Ranitidine
Ranitidine is an acid-reducing medication used to treat and prevent conditions including duodenal ulcers, gastric ulcers, GERD, erosive esophagitis, and heartburn caused by acid indigestion.
🧬 Where this information comes from Click to expand
The clinical label records used on this page are FDA-filed Structured Product Labeling (SPL) retrieved through openFDA. We identified 13 clinical label sets within the page’s selected clinical scope after exact ingredient or ingredient-combination matching and applicable route/form matching. Forms, routes, brands, labelers, strengths, and NDC product-record counts are built separately from matching FDA National Drug Code Directory records. The linked DailyMed document is a representative official source for verification, not the page’s only clinical source. View the linked label on DailyMed →
Ranitidine (Zantac) is an H2 blocker, an acid reducer that stops histamine from telling stomach cells to make acid, and since arriving in the U.S. around 1983 it became one of the most familiar medicines for ulcers, GERD (acid reflux disease) and heartburn, available generically and over the counter. It was generally very well tolerated, with headache and constipation or diarrhea the side effects people noticed most. The thing to know now is that the FDA asked companies to pull all ranitidine from U.S. shelves because of NDMA, a contaminant that probably causes cancer, so do not take any you still have.
Clinical pearls
- Newer Zantac-branded products contain famotidine instead of ranitidine, so read the active ingredient line rather than the brand name.
- If you have leftover ranitidine, bring it to a drug take-back program instead of finishing the bottle.
- Ranitidine lowered absorption of ketoconazole, atazanavir and gefitinib, and any replacement acid reducer deserves the same check with your pharmacist.
- Anyone stopping ranitidine while on warfarin or glipizide should recheck clotting time or blood sugar, since levels can shift.
Patient information guide A plain-language walkthrough of Ranitidine, written from its FDA label.
What Ranitidine is used for
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Ranitidine is used to treat and prevent a range of conditions caused by excess stomach acid. The full set of supported uses across available products includes:
- Short-term treatment of active duodenal ulcers (ulcers in the upper small intestine)
- Maintenance therapy to prevent duodenal ulcers from coming back after healing
- Short-term treatment of active benign gastric ulcers (stomach ulcers)
- Maintenance therapy to prevent gastric ulcers from returning after healing
- Treatment of GERD (gastroesophageal reflux disease, or chronic acid reflux)
- Treatment of erosive esophagitis (acid-related damage to the lining of the esophagus), confirmed by endoscopy
- Maintenance of healing of erosive esophagitis
- Treatment of pathological hypersecretory conditions — rare disorders where the stomach overproduces acid, such as Zollinger-Ellison syndrome and systemic mastocytosis
- Acid Reducer and Acid Reducer 150 tablets: relief and prevention of heartburn associated with acid indigestion and sour stomach
How Ranitidine works
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Ranitidine is a competitive, reversible H2-receptor antagonist — meaning it blocks histamine from binding to H2 receptors on acid-producing cells in the stomach lining. When those receptors are blocked, the stomach gets the signal to produce far less acid. This reduction in acid helps ulcers heal, reduces irritation to the esophagus, and relieves heartburn. Ranitidine is not an anticholinergic agent and does not lower calcium levels in the blood.
Ranitidine reduces both daytime and nighttime acid secretion, as well as acid triggered by food, making it effective around the clock.
Ranitidine dosage
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Ranitidine is taken by mouth as a capsule, tablet, or liquid solution, or given by injection in medical settings. Oral forms can be taken with or without food — absorption is not significantly affected by meals or most antacids. Prescription forms are generally taken once or twice daily depending on the condition; your prescriber will determine the right schedule and duration for you. Over-the-counter tablets (such as Acid Reducer) are taken with a glass of water — to prevent heartburn, take one tablet 30 to 60 minutes before trigger foods or drinks, and use no more than twice daily. Always follow your prescription label or the OTC package directions, and do not use OTC products for more than 14 days without talking to a doctor.
Dosing details from the FDA-approved label
From the Ranitidine prescribing information (“Dosage and Administration”). Doses are set by your prescriber for your product, condition, kidney function and age — never change a dose on your own.
- Active Duodenal Ulcer
- 150 mg twice daily
- An alternative dosage of 300 mg once daily after the evening meal or at bedtime can be used for patients in whom dosing convenience is important
- Antacid should be given as needed for relief of pain
- Maintenance of Healing of Duodenal Ulcers
- 150 mg at bedtime
- Pathological Hypersecretory Conditions (Such as Zollinger-Ellison Syndrome)
- 150 mg twice a day
- In some patients it may be necessary to administer 150 mg doses more frequently
- Maximum: Dosages up to 6 g/day have been employed in patients with severe disease
- Dosages should be adjusted to individual patient needs and continue as long as clinically indicated
- Benign Gastric Ulcer
- 150 mg twice a day
- Maintenance of Healing of Gastric Ulcers
- 150 mg at bedtime
- GERD
- 150 mg twice a day
- Erosive Esophagitis
- 150 mg four times a day
- Maintenance of Healing of Erosive Esophagitis
- 150 mg twice a day
- Pediatric: Treatment of Duodenal and Gastric Ulcers
- 2 to 4 mg/kg twice daily
- Maximum: 300 mg/day
- Established in age-group 1 month to 16 years; insufficient information to make dosing recommendations for neonates less than 1 month
- Pediatric: Maintenance of Healing of Duodenal and Gastric Ulcers
- 2 to 4 mg/kg once daily
- Maximum: 150 mg/day
- Established in age-group 1 month to 16 years
Read the label’s full dosing text
DOSAGE AND ADMINISTRATION Active Duodenal Ulcer The current recommended adult oral dosage of Ranitidine Syrup (Ranitidine Oral Solution USP) for duodenal ulcer is 150 mg or 10 mL of oral solution (2 teaspoonfuls of oral solution equivalent to 150 mg of ranitidine) twice daily. An alternative dosage of 300 mg or 20 mL of oral solution (4 teaspoonfuls of oral solution equivalent to 300 mg of ranitidine) once daily after the evening meal or at bedtime can be used for patients in whom dosing convenience is important. The advantages of one treatment regimen compared to the other in a particular patient population have yet to be demonstrated (seeCLINICAL TRIALS: ACTIVE DUODENAL ULCER). Smaller doses have been shown to be equally effective in inhibiting gastric acid secretion in US studies, and several foreign trials have shown that 100 mg twice daily is as effective as the 150 mg dose. Antacid should be given as needed for relief of pain (see CLINICAL PHARMACOLOGY: PHARMACOKINETICS). Maintenance of Healing of Duodenal Ulcers The current recommended adult oral dosage is 150 mg or 10 mL of oral solution (2 teaspoonfuls of oral solution equivalent to 150 mg of ranitidine) at bedtime. Pathological Hypersecretory Conditions (such as Zollinger-Ellison syndrome) The current recommended adult oral dosage is 150 mg or 10 mL of oral solution (2 teaspoonfuls of oral solution equivalent to 150 mg of ranitidine) twice a day. In some patients it may be necessary to administer ranitidine 150 mg doses more frequently. Dosages should be adjusted to individual patient needs, and should continue as long as clinically indicated. Dosages up to 6 g/day have been employed in patients with severe disease. Benign Gastric Ulcer The current recommended adult oral dosage is 150 mg or 10 mL of oral solution (2 teaspoonfuls of oral solution equivalent to 150 mg of ranitidine) twice a day. Maintenance of Healing of Gastric Ulcers The current recommended adult oral dosage is 150 mg or 10 mL of oral solution (2 teaspoonfuls of oral solution equivalent to 150 mg of ranitidine) at bedtime. GERD The current recommended adult oral dosage is 150 mg or 10 mL of oral solution (2 teaspoonfuls of oral solution equivalent to 150 mg of ranitidine) twice a day.
Excerpted — the section continues on the label. Read the full Dosage and Administration section on DailyMed →
Ranitidine side effects
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Most people tolerate ranitidine well, but some side effects have been reported:
Common side effects
- Headache
- Constipation or diarrhea
- Nausea or vomiting
- Abdominal discomfort or pain
- Dizziness or drowsiness
- Insomnia
- Rash
- Rare: joint pain (arthralgias) or muscle pain (myalgias)
When to get medical help
- Get medical help right away if you have trouble or pain swallowing food, vomit blood, or see bloody or black stools — these can be signs of a serious condition.
- Call your doctor if you experience heartburn with lightheadedness, sweating, or dizziness.
- Seek emergency care for chest or shoulder pain with shortness of breath, sweating, or pain spreading to your arms, neck, or shoulders.
- Stop use and call your doctor if you have signs of liver problems: yellowing of the skin or eyes (jaundice), or unusual fatigue.
- Get medical help immediately for signs of a severe allergic reaction: hives, swelling of the face or throat, difficulty breathing, or anaphylaxis.
- Tell your doctor if you notice mental changes such as confusion, agitation, depression, or hallucinations — especially in older or seriously ill patients.
- Report any unusual bruising, bleeding, or frequent infections, which could signal rare blood count changes.
Serious but rare reactions include liver inflammation or failure, severe blood count changes (such as agranulocytosis or aplastic anemia), serious allergic reactions including anaphylaxis, and mental changes such as confusion or hallucinations — mostly in severely ill elderly patients. Stop taking ranitidine and get medical help immediately if any of these occur.
Ranitidine warnings and precautions
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- Allergic reaction: Do not use ranitidine if you are allergic to it or to other acid reducers. Seek emergency help for signs of anaphylaxis — swelling, difficulty breathing, severe rash.
- Serious GI symptoms: Trouble swallowing, vomiting blood, or black/bloody stools are warning signs of a serious condition — do not self-treat; see a doctor right away.
- Heart attack symptoms: Chest or shoulder pain with shortness of breath, sweating, or pain spreading to the arms or neck needs immediate emergency care — it is not heartburn until proven otherwise.
- Liver toxicity: Rare but serious liver reactions, including liver failure and death, have been reported. Stop ranitidine and seek care if you develop jaundice (yellowing of skin or eyes).
- Blood disorders: Rare cases of severely low white blood cell or platelet counts have occurred. Report unusual bruising, bleeding, or infections to your doctor.
- OTC use limit: Over-the-counter ranitidine products should not be used for more than 14 days without a doctor's guidance. Heartburn lasting more than 3 months may signal a more serious condition.
- Kidney impairment: Ranitidine is cleared mainly by the kidneys; people with kidney disease may need dose adjustments and closer monitoring.
Ranitidine interactions
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Ranitidine can affect how several other medications are absorbed or cleared from the body. Key interactions to know about:
- Warfarin (blood thinner): Ranitidine may alter clotting time — close monitoring is recommended if you take both.
- Procainamide (heart rhythm medication): High doses of ranitidine may raise procainamide levels; watch for signs of toxicity.
- Ketoconazole (antifungal): Ranitidine can reduce ketoconazole absorption by up to 95% — a significant interaction.
- Atazanavir and delavirdine (HIV medications): Ranitidine may reduce their effectiveness; chronic combined use with delavirdine is not recommended.
- Gefitinib (cancer treatment): Ranitidine can reduce gefitinib levels in the body — use with caution.
- Glipizide (diabetes medication): Ranitidine may increase glipizide exposure — monitor blood sugar when starting or stopping ranitidine.
- Midazolam and triazolam (sedatives): Oral ranitidine can increase blood levels of these drugs, raising the risk of excessive or prolonged sedation.
Interactions listed in the FDA-approved label
From the Ranitidine prescribing information (“Drug Interactions”): what the manufacturer studied or reported to the FDA.
- Procainamide: High doses of ranitidine have been shown to reduce the renal excretion of procainamide and N-acetylprocainamide, resulting in increased plasma levels of these drugs. Unlikely to be clinically relevant at usual doses; it may be prudent to monitor for procainamide toxicity with oral ranitidine at a dose exceeding 300 mg per day.
- Warfarin: There have been reports of altered prothrombin time among patients on concomitant warfarin and ranitidine therapy. Close monitoring of increased or decreased prothrombin time is recommended during concurrent treatment.
- Atazanavir: Atazanavir absorption may be impaired based on known interactions with other agents that increase gastric pH. Use with caution. See atazanavir label for specific recommendations.
- Delavirdine: Delavirdine absorption may be impaired based on known interactions with other agents that increase gastric pH. Chronic use of H2-receptor antagonists with delavirdine is not recommended.
- Gefitinib: Gefitinib exposure was reduced by 44% with the coadministration of ranitidine and sodium bicarbonate (dosed to maintain gastric pH above 5.0). Use with caution.
- Glipizide: In diabetic patients, glipizide exposure was increased by 34% following a single 150-mg dose of oral ranitidine. Use appropriate clinical monitoring when initiating or discontinuing ranitidine.
- Ketoconazole: Oral ketoconazole exposure was reduced by up to 95% when oral ranitidine was coadministered in a regimen to maintain a gastric pH of 6 or above; the degree of interaction with usual dose of ranitidine (150 mg twice daily) is unknown.
- Midazolam: Oral midazolam exposure in 5 healthy volunteers was increased by up to 65% with oral ranitidine 150 mg twice daily; in another study in 8 volunteers receiving intravenous midazolam, a 300 mg oral dose of ranitidine increased midazolam exposure by about 9%. Monitor patients for excessive or prolonged sedation when ranitidine is coadministered with oral midazolam.
- Triazolam: Triazolam exposure in healthy volunteers was increased by approximately 30% when administered with oral ranitidine at a dose of 150 mg twice daily. Monitor patients for excessive or prolonged sedation.
Read the label’s full interactions text
Drug Interactions Ranitidine has been reported to affect the bioavailability of other drugs through several different mechanisms such as competition for renal tubular secretion, alteration of gastric pH, and inhibition of cytochrome P450 enzymes. Procainamide: Ranitidine, a substrate of the renal organic cation transport system, may affect the clearance of other drugs eliminated by this route. High doses of ranitidine (e.g., such as those used in the treatment of Zollinger-Ellison syndrome) have been shown to reduce the renal excretion of procainamide and N-acetylprocainamide resulting in increased plasma levels of these drugs. Although this interaction is unlikely to be clinically relevant at usual ranitidine doses, it may be prudent to monitor for procainamide toxicity when administered with oral ranitidine at a dose exceeding 300 mg per day. Warfarin: There have been reports of altered prothrombin time among patients on concomitant warfarin and ranitidine therapy. Due to the narrow therapeutic index, close monitoring of increased or decreased prothrombin time is recommended during concurrent treatment with ranitidine. Ranitidine may alter the absorption of drugs in which gastric pH is an important determinant of bioavailability. This can result in either an increase in absorption (e.g., triazolam, midazolam, glipizide) or a decrease in absorption (e.g., ketoconazole, atazanavir, delavirdine, gefitinib). Appropriate clinical monitoring is recommended. Atazanavir: Atazanavir absorption may be impaired based on known interactions with other agents that increase gastric pH. Use with caution. See atazanavir label for specific recommendations. Delavirdine: Delavirdine absorption may be impaired based on known interactions with other agents that increase gastric pH. Chronic use of H 2 -receptor antagonists with delavirdine is not recommended.
Excerpted — the section continues on the label. Read the full Drug Interactions section on DailyMed →
Not a complete list. The label covers the interactions the manufacturer studied or reported, and our own interaction database does not cover every medicine either. Bring your full medication list, including vitamins and herbal products, to your pharmacist.
Before taking Ranitidine
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- Do not take ranitidine if you have a known allergy to it or to any of its ingredients.
- Tell your doctor if you have kidney disease — your dose may need to be adjusted based on how well your kidneys work.
- Older adults tend to clear ranitidine more slowly due to reduced kidney function; extra care and monitoring may be needed.
- If you are pregnant or breastfeeding, ask a health professional before using ranitidine.
- Children under 12 years old should not use OTC ranitidine products without a doctor's advice.
- Tell your prescriber about all other medications you take — ranitidine interacts with several prescription drugs including blood thinners, heart medications, antifungals, HIV drugs, diabetes medications, and sedatives.
- Ask a doctor before using OTC ranitidine if you have had heartburn for more than 3 months, frequent wheezing, unexplained weight loss, or persistent nausea or stomach pain.
Ranitidine overdose
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Taking too much ranitidine can cause side effects similar to those seen at normal doses, and in reported overdose cases there have also been abnormal walking (gait disturbances) and low blood pressure (hypotension). If an overdose is suspected, seek emergency medical help or contact Poison Control right away at 1-800-222-1222. Treatment focuses on removing any unabsorbed drug and providing supportive care as needed.
What Ranitidine does in the body
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Ranitidine significantly reduces the amount of acid the stomach produces — both at rest and in response to triggers like food. It is especially effective at suppressing basal acid output (the acid your stomach makes on its own, including at night), with near-complete suppression seen at standard doses. It is somewhat less potent against acid triggered by food or a substance called pentagastrin, but still provides meaningful reduction. Ranitidine does not affect pepsin secretion directly, does not meaningfully change levels of the gut hormone gastrin, and has no significant effect on a protein called intrinsic factor that helps absorb vitamin B12.
How your body processes Ranitidine
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After an oral dose, ranitidine is about 50% absorbed into the bloodstream, with peak blood levels typically reached within 2 to 3 hours. Food and most antacids do not significantly reduce this absorption. Ranitidine is only lightly bound to proteins in the blood (about 15%) and is distributed widely through the body. It is partially broken down by the liver, but most of the drug leaves the body unchanged through the urine within 24 hours. The elimination half-life — the time it takes the body to clear half the drug — is about 2.5 to 3 hours in healthy adults, but this extends to 3 to 4 hours in older adults and even longer in people with significant kidney impairment, meaning those groups may need dose adjustments.
How to store Ranitidine
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Store at 20° to 25°C (68° to 77°F) in a dry place. Protect from light. KEEP OUT OF THE REACH OF CHILDREN.
Written from the FDA-approved label with AI and reviewed by our pharmacy team. How we use AI →
Supplements & herbs that interact with Ranitidine
74 supplements and herbal products have documented interactions with Ranitidine in the licensed clinical database we use. Most are manageable — but your pharmacist should know about everything you take, including vitamins and herbals.
- Major · 2
- Moderate · 43
- Minor · 29
Educational information from a licensed clinical database (Natural Medicines) — see our data sources & update cadence. Not medical advice: an interaction being documented does not mean it will happen to you; do not start or stop medications or supplements without professional guidance.
Nutrient depletion considerations
Ranitidine has been associated with lower levels of 6 nutrients in the clinical literature. This does not mean a deficiency will occur — it means these may be worth discussing with your pharmacist or healthcare provider, especially with long-term use.
- Higher significance · 4
- Moderate · 1
- Unrated · 1
Educational information from a licensed clinical database (Natural Medicines) — not medical advice. Do not start or stop medications or supplements without professional guidance.
Ranitidine: pharmacist answers to common questions
Quick, plain-English answers to the questions patients ask most about Ranitidine — the kind of thing our pharmacy team would talk through with you at the counter.
What exactly is ranitidine used for?
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How should I take ranitidine — does it matter if I eat first?
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What side effects should I watch out for?
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Are there any medications I should not combine with ranitidine?
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Is it safe to take ranitidine if I have kidney problems?
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How long can I take OTC ranitidine for heartburn?
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Is Ranitidine available over the counter?
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When was Ranitidine first available?
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Who makes Ranitidine?
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Answers drafted from the FDA-approved label with AI and reviewed by our pharmacy team. How we use AI →
More about Ranitidine on HelloPharmacist
Ranitidine forms and strengths (how it comes)
Ranitidine is available in 3 forms. Different forms and brands can have different approved uses, doses, schedules, and directions. Follow the instructions for your exact product, and do not switch forms without guidance from your prescriber or pharmacist.
Tablet
How this form is used
- Ranitidine tablets are used for short-term treatment of active duodenal ulcers, active benign gastric ulcers, GERD, and erosive esophagitis.
- Ranitidine tablets are used as maintenance therapy to prevent recurrence of duodenal and gastric ulcers after healing.
- Acid Reducer tablets are used to relieve heartburn associated with acid indigestion and sour stomach.
- Acid Reducer tablets are used to prevent heartburn brought on by certain foods or beverages.
- Ranitidine tablets are taken by mouth with or without food, typically once or twice daily as directed by your prescriber.
- Acid Reducer tablets should be swallowed with a glass of water; to prevent heartburn, take one tablet 30 to 60 minutes before eating or drinking trigger foods.
- Acid Reducer tablets can be used up to twice daily — do not take more than 2 tablets in 24 hours.
- Children under 12 years should ask a doctor before using Acid Reducer tablets.
Capsule
How this form is used
- Ranitidine capsules are used for short-term treatment of active duodenal ulcers and active benign gastric ulcers.
- Ranitidine capsules are used as maintenance therapy to prevent ulcer recurrence after healing.
- Ranitidine Hydrochloride capsules are used to treat GERD and erosive esophagitis.
- Ranitidine Hydrochloride capsules are used for pathological hypersecretory conditions such as Zollinger-Ellison syndrome.
- Ranitidine and Ranitidine Hydrochloride capsules are taken by mouth and can be taken with or without food.
- Ranitidine Hydrochloride capsules are typically taken once or twice daily depending on the condition; follow your prescriber's directions.
- Antacids may be taken alongside Ranitidine Hydrochloride capsules as needed for pain relief.
- Follow your prescriber's guidance on how long to take Ranitidine or Ranitidine Hydrochloride capsules — duration varies by condition.
Oral solution
How this form is used
- Ranitidine oral solution is used for short-term treatment of active duodenal ulcers and active benign gastric ulcers.
- Ranitidine oral solution is used as maintenance therapy to prevent ulcer recurrence after healing.
- Ranitidine oral solution is used to treat GERD and erosive esophagitis.
- Ranitidine oral solution is used for pathological hypersecretory conditions such as Zollinger-Ellison syndrome.
- Ranitidine oral solution is taken by mouth, typically once or twice daily depending on the condition being treated.
- Ranitidine oral solution can be taken with or without food.
- Antacids may be used alongside Ranitidine oral solution as needed for pain relief.
- Follow your prescriber's instructions for how long to continue Ranitidine oral solution.
Ranitidine on the U.S. market: products, makers and brands
How Ranitidine appears in the FDA’s National Drug Code Directory — including its dosage forms, strengths, brand names, manufacturers, and FDA-listed product records. These are directory records, not sales or prescription volume.
8 companies list 17 Ranitidine product records with the FDA, mostly as tablet, capsule, oral solution; the earliest marketing or approval year on record is 1983. Brand names on the directory include Zantac, Zantac 75, Zantac EFFERdose and 4 more; the rest are generics.
FDA-listed product records by dose form (tablet variants merged) — FDA National Drug Code Directory. Record counts are not sales or prescription volume.
Also listed with the FDA, not a patient dose form: Powder (9) — bulk drug substance sold to compounders/manufacturers and multi-item kits. These aren’t counted in the dose-form total above.
Share of FDA-listed product records by manufacturer — FDA National Drug Code Directory. Record counts are not sales or prescription volume.
How widely Ranitidine is used (Medicaid data)
A general measure of how commonly Ranitidine is prescribed, based on Medicaid — one of the largest public drug programs. The figure below is prescriptions filled in Q1 2026, summed across every form and brand of the drug.
Think of this as a proxy for how widely Ranitidine is used, drawn from freely available public data. Medicaid is just one program — these numbers don’t include Medicare, other government coverage, or commercial and cash-pay prescriptions, so real-world use is higher than what’s shown here.
How commonly is Ranitidine prescribed? Of the 1,601 medications we measure, Ranitidine ranks #1,544 by Medicaid prescriptions — more than 4% of them.
Source: Medicaid State Drug Utilization Data (CMS), aggregated by generic ingredient — summed across every NDC (all brands, strengths, salt forms and dosage forms) of Ranitidine, and across all states and both fee-for-service and managed-care claims. A general popularity signal; it excludes Medicare, commercial insurance and cash prescriptions, so it is not total U.S. use. Based on the 1 of 198 listed Ranitidine NDCs with Medicaid activity.
Compare Ranitidine products
A representative set of FDA-listed product records for Ranitidine — across manufacturers, strengths, and dosage forms, grouped by form with each product’s manufacturer and how the FDA approved it. The same medicine may be made and packaged by different companies, so a single drug can have many directory entries. (It’s also why a refill can look different — a new shape, color, or box — even though it contains the same medication.)
| Strength | Route | Manufacturer / Labeler | Category ⓘ | Details |
|---|---|---|---|---|
| 💊Capsule | ||||
| 150 mg | Oral | Ajanta Pharma USA Inc. | ANDA | View NDC → |
| 300 mg | Oral | Ajanta Pharma USA Inc. | ANDA | View NDC → |
| 150 mg | Oral | Dr. Reddy's Laboratories Limited | ANDA | View NDC → |
| 300 mg | Oral | Dr. Reddy's Laboratories Limited | ANDA | View NDC → |
| 💊Oral solution | ||||
| 15 mg/mL | Oral | Pharmaceutical Associates, Inc. × 2 listings | ANDA | View NDC → |
| 💊Tablet | ||||
| 150 mg | Oral | Amneal Pharmaceuticals of New York LLC | ANDA | View NDC → |
| 300 mg | Oral | Amneal Pharmaceuticals of New York LLC | ANDA | View NDC → |
| 150 mg | Oral | Atland Pharmaceuticals, LLC | ANDA | View NDC → |
| 300 mg | Oral | Atland Pharmaceuticals, LLC | ANDA | View NDC → |
| 75 mg | Oral | Dr. Reddy's Laboratories Limited | ANDA | View NDC → |
| 150 mg | Oral | Dr. Reddy's Laboratories Limited | ANDA | View NDC → |
| 150 mg | Oral | Granules India Ltd × 2 listings | ANDA | View NDC → |
| 150 mg | Oral | Rising Pharma Holdings, Inc. | ANDA | View NDC → |
| 300 mg | Oral | Rising Pharma Holdings, Inc. | ANDA | View NDC → |
| 75 mg | Oral | WinCo Foods, LLC | ANDA | View NDC → |
Showing 17 of 17 products — FDA National Drug Code Directory. See every product, package size and price: browse all 17 Ranitidine NDCs →
Ranitidine side effects reported to the FDA (FAERS)
After a medicine reaches the market, patients, doctors and drugmakers can send the FDA reports of problems they think may be linked to it. Here’s what’s been reported for Ranitidine — a signal of what to watch for, not proof the drug caused it.
Source: openFDA, from the FDA Adverse Event Reporting System (FAERS). These are voluntary reports — they don’t prove the drug caused the effect, and counts reflect how often something was reported, not how often it actually happens. Reports also often name the very problem the medicine is taken for — a common reason to file one is that the drug didn’t help — so for a pain reliever you may see “pain” high on the list; that points to why the report was filed, not to the drug causing the symptom. This counts every report that lists Ranitidine in any role, so the total runs higher than the FDA’s official dashboard, which counts only cases where the drug is the suspect. For the authoritative figures, see the FDA FAERS Public Dashboard. Always talk to your pharmacist or doctor.
Ranitidine FDA approval history
How Ranitidine went from FDA review to the pharmacy shelf — the key milestones in its regulatory journey.
Source: Drugs@FDA.
Ranitidine recall history
A recall is when a specific batch of a medicine is pulled from the market — usually a manufacturing issue, not a problem with the drug itself. Class I is most serious, Class III least.
The FDA’s enforcement reports list no Ranitidine recalls since July 2021.
✅No Ranitidine recalls on record since July 2021Source: FDA enforcement (recall) reports, via openFDA; our copy was last updated Sep 24, 2026.
RxNorm Concept Web — From Ingredient to Every Form and Strength
This page starts with one ingredient concept (IN). The branches below show its dose-form concepts (SCDF), then the available clinical drug and strength concepts (SCD). Combination products remain separate concepts with their own pages.
RxCUI 9143 6 dose forms · 13 strengths
-
Dose form (SCDF) Effervescent Oral Tablet RxCUI 1536200In current FDA listingsClinical drug / strength (SCD) 25 MGRxCUI 60263975 MGRxCUI 1536915150 MGRxCUI 1536836300 MGRxCUI 1537068 -
Dose form (SCDF) Injectable Solution RxCUI 373751No current FDA listingClinical drug / strength (SCD) 25 MG/MLRxCUI 312772 -
Dose form (SCDF) Injection RxCUI 1859541No current FDA listingClinical drug / strength (SCD) 2 ML ranitidine 25 MG/MLRxCUI 1859553 -
Dose form (SCDF) Oral Capsule RxCUI 373750In current FDA listings -
Dose form (SCDF) Oral Solution RxCUI 379494In current FDA listingsClinical drug / strength (SCD) 15 MG/MLRxCUI 705610 -
Dose form (SCDF) Oral Tablet RxCUI 373752In current FDA listings
Look up RxCUI 9143 in the RxCUI Atlas →
RxNorm is the U.S. National Library of Medicine’s normalized drug vocabulary. Its concept hierarchy can include forms that are not currently marketed; the status on each branch compares that concept with current FDA listings. RxCUIs identify vocabulary concepts, not individual packages or manufacturers.
Ranitidine supply and shortage status
Whether Ranitidine is in short supply in the U.S. right now, plus any shortage history the FDA has on record. A shortage usually reflects a manufacturing or demand issue — not a safety problem with the drug.
Source: openFDA, from the FDA Drug Shortages database.
Ranitidine brand names
Ranitidine is sold under 7 brand names in the FDA directory — Zantac, Zantac 75, Zantac EFFERdose, Zantac Syrup and others. A brand and its generic contain the same active ingredient; the brand name belongs to one company's product.
Who makes Ranitidine: manufacturers and labelers
8 companies list Ranitidine products with the FDA. By number of product records, the largest are Dr. Reddy's Laboratories Limited, Ajanta Pharma USA Inc., Amneal Pharmaceuticals of New York LLC. Labelers include manufacturers and repackagers; the product in your bottle depends on which one your pharmacy stocks.
Ranitidine drug class (RxNorm)
Ranitidine belongs to the Histamine-2 Receptor Antagonist class.
Classified by RxNorm RxClass — the U.S. National Library of Medicine's standardized drug-classification service (Established Pharmacologic Class from the FDA, the ATC drug family from the WHO, and mechanism of action). Reference only, not medical advice.
Sources for this Ranitidine page
Core label, product, RxNorm, safety, and utilization data on this page come from the sources identified below. AI-written, editorial, and licensed sections are labeled separately.
How this page is built
HelloPharmacist combines public FDA and NLM records and does not author the underlying clinical facts. The plain-language sections are written with AI from the FDA-approved label text and reviewed by our pharmacy team before publication. Bryant Ranch Prepack is the representative DailyMed label linked for verification and dates. This is general education, not medical advice: always talk to your doctor or pharmacist about your own medicines. How we build and review drug pages →