Luliconazole Topical
Luliconazole is an antifungal cream used to treat common fungal skin infections including athlete's foot, jock itch, and ringworm.
🧬 Where this information comes from Click to expand
The clinical label records used on this page are FDA-filed Structured Product Labeling (SPL) retrieved through openFDA. We identified 2 clinical label sets within the page’s selected clinical scope after exact ingredient or ingredient-combination matching and applicable route/form matching. Forms, routes, brands, labelers, strengths, and NDC product-record counts are built separately from matching FDA National Drug Code Directory records. The linked DailyMed document is a representative official source for verification, not the page’s only clinical source. View the linked label on DailyMed →
📖 Luliconazole Topical: Patient Information Guide
A plain-language walkthrough of Luliconazole Topical — what it treats, how it works, how it’s taken, side effects, warnings and interactions. Tap any section to expand it.
🎯What it's used for▾
Luliconazole topical cream is an antifungal used to treat fungal skin infections. The following uses are supported for Luzu (luliconazole) Cream, 1%:
- Interdigital tinea pedis (athlete's foot between the toes) caused by Trichophyton rubrum or Epidermophyton floccosum
- Tinea cruris (jock itch) caused by Trichophyton rubrum or Epidermophyton floccosum
- Tinea corporis (ringworm) caused by Trichophyton rubrum or Epidermophyton floccosum
⚙️How it works▾
Luliconazole is an azole antifungal. It works by blocking an enzyme called lanosterol demethylase, which fungi need to produce ergosterol — a critical component of their cell membranes. When ergosterol levels drop, the fungal membrane is disrupted and the fungus cannot survive. This targeted action helps clear the infection from the skin.
💊How it's taken▾
Luzu Cream, 1% is applied directly to the affected skin and approximately 1 inch of the area surrounding it, once daily. The treatment length depends on the type of infection:
- Athlete's foot (interdigital tinea pedis): apply once daily for 2 weeks.
- Jock itch (tinea cruris) or ringworm (tinea corporis): apply once daily for 1 week.
Apply it at around the same time each day. Always follow your prescriber's specific instructions, and finish the full course even if your skin looks better sooner.
🤒Side effects — in detail▾
Luliconazole cream is generally very well tolerated. The most common side effects are:
- Skin reactions at the application site — such as redness, stinging, or irritation — affecting fewer than 1 in 100 people in clinical trials. Most reactions were mild.
If you notice severe skin irritation, worsening redness, or any unusual reaction at the application site, stop using the cream and contact your doctor.
⚠️Warnings & precautions▾
- For skin use only: Luzu Cream, 1% must not be used in or near the eyes, mouth, or vagina. If contact occurs, rinse the area thoroughly with water.
- Enzyme interaction concern in adolescents: Blood levels of luliconazole in teenagers may be high enough to affect how some other drugs are processed by the body — make sure your prescriber knows about all medications a teen is taking.
- Pregnancy and breastfeeding: There are no human safety data during pregnancy, and it is unknown whether luliconazole passes into breast milk. Discuss the risks with your doctor before using this cream if you are pregnant or nursing.
🔀What it interacts with▾
Although luliconazole is applied to the skin, a small amount is absorbed into the body and can affect how certain medications are processed.
- CYP2C19-metabolized drugs (adults): Luliconazole cream weakly inhibits the CYP2C19 enzyme in adults — which can raise blood levels of drugs processed by that enzyme. Tell your pharmacist about all your medications.
- CYP2C19-metabolized drugs (adolescents): In teenagers, absorption is higher and luliconazole may moderately inhibit CYP2C19 — a more significant concern if the teen takes other medications. A prescriber or pharmacist should review the full medication list.
This is not a complete list of interactions. Always talk with your doctor or pharmacist before starting, stopping, or changing any medication.
📋Before taking it▾
- Pregnancy: No human data exist on this cream's safety during pregnancy. Animal studies at high doses showed some effects on fetal development. Talk to your doctor before using it if you are pregnant.
- Breastfeeding: It is not known whether luliconazole passes into breast milk. Discuss the benefits and risks with your doctor.
- Children under 12: Safety and effectiveness have not been fully established in children under 12 years of age.
- Teenagers: Adolescents may absorb more luliconazole through the skin; this is especially relevant if they take other medications. A prescriber should be aware.
- Eyes, mouth, vagina: This cream is not meant for these areas — avoid contact and keep it on the skin only.
📡Pharmacodynamics — effects in the body▾
At normal treatment doses, Luliconazole Cream, 1% is not expected to have any meaningful effect on the heart's electrical activity (specifically, it is not expected to prolong the QTc interval to a clinically relevant extent).
🔬Pharmacokinetics — how your body processes it▾
Even though luliconazole is applied to the skin, measurable amounts do enter the bloodstream. In studies, people with athlete's foot absorbed less than those with jock itch — likely because the groin area absorbs more than the feet. Once absorbed, luliconazole binds very tightly to proteins in the blood (more than 99%), and blood levels build up slightly over the course of treatment. The amounts absorbed are small, but they are enough to potentially affect some liver enzymes that process other drugs.
📦How to store it▾
Store at 20° to 25°C (68° to 77°F); excursions permitted from 15° to 30°C (59° to 86°F) .
📄 Written from Luliconazole Topical’s FDA-approved label information, summarized in plain language with AI, and reviewed by our pharmacy team before publication. Every point is grounded in that labeling — nothing is invented. How we use AI →
Supplements & herbs that interact with Luliconazole Topical
23 supplements and herbal products have documented interactions with Luliconazole Topical in the licensed clinical database we use. Most are manageable — but your pharmacist should know about everything you take, including vitamins and herbals.
- Moderate · 22
- Minor · 1
Educational information from a licensed clinical database (Natural Medicines) — see our data sources & update cadence. Not medical advice: an interaction being documented does not mean it will happen to you; do not start or stop medications or supplements without professional guidance.
🩺 Pharmacist Counseling Corner
Quick, plain-English answers to the questions patients ask most about Luliconazole Topical — the kind of thing our pharmacy team would talk through with you at the counter.
What skin problems does luliconazole cream actually treat? ▾
How long do I need to keep using it before I see results? ▾
Is it okay to put this cream on any part of my body? ▾
What side effects should I expect — and what should make me call my doctor? ▾
Can I use this cream if I'm pregnant or breastfeeding? ▾
Does this cream interact with any other medications I might be taking? ▾
Is Luliconazole Topical available over the counter? ▾
When was Luliconazole Topical first available? ▾
Who makes Luliconazole Topical? ▾
💬 Answers drafted from Luliconazole Topical’s FDA-approved label information, summarized in plain language with AI, and reviewed by our pharmacy team before publication. Grounded in that labeling — nothing is made up. How we use AI →
🧰 Keep exploring
💊 How Luliconazole Topical comes
Luliconazole Topical is available in 1 form. Different forms and brands can have different approved uses, doses, schedules, and directions. Follow the instructions for your exact product, and do not switch forms without guidance from your prescriber or pharmacist.
Topical cream, ointment or gel
How this form is used
- Luzu Cream, 1% is used to treat interdigital tinea pedis (athlete's foot between the toes) caused by Trichophyton rubrum or Epidermophyton floccosum.
- Luzu Cream, 1% is used to treat tinea cruris (jock itch) caused by Trichophyton rubrum or Epidermophyton floccosum.
- Luzu Cream, 1% is used to treat tinea corporis (ringworm) caused by Trichophyton rubrum or Epidermophyton floccosum.
- Luzu Cream, 1%: apply a thin layer to the affected area and about 1 inch of the surrounding skin once daily.
- Luzu Cream, 1%: treat athlete's foot between the toes for 2 weeks; treat jock itch or ringworm for 1 week.
- Luzu Cream, 1% is for skin use only — do not apply to eyes, inside the mouth, or inside the vagina.
- Luzu Cream, 1%: apply at roughly the same time each day and follow your prescriber's instructions for the full course.
📊 Luliconazole Topical across the U.S. market
How Luliconazole Topical appears in the FDA’s National Drug Code Directory — including its dosage forms, strengths, brand names, manufacturers, and FDA-listed product records. These are directory records, not sales or prescription volume.
Share of FDA-listed product records by manufacturer — FDA National Drug Code Directory. Record counts are not sales or prescription volume.
📈 How widely Luliconazole Topical is used
A general measure of how commonly Luliconazole Topical is prescribed, based on Medicaid — one of the largest public drug programs. The figure below is prescriptions filled in Q1–Q3 2025, summed across every form and brand of the drug.
Think of this as a proxy for how widely Luliconazole Topical is used, drawn from freely available public data. Medicaid is just one program — these numbers don’t include Medicare, other government coverage, or commercial and cash-pay prescriptions, so real-world use is higher than what’s shown here.
How commonly is Luliconazole Topical prescribed? Of the 1,596 medications we measure, Luliconazole Topical ranks #1,549 by Medicaid prescriptions — more than 3% of them.
Utilization by Luliconazole Topical product
Pick a product to see its own Medicaid numbers. Each chip is one clinical product — a specific strength & dosage form as defined by RxNorm — with brand-name and generic versions combined.
luliconazole 10 MG/ML Topical Cream
Summed across the 1 of 3 listed NDC products with Medicaid activity — every brand and generic of this exact strength & form. RxNorm 1482684
Shares are of the Medicaid prescriptions shown here. Product grouping follows RxNorm (the National Library of Medicine’s drug terminology), so “one product” means one strength & dosage form regardless of manufacturer. Dollar figures are gross Medicaid reimbursement before mandatory rebates — rebates (often large, especially for brand-name drugs) are confidential, so actual net cost to Medicaid is lower than shown.
Source: Medicaid State Drug Utilization Data (CMS), aggregated by generic ingredient — summed across every NDC (all brands, strengths, salt forms and dosage forms) of Luliconazole Topical, and across all states and both fee-for-service and managed-care claims. A general popularity signal; it excludes Medicare, commercial insurance and cash prescriptions, so it is not total U.S. use. Based on the 1 of 3 listed Luliconazole Topical NDCs with Medicaid activity.
🔍 Compare Luliconazole Topical products
A representative set of FDA-listed product records for Luliconazole Topical — across manufacturers, strengths, and dosage forms, grouped by form with each product’s manufacturer and how the FDA approved it. The same medicine may be made and packaged by different companies, so a single drug can have many directory entries. (It’s also why a refill can look different — a new shape, color, or box — even though it contains the same medication.)
| Strength | Route | Manufacturer / Labeler | Category ⓘ | Details |
|---|---|---|---|---|
| 💊Topical cream, ointment or gel | ||||
| 10 mg/g | Topical | Bausch Health US, LLC × 2 listings | NDA | View NDC → |
| 10 mg/g | Topical | Oceanside Pharmaceuticals × 2 listings | NDA | View NDC → |
Showing 4 of 4 products — FDA National Drug Code Directory. See every product, package size and price: browse all 4 Luliconazole Topical NDCs →
📈 What people report — real-world data (FDA FAERS)
After a medicine reaches the market, patients, doctors and drugmakers can send the FDA reports of problems they think may be linked to it. Here’s what’s been reported for Luliconazole Topical — a signal of what to watch for, not proof the drug caused it.
Source: openFDA, from the FDA Adverse Event Reporting System (FAERS). These are voluntary reports — they don’t prove the drug caused the effect, and counts reflect how often something was reported, not how often it actually happens. Reports also often name the very problem the medicine is taken for — a common reason to file one is that the drug didn’t help — so for a pain reliever you may see “pain” high on the list; that points to why the report was filed, not to the drug causing the symptom. This counts every report that lists Luliconazole Topical in any role, so the total runs higher than the FDA’s official dashboard, which counts only cases where the drug is the suspect. For the authoritative figures, see the FDA FAERS Public Dashboard. Always talk to your pharmacist or doctor.
🏛️ The road to your pharmacy
How Luliconazole Topical went from FDA review to the pharmacy shelf — the key milestones in its regulatory journey.
Source: Drugs@FDA.
🚨 Recall history
A recall is when a specific batch of a medicine is pulled from the market — usually a manufacturing issue, not a problem with the drug itself. Class I is most serious, Class III least.
Source: openFDA drug enforcement (recall) reports.
RxNorm Concept Web — From Ingredient to Every Form and Strength
This page starts with one ingredient concept (IN). The branches below show its dose-form concepts (SCDF), then the available clinical drug and strength concepts (SCD). Combination products remain separate concepts with their own pages.
RxCUI 1482680 1 dose form · 1 strength
-
Dose form (SCDF) Topical Cream RxCUI 1482683In current FDA listingsClinical drug / strength (SCD) 10 MG/MLRxCUI 1482684
Look up RxCUI 1482680 in the RxCUI Atlas →
RxNorm is the U.S. National Library of Medicine’s normalized drug vocabulary. Its concept hierarchy can include forms that are not currently marketed; the status on each branch compares that concept with current FDA listings. RxCUIs identify vocabulary concepts, not individual packages or manufacturers.
📦 Supply & shortage status
Whether Luliconazole Topical is in short supply in the U.S. right now, plus any shortage history the FDA has on record. A shortage usually reflects a manufacturing or demand issue — not a safety problem with the drug.
Source: openFDA, from the FDA Drug Shortages database.
🏷️ Sold under these brand names
🏭 Manufacturers & labelers
RxNorm drug class
Luliconazole Topical belongs to the Azole Antifungal class.
Classified by RxNorm RxClass — the U.S. National Library of Medicine's standardized drug-classification service (Established Pharmacologic Class from the FDA, the ATC drug family from the WHO, and mechanism of action). Reference only, not medical advice.
🔬 Where this comes from
Core label, product, RxNorm, safety, and utilization data on this page come from the sources identified below. AI-written, editorial, and licensed sections are labeled separately.
How we combine label and product data
HelloPharmacist combines public FDA and NLM records; we don’t author the underlying clinical facts. We identified 2 FDA-filed SPL label sets within the page’s selected clinical scope after exact ingredient or ingredient-combination matching and applicable route/form matching. The representative label is the starting point for the displayed reference monograph; the 12 largest stored in-scope SPL records, which may include that representative, are compared section by section, and the longest available version of each section is retained. Forms, routes, brands, labelers, product-listed strengths, and product-record counts are aggregated separately from ingredient-matched FDA NDC Directory records; package records listed above are associated with the linked SPL; and the normalized concept hierarchy comes from NLM RxNorm.
Where a section is identified as AI-written, its plain-language text is generated from bounded label evidence. New draft drug pages remain in the admin review queue before first publication. Oceanside Pharmaceuticals is the representative DailyMed label linked for verification and dates; it is not the sole source used for the page.
This is general education, not medical advice — always consult your doctor or pharmacist about your medications and any medical condition. For the exact wording of the linked representative label, view that label on DailyMed; some displayed composite sections may come from other in-scope SPL labels. Learn how we use AI and our data sources & update cadence.