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Dietary supplement

Zeaxanthin with Lutein Ingredients & Drug Interactions

by BIOVEA

Zeaxanthin with Lutein label
See full label image
Softgel Capsule Category: Other Combinations
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 9, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Zeaxanthin with Lutein against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Zeaxanthin with Lutein is a dietary supplement by BIOVEA with 2 active ingredients. Its ingredients are commonly taken for eye health, age-related macular degeneration, cataract prevention.Based on those ingredients, 86 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Zeaxanthin. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

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Check Your Meds Against Zeaxanthin with Lutein by BIOVEA

Ask about any prescription or over-the-counter medication and we check it for interactions with Zeaxanthin with Lutein by BIOVEA — and tell you which ingredient is responsible.

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HelloPharmacist Scorecard of Zeaxanthin with Lutein by BIOVEA

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Jul 11, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 2 of its 2 active ingredients.
  • No proprietary blends here — you can verify the dose of every single component.

This product has 2 active ingredients: lutein and zeaxanthin, both carotenoids found naturally in the eye. They work together to support the health of the macula, the central part of the retina responsible for sharp vision.

The softgel also contains inactive ingredients—gelatin, purified water, glycerin, beeswax, and caramel powder—which help deliver the active compounds.

Does it work?

Moderate evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Moderate

Some clinical evidence supports this product's ingredients for its stated purpose, but it isn't conclusive.

Why this rating?
  • The label markets this product for: eye health and macular support.
  • We looked for evidence on: Age-related macular degeneration (AMD), Asthenopia (eye strain), Cataracts, Central serous retinopathy, Choroideremia, Diabetic retinopathy — and 4 related terms.
  • The strongest evidence on file: Lutein is rated "Possibly Effective" for Age-related macular degeneration (AMD) (Natural Medicines).
  • Also on file: Lutein is rated "Possibly Effective" for Cataracts.
  • Also on file: Zeaxanthin is rated "Possibly Effective" for Age-related macular degeneration (AMD).

Lutein is possibly effective for age-related macular degeneration (AMD) and cataracts. Zeaxanthin is also possibly effective for AMD.

For other conditions in the facts—retinitis pigmentosa, retinopathy of prematurity, bronchopulmonary dysplasia, and zeaxanthin's use in cognitive decline, Alzheimer's disease, asthma, and breast cancer—the evidence is either insufficient to rate or not established. Talk with your doctor about whether this product fits your specific eye health needs.

The evidence, ingredient by ingredient Lutein Zeaxanthin

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 2 matched ingredients.
  • Pregnancy & breastfeeding safety ratings cover 2 of 2.
  • General safety write-ups exist for 2 of 2.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Both lutein and zeaxanthin are generally well tolerated at typical supplement doses. Lutein has been studied up to 20 mg daily without adverse effects reported.

For pregnancy and breastfeeding, both ingredients are rated Likely Safe; however, the safety data on concentrated supplement doses (rather than food sources) is limited, so it's wise to check with your doctor or pharmacist before use during these periods.

Side effects, ingredient by ingredient Lutein Zeaxanthin

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 2 matched ingredients can interact with medications — Zeaxanthin.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: diabetes medications.
  • For scale: 86 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

If you take antidiabetes drugs, check with your pharmacist before starting this product. Zeaxanthin may theoretically increase the risk of low blood sugar (hypoglycemia).

For all other medications, no interactions are documented for the ingredients we could check.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with some supporting evidence for its stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.

If you're concerned about age-related macular degeneration or cataracts, this product may be worth discussing with your eye doctor. If you take antidiabetes drugs, talk with your pharmacist first—there's a theoretical risk of low blood sugar.

Both ingredients are well tolerated, but pregnancy or breastfeeding decisions should be made with your healthcare provider.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 2 of 2 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Oct 23, 2019.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Zeaxanthin with Lutein, straight from the product label.

Brand BIOVEA
Barcode (UPC) 818423024769
Net contents 30 Softgel(s)
Market status On market
Date entered into DSLD Oct 23, 2019
DSLD ID 208092
Product type Other Combinations
Supplement form Softgel Capsule
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years), Gluten Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Zeaxanthin with Lutein by BIOVEA, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Softgel(s)
Maximum serving Sizes:
1 Softgel(s)
Servings per container
30
UPC/BARCODE
818423024769
IngredientAmount% DV
Lutein12 mg--
Zeaxanthin4 mg--

Other ingredients: Gelatin, purified Water, Glycerin, Beeswax, Caramel powder

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Seals/Symbols

GMP Compliant Gluten free

Formulation

Gluten free

General Statements

Premium quality guaranteed 2001. BIOVEA is committed to product quality to support you and your family's wellness goals. Because we feel so strongly about the quality, potency and purity or our products, we 100% guarantee your satisfaction with every purchase.

Guaranteed premium quality

Eye health

Suggested/Recommended/Usage/Directions

Suggested Daily Intake: Take 1 softgel daily with a meal.

Precautions

Warning: If you are pregnant or lactating, consult a healthcare professional before using this product.

Keep out of reach of children.

Do not use this product if the safety seal on the bottle is broken.

Storage

Store in a cool, dry place.

FDA Disclaimer Statement

This statement has not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

FDA Statement of Identity

Dietary Supplement

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Zeaxanthin with Lutein by BIOVEA label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Zeaxanthin with Lutein label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Zeaxanthin with Lutein by BIOVEA

These are the 2 active ingredients this product is made of. Select any to open its full monograph.

Serving size1 Softgel(s) Dosage formSoftgel Capsule Servings per container30 Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

Lutein

No known
interactions
12 mg per serving

Lutein is a plant-based antioxidant pigment that concentrates in the eye, and the best evidence suggests it (often combined with zeaxanthin) may help...

Lutein monograph & interactions

Zeaxanthin

Interacts with
86 drugs
4 mg per serving

Zeaxanthin is a carotenoid pigment that, along with lutein, concentrates in the macula of the eye and may help support long-term eye health. The stron...

Zeaxanthin monograph & interactions

Other (inactive) ingredients: Gelatin, Purified Water, Glycerin, Beeswax, Caramel powder. These complete the product’s ingredient list but are not active constituents.

Interaction report

Zeaxanthin with Lutein by BIOVEA Drug Interactions

Want to check YOUR meds against Zeaxanthin with Lutein?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
86Drugs
86 Moderate

Ingredients driving the most interactions

Zeaxanthin 86

Individual Drug Interactions

The ingredients in Zeaxanthin with Lutein interact with 86 drugs. Click any drug to see the details.

1 of the 2 ingredients in Zeaxanthin with Lutein interact with drugs. Each result below shows which ingredient is responsible. Zeaxanthin

Each ingredient & the kinds of drugs it affects

For each ingredient in Zeaxanthin with Lutein with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Zeaxanthin1 drug type · 86 drugs

Antidiabetes Drugs

Theoretically, taking zeaxanthin with antidiabetes drugs might increase the risk of hypoglycemia.
In an animal diabetic model, zeaxanthin has hypoglycemic effects. However, population research has found that increasing intake of dietary zeaxanthin plus lutein does not decrease the risk of developing type 2 diabetes.

Likelihood Possible Evidence D
Zeaxanthin full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Zeaxanthin with Lutein, from the product label.

BIOVEA

See all BIOVEA products
Name
BIOVEA
Street Address
9160 E. Bahia Dr.
City
Scottsdale
State
AZ
ZipCode
85260
Web Address
www.biovea.com
Pharmacist Counseling Corner

Zeaxanthin with Lutein by BIOVEA: Common Questions

Does Zeaxanthin with Lutein by BIOVEA interact with any medications?
Yes. Based on its ingredients, Zeaxanthin with Lutein has a known interaction with 86 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Zeaxanthin with Lutein contains 2 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
What's the difference between lutein and zeaxanthin in this product?
They're both carotenoids that concentrate in the eye, especially the macula, and work together to support vision health. Lutein is possibly effective for AMD and cataracts; zeaxanthin is also possibly effective for AMD. The combo provides both.
Can I take this if I'm pregnant or breastfeeding?
Both lutein and zeaxanthin are rated Likely Safe in pregnancy and lactation. That said, safety data on concentrated supplement doses isn't as thorough as it is for food sources, so talk with your doctor or midwife before starting.
Are there any side effects?
Lutein and zeaxanthin are generally well tolerated at typical doses. Lutein has been studied at up to 20 mg daily without adverse effects. We have no reported adverse effects for zeaxanthin in our data.
I'm on diabetes medication—is this safe for me?
Zeaxanthin may theoretically increase the risk of low blood sugar when combined with antidiabetes drugs. It's not a guarantee, but it's important enough to discuss with your pharmacist or doctor before you start.
Does this actually prevent or treat macular degeneration?
Both ingredients are possibly effective for age-related macular degeneration (AMD), which means the evidence is promising but not definitive. Talk with your eye doctor about whether supplementing makes sense for your situation.
What are the inactive ingredients in this softgel?
The softgel contains gelatin, purified water, glycerin, beeswax, and caramel powder as inactive ingredients. If you have allergies or sensitivities to any of these, let us know.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Zeaxanthin with Lutein is safe with your meds?

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Zeaxanthin with Lutein label
Go deeper

The Full Monographs Behind Zeaxanthin with Lutein’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Lutein

Lutein is a plant-based antioxidant pigment that concentrates in the eye, and the best evidence suggests it (often combined with zeaxanthin) may help slow progression of age-related macular...

Read the full Lutein monograph → Herb & supplement monograph

Zeaxanthin

Interacts with 86 drugs

Zeaxanthin is a carotenoid pigment that, along with lutein, concentrates in the macula of the eye and may help support long-term eye health. The strongest evidence relates to slowing progres...

Read the full Zeaxanthin monograph →
Sources

Sources & How We Checked

Zeaxanthin with Lutein's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 6 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Lutein 2 references
  1. Brown L, Rimm EB, Seddon JM, et al. A prospective study of carotenoid intake and risk of cataract extraction in US men. Am J Clin Nutr 1999;70:517-24. PubMed
  2. Chasan-Taber L, Willett WC, Seddon JM, et al. A prospective study of carotenoid and vitamin A intakes and risk of cataract extraction in US women. Am J Clin Nutr 1999;70:509-16. PubMed

See these in context on the Lutein monograph →

Zeaxanthin 4 references
  1. Montonen J, Knekt P, Jarvinen R, Reunanen A. Dietary antioxidant intake and risk of type 2 diabetes. Diabetes Care 2004;27:362-6. PubMed
  2. Leermakers ET, Darweesh SK, Baena CP, et al. The effects of lutein on cardiometabolic health across the life course: a systematic review and meta-analysis. Am J Clin Nutr 2016;103(2):481-94. PubMed
  3. Kou L, Du M, Zhang C, Dai Z, Li X, Zhang B. The Hypoglycemic, Hypolipidemic, and Anti-Diabetic Nephritic Activities of Zeaxanthin in Diet-Streptozotocin-Induced Diabetic Sprague Dawley Rats. Appl Biochem Biotechnol 2017;182(3):944-955. PubMed
  4. Xu X, Zhao X, Berde Y, Low YL, Kuchan MJ. Milk and Plasma Lutein and Zeaxanthin Concentrations in Chinese Breast-Feeding Mother-Infant Dyads With Healthy Maternal Fruit and Vegetable Intake. J Am Coll Nutr 2019;38(2):179-184. PubMed

See these in context on the Zeaxanthin monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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