FDA-filed SPL labeling · retrieved through openFDA

Calcium Carbonate / Famotidine / Magnesium Hydroxide

A chewable combination of two antacids (calcium carbonate and magnesium hydroxide) and an acid reducer (famotidine) used to relieve heartburn associated with acid indigestion and sour stomach.

Brand names Pepcid CompleteDual Action Completeacid reducer plus antacidAcid Reducer Completeleader acid reducer complete +11 more
Drug class ⓘ Histamine-2 Receptor Antagonist
OTC Forms 2 Route Oral
Dr. Brian Staiger, PharmD, BCPS
Reviewed by Last reviewed Jul 10, 2026
🧬 Where this information comes from Click to expand

The clinical label records used on this page are FDA-filed Structured Product Labeling (SPL) retrieved through openFDA. We identified 52 clinical label sets within the page’s selected clinical scope after exact ingredient or ingredient-combination matching and applicable route/form matching. Forms, routes, brands, labelers, strengths, and NDC product-record counts are built separately from matching FDA National Drug Code Directory records. The linked DailyMed document is a representative official source for verification, not the page’s only clinical source. View the linked label on DailyMed →

At a glance
Linked label effectiveJan 25, 2024
Clinical labels in scope ⓘ52
AvailabilityOTC
Earliest approval/marketing year ⓘ2008
FDA-listed product records ⓘ105
Boxed warningNone found in compared labels
How we combine label and product data →
✓No current FDA shortage listed · checked Sep 28, 2026
⭐ Calcium Carbonate / Famotidine / Magnesium Hydroxide at a glance The quick version — the full detail is in the Patient Information Guide below.
💊
HelloPharmacist Editorial Team Bottom Line
This chewable tablet combines two antacids and an acid reducer to give fast relief of heartburn, acid indigestion, and sour stomach. Chew it fully — don't swallow whole — and use no more than 2 tablets in 24 hours. If your heartburn keeps coming back or lasts beyond 14 days, check with your doctor, as it could point to something more serious.

📖 Calcium Carbonate / Famotidine / Magnesium Hydroxide: Patient Information Guide

A plain-language walkthrough of Calcium Carbonate / Famotidine / Magnesium Hydroxide — what it treats, how it works, how it’s taken, side effects, warnings and interactions. Tap any section to expand it.

🎯What it's used for▾

This combination chewable tablet is used to relieve heartburn associated with acid indigestion and sour stomach.

  • Relieves heartburn linked to acid indigestion and sour stomach — supported across CareOne Acid Reducer Complete, Basic Care Dual Action Complete, complete, and related chewable tablet products
💊How it's taken▾

Chew one tablet fully before swallowing — never swallow it whole. Adults and children 12 and older may take one tablet as needed to relieve symptoms.

  • Maximum: 2 chewable tablets in any 24-hour period
  • Children under 12: ask a doctor first
  • Do not use for more than 14 days unless directed by a doctor
🤒Side effects — in detail▾

The FDA labels for this combination do not list specific common side effects, but there are important warning signs to watch for.

  • Heartburn that continues or worsens after taking this product
  • Trouble or pain swallowing food
  • Nausea or vomiting
  • Stomach pain

Stop use and get medical help right away if you vomit blood or notice bloody or black stools, or if you experience chest pain with shortness of breath, sweating, or dizziness — these can be signs of a serious medical emergency.

⚠️Warnings & precautions▾
  • Serious symptoms mean stop and see a doctor: Vomiting blood, bloody or black stools, and trouble swallowing food may signal a serious condition — do not use this product and get medical help right away.
  • Heart attack warning signs: Chest or shoulder pain with shortness of breath, sweating, lightheadedness, or pain spreading to the arms, neck, or shoulders requires emergency care — do not assume it's heartburn.
  • Long-lasting or recurring heartburn: If heartburn has lasted more than 3 months, or you need this product for more than 14 days, talk to your doctor — it could point to a more serious underlying condition.
  • Other symptoms that need a doctor's evaluation before use: Frequent chest pain, frequent wheezing with heartburn, unexplained weight loss, nausea, vomiting, or stomach pain.
  • Allergy: Do not use if you are allergic to famotidine or other acid reducers.
  • Kidney disease: Ask a doctor before use if you have kidney disease.
  • Pregnancy and breastfeeding: Ask a health professional before use.
🔀What it interacts with▾

This product can interact with other medications, so check with a pharmacist or doctor if you take prescription drugs.

  • Other acid reducers: Do not use this product together with other acid reducers — combining them is not recommended.
  • Prescription drugs: Both antacids and acid reducers can affect how certain prescription medicines are absorbed or work — always ask a doctor or pharmacist before combining.

This is not a complete list of interactions. Always talk with your doctor or pharmacist before starting, stopping, or changing any medication.

📋Before taking it▾
  • Do not use if you are allergic to famotidine or any other acid reducer
  • Ask a doctor before use if you have had heartburn lasting more than 3 months
  • Ask a doctor before use if you have kidney disease
  • Ask a doctor before use if you have frequent chest pain, frequent wheezing (especially with heartburn), unexplained weight loss, nausea, vomiting, or stomach pain
  • Ask a doctor or pharmacist before use if you take any prescription medication
  • If you are pregnant or breastfeeding, ask a health professional before use
  • Do not give to children under 12 without first asking a doctor
🚑If you take too much▾

In case of overdose, get medical help or contact a Poison Control Center right away at 1-800-222-1222. Keep this and all medicines out of reach of children.

📦How to store it▾

store at 20°-25°C (68°-77°F) protect from moisture do not use if foil inner seal imprinted with "Sealed For Your Safety" is broken or missing

📄 Written from Calcium Carbonate / Famotidine / Magnesium Hydroxide’s FDA-approved label information, summarized in plain language with AI, and reviewed by our pharmacy team before publication. Every point is grounded in that labeling — nothing is invented. How we use AI →

🩺 Pharmacist Counseling Corner

Quick, plain-English answers to the questions patients ask most about Calcium Carbonate / Famotidine / Magnesium Hydroxide — the kind of thing our pharmacy team would talk through with you at the counter.

What exactly does this tablet do — how is it different from a regular antacid? ▾
This tablet combines two antacids — calcium carbonate and magnesium hydroxide — with famotidine, an acid reducer. The antacids work quickly to neutralize acid that's already in your stomach, while famotidine helps reduce how much acid your stomach produces. Together, they're designed to tackle heartburn from two angles. A plain antacid only does the first part.
Do I have to chew it, or can I just swallow it? ▾
You do need to chew it completely before swallowing — that's important. Don't swallow the tablet whole. Chewing it first is part of how it works and how it's meant to be used safely.
How many can I take in a day? ▾
The limit is 2 chewable tablets in any 24-hour period. If you find you're still reaching for this product after 14 days, that's a sign you should check in with your doctor — it could mean something more is going on.
Are there any warning signs I should take seriously right away? ▾
Yes — a few things should make you stop and seek medical help immediately. If you vomit blood or notice bloody or black stools, see a doctor right away. Chest or shoulder pain with shortness of breath, sweating, or pain spreading to your arms or neck could be signs of a heart attack, not heartburn — call 911. Don't assume these symptoms are just indigestion.
Can I take this if I'm on other prescription medications? ▾
Possibly, but check first. Both antacids and acid reducers can interact with certain prescription drugs — they can affect how well those medicines are absorbed by your body. Run it by your pharmacist or doctor before combining this with anything you're already taking on prescription.
Is it safe to use during pregnancy? ▾
The label says to ask a health professional before using this product if you're pregnant or breastfeeding. It's always a good idea to check with your OB or midwife before taking any over-the-counter medicine during pregnancy, just to make sure it's the right choice for your situation.
Is Calcium Carbonate / Famotidine / Magnesium Hydroxide available over the counter? ▾
Yes — Calcium Carbonate / Famotidine / Magnesium Hydroxide is available over the counter (without a prescription) in at least some forms, according to its FDA labeling. Follow the package directions and ask your pharmacist if you're unsure which product is right for you.
When was Calcium Carbonate / Famotidine / Magnesium Hydroxide first available? ▾
Calcium Carbonate / Famotidine / Magnesium Hydroxide has been available in the United States since at least 2008, based on FDA approval history (Drugs@FDA) and product marketing records.
Who makes Calcium Carbonate / Famotidine / Magnesium Hydroxide? ▾
Calcium Carbonate / Famotidine / Magnesium Hydroxide is supplied by 34 manufacturers listed in the FDA NDC Directory, including Lil' Drug Store Products, Inc., Kenvue Brands LLC, Walgreen Company.

💬 Answers drafted from Calcium Carbonate / Famotidine / Magnesium Hydroxide’s FDA-approved label information, summarized in plain language with AI, and reviewed by our pharmacy team before publication. Grounded in that labeling — nothing is made up. How we use AI →

🧰 Keep exploring

💊 How Calcium Carbonate / Famotidine / Magnesium Hydroxide comes

Calcium Carbonate / Famotidine / Magnesium Hydroxide is available in 2 forms. Different forms and brands can have different approved uses, doses, schedules, and directions. Follow the instructions for your exact product, and do not switch forms without guidance from your prescriber or pharmacist.

Chewable tablet

By mouth
Brands Acid Reducer Complete Acid Reducer Plus Antacid Basic Care Dual Action Complete CareOne Acid Reducer Complete Complete Acid Reducer Dual Action Complete Equaline Complete Equate Acid Reducer Complete Good Neighbor Pharmacy Dual Action Complete Good Sense Dual Action Complete Health Mart Dual Action Complete Leader Acid Reducer Complete Pepcid Complete Signature Care Acid Reducer Complete Topcare Dual Action Complete Up And Up Famotidine Complete
How this form is used
What it may be used for
  • Relieves heartburn associated with acid indigestion and sour stomach
Important instructions
  • Chew the tablet completely before swallowing — do not swallow whole
  • Adults and children 12 and older: chew 1 tablet to relieve symptoms
  • Do not use more than 2 chewable tablets in any 24-hour period
  • Children under 12 years: ask a doctor before use
Available strengths 5 strengths
104 FDA-listed product records ⓘ

📊 Calcium Carbonate / Famotidine / Magnesium Hydroxide across the U.S. market

How Calcium Carbonate / Famotidine / Magnesium Hydroxide appears in the FDA’s National Drug Code Directory — including its dosage forms, strengths, brand names, manufacturers, and FDA-listed product records. These are directory records, not sales or prescription volume.

2
Dose forms ⓘ
34
Manufacturers
25
Brand names
105
FDA-listed product records ⓘ
2008
First marketed ⓘ

FDA-listed product records by dose form (tablet variants merged) — FDA National Drug Code Directory. Record counts are not sales or prescription volume.

Lil' Drug Store Products, Inc.8%
Kenvue Brands LLC7%
Walgreen Company5%
Cardinal Health 110, LLC. dba Leader5%
CVS Pharmacy5%
Safeway5%
Other makers67%

Share of FDA-listed product records by manufacturer — FDA National Drug Code Directory. Record counts are not sales or prescription volume.

📈 How widely Calcium Carbonate / Famotidine / Magnesium Hydroxide is used

A general measure of how commonly Calcium Carbonate / Famotidine / Magnesium Hydroxide is prescribed, based on Medicaid — one of the largest public drug programs. The figure below is prescriptions filled in Q1–Q4 2025, summed across every form and brand of the drug.

Think of this as a proxy for how widely Calcium Carbonate / Famotidine / Magnesium Hydroxide is used, drawn from freely available public data. Medicaid is just one program — these numbers don’t include Medicare, other government coverage, or commercial and cash-pay prescriptions, so real-world use is higher than what’s shown here.

330
Medicaid prescriptions filled (Q1–Q4 2025)
$7,360 gross Medicaid reimbursement (before mandatory rebates — net cost is lower)

How commonly is Calcium Carbonate / Famotidine / Magnesium Hydroxide prescribed? Of the 1,597 medications we measure, Calcium Carbonate / Famotidine / Magnesium Hydroxide ranks #1,409 by Medicaid prescriptions — more than 12% of them.

Where Calcium Carbonate / Famotidine / Magnesium Hydroxide ranks among the drugs we measure · Q1–Q4 2025 · neighbors ±5

Utilization by Calcium Carbonate / Famotidine / Magnesium Hydroxide product

Pick a product to see its own Medicaid numbers. Each chip is one clinical product — a specific strength & dosage form as defined by RxNorm — with brand-name and generic versions combined.

calcium carbonate 800 MG / famotidine 10 MG / magnesium hydroxide 165 MG Chewable Tablet

330 Medicaid prescriptions (Q1–Q4 2025) 100% of Calcium Carbonate / Famotidine / Magnesium Hydroxide prescriptions shown $7,360 gross reimbursement (before rebates) ≈ $22 per prescription (gross)

Summed across the 3 of 139 listed NDC products with Medicaid activity — every brand and generic of this exact strength & form. RxNorm 283641

Shares are of the Medicaid prescriptions shown here. Product grouping follows RxNorm (the National Library of Medicine’s drug terminology), so “one product” means one strength & dosage form regardless of manufacturer. Dollar figures are gross Medicaid reimbursement before mandatory rebates — rebates (often large, especially for brand-name drugs) are confidential, so actual net cost to Medicaid is lower than shown.

Source: Medicaid State Drug Utilization Data (CMS), aggregated by generic ingredient — summed across every NDC (all brands, strengths, salt forms and dosage forms) of Calcium Carbonate / Famotidine / Magnesium Hydroxide, and across all states and both fee-for-service and managed-care claims. A general popularity signal; it excludes Medicare, commercial insurance and cash prescriptions, so it is not total U.S. use. Based on the 3 of 139 listed Calcium Carbonate / Famotidine / Magnesium Hydroxide NDCs with Medicaid activity.

🔍 Compare Calcium Carbonate / Famotidine / Magnesium Hydroxide products

A representative set of FDA-listed product records for Calcium Carbonate / Famotidine / Magnesium Hydroxide — across manufacturers, strengths, and dosage forms, grouped by form with each product’s manufacturer and how the FDA approved it. The same medicine may be made and packaged by different companies, so a single drug can have many directory entries. (It’s also why a refill can look different — a new shape, color, or box — even though it contains the same medication.)

Showing 105 of 105 products — FDA National Drug Code Directory. See every product, package size and price: browse all 105 Calcium Carbonate / Famotidine / Magnesium Hydroxide NDCs →

RxNorm Concept Web — From Ingredient to Every Form and Strength

This page starts with one exact multiple-ingredient concept (MIN). The branches below show its dose-form concepts (SCDF), then the available clinical drug and strength concepts (SCD). A product with a different ingredient combination belongs on a different page.

Multiple ingredients (MIN) Calcium Carbonate / Famotidine / Magnesium Hydroxide RxCUI 691005 1 dose form · 1 strength

Look up RxCUI 691005 in the RxCUI Atlas →

RxNorm is the U.S. National Library of Medicine’s normalized drug vocabulary. Its concept hierarchy can include forms that are not currently marketed; the status on each branch compares that concept with current FDA listings. RxCUIs identify vocabulary concepts, not individual packages or manufacturers.

🏷️ Sold under these brand names

Pepcid Complete Dual Action Complete acid reducer plus antacid Acid Reducer Complete leader acid reducer complete topcare dual action complete CareOne Acid Reducer Complete Good Sense Dual Action Complete Equate Acid Reducer Complete Good Neighbor Pharmacy Dual Action Complete equaline complete Signature Care Acid Reducer Complete up and up famotidine complete health mart dual action complete basic care dual action complete Complete Acid Reducer

🏭 Manufacturers & labelers

Lil' Drug Store Products, Inc. 8 Kenvue Brands LLC 7 Walgreen Company 5 Cardinal Health 110, LLC. dba Leader 5 CVS Pharmacy 5 Safeway 5 L. Perrigo Company 5 Topco Associates LLC 4 H E B 4 Target Corporation 4 Meijer Distribution Inc 4 American Sales Company 4 Rite Aid Corporation 4 Johnson & Johnson Consumer Inc. 3 Strategic Sourcing Services LLC 3 Johnson & Johnson Consumer Inc., McNeil Consumer Healthcare Division 3 JC World Bell Wholesale Co., Inc. 3 Wal-Mart Stores Inc 3 Amerisource Bergen 3 R J General Corporation 2 United Natural Foods, Inc. dba UNFI 2 Cvs Woonsocket Prescription Center, Incorporated 2 Kroger Company 2 Amazon.com Services LLC 2

…and 10 more on the FDA NDC directory.

RxNorm drug class

Calcium Carbonate / Famotidine / Magnesium Hydroxide belongs to the Calcium compounds class.

Drug family (ATC) Calcium compounds, Calcium

Classified by RxNorm RxClass — the U.S. National Library of Medicine's standardized drug-classification service (Established Pharmacologic Class from the FDA, the ATC drug family from the WHO, and mechanism of action). Reference only, not medical advice.

🔬 Where this comes from

Core label, product, RxNorm, safety, and utilization data on this page come from the sources identified below. AI-written, editorial, and licensed sections are labeled separately.

📄
FDA-filed drug labels (SPL) Uses, dosing, warnings & side effects from SPL records retrieved through openFDA; the linked representative set can be verified on DailyMed. ✓ Linked label effective Jan 25, 2024
🏭
Forms, brands & labelersAggregated from ingredient-matched FDA National Drug Code Directory product records for Calcium Carbonate / Famotidine / Magnesium Hydroxide.
📈
Real-world reportsThe FDA Adverse Event Reporting System (FAERS), served through openFDA.
🚨
Recalls & shortagesopenFDA drug-enforcement reports and the FDA drug-shortage database.
🧾 Clinical label set — FDA-filed SPL labels retained for Calcium Carbonate / Famotidine / Magnesium Hydroxide after exact ingredient or ingredient-combination matching and applicable route/form matching
Clinical labels in scope
52
NDC products indexed
105
Distinct labelers/manufacturers represented
34
Linked representative label ⓘ
Lil' Drug Store Products, Inc.
Linked label effective
Jan 25, 2024
Composite sections available
7
Linked SPL Set ID
d08984b8-ce03-9e95-e053-2995a90ae6f0
Linked SPL Document ID
0fcbbeb6-b37d-ca2c-e063-6394a90a23ea
Open the linked representative label on DailyMed ↗

How we combine label and product data

HelloPharmacist combines public FDA and NLM records; we don’t author the underlying clinical facts. We identified 52 FDA-filed SPL label sets within the page’s selected clinical scope after exact ingredient or ingredient-combination matching and applicable route/form matching. The representative label is the starting point for the displayed reference monograph; the 12 largest stored in-scope SPL records, which may include that representative, are compared section by section, and the longest available version of each section is retained. Forms, routes, brands, labelers, product-listed strengths, and product-record counts are aggregated separately from ingredient-matched FDA NDC Directory records; package records listed above are associated with the linked SPL; and the normalized concept hierarchy comes from NLM RxNorm.

For canonical ingredient pages, bounded product-attributed indication and administration excerpts may be added to the AI evidence, and the generator is instructed to preserve available product, brand, route, and form qualifiers instead of treating one label as universal. Where a section is identified as AI-written, its plain-language text is generated from bounded label evidence. New draft drug pages remain in the admin review queue before first publication. Lil' Drug Store Products, Inc. is the representative DailyMed label linked for verification and dates; it is not the sole source used for the page.

This is general education, not medical advice — always consult your doctor or pharmacist about your medications and any medical condition. For the exact wording of the linked representative label, view that label on DailyMed; some displayed composite sections may come from other in-scope SPL labels. Learn how we use AI and our data sources & update cadence.