FDA-filed SPL labeling · retrieved through openFDA

Undecylenic

Undecylenic acid is an antifungal ingredient used across multiple topical products to treat athlete's foot, jock itch, and ringworm.

Brand names Blis-To-Sol PowderElon Dual DefenseTineacide AntifungalHongo Killer TreatmentFungiCure Maximum Strength +11 more
OTC Forms 5 Routes Topical · Cutaneous · Cutaneous, Extracorporeal, Percutaneous
Dr. Brian Staiger, PharmD, BCPS
Reviewed by Last reviewed Aug 23, 2026
🧬 Where this information comes from Click to expand

The clinical label records used on this page are FDA-filed Structured Product Labeling (SPL) retrieved through openFDA. We identified 99 clinical label sets within the page’s selected clinical scope after exact ingredient or ingredient-combination matching and applicable route/form matching. Forms, routes, brands, labelers, strengths, and NDC product-record counts are built separately from matching FDA National Drug Code Directory records. The linked DailyMed document is a representative official source for verification, not the page’s only clinical source. View the linked label on DailyMed →

At a glance
Linked label effectiveJul 28, 2026
Clinical labels in scope ⓘ99
AvailabilityOTC
Earliest approval/marketing year ⓘ2010
FDA-listed product records ⓘ168
Boxed warningNone found in compared labels
How we combine label and product data →
✓No current FDA shortage listed · checked Sep 27, 2026 🚨Recall on record · 3
⭐ Undecylenic at a glance The quick version — the full detail is in the Patient Information Guide below.
💊
HelloPharmacist Editorial Team Bottom Line
Undecylenic acid is a well-established antifungal available in many over-the-counter topical forms to treat athlete's foot, jock itch, and ringworm. Apply it twice daily to clean, dry skin and stick with it for the full recommended course — 2 weeks for jock itch, 4 weeks for athlete's foot or ringworm. If you're not seeing improvement by then, check in with a doctor.
How we write & review this content — our editorial policy →

📖 Undecylenic: Patient Information Guide

A plain-language walkthrough of Undecylenic — what it treats, how it works, how it’s taken, side effects, warnings and interactions. Tap any section to expand it.

🎯What it's used for▾

Undecylenic acid is an antifungal ingredient found in a wide range of over-the-counter topical products for common fungal skin infections.

  • Treats athlete's foot (tinea pedis) — including itchy, scaly skin between the toes
  • Treats jock itch (tinea cruris) — including itching, scaling, cracking, burning, redness, soreness, and discomfort
  • Treats ringworm (tinea corporis)
  • Helps prevent athlete's foot from coming back with daily use (supported by several products including QualiLife persimmon foot and shoe spray and Avenaster Fungal Nail Care Duo Set)
  • Fungal Nail Patches: also aimed at improving nail appearance and reducing discoloration and thickness of damaged nails
  • QualiLife persimmon foot and shoe spray: also used for odor control and deodorizing shoes and feet
  • Aiilo NAIL FUNGUS TREATMENT solution: addresses nail discoloration, thickening, splitting, crumbling, and brittleness
  • Most products are not effective on the scalp or nails — always check your specific product's label
💊How it's taken▾

Undecylenic acid is applied directly to the skin, typically twice a day — morning and night. Always start by cleaning and thoroughly drying the affected area before applying. The length of treatment depends on the infection:

  • Athlete's foot and ringworm: use daily for 4 weeks
  • Jock itch: use daily for 2 weeks
  • For athlete's foot, pay extra attention to the spaces between toes; wear well-fitting, ventilated shoes and change shoes and socks at least once daily
  • Aiilo NAIL FUNGUS TREATMENT: for initial use, soak the nail in warm water, gently file to thin it and remove debris, then apply 2–3 drops; continue filing every 2–3 days for best results

Follow your specific product's directions closely. If the condition is not improving by the end of the recommended treatment window, contact your doctor before continuing.

🤒Side effects — in detail▾

Undecylenic acid is generally well tolerated on the skin. The main side effect noted on product labels is:

  • Skin irritation at the application site

If irritation develops or your symptoms are not improving within the expected timeframe (4 weeks for athlete's foot or ringworm; 2 weeks for jock itch), stop using the product and talk to a doctor.

⚠️Warnings & precautions▾
  • External use only — never swallow; if accidentally ingested, call a Poison Control Center immediately
  • Keep away from eyes — avoid contact during application
  • Not effective on the scalp or nails for most products — do not apply to these areas unless your specific product is formulated for nail use
  • Do not use on children under 2 without a doctor's direction
  • Children using these products should be supervised by an adult
  • Persons under 18 or those with highly sensitive or allergic skin should use only as directed by a physician (per select product labels)
  • Stop use and see a doctor if irritation occurs or there is no improvement within the recommended treatment window
🔀What it interacts with▾

The supplied product labels do not describe specific drug, food, or supplement interactions for undecylenic acid topical products.

This is not a complete list of interactions. Always talk with your doctor or pharmacist before starting, stopping, or changing any medication.

📋Before taking it▾
  • Do not use on children under 2 years of age unless a doctor recommends it
  • Children should use this product under adult supervision
  • People with sensitive or allergic skin, or those under 18, should use only as directed by a physician (per select labels)
  • For external use only — do not apply to eyes, scalp, or nails unless your specific product is intended for that area
🚑If you take too much▾

These are topical products meant for skin use only. If accidentally swallowed, seek professional assistance or contact a Poison Control Center immediately.

📦How to store it▾

Store between 20° to 25°C (68° to 77°F)

📄 Written from Undecylenic’s FDA-approved label information, summarized in plain language with AI, and reviewed by our pharmacy team before publication. Every point is grounded in that labeling — nothing is invented. How we use AI →

🩺 Pharmacist Counseling Corner

Quick, plain-English answers to the questions patients ask most about Undecylenic — the kind of thing our pharmacy team would talk through with you at the counter.

What exactly does undecylenic acid treat? ▾
It treats three common fungal skin infections: athlete's foot (the itchy, scaly condition that affects the feet and toes), jock itch (a fungal rash in the groin area), and ringworm (a ring-shaped fungal rash on the skin). Some products also target discolored, thickened, or brittle nails. Always check your specific product's label to confirm which conditions it's approved for.
How long does it take to work? ▾
For athlete's foot and ringworm, most products are used daily for 4 full weeks. For jock itch, 2 weeks of daily use is typically recommended. Some nail products note that visible improvement may appear in as little as 7 days, but you should continue regular use to help prevent the fungus from coming back. If you're not seeing any improvement by the end of the recommended window, it's a good idea to check in with your doctor.
Can I use this on my nails? ▾
That depends on the product. Most undecylenic acid creams, sprays, and general topical solutions are not effective on nails and should not be used there. However, some products — like Aiilo NAIL FUNGUS TREATMENT and Fungal Nail Patches — are specifically designed for nail concerns such as discoloration, thickening, and brittleness. Check your product's label carefully before applying to nails.
Is it safe for kids? ▾
Most products should not be used on children under 2 years of age unless a doctor says it's okay. For older children, an adult should supervise use. A few product labels also note that people under 18 or those with very sensitive skin should use the product only under a doctor's guidance. When in doubt, ask your child's pediatrician.
What should I do if my skin gets irritated? ▾
Stop using the product right away and ask a doctor. A little redness when you first start is not unusual, but true irritation — worsening redness, burning, or swelling — is a reason to pause and get professional advice. Don't push through significant irritation hoping it will settle down on its own.
Any special tips for getting the best results with athlete's foot? ▾
Yes — the technique matters as much as the medicine. Make sure you wash and thoroughly dry your feet before each application, and pay special attention to the spaces between your toes where fungus loves to hide. Wear well-fitting, ventilated shoes and change your shoes and socks at least once a day. Once the infection clears, continuing to apply the product once or twice daily can help prevent it from coming back.
Is Undecylenic available over the counter? ▾
Yes — Undecylenic is available over the counter (without a prescription) in at least some forms, according to its FDA labeling. Follow the package directions and ask your pharmacist if you're unsure which product is right for you.
When was Undecylenic first available? ▾
Undecylenic has been available in the United States since at least 2010, based on FDA approval history (Drugs@FDA) and product marketing records.
Who makes Undecylenic? ▾
Undecylenic is supplied by 63 manufacturers listed in the FDA NDC Directory, including Jiangxi Yudexi Pharmaceutical Co., LTD, Blaine Labs Inc., Wenzhou Yuyuan Pharmaceutical Co., Ltd..

💬 Answers drafted from Undecylenic’s FDA-approved label information, summarized in plain language with AI, and reviewed by our pharmacy team before publication. Grounded in that labeling — nothing is made up. How we use AI →

🧰 Keep exploring

🌿Drug & Supplement CheckerUndecylenic vs. vitamins & herbs 💬Ask a PharmacistFree answer, usually < 24h 🔎NDC & pricing lookupFind Undecylenic NDCs & costs 🅰️Browse Drugs A–ZLook up any medication

💊 How Undecylenic comes

Undecylenic is available in 5 forms. Different forms and brands can have different approved uses, doses, schedules, and directions. Follow the instructions for your exact product, and do not switch forms without guidance from your prescriber or pharmacist.

Topical solution

On the skin
Brands BeamBalm ANTIFUNGAL CARE ESSENTIAL Oil EmoniNail Antifungal Hongo Killer
How this form is used
What it may be used for
  • Aiilo NAIL FUNGUS TREATMENT: addresses nail discoloration, thickening, splitting, crumbling, and brittleness
  • Assielf Antifungal Pen: treats athlete's foot and ringworm
  • Avenaster Fungal Nail Care Duo Set (night): helps prevent fungal infections; treats most athlete's foot and ringworm; relieves itching, scaling, cracking, burning, redness, soreness, and irritation
Important instructions
  • Aiilo NAIL FUNGUS TREATMENT: apply twice daily (morning and night); for first use, soak nail in warm water, gently file nail to thin it and remove debris — repeat filing every 2–3 days; hold bottle at an angle and apply 2–3 drops evenly to affected area
  • Assielf Antifungal Pen: for external use only; avoid contact with eyes; do not use on children under 2 unless directed by a doctor
  • Avenaster Fungal Nail Care Duo Set (night): apply to clean, dry skin as directed; follow package directions
Available strengths 22 strengths
0.25 mg/30 mL 3.75 mg/15 mL 25 mg/30 g 25 mg/30 mL 25 mg/100 mL 100 mg/mL
Show 16 more strengths Show fewer strengths
200 mg/mL 0.23125 g/39.01 mL 0.25 g/L 0.25 g/mL 250 mg/100 mL 250 mg/g 250 mg/mL 300 mg/mL 1 g/4 mL 1.1 g/10 mL 7.5 g/30 mL 10 g/100 mL 15 g/100 mL 24.8 g/100 mL 25 g/100 g 25 g/100 mL
122 FDA-listed product records ⓘ

Topical cream, ointment or gel

On the skin
Brands Funginix Anti-fungal Treatment Terpenicol Vite20
How this form is used
What it may be used for
  • Funginix Anti-fungal Treatment: treats ringworm and athlete's foot; relieves itching, scaling, cracking, burning, redness, soreness, and irritation
  • Jelvoxa Antifungal: treats athlete's foot and ringworm (4 weeks) and jock itch (2 weeks); not effective on the scalp or nails
  • Tripenicol C: treats athlete's foot and ringworm (4 weeks) and jock itch (2 weeks); not effective on the scalp or nails
  • Vite20: treats athlete's foot (tinea pedis), jock itch (tinea cruris), and ringworm (tinea corporis); relieves itching, cracking, and burning
Important instructions
  • Funginix Anti-fungal Treatment: clean area with soap and warm water, dry thoroughly, apply a thin layer twice daily (morning and night); apply to cuticles, around nail edges, and under nail tips where reachable — this product does not penetrate hard nail surfaces
  • Jelvoxa Antifungal: wash and dry area thoroughly; apply a thin layer twice daily; for athlete's foot, pay attention to spaces between toes
  • Tripenicol C: wash affected area with soap and water, dry thoroughly; apply a thin layer twice daily; wash hands after each use
  • Vite20: wash affected area with soap and water, dry thoroughly; apply sparingly twice daily; for athlete's foot, pay attention to spaces between toes
Available strengths 14 strengths
2 mg/20 mL 4.8 mg/36.97 mL 14.77 mg/59.148 mL 85 mg/mL 0.13 g/mL 200 mg/mL
Show 8 more strengths Show fewer strengths
250 mg/mL 4.55 g/37.5 mL 10 g/100 g 10 g/100 mL 13 g/100 g 15 g/100 mL 25 g/100 mL 0.2508 kg/kg
25 FDA-listed product records ⓘ

Topical spray

On the skin
Brands Hongo Killer
How this form is used
What it may be used for
  • Mata Hongos: treats athlete's foot; not effective on the scalp or nails
  • QualiLife persimmon foot and shoe: treats most athlete's foot; relieves itchy, scaly skin between toes; controls odor and deodorizes shoes and feet; helps prevent most athlete's foot with daily use
Important instructions
  • Mata Hongos: wash and dry area thoroughly; spray a thin layer twice daily (morning and night); pay attention to spaces between toes
  • QualiLife persimmon foot and shoe (feet): wash affected area and dry thoroughly; spray a thin layer twice daily; use daily for 4 weeks for athlete's foot
  • QualiLife persimmon foot and shoe (shoes): allow shoes to sit 15+ minutes after wearing; shake bottle lightly, spray 1–2 times in each shoe; let shoes dry 10+ minutes before wearing
Available strengths 7 strengths
2 mg/10 mL 20 mg/100 mL 25 mg/60 mL 25 mg/100 mL 100 mg/mL 10 g/100 mL
Show 1 more strength Show fewer strengths
25 g/100 mL
17 FDA-listed product records ⓘ

Skin patch

Extracorporeal · On the skin
Brands Fungal Nail Patches
How this form is used
What it may be used for
  • Fungal Nail Patches: treats most athlete's foot (tinea pedis), jock itch (tinea cruris), and ringworm (tinea corporis)
  • Fungal Nail Patches: relieves itching, burning, cracking, and discomfort from these infections
  • Fungal Nail Patches: aimed at improving nail appearance and reducing discoloration and thickness of damaged nails
Important instructions
  • Fungal Nail Patches: apply as directed to the affected area
  • Fungal Nail Patches: follow all package directions; supervise children during use
Available strengths 1 strength
25 g/100 g
3 FDA-listed product records ⓘ

Oral solution

By mouth
Available strengths 1 strength
250 g/L
1 FDA-listed product record ⓘ

📊 Undecylenic across the U.S. market

How Undecylenic appears in the FDA’s National Drug Code Directory — including its dosage forms, strengths, brand names, manufacturers, and FDA-listed product records. These are directory records, not sales or prescription volume.

5
Dose forms ⓘ
63
Manufacturers
40
Brand names
168
FDA-listed product records ⓘ
2010
First marketed ⓘ

FDA-listed product records by dose form (tablet variants merged) — FDA National Drug Code Directory. Record counts are not sales or prescription volume.

Jiangxi Yudexi Pharmaceutical Co., LTD17%
Blaine Labs Inc.7%
Wenzhou Yuyuan Pharmaceutical Co., Ltd.6%
Menper Distributors, Inc.5%
Efficient Laboratories Inc4%
Pure Source, LLC3%
Other makers58%

Share of FDA-listed product records by manufacturer — FDA National Drug Code Directory. Record counts are not sales or prescription volume.

📈 How widely Undecylenic is used

A general measure of how commonly Undecylenic is prescribed, based on Medicaid — one of the largest public drug programs. The figure below is prescriptions filled in Q1–Q4 2025, summed across every form and brand of the drug.

Think of this as a proxy for how widely Undecylenic is used, drawn from freely available public data. Medicaid is just one program — these numbers don’t include Medicare, other government coverage, or commercial and cash-pay prescriptions, so real-world use is higher than what’s shown here.

45
Medicaid prescriptions filled (Q1–Q4 2025)
$22,427 gross Medicaid reimbursement (before mandatory rebates — net cost is lower)

How commonly is Undecylenic prescribed? Of the 1,597 medications we measure, Undecylenic ranks #1,544 by Medicaid prescriptions — more than 3% of them.

Where Undecylenic ranks among the drugs we measure · Q1–Q4 2025 · neighbors ±5
Total prescriptions — #1,544 of 1,597
#1,539 Miglitol 52 Rx #1,540 Edaravone Injection 52 Rx #1,541 Mycophenolate Injectio... 52 Rx #1,542 Amisulpride Injection 49 Rx #1,543 Midostaurin 47 Rx #1,544 Entrectinib 45 Rx #1,545 Undecylenic 45 Rx #1,546 Fludarabine Injection 44 Rx #1,547 Brolucizumab-dbll Inje... 43 Rx #1,548 Cobicistat 42 Rx #1,549 Luliconazole Topical 41 Rx

Utilization by Undecylenic product

Pick a product to see its own Medicaid numbers. Each chip is one clinical product — a specific strength & dosage form as defined by RxNorm — with brand-name and generic versions combined.

undecylenic acid 130 MG/ML Topical Cream

45 Medicaid prescriptions (Q1–Q4 2025) 100% of Undecylenic prescriptions shown $22,427 gross reimbursement (before rebates) ≈ $498 per prescription (gross)

Summed across the 1 of 1 listed NDC products with Medicaid activity — every brand and generic of this exact strength & form. RxNorm 1250978

Shares are of the Medicaid prescriptions shown here. Product grouping follows RxNorm (the National Library of Medicine’s drug terminology), so “one product” means one strength & dosage form regardless of manufacturer. Dollar figures are gross Medicaid reimbursement before mandatory rebates — rebates (often large, especially for brand-name drugs) are confidential, so actual net cost to Medicaid is lower than shown.

Source: Medicaid State Drug Utilization Data (CMS), aggregated by generic ingredient — summed across every NDC (all brands, strengths, salt forms and dosage forms) of Undecylenic, and across all states and both fee-for-service and managed-care claims. A general popularity signal; it excludes Medicare, commercial insurance and cash prescriptions, so it is not total U.S. use. Based on the 1 of 1 listed Undecylenic NDCs with Medicaid activity.

🔍 Compare Undecylenic products

A representative set of FDA-listed product records for Undecylenic — across manufacturers, strengths, and dosage forms, grouped by form with each product’s manufacturer and how the FDA approved it. The same medicine may be made and packaged by different companies, so a single drug can have many directory entries. (It’s also why a refill can look different — a new shape, color, or box — even though it contains the same medication.)

Showing 168 of 168 products — FDA National Drug Code Directory. See every product, package size and price: browse all 168 Undecylenic NDCs →

RxNorm Concept Web — From Ingredient to Every Form and Strength

This page starts with one ingredient concept (IN). The branches below show its dose-form concepts (SCDF), then the available clinical drug and strength concepts (SCD). Combination products remain separate concepts with their own pages.

Ingredient (IN) Undecylenic RxCUI 314881 7 dose forms · 24 strengths
  1. Dose form (SCDF) Medicated Patch RxCUI 2694116 In current FDA listings
    Clinical drug / strength (SCD) undecylenic acid 0.08 MG/MG RxCUI 2694118 undecylenic acid 0.25 MG/MG RxCUI 2730150
  3. Dose form (SCDF) Topical Gel RxCUI 1362032 In current FDA listings
    Clinical drug / strength (SCD) undecylenic acid 0.25 MG/MG RxCUI 1362039
  4. Dose form (SCDF) Topical Ointment RxCUI 647576 In current FDA listings
    Clinical drug / strength (SCD) undecylenic acid 0.1 MG/MG RxCUI 1250560 zinc undecylenate 0.1 MG/MG RxCUI 2712154
  5. Dose form (SCDF) Topical Powder RxCUI 619228 No current FDA listing
    Clinical drug / strength (SCD) calcium undecylenate 0.1 MG/MG RxCUI 562463 undecylenic acid 0.1 MG/MG RxCUI 1251000 zinc undecylenate 0.12 MG/MG RxCUI 562608

Look up RxCUI 314881 in the RxCUI Atlas →

RxNorm is the U.S. National Library of Medicine’s normalized drug vocabulary. Its concept hierarchy can include forms that are not currently marketed; the status on each branch compares that concept with current FDA listings. RxCUIs identify vocabulary concepts, not individual packages or manufacturers.

🏷️ Sold under these brand names

Blis-To-Sol Powder Elon Dual Defense Tineacide Antifungal Hongo Killer Treatment FungiCure Maximum Strength Hongo Killer Fiore Diaderm Tripenicol Terpenicol Fungi-Nail Funginix Anti-fungal Treatment EmoniNail Antifungal Vite20 Fungal Nail Patches BeamBalm ANTIFUNGAL CARE ESSENTIAL Oil

🏭 Manufacturers & labelers

Jiangxi Yudexi Pharmaceutical Co., LTD 25 Blaine Labs Inc. 10 Wenzhou Yuyuan Pharmaceutical Co., Ltd. 8 Menper Distributors, Inc. 7 Efficient Laboratories Inc 6 Pure Source, LLC 5 Guangzhou Hechuang Commercial Service Co.,Ltd. 5 Sansar, LLC 5 Guangdong Quadrant Ecological Technology Co., Ltd. 4 Kramer Laboratories 4 Trifluent Pharma LLC 4 The Sisquoc Healthcare Corporation 4 Topco Associates Llc 3 Little Giant Holdings LLC 3 Guangzhou Huixue Biotechnology Co., Ltd. 3 Pharmacy Value Alliance, Llc 3 Triple Point Group, LLC 3 Yunqi Cosmetics (Shenzhen) Co., Ltd 3 CVS Pharmacy 3 Human Science, Llc 2 Adwill Labs Inc 2 Chemco Corporation 2 Compania Internacional de Comercio, S.A.P.I de C.V. 2 Shenzhen Shandian Jingling Technology Co., Ltd. 2

…and 16 more on the FDA NDC directory.

RxNorm drug class

Undecylenic belongs to the Other antifungals for topical use class.

Drug family (ATC) Other antifungals for topical use

Classified by RxNorm RxClass — the U.S. National Library of Medicine's standardized drug-classification service (Established Pharmacologic Class from the FDA, the ATC drug family from the WHO, and mechanism of action). Reference only, not medical advice.

🔬 Where this comes from

Core label, product, RxNorm, safety, and utilization data on this page come from the sources identified below. AI-written, editorial, and licensed sections are labeled separately.

📄
FDA-filed drug labels (SPL) Uses, dosing, warnings & side effects from SPL records retrieved through openFDA; the linked representative set can be verified on DailyMed. ✓ Linked label effective Jul 28, 2026
🏭
Forms, brands & labelersAggregated from ingredient-matched FDA National Drug Code Directory product records for Undecylenic.
📈
Real-world reportsThe FDA Adverse Event Reporting System (FAERS), served through openFDA.
🚨
Recalls & shortagesopenFDA drug-enforcement reports and the FDA drug-shortage database.
🧾 Clinical label set — FDA-filed SPL labels retained for Undecylenic after exact ingredient or ingredient-combination matching and applicable route/form matching
Clinical labels in scope
99
NDC products indexed
168
Distinct labelers/manufacturers represented
63
Linked representative label ⓘ
Guangzhou Bixiaoyu Trading Co., Ltd.
Linked label effective
Jul 28, 2026
Composite sections available
7
Linked SPL Set ID
57a9ccff-270b-9769-e063-6394a90a5e0c
Linked SPL Document ID
57a9ccff-270c-9769-e063-6394a90a5e0c
Open the linked representative label on DailyMed ↗

How we combine label and product data

HelloPharmacist combines public FDA and NLM records; we don’t author the underlying clinical facts. We identified 99 FDA-filed SPL label sets within the page’s selected clinical scope after exact ingredient or ingredient-combination matching and applicable route/form matching. The representative label is the starting point for the displayed reference monograph; the 12 largest stored in-scope SPL records, which may include that representative, are compared section by section, and the longest available version of each section is retained. Forms, routes, brands, labelers, product-listed strengths, and product-record counts are aggregated separately from ingredient-matched FDA NDC Directory records; package records listed above are associated with the linked SPL; and the normalized concept hierarchy comes from NLM RxNorm.

For canonical ingredient pages, bounded product-attributed indication and administration excerpts may be added to the AI evidence, and the generator is instructed to preserve available product, brand, route, and form qualifiers instead of treating one label as universal. Where a section is identified as AI-written, its plain-language text is generated from bounded label evidence. New draft drug pages remain in the admin review queue before first publication. Guangzhou Bixiaoyu Trading Co., Ltd. is the representative DailyMed label linked for verification and dates; it is not the sole source used for the page.

This is general education, not medical advice — always consult your doctor or pharmacist about your medications and any medical condition. For the exact wording of the linked representative label, view that label on DailyMed; some displayed composite sections may come from other in-scope SPL labels. Learn how we use AI and our data sources & update cadence.