Vemurafenib

Generic name: Pronounced as (vem'' ue raf' e nib)
Brand names
  • Zelboraf®
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Medical Content Reviewed By HelloPharmacist Staff

Last Revised - 01/15/2018

Vemurafenib is used to treat certain types of melanoma (a type of skin cancer) that cannot be treated with surgery or that has spread to other parts of the body. It is also used to treat a certain type of Erdheim-Chester disease (ECD; a disease that causes an overproduction of a type of white blood cells). Vemurafenib is in a class of medications called kinase inhibitors. It works by blocking the action of an abnormal protein that signals cancer cells to multiply. This helps slow or stop the spread of cancer cells.

Vemurafenib comes as a tablet to take by mouth. It is usually taken with or without food twice a day, in the morning and evening, about 12 hours apart. Take vemurafenib at around the same times every day. Follow the directions on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand. Take vemurafenib exactly as directed. Do not take more or less of it or take it more often than prescribed by your doctor. Do not stop taking vemurafenib without talking to your doctor.

Swallow the tablets whole with a glass of water; do not chew or crush them.

If you vomit after you take vemurafenib, do not immediately take another dose. Continue your regular dosing schedule.

Your doctor may need to temporarily or permanently stop your treatment or decrease your dose of vemurafenib during your treatment.This depends on how well the medication works for you and the side effects you experience. Be sure to tell your doctor how you are feeling during your treatment with vemurafenib.

Your doctor or pharmacist will give you the manufacturer's patient information sheet (Medication Guide) when you begin treatment with vemurafenib and each time you refill your prescription. Read the information carefully and ask your doctor or pharmacist if you have any questions. You can also visit the Food and Drug Administration (FDA) website (http://www.fda.gov/Drugs/DrugSafety/ucm085729.htm) or the manufacturer's website to obtain the Medication Guide.

This medication may be prescribed for other uses; ask your doctor or pharmacist for more information.

Before taking vemurafenib,

  • tell your doctor and pharmacist if you are allergic to vemurafenib, any other medications, or any of the ingredients in vemurafenib tablets. Ask your pharmacist or check the Medication Guide for a list of the ingredients.

  • tell your doctor and pharmacist what other prescription and nonprescription medications, vitamins, nutritional supplements, and herbal products you are taking or plan to take. Be sure to mention any of the following: certain antifungals such as itraconazole (Onmel, Sporanox), ketoconazole (Nizoral), and voriconazole (Vfend); clarithromycin (Biaxin, in PrevPac); certain medications for human immunodeficiency virus (HIV) or acquired immunodeficiency syndrome (AIDS) such as indinavir (Crixivan), nelfinavir (Viracept), ritonavir (Norvir, in Kaletra), and saquinavir (Invirase); certain medications for seizures such as carbamazepine (Carbatrol, Epitol, Tegretol, others), phenobarbital, and phenytoin (Dilantin, Phenytek); nefazodone; rifampin (Rifadin, Rimactane, in Rifamate, in Rifater); tizanidine; and warfarin (Coumadin, Jantoven). Your doctor may need to change the doses of your medications or monitor you carefully for side effects. Many other medications may also interact with vemurafenib, so be sure to tell your doctor about all the medications you are taking, even those that do not appear on this list.

  • tell your doctor if you have or have ever had any type of skin cancer; a prolonged QT interval (a rare heart problem that may cause irregular heartbeat, fainting, or sudden death); heart failure; a low level of calcium, magnesium, or potassium in your blood; heart, kidney, or liver disease. Also, tell your doctor if you have had or are planning to receive radiation therapy.

  • tell your doctor if you are pregnant or plan to become pregnant. You should not become pregnant while you are taking vemurafenib. You should use birth control to prevent pregnancy during your treatment with vemurafenib and for 2 weeks after your final dose. Talk to your doctor about birth control methods that will work for you. If you become pregnant while taking vemurafenib, call your doctor. Vemurafenib may harm the fetus.

  • tell your doctor if you are breastfeeding. You should not breastfeed while taking vemurafenib and for 2 weeks after your final dose.

  • if you are having surgery, including dental surgery, tell the doctor or dentist that you are taking vemurafenib.

  • plan to avoid unnecessary or prolonged exposure to sunlight and to wear protective clothing, sunglasses, lip balm and sunscreen (SPF 30 or higher). Vemurafenib may make your skin sensitive to sunlight.

Unless your doctor tells you otherwise, continue your normal diet.

Take the missed dose as soon as you remember it. However, if it is within 4 hours of your next scheduled dose, skip the missed dose and continue your regular dosing schedule. Do not take a double dose to make up for a missed one.

  • Vemurafenib may cause side effects. Tell your doctor if any of these symptoms are severe or do not go away:

    • tiredness

    • joint, muscle, arm, leg, or back pain

    • redness or swelling in hands, feet, ankles, or lower legs

    • change in sense of taste

    • headache

    • hair loss

    • dry or itchy skin

    • diarrhea

    • constipation

    • cough

  • Some side effects can be serious. If you experience any of these symptoms, call your doctor immediately:

    • changes in skin appearance

    • new wart

    • skin sore or red bump that bleeds or does not heal

    • change in size or color of a mole

    • extreme tiredness

    • unusual bruising or bleeding

    • nausea

    • vomiting

    • loss of appetite

    • pain in the upper right part of the stomach

    • yellowing of the skin or eyes

    • eye sensitivity to light

    • eye redness or pain

    • vision changes

    • unusual thickening of palms of hands

    • tightening of the fingers inwards towards the palm

    • unusual thickening of soles of feet, that may be painful

  • If you experience any of the following symptoms of an allergic reaction or severe skin reaction, stop taking vemurafenib and call your doctor immediately or get emergency medical treatment:

    • difficulty breathing or swallowing

    • rapid, irregular, or pounding heartbeats

    • fainting

    • rash or redness all over the body

    • hives

    • peeling or blistering skin

    • fever

  • Vemurafenib may increase the risk that you will develop other cancers. Talk to your doctor about this risk.

  • Vemurafenib may cause other side effects. Call your doctor if you have any unusual problems while taking this medication.

  • If you experience a serious side effect, you or your doctor may send a report to the Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting program online (http://www.fda.gov/Safety/MedWatch) or by phone (1-800-332-1088).

Keep this medication in the container it came in, tightly closed, and out of reach of children. Store it at room temperature and away from excess heat and moisture (not in the bathroom).

It is important to keep all medication out of sight and reach of children as many containers (such as weekly pill minders and those for eye drops, creams, patches, and inhalers) are not child-resistant and young children can open them easily. To protect young children from poisoning, always lock safety caps and immediately place the medication in a safe location – one that is up and away and out of their sight and reach. http://www.upandaway.org

Unneeded medications should be disposed of in special ways to ensure that pets, children, and other people cannot consume them. However, you should not flush this medication down the toilet. Instead, the best way to dispose of your medication is through a medicine take-back program. Talk to your pharmacist or contact your local garbage/recycling department to learn about take-back programs in your community. See the FDA's Safe Disposal of Medicines website (http://goo.gl/c4Rm4p) for more information if you do not have access to a take-back program.

In case of overdose, call the poison control helpline at 1-800-222-1222. Information is also available online at https://www.poisonhelp.org/help. If the victim has collapsed, had a seizure, has trouble breathing, or can't be awakened, immediately call emergency services at 911.

Keep all appointments with your doctor and the laboratory. Your doctor will order certain lab tests to check your body's response to vemurafenib. Your doctor will check your skin before starting treatment, every 2 months during your treatment, and for up to 6 months after treatment.

Do not let anyone else take your medication. Ask your pharmacist any questions you have about refilling your prescription.

It is important for you to keep a written list of all of the prescription and nonprescription (over-the-counter) medicines you are taking, as well as any products such as vitamins, minerals, or other dietary supplements. You should bring this list with you each time you visit a doctor or if you are admitted to a hospital. It is also important information to carry with you in case of emergencies.

Drug Interaction
Moxifloxacin Moxifloxacin The risk or severity of QTc prolongation can be increased when Moxifloxacin is combined with Vemurafenib.
Repaglinide Repaglinide The metabolism of Repaglinide can be decreased when combined with Vemurafenib.
Montelukast Montelukast The metabolism of Montelukast can be decreased when combined with Vemurafenib.
Insulin Glargine (rDNA origin) Injection Insulin Glargine (rDNA origin) Injection The therapeutic efficacy of Insulin glargine can be increased when used in combination with Vemurafenib.
Leflunomide Leflunomide The serum concentration of Leflunomide can be increased when it is combined with Vemurafenib.
Delavirdine Delavirdine The metabolism of Delavirdine can be decreased when combined with Vemurafenib.
Nevirapine Nevirapine The metabolism of Nevirapine can be decreased when combined with Vemurafenib.
Atorvastatin Atorvastatin The metabolism of Atorvastatin can be decreased when combined with Vemurafenib.
Dolasetron Dolasetron The risk or severity of QTc prolongation can be increased when Dolasetron is combined with Vemurafenib.
Aminophylline Aminophylline The serum concentration of Aminophylline can be increased when it is combined with Vemurafenib.
Anagrelide Anagrelide The serum concentration of Anagrelide can be increased when it is combined with Vemurafenib.
Candesartan Candesartan The metabolism of Candesartan can be decreased when combined with Vemurafenib.
Cilostazol Cilostazol The serum concentration of Cilostazol can be increased when it is combined with Vemurafenib.
Clopidogrel Clopidogrel The serum concentration of Clopidogrel can be increased when it is combined with Vemurafenib.
Erythromycin and Sulfisoxazole Erythromycin and Sulfisoxazole The risk or severity of QTc prolongation can be increased when Vemurafenib is combined with Erythromycin.
Estrogen and Progestin (Oral Contraceptives) Estrogen and Progestin (Oral Contraceptives) The serum concentration of Conjugated estrogens can be increased when it is combined with Vemurafenib.
Fenofibrate Fenofibrate The metabolism of Fenofibrate can be decreased when combined with Vemurafenib.
Methylergonovine Methylergonovine The metabolism of Vemurafenib can be decreased when combined with Methylergometrine.
Miglitol Miglitol The therapeutic efficacy of Miglitol can be increased when used in combination with Vemurafenib.
Paregoric Paregoric The serum concentration of Morphine can be increased when it is combined with Vemurafenib.
Penbutolol Penbutolol The risk or severity of QTc prolongation can be increased when Vemurafenib is combined with Acebutolol.
Ranitidine Ranitidine The serum concentration of Ranitidine can be increased when it is combined with Vemurafenib.
Reserpine Reserpine The serum concentration of Vemurafenib can be increased when it is combined with Reserpine.
Sumatriptan Sumatriptan Vemurafenib may decrease the excretion rate of Sumatriptan which could result in a higher serum level.
Tacrolimus Tacrolimus The risk or severity of QTc prolongation can be increased when Tacrolimus is combined with Vemurafenib.
Tizanidine Tizanidine The serum concentration of Tizanidine can be increased when it is combined with Vemurafenib.
Triamcinolone Triamcinolone The metabolism of Vemurafenib can be increased when combined with Triamcinolone.
Zolmitriptan Zolmitriptan The serum concentration of Zolmitriptan can be increased when it is combined with Vemurafenib.
Doxycycline Injection Doxycycline Injection The metabolism of Vemurafenib can be decreased when combined with Doxycycline.
Famotidine Injection Famotidine Injection The risk or severity of QTc prolongation can be increased when Famotidine is combined with Vemurafenib.
Fluconazole Injection Fluconazole Injection The risk or severity of QTc prolongation can be increased when Fluconazole is combined with Vemurafenib.
Foscarnet Injection Foscarnet Injection The risk or severity of QTc prolongation can be increased when Foscarnet is combined with Vemurafenib.
Hydromorphone Injection Hydromorphone Injection The metabolism of Hydromorphone can be decreased when combined with Vemurafenib.
Levofloxacin Injection Levofloxacin Injection The risk or severity of QTc prolongation can be increased when Levofloxacin is combined with Vemurafenib.
Meperidine Injection Meperidine Injection The metabolism of Meperidine can be increased when combined with Vemurafenib.
Methylprednisolone Injection Methylprednisolone Injection The metabolism of Vemurafenib can be increased when combined with Methylprednisolone.
Metoclopramide Injection Metoclopramide Injection The serum concentration of Vemurafenib can be increased when it is combined with Metoclopramide.
Metronidazole Injection Metronidazole Injection The risk or severity of QTc prolongation can be increased when Metronidazole is combined with Vemurafenib.
Morphine Injection Morphine Injection The serum concentration of Morphine can be increased when it is combined with Vemurafenib.
Zidovudine Injection Zidovudine Injection Vemurafenib may decrease the excretion rate of Zidovudine which could result in a higher serum level.
Altretamine Altretamine The metabolism of Amphetamine can be decreased when combined with Vemurafenib.
Cyclosporine Cyclosporine The serum concentration of Cyclosporine can be increased when it is combined with Vemurafenib.
Ondansetron Ondansetron The risk or severity of QTc prolongation can be increased when Vemurafenib is combined with Ondansetron.
Granisetron Granisetron The risk or severity of QTc prolongation can be increased when Granisetron is combined with Vemurafenib.
Torsemide Torsemide The metabolism of Torasemide can be decreased when combined with Vemurafenib.
Olanzapine Olanzapine The risk or severity of QTc prolongation can be increased when Vemurafenib is combined with Olanzapine.
Alosetron Alosetron The serum concentration of Alosetron can be increased when it is combined with Vemurafenib.
Dofetilide Dofetilide The metabolism of Dofetilide can be increased when combined with Vemurafenib.
Hydroxychloroquine Hydroxychloroquine The risk or severity of QTc prolongation can be increased when Vemurafenib is combined with Hydroxychloroquine.
Meloxicam Meloxicam The metabolism of Meloxicam can be decreased when combined with Vemurafenib.
Orlistat Orlistat The metabolism of Vemurafenib can be increased when combined with Orlistat.
Oxcarbazepine Oxcarbazepine The metabolism of Vemurafenib can be increased when combined with Oxcarbazepine.
Pantoprazole Pantoprazole Pantoprazole may decrease the excretion rate of Vemurafenib which could result in a higher serum level.
Sevelamer Sevelamer Sevelamer can cause a decrease in the absorption of Vemurafenib resulting in a reduced serum concentration and potentially a decrease in efficacy.
Telmisartan Telmisartan Telmisartan may decrease the excretion rate of Vemurafenib which could result in a higher serum level.
Anakinra Anakinra The metabolism of Vemurafenib can be increased when combined with Anakinra.
Desloratadine Desloratadine The risk or severity of QTc prolongation can be increased when Desloratadine is combined with Vemurafenib.
Trimipramine Trimipramine The risk or severity of QTc prolongation can be increased when Vemurafenib is combined with Trimipramine.
Etanercept Injection Etanercept Injection The metabolism of Vemurafenib can be increased when combined with Etanercept.
Modafinil Modafinil The metabolism of Vemurafenib can be increased when combined with Modafinil.
Tenofovir Tenofovir The serum concentration of Tenofovir can be increased when it is combined with Vemurafenib.
Sirolimus Sirolimus The serum concentration of Sirolimus can be increased when it is combined with Vemurafenib.
Epinephrine Injection Epinephrine Injection The metabolism of Vemurafenib can be decreased when combined with Epinephrine.
Escitalopram Escitalopram The risk or severity of QTc prolongation can be increased when Escitalopram is combined with Vemurafenib.
Zonisamide Zonisamide The risk or severity of QTc prolongation can be increased when Zonisamide is combined with Vemurafenib.
Adalimumab Injection Adalimumab Injection The metabolism of Vemurafenib can be increased when combined with Adalimumab.
Aripiprazole Aripiprazole The risk or severity of QTc prolongation can be increased when Vemurafenib is combined with Aripiprazole.
Atomoxetine Atomoxetine The metabolism of Atomoxetine can be decreased when combined with Vemurafenib.
Ezetimibe Ezetimibe Vemurafenib may decrease the excretion rate of Ezetimibe which could result in a higher serum level.
Teriparatide Injection Teriparatide Injection The therapeutic efficacy of Teriparatide can be decreased when used in combination with Vemurafenib.
Atazanavir Atazanavir The risk or severity of QTc prolongation can be increased when Vemurafenib is combined with Atazanavir.
Almotriptan Almotriptan The metabolism of Almotriptan can be decreased when combined with Vemurafenib.
Eletriptan Eletriptan The metabolism of Eletriptan can be decreased when combined with Vemurafenib.
Mefloquine Mefloquine The risk or severity of QTc prolongation can be increased when Vemurafenib is combined with Mefloquine.
Rosuvastatin Rosuvastatin The metabolism of Rosuvastatin can be decreased when combined with Vemurafenib.
Vardenafil Vardenafil The serum concentration of Vardenafil can be increased when it is combined with Vemurafenib.
Alfuzosin Alfuzosin The risk or severity of QTc prolongation can be increased when Alfuzosin is combined with Vemurafenib.
Aprepitant Aprepitant The metabolism of Vemurafenib can be decreased when combined with Aprepitant.
Tegaserod Tegaserod The serum concentration of Tegaserod can be increased when it is combined with Vemurafenib.
Frovatriptan Frovatriptan The serum concentration of Frovatriptan can be increased when it is combined with Vemurafenib.
Gemifloxacin Gemifloxacin The risk or severity of QTc prolongation can be increased when Gemifloxacin is combined with Vemurafenib.
Progesterone Progesterone The metabolism of Vemurafenib can be increased when combined with Progesterone.
Apomorphine Injection Apomorphine Injection The risk or severity of QTc prolongation can be increased when Apomorphine is combined with Vemurafenib.
Darbepoetin Alfa Injection Darbepoetin Alfa Injection The risk or severity of Thrombosis can be increased when Darbepoetin alfa is combined with Vemurafenib.
Infliximab Injection Infliximab Injection The metabolism of Vemurafenib can be increased when combined with Infliximab.
Protriptyline Protriptyline The risk or severity of QTc prolongation can be increased when Vemurafenib is combined with Protriptyline.
Rifaximin Rifaximin The serum concentration of Rifaximin can be increased when it is combined with Vemurafenib.
Duloxetine Duloxetine The serum concentration of Duloxetine can be increased when it is combined with Vemurafenib.
Norethindrone Norethindrone The metabolism of Norethisterone can be decreased when combined with Vemurafenib.
Bosentan Bosentan The metabolism of Bosentan can be increased when combined with Vemurafenib.
Cinacalcet Cinacalcet The serum concentration of Cinacalcet can be increased when it is combined with Vemurafenib.
Erlotinib Erlotinib The serum concentration of Erlotinib can be decreased when it is combined with Vemurafenib.
Eszopiclone Eszopiclone The serum concentration of Eszopiclone can be decreased when it is combined with Vemurafenib.
Insulin Aspart (rDNA Origin) Injection Insulin Aspart (rDNA Origin) Injection The therapeutic efficacy of Insulin aspart can be increased when used in combination with Vemurafenib.
Solifenacin Solifenacin The risk or severity of QTc prolongation can be increased when Solifenacin is combined with Vemurafenib.
Voriconazole Voriconazole The risk or severity of QTc prolongation can be increased when Voriconazole is combined with Vemurafenib.
Dextroamphetamine Dextroamphetamine The metabolism of Amphetamine can be decreased when combined with Vemurafenib.
Entecavir Entecavir The serum concentration of Entecavir can be increased when it is combined with Vemurafenib.
Pramlintide Injection Pramlintide Injection The therapeutic efficacy of Pramlintide can be increased when used in combination with Vemurafenib.
Exenatide Injection Exenatide Injection The therapeutic efficacy of Exenatide can be increased when used in combination with Vemurafenib.
Ibandronate Ibandronate The risk or severity of QTc prolongation can be increased when Ibandronate is combined with Vemurafenib.
Ramelteon Ramelteon The serum concentration of Ramelteon can be increased when it is combined with Vemurafenib.
Darifenacin Darifenacin The metabolism of Darifenacin can be decreased when combined with Vemurafenib.
Pregabalin Pregabalin The risk or severity of QTc prolongation can be increased when Pregabalin is combined with Vemurafenib.
Deferasirox Deferasirox The metabolism of Vemurafenib can be increased when combined with Deferasirox.
Tipranavir Tipranavir The serum concentration of Tipranavir can be increased when it is combined with Vemurafenib.
Felbamate Felbamate The risk or severity of QTc prolongation can be increased when Felbamate is combined with Vemurafenib.
Insulin Detemir (rDNA Origin) Injection Insulin Detemir (rDNA Origin) Injection The therapeutic efficacy of Insulin detemir can be increased when used in combination with Vemurafenib.
Ranolazine Ranolazine The metabolism of Vemurafenib can be increased when combined with Ranolazine.
Abatacept Injection Abatacept Injection The metabolism of Vemurafenib can be increased when combined with Abatacept.
Rasagiline Rasagiline The serum concentration of Rasagiline can be increased when it is combined with Vemurafenib.
Imatinib Imatinib The serum concentration of Vemurafenib can be increased when it is combined with Imatinib.
Sitagliptin Sitagliptin The serum concentration of Sitagliptin can be increased when it is combined with Vemurafenib.
Gefitinib Gefitinib The metabolism of Vemurafenib can be decreased when combined with Gefitinib.
Albuterol Albuterol The risk or severity of QTc prolongation can be increased when Salbutamol is combined with Vemurafenib.
Paliperidone Paliperidone The risk or severity of QTc prolongation can be increased when Vemurafenib is combined with Paliperidone.
Bortezomib Bortezomib The serum concentration of Bortezomib can be increased when it is combined with Vemurafenib.
Clofarabine Injection Clofarabine Injection Vemurafenib may decrease the excretion rate of Clofarabine which could result in a higher serum level.
Insulin Glulisine (rDNA origin) Injection Insulin Glulisine (rDNA origin) Injection The therapeutic efficacy of Insulin glulisine can be increased when used in combination with Vemurafenib.
Oxaliplatin Injection Oxaliplatin Injection The risk or severity of QTc prolongation can be increased when Oxaliplatin is combined with Vemurafenib.
Posaconazole Posaconazole The serum concentration of Posaconazole can be increased when it is combined with Vemurafenib.
Primaquine Primaquine The risk or severity of QTc prolongation can be increased when Vemurafenib is combined with Primaquine.
Darunavir Darunavir The serum concentration of Vemurafenib can be increased when it is combined with Darunavir.
Pemetrexed Injection Pemetrexed Injection The serum concentration of Pemetrexed can be increased when it is combined with Vemurafenib.
Dimenhydrinate Dimenhydrinate The risk or severity of QTc prolongation can be increased when Dimenhydrinate is combined with Vemurafenib.
Lisdexamfetamine Lisdexamfetamine The metabolism of Lisdexamfetamine can be decreased when combined with Vemurafenib.
Retapamulin Retapamulin The metabolism of Retapamulin can be increased when combined with Vemurafenib.
Vorinostat Vorinostat The risk or severity of QTc prolongation can be increased when Vorinostat is combined with Vemurafenib.
Sorafenib Sorafenib The serum concentration of Vemurafenib can be increased when it is combined with Sorafenib.
Sunitinib Sunitinib The risk or severity of QTc prolongation can be increased when Sunitinib is combined with Vemurafenib.
Dronabinol Dronabinol Dronabinol may decrease the excretion rate of Vemurafenib which could result in a higher serum level.
Lapatinib Lapatinib The risk or severity of QTc prolongation can be increased when Lapatinib is combined with Vemurafenib.
Levocetirizine Levocetirizine The risk or severity of QTc prolongation can be increased when Levocetirizine is combined with Vemurafenib.
Dasatinib Dasatinib The serum concentration of Dasatinib can be increased when it is combined with Vemurafenib.
Mexiletine Mexiletine The serum concentration of Mexiletine can be increased when it is combined with Vemurafenib.
Armodafinil Armodafinil The metabolism of Vemurafenib can be increased when combined with Armodafinil.
Ivermectin Ivermectin The metabolism of Ivermectin can be increased when combined with Vemurafenib.
Temsirolimus Temsirolimus The serum concentration of Temsirolimus can be increased when it is combined with Vemurafenib.
Nilotinib Nilotinib The metabolism of Vemurafenib can be decreased when combined with Nilotinib.
Toremifene Toremifene The serum concentration of Toremifene can be increased when it is combined with Vemurafenib.
Bexarotene Bexarotene The metabolism of Bexarotene can be increased when combined with Vemurafenib.
Budesonide Budesonide The metabolism of Vemurafenib can be increased when combined with Budesonide.
Chloramphenicol Injection Chloramphenicol Injection The metabolism of Vemurafenib can be decreased when combined with Chloramphenicol.
Etravirine Etravirine The metabolism of Etravirine can be increased when combined with Vemurafenib.
Arsenic Trioxide Injection Arsenic Trioxide Injection The risk or severity of QTc prolongation can be increased when Arsenic trioxide is combined with Vemurafenib.
Mitoxantrone Injection Mitoxantrone Injection The metabolism of Mitoxantrone can be decreased when combined with Vemurafenib.
Desvenlafaxine Desvenlafaxine The metabolism of Vemurafenib can be decreased when combined with Desvenlafaxine.
Cevimeline Cevimeline The metabolism of Cevimeline can be decreased when combined with Vemurafenib.
Nebivolol Nebivolol The metabolism of Nebivolol can be decreased when combined with Vemurafenib.
Tretinoin Tretinoin The metabolism of Tretinoin can be decreased when combined with Vemurafenib.
Bendamustine Injection Bendamustine Injection The serum concentration of Bendamustine can be increased when it is combined with Vemurafenib.
Pilocarpine Pilocarpine The metabolism of Vemurafenib can be decreased when combined with Pilocarpine.
Flecainide Flecainide The serum concentration of Flecainide can be increased when it is combined with Vemurafenib.
Certolizumab Injection Certolizumab Injection The metabolism of Vemurafenib can be increased when combined with Certolizumab pegol.
Ixabepilone Injection Ixabepilone Injection The metabolism of Ixabepilone can be increased when combined with Vemurafenib.
Irinotecan Injection Irinotecan Injection The metabolism of Irinotecan can be increased when combined with Vemurafenib.
Praziquantel Praziquantel The serum concentration of Praziquantel can be increased when it is combined with Vemurafenib.
Mitotane Mitotane The metabolism of Vemurafenib can be increased when combined with Mitotane.
Rufinamide Rufinamide The metabolism of Rufinamide can be increased when combined with Vemurafenib.
Silodosin Silodosin The serum concentration of Silodosin can be increased when it is combined with Vemurafenib.
Midazolam Midazolam The metabolism of Vemurafenib can be decreased when combined with Midazolam.
Eltrombopag Eltrombopag The serum concentration of Eltrombopag can be increased when it is combined with Vemurafenib.
Milnacipran Milnacipran The metabolism of Milnacipran can be increased when combined with Vemurafenib.
Fesoterodine Fesoterodine The metabolism of Fesoterodine can be decreased when combined with Vemurafenib.
Degarelix Injection Degarelix Injection The risk or severity of QTc prolongation can be increased when Degarelix is combined with Vemurafenib.
Betaxolol Betaxolol The serum concentration of Betaxolol can be increased when it is combined with Vemurafenib.
Iloperidone Iloperidone The risk or severity of QTc prolongation can be increased when Iloperidone is combined with Vemurafenib.
Prasugrel Prasugrel The metabolism of Prasugrel can be decreased when combined with Vemurafenib.
Lacosamide Lacosamide The metabolism of Lacosamide can be decreased when combined with Vemurafenib.
Everolimus Everolimus The serum concentration of Everolimus can be increased when it is combined with Vemurafenib.
Tolvaptan (low blood sodium) Tolvaptan (low blood sodium) The serum concentration of Tolvaptan can be increased when it is combined with Vemurafenib.
Dronedarone Dronedarone Vemurafenib may increase the QTc-prolonging activities of Dronedarone.
Pralatrexate Injection Pralatrexate Injection Vemurafenib may decrease the excretion rate of Pralatrexate which could result in a higher serum level.
Palonosetron Injection Palonosetron Injection The metabolism of Palonosetron can be decreased when combined with Vemurafenib.
Saxagliptin Saxagliptin The therapeutic efficacy of Saxagliptin can be increased when used in combination with Vemurafenib.
Telavancin Injection Telavancin Injection The risk or severity of QTc prolongation can be increased when Telavancin is combined with Vemurafenib.
Romidepsin Injection Romidepsin Injection The serum concentration of Romidepsin can be increased when it is combined with Vemurafenib.
Tapentadol Tapentadol The metabolism of Tapentadol can be decreased when combined with Vemurafenib.
Topotecan Topotecan The serum concentration of Topotecan can be increased when it is combined with Vemurafenib.
Golimumab Injection Golimumab Injection The metabolism of Vemurafenib can be increased when combined with Golimumab.
Pazopanib Pazopanib The serum concentration of Pazopanib can be increased when it is combined with Vemurafenib.
Asenapine Asenapine The risk or severity of QTc prolongation can be increased when Vemurafenib is combined with Asenapine.
Pitavastatin Pitavastatin Vemurafenib may decrease the excretion rate of Pitavastatin which could result in a higher serum level.
Albendazole Albendazole The serum concentration of Albendazole can be increased when it is combined with Vemurafenib.
Ulipristal Ulipristal The metabolism of Ulipristal can be increased when combined with Vemurafenib.
Levonorgestrel Levonorgestrel The metabolism of Levonorgestrel can be increased when combined with Vemurafenib.
Oxymorphone Oxymorphone The metabolism of Oxymorphone can be decreased when combined with Vemurafenib.
Liraglutide Injection Liraglutide Injection The therapeutic efficacy of Liraglutide can be increased when used in combination with Vemurafenib.
Tocilizumab Injection Tocilizumab Injection The metabolism of Vemurafenib can be increased when combined with Tocilizumab.
Eribulin Injection Eribulin Injection The risk or severity of QTc prolongation can be increased when Eribulin is combined with Vemurafenib.
Cabazitaxel Injection Cabazitaxel Injection The serum concentration of Cabazitaxel can be increased when it is combined with Vemurafenib.
Lurasidone Lurasidone The risk or severity of QTc prolongation can be increased when Vemurafenib is combined with Lurasidone.
Acetaminophen Injection Acetaminophen Injection The serum concentration of Acetaminophen can be increased when it is combined with Vemurafenib.
Vilazodone Vilazodone The metabolism of Vilazodone can be decreased when combined with Vemurafenib.
Ipilimumab Injection Ipilimumab Injection Ipilimumab may increase the hepatotoxic activities of Vemurafenib.
Denileukin Diftitox Injection Denileukin Diftitox Injection The metabolism of Vemurafenib can be decreased when combined with Aldesleukin.
Terbutaline Injection Terbutaline Injection The risk or severity of QTc prolongation can be increased when Terbutaline is combined with Vemurafenib.
Busulfan Injection Busulfan Injection The metabolism of Busulfan can be increased when combined with Vemurafenib.
Roflumilast Roflumilast The metabolism of Roflumilast can be decreased when combined with Vemurafenib.
Linagliptin Linagliptin The serum concentration of Linagliptin can be increased when it is combined with Vemurafenib.
Rilpivirine Rilpivirine The risk or severity of QTc prolongation can be increased when Vemurafenib is combined with Rilpivirine.
Telaprevir Telaprevir The serum concentration of Glecaprevir can be increased when it is combined with Vemurafenib.
Potassium Iodide Potassium Iodide The therapeutic efficacy of Potassium Iodide can be decreased when used in combination with Vemurafenib.
Cyclophosphamide Injection Cyclophosphamide Injection The metabolism of Cyclophosphamide can be increased when combined with Vemurafenib.
Triptorelin Injection Triptorelin Injection The risk or severity of QTc prolongation can be increased when Triptorelin is combined with Vemurafenib.
Rivaroxaban Rivaroxaban The serum concentration of Rivaroxaban can be increased when it is combined with Vemurafenib.
Ticagrelor Ticagrelor The serum concentration of Ticagrelor can be increased when it is combined with Vemurafenib.
Brentuximab Vedotin Injection Brentuximab Vedotin Injection The serum concentration of Brentuximab vedotin can be increased when it is combined with Vemurafenib.
Ruxolitinib Ruxolitinib The metabolism of Ruxolitinib can be increased when combined with Vemurafenib.
Vandetanib Vandetanib The metabolism of Vemurafenib can be increased when combined with Vandetanib.
Clobazam Clobazam The serum concentration of Clobazam can be increased when it is combined with Vemurafenib.
Vismodegib Vismodegib Vismodegib may decrease the excretion rate of Vemurafenib which could result in a higher serum level.
Ivacaftor Ivacaftor The metabolism of Vemurafenib can be decreased when combined with Ivacaftor.
Axitinib Axitinib The serum concentration of Axitinib can be increased when it is combined with Vemurafenib.
Crizotinib Crizotinib The serum concentration of Crizotinib can be increased when it is combined with Vemurafenib.
Cabergoline Cabergoline The metabolism of Vemurafenib can be decreased when combined with Cabergoline.
Naloxone Injection Naloxone Injection The metabolism of Vemurafenib can be decreased when combined with Naloxone.
Ambrisentan Ambrisentan The serum concentration of Ambrisentan can be increased when it is combined with Vemurafenib.
Carfilzomib Injection Carfilzomib Injection The serum concentration of Vemurafenib can be increased when it is combined with Carfilzomib.
Enzalutamide Enzalutamide The metabolism of Vemurafenib can be increased when combined with Enzalutamide.
Mirabegron Mirabegron The serum concentration of Mirabegron can be increased when it is combined with Vemurafenib.
Regorafenib Regorafenib The metabolism of Vemurafenib can be decreased when combined with Regorafenib.
Bosutinib Bosutinib The serum concentration of Bosutinib can be increased when it is combined with Vemurafenib.
Corticotropin, Repository Injection Corticotropin, Repository Injection The metabolism of Vemurafenib can be increased when combined with Corticotropin.
Teriflunomide Teriflunomide Teriflunomide may decrease the excretion rate of Vemurafenib which could result in a higher serum level.
Lorcaserin Lorcaserin The therapeutic efficacy of Mecasermin can be increased when used in combination with Vemurafenib.
Cabozantinib (thyroid cancer) Cabozantinib (thyroid cancer) The metabolism of Cabozantinib can be decreased when combined with Vemurafenib.
Bedaquiline Bedaquiline The risk or severity of QTc prolongation can be increased when Bedaquiline is combined with Vemurafenib.
Alogliptin Alogliptin The therapeutic efficacy of Alogliptin can be increased when used in combination with Vemurafenib.
Ponatinib Ponatinib The serum concentration of Vemurafenib can be increased when it is combined with Ponatinib.
Pomalidomide Pomalidomide The serum concentration of Pomalidomide can be increased when it is combined with Vemurafenib.
Ado-trastuzumab Emtansine Injection Ado-trastuzumab Emtansine Injection The serum concentration of Trastuzumab emtansine can be increased when it is combined with Vemurafenib.
Apixaban Apixaban The serum concentration of Apixaban can be increased when it is combined with Vemurafenib.
Canagliflozin Canagliflozin The serum concentration of Canagliflozin can be increased when it is combined with Vemurafenib.
Dabrafenib Dabrafenib The serum concentration of Dabrafenib can be increased when it is combined with Vemurafenib.
Ospemifene Ospemifene The metabolism of Ospemifene can be decreased when combined with Vemurafenib.
Trametinib Trametinib The metabolism of Vemurafenib can be increased when combined with Trametinib.
Dolutegravir Dolutegravir The serum concentration of Dolutegravir can be increased when it is combined with Vemurafenib.
Afatinib Afatinib The serum concentration of Afatinib can be increased when it is combined with Vemurafenib.
Levomilnacipran Levomilnacipran The metabolism of Levomilnacipran can be increased when combined with Vemurafenib.
Vortioxetine Vortioxetine The metabolism of Vortioxetine can be decreased when combined with Vemurafenib.
Perampanel Perampanel The metabolism of Perampanel can be increased when combined with Vemurafenib.
Ibrutinib Ibrutinib The metabolism of Ibrutinib can be decreased when combined with Vemurafenib.
Lomitapide Lomitapide The metabolism of Vemurafenib can be decreased when combined with Lomitapide.
Ketorolac Injection Ketorolac Injection The metabolism of Ketorolac can be decreased when combined with Vemurafenib.
Simeprevir Simeprevir The serum concentration of Simeprevir can be increased when it is combined with Vemurafenib.
Sofosbuvir Sofosbuvir The serum concentration of Sofosbuvir can be increased when it is combined with Vemurafenib.
Dapagliflozin Dapagliflozin The serum concentration of Dapagliflozin can be increased when it is combined with Vemurafenib.
Apremilast Apremilast The serum concentration of Apremilast can be increased when it is combined with Vemurafenib.
Ceritinib Ceritinib The serum concentration of Ceritinib can be increased when it is combined with Vemurafenib.
Siltuximab Injection Siltuximab Injection The metabolism of Vemurafenib can be increased when combined with Siltuximab.
Albiglutide Injection Albiglutide Injection The therapeutic efficacy of Albiglutide can be increased when used in combination with Vemurafenib.
Eslicarbazepine Eslicarbazepine The metabolism of Vemurafenib can be increased when combined with Eslicarbazepine.
Belinostat Injection Belinostat Injection The serum concentration of Belinostat can be increased when it is combined with Vemurafenib.
Idelalisib Idelalisib The serum concentration of Idelalisib can be increased when it is combined with Vemurafenib.
Testosterone Injection Testosterone Injection The metabolism of Testosterone can be increased when combined with Vemurafenib.
Oritavancin Injection Oritavancin Injection The metabolism of Vemurafenib can be increased when combined with Oritavancin.
Empagliflozin Empagliflozin The therapeutic efficacy of Empagliflozin can be increased when used in combination with Vemurafenib.
Vorapaxar Vorapaxar The serum concentration of Vemurafenib can be increased when it is combined with Vorapaxar.
Hydrocodone Hydrocodone The metabolism of Hydrocodone can be increased when combined with Vemurafenib.
Suvorexant Suvorexant The serum concentration of Vemurafenib can be increased when it is combined with Suvorexant.
Dulaglutide Injection Dulaglutide Injection The therapeutic efficacy of Dulaglutide can be increased when used in combination with Vemurafenib.
Edoxaban Edoxaban The serum concentration of Edoxaban can be increased when it is combined with Vemurafenib.
Olaparib Olaparib The metabolism of Vemurafenib can be decreased when combined with Olaparib.
Methamphetamine Methamphetamine The metabolism of Metamfetamine can be decreased when combined with Vemurafenib.
Tasimelteon Tasimelteon The serum concentration of Tasimelteon can be increased when it is combined with Vemurafenib.
Riociguat Riociguat Vemurafenib may decrease the excretion rate of Riociguat which could result in a higher serum level.
Lanreotide Injection Lanreotide Injection The metabolism of Vemurafenib can be decreased when combined with Lanreotide.
Pirfenidone Pirfenidone The serum concentration of Pirfenidone can be increased when it is combined with Vemurafenib.
Nintedanib Nintedanib The serum concentration of Nintedanib can be increased when it is combined with Vemurafenib.
Secukinumab Injection Secukinumab Injection The metabolism of Vemurafenib can be increased when combined with Secukinumab.
Risperidone Injection Risperidone Injection The risk or severity of QTc prolongation can be increased when Vemurafenib is combined with Risperidone.
Palbociclib Palbociclib The metabolism of Palbociclib can be decreased when combined with Vemurafenib.
Insulin Human Inhalation Insulin Human Inhalation The therapeutic efficacy of Insulin human can be increased when used in combination with Vemurafenib.
Lenvatinib Lenvatinib The serum concentration of Lenvatinib can be increased when it is combined with Vemurafenib.
Naloxegol Naloxegol The serum concentration of Naloxegol can be increased when it is combined with Vemurafenib.
Panobinostat Panobinostat The serum concentration of Panobinostat can be increased when it is combined with Vemurafenib.
Haloperidol Injection Haloperidol Injection The risk or severity of QTc prolongation can be increased when Vemurafenib is combined with Haloperidol.
Ivabradine Ivabradine The risk or severity of QTc prolongation can be increased when Vemurafenib is combined with Ivabradine.
Isavuconazonium Injection Isavuconazonium Injection The serum concentration of Vemurafenib can be increased when it is combined with Isavuconazonium.
Sonidegib Sonidegib The metabolism of Sonidegib can be increased when combined with Vemurafenib.
Flibanserin Flibanserin The serum concentration of Vemurafenib can be increased when it is combined with Flibanserin.
Rolapitant Rolapitant The serum concentration of Vemurafenib can be increased when it is combined with Rolapitant.
Prednisolone Prednisolone The metabolism of Vemurafenib can be increased when combined with Prednisolone.
Daclatasvir Daclatasvir The serum concentration of Vemurafenib can be increased when it is combined with Daclatasvir.
Brexpiprazole Brexpiprazole The metabolism of Brexpiprazole can be decreased when combined with Vemurafenib.
Ziprasidone Injection Ziprasidone Injection The risk or severity of QTc prolongation can be increased when Vemurafenib is combined with Ziprasidone.
Cariprazine Cariprazine The metabolism of Cariprazine can be decreased when combined with Vemurafenib.
Insulin Degludec (rDNA Origin) Injection Insulin Degludec (rDNA Origin) Injection The therapeutic efficacy of Insulin degludec can be increased when used in combination with Vemurafenib.
Cobimetinib Cobimetinib The serum concentration of Cobimetinib can be increased when it is combined with Vemurafenib.
Trabectedin Injection Trabectedin Injection The metabolism of Trabectedin can be increased when combined with Vemurafenib.
Osimertinib Osimertinib The serum concentration of Osimertinib can be increased when it is combined with Vemurafenib.
Alectinib Alectinib The metabolism of Vemurafenib can be increased when combined with Alectinib.
Ixazomib Ixazomib The metabolism of Ixazomib can be increased when combined with Vemurafenib.
Rifapentine Rifapentine The metabolism of Vemurafenib can be increased when combined with Rifapentine.
Lesinurad Lesinurad The metabolism of Lesinurad can be increased when combined with Vemurafenib.
Amphotericin B Liposomal Injection Amphotericin B Liposomal Injection The metabolism of Vemurafenib can be decreased when combined with Amphotericin B.
Dexamethasone Injection Dexamethasone Injection The metabolism of Vemurafenib can be increased when combined with Dexamethasone.
Brivaracetam Injection Brivaracetam Injection The metabolism of Brivaracetam can be decreased when combined with Vemurafenib.
Venetoclax Venetoclax The serum concentration of Venetoclax can be increased when it is combined with Vemurafenib.
Cobicistat Cobicistat The metabolism of Vemurafenib can be decreased when combined with Cobicistat.
Selexipag Selexipag The serum concentration of Selexipag can be increased when it is combined with Vemurafenib.
Diphenhydramine Injection Diphenhydramine Injection The risk or severity of QTc prolongation can be increased when Diphenhydramine is combined with Vemurafenib.
Rucaparib Rucaparib The serum concentration of Rucaparib can be increased when it is combined with Vemurafenib.
Lixisenatide Injection Lixisenatide Injection The therapeutic efficacy of Lixisenatide can be increased when used in combination with Vemurafenib.
Ribociclib Ribociclib The metabolism of Ribociclib can be decreased when combined with Vemurafenib.
Parathyroid Hormone Injection Parathyroid Hormone Injection The therapeutic efficacy of Parathyroid hormone can be decreased when used in combination with Vemurafenib.
Brigatinib Brigatinib The metabolism of Brigatinib can be increased when combined with Vemurafenib.
Doxepin (Insomnia) Doxepin (Insomnia) The serum concentration of Doxepin can be increased when it is combined with Vemurafenib.
Deutetrabenazine Deutetrabenazine The risk or severity of QTc prolongation can be increased when Vemurafenib is combined with Deutetrabenazine.
Valbenazine Valbenazine The metabolism of Valbenazine can be decreased when combined with Vemurafenib.
Deflazacort Deflazacort The metabolism of Vemurafenib can be increased when combined with Deflazacort.
Safinamide Safinamide Safinamide may decrease the excretion rate of Vemurafenib which could result in a higher serum level.
Sarilumab Injection Sarilumab Injection The metabolism of Vemurafenib can be increased when combined with Sarilumab.
Midostaurin Midostaurin The metabolism of Vemurafenib can be increased when combined with Midostaurin.
Neratinib Neratinib The serum concentration of Vemurafenib can be increased when it is combined with Neratinib.
Abaloparatide Injection Abaloparatide Injection The therapeutic efficacy of Abaloparatide can be decreased when used in combination with Vemurafenib.
Enasidenib Enasidenib The serum concentration of Enasidenib can be increased when it is combined with Vemurafenib.
Inotuzumab Ozogamicin Injection Inotuzumab Ozogamicin Injection The serum concentration of Inotuzumab ozogamicin can be increased when it is combined with Vemurafenib.
Aprepitant/Fosaprepitant Injection Aprepitant/Fosaprepitant Injection The metabolism of Fosaprepitant can be increased when combined with Vemurafenib.
Copanlisib Injection Copanlisib Injection The serum concentration of Copanlisib can be increased when it is combined with Vemurafenib.
Delafloxacin Delafloxacin The risk or severity of QTc prolongation can be increased when Delafloxacin is combined with Vemurafenib.
Abemaciclib Abemaciclib The metabolism of Abemaciclib can be increased when combined with Vemurafenib.
Betrixaban Betrixaban The serum concentration of Betrixaban can be increased when it is combined with Vemurafenib.
Acalabrutinib Acalabrutinib The metabolism of Acalabrutinib can be increased when combined with Vemurafenib.
Letermovir Letermovir The metabolism of Vemurafenib can be decreased when combined with Letermovir.
Semaglutide Injection Semaglutide Injection The therapeutic efficacy of Semaglutide can be increased when used in combination with Vemurafenib.
Tetrabenazine Tetrabenazine The risk or severity of QTc prolongation can be increased when Tetrabenazine is combined with Vemurafenib.
Ertugliflozin Ertugliflozin The serum concentration of Ertugliflozin can be increased when it is combined with Vemurafenib.
Buprenorphine Injection Buprenorphine Injection The metabolism of Vemurafenib can be decreased when combined with Buprenorphine.
Apalutamide Apalutamide The serum concentration of Vemurafenib can be decreased when it is combined with Apalutamide.
Fostamatinib Fostamatinib The metabolism of Vemurafenib can be decreased when combined with Fostamatinib.
Avatrombopag Avatrombopag The serum concentration of Avatrombopag can be increased when it is combined with Vemurafenib.
Baricitinib Baricitinib The serum concentration of Baricitinib can be increased when it is combined with Vemurafenib.
Lofexidine Lofexidine The serum concentration of Lofexidine can be increased when it is combined with Vemurafenib.
Eliglustat Eliglustat The serum concentration of Eliglustat can be increased when it is combined with Vemurafenib.
Encorafenib Encorafenib The risk or severity of QTc prolongation can be increased when Vemurafenib is combined with Encorafenib.
Binimetinib Binimetinib The serum concentration of Binimetinib can be increased when it is combined with Vemurafenib.
Ivosidenib Ivosidenib The serum concentration of Ivosidenib can be increased when it is combined with Vemurafenib.
Lusutrombopag Lusutrombopag The serum concentration of Lusutrombopag can be increased when it is combined with Vemurafenib.
Elagolix Elagolix The serum concentration of Elagolix can be increased when it is combined with Vemurafenib.
Tafenoquine Tafenoquine The risk or severity of QTc prolongation can be increased when Vemurafenib is combined with Tafenoquine.
Cannabidiol Cannabidiol Cannabidiol may decrease the excretion rate of Vemurafenib which could result in a higher serum level.
Dacomitinib Dacomitinib The serum concentration of Dacomitinib can be increased when it is combined with Vemurafenib.
Duvelisib Duvelisib The serum concentration of Duvelisib can be increased when it is combined with Vemurafenib.
Omadacycline Omadacycline The serum concentration of Omadacycline can be increased when it is combined with Vemurafenib.
Sarecycline Sarecycline The serum concentration of Vemurafenib can be increased when it is combined with Sarecycline.
Stiripentol Stiripentol The serum concentration of Stiripentol can be increased when it is combined with Vemurafenib.
Talazoparib Talazoparib The serum concentration of Talazoparib can be increased when it is combined with Vemurafenib.
Gilteritinib Gilteritinib The serum concentration of Gilteritinib can be increased when it is combined with Vemurafenib.
Glasdegib Glasdegib The serum concentration of Glasdegib can be increased when it is combined with Vemurafenib.
Lorlatinib Lorlatinib The metabolism of Lorlatinib can be decreased when combined with Vemurafenib.
Larotrectinib Larotrectinib The serum concentration of Larotrectinib can be increased when it is combined with Vemurafenib.
Methoxy Polyethylene Glycol-Epoetin Beta Injection Methoxy Polyethylene Glycol-Epoetin Beta Injection The risk or severity of Thrombosis can be increased when Methoxy polyethylene glycol-epoetin beta is combined with Vemurafenib.
Paclitaxel (with albumin) Injection Paclitaxel (with albumin) Injection The metabolism of Paclitaxel can be increased when combined with Vemurafenib.
Rifamycin Rifamycin The serum concentration of Rifamycin can be increased when it is combined with Vemurafenib.
Prucalopride Prucalopride The serum concentration of Prucalopride can be increased when it is combined with Vemurafenib.
Emapalumab-lzsg Injection Emapalumab-lzsg Injection The metabolism of Vemurafenib can be increased when combined with Emapalumab.
Siponimod Siponimod The metabolism of Siponimod can be increased when combined with Vemurafenib.
Acyclovir Ophthalmic Acyclovir Ophthalmic The serum concentration of Acyclovir can be increased when it is combined with Vemurafenib.
Erdafitinib Erdafitinib The serum concentration of Vemurafenib can be increased when it is combined with Erdafitinib.
Alpelisib Alpelisib The serum concentration of Alpelisib can be increased when it is combined with Vemurafenib.
Cladribine Cladribine Vemurafenib may decrease the excretion rate of Cladribine which could result in a higher serum level.
Darolutamide Darolutamide The serum concentration of Darolutamide can be increased when it is combined with Vemurafenib.
Triclabendazole Triclabendazole The serum concentration of Triclabendazole can be increased when it is combined with Vemurafenib.
Entrectinib Entrectinib The metabolism of Entrectinib can be increased when combined with Vemurafenib.
Pexidartinib Pexidartinib The metabolism of Pexidartinib can be increased when combined with Vemurafenib.
Istradefylline Istradefylline The serum concentration of Istradefylline can be increased when it is combined with Vemurafenib.
Pitolisant Pitolisant The serum concentration of Vemurafenib can be decreased when it is combined with Pitolisant.
Fedratinib Fedratinib The serum concentration of Fedratinib can be increased when it is combined with Vemurafenib.
Lefamulin Lefamulin Vemurafenib may increase the QTc-prolonging activities of Lefamulin.
Phenytoin Injection Phenytoin Injection The metabolism of Phenytoin can be decreased when combined with Vemurafenib.
Fosphenytoin Injection Fosphenytoin Injection The metabolism of Fosphenytoin can be decreased when combined with Vemurafenib.
Enfortumab vedotin-ejfv Injection Enfortumab vedotin-ejfv Injection The serum concentration of Enfortumab vedotin can be increased when it is combined with Vemurafenib.
Zanubrutinib Zanubrutinib The metabolism of Zanubrutinib can be increased when combined with Vemurafenib.
Voxelotor Voxelotor The serum concentration of Voxelotor can be increased when it is combined with Vemurafenib.
Avapritinib Avapritinib The metabolism of Avapritinib can be decreased when combined with Vemurafenib.
Lumateperone Lumateperone The serum concentration of Lumateperone can be decreased when it is combined with Vemurafenib.
Lasmiditan Lasmiditan The serum concentration of Vemurafenib can be increased when it is combined with Lasmiditan.
Ubrogepant Ubrogepant The serum concentration of Ubrogepant can be increased when it is combined with Vemurafenib.
Tazemetostat Tazemetostat The serum concentration of Tazemetostat can be increased when it is combined with Vemurafenib.
Cenobamate Cenobamate The serum concentration of Cenobamate can be decreased when it is combined with Vemurafenib.
Ozanimod Ozanimod Vemurafenib may decrease the excretion rate of Ozanimod which could result in a higher serum level.
Selumetinib Selumetinib The serum concentration of Selumetinib can be increased when it is combined with Vemurafenib.
Rimegepant Rimegepant The metabolism of Rimegepant can be increased when combined with Vemurafenib.
Tucatinib Tucatinib The serum concentration of Tucatinib can be increased when it is combined with Vemurafenib.
Remdesivir Injection Remdesivir Injection The serum concentration of Remdesivir can be increased when it is combined with Vemurafenib.
Ripretinib Ripretinib The serum concentration of Ripretinib can be increased when it is combined with Vemurafenib.
Selpercatinib Selpercatinib The serum concentration of Selpercatinib can be decreased when it is combined with Vemurafenib.
Capmatinib Capmatinib The serum concentration of Capmatinib can be decreased when it is combined with Vemurafenib.
Lemborexant Lemborexant The serum concentration of Lemborexant can be increased when it is combined with Vemurafenib.
Fostemsavir Fostemsavir The serum concentration of Vemurafenib can be increased when it is combined with Fostemsavir.
Octreotide Octreotide The risk or severity of QTc prolongation can be increased when Octreotide is combined with Vemurafenib.
Belantamab Mafodotin-blmf Injection Belantamab Mafodotin-blmf Injection The serum concentration of Belantamab mafodotin can be increased when it is combined with Vemurafenib.
Pralsetinib Pralsetinib The serum concentration of Pralsetinib can be increased when it is combined with Vemurafenib.
Satralizumab-mwge Injection Satralizumab-mwge Injection The serum concentration of Vemurafenib can be decreased when it is combined with Satralizumab.
Relugolix Relugolix The serum concentration of Relugolix can be increased when it is combined with Vemurafenib.
Progestin-Only (drospirenone) Oral Contraceptives Progestin-Only (drospirenone) Oral Contraceptives The metabolism of Drospirenone can be decreased when combined with Vemurafenib.
Vitamin E (Alpha-Tocopherol) Vitamin E (Alpha-Tocopherol) The metabolism of Vemurafenib can be increased when combined with Vitamin E.
Theophylline Theophylline The serum concentration of Theophylline can be increased when it is combined with Vemurafenib.
Indomethacin Indomethacin The metabolism of Indomethacin can be decreased when combined with Vemurafenib.
Mefenamic Acid Mefenamic Acid The metabolism of Mefenamic acid can be decreased when combined with Vemurafenib.
Naproxen Naproxen The serum concentration of Naproxen can be increased when it is combined with Vemurafenib.
Trazodone Trazodone The risk or severity of QTc prolongation can be increased when Trazodone is combined with Vemurafenib.
Phenobarbital Phenobarbital The metabolism of Phenobarbital can be increased when combined with Vemurafenib.
Methotrexate Injection Methotrexate Injection The risk or severity of adverse effects can be increased when Vemurafenib is combined with Methotrexate.
Primidone Primidone The metabolism of Primidone can be increased when combined with Vemurafenib.
Methsuximide Methsuximide The risk or severity of QTc prolongation can be increased when Methsuximide is combined with Vemurafenib.
Chlorpromazine Chlorpromazine The risk or severity of QTc prolongation can be increased when Vemurafenib is combined with Chlorpromazine.
Diazepam Diazepam The metabolism of Diazepam can be decreased when combined with Vemurafenib.
Lorazepam Lorazepam The metabolism of Lorazepam can be decreased when combined with Vemurafenib.
Carmustine Carmustine The serum concentration of Carmustine can be increased when it is combined with Vemurafenib.
Amantadine Amantadine The risk or severity of QTc prolongation can be increased when Amantadine is combined with Vemurafenib.
Codeine Codeine The metabolism of Codeine can be decreased when combined with Vemurafenib.
Bromocriptine Bromocriptine The metabolism of Bromocriptine can be decreased when combined with Vemurafenib.
Tranylcypromine Tranylcypromine The metabolism of Vemurafenib can be decreased when combined with Tranylcypromine.
Phenelzine Phenelzine The metabolism of Vemurafenib can be decreased when combined with Phenelzine.
Tetracycline Tetracycline The metabolism of Vemurafenib can be decreased when combined with Tetracycline.
Prochlorperazine Prochlorperazine The risk or severity of QTc prolongation can be increased when Vemurafenib is combined with Prochlorperazine.
Thioridazine Thioridazine The risk or severity of QTc prolongation can be increased when Vemurafenib is combined with Thioridazine.
Trifluoperazine Trifluoperazine The serum concentration of Trifluoperazine can be increased when it is combined with Vemurafenib.
Dapsone Dapsone The risk or severity of QTc prolongation can be increased when Vemurafenib is combined with Dapsone.
Sulfadiazine Sulfadiazine The metabolism of Sulfadiazine can be decreased when combined with Vemurafenib.
Oxycodone Oxycodone The metabolism of Oxycodone can be decreased when combined with Vemurafenib.
Methadone Methadone The metabolism of Vemurafenib can be increased when combined with Methadone.
Oxybutynin Oxybutynin The metabolism of Vemurafenib can be decreased when combined with Oxybutynin.
Benztropine Benztropine The risk or severity of QTc prolongation can be increased when Benzatropine is combined with Vemurafenib.
Colestipol Colestipol Colestipol can cause a decrease in the absorption of Vemurafenib resulting in a reduced serum concentration and potentially a decrease in efficacy.
Maprotiline Maprotiline The serum concentration of Maprotiline can be increased when it is combined with Vemurafenib.
Ibuprofen Ibuprofen The metabolism of Ibuprofen can be decreased when combined with Vemurafenib.
Orphenadrine Orphenadrine The risk or severity of QTc prolongation can be increased when Orphenadrine is combined with Vemurafenib.
Perphenazine Perphenazine The serum concentration of Perphenazine can be increased when it is combined with Vemurafenib.
Azathioprine Azathioprine The serum concentration of Azathioprine can be increased when it is combined with Vemurafenib.
Phentermine Phentermine The metabolism of Phentermine can be decreased when combined with Vemurafenib.
Amoxapine Amoxapine The risk or severity of QTc prolongation can be increased when Vemurafenib is combined with Amoxapine.
Sulfasalazine Sulfasalazine Sulfasalazine may decrease the excretion rate of Vemurafenib which could result in a higher serum level.
Hydrocortisone Hydrocortisone The metabolism of Vemurafenib can be increased when combined with Hydrocortisone.
Doxorubicin Doxorubicin The serum concentration of Doxorubicin can be increased when it is combined with Vemurafenib.
Dactinomycin Dactinomycin The serum concentration of Dactinomycin can be increased when it is combined with Vemurafenib.
Carbamazepine Carbamazepine The metabolism of Vemurafenib can be increased when combined with Carbamazepine.
Clonidine Clonidine The serum concentration of Clonidine can be increased when it is combined with Vemurafenib.
Prazosin Prazosin Vemurafenib may decrease the excretion rate of Prazosin which could result in a higher serum level.
Hydralazine Hydralazine The metabolism of Vemurafenib can be decreased when combined with Hydralazine.
Cimetidine Cimetidine The metabolism of Vemurafenib can be decreased when combined with Cimetidine.
Warfarin Warfarin The serum concentration of Warfarin can be increased when it is combined with Vemurafenib.
Clonazepam Clonazepam The metabolism of Clonazepam can be increased when combined with Vemurafenib.
Loperamide Loperamide The serum concentration of Loperamide can be increased when it is combined with Vemurafenib.
Promethazine Promethazine The risk or severity of QTc prolongation can be increased when Promethazine is combined with Vemurafenib.
Daunorubicin Daunorubicin The metabolism of Vemurafenib can be decreased when combined with Daunorubicin.
Nitrofurantoin Nitrofurantoin Vemurafenib may decrease the excretion rate of Nitrofurantoin which could result in a higher serum level.
Griseofulvin Griseofulvin The metabolism of Vemurafenib can be increased when combined with Griseofulvin.
Digoxin Digoxin The serum concentration of Digoxin can be increased when it is combined with Vemurafenib.
Loxapine Loxapine The serum concentration of Vemurafenib can be increased when it is combined with Loxapine.
Chloroquine Chloroquine The risk or severity of QTc prolongation can be increased when Vemurafenib is combined with Chloroquine.
Quinine Quinine The risk or severity of QTc prolongation can be increased when Vemurafenib is combined with Quinine.
Ethosuximide Ethosuximide The risk or severity of QTc prolongation can be increased when Vemurafenib is combined with Ethosuximide.
Calcitriol Calcitriol The metabolism of Vemurafenib can be increased when combined with Calcitriol.
Triamterene Triamterene The serum concentration of Triamterene can be increased when it is combined with Vemurafenib.
Sulfinpyrazone Sulfinpyrazone The metabolism of Vemurafenib can be increased when combined with Sulfinpyrazone.
Isosorbide Isosorbide The metabolism of Isosorbide can be increased when combined with Vemurafenib.
Clindamycin Injection Clindamycin Injection The metabolism of Clindamycin can be increased when combined with Vemurafenib.
Secobarbital Secobarbital The metabolism of Vemurafenib can be increased when combined with Secobarbital.
Desipramine Desipramine The risk or severity of QTc prolongation can be increased when Desipramine is combined with Vemurafenib.
Amitriptyline Amitriptyline The serum concentration of Amitriptyline can be increased when it is combined with Vemurafenib.
Imipramine Imipramine The serum concentration of Imipramine can be increased when it is combined with Vemurafenib.
Probenecid Probenecid The metabolism of Vemurafenib can be increased when combined with Probenecid.
Quinidine Quinidine The risk or severity of QTc prolongation can be increased when Vemurafenib is combined with Quinidine.
Procainamide Procainamide The metabolism of Procainamide can be decreased when combined with Vemurafenib.
Isoniazid Isoniazid The metabolism of Vemurafenib can be decreased when combined with Isoniazid.
Rifampin Rifampin The metabolism of Vemurafenib can be increased when combined with Rifampicin.
Disopyramide Disopyramide The serum concentration of Disopyramide can be increased when it is combined with Vemurafenib.
Valproic Acid Valproic Acid The metabolism of Vemurafenib can be decreased when combined with Valproic acid.
Tamoxifen Tamoxifen The serum concentration of Tamoxifen can be increased when it is combined with Vemurafenib.
Levothyroxine Levothyroxine The therapeutic efficacy of Levothyroxine can be decreased when used in combination with Vemurafenib.
Liothyronine Liothyronine The therapeutic efficacy of Liothyronine can be decreased when used in combination with Vemurafenib.
Methimazole Methimazole The therapeutic efficacy of Methimazole can be decreased when used in combination with Vemurafenib.
Propylthiouracil Propylthiouracil The therapeutic efficacy of Propylthiouracil can be decreased when used in combination with Vemurafenib.
Chlorpropamide Chlorpropamide The metabolism of Chlorpropamide can be decreased when combined with Vemurafenib.
Tolbutamide Tolbutamide The metabolism of Tolbutamide can be decreased when combined with Vemurafenib.
Tolazamide Tolazamide The metabolism of Tolazamide can be decreased when combined with Vemurafenib.
Dextromethorphan Dextromethorphan The metabolism of Dextromethorphan can be decreased when combined with Vemurafenib.
Cyclobenzaprine Cyclobenzaprine The serum concentration of Cyclobenzaprine can be increased when it is combined with Vemurafenib.
Niacin Niacin The metabolism of Vemurafenib can be decreased when combined with Niacin.
Doxylamine Doxylamine The risk or severity of QTc prolongation can be increased when Doxylamine is combined with Vemurafenib.
Cyproheptadine Cyproheptadine The risk or severity of QTc prolongation can be increased when Cyproheptadine is combined with Vemurafenib.
Clemastine Clemastine The risk or severity of QTc prolongation can be increased when Clemastine is combined with Vemurafenib.
Chlorpheniramine Chlorpheniramine The risk or severity of QTc prolongation can be increased when Chlorpheniramine is combined with Vemurafenib.
Brompheniramine Brompheniramine The risk or severity of QTc prolongation can be increased when Dexbrompheniramine is combined with Vemurafenib.
Meclizine Meclizine The metabolism of Meclizine can be decreased when combined with Vemurafenib.
Hydrochlorothiazide Hydrochlorothiazide The risk or severity of QTc prolongation can be increased when Hydrochlorothiazide is combined with Vemurafenib.
Chlorzoxazone Chlorzoxazone The serum concentration of Chlorzoxazone can be increased when it is combined with Vemurafenib.
Folic Acid Folic Acid Vemurafenib may decrease the excretion rate of Folic acid which could result in a higher serum level.
Danazol Danazol The metabolism of Vemurafenib can be decreased when combined with Danazol.
Disulfiram Disulfiram The risk or severity of QTc prolongation can be increased when Disulfiram is combined with Vemurafenib.
Propranolol (Cardiovascular) Propranolol (Cardiovascular) The serum concentration of Propranolol can be increased when it is combined with Vemurafenib.
Nortriptyline Nortriptyline The risk or severity of QTc prolongation can be increased when Vemurafenib is combined with Nortriptyline.
Amphotericin B Injection Amphotericin B Injection The metabolism of Vemurafenib can be decreased when combined with Amphotericin B.
Nadolol Nadolol The metabolism of Nadolol can be decreased when combined with Vemurafenib.
Cholestyramine Resin Cholestyramine Resin Cholestyramine can cause a decrease in the absorption of Vemurafenib resulting in a reduced serum concentration and potentially a decrease in efficacy.
Allopurinol Allopurinol Vemurafenib may decrease the excretion rate of Allopurinol which could result in a higher serum level.
Oxytocin Injection Oxytocin Injection The risk or severity of QTc prolongation can be increased when Oxytocin is combined with Vemurafenib.
Clomiphene Clomiphene The serum concentration of Clomifene can be increased when it is combined with Vemurafenib.
Papaverine Papaverine The risk or severity of QTc prolongation can be increased when Papaverine is combined with Vemurafenib.
Fluorouracil Injection Fluorouracil Injection The serum concentration of Fluorouracil can be increased when it is combined with Vemurafenib.
Colchicine Colchicine The serum concentration of Colchicine can be increased when it is combined with Vemurafenib.
Cephalexin Cephalexin The metabolism of Cephalexin can be decreased when combined with Vemurafenib.
Dacarbazine Dacarbazine The serum concentration of Dacarbazine can be increased when it is combined with Vemurafenib.
Acetazolamide Acetazolamide The metabolism of Vemurafenib can be decreased when combined with Acetazolamide.
Calcitonin Salmon Injection Calcitonin Salmon Injection The therapeutic efficacy of Salmon calcitonin can be decreased when used in combination with Vemurafenib.
Ketoconazole Ketoconazole The risk or severity of QTc prolongation can be increased when Ketoconazole is combined with Vemurafenib.
Thiotepa Injection Thiotepa Injection The metabolism of Thiotepa can be increased when combined with Vemurafenib.
Vincristine Injection Vincristine Injection The serum concentration of Vincristine can be increased when it is combined with Vemurafenib.
Vinblastine Vinblastine The serum concentration of Vinblastine can be increased when it is combined with Vemurafenib.
Metoprolol Metoprolol The metabolism of Metoprolol can be decreased when combined with Vemurafenib.
Hydroxyzine Hydroxyzine The risk or severity of QTc prolongation can be increased when Hydroxyzine is combined with Vemurafenib.
Thiothixene Thiothixene The serum concentration of Thiothixene can be increased when it is combined with Vemurafenib.
Aspirin Aspirin The metabolism of Acetylsalicylic acid can be decreased when combined with Vemurafenib.
Hyoscyamine Hyoscyamine The risk or severity of QTc prolongation can be increased when Hyoscyamine is combined with Vemurafenib.
Trimethoprim Trimethoprim The metabolism of Trimethoprim can be decreased when combined with Vemurafenib.
Diltiazem Diltiazem The metabolism of Diltiazem can be decreased when combined with Vemurafenib.
Nifedipine Nifedipine The serum concentration of Nifedipine can be increased when it is combined with Vemurafenib.
Timolol Timolol The risk or severity of QTc prolongation can be increased when Vemurafenib is combined with Timolol.
Verapamil Verapamil The serum concentration of Vemurafenib can be increased when it is combined with Verapamil.
Atenolol Atenolol The metabolism of Atenolol can be decreased when combined with Vemurafenib.
Pindolol Pindolol The metabolism of Pindolol can be decreased when combined with Vemurafenib.
Piroxicam Piroxicam The metabolism of Piroxicam can be decreased when combined with Vemurafenib.
Etoposide Etoposide The serum concentration of Etoposide can be increased when it is combined with Vemurafenib.
Glyburide Glyburide The metabolism of Glyburide can be decreased when combined with Vemurafenib.
Glipizide Glipizide The metabolism of Glipizide can be decreased when combined with Vemurafenib.
Indapamide Indapamide The risk or severity of QTc prolongation can be increased when Indapamide is combined with Vemurafenib.
Dicloxacillin Dicloxacillin The metabolism of Vemurafenib can be increased when combined with Dicloxacillin.
Nafcillin Injection Nafcillin Injection The metabolism of Vemurafenib can be increased when combined with Nafcillin.
Pentoxifylline Pentoxifylline The serum concentration of Pentoxifylline can be increased when it is combined with Vemurafenib.
Pentamidine Injection Pentamidine Injection The risk or severity of QTc prolongation can be increased when Pentamidine is combined with Vemurafenib.
Labetalol Labetalol The metabolism of Labetalol can be decreased when combined with Vemurafenib.
Leuprolide Injection Leuprolide Injection The risk or severity of QTc prolongation can be increased when Leuprolide is combined with Vemurafenib.
Guanabenz Guanabenz The serum concentration of Guanabenz can be increased when it is combined with Vemurafenib.
Ketoprofen Ketoprofen The risk or severity of adverse effects can be increased when Ketoprofen is combined with Vemurafenib.
Pimozide Pimozide The risk or severity of QTc prolongation can be increased when Vemurafenib is combined with Pimozide.
Flurbiprofen Flurbiprofen The metabolism of Flurbiprofen can be decreased when combined with Vemurafenib.
Amiodarone Amiodarone The metabolism of Vemurafenib can be decreased when combined with Amiodarone.
Buspirone Buspirone The metabolism of Buspirone can be decreased when combined with Vemurafenib.
Lovastatin Lovastatin The metabolism of Lovastatin can be decreased when combined with Vemurafenib.
Ciprofloxacin Ciprofloxacin The metabolism of Vemurafenib can be decreased when combined with Ciprofloxacin.
Diclofenac Diclofenac The serum concentration of Diclofenac can be increased when it is combined with Vemurafenib.
Fluoxetine Fluoxetine The serum concentration of Fluoxetine can be increased when it is combined with Vemurafenib.
Nimodipine Nimodipine The risk or severity of QTc prolongation can be increased when Nimodipine is combined with Vemurafenib.
Clozapine Clozapine The serum concentration of Clozapine can be increased when it is combined with Vemurafenib.
Idarubicin Idarubicin The metabolism of Idarubicin can be decreased when combined with Vemurafenib.
Ofloxacin Ofloxacin The risk or severity of QTc prolongation can be increased when Ofloxacin is combined with Vemurafenib.
Clarithromycin Clarithromycin The risk or severity of QTc prolongation can be increased when Vemurafenib is combined with Clarithromycin.
Etodolac Etodolac The metabolism of Etodolac can be decreased when combined with Vemurafenib.
Felodipine Felodipine The risk or severity of QTc prolongation can be increased when Vemurafenib is combined with Felodipine.
Nabumetone Nabumetone The serum concentration of Nabumetone can be increased when it is combined with Vemurafenib.
Pravastatin Pravastatin The serum concentration of Pravastatin can be increased when it is combined with Vemurafenib.
Simvastatin Simvastatin The serum concentration of Simvastatin can be increased when it is combined with Vemurafenib.
Epoetin Alfa, Injection Epoetin Alfa, Injection The risk or severity of Thrombosis can be increased when Erythropoietin is combined with Vemurafenib.
Amlodipine Amlodipine The metabolism of Amlodipine can be increased when combined with Vemurafenib.
Teniposide Injection Teniposide Injection The metabolism of Teniposide can be decreased when combined with Vemurafenib.
Itraconazole Itraconazole The risk or severity of QTc prolongation can be increased when Itraconazole is combined with Vemurafenib.
Atovaquone Atovaquone The risk or severity of QTc prolongation can be increased when Vemurafenib is combined with Atovaquone.
Rifabutin Rifabutin The metabolism of Vemurafenib can be increased when combined with Rifabutin.
Sotalol Sotalol The metabolism of Sotalol can be decreased when combined with Vemurafenib.
Bisoprolol Bisoprolol The serum concentration of Bisoprolol can be increased when it is combined with Vemurafenib.
Zolpidem Zolpidem The serum concentration of Zolpidem can be increased when it is combined with Vemurafenib.
Doxazosin Doxazosin The metabolism of Doxazosin can be decreased when combined with Vemurafenib.
Isradipine Isradipine The risk or severity of QTc prolongation can be increased when Isradipine is combined with Vemurafenib.
Omeprazole Omeprazole The metabolism of Vemurafenib can be increased when combined with Omeprazole.
Cisapride Cisapride The risk or severity of QTc prolongation can be increased when Cisapride is combined with Vemurafenib.
Fluvastatin Fluvastatin The metabolism of Fluvastatin can be decreased when combined with Vemurafenib.
Venlafaxine Venlafaxine The risk or severity of QTc prolongation can be increased when Venlafaxine is combined with Vemurafenib.
Famciclovir Famciclovir The metabolism of Famciclovir can be decreased when combined with Vemurafenib.
Fluvoxamine Fluvoxamine The serum concentration of Fluvoxamine can be increased when it is combined with Vemurafenib.
Nefazodone Nefazodone The metabolism of Nefazodone can be decreased when combined with Vemurafenib.
Lamotrigine Lamotrigine The risk or severity of QTc prolongation can be increased when Lamotrigine is combined with Vemurafenib.
Losartan Losartan The risk or severity of QTc prolongation can be increased when Vemurafenib is combined with Losartan.
Tramadol Tramadol The metabolism of Tramadol can be decreased when combined with Vemurafenib.
Vinorelbine Injection Vinorelbine Injection The metabolism of Vinorelbine can be increased when combined with Vemurafenib.
Moexipril Moexipril The risk or severity of QTc prolongation can be increased when Moexipril is combined with Vemurafenib.
Lansoprazole Lansoprazole The metabolism of Vemurafenib can be increased when combined with Lansoprazole.
Ifosfamide Injection Ifosfamide Injection The metabolism of Ifosfamide can be increased when combined with Vemurafenib.
Nicardipine Nicardipine The risk or severity of QTc prolongation can be increased when Vemurafenib is combined with Nicardipine.
Bupropion Bupropion The metabolism of Bupropion can be increased when combined with Vemurafenib.
Ticlopidine Ticlopidine The metabolism of Ticlopidine can be decreased when combined with Vemurafenib.
Saquinavir Saquinavir The serum concentration of Saquinavir can be increased when it is combined with Vemurafenib.
Metformin Metformin The therapeutic efficacy of Metformin can be increased when used in combination with Vemurafenib.
Lamivudine Lamivudine Vemurafenib may decrease the excretion rate of Lamivudine which could result in a higher serum level.
Riluzole Riluzole The serum concentration of Riluzole can be increased when it is combined with Vemurafenib.
Acarbose Acarbose The therapeutic efficacy of Acarbose can be increased when used in combination with Vemurafenib.
Glimepiride Glimepiride The metabolism of Glimepiride can be decreased when combined with Vemurafenib.
Anastrozole Anastrozole The metabolism of Anastrozole can be decreased when combined with Vemurafenib.
Gemcitabine Injection Gemcitabine Injection The serum concentration of Gemcitabine can be increased when it is combined with Vemurafenib.
Ritonavir Ritonavir The risk or severity of QTc prolongation can be increased when Ritonavir is combined with Vemurafenib.
Docetaxel Injection Docetaxel Injection The metabolism of Docetaxel can be increased when combined with Vemurafenib.
Clomipramine Clomipramine The serum concentration of Clomipramine can be increased when it is combined with Vemurafenib.
Zafirlukast Zafirlukast The metabolism of Zafirlukast can be decreased when combined with Vemurafenib.
Mirtazapine Mirtazapine The serum concentration of Mirtazapine can be increased when it is combined with Vemurafenib.
Topiramate Topiramate The metabolism of Vemurafenib can be increased when combined with Topiramate.
Zileuton Zileuton The serum concentration of Zileuton can be increased when it is combined with Vemurafenib.
Valsartan Valsartan The metabolism of Valsartan can be decreased when combined with Vemurafenib.
Insulin Lispro Injection Insulin Lispro Injection The therapeutic efficacy of Insulin lispro can be increased when used in combination with Vemurafenib.
Donepezil Donepezil Vemurafenib may decrease the excretion rate of Donepezil which could result in a higher serum level.
Nelfinavir Nelfinavir The risk or severity of QTc prolongation can be increased when Nelfinavir is combined with Vemurafenib.
Fexofenadine Fexofenadine The serum concentration of Fexofenadine can be increased when it is combined with Vemurafenib.
Azithromycin Azithromycin The risk or severity of QTc prolongation can be increased when Vemurafenib is combined with Azithromycin.
Carvedilol Carvedilol The serum concentration of Carvedilol can be increased when it is combined with Vemurafenib.
Flutamide Flutamide The serum concentration of Flutamide can be increased when it is combined with Vemurafenib.
Selegiline Selegiline The serum concentration of Selegiline can be increased when it is combined with Vemurafenib.
Bicalutamide Bicalutamide The metabolism of Vemurafenib can be decreased when combined with Bicalutamide.
Sertraline Sertraline The metabolism of Sertraline can be decreased when combined with Vemurafenib.
Propafenone Propafenone The serum concentration of Propafenone can be increased when it is combined with Vemurafenib.
Raloxifene Raloxifene The metabolism of Raloxifene can be decreased when combined with Vemurafenib.
Irbesartan Irbesartan The metabolism of Irbesartan can be decreased when combined with Vemurafenib.
Tamsulosin Tamsulosin The metabolism of Tamsulosin can be decreased when combined with Vemurafenib.
Ropinirole Ropinirole The serum concentration of Ropinirole can be increased when it is combined with Vemurafenib.
Quetiapine Quetiapine The risk or severity of QTc prolongation can be increased when Vemurafenib is combined with Quetiapine.
Cetirizine Cetirizine The risk or severity of QTc prolongation can be increased when Cetirizine is combined with Vemurafenib.
Paroxetine Paroxetine The serum concentration of Paroxetine can be increased when it is combined with Vemurafenib.
Citalopram Citalopram The metabolism of Citalopram can be decreased when combined with Vemurafenib.
Capecitabine Capecitabine The metabolism of Capecitabine can be decreased when combined with Vemurafenib.
Efavirenz Efavirenz The serum concentration of Vemurafenib can be increased when it is combined with Efavirenz.
Sildenafil Sildenafil The serum concentration of Sildenafil can be increased when it is combined with Vemurafenib.
Pioglitazone Pioglitazone The metabolism of Pioglitazone can be decreased when combined with Vemurafenib.
Celecoxib Celecoxib Vemurafenib may decrease the excretion rate of Celecoxib which could result in a higher serum level.
Rosiglitazone Rosiglitazone The metabolism of Rosiglitazone can be decreased when combined with Vemurafenib.
Tolterodine Tolterodine The risk or severity of QTc prolongation can be increased when Tolterodine is combined with Vemurafenib.
Thalidomide Thalidomide The metabolism of Thalidomide can be decreased when combined with Vemurafenib.
Colesevelam Colesevelam Colesevelam can cause a decrease in the absorption of Vemurafenib resulting in a reduced serum concentration and potentially a decrease in efficacy.
Nateglinide Nateglinide The metabolism of Nateglinide can be decreased when combined with Vemurafenib.
Galantamine Galantamine The risk or severity of QTc prolongation can be increased when Galantamine is combined with Vemurafenib.
Rabeprazole Rabeprazole The metabolism of Vemurafenib can be decreased when combined with Rabeprazole.
Terbinafine Terbinafine The serum concentration of Terbinafine can be increased when it is combined with Vemurafenib.

Content provided by: AHFS® Patient Medication Information™. © Copyright, 2021. The American Society of Health-System Pharmacists

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