Vilazodone

Vilazodone is used to treat depression. Vilazodone is in a class of medications called serotonin modulators. It works by increasing the amount of serotonin, a natural substance in the brain that helps maintain mental balance.

Vilazodone comes as a tablet to take by mouth. It is usually taken with food once a day. Take vilazodone at around the same time every day. Follow the directions on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand. Take vilazodone exactly as directed. Do not take more or less of it or take it more often than prescribed by your doctor.

Your doctor will probably start you on a low dose of vilazodone and gradually increase your dose, not more than once every 7 days.

Vilazodone controls depression but does not cure it. It may take several weeks before you feel the full benefit of vilazodone. Continue to take vilazodone even if you feel well. Do not stop taking vilazodone without talking to your doctor. Your doctor will probably decrease your dose gradually. If you suddenly stop taking vilazodone, you may experience withdrawal symptoms such as dizziness; nausea; headache; confusion; irritability; agitation; difficulty falling asleep or staying asleep; anxiety; extreme tiredness; seizures; pain, burning, or tingling in the hands or feet; frenzied or abnormally excited mood; or sweating. Tell your doctor if you experience any of these symptoms while you are decreasing your dose of vilazodone or soon after you stop taking vilazodone.

This medication may be prescribed for other uses; ask your doctor or pharmacist for more information.

Before taking vilazodone,

• tell your doctor and pharmacist if you are allergic to vilazodone, any other medications, or any of the ingredients in vilazodone tablets. Ask your pharmacist or check the Medication Guide for a list of the ingredients.

• tell your doctor if you are taking a monoamine oxidase (MAO) inhibitor, such as isocarboxazid (Marplan), linezolid, methylene blue, phenelzine (Nardil), selegiline (Eldepryl, Emsam, Zelapar), and tranylcypromine (Parnate), or if you have stopped taking one of these medications within the past 14 days. Your doctor will probably tell you that you should not take vilazodone. If you stop taking vilazodone, your doctor will tell you that you should wait at least 14 days before you start to take an MAO inhibitor.

• tell your doctor and pharmacist what other prescription and nonprescription medications, and vitamins you are taking or plan to take. Be sure to mention any of the following: amphetamines such as amphetamine (in Adderall, in Mydayis), dextroamphetamine (Dexedrine, in Adderall), and methamphetamine (Desoxyn); anticoagulants ('blood thinners') such as warfarin (Coumadin, Jantoven); aspirin and other nonsteroidal anti-inflammatory drugs (NSAIDs) such as ibuprofen (Advil, Motrin) and naproxen (Aleve, Naprosyn); buspirone; carbamazepine (Carbatrol, Equetro, Tegretol, others); clarithromycin; digoxin (Lanoxin); diuretics ('water pills'); fentanyl (Actiq, Duragesic, Fentora, Subsys); itraconazole (Sporanox); lithium (Lithobid); medications for anxiety, mental illness, or nausea; medications for migraine such as almotriptan, eletriptan (Relpax), frovatriptan (Frova), naratriptan (Amerge), rizatriptan (Maxalt), sumatriptan (Imitrex), and zolmitriptan (Zomig); phenytoin (Dilantin, Phenytek); rifampin (Rifadin, Rimactane); sedatives; selective serotonin reuptake inhibitors (SSRIs) such as citalopram (Celexa), escitalopram (Lexapro), fluoxetine (Prozac, Sarafem), fluvoxamine (Luvox), paroxetine (Paxil, Pexeva), and sertraline (Zoloft); selective serotonin and norepinephrine reuptake inhibitors (SNRIs) such as desvenlafaxine (Pristiq), duloxetine (Cymbalta), and venlafaxine (Effexor); sleeping pills; tramadol (Conzip, Qdola, Ultram, in Ultracet); tranquilizers; tricyclic antidepressants such as amitriptyline, amoxapine (Asendin), clomipramine (Anafranil), desipramine (Norpramin), doxepin (Sinequan), imipramine (Tofranil), nortriptyline (Pamelor), protriptyline, and trimipramine; and voriconazole (Vfend). Your doctor may need to change the doses of your medications or monitor you carefully for side effects. Many other medications may also interact with vilazodone, so be sure to tell your doctor about all the medications you are taking, even those that do not appear on this list.

• tell your doctor what herbal products and nutritional supplements you are taking, especially St. John's wort and tryptophan.

• tell your doctor if you have a low level of sodium in your blood or glaucoma (increased pressure in the eye that may cause loss of sight), and if you drink or have ever drunk large amounts of alcohol, Also tell your doctor if you have or have ever had bleeding problems, seizures, or liver disease.

• tell your doctor if you are pregnant, especially if you are in the last few months of your pregnancy, or if you plan to become pregnant or are breast-feeding. If you become pregnant while taking vilazodone, call your doctor. Vilazodone may cause problems in newborns following delivery if it is taken during the last months of pregnancy.

• if you are having surgery, including dental surgery, tell the doctor or dentist that you are taking vilazodone.

• you should know that vilazodone may make you drowsy and affect your judgment and thinking. Do not drive a car or operate machinery until you know how this medication affects you.

• ask your doctor about the safe use of alcoholic beverages while you are taking vilazodone. Alcohol can make the side effects from vilazodone worse.

• you should know that vilazodone may cause angle-closure glaucoma (a condition where the fluid is suddenly blocked and unable to flow out of the eye causing a quick, severe increase in eye pressure which may lead to a loss of vision). Talk to your doctor about having an eye examination before you start taking this medication. If you have nausea, eye pain, changes in vision, such as seeing colored rings around lights, and swelling or redness in or around the eye, call your doctor or get emergency medical treatment right away.

Unless your doctor tells you otherwise, continue your normal diet.

Take the missed dose as soon as you remember it. However, if it is almost time for the next dose, skip the missed dose and continue your regular dosing schedule. Do not take a double dose to make up for a missed one.

• Vilazodone may cause side effects. Tell your doctor if any of these symptoms are severe or do not go away:

  • dry mouth

  • increased appetite

  • heartburn

  • gas

  • dizziness

  • pain, burning, or tingling in the hands or feet

  • uncontrollable shaking of a part of the body

  • unusual dreams

  • tiredness

  • joint pain

  • sexual problems in males; decreased sex drive, inability to get or keep an erection, or delayed or absent ejaculation

  • sexual problems in females; decreased sex drive, or delayed orgasm or unable to have an orgasm

• Some side effects can be serious. If you experience any of these symptoms or those listed in the IMPORTANT WARNING or SPECIAL PRECAUTIONS sections, call your doctor immediately:

  • rash

  • hives

  • swelling

  • difficulty breathing

  • loss of consciousness

  • seizures

  • fever, sweating, confusion, fast or irregular heartbeat, and severe muscle stiffness or twitching, agitation, hallucinations, loss of coordination, nausea, vomiting, or diarrhea

  • unusual bleeding or bruising

  • nosebleeds

  • small red or purple dots on the skin

  • hallucinations (seeing things or hearing voices that do not exist)

  • headache

  • difficulty concentrating

  • memory problems

  • weakness

  • problems with coordination

  • increased falls

  • fainting

• Vilazodone may cause other side effects. Call your doctor if you have any unusual problems while taking this medication.

• If you experience a serious side effect, you or your doctor may send a report to the Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting program online (http://www.fda.gov/Safety/MedWatch) or by phone (1-800-332-1088).

Keep this medication in the container it came in, tightly closed, and out of reach of children. Store it at room temperature and away from excess heat and moisture (not in the bathroom).

Unneeded medications should be disposed of in special ways to ensure that pets, children, and other people cannot consume them. However, you should not flush this medication down the toilet. Instead, the best way to dispose of your medication is through a medicine take-back program. Talk to your pharmacist or contact your local garbage/recycling department to learn about take-back programs in your community. See the FDA's Safe Disposal of Medicines website (http://goo.gl/c4Rm4p) for more information if you do not have access to a take-back program.

It is important to keep all medication out of sight and reach of children as many containers (such as weekly pill minders and those for eye drops, creams, patches, and inhalers) are not child-resistant and young children can open them easily. To protect young children from poisoning, always lock safety caps and immediately place the medication in a safe location – one that is up and away and out of their sight and reach. http://www.upandaway.org

In case of overdose, call the poison control helpline at 1-800-222-1222. Information is also available online at https://www.poisonhelp.org/help. If the victim has collapsed, had a seizure, has trouble breathing, or can't be awakened, immediately call emergency services at 911.

Symptoms of overdose may include the following:

• fever, sweating, confusion, fast or irregular heartbeat, and severe muscle stiffness or twitching, loss of coordination, nausea, vomiting, or diarrhea

• excessive tiredness

• hallucinations (seeing things or hearing voices that do not exist)

• lack of energy

• restlessness

• disorientation

Do not let anyone else take your medication. Ask your pharmacist any questions you have about refilling your prescription.

It is important for you to keep a written list of all of the prescription and nonprescription (over-the-counter) medicines you are taking, as well as any products such as vitamins, minerals, or other dietary supplements. You should bring this list with you each time you visit a doctor or if you are admitted to a hospital. It is also important information to carry with you in case of emergencies.

Drug	Interaction
Delavirdine	Delavirdine The metabolism of Vilazodone can be decreased when combined with Delavirdine.
Nevirapine	Nevirapine The metabolism of Nevirapine can be decreased when combined with Vilazodone.
Dolasetron	Dolasetron The metabolism of Vilazodone can be decreased when combined with Dolasetron.
Candesartan	Candesartan Vilazodone may decrease the antihypertensive activities of Candesartan.
Cilostazol	Cilostazol The metabolism of Cilostazol can be decreased when combined with Vilazodone.
Clopidogrel	Clopidogrel The metabolism of Vilazodone can be decreased when combined with Clopidogrel.
Diphenoxylate	Diphenoxylate The risk or severity of adverse effects can be increased when Diphenoxylate is combined with Vilazodone.
Fenofibrate	Fenofibrate The metabolism of Vilazodone can be decreased when combined with Fenofibrate.
Guanfacine	Guanfacine The risk or severity of adverse effects can be increased when Guanfacine is combined with Vilazodone.
Methylergonovine	Methylergonovine Methylergometrine may increase the vasoconstricting activities of Vilazodone.
Naratriptan	Naratriptan The risk or severity of adverse effects can be increased when Naratriptan is combined with Vilazodone.
Olsalazine	Olsalazine The risk or severity of hypertension can be increased when Olsalazine is combined with Vilazodone.
Paregoric	Paregoric The risk or severity of adverse effects can be increased when Morphine is combined with Vilazodone.
Penbutolol	Penbutolol The metabolism of Acebutolol can be decreased when combined with Vilazodone.
Pentazocine	Pentazocine The risk or severity of adverse effects can be increased when Pentazocine is combined with Vilazodone.
Ranitidine	Ranitidine The metabolism of Vilazodone can be decreased when combined with Ranitidine.
Reserpine	Reserpine The risk or severity of adverse effects can be increased when Reserpine is combined with Vilazodone.
Rizatriptan	Rizatriptan The risk or severity of adverse effects can be increased when Rizatriptan is combined with Vilazodone.
Sumatriptan	Sumatriptan The risk or severity of adverse effects can be increased when Sumatriptan is combined with Vilazodone.
Tizanidine	Tizanidine The risk or severity of adverse effects can be increased when Tizanidine is combined with Vilazodone.
Zolmitriptan	Zolmitriptan The risk or severity of vasospastic reactions can be increased when Zolmitriptan is combined with Vilazodone.
Fluconazole Injection	Fluconazole Injection The metabolism of Vilazodone can be decreased when combined with Fluconazole.
Hydromorphone Injection	Hydromorphone Injection The risk or severity of adverse effects can be increased when Hydromorphone is combined with Vilazodone.
Meperidine Injection	Meperidine Injection The metabolism of Meperidine can be decreased when combined with Vilazodone.
Metoclopramide Injection	Metoclopramide Injection The risk or severity of sedation can be increased when Vilazodone is combined with Metoclopramide.
Morphine Injection	Morphine Injection The risk or severity of adverse effects can be increased when Morphine is combined with Vilazodone.
Altretamine	Altretamine The metabolism of Vilazodone can be decreased when combined with Amphetamine.
Cyclosporine	Cyclosporine The metabolism of Cyclosporine can be decreased when combined with Vilazodone.
Ondansetron	Ondansetron The metabolism of Vilazodone can be decreased when combined with Ondansetron.
Granisetron	Granisetron The risk or severity of adverse effects can be increased when Granisetron is combined with Vilazodone.
Torsemide	Torsemide Vilazodone may decrease the antihypertensive activities of Torasemide.
Olanzapine	Olanzapine The metabolism of Vilazodone can be decreased when combined with Olanzapine.
Alosetron	Alosetron The risk or severity of adverse effects can be increased when Alosetron is combined with Vilazodone.
Entacapone	Entacapone The risk or severity of adverse effects can be increased when Entacapone is combined with Vilazodone.
Eprosartan	Eprosartan Vilazodone may decrease the antihypertensive activities of Eprosartan.
Hydroxychloroquine	Hydroxychloroquine The metabolism of Vilazodone can be decreased when combined with Hydroxychloroquine.
Meloxicam	Meloxicam The risk or severity of hypertension can be increased when Meloxicam is combined with Vilazodone.
Oxcarbazepine	Oxcarbazepine The risk or severity of adverse effects can be increased when Oxcarbazepine is combined with Vilazodone.
Pantoprazole	Pantoprazole The metabolism of Vilazodone can be decreased when combined with Pantoprazole.
Telmisartan	Telmisartan The metabolism of Telmisartan can be decreased when combined with Vilazodone.
Zaleplon	Zaleplon The risk or severity of adverse effects can be increased when Zaleplon is combined with Vilazodone.
Anakinra	Anakinra The metabolism of Vilazodone can be increased when combined with Anakinra.
Desloratadine	Desloratadine The risk or severity of adverse effects can be increased when Desloratadine is combined with Vilazodone.
Linezolid	Linezolid The risk or severity of serotonin syndrome can be increased when Linezolid is combined with Vilazodone.
Trimipramine	Trimipramine The metabolism of Vilazodone can be decreased when combined with Trimipramine.
Etanercept Injection	Etanercept Injection The metabolism of Vilazodone can be increased when combined with Etanercept.
Glycopyrrolate	Glycopyrrolate Vilazodone may increase the central nervous system depressant (CNS depressant) activities of Glycopyrronium.
Modafinil	Modafinil The metabolism of Vilazodone can be decreased when combined with Modafinil.
Perindopril	Perindopril Vilazodone may decrease the antihypertensive activities of Perindopril.
Choline Magnesium Trisalicylate	Choline Magnesium Trisalicylate The risk or severity of hypertension can be increased when Choline magnesium trisalicylate is combined with Vilazodone.
Dutasteride	Dutasteride The risk or severity of hypertension can be increased when Dutasteride is combined with Vilazodone.
Epinephrine Injection	Epinephrine Injection The risk or severity of hypertension can be increased when Epinephrine is combined with Vilazodone.
Eplerenone	Eplerenone Vilazodone may decrease the antihypertensive activities of Eplerenone.
Escitalopram	Escitalopram The risk or severity of serotonin syndrome can be increased when Escitalopram is combined with Vilazodone.
Olmesartan	Olmesartan Vilazodone may decrease the antihypertensive activities of Olmesartan.
Zonisamide	Zonisamide The risk or severity of adverse effects can be increased when Zonisamide is combined with Vilazodone.
Adalimumab Injection	Adalimumab Injection The metabolism of Vilazodone can be increased when combined with Adalimumab.
Aripiprazole	Aripiprazole The metabolism of Vilazodone can be decreased when combined with Aripiprazole.
Atomoxetine	Atomoxetine The metabolism of Atomoxetine can be decreased when combined with Vilazodone.
Dexmethylphenidate	Dexmethylphenidate The risk or severity of adverse effects can be increased when Vilazodone is combined with Dexmethylphenidate.
Atazanavir	Atazanavir The metabolism of Vilazodone can be decreased when combined with Atazanavir.
Almotriptan	Almotriptan The metabolism of Vilazodone can be decreased when combined with Almotriptan.
Eletriptan	Eletriptan The metabolism of Eletriptan can be decreased when combined with Vilazodone.
Mefloquine	Mefloquine The metabolism of Vilazodone can be decreased when combined with Mefloquine.
Aprepitant	Aprepitant The metabolism of Vilazodone can be decreased when combined with Aprepitant.
Memantine	Memantine The metabolism of Vilazodone can be decreased when combined with Memantine.
Tegaserod	Tegaserod The metabolism of Vilazodone can be decreased when combined with Tegaserod.
Tadalafil	Tadalafil Vilazodone may decrease the antihypertensive activities of Tadalafil.
Frovatriptan	Frovatriptan The risk or severity of adverse effects can be increased when Frovatriptan is combined with Vilazodone.
Progesterone	Progesterone The metabolism of Vilazodone can be decreased when combined with Progesterone.
Apomorphine Injection	Apomorphine Injection The risk or severity of adverse effects can be increased when Apomorphine is combined with Vilazodone.
Infliximab Injection	Infliximab Injection The metabolism of Vilazodone can be increased when combined with Infliximab.
Protriptyline	Protriptyline The metabolism of Vilazodone can be decreased when combined with Protriptyline.
Rifaximin	Rifaximin The metabolism of Vilazodone can be increased when combined with Rifaximin.
Duloxetine	Duloxetine The metabolism of Vilazodone can be decreased when combined with Duloxetine.
Trospium	Trospium Vilazodone may increase the central nervous system depressant (CNS depressant) activities of Trospium.
Bosentan	Bosentan Vilazodone may decrease the antihypertensive activities of Bosentan.
Cinacalcet	Cinacalcet The metabolism of Vilazodone can be decreased when combined with Cinacalcet.
Erlotinib	Erlotinib The metabolism of Erlotinib can be decreased when combined with Vilazodone.
Eszopiclone	Eszopiclone The risk or severity of CNS depression can be increased when Vilazodone is combined with Eszopiclone.
Solifenacin	Solifenacin The metabolism of Solifenacin can be decreased when combined with Vilazodone.
Voriconazole	Voriconazole The metabolism of Vilazodone can be decreased when combined with Voriconazole.
Dextroamphetamine	Dextroamphetamine The metabolism of Vilazodone can be decreased when combined with Amphetamine.
Peginterferon Alfa-2b (PEG-Intron)	Peginterferon Alfa-2b (PEG-Intron) The metabolism of Vilazodone can be decreased when combined with Peginterferon alfa-2b.
Sodium Oxybate	Sodium Oxybate Sodium oxybate may increase the central nervous system depressant (CNS depressant) activities of Vilazodone.
Isocarboxazid	Isocarboxazid The metabolism of Vilazodone can be decreased when combined with Isocarboxazid.
Ramelteon	Ramelteon The risk or severity of adverse effects can be increased when Ramelteon is combined with Vilazodone.
Darifenacin	Darifenacin The metabolism of Darifenacin can be decreased when combined with Vilazodone.
Fentanyl	Fentanyl The risk or severity of adverse effects can be increased when Fentanyl is combined with Vilazodone.
Pregabalin	Pregabalin The therapeutic efficacy of Vilazodone can be increased when used in combination with Pregabalin.
Phenylephrine	Phenylephrine The risk or severity of hypertension can be increased when Phenylephrine is combined with Vilazodone.
Tipranavir	Tipranavir The metabolism of Tipranavir can be decreased when combined with Vilazodone.
Felbamate	Felbamate The risk or severity of adverse effects can be increased when Felbamate is combined with Vilazodone.
Ranolazine	Ranolazine The serum concentration of Vilazodone can be increased when it is combined with Ranolazine.
Abatacept Injection	Abatacept Injection The metabolism of Vilazodone can be increased when combined with Abatacept.
Rasagiline	Rasagiline The metabolism of Vilazodone can be decreased when combined with Rasagiline.
Imatinib	Imatinib The metabolism of Imatinib can be decreased when combined with Vilazodone.
Gefitinib	Gefitinib The metabolism of Gefitinib can be decreased when combined with Vilazodone.
Albuterol	Albuterol The risk or severity of hypertension can be increased when Salbutamol is combined with Vilazodone.
Paliperidone	Paliperidone The metabolism of Vilazodone can be decreased when combined with Paliperidone.
Bortezomib	Bortezomib The metabolism of Bortezomib can be decreased when combined with Vilazodone.
Posaconazole	Posaconazole The metabolism of Vilazodone can be decreased when combined with Posaconazole.
Primaquine	Primaquine The metabolism of Vilazodone can be decreased when combined with Primaquine.
Aliskiren	Aliskiren Vilazodone may decrease the antihypertensive activities of Aliskiren.
Darunavir	Darunavir The metabolism of Darunavir can be decreased when combined with Vilazodone.
Dimenhydrinate	Dimenhydrinate The risk or severity of adverse effects can be increased when Dimenhydrinate is combined with Vilazodone.
Lisdexamfetamine	Lisdexamfetamine The metabolism of Vilazodone can be decreased when combined with Lisdexamfetamine.
Nabilone	Nabilone Nabilone may increase the central nervous system depressant (CNS depressant) activities of Vilazodone.
Sorafenib	Sorafenib The metabolism of Vilazodone can be decreased when combined with Sorafenib.
Dronabinol	Dronabinol Dronabinol may increase the central nervous system depressant (CNS depressant) activities of Vilazodone.
Lapatinib	Lapatinib The metabolism of Vilazodone can be decreased when combined with Lapatinib.
Levocetirizine	Levocetirizine The risk or severity of adverse effects can be increased when Levocetirizine is combined with Vilazodone.
Mexiletine	Mexiletine The metabolism of Mexiletine can be decreased when combined with Vilazodone.
Armodafinil	Armodafinil The metabolism of Vilazodone can be decreased when combined with Armodafinil.
Temsirolimus	Temsirolimus The metabolism of Vilazodone can be decreased when combined with Temsirolimus.
Nilotinib	Nilotinib The metabolism of Vilazodone can be decreased when combined with Nilotinib.
Chloramphenicol Injection	Chloramphenicol Injection The metabolism of Vilazodone can be decreased when combined with Chloramphenicol.
Desmopressin	Desmopressin The risk or severity of hypertension can be increased when Desmopressin is combined with Vilazodone.
OnabotulinumtoxinA Injection	OnabotulinumtoxinA Injection The risk or severity of adverse effects can be increased when Botulinum toxin type A is combined with Vilazodone.
RimabotulinumtoxinB Injection	RimabotulinumtoxinB Injection The risk or severity of adverse effects can be increased when Botulinum Toxin Type B is combined with Vilazodone.
Etravirine	Etravirine The metabolism of Vilazodone can be decreased when combined with Etravirine.
Desvenlafaxine	Desvenlafaxine The risk or severity of adverse effects can be increased when Vilazodone is combined with Desvenlafaxine.
Cevimeline	Cevimeline The metabolism of Cevimeline can be decreased when combined with Vilazodone.
Nebivolol	Nebivolol The metabolism of Nebivolol can be decreased when combined with Vilazodone.
Flecainide	Flecainide The metabolism of Flecainide can be decreased when combined with Vilazodone.
Certolizumab Injection	Certolizumab Injection The metabolism of Vilazodone can be increased when combined with Certolizumab pegol.
Praziquantel	Praziquantel The metabolism of Vilazodone can be decreased when combined with Praziquantel.
Mitotane	Mitotane The metabolism of Vilazodone can be increased when combined with Mitotane.
Rufinamide	Rufinamide The risk or severity of adverse effects can be increased when Rufinamide is combined with Vilazodone.
Midazolam	Midazolam The risk or severity of adverse effects can be increased when Midazolam is combined with Vilazodone.
Naltrexone Injection	Naltrexone Injection The risk or severity of serotonin syndrome can be increased when Naltrexone is combined with Vilazodone.
Milnacipran	Milnacipran The risk or severity of adverse effects can be increased when Milnacipran is combined with Vilazodone.
Dexlansoprazole	Dexlansoprazole The metabolism of Vilazodone can be decreased when combined with Dexlansoprazole.
Fesoterodine	Fesoterodine The metabolism of Fesoterodine can be decreased when combined with Vilazodone.
Betaxolol	Betaxolol The metabolism of Betaxolol can be decreased when combined with Vilazodone.
Iloperidone	Iloperidone The metabolism of Vilazodone can be decreased when combined with Iloperidone.
Lacosamide	Lacosamide The risk or severity of adverse effects can be increased when Lacosamide is combined with Vilazodone.
Everolimus	Everolimus The metabolism of Vilazodone can be decreased when combined with Everolimus.
Dronedarone	Dronedarone The metabolism of Dronedarone can be decreased when combined with Vilazodone.
AbobotulinumtoxinA Injection	AbobotulinumtoxinA Injection The risk or severity of adverse effects can be increased when Botulinum toxin type A is combined with Vilazodone.
Palonosetron Injection	Palonosetron Injection The metabolism of Vilazodone can be decreased when combined with Palonosetron.
Tapentadol	Tapentadol Tapentadol may increase the central nervous system depressant (CNS depressant) activities of Vilazodone.
Golimumab Injection	Golimumab Injection The metabolism of Vilazodone can be increased when combined with Golimumab.
Pazopanib	Pazopanib The metabolism of Pazopanib can be decreased when combined with Vilazodone.
Asenapine	Asenapine The risk or severity of adverse effects can be increased when Asenapine is combined with Vilazodone.
Vigabatrin	Vigabatrin The risk or severity of adverse effects can be increased when Vigabatrin is combined with Vilazodone.
Albendazole	Albendazole The metabolism of Vilazodone can be decreased when combined with Albendazole.
Oxymorphone	Oxymorphone The metabolism of Vilazodone can be decreased when combined with Oxymorphone.
Tocilizumab Injection	Tocilizumab Injection The metabolism of Vilazodone can be increased when combined with Tocilizumab.
IncobotulinumtoxinA Injection	IncobotulinumtoxinA Injection The risk or severity of adverse effects can be increased when Botulinum toxin type A is combined with Vilazodone.
Lurasidone	Lurasidone The risk or severity of adverse effects can be increased when Vilazodone is combined with Lurasidone.
Acetaminophen Injection	Acetaminophen Injection The metabolism of Vilazodone can be decreased when combined with Acetaminophen.
Terbutaline Injection	Terbutaline Injection The risk or severity of hypertension can be increased when Terbutaline is combined with Vilazodone.
Rilpivirine	Rilpivirine The metabolism of Vilazodone can be decreased when combined with Rilpivirine.
Cyclophosphamide Injection	Cyclophosphamide Injection The metabolism of Vilazodone can be decreased when combined with Cyclophosphamide.
Abiraterone	Abiraterone The metabolism of Vilazodone can be decreased when combined with Abiraterone.
Clobazam	Clobazam The metabolism of Vilazodone can be decreased when combined with Clobazam.
Vemurafenib	Vemurafenib The metabolism of Vilazodone can be decreased when combined with Vemurafenib.
Vismodegib	Vismodegib The metabolism of Vilazodone can be decreased when combined with Vismodegib.
Axitinib	Axitinib The metabolism of Vilazodone can be decreased when combined with Axitinib.
Cabergoline	Cabergoline Cabergoline may increase the vasoconstricting activities of Vilazodone.
Naloxone Injection	Naloxone Injection The metabolism of Vilazodone can be decreased when combined with Naloxone.
Ambrisentan	Ambrisentan Vilazodone may decrease the antihypertensive activities of Ambrisentan.
Ezogabine	Ezogabine The risk or severity of adverse effects can be increased when Tiagabine is combined with Vilazodone.
Enzalutamide	Enzalutamide The metabolism of Vilazodone can be increased when combined with Enzalutamide.
Mirabegron	Mirabegron The metabolism of Mirabegron can be decreased when combined with Vilazodone.
Alogliptin	Alogliptin The metabolism of Alogliptin can be decreased when combined with Vilazodone.
Ponatinib	Ponatinib The metabolism of Ponatinib can be decreased when combined with Vilazodone.
Pomalidomide	Pomalidomide The risk or severity of adverse effects can be increased when Vilazodone is combined with Pomalidomide.
Apixaban	Apixaban The metabolism of Vilazodone can be decreased when combined with Apixaban.
Dabrafenib	Dabrafenib The serum concentration of Vilazodone can be decreased when it is combined with Dabrafenib.
Ospemifene	Ospemifene The metabolism of Vilazodone can be decreased when combined with Ospemifene.
Levomilnacipran	Levomilnacipran The metabolism of Levomilnacipran can be decreased when combined with Vilazodone.
Vortioxetine	Vortioxetine The metabolism of Vortioxetine can be decreased when combined with Vilazodone.
Perampanel	Perampanel Perampanel may increase the central nervous system depressant (CNS depressant) activities of Vilazodone.
Ibrutinib	Ibrutinib The metabolism of Ibrutinib can be decreased when combined with Vilazodone.
Ketorolac Injection	Ketorolac Injection The risk or severity of hypertension can be increased when Ketorolac is combined with Vilazodone.
Dapagliflozin	Dapagliflozin The metabolism of Dapagliflozin can be decreased when combined with Vilazodone.
Apremilast	Apremilast The metabolism of Vilazodone can be increased when combined with Apremilast.
Droxidopa	Droxidopa Vilazodone may increase the hypertensive activities of Droxidopa.
Siltuximab Injection	Siltuximab Injection The metabolism of Vilazodone can be increased when combined with Siltuximab.
Eslicarbazepine	Eslicarbazepine The risk or severity of adverse effects can be increased when Vilazodone is combined with Eslicarbazepine.
Testosterone Injection	Testosterone Injection The metabolism of Vilazodone can be decreased when combined with Testosterone.
Oritavancin Injection	Oritavancin Injection The metabolism of Vilazodone can be decreased when combined with Oritavancin.
Hydrocodone	Hydrocodone Hydrocodone may increase the central nervous system depressant (CNS depressant) activities of Vilazodone.
Suvorexant	Suvorexant Vilazodone may increase the central nervous system depressant (CNS depressant) activities of Suvorexant.
Methamphetamine	Methamphetamine The metabolism of Vilazodone can be decreased when combined with Metamfetamine.
Tasimelteon	Tasimelteon The risk or severity of adverse effects can be increased when Vilazodone is combined with Tasimelteon.
Riociguat	Riociguat Vilazodone may decrease the antihypertensive activities of Riociguat.
Secukinumab Injection	Secukinumab Injection The metabolism of Vilazodone can be increased when combined with Secukinumab.
Risperidone Injection	Risperidone Injection The metabolism of Vilazodone can be decreased when combined with Risperidone.
Lenvatinib	Lenvatinib The metabolism of Vilazodone can be decreased when combined with Lenvatinib.
Naloxegol	Naloxegol The metabolism of Vilazodone can be decreased when combined with Naloxegol.
Panobinostat	Panobinostat The metabolism of Vilazodone can be decreased when combined with Panobinostat.
Haloperidol Injection	Haloperidol Injection The risk or severity of CNS depression can be increased when Haloperidol is combined with Vilazodone.
Macitentan	Macitentan Vilazodone may decrease the antihypertensive activities of Macitentan.
Flibanserin	Flibanserin The risk or severity of adverse effects can be increased when Flibanserin is combined with Vilazodone.
Rolapitant	Rolapitant The metabolism of Vilazodone can be decreased when combined with Rolapitant.
Brexpiprazole	Brexpiprazole The metabolism of Brexpiprazole can be decreased when combined with Vilazodone.
Ziprasidone Injection	Ziprasidone Injection The risk or severity of adverse effects can be increased when Ziprasidone is combined with Vilazodone.
Cariprazine	Cariprazine The metabolism of Vilazodone can be decreased when combined with Cariprazine.
Eluxadoline	Eluxadoline The risk or severity of serotonin syndrome can be increased when Vilazodone is combined with Eluxadoline.
Trabectedin Injection	Trabectedin Injection The metabolism of Trabectedin can be decreased when combined with Vilazodone.
Rifapentine	Rifapentine The metabolism of Vilazodone can be increased when combined with Rifapentine.
Dexamethasone Injection	Dexamethasone Injection The metabolism of Vilazodone can be increased when combined with Dexamethasone.
Brivaracetam Injection	Brivaracetam Injection The risk or severity of adverse effects can be increased when Brivaracetam is combined with Vilazodone.
Cobicistat	Cobicistat The metabolism of Vilazodone can be decreased when combined with Cobicistat.
Midodrine	Midodrine The risk or severity of hypertension can be increased when Midodrine is combined with Vilazodone.
Selexipag	Selexipag Vilazodone may decrease the antihypertensive activities of Selexipag.
Pimavanserin	Pimavanserin The risk or severity of adverse effects can be increased when Pimavanserin is combined with Vilazodone.
Diphenhydramine Injection	Diphenhydramine Injection The metabolism of Vilazodone can be decreased when combined with Diphenhydramine.
Furosemide Injection	Furosemide Injection Vilazodone may decrease the antihypertensive activities of Furosemide.
Rucaparib	Rucaparib The metabolism of Rucaparib can be decreased when combined with Vilazodone.
Ribociclib	Ribociclib The metabolism of Vilazodone can be decreased when combined with Ribociclib.
Doxepin (Insomnia)	Doxepin (Insomnia) The metabolism of Vilazodone can be decreased when combined with Doxepin.
Deutetrabenazine	Deutetrabenazine The metabolism of Deutetrabenazine can be decreased when combined with Vilazodone.
Valbenazine	Valbenazine The metabolism of Valbenazine can be decreased when combined with Vilazodone.
Safinamide	Safinamide The metabolism of Vilazodone can be decreased when combined with Safinamide.
Midostaurin	Midostaurin The metabolism of Vilazodone can be decreased when combined with Midostaurin.
Enasidenib	Enasidenib The metabolism of Vilazodone can be decreased when combined with Enasidenib.
Letermovir	Letermovir The metabolism of Letermovir can be decreased when combined with Vilazodone.
Tetrabenazine	Tetrabenazine The metabolism of Tetrabenazine can be decreased when combined with Vilazodone.
Buprenorphine Injection	Buprenorphine Injection Vilazodone may increase the central nervous system depressant (CNS depressant) activities of Buprenorphine.
Apalutamide	Apalutamide The metabolism of Vilazodone can be increased when combined with Apalutamide.
Lofexidine	Lofexidine The therapeutic efficacy of Vilazodone can be increased when used in combination with Lofexidine.
Eliglustat	Eliglustat The metabolism of Eliglustat can be decreased when combined with Vilazodone.
Encorafenib	Encorafenib The metabolism of Encorafenib can be decreased when combined with Vilazodone.
Elagolix	Elagolix The metabolism of Elagolix can be decreased when combined with Vilazodone.
Tafenoquine	Tafenoquine The metabolism of Tafenoquine can be decreased when combined with Vilazodone.
Cannabidiol	Cannabidiol The risk or severity of adverse effects can be increased when Cannabidiol is combined with Vilazodone.
Dacomitinib	Dacomitinib The metabolism of Vilazodone can be decreased when combined with Dacomitinib.
Stiripentol	Stiripentol The metabolism of Vilazodone can be decreased when combined with Stiripentol.
Gilteritinib	Gilteritinib The therapeutic efficacy of Vilazodone can be decreased when used in combination with Gilteritinib.
Lorlatinib	Lorlatinib The metabolism of Lorlatinib can be decreased when combined with Vilazodone.
Rifamycin	Rifamycin The metabolism of Vilazodone can be increased when combined with Rifamycin.
Emapalumab-lzsg Injection	Emapalumab-lzsg Injection The metabolism of Vilazodone can be increased when combined with Emapalumab.
Siponimod	Siponimod The risk or severity of hypertension can be increased when Vilazodone is combined with Siponimod.
Esomeprazole Injection	Esomeprazole Injection The metabolism of Vilazodone can be decreased when combined with Esomeprazole.
Alpelisib	Alpelisib The metabolism of Vilazodone can be decreased when combined with Alpelisib.
Brexanolone Injection	Brexanolone Injection The risk or severity of adverse effects can be increased when Vilazodone is combined with Brexanolone.
Solriamfetol	Solriamfetol The risk or severity of hypertension can be increased when Solriamfetol is combined with Vilazodone.
Triclabendazole	Triclabendazole The metabolism of Triclabendazole can be decreased when combined with Vilazodone.
Istradefylline	Istradefylline The metabolism of Istradefylline can be decreased when combined with Vilazodone.
Pitolisant	Pitolisant The serum concentration of Vilazodone can be decreased when it is combined with Pitolisant.
Fedratinib	Fedratinib The metabolism of Fedratinib can be decreased when combined with Vilazodone.
Phenytoin Injection	Phenytoin Injection The metabolism of Vilazodone can be increased when combined with Phenytoin.
Fosphenytoin Injection	Fosphenytoin Injection The metabolism of Vilazodone can be increased when combined with Fosphenytoin.
Voxelotor	Voxelotor The metabolism of Voxelotor can be decreased when combined with Vilazodone.
Lumateperone	Lumateperone The risk or severity of adverse effects can be increased when Vilazodone is combined with Lumateperone.
Lasmiditan	Lasmiditan The risk or severity of serotonin syndrome can be increased when Vilazodone is combined with Lasmiditan.
Cenobamate	Cenobamate The serum concentration of Vilazodone can be decreased when it is combined with Cenobamate.
Selumetinib	Selumetinib The metabolism of Selumetinib can be decreased when combined with Vilazodone.
Tucatinib	Tucatinib The metabolism of Tucatinib can be decreased when combined with Vilazodone.
Selpercatinib	Selpercatinib The risk or severity of hypertension can be increased when Vilazodone is combined with Selpercatinib.
Lemborexant	Lemborexant The risk or severity of adverse effects can be increased when Vilazodone is combined with Lemborexant.
Fenfluramine	Fenfluramine The risk or severity of serotonin syndrome can be increased when Fenfluramine is combined with Vilazodone.
Satralizumab-mwge Injection	Satralizumab-mwge Injection The serum concentration of Vilazodone can be decreased when it is combined with Satralizumab.
Naxitamab-gqgk Injection	Naxitamab-gqgk Injection The risk or severity of hypertension can be increased when Vilazodone is combined with Naxitamab.
Viloxazine	Viloxazine The risk or severity of adverse effects can be increased when Vilazodone is combined with Viloxazine.
Theophylline	Theophylline The metabolism of Theophylline can be decreased when combined with Vilazodone.
Fenoprofen	Fenoprofen The risk or severity of hypertension can be increased when Fenoprofen is combined with Vilazodone.
Indomethacin	Indomethacin The metabolism of Vilazodone can be decreased when combined with Indomethacin.
Mefenamic Acid	Mefenamic Acid The risk or severity of hypertension can be increased when Mefenamic acid is combined with Vilazodone.
Naproxen	Naproxen The risk or severity of hypertension can be increased when Naproxen is combined with Vilazodone.
Tolmetin	Tolmetin The risk or severity of hypertension can be increased when Tolmetin is combined with Vilazodone.
Sulindac	Sulindac The risk or severity of hypertension can be increased when Sulindac is combined with Vilazodone.
Trazodone	Trazodone The risk or severity of serotonin syndrome can be increased when Trazodone is combined with Vilazodone.
Hydroxyurea	Hydroxyurea The metabolism of Vilazodone can be decreased when combined with Hydroxyurea.
Phenobarbital	Phenobarbital The metabolism of Vilazodone can be increased when combined with Phenobarbital.
Metaxalone	Metaxalone The risk or severity of adverse effects can be increased when Metaxalone is combined with Vilazodone.
Levorphanol	Levorphanol The risk or severity of adverse effects can be increased when Levorphanol is combined with Vilazodone.
Primidone	Primidone The metabolism of Vilazodone can be increased when combined with Primidone.
Methsuximide	Methsuximide The risk or severity of adverse effects can be increased when Methsuximide is combined with Vilazodone.
Diethylpropion	Diethylpropion The risk or severity of adverse effects can be increased when Diethylpropion is combined with Vilazodone.
Chlorpromazine	Chlorpromazine The metabolism of Vilazodone can be decreased when combined with Chlorpromazine.
Diazepam	Diazepam The risk or severity of adverse effects can be increased when Diazepam is combined with Vilazodone.
Oxazepam	Oxazepam The risk or severity of adverse effects can be increased when Oxazepam is combined with Vilazodone.
Flurazepam	Flurazepam The risk or severity of adverse effects can be increased when Flurazepam is combined with Vilazodone.
Clorazepate	Clorazepate The risk or severity of adverse effects can be increased when Clorazepic acid is combined with Vilazodone.
Lorazepam	Lorazepam The risk or severity of adverse effects can be increased when Lorazepam is combined with Vilazodone.
Phenoxybenzamine	Phenoxybenzamine The risk or severity of hypertension can be increased when Phenoxybenzamine is combined with Vilazodone.
Amantadine	Amantadine The risk or severity of serotonin syndrome can be increased when Amantadine is combined with Vilazodone.
Codeine	Codeine The metabolism of Vilazodone can be decreased when combined with Codeine.
Meprobamate	Meprobamate The risk or severity of adverse effects can be increased when Meprobamate is combined with Vilazodone.
Chlordiazepoxide	Chlordiazepoxide The risk or severity of adverse effects can be increased when Chlordiazepoxide is combined with Vilazodone.
Bromocriptine	Bromocriptine Bromocriptine may increase the vasoconstricting activities of Vilazodone.
Metaproterenol	Metaproterenol The risk or severity of hypertension can be increased when Orciprenaline is combined with Vilazodone.
Tranylcypromine	Tranylcypromine The metabolism of Vilazodone can be decreased when combined with Tranylcypromine.
Phenelzine	Phenelzine The metabolism of Vilazodone can be decreased when combined with Phenelzine.
Procarbazine	Procarbazine The metabolism of Vilazodone can be decreased when combined with Procarbazine.
Ergoloid Mesylates	Ergoloid Mesylates Ergoloid mesylate may increase the vasoconstricting activities of Vilazodone.
Minocycline	Minocycline Minocycline may increase the central nervous system depressant (CNS depressant) activities of Vilazodone.
Prochlorperazine	Prochlorperazine The metabolism of Vilazodone can be decreased when combined with Prochlorperazine.
Thioridazine	Thioridazine The metabolism of Vilazodone can be decreased when combined with Thioridazine.
Trifluoperazine	Trifluoperazine The risk or severity of adverse effects can be increased when Trifluoperazine is combined with Vilazodone.
Oxycodone	Oxycodone The metabolism of Vilazodone can be decreased when combined with Oxycodone.
Methadone	Methadone The risk or severity of adverse effects can be increased when Methadone is combined with Vilazodone.
Oxybutynin	Oxybutynin The metabolism of Vilazodone can be decreased when combined with Oxybutynin.
Benztropine	Benztropine The metabolism of Benzatropine can be decreased when combined with Vilazodone.
Maprotiline	Maprotiline The metabolism of Vilazodone can be decreased when combined with Maprotiline.
Ibuprofen	Ibuprofen The risk or severity of hypertension can be increased when Ibuprofen is combined with Vilazodone.
Trihexyphenidyl	Trihexyphenidyl Vilazodone may increase the central nervous system depressant (CNS depressant) activities of Trihexyphenidyl.
Orphenadrine	Orphenadrine Vilazodone may increase the central nervous system depressant (CNS depressant) activities of Orphenadrine.
Perphenazine	Perphenazine The metabolism of Vilazodone can be decreased when combined with Perphenazine.
Fluphenazine	Fluphenazine The risk or severity of adverse effects can be increased when Fluphenazine is combined with Vilazodone.
Phentermine	Phentermine The risk or severity of serotonin syndrome can be increased when Phentermine is combined with Vilazodone.
Methylphenidate	Methylphenidate The risk or severity of hypertension can be increased when Methylphenidate is combined with Vilazodone.
Amoxapine	Amoxapine The metabolism of Vilazodone can be decreased when combined with Amoxapine.
Sulfasalazine	Sulfasalazine The risk or severity of hypertension can be increased when Sulfasalazine is combined with Vilazodone.
Doxorubicin	Doxorubicin The metabolism of Vilazodone can be decreased when combined with Doxorubicin.
Carbamazepine	Carbamazepine The metabolism of Vilazodone can be increased when combined with Carbamazepine.
Molindone	Molindone The risk or severity of adverse effects can be increased when Molindone is combined with Vilazodone.
Methyldopa	Methyldopa Vilazodone may decrease the antihypertensive activities of Methyldopa.
Clonidine	Clonidine The risk or severity of sedation can be increased when Clonidine is combined with Vilazodone.
Prazosin	Prazosin Vilazodone may decrease the antihypertensive activities of Prazosin.
Hydralazine	Hydralazine Vilazodone may decrease the antihypertensive activities of Hydralazine.
Cimetidine	Cimetidine The metabolism of Vilazodone can be decreased when combined with Cimetidine.
Warfarin	Warfarin The metabolism of Vilazodone can be decreased when combined with Warfarin.
Clonazepam	Clonazepam The risk or severity of adverse effects can be increased when Clonazepam is combined with Vilazodone.
Loperamide	Loperamide The metabolism of Vilazodone can be decreased when combined with Loperamide.
Promethazine	Promethazine The metabolism of Vilazodone can be decreased when combined with Promethazine.
Meclofenamate	Meclofenamate The risk or severity of hypertension can be increased when Meclofenamic acid is combined with Vilazodone.
Digoxin	Digoxin The serum concentration of Digoxin can be increased when it is combined with Vilazodone.
Loxapine	Loxapine The risk or severity of adverse effects can be increased when Loxapine is combined with Vilazodone.
Chloroquine	Chloroquine The metabolism of Vilazodone can be decreased when combined with Chloroquine.
Quinine	Quinine The metabolism of Vilazodone can be decreased when combined with Quinine.
Ethosuximide	Ethosuximide The risk or severity of adverse effects can be increased when Ethosuximide is combined with Vilazodone.
Chlorothiazide	Chlorothiazide Vilazodone may decrease the antihypertensive activities of Chlorothiazide.
Chlorthalidone	Chlorthalidone Vilazodone may decrease the antihypertensive activities of Chlorthalidone.
Metolazone	Metolazone Vilazodone may decrease the antihypertensive activities of Metolazone.
Secobarbital	Secobarbital The risk or severity of adverse effects can be increased when Secobarbital is combined with Vilazodone.
Desipramine	Desipramine The metabolism of Vilazodone can be decreased when combined with Desipramine.
Amitriptyline	Amitriptyline The metabolism of Amitriptyline can be decreased when combined with Vilazodone.
Imipramine	Imipramine The metabolism of Vilazodone can be decreased when combined with Imipramine.
Probenecid	Probenecid The metabolism of Vilazodone can be decreased when combined with Probenecid.
Quinidine	Quinidine The metabolism of Vilazodone can be decreased when combined with Quinidine.
Procainamide	Procainamide The metabolism of Procainamide can be decreased when combined with Vilazodone.
Isoniazid	Isoniazid The metabolism of Vilazodone can be decreased when combined with Isoniazid.
Rifampin	Rifampin The metabolism of Vilazodone can be increased when combined with Rifampicin.
Disopyramide	Disopyramide Vilazodone may increase the central nervous system depressant (CNS depressant) activities of Disopyramide.
Valproic Acid	Valproic Acid The risk or severity of adverse effects can be increased when Valproic acid is combined with Vilazodone.
Tamoxifen	Tamoxifen The metabolism of Vilazodone can be decreased when combined with Tamoxifen.
Butabarbital	Butabarbital The risk or severity of adverse effects can be increased when Butabarbital is combined with Vilazodone.
Methimazole	Methimazole The metabolism of Vilazodone can be decreased when combined with Methimazole.
Dextromethorphan	Dextromethorphan The metabolism of Vilazodone can be decreased when combined with Dextromethorphan.
Cyclobenzaprine	Cyclobenzaprine The risk or severity of CNS depression can be increased when Vilazodone is combined with Cyclobenzaprine.
Niacin	Niacin The metabolism of Vilazodone can be decreased when combined with Niacin.
Baclofen	Baclofen The risk or severity of adverse effects can be increased when Baclofen is combined with Vilazodone.
Doxylamine	Doxylamine Doxylamine may increase the central nervous system depressant (CNS depressant) activities of Vilazodone.
Cyproheptadine	Cyproheptadine The risk or severity of adverse effects can be increased when Cyproheptadine is combined with Vilazodone.
Clemastine	Clemastine The metabolism of Vilazodone can be decreased when combined with Clemastine.
Chlorpheniramine	Chlorpheniramine The metabolism of Vilazodone can be decreased when combined with Chlorpheniramine.
Brompheniramine	Brompheniramine The risk or severity of adverse effects can be increased when Dexbrompheniramine is combined with Vilazodone.
Meclizine	Meclizine The metabolism of Vilazodone can be decreased when combined with Meclizine.
Hydrochlorothiazide	Hydrochlorothiazide Vilazodone may decrease the antihypertensive activities of Hydrochlorothiazide.
Dantrolene	Dantrolene The risk or severity of adverse effects can be increased when Dantrolene is combined with Vilazodone.
Chlorzoxazone	Chlorzoxazone The metabolism of Chlorzoxazone can be decreased when combined with Vilazodone.
Carisoprodol	Carisoprodol The risk or severity of adverse effects can be increased when Carisoprodol is combined with Vilazodone.
Methocarbamol	Methocarbamol The risk or severity of adverse effects can be increased when Methocarbamol is combined with Vilazodone.
Propranolol (Cardiovascular)	Propranolol (Cardiovascular) The metabolism of Propranolol can be decreased when combined with Vilazodone.
Minoxidil	Minoxidil Vilazodone may decrease the antihypertensive activities of Minoxidil.
Pseudoephedrine	Pseudoephedrine The risk or severity of serotonin syndrome can be increased when Pseudoephedrine is combined with Vilazodone.
Nortriptyline	Nortriptyline The metabolism of Vilazodone can be decreased when combined with Nortriptyline.
Nadolol	Nadolol The metabolism of Nadolol can be decreased when combined with Vilazodone.
Butorphanol Injection	Butorphanol Injection The risk or severity of adverse effects can be increased when Butorphanol is combined with Vilazodone.
Nalbuphine Injection	Nalbuphine Injection The risk or severity of adverse effects can be increased when Nalbuphine is combined with Vilazodone.
Trimethobenzamide	Trimethobenzamide The risk or severity of adverse effects can be increased when Trimethobenzamide is combined with Vilazodone.
Flavoxate	Flavoxate Vilazodone may increase the central nervous system depressant (CNS depressant) activities of Flavoxate.
Acetazolamide	Acetazolamide The risk or severity of adverse effects can be increased when Acetazolamide is combined with Vilazodone.
Ketoconazole	Ketoconazole The metabolism of Vilazodone can be decreased when combined with Ketoconazole.
Pyrantel	Pyrantel The risk or severity of adverse effects can be increased when Vilazodone is combined with Pyrantel.
Captopril	Captopril Vilazodone may decrease the antihypertensive activities of Captopril.
Isoxsuprine	Isoxsuprine The risk or severity of hypertension can be increased when Vilazodone is combined with Isoxsuprine.
Vinblastine	Vinblastine The metabolism of Vilazodone can be decreased when combined with Vinblastine.
Metoprolol	Metoprolol The metabolism of Vilazodone can be decreased when combined with Metoprolol.
Hydroxyzine	Hydroxyzine Hydroxyzine may increase the central nervous system depressant (CNS depressant) activities of Vilazodone.
Thiothixene	Thiothixene The risk or severity of adverse effects can be increased when Thiothixene is combined with Vilazodone.
Aspirin	Aspirin The risk or severity of hypertension can be increased when Acetylsalicylic acid is combined with Vilazodone.
Salsalate	Salsalate The risk or severity of hypertension can be increased when Salsalate is combined with Vilazodone.
Alprazolam	Alprazolam The risk or severity of adverse effects can be increased when Alprazolam is combined with Vilazodone.
Temazepam	Temazepam The risk or severity of adverse effects can be increased when Temazepam is combined with Vilazodone.
Triazolam	Triazolam The risk or severity of adverse effects can be increased when Triazolam is combined with Vilazodone.
Dicyclomine	Dicyclomine Vilazodone may increase the central nervous system depressant (CNS depressant) activities of Dicyclomine.
Hyoscyamine	Hyoscyamine Vilazodone may increase the central nervous system depressant (CNS depressant) activities of Hyoscyamine.
Propantheline	Propantheline Vilazodone may increase the central nervous system depressant (CNS depressant) activities of Propantheline.
Diltiazem	Diltiazem The metabolism of Vilazodone can be decreased when combined with Diltiazem.
Nifedipine	Nifedipine The metabolism of Vilazodone can be decreased when combined with Nifedipine.
Timolol	Timolol The metabolism of Timolol can be decreased when combined with Vilazodone.
Verapamil	Verapamil The metabolism of Vilazodone can be decreased when combined with Verapamil.
Atenolol	Atenolol The metabolism of Atenolol can be decreased when combined with Vilazodone.
Pindolol	Pindolol The metabolism of Vilazodone can be decreased when combined with Pindolol.
Diflunisal	Diflunisal The risk or severity of hypertension can be increased when Diflunisal is combined with Vilazodone.
Piroxicam	Piroxicam The risk or severity of hypertension can be increased when Piroxicam is combined with Vilazodone.
Glyburide	Glyburide The metabolism of Vilazodone can be decreased when combined with Glyburide.
Indapamide	Indapamide Vilazodone may decrease the antihypertensive activities of Indapamide.
Pentamidine Injection	Pentamidine Injection The metabolism of Pentamidine can be decreased when combined with Vilazodone.
Labetalol	Labetalol The metabolism of Vilazodone can be decreased when combined with Labetalol.
Gemfibrozil	Gemfibrozil The metabolism of Vilazodone can be decreased when combined with Gemfibrozil.
Guanabenz	Guanabenz The risk or severity of hypertension can be increased when Guanabenz is combined with Vilazodone.
Ketoprofen	Ketoprofen The risk or severity of hypertension can be increased when Ketoprofen is combined with Vilazodone.
Pimozide	Pimozide The metabolism of Vilazodone can be decreased when combined with Pimozide.
Enalapril	Enalapril Vilazodone may decrease the antihypertensive activities of Enalapril.
Flurbiprofen	Flurbiprofen The risk or severity of hypertension can be increased when Flurbiprofen is combined with Vilazodone.
Amiodarone	Amiodarone The metabolism of Vilazodone can be decreased when combined with Amiodarone.
Buspirone	Buspirone The metabolism of Buspirone can be decreased when combined with Vilazodone.
Lovastatin	Lovastatin The metabolism of Vilazodone can be decreased when combined with Lovastatin.
Mesalamine	Mesalamine The risk or severity of hypertension can be increased when Mesalazine is combined with Vilazodone.
Diclofenac	Diclofenac The risk or severity of hypertension can be increased when Diclofenac is combined with Vilazodone.
Fluoxetine	Fluoxetine The serum concentration of Vilazodone can be increased when it is combined with Fluoxetine.
Nimodipine	Nimodipine Vilazodone may decrease the antihypertensive activities of Nimodipine.
Clozapine	Clozapine The metabolism of Vilazodone can be decreased when combined with Clozapine.
Estazolam	Estazolam The risk or severity of adverse effects can be increased when Estazolam is combined with Vilazodone.
Idarubicin	Idarubicin The metabolism of Idarubicin can be decreased when combined with Vilazodone.
Clarithromycin	Clarithromycin The metabolism of Vilazodone can be decreased when combined with Clarithromycin.
Benazepril	Benazepril Vilazodone may decrease the antihypertensive activities of Benazepril.
Etodolac	Etodolac The risk or severity of hypertension can be increased when Etodolac is combined with Vilazodone.
Felodipine	Felodipine The metabolism of Vilazodone can be decreased when combined with Felodipine.
Fosinopril	Fosinopril Vilazodone may decrease the antihypertensive activities of Fosinopril.
Nabumetone	Nabumetone The risk or severity of hypertension can be increased when Nabumetone is combined with Vilazodone.
Quinapril	Quinapril Vilazodone may decrease the antihypertensive activities of Quinapril.
Ramipril	Ramipril Vilazodone may decrease the antihypertensive activities of Ramipril.
Simvastatin	Simvastatin The metabolism of Simvastatin can be decreased when combined with Vilazodone.
Amlodipine	Amlodipine Vilazodone may decrease the antihypertensive activities of Amlodipine.
Itraconazole	Itraconazole The metabolism of Vilazodone can be decreased when combined with Itraconazole.
Lisinopril	Lisinopril Vilazodone may decrease the antihypertensive activities of Lisinopril.
Oxaprozin	Oxaprozin The risk or severity of hypertension can be increased when Oxaprozin is combined with Vilazodone.
Rifabutin	Rifabutin The metabolism of Vilazodone can be increased when combined with Rifabutin.
Sotalol	Sotalol The metabolism of Sotalol can be decreased when combined with Vilazodone.
Bisoprolol	Bisoprolol Vilazodone may decrease the antihypertensive activities of Bisoprolol.
Zolpidem	Zolpidem Vilazodone may increase the central nervous system depressant (CNS depressant) activities of Zolpidem.
Doxazosin	Doxazosin The metabolism of Doxazosin can be decreased when combined with Vilazodone.
Terazosin	Terazosin Vilazodone may decrease the antihypertensive activities of Terazosin.
Isradipine	Isradipine Vilazodone may decrease the antihypertensive activities of Isradipine.
Omeprazole	Omeprazole The metabolism of Vilazodone can be decreased when combined with Omeprazole.
Cisapride	Cisapride The metabolism of Vilazodone can be decreased when combined with Cisapride.
Gabapentin	Gabapentin The risk or severity of adverse effects can be increased when Gabapentin is combined with Vilazodone.
Fluvastatin	Fluvastatin The metabolism of Vilazodone can be decreased when combined with Fluvastatin.
Venlafaxine	Venlafaxine The metabolism of Vilazodone can be decreased when combined with Venlafaxine.
Fluvoxamine	Fluvoxamine The metabolism of Vilazodone can be decreased when combined with Fluvoxamine.
Nefazodone	Nefazodone The metabolism of Vilazodone can be decreased when combined with Nefazodone.
Lamotrigine	Lamotrigine The risk or severity of adverse effects can be increased when Lamotrigine is combined with Vilazodone.
Losartan	Losartan The metabolism of Losartan can be decreased when combined with Vilazodone.
Tramadol	Tramadol The risk or severity of serotonin syndrome can be increased when Tramadol is combined with Vilazodone.
Vinorelbine Injection	Vinorelbine Injection The metabolism of Vilazodone can be decreased when combined with Vinorelbine.
Moexipril	Moexipril Vilazodone may decrease the antihypertensive activities of Moexipril.
Lansoprazole	Lansoprazole The metabolism of Vilazodone can be decreased when combined with Lansoprazole.
Nicardipine	Nicardipine The metabolism of Vilazodone can be decreased when combined with Nicardipine.
Bupropion	Bupropion The metabolism of Vilazodone can be decreased when combined with Bupropion.
Ticlopidine	Ticlopidine The metabolism of Ticlopidine can be decreased when combined with Vilazodone.
Saquinavir	Saquinavir The metabolism of Saquinavir can be decreased when combined with Vilazodone.
Nisoldipine	Nisoldipine Vilazodone may decrease the antihypertensive activities of Nisoldipine.
Riluzole	Riluzole The risk or severity of adverse effects can be increased when Riluzole is combined with Vilazodone.
Ritonavir	Ritonavir The metabolism of Vilazodone can be decreased when combined with Ritonavir.
Clomipramine	Clomipramine The metabolism of Vilazodone can be decreased when combined with Clomipramine.
Zafirlukast	Zafirlukast The metabolism of Vilazodone can be decreased when combined with Zafirlukast.
Mirtazapine	Mirtazapine Vilazodone may increase the serotonergic activities of Mirtazapine.
Trandolapril	Trandolapril Vilazodone may decrease the antihypertensive activities of Trandolapril.
Topiramate	Topiramate The risk or severity of adverse effects can be increased when Topiramate is combined with Vilazodone.
Valsartan	Valsartan Vilazodone may decrease the antihypertensive activities of Valsartan.
Pramipexole	Pramipexole Vilazodone may increase the sedative activities of Pramipexole.
Donepezil	Donepezil The metabolism of Donepezil can be decreased when combined with Vilazodone.
Nelfinavir	Nelfinavir The metabolism of Vilazodone can be decreased when combined with Nelfinavir.
Carvedilol	Carvedilol The metabolism of Carvedilol can be decreased when combined with Vilazodone.
Nilutamide	Nilutamide The metabolism of Vilazodone can be decreased when combined with Nilutamide.
Selegiline	Selegiline The metabolism of Vilazodone can be decreased when combined with Selegiline.
Bicalutamide	Bicalutamide The metabolism of Vilazodone can be decreased when combined with Bicalutamide.
Sertraline	Sertraline The metabolism of Vilazodone can be decreased when combined with Sertraline.
Propafenone	Propafenone The metabolism of Vilazodone can be decreased when combined with Propafenone.
Letrozole	Letrozole The metabolism of Vilazodone can be decreased when combined with Letrozole.
Irbesartan	Irbesartan Vilazodone may decrease the antihypertensive activities of Irbesartan.
Tamsulosin	Tamsulosin The metabolism of Tamsulosin can be decreased when combined with Vilazodone.
Ropinirole	Ropinirole Vilazodone may increase the sedative activities of Ropinirole.
Finasteride	Finasteride The risk or severity of hypertension can be increased when Finasteride is combined with Vilazodone.
Quetiapine	Quetiapine The metabolism of Vilazodone can be decreased when combined with Quetiapine.
Cetirizine	Cetirizine The risk or severity of adverse effects can be increased when Cetirizine is combined with Vilazodone.
Paroxetine	Paroxetine The metabolism of Vilazodone can be decreased when combined with Paroxetine.
Tolcapone	Tolcapone The risk or severity of adverse effects can be increased when Tolcapone is combined with Vilazodone.
Citalopram	Citalopram The metabolism of Vilazodone can be decreased when combined with Citalopram.
Efavirenz	Efavirenz The metabolism of Vilazodone can be decreased when combined with Efavirenz.
Sildenafil	Sildenafil The metabolism of Sildenafil can be decreased when combined with Vilazodone.
Celecoxib	Celecoxib The metabolism of Vilazodone can be decreased when combined with Celecoxib.
Rosiglitazone	Rosiglitazone The metabolism of Vilazodone can be decreased when combined with Rosiglitazone.
Tolterodine	Tolterodine The metabolism of Tolterodine can be decreased when combined with Vilazodone.
Thalidomide	Thalidomide Vilazodone may increase the central nervous system depressant (CNS depressant) activities of Thalidomide.
Balsalazide	Balsalazide The risk or severity of hypertension can be increased when Balsalazide is combined with Vilazodone.
Nateglinide	Nateglinide The metabolism of Nateglinide can be decreased when combined with Vilazodone.
Galantamine	Galantamine The metabolism of Galantamine can be decreased when combined with Vilazodone.
Levetiracetam	Levetiracetam The risk or severity of adverse effects can be increased when Levetiracetam is combined with Vilazodone.
Rabeprazole	Rabeprazole The metabolism of Vilazodone can be decreased when combined with Rabeprazole.
Terbinafine	Terbinafine The metabolism of Vilazodone can be decreased when combined with Terbinafine.