Interactions on record — worth a quick check against your medications. Based on 4 of 6 ingredients. Check your meds →
Dietary supplement

YinVive Ingredients & Drug Interactions

by ActiveHerb

Capsule Category: Botanical
Most serious interaction: Moderate
The interaction bottom line Most serious interaction: Moderate

YinVive is a dietary supplement by ActiveHerb with 6 active ingredients. Its ingredients are commonly taken for menstrual cramps and irregular periods, muscle cramps and spasms, anxiety and stress.Based on those ingredients, 1,382 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Tree Peony Root Bark Extract, Poria Sclerotium Extract, Asian Water Plantain Rhizome Extract. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

HelloPharmacist Scorecard of YinVive by ActiveHerb

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

What’s inside

Low disclosure
Ingredient Transparency · database check
Low

Most active ingredients don't disclose an individual amount — you can't tell how much of each you're getting.

Why this rating?
  • The label discloses an exact amount for 0 of its 6 active ingredients.
  • “Proprietary Blend Extract” is a proprietary blend — the label gives one combined amount (662 mg) without saying how much of each component you get.

YinVive contains six active ingredients, most of them traditional Chinese medicine extracts. The Proprietary Blend Extract combines multiple components listed separately.

The other five actives are Tree Peony Root Bark Extract, Asiatic Dogwood fruit without seed extract, Chinese Yam rhizome extract, Poria Sclerotium (mushroom) Extract, Asian Water Plantain Rhizome Extract, and Rehmannia Root Tuber Extract (cured). The capsule also contains inactive ingredients: hypromellose, dextrin, and magnesium stearate, which are standard binders and flow agents.

Does it work?

Not established
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not established

The graded evidence we hold for these ingredients covers different conditions than the ones this product is marketed for, so there's no established rating for its stated use.

Why this rating?
  • The label markets this product for: support adrenal function, back function and sexual wellness.
  • We looked for evidence on: Chronic fatigue syndrome (CFS), Dysmenorrhea, Muscle cramps, Polycystic ovary syndrome (PCOS), sexual dysfunction, lower back pain — and 1 related terms.
  • The closest evidence on file: Peony is rated "Insufficient Reliable Evidence To Rate" for Chronic fatigue syndrome (CFS) (Natural Medicines).
  • Also on file: Peony is rated "Insufficient Reliable Evidence To Rate" for Muscle cramps, Polycystic ovary syndrome (PCOS), Dysmenorrhea.
  • Also on file: Poria Mushroom is rated "Insufficient Reliable Evidence To Rate" for Chronic fatigue syndrome (CFS).

The evidence for most of YinVive's ingredients is not established in our data. Rehmannia Root Tuber Extract is rated possibly effective for chronic kidney disease — that's the strongest rating we hold.

For the other ingredients, the data shows insufficient reliable evidence to rate their effectiveness for aging skin, anal fissures, atherosclerosis, chronic fatigue, cirrhosis, migraine headache, cancer, dementia, diabetes, diabetic nephropathy, and diarrhea. This doesn't mean they don't work; it means the research supporting these uses isn't yet strong enough to rate them.

The evidence, ingredient by ingredient Peony Poria Mushroom Asian Water Plantain Rehmannia

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 3 of the 4 matched ingredients.
  • Pregnancy & breastfeeding safety ratings cover 4 of 4.
  • General safety write-ups exist for 4 of 4.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Tree Peony Root Bark Extract is generally well tolerated for short-term use, but high-quality safety data are limited. The most common side effects reported orally are abdominal distension, loss of appetite, diarrhea, nausea, and general stomach discomfort.

In one study, diarrhea occurred in 5% of participants taking a peony product at a high dose for 24 weeks, versus 1% on placebo. Poria Mushroom Extract and Asian Water Plantain Rhizome Extract are also generally well tolerated in traditional use, though human safety data are limited.

Allergic reactions to poria have been reported rarely. Pregnancy and breastfeeding: we do not have enough safety data for any of these ingredients during pregnancy, so they should be avoided.

The same applies to breastfeeding — there isn't reliable safety information for any of them while nursing.

Side effects, ingredient by ingredient Peony Poria Mushroom Asian Water Plantain Rehmannia

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 4 of the 4 matched ingredients can interact with medications — Peony, Poria Mushroom, Asian Water Plantain, Rehmannia.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: anticoagulant / antiplatelet drugs; diabetes medications.
  • For scale: 1,383 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Check before taking YinVive if you use blood thinners or antiplatelet drugs — peony may increase bleeding risk. Also flag any medications metabolized by your liver's CYP1A2 or CYP3A4 enzymes, estrogen-based medications or hormonal birth control, sedatives or sleep aids, anticholinergic or cholinergic drugs (which affect nerve signaling), antihypertensive drugs (blood pressure medications), antidiabetes medications, and kidney-damaging drugs.

Use the search tool below to check your specific medications.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFormula with limited ingredient disclosure with no established evidence rating for its marketed use. Moderate medication interactions have been identified, and safety information is well characterized.

YinVive is a traditional formula with limited research backing most of its claims. If you take blood thinners, liver-metabolized drugs, estrogen-based medications, sedatives, or drugs that affect the kidneys, you need to talk to your pharmacist or doctor before starting this product.

Pregnant and breastfeeding women should avoid it. If none of those apply to you, run your exact medications through the interaction checker on this page.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 4 of 6 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Nov 22, 2024.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about YinVive, straight from the product label.

Brand ActiveHerb
Barcode (UPC) 817967012881
Net contents 80 Veggie Capsule(s)
Market status On market
Date entered into DSLD Nov 22, 2024
DSLD ID 320327
Product type Botanical
Supplement form Capsule
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Vegan, Vegetarian, Adult (18 - 50 Years), Gluten Free, Dairy Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for YinVive by ActiveHerb, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
2 Capsule(s)
Maximum serving Sizes:
2 Capsule(s)
Servings per container
40
UPC/BARCODE
817967012881
IngredientAmount% DV
Proprietary Blend Extract662 mg--
Asiatic Dogwood fruit without seed extract0 NP--
Tree Peony Root Bark Extract0 NP--
Chinese Yam rhizome extract0 NP--
Poria Sclerotium Extract0 NP--
Asian Water Plantain Rhizome Extract0 NP--
Rehmannia Root Tuber Extract, Cured0 NP--

Other ingredients: Hypromellose, Dextrin, Magnesium Stearate

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Formulation

YinVive is an herbal supplement well known to nourish Yin of the Yin-Yang energy. This time-tested herbal formula may help support, adrenal function, back function and sexual wellness.

No pharmaceuticals. Heavy metals tested.

Supports yin energy Extra strength

V Vegan

GF Gluten-free

Formula

YinVive is made from water extracts of authentic herbs. Minimal fillers.

Each capsule contains 2,100 mg dry herb equivalent.

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

FDA Statement of Identity

Herbal Dietary Supplement

Suggested/Recommended/Usage/Directions

Suggested Use: Take two capsules 2 to 3 times daily. Allow at least 4 weeks of daily use before expecting noticeable results.

Precautions

Warning: Consult a healthcare professional before use if you are on other medicines.

Keep out of reach of children.

See for yourself

YinVive by ActiveHerb label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

What’s inside

The Ingredients in YinVive by ActiveHerb

These are the 6 active ingredients this product is made of. Select any to open its full monograph.

Serving size2 Capsule(s) Dosage formCapsule Servings per container40 Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

Proprietary Blend Extract

662 mg per serving

Other (inactive) ingredients: Hypromellose, Dextrin, Magnesium Stearate. These complete the product’s ingredient list but are not active constituents.

Interaction report

YinVive by ActiveHerb Drug Interactions

Want to check YOUR meds against YinVive?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

Go to the checker
1,382Drugs
1,251 Moderate 131 Minor

Each ingredient & the kinds of drugs it affects

For each ingredient in YinVive with known interactions, here are the types of medications they can affect. Open any type for the detail — or search your exact drug in the checker above.

Tree Peony Root Bark Extract7 drug types · 811 drugs

Anticoagulant/Antiplatelet Drugs

Theoretically, combining peony with anticoagulant or antiplatelet drugs might increase the risk of bleeding.
In vitro research suggests that peony might have antiplatelet, anticoagulant, and antithrombotic effects.

Likelihood Possible Evidence D
Clozapine (Clozaril)

Theoretically, peony might increase the levels and clinical effects of clozapine.
In vitro research shows that peony suppresses the metabolism of clozapine via weak-to-moderate inhibitory effects on cytochromes P450 (CYP) 1A2 and CYP3A4. This effect has not been reported in humans.

Likelihood Possible Evidence D
Contraceptive Drugs

Theoretically, peony might interfere with contraceptive drugs due to competition for estrogen receptors.
In vitro and animal research shows that peony extract has estrogenic activity. Concomitant use might also increase the risk for estrogen-related adverse effects.

Likelihood Possible Evidence D
Cytochrome P450 1A2 (Cyp1A2) Substrates

Theoretically, use of peony may increase the levels and clinical effects of drugs metabolized by CYP1A2.
In vitro research shows that peony suppresses the metabolism of clozapine via weak-to-moderate inhibitory effects on CYP1A2 and CYP3A4. This effect has not been reported in humans.

Likelihood Possible Evidence D
Cytochrome P450 3A4 (Cyp3A4) Substrates

Theoretically, use of peony may increase the levels and clinical effects of drugs metabolized by CYP3A4.
In vitro research shows that peony suppresses the metabolism of clozapine via weak-to-moderate inhibitory effects on CYP1A2 and CYP3A4. This effect has not been reported in humans.

Likelihood Possible Evidence D
Estrogens

Theoretically, concomitant use of large amounts of peony might interfere with hormone replacement therapy and/or increase the risk for estrogen-related adverse effects.
In vitro and animal research shows that peony extract has estrogenic activity. Theoretically, peony might compete for estrogen receptors and/or cause additive estrogenic effects.

Likelihood Possible Evidence D
Phenytoin (Dilantin)

Theoretically, peony might reduce the levels and clinical effects of phenytoin.
Animal research shows that taking peony root reduces levels of phenytoin. Some researchers suggest that peony root might affect cytochrome P450 (CYP) 2C9, which metabolizes phenytoin. However, preliminary research in humans shows that peony root does not alter levels of losartan (Cozaar), which is also metabolized by CYP2C9.

Likelihood Probable Evidence D

Poria Sclerotium Extract3 drug types · 417 drugs

Anticholinergic Drugs

Theoretically, poria mushroom might decrease the clinical effects of anticholinergic drugs.
In animal research, poria mushroom essential oil reduces acetylcholinesterase activity. This interaction has not been shown in humans.

Likelihood Possible Evidence D
Cholinergic Drugs

Theoretically, poria mushroom might have additive effects when used with cholinergic drugs.
In animal research, poria mushroom essential oil reduces acetylcholinesterase activity. This interaction has not been shown in humans.

Likelihood Possible Evidence D
Cns Depressants

Theoretically, taking poria mushroom extract may enhance the therapeutic and adverse effects of sedatives.
Animal research shows that poria mushroom extract has sedative properties. This interaction has not been shown in humans.

Likelihood Possible Evidence D

Asian Water Plantain Rhizome Extract1 drug type · 355 drugs

Nephrotoxic Drugs

Studies on animals have shown that Asian water plantain extract, which contains triterpenoids, is generally safe at doses up to 1440 mg/kg orally daily and does not cause harm to the body. However, using a higher dose of the extract, at 33.3 grams/kg orally for 60 days, has been linked to kidney issues, as indicated by increased blood urea nitrogen levels, and enlargement of the liver and kidneys. Additionally, two components of Asian water plantain, alisol A and alisol B, when given in doses of 400 mg/kg daily and 500 mg/kg daily respectively for 6 months, have been found to increase the production of markers that suggest potential kidney damage from certain medications. While these findings suggest there is very little risk that Asian water plantain may interact with drugs that are harmful to the kidneys, caution is still advised if combined with known nephrotoxic drugs (source: pubmed.ncbi.nlm.nih.gov/28408883/)

Likelihood Unlikely Evidence A

Rehmannia Root Tuber Extract, Cured2 drug types · 258 drugs

Antidiabetes Drugs

Theoretically, rehmannia might increase the risk of hypoglycemia when taken with antidiabetes drugs.
Animal research shows that rehmannia may have hypoglycemic effects.

Likelihood Possible Evidence D
Antihypertensive Drugs

Theoretically, rehmannia might increase the risk of hypotension when taken with antihypertensive drugs.
Animal research shows that rehmannia may have hypotensive effects. Laboratory research shows that formulations of dried and processed rehmannia root inhibit angiotensin-converting enzyme (ACE).

Likelihood Possible Evidence D
The maker

Brand information

Manufacturer and brand details for YinVive, from the product label.

ActiveHerb

See all ActiveHerb products
Name
ActiveHerb Technology, Inc.
City
San Diego
State
CA
ZipCode
92121
Phone Number
(888) 805-4372
Pharmacist Counseling Corner

YinVive by ActiveHerb: Common Questions

Does YinVive by ActiveHerb interact with any medications?
Yes. Based on its ingredients, YinVive has a known interaction with 1,382 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
YinVive contains 6 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Can I take YinVive if I'm pregnant or breastfeeding?
No, the safety data are not sufficient for either pregnancy or breastfeeding. All the ingredients in this product lack enough reliable information to know they're safe during these times. Talk to your doctor or pharmacist for personalized advice.
What are the most common side effects?
The Tree Peony extract in YinVive most commonly causes stomach issues: bloating, loss of appetite, diarrhea, nausea, and general discomfort. One study found diarrhea in about 5% of people taking a high-dose peony product. Allergic reactions to the poria mushroom ingredient have been reported rarely.
Does YinVive actually work for what it claims?
The evidence isn't established in our data. Rehmannia, one ingredient, is rated possibly effective for chronic kidney disease, but the others lack sufficient research to rate their effectiveness for the conditions listed on the label.
Is YinVive safe to use long-term?
The safety data are limited. The peony extract is considered well tolerated for short-term use, but high-quality long-term safety information isn't available. Additionally, the Asian Water Plantain ingredient can stress the kidneys and liver if used at high doses or for extended periods.
What is Poria Mushroom Extract, and why is it in here?
Poria is a medicinal mushroom used in traditional Chinese medicine. It's included in YinVive as part of the formula, though specific effectiveness data for this product are not on file.
Why does one of the ingredients say 'cured'?
Rehmannia Root Tuber Extract is listed as 'cured' because the root is processed — dried and sometimes steamed — before being extracted. This is how it's traditionally prepared in Chinese medicine, and the processing may affect how the herb works.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if YinVive is safe with your meds?

Our pharmacists answer your medication & supplement questions — free.

Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

YinVive label
Sources

Sources & How We Checked

YinVive's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 22 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Peony 15 references
  1. Chen LC, Chou MH, Lin MF, Yang LL. Effects of Paeoniae Radix, a traditional Chinese medicine, on the pharmacokinetics of phenytoin. J Clin Pharm Ther 2001;26:271-8. PubMed
  2. Guo TL, Zhou XW. [Clinical observations on the treatment of the gestational hypertension syndrome with Angelica and Paeonia powder]. Zhong Xi Yi Jie He Za Zhi 1986;6:714-6, 707.
  3. Xie HJ, Yasar U, Sandberg M, Rane A. Paeoniae Radix, a traditional Chinese medicine, and CYP2C9 activity. J Clin Pharm Ther 2002;27:229-30. . PubMed
  4. Harada M, Suzuki M, Ozaki Y. Effect of Japanese Angelica root and peony root on uterine contraction in the rabbit in situ. J Pharmacobiodyn 1984;7:304-11. PubMed
  5. Anon. Monograph. Peony (Paeonia spp). Alt Med Rev 2001;6:495-9.
  6. Bruynzeel DP. Contact Dermatitis Due to Paeonia (Peony). Contact Dermatitis 1989; 20:152-3..
  7. Bian, X., Xu, Y., Zhu, L., Gao, P., Liu, X., Liu, S., Qian, M., Gai, M., Yang, J., and Wu, Y. Prevention of maternal-fetal blood group incompatibility with traditional Chinese herbal medicine. Chin Med J (Engl.) 1998;111(7):585-587.
  8. Wong, A. L. and Chan, T. Y. Interaction between warfarin and the herbal product quilinggao. Ann Pharmacother 2003;37(6):836-838.
  9. Cai Y, Yuan Q, Xu K, et al. Assessment of the therapeutic effect of total glycosides of peony for juvenile idiopathic arthritis: a systematic review and meta-analysis. Evid Based Complement Alternat Med 2016;2016:8292486.
  10. Koo YK, Kim JM, Koo JY, et al. Platelet anti-aggregatory and blood anti-coagulant effects of compounds isolated from Paeonia lactiflora and Paeonia suffruticosa. Pharmazie 2010;65(8):624-8.
  11. Wang W, Tian DD, Zheng B, et al. Peony-glycyrrhiza decoction, an herbal preparation, inhibits clozapine metabolism via cytochrome P450s, but not flavin-containing monooxygenase in in vitro models. Drug Metab Dispos 2015;43(7):1147-53. PubMed
  12. Zhou Y, Jin L, Kong F, et al. Clinical and immunological consequences of total glucosides of paeony treatment in Sjögren's syndrome: A randomized controlled pilot trial. Int Immunopharmacol. 2016 Oct;39:314-319. doi: 10.1016/j.intimp.2016.08.006. PubMed
  13. Zhu Q, Qi X, Wu Y, Wang K. Clinical study of total glucosides of paeony for the treatment of diabetic kidney disease in patients with diabetes mellitus. Int Urol Nephrol. 2016 Nov;48(11):1873-1880. doi: 10.1007/s11255-016-1345-5. PubMed
  14. Xu Y, Li X, Chen T, et al. Radix Paeoniae Alba increases serum estrogen level and up-regulates estrogen receptor expression in uterus and vagina of immature/ovariectomized mice. Phytother Res. 2019;33(1):117-29. [RETRACTED].
  15. Liu X, Li X, Li X, et al. The efficacy and safety of total glucosides of peony in the treatment of primary Sjögren's syndrome: a multi-center, randomized, double-blinded, placebo-controlled clinical trial. Clin Rheumatol. 2019;38(3):657-64. Erratum i

See these in context on the Peony monograph →

Poria Mushroom 3 references
  1. McGuffin M, Hobbs C, Upton R, Goldberg A, eds. American Herbal Products Association's Botanical Safety Handbook. Boca Raton, FL: CRC Press, LLC 1997.
  2. Kim H, Park I, Park K, Park S, Kim YI, Park BG. The positive effects of Poria cocos extract on quality of sleep in insomnia rat models. Int J Environ Res Public Health 2022;19(11):6629. PubMed
  3. Lv Q, Di X, Bian B, Li K, Guo J. Neuroprotective effects of Poria cocos (Agaricomycetes) essential oil on Aß1-40-induced learning and memory deficit in rats. Int J Med Mushrooms 2022;24(10):73-82.

See these in context on the Poria Mushroom monograph →

Asian Water Plantain 1 reference
  1. Yuen MF, Tam S, Fung J, Wong DK, Wong BC, Lai CL. Traditional Chinese medicine causing hepatotoxicity in patients with chronic hepatitis B infection: a 1-year prospective study. Aliment Pharmacol Ther. 2006 Oct 15;24(8):1179-86. PubMed

See these in context on the Asian Water Plantain monograph →

Rehmannia 3 references
  1. Zhang R, Zhou J, Jia Z, et al. Hypoglycemic effect of Rehmannia glutinosa oligosaccharide in hyperglycemic and alloxan-induced diabetic rats and its mechanism. J Ethnopharmacol 2004;90:39-43. PubMed
  2. Zhang RX, Li MX, Jia ZP. Rehmannia glutinosa: review of botany, chemistry and pharmacology. J Ethnopharmacol 2008;117(2):199-214. PubMed
  3. Chao CH, Hsu JL, Chen MF, et al. Anti-hypertensive effects of Radix Rehmanniae and its active ingredients. Nat Prod Res. 2020;34(11):1547-1552.

See these in context on the Rehmannia monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

Keep exploring