Nizatidine

Generic name: Pronounced as (ni za' ti deen)
Brand names
  • Axid®
  • Axid® AR
Click on drug name to hear pronunciation

Medical Content Reviewed By HelloPharmacist Staff

Last Revised - 12/15/2017

Nizatidine is used to treat and prevent the recurrence of ulcers and to treat other conditions where the stomach makes too much acid. Nizatidine also is used to treat or prevent occasional heartburn, acid indigestion, or sour stomach. It decreases the amount of acid made in the stomach. Nizatidine is available with and without a prescription.

This medication is sometimes prescribed for other uses; ask your doctor or pharmacist for more information.

Nizatidine comes as a tablet and capsule to take by mouth. It usually is taken once daily at bedtime or twice a day with or without food. Follow the directions on the package or on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand. Take nizatidine exactly as directed. Do not take more or less of it or take it more often than prescribed by your doctor.

If symptoms of heartburn, acid indigestion, or sour stomach last for longer than 2 weeks while taking nizatidine, stop taking it and call your doctor.

Before taking nizatidine,

  • tell your doctor and pharmacist if you are allergic to nizatidine or any other drugs.

  • tell your doctor and pharmacist what prescription and nonprescription medications you are taking, especially aspirin or antacids such as Maalox or Mylanta, and vitamins.

  • tell your doctor if you have or have ever had kidney or liver disease.

  • tell your doctor if you are pregnant, plan to become pregnant, or are breast-feeding. If you become pregnant while taking nizatidine, call your doctor.

Take the missed dose as soon as you remember it. However, if it is almost time for the next dose, skip the missed dose and continue your regular dosing schedule. Do not take a double dose to make up for a missed one.

  • Nizatidine may cause side effects. Tell your doctor if any of these symptoms are severe or do not go away:

    • headache

    • dizziness

    • drowsiness

    • constipation

    • diarrhea

    • stomach pain

    • runny nose

    • sneezing

    • coughing

    • sweating

  • If you have any of the following symptoms, call your doctor immediately:

    • skin rash

    • hives

    • itching

    • wheezing

    • difficulty breathing

  • If you experience a serious side effect, you or your doctor may send a report to the Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting program online (http://www.fda.gov/Safety/MedWatch) or by phone (1-800-332-1088).

Keep this medication in the container it came in, tightly closed, and out of reach of children. Store it at room temperature and away from excess heat and moisture (not in the bathroom).

It is important to keep all medication out of sight and reach of children as many containers (such as weekly pill minders and those for eye drops, creams, patches, and inhalers) are not child-resistant and young children can open them easily. To protect young children from poisoning, always lock safety caps and immediately place the medication in a safe location – one that is up and away and out of their sight and reach. http://www.upandaway.org

Unneeded medications should be disposed of in special ways to ensure that pets, children, and other people cannot consume them. However, you should not flush this medication down the toilet. Instead, the best way to dispose of your medication is through a medicine take-back program. Talk to your pharmacist or contact your local garbage/recycling department to learn about take-back programs in your community. See the FDA's Safe Disposal of Medicines website (http://goo.gl/c4Rm4p) for more information if you do not have access to a take-back program.

In case of overdose, call the poison control helpline at 1-800-222-1222. Information is also available online at https://www.poisonhelp.org/help. If the victim has collapsed, had a seizure, has trouble breathing, or can't be awakened, immediately call emergency services at 911.

Keep all appointments with your doctor.

Do not let anyone else take your medicine. Ask your pharmacist any questions you have about refilling your prescription.

It is important for you to keep a written list of all of the prescription and nonprescription (over-the-counter) medicines you are taking, as well as any products such as vitamins, minerals, or other dietary supplements. You should bring this list with you each time you visit a doctor or if you are admitted to a hospital. It is also important information to carry with you in case of emergencies.

Content provided by: AHFS® Patient Medication Information™. © Copyright, 2021. The American Society of Health-System Pharmacists