Acid (GABA), Chasteberry Fruit Extract, and Muira Puama Bark, Root Extract. GABA is a neurotransmitter your body makes naturally; the supplement form is meant to support relaxation and nervous system function.
Chasteberry and Muira Puama are plant extracts traditionally used to support women's health and sexual function, respectively. The capsules also contain cellulose as an inactive ingredient.
Does it work?
Moderate evidence
The evidence supporting these ingredients is limited. GABA has been studied for anxiety, ADHD, athletic performance, cerebral palsy, and chronic bronchitis, but the data we hold rates all of these as having insufficient reliable evidence.
Muira Puama has been studied for sexual dysfunction and erectile dysfunction, but again, our data rates the evidence insufficient. Chasteberry's effectiveness is not rated in our data.
If you're considering this product for a specific health goal, talk with your pharmacist or doctor about what the research actually shows.
How safe is it?
Well-documented data
GABA is generally well tolerated when taken by mouth over the short term, though long-term safety hasn't been well studied. The most common side effects reported are drowsiness, stomach upset, minor throat burning, muscle weakness, and nausea.
One case of temporary loss of menstrual periods was reported in someone taking GABA plus another supplement. Muira Puama has limited human safety data; it's traditionally used in small amounts, but we don't know much about its safety profile.
Chasteberry safety data aren't on file here.
Meds to double-check
Moderate interaction found
Check your blood pressure medications before you start — GABA may lower your blood pressure further (Moderate risk). Also double-check any CNS depressants you're on, including sleep aids, anti-anxiety drugs, or opioids (Minor risk).
For Chasteberry Fruit Extract and Muira Puama, we hold no interaction data, so we can't flag specific drug concerns, but mention this product to your pharmacist anyway.
The bottom line
Scorecard at a glanceFully disclosed formula with some supporting evidence for its stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.
If you take blood pressure medications or drugs that cause drowsiness — sedatives, sleep aids, anti-anxiety meds, opioids — check your exact medications with the tool below before starting. GABA's long-term safety and the effectiveness of all three ingredients need more research.
Talk with your pharmacist about whether this product fits your situation.
Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI
Assessment coverage: 3 of 3 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Aug 22, 2024.
This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed
General information
Key facts about WomanCare, straight from the product label.
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.
Supplement Facts
The label details for WomanCare by Herbs SRA, sourced from the NIH Dietary Supplement Label Database.
Supplement Facts
| Ingredient | Amount | % DV |
|---|---|---|
| Gamma-Aminobutyric Acid | 136 mg | -- |
| Chasteberry Fruit Extract | 132 mg | -- |
| Muira Puama Bark, Root Extract | 132 mg | -- |
Other ingredients: Cellulose
Tap any ingredient to jump to its full detail below.
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Suggested/Recommended/Usage/Directions
Suggested use: As a dietary supplement, take two (2) capsules twice daily. For best results, take capsules in the morning and the afternoon with 8oz. of water.
Precautions
Caution: Do not exceed recommended dose. Do not use if safety seal is damaged or missing.
Pregnant or nursing mothers, children under the age of 18, and individuals with a known medical condition should consult a physician before using this or any dietary supplement.
Pregnant or nursing mothers, children under the age of 18, and individuals with a known medical condition should consult a physician before using this or any dietary supplement. Keep out of the reach of children.
Storage
Store in a cool, dry place.
FDA Disclaimer Statement
These statements have not been evaluated by the FDA (Food and Drug Administration). This product is not intended to diagnose, treat, cure, mitigate or prevent any disease or health condition.
General Statements
Herbs SRA Let the herbs improve your health
Follow us: Facebook Herbs SRA
FDA Statement of Identity
Dietary Supplement
Formulation
Promotes proper function of the female reproductive system
Is this label outdated? Report a formula or label change and our pharmacy team will review it.
WomanCare by Herbs SRA label
The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.
Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.
View the full label (PDF)The Ingredients in WomanCare by Herbs SRA
These are the 3 active ingredients this product is made of. Select any to open its full monograph.
Serving size2 Capsule(s) Dosage formCapsule Servings per container60 Amounts shown are per serving.
Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.
Gamma-Aminobutyric Acid
Interacts with419 drugs
GABA is a calming chemical messenger (neurotransmitter) that your body makes on its own, and it is sold as a supplement for stress, anxiety, and sleep...
Gamma-Aminobutyric Acid monograph & interactionsChasteberry Fruit Extract
Interacts with121 drugs
Vitex (chasteberry) is an herbal remedy most often used for PMS and menstrual cycle problems, and the strongest evidence is for easing some PMS sympto...
Chasteberry Fruit Extract monograph & interactionsMuira Puama Bark, Root Extract
No knowninteractions
Muira puama is a Brazilian plant traditionally used as an aphrodisiac and general tonic, often nicknamed 'potency wood.' Human research is very limite...
Muira Puama Bark, Root Extract monograph & interactionsOther (inactive) ingredients: Cellulose. These complete the product’s ingredient list but are not active constituents.
WomanCare by Herbs SRA Drug Interactions
HelloPharmacist Interaction Report
WomanCare by Herbs SRA contains ingredients that interact with medications.
GABA, one of the three active ingredients, may increase the risk of low blood pressure (hypotension) if you take blood pressure medications — this is a Moderate-severity concern. GABA may also have additive sedative effects with CNS depressants (drugs that slow your central nervous system, like sleep aids, anti-anxiety medications, or opioids), though the clinical significance isn't clear; this is rated Minor.
Altogether, these interactions span 417 individual medications.
Read the full breakdown — every affected drug type, severity by severity
Charteberry Fruit Extract and Muira Puama Bark, Root Extract we could not check — we hold no interaction data for them. If you're on any blood pressure medication, sedating medication, or any other prescription, run your exact drugs through the checker below before you start.
Check your own medications below · Editorial policy · How we use AI
Want to check YOUR meds against WomanCare?
Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.
Go to the checkerIngredients driving the most interactions
Individual Drug Interactions
The ingredients in WomanCare interact with 527 drugs. Click any drug to see the details.
2 of the 3 ingredients in WomanCare interact with drugs. Each result below shows which ingredient is responsible. Gamma-Aminobutyric Acid Chasteberry Fruit Extract
Benazepril, HydrochlorothiazideLotensin HCT
How Benazepril, Hydrochlorothiazide interacts with WomanCare — through 1 ingredient. Tap an ingredient for the detail:
Gamma-aminobutyric AcidAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, taking GABA with antihypertensive drugs might increase the risk of hypotension.
Read the full Gamma-aminobutyric Acid + Benazepril, Hydrochlorothiazide interactionBendroflumethiazideAprinox, Naturetin, Neo-NaClex
How Bendroflumethiazide interacts with WomanCare — through 1 ingredient. Tap an ingredient for the detail:
Gamma-aminobutyric AcidAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, taking GABA with antihypertensive drugs might increase the risk of hypotension.
Read the full Gamma-aminobutyric Acid + Bendroflumethiazide interactionBendroflumethiazide, NadololCorzide
How Bendroflumethiazide, Nadolol interacts with WomanCare — through 1 ingredient. Tap an ingredient for the detail:
Gamma-aminobutyric AcidAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, taking GABA with antihypertensive drugs might increase the risk of hypotension.
Read the full Gamma-aminobutyric Acid + Bendroflumethiazide, Nadolol interactionBendroflumethiazide, Rauwolfia SerpentinaRauzide
How Bendroflumethiazide, Rauwolfia Serpentina interacts with WomanCare — through 1 ingredient. Tap an ingredient for the detail:
Gamma-aminobutyric AcidAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, taking GABA with antihypertensive drugs might increase the risk of hypotension.
Read the full Gamma-aminobutyric Acid + Bendroflumethiazide, Rauwolfia Serpentina interactionBenserazide, LevodopaMadopar, Prolopa
How Benserazide, Levodopa interacts with WomanCare — through 1 ingredient. Tap an ingredient for the detail:
Chasteberry Fruit ExtractDopamine Agonists Moderate
Interaction Summary
Theoretically, vitex agnus-castus could interfere with dopamine agonists.
Read the full Chasteberry Fruit Extract + Benserazide, Levodopa interactionBenzthiazideExna
How Benzthiazide interacts with WomanCare — through 1 ingredient. Tap an ingredient for the detail:
Gamma-aminobutyric AcidAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, taking GABA with antihypertensive drugs might increase the risk of hypotension.
Read the full Gamma-aminobutyric Acid + Benzthiazide interactionBetaxololBetoptic, Kerlone
How Betaxolol interacts with WomanCare — through 1 ingredient. Tap an ingredient for the detail:
Gamma-aminobutyric AcidAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, taking GABA with antihypertensive drugs might increase the risk of hypotension.
Read the full Gamma-aminobutyric Acid + Betaxolol interactionBirth Control PillsBirth control pills
How Birth Control Pills interacts with WomanCare — through 1 ingredient. Tap an ingredient for the detail:
Chasteberry Fruit ExtractContraceptive Drugs Moderate
Interaction Summary
Theoretically, vitex agnus-castus could interfere with oral contraceptives.
Read the full Chasteberry Fruit Extract + Birth Control Pills interactionBisoprololZebeta
How Bisoprolol interacts with WomanCare — through 1 ingredient. Tap an ingredient for the detail:
Gamma-aminobutyric AcidAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, taking GABA with antihypertensive drugs might increase the risk of hypotension.
Read the full Gamma-aminobutyric Acid + Bisoprolol interactionBisoprolol, HydrochlorothiazideZiac
How Bisoprolol, Hydrochlorothiazide interacts with WomanCare — through 1 ingredient. Tap an ingredient for the detail:
Gamma-aminobutyric AcidAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, taking GABA with antihypertensive drugs might increase the risk of hypotension.
Read the full Gamma-aminobutyric Acid + Bisoprolol, Hydrochlorothiazide interactionBosentanTracleer
How Bosentan interacts with WomanCare — through 1 ingredient. Tap an ingredient for the detail:
Gamma-aminobutyric AcidAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, taking GABA with antihypertensive drugs might increase the risk of hypotension.
Read the full Gamma-aminobutyric Acid + Bosentan interactionBrexpiprazoleRexulti
How Brexpiprazole interacts with WomanCare — through 1 ingredient. Tap an ingredient for the detail:
Chasteberry Fruit ExtractAntipsychotic Drugs, Dopamine Agonists Moderate
Interaction Summary
Theoretically, vitex agnus-castus could interfere with the activity of antipsychotic drugs.
Read the full Chasteberry Fruit Extract + Brexpiprazole interactionBromocriptineParlodel
How Bromocriptine interacts with WomanCare — through 1 ingredient. Tap an ingredient for the detail:
Chasteberry Fruit ExtractDopamine Agonists Moderate
Interaction Summary
Theoretically, vitex agnus-castus could interfere with dopamine agonists.
Read the full Chasteberry Fruit Extract + Bromocriptine interactionBumetanideBurinex
How Bumetanide interacts with WomanCare — through 1 ingredient. Tap an ingredient for the detail:
Gamma-aminobutyric AcidAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, taking GABA with antihypertensive drugs might increase the risk of hypotension.
Read the full Gamma-aminobutyric Acid + Bumetanide interactionBumetanide (iv)Bumex
How Bumetanide (iv) interacts with WomanCare — through 1 ingredient. Tap an ingredient for the detail:
Gamma-aminobutyric AcidAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, taking GABA with antihypertensive drugs might increase the risk of hypotension.
Read the full Gamma-aminobutyric Acid + Bumetanide (iv) interactionBumetanide (oral)Bumex
How Bumetanide (oral) interacts with WomanCare — through 1 ingredient. Tap an ingredient for the detail:
Gamma-aminobutyric AcidAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, taking GABA with antihypertensive drugs might increase the risk of hypotension.
Read the full Gamma-aminobutyric Acid + Bumetanide (oral) interactionButaperazineRepoise
How Butaperazine interacts with WomanCare — through 1 ingredient. Tap an ingredient for the detail:
Chasteberry Fruit ExtractAntipsychotic Drugs Moderate
Interaction Summary
Theoretically, vitex agnus-castus could interfere with the activity of antipsychotic drugs.
Read the full Chasteberry Fruit Extract + Butaperazine interactionCandesartan CilexetilAmias, Atacand
How Candesartan Cilexetil interacts with WomanCare — through 1 ingredient. Tap an ingredient for the detail:
Gamma-aminobutyric AcidAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, taking GABA with antihypertensive drugs might increase the risk of hypotension.
Read the full Gamma-aminobutyric Acid + Candesartan Cilexetil interactionCandesartan Cilexetil, HydrochlorothiazideAtacand HCT
How Candesartan Cilexetil, Hydrochlorothiazide interacts with WomanCare — through 1 ingredient. Tap an ingredient for the detail:
Gamma-aminobutyric AcidAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, taking GABA with antihypertensive drugs might increase the risk of hypotension.
Read the full Gamma-aminobutyric Acid + Candesartan Cilexetil, Hydrochlorothiazide interactionCaptoprilAcepril, Capoten
How Captopril interacts with WomanCare — through 1 ingredient. Tap an ingredient for the detail:
Gamma-aminobutyric AcidAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, taking GABA with antihypertensive drugs might increase the risk of hypotension.
Read the full Gamma-aminobutyric Acid + Captopril interactionCaptopril, HydrochlorothiazideAcezide, Capozide
How Captopril, Hydrochlorothiazide interacts with WomanCare — through 1 ingredient. Tap an ingredient for the detail:
Gamma-aminobutyric AcidAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, taking GABA with antihypertensive drugs might increase the risk of hypotension.
Read the full Gamma-aminobutyric Acid + Captopril, Hydrochlorothiazide interactionCarbidopa, LevodopaDhivy, Rytary, Sinemet, Sinemet CR
How Carbidopa, Levodopa interacts with WomanCare — through 1 ingredient. Tap an ingredient for the detail:
Chasteberry Fruit ExtractDopamine Agonists Moderate
Interaction Summary
Theoretically, vitex agnus-castus could interfere with dopamine agonists.
Read the full Chasteberry Fruit Extract + Carbidopa, Levodopa interactionCarbidopa, Levodopa, EntacaponeStalevo
How Carbidopa, Levodopa, Entacapone interacts with WomanCare — through 1 ingredient. Tap an ingredient for the detail:
Chasteberry Fruit ExtractDopamine Agonists Moderate
Interaction Summary
Theoretically, vitex agnus-castus could interfere with dopamine agonists.
Read the full Chasteberry Fruit Extract + Carbidopa, Levodopa, Entacapone interactionCariprazine HydrochlorideVraylar
How Cariprazine Hydrochloride interacts with WomanCare — through 1 ingredient. Tap an ingredient for the detail:
Chasteberry Fruit ExtractAntipsychotic Drugs Moderate
Interaction Summary
Theoretically, vitex agnus-castus could interfere with the activity of antipsychotic drugs.
Read the full Chasteberry Fruit Extract + Cariprazine Hydrochloride interactionCarphenazineProketazin
How Carphenazine interacts with WomanCare — through 1 ingredient. Tap an ingredient for the detail:
Chasteberry Fruit ExtractAntipsychotic Drugs Moderate
Interaction Summary
Theoretically, vitex agnus-castus could interfere with the activity of antipsychotic drugs.
Read the full Chasteberry Fruit Extract + Carphenazine interactionCarteololCartrol, Ocupress
How Carteolol interacts with WomanCare — through 1 ingredient. Tap an ingredient for the detail:
Gamma-aminobutyric AcidAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, taking GABA with antihypertensive drugs might increase the risk of hypotension.
Read the full Gamma-aminobutyric Acid + Carteolol interactionCarvedilolCoreg, Coreg CR
How Carvedilol interacts with WomanCare — through 1 ingredient. Tap an ingredient for the detail:
Gamma-aminobutyric AcidAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, taking GABA with antihypertensive drugs might increase the risk of hypotension.
Read the full Gamma-aminobutyric Acid + Carvedilol interactionCeliprololCelicard
How Celiprolol interacts with WomanCare — through 1 ingredient. Tap an ingredient for the detail:
Gamma-aminobutyric AcidAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, taking GABA with antihypertensive drugs might increase the risk of hypotension.
Read the full Gamma-aminobutyric Acid + Celiprolol interactionChlorothiazideDiuril
How Chlorothiazide interacts with WomanCare — through 1 ingredient. Tap an ingredient for the detail:
Gamma-aminobutyric AcidAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, taking GABA with antihypertensive drugs might increase the risk of hypotension.
Read the full Gamma-aminobutyric Acid + Chlorothiazide interactionChlorothiazide, MethyldopaAldochlor, Aldoclor 150, Aldoclor 250
How Chlorothiazide, Methyldopa interacts with WomanCare — through 1 ingredient. Tap an ingredient for the detail:
Gamma-aminobutyric AcidAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, taking GABA with antihypertensive drugs might increase the risk of hypotension.
Read the full Gamma-aminobutyric Acid + Chlorothiazide, Methyldopa interactionEach ingredient & the kinds of drugs it affects
For each ingredient in WomanCare with known interactions, here are the types of medications they can affect. Open any type for the detail — or search your exact drug in the checker above.
Gamma-Aminobutyric Acid
Antihypertensive Drugs
Theoretically, taking GABA with antihypertensive drugs might increase the risk of hypotension.
Some clinical research shows that GABA can decrease blood pressure in patients with hypertension.
Cns Depressants
Theoretically, GABA might have additive sedative effects when used in conjunction with CNS depressants. However, it is unclear if this concern is clinically relevant.
Endogenous GABA has well-established relaxant effects and GABA(A) receptors have an established physiological role in sleep. However, the effects of GABA supplements are unclear, as it is unknown whether exogenous GABA crosses the blood-brain barrier. Although there have been limited reports of drowsiness or tiredness with GABA supplements, these effects have not been widely reported in clinical studies. Additionally, intravenous GABA 0.1-1 mg/kg has been shown to induce anxiety in a dose-dependent manner.
Chasteberry Fruit Extract
Antipsychotic Drugs
Theoretically, vitex agnus-castus could interfere with the activity of antipsychotic drugs.
Vitex agnus-castus might interfere with the action of dopamine antagonists such as antipsychotic drugs due to its dopamine agonist effects.
Contraceptive Drugs
Theoretically, vitex agnus-castus could interfere with oral contraceptives.
Vitex agnus-castus might interfere with the efficacy of oral contraceptives due to possible hormone modulating activity.
Dopamine Agonists
Theoretically, vitex agnus-castus could interfere with dopamine agonists.
Vitex agnus-castus might potentiate the actions of dopaminergic agonists due to possible dopaminergic effects.
Estrogens
Theoretically, vitex agnus-castus could interfere with the activity of estrogens.
Vitex agnus-castus has hormone modulating activity that can interfere with the efficacy of hormone replacement therapy.
Metoclopramide (Reglan)
Theoretically, dopaminergic effects of vitex agnus-castus could interfere with metoclopramide.
Vitex agnus-castus might interfere with the action of dopamine antagonists such as metoclopramide due to its possible dopaminergic effects.
Brand information
Manufacturer and brand details for WomanCare, from the product label.
WomanCare by Herbs SRA: Common Questions
Does WomanCare by Herbs SRA interact with any medications?
How can one product interact with so many drugs?
Where does this information come from?
Can I take WomanCare if I'm on blood pressure medication?
What are the most common side effects?
Is GABA proven to work for anxiety?
Can I take this while breastfeeding?
Is it safe to take long-term?
What does Muira Puama do?
Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
Not sure if WomanCare is safe with your meds?
Our pharmacists answer your medication & supplement questions — free.
Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.
The Full Monographs Behind WomanCare’s Ingredients
Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.
Gamma-aminobutyric Acid (gaba)
Interacts with 419 drugsGABA is a calming chemical messenger (neurotransmitter) that your body makes on its own, and it is sold as a supplement for stress, anxiety, and sleep. The science behind oral GABA supplemen...
Read the full Gamma-aminobutyric Acid (gaba) monograph → Herb & supplement monographVitex Agnus-castus
Interacts with 121 drugsVitex (chasteberry) is an herbal remedy most often used for PMS and menstrual cycle problems, and the strongest evidence is for easing some PMS symptoms. It is generally well tolerated by ma...
Read the full Vitex Agnus-castus monograph → Herb & supplement monographMuira Puama
Muira puama is a Brazilian plant traditionally used as an aphrodisiac and general tonic, often nicknamed 'potency wood.' Human research is very limited, so its benefits are not well proven,...
Read the full Muira Puama monograph →Sources & How We Checked
WomanCare's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.
- NIH Dietary Supplement Label Database (DSLD) — The official product label on file for this supplement.
- Natural Medicines (Therapeutic Research Center) — Evidence-graded clinical reference behind the ingredient interaction data.
Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.
The 37 references behind this product’s interaction data
Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.
Gamma-aminobutyric Acid (gaba) 12 references
- Cavagnini F, Invitti C, Pinto M, et al. Effect of acute and repeated administration of gamma aminobutyric acid (GABA) on growth hormone and prolactin secretion in man. Acta Endocrinol (Copenh) 1980;93:149-54.
- Nurnberger JI Jr, Berrettini WH, Simmons-Alling S, et al. Intravenous GABA administration is anxiogenic in man. Psychiatry Res 1986;19:113-7. PubMed
- Gershman RN, Vasilenko MA, Iliushina GG, et al. [Gammalon in the rehabilitation in infantile cerebral palsy]. Pediatr.Akus.Ginekol. 1977;(6):26-7.
- Loeb C, Benassi E, Bo, GP, et al. Preliminary evaluation of the effect of GABA and phosphatidylserine in epileptic patients. Epilepsy Res. 1987;1:209-12 . PubMed
- Inoue K, Shirai T, Ochiai H, et al. Blood-pressure-lowering effect of a novel fermented milk containing gamma-aminobutyric acid (GABA) in mild hypertensives. Eur J Clin Nutr 2003;57:490-95.
- ELLIOTT, K. A. and JASPER, H. H. Gammaaminobutyric acid. Physiol Rev. 1959;39(2):383-406.
- Winsky-Sommerer, R. Role of GABAA receptors in the physiology and pharmacology of sleep. Eur.J.Neurosci. 2009;29(9):1779-1794.
- Meldrum, B. S. GABAergic mechanisms in the pathogenesis and treatment of epilepsy. Br.J.Clin.Pharmacol. 1989;27 Suppl 1:3S-11S. PubMed
- Loeb, C., Marinari, U. M., Benassi, E., Besio, G., Cottalasso, D., Cupello, A., Maffini, M., Mainardi, P., Pronzato, M. A., and Scotto, P. A. Phosphatidylserine increases in vivo the synaptosomal uptake of exogenous GABA in rats. Exp.Neurol. 1988;99(2):4 PubMed
- Melis, G. B., Paoletti, A. M., Mais, V., and Fioretti, P. Interference of dopamine infusion on gamma-amino butyric acid (GABA)-stimulated prolactin increase. J.Endocrinol.Invest 1980;3(4):445-448.
- Boonstra E, de Kleijn R, Colzato LS, Alkemade A, Forstmann BU, Nieuwenhuis S. Neurotransmitters as food supplements: the effects of GABA on brain and behavior. Front Psychol. 2015 Oct 6;6:1520. doi: 10.3389/fpsyg.2015.01520. eCollection 2015. PubMed
- de Bie TH, Witkamp RF, Balvers MG, Jongsma MA. Effects of ?-aminobutyric acid supplementation on glucose control in adults with prediabetes: A double-blind, randomized, placebo-controlled trial. Am J Clin Nutr 2023;118(3):708-719. PubMed
See these in context on the Gamma-aminobutyric Acid (gaba) monograph →
Vitex Agnus-castus 23 references
- Wuttke W. Dopaminergic action of extracts of Agnus Castus. Forschende Komplementarmedizen 1996;3:329-30.
- Jarry H, Leonhardt S., Gorkow C, Wuttke W. In vitro prolactin but not LH and FSH release is inhibited by compounds in extracts of Agnus Castus: direct evidence for a dopaminergic principle by the dopamine receptor assay. Exp Clin Endocrinol 1994;102:448- PubMed
- Schellenberg R. Treatment for the premenstrual syndrome with agnus castus fruit extract: prospective, randomised, placebo-controlled study. BMJ 2001;322:134-7. PubMed
- Lauritzen CH, Reuter HD, Repges R, et al. Treatment of premenstrual tension syndrome with Vitex agnus castus: Controlled-double blind versus pyridoxine. Phytomedicine 1997;4:183-9.
- Berger D, Schaffner W, Schrader E, et al. Efficacy of Vitex agnus castus L. extract Ze 440 in patients with premenstrual syndrome (PMS). Arch Gynecol Obstet 2000;264:150-3.
- Loch EG, Selle H, Boblitz N. Treatment of premenstrual syndrome with a phytopharmaceutical formulation containing Vitex agnus castus. J Womens Health Gend Based Med 2000;9:315-20. PubMed
- Meier B, Berger D, Hoberg E, et al. Pharmacological activities of Vitex agnus-castus extracts in vitro. Phytomedicine 2000;7:373-81. PubMed
- Liu J, Burdette JE, Xu H, et al. Evaluation of estrogenic activity of plant extracts for the potential treatment of menopausal symptoms. J Agric Food Chem 2001;49:2472-9.. PubMed
- Wuttke W, Jarry H, Christoffel V, et al. Chaste tree (Vitex agnus-castus)--pharmacology and clinical indications. Phytomedicine 2003;10:348-57. PubMed
- Atmaca M, Kumru S, Tezcan E. Fluoxetine versus Vitex agnus castus extract in the treatment of premenstrual dysphoric disorder. Hum Psychopharmacol 2003;18:191-5..
- Daniele C, Thompson Coon J, Pittler MH, Ernst E. Vitex agnus castus: a systematic review of adverse events. Drug Saf 2005;28:319-32..
- Halaska M, Beles P, Gorkow C, Sieder C. Treatment of cyclical mastalgia with a solution containing a Vitex agnus castus extract: results of a placebo-controlled double-blind study. Breast 1999;8:175-81. PubMed
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