Label image from the product's FDA listing (DailyMed) — may show a different pack size or an older label revision.
REFRESH TEARS carboxymethylcellulose sodium 5 mg/mL Solution/ Drops — NDC 0023-0798-02 (Billing 00023-0798-02)
by Allergan, Inc. · 4 BOTTLE, DROPPER in 1 CARTON / 15 mL in 1 BOTTLE, DROPPER
This is a package of REFRESH TEARS carboxymethylcellulose sodium 5 mg/mL Solution/ Drops from Allergan, Inc., no longer marketed (first marketed May 1997), no longer in the FDA NDC Directory.
NDC 00023-0798-02
🏷️ FDA NDC (as labeled)
0023-0798-02
billing pads the labeler segment with a zero
This package
Contains15 mL in 1 bottle, dropper
Pack sizes5 compare ↓
Product page 00023-0798-15
Also comes in:
3 mL 0023-0798-03
3 mL 0023-0798-04
15 mL 0023-0798-15
2 bottles 0023-0798-01
🗂️ FDA directory synced Oct 1, 2026 · this listing last changed Jul 24, 2026 · sources: openFDA · FDA label (DailyMed) · FDA Orange & Purple Book · First Databank · CMS NADAC, ASP, Medicare & Medicaid · RxNorm
📋 All sources & update times →
⚠️
Other active recalls for Carboxymethylcellulose Sodium (different manufacturers) — 6 · tap to view
These affect other manufacturers’ products for the same ingredient — not necessarily the exact NDC on this page.
Class II · Apr 23, 2025 — cGMP deviations and lack of assurance of sterility. (BRS Analytical Services, LLC) · FDA recall D-0406-2025
Class III · Dec 18, 2024 — LABELING: LABEL MIX-UP (AvKARE) · FDA recall D-0175-2025
Class I · Nov 13, 2023 — Non-Sterility (Kilitch Healthcare India Limited) · FDA recall D-0291-2024
Class I · Nov 13, 2023 — Non-Sterility (Kilitch Healthcare India Limited) · FDA recall D-0299-2024
Class I · Oct 31, 2023 — Non-Sterility: FDA found insanitary conditions and positive bacterial test results from environmental sampling at the manufacturing facility. (Cardinal Health Inc.) · FDA recall D-0134-2024
Class I · Oct 31, 2023 — Non-Sterility: FDA found insanitary conditions and positive bacterial test results from environmental sampling at the manufacturing facility. (Cardinal Health Inc.) · FDA recall D-0132-2024
Each entry is an official FDA enforcement report — look up any recall number in the FDA recall database ↗
⚠️
Excluded from the active FDA NDC Directory.
The labeler reported this product as discontinued, so it is excluded from the active NDC Directory. A label may still appear on DailyMed, but the NDC is no longer in the current FDA NDC Directory.
Search the FDA NDC Directory ↗
Identity & classification
Regulatory identifiers FDA, NLM and CMS codes for this package
FDA NDC (as labeled)
0023-0798-02
Product NDC
0023-0798
11-digit billing NDC
00023079802
NCPDP billing unit
ML — per mL (volume)
RxCUI
1188426
UNII
K679OBS311
Application #
M018
SPL Set ID
329d1fe0-4432-4565-b7b1-65666bd86526
DEA schedule
Non-controlled
Marketing category
OTC MONOGRAPH DRUG
Marketing status
Discontinued
FDA listing status
Discontinued by firm
Marketing start
1997-05-16
Route
OPHTHALMIC
Dosage form
SOLUTION/ DROPS
Substance
CARBOXYMETHYLCELLULOSE SODIUM
Drug-database identifiers Medi-Span GPI and First Databank GCN / HICL / AHFS classification
GPI-14
86200010102020
GPI class
Refresh Tears
GCN Seq No
016278
GCN
37381
HICL code
003843
Ingredient (HICL)
Carboxymethylcellulose Sodium
HIC1 code
Q
Therapeutic class — broad (HIC1)
Ear/Eye/Nose/Rectum/Topical/Vagina/Other
HIC2 code
Q6
Therapeutic class — intermediate (HIC2)
Ophthalmic Preparations
HIC3 code
Q6T
Therapeutic class — specific (HIC3)
Artificial Tears
AHFS code
52:92.00.00
AHFS class
Eent Drugs, Miscellaneous
FDB label name
REFRESH TEARS 0.5% EYE DROP
FDB brand name
Refresh Tears
Legend status
O — Over-the-counter (OTC) drug or device
Quick answers
- GSN (GCN sequence number): 016278
- GCN: 37381
- GPI-14 (Medi-Span): 86200010102020
- HICL (First Databank): 003843
- AHFS class code: 52:92.00.00
- RxCUI (RxNorm): 1188426
Why two NDCs?
The FDA registers this code as 0023-0798-02 — a 4-4-2 layout, and that's what's printed on the package and shown on DailyMed. For insurance claims, every NDC is standardized to a uniform 11-digit 5-4-2 format by adding a zero to the labeler segment → 00023-0798-02. Same drug, same package — only the format differs.
Where does this data come from?
Identifiers from the FDA openFDA NDC Directory and Structured Product Labeling; RxCUI from RxNorm (NLM); GPI from Medi-Span; GCN / HIC / AHFS / legend from First Databank.
- FDA openFDA NDC Directory · synced Oct 1, 2026
- FDA label on DailyMed · label index refreshed Oct 1, 2026
- RxNorm (NLM RxNav) · catalog refreshed Oct 1, 2026
- Medi-Span GPI (licensed)
- First Databank (licensed) · refreshed Oct 1, 2026
Clinical
Label name REFRESH TEARS 0.5% EYE DROP Ingredient Carboxymethylcellulose Sodium
🧪 What is this product?
Refresh Tears is an over-the-counter eye drop solution containing carboxymethylcellulose sodium, a type of lubricant. It is typically used to temporarily relieve dry eyes and eye irritation by providing moisture to the eye surface. This product is marketed as an OTC monograph drug, meaning it follows established FDA guidelines for over-the-counter eye lubricants rather than being individually reviewed as a new drug application.
Patient education
Supplement & herbal interactions
Where does this data come from?
Plain-language summary from MedlinePlus (U.S. National Library of Medicine); supplement & herbal interactions and nutrient depletion data from the Natural Medicines database; our full guide is HelloPharmacist editorial content.
- MedlinePlus (NLM) · refreshed Oct 1, 2026
- FDA label on DailyMed · label index refreshed Oct 1, 2026
💬 Questions about carboxymethylcellulose sodium?
Ask a pharmacist →
Ask a licensed pharmacist directly — free, answered by our team.
Pricing
A drug doesn't have one price. Each row is a different public payment system, and none is what you'd pay at the counter — that depends on your insurance. The ⓘ on each row explains what it measures.
| Price system | Per mL | Per package |
|---|---|---|
| Retail pharmacies payNADAC · weekly | Not in the retail survey — common for institutional, discontinued, or low-volume packs. | |
| Medicaid paysCMS SDUD · 12 mo | No recent Medicaid claims on file for this NDC — rare and low-volume NDCs are suppressed in the public data. | |
| Medicare drug plans payPart D · quarterly | No Part D plan price is available for this NDC in our data. | |
ℹ️
Where does this data come from?
NADAC (National Average Drug Acquisition Cost) is the CMS weekly pharmacy-acquisition-cost survey — what pharmacies pay. ASP (Average Sales Price) is the CMS Medicare Part B drug-payment file, published quarterly. Medicaid pays is computed by us from CMS State Drug Utilization Data (total reimbursed ÷ units, trailing 12 months) — gross of rebates and inclusive of dispensing fees, so it reflects what Medicaid paid, not an acquisition cost. Medicare drug plans pay is the median negotiated point-of-sale unit cost across plans listing this NDC in the CMS quarterly Prescription Drug Plan pricing files, before rebates. The VA pays is the federal contract price (FSS, and the statutory Big 4 ceiling where listed) from the VA National Acquisition Center pharmaceutical price file. All are free public government data; each measures a different payer, so the figures are not directly comparable.
- CMS NADAC weekly file
- CMS ASP pricing files · refreshed Sep 20, 2026
- CMS Medicaid State Drug Utilization Data · refreshed Oct 3, 2026
- CMS Part D plan pricing files · refreshed Sep 24, 2026
- VA National Acquisition Center price file
Packaging — all sizes for this product
| Package NDC | Description | Per unit | Per pack | Marketing start | Marketing end | Status |
|---|---|---|---|---|---|---|
| 00023-0798-01 0023-0798-01 | 2 BOTTLE, DROPPER in 1 CARTON / 15 mL in 1 BOTTLE, DROPPER | $0.4117 / mL | $12.35 | 1997-05-16 | — | Active |
| 00023-0798-02 You're viewing this | 4 BOTTLE, DROPPER in 1 CARTON / 15 mL in 1 BOTTLE, DROPPER | — | — | 1997-05-16 | — | Discontinued by firm |
| 00023-0798-03 0023-0798-03 | 1 BOTTLE, DROPPER in 1 CARTON / 3 mL in 1 BOTTLE, DROPPER Sample | — | — | 1997-05-16 | — | Active |
| 00023-0798-04 0023-0798-04 | 1 BOTTLE, DROPPER in 1 CARTON / 3 mL in 1 BOTTLE, DROPPER Sample | — | — | 1997-05-16 | — | Active |
| 00023-0798-15 0023-0798-15 Main listing | 1 BOTTLE, DROPPER in 1 CARTON / 15 mL in 1 BOTTLE, DROPPER | $0.5578 / mL | $8.37 | 1997-05-16 | — | Active |
This pack shows little to no recent Medicaid volume — a different pack size carries most fills. See all packs ↓
Pack size FAQ
What quantity is in this package?
This package is listed by the FDA — 4 bottle, dropper in 1 carton / 15 ml in 1 bottle, dropper.
What NDC number is used to bill for this package of REFRESH TEARS carboxymethylcellulose sodium 5 mg/mL Solution/ Drops?
Use the 11-digit billing form listed in the identifiers section of this page. Pharmacy and medical claims use the 11-digit form; the FDA label may print a shorter form of the same code.
Prices are the latest CMS NADAC pharmacy acquisition cost per NDC; per-pack figures are per-unit × pack quantity, shown only when the pack is denominated in the same measure NADAC prices.
Therapeutic equivalents
| Product | Labeler | Pack | NADAC/unit | TE | Status | Price vs. this |
|---|---|---|---|---|---|---|
| Leader Lubricant Eye Drops .5 g/100mL 70000-0012-01 | Cardinal | 70 vials | $0.163 | — | Availability likely | — |
| Rugby Lubricant Eye Drops .5 g/100mL 00536-1387-92 | Rugby | 30 vials | $0.227 | — | Availability likely | — |
| Good Neighbor Pharmacy Lubricant Eye Drops .5 g/100mL 46122-0756-56 | Amerisource | 30 vials | $0.227 | — | Availability likely | — |
| carboxymethylcellulose sodium 5 mg/mL 50268-0067-30 | AvPAK | 30 vials | $0.227 | — | Availability likely | — |
| Foster and Thrive Lubricant Eye Drops .5 g/100mL 70677-1190-01 | Strategic | 30 vials | $0.227 | — | Availability likely | — |
| Carboxymethylcellulose Sodium Eye Lubricant 5 mg/mL 42494-0448-05 | Cameron | 2 bottles | $0.275 | — | Discontinued | — |
| Rugby Carboxymethylcellulose Sodium 0.5% Eye Drops .5 g/100mL 00536-1386-35 | Rugby | 2 bottles | $0.280 | — | Availability likely | — |
| carboxymethylcellulose sodium 5 mg/mL 50268-0068-15 | AvPAK | 1 bottle | $0.324 | — | Availability likely | — |
| Leader Lubricant Eye Drops Soothing Relief .5 g/100mL 70000-0705-01 | LEADER/Cardinal | 1 bottle | $0.324 | — | Availability likely | — |
| Lubricant Drops 5 mg/mL 70000-0090-01 | CARDINAL | 1 bottle | $0.498 | — | FDA listed | — |
| Refresh Plus 5 mg/mL 00023-0403-05 | Allergan, | 5 vials | — | — | FDA listed | — |
| Refresh Tears 00023-0795-65 | Allergan, | 1 kit | — | — | FDA listed | — |
| Refresh Tears 5 mg/mLthis 00023-0798-02 | Allergan, | 4 bottles | — | — | Discontinued | — |
| Walgreens Lubricant Eye Drops Preservative Free .5 g/100mL 00363-8800-01 | Walgreen | 30 vials | — | — | FDA listed | — |
| Walgreens Lubricant Eye Drops 5 mg/mL 00363-8832-15 | Walgreen | 2 bottles | — | — | FDA listed | — |
| Walgreens Lubricant Eye Drops 5 mg/mL 00363-8833-15 | Walgreen | 1 bottle | — | — | FDA listed | — |
| Lubricant Eye 5 mg/mL 00536-1476-92 | Rugby | 30 ampules | — | — | FDA listed | — |
| Lubricant Eye Drops Preservative Free .5 g/100mL 11673-0150-01 | Target | 70 vials | — | — | FDA listed | — |
| Up and Up Dry Eye Relief Lubricant Eye Drops 5 mg/mL 11673-0771-01 | Target | 2 bottles | — | — | FDA listed | — |
| Up and Up Dry Eye Relief Lubricant Eye Drops 5 mg/mL 11716-0771-01 | Hanlim | 2 bottles | — | — | FDA listed | — |
| Auro-Cmc 5 mg/mL 16030-0401-10 | Aurolab | 10 ml | — | — | FDA listed | — |
| Carboxymethylcellulose Sodium Eye Drops 0.5% 5 mg/mL 16030-0501-05 | Aurolab | 5 ml | — | — | FDA listed | — |
| Gentle Eyes Lubricant Eye Drops 5 mg/mL 17312-0430-15 | TRP | 1 bottle | — | — | FDA listed | — |
| Signature Care Lubricant Eye Drops .5 g/100mL 21130-0705-01 | Better | 30 vials | — | — | FDA listed | — |
| Kroger Lubricant Eye .5 g/100mL 30142-0373-33 | The | 30 vials | — | — | FDA listed | — |
| HEB Lubricant Eye Drops .5 g/100mL 37808-0100-01 | HEB | 30 vials | — | — | FDA listed | — |
| Medi-First Lubricant Eye Drops .5 g/100mL 47682-0193-83 | Unifirst | 30 ampules | — | — | FDA listed | — |
| Green Guard Lubricant Eye Drops .5 g/100mL 47682-0194-83 | UniFirst | 30 ampules | — | — | FDA listed | — |
| Equate Lubricant Eye Drops Preservative-Free .5 g/100mL 49035-0245-01 | Wal-Mart | 25 vials | — | — | FDA listed | — |
| Equate Restore Plus Lubricant Eye Drops .5 g/100mL 49035-0389-01 | Walmart, | 70 vials | — | — | FDA listed | — |
| Good Sense Lubricating Plus Lubricant Eye Drops .5 g/100mL 50804-0700-01 | GoodSense | 30 bottles | — | — | FDA listed | — |
| Carboxymethylcellulose Sodium 0.5% 5 mg/mL 51407-0945-30 | Golden | 3 pouches | — | — | Discontinued | — |
| Discount Drug Mart Lubricant Eye Drops 5 mg/mL 53943-0510-01 | Discount | 5 bottles | — | — | FDA listed | — |
| Retaine CMC 5 mg/mL 54799-0460-30 | OCuSOFT | 30 vials | — | — | FDA listed | — |
| Medics Choice Lubricant Eye Drops .5 g/100mL 55651-0030-01 | K.C. | 5 ampules | — | — | FDA listed | — |
| Lubricant Eye Drops 5 mg/mL 55651-0105-05 | KC | 5 bottles | — | — | FDA listed | — |
| Lubricant Eye Drops 5 mg/mL 55651-0510-01 | KC | 5 bottles | — | — | FDA listed | — |
| Publix Moisturizing Relief Eye Drops .5 g/100mL 56062-0789-01 | Publix | 30 vials | — | — | FDA listed | — |
| TheraTears Dry and Tired 5 mg/mL 58790-0013-30 | MEDTECH | 6 pouches | — | — | FDA listed | — |
| Family Care Single Use Lubricant Eye Drop 0.4mL 5ct 5 mg/mL 65923-0575-05 | United | 1 vial | — | — | FDA listed | — |
| Family Care Single Use Lubricant Eye Drop 0.4mL 30ct 5 mg/mL 65923-0576-30 | United | 30 vials | — | — | FDA listed | — |
| Refresh Tears 5 mg/mL 66715-1073-00 | Lil' | 1 bottle | — | — | Discontinued | — |
| Refresh Tears Lubricant 5 mg/mL 67751-0130-01 | Navajo | 3 ml | — | — | Discontinued | — |
| Lubricating Tears 5 mg/mL 69618-0076-55 | Reliable | 1 bottle | — | — | FDA listed | — |
| CVS Lubricant Eye Drops .5 g/100mL 69842-0804-01 | CVS | 70 vials | — | — | FDA listed | — |
| CVS Lubricant Eye Drops 30 ct .5 g/100mL 69842-0993-01 | CVS | 30 vials | — | — | FDA listed | — |
| Lubricant Eye 5 mg/mL 70000-0751-01 | CARDINAL | 30 ampules | — | — | FDA listed | — |
| Lubricant Eye Drops 5 mg/mL 71105-0105-05 | Redicare | 5 bottles | — | — | FDA listed | — |
| TopCare Health Lubricant Eye Drops .5 g/100mL 76162-0089-30 | Topcare | 30 vials | — | — | FDA listed | — |
| Meijer Lubricant Eye Drops .5 g/100mL 79481-0066-01 | Meijer | 30 vials | — | — | FDA listed | — |
| Rain Renewal Eye Drops .5 g/100mL 79662-0001-30 | Rain | 30 bottles | — | — | FDA listed | — |
| Equate Moisturizing Comfort Lubricant Eye Drops .5 g/100mL 79903-0264-05 | Walmart | 1 bottle | — | — | FDA listed | — |
| Focus Tears PF 5 mg/mL 82724-0009-20 | Covalent | 30 vials | — | — | FDA listed | — |
| Eyes Alive Lubricating 5 mg/mL 83291-0200-00 | RIVIERA | 100 ampules | — | — | FDA listed | — |
About this product: other versions of the same ingredient, strength and form are listed above, least expensive first, with FDA equivalence ratings where available.
Where does this data come from?
Equivalents are other NDCs of the same ingredient, form and route from the openFDA NDC Directory, ranked least-expensive-first by NADAC. Therapeutic-equivalence (AB) ratings come from the FDA Orange Book; biologics use the FDA Purple Book for biosimilar & interchangeable status.
- FDA openFDA NDC Directory · synced Oct 1, 2026
- FDA Orange Book · refreshed Sep 3, 2026
- CMS NADAC weekly file
Availability & generic status
🏛️
1997
On the market since
May 1997
📍
2026
Currently FDA-listed
29 years listed
🔒
·
No generic listed yet
brand only
ℹ️No FDA-approved generic found
We did not find an FDA-approved generic match for this exact strength, form and route.
Where does this data come from?
Patents and exclusivity from the FDA Orange Book (small-molecule drugs), refreshed from public FDA data. Generic launch timing is an estimate, not a guarantee.
- FDA Orange Book · refreshed Sep 3, 2026
Inactive Ingredients / Excipients
Inactive ingredients, also called excipients, are components of the drug product other than the active ingredient. They may include fillers, dyes, coatings, preservatives, flavors, or other formulation ingredients.
💡 Tap an ingredient (hover on desktop) to see what it is and why it’s used.
-
UNII R57ZHV85D4
Boric acid is a weak acid derived from boron. In medicines, it typically serves as a buffer to help maintain the product's pH level and may act as a preservative in certain formulations.
-
UNII M4I0D6VV5M
Calcium chloride is a salt compound that acts as a firming agent and source of calcium ions in medications. It's used in formulations to help maintain tablet structure, improve texture, or serve as a buffering agent.
-
UNII 8061YMS4RM
Chlorine dioxide is a disinfectant gas converted to a stable form for use in medicines. It serves as a preservative and antimicrobial agent, helping prevent bacterial and fungal growth in liquid formulations.
-
UNII QTT17582CB
A strong acid used to adjust and maintain the proper pH level in liquid medicines, ensuring stability and preventing breakdown of active ingredients.
-
UNII 02F3473H9O
A mineral salt used in medications as a source of magnesium. It helps bind ingredients together, improve texture, and maintain the product's stability during storage.
-
UNII 660YQ98I10
Potassium chloride is a mineral salt used in medicines as a buffer and to help maintain the proper pH balance and stability of the formulation during storage and use.
-
UNII 91MBZ8H3QO
Sodium borate is an inorganic salt compound used in medicines as a buffer to help maintain a stable pH level, and sometimes as a mild preservative or cleansing agent in topical formulations.
-
UNII T95DR77GMR
Sodium chlorate is a salt compound used in pharmaceutical manufacturing. It may serve as an oxidizing agent in the production process or as a component in certain formulations.
-
UNII 451W47IQ8X
Sodium chloride is common table salt. It's used in medicines as a buffer to maintain proper pH, as a filler to add bulk, or to adjust the osmotic balance in liquid formulations.
-
UNII G538EBV4VF
Sodium chlorite is a white crystalline salt used as a preservative and antimicrobial agent in medications. It helps prevent bacterial and fungal growth to maintain product stability during storage.
-
UNII 55X04QC32I
A strong alkaline chemical used to adjust and maintain the pH balance of liquid medicines. It helps keep the medicine stable and ensures it stays effective during storage.
-
UNII 059QF0KO0R
Water is a liquid solvent that dissolves and mixes ingredients together in liquid medicines, syrups, and injections. It helps distribute the active drug evenly throughout the product.
12 inactive ingredients listed in the exact product block matched to this NDC.
The official label also statesBoric acid; calcium chloride dihydrate; magnesium chloride hexahydrate; potassium chloride; purified water; PURITE ® (stabilized oxychloro complex); sodium borate decahydrate; and sodium chloride. May contain hydrochloric acid and/or sodium hydroxide (to adjust pH).
Label-section wording can be broader than the structured product block and may mention additional formulation ingredients.
Where does this data come from?
Data sourced from official FDA Structured Product Labeling (SPL) via DailyMed —
ingredient classCode="IACT" elements from the exact product block matched by this NDC. Label-section narrative from DailyMed / the openFDA label index is shown separately when available.- FDA label on DailyMed · label index refreshed Oct 1, 2026
- FDA openFDA NDC Directory · synced Oct 1, 2026
Inactive ingredient FAQ
Are inactive ingredients the same for every manufacturer?
No. Inactive ingredients can differ by manufacturer, dosage form, strength, and package / product version.
Why might an inactive ingredient be missing?
Some SPLs do not provide a complete structured inactive-ingredient list, and older or unusual labels may only include the information in narrative text.
Can inactive ingredients matter?
Yes. They can matter for allergies, intolerances, dyes, gluten / lactose concerns, preservatives, and formulation differences — but confirm with a pharmacist or the manufacturer when it’s clinically important.
Manufacturer & labeler
LabelerAllergan, Inc.
FDA applicationM018 (OTC MONOGRAPH DRUG)
Labeler code00023
First marketedMay 1997
Product typeHuman Otc Drug
Portfolio188 products on file
The labeler markets the product; the application holder owns the FDA approval. They’re often the same company but can differ (e.g. a repackager or an authorized generic). A mailing address / phone appears here when the manufacturer includes it in the product’s FDA label (not all do).
Where does this data come from?
Labeler, application holder and registered establishment from the FDA openFDA NDC Directory and Drugs@FDA; address/contact from the product’s FDA label.
- FDA openFDA NDC Directory · synced Oct 1, 2026
- Drugs@FDA
FDA label — Drug Facts FDA SPL
The complete FDA label for this product — the official Drug Facts labeling, verbatim, section by section. Jump with a chip, search within the label, or expand everything.
🎯 Indications and Usage
⏱️ Dosage and Administration
⚠️ Warnings
🧪 Active Ingredient
🧪 Inactive Ingredients
🎯 Purpose
📄 Stop Use and Ask a Doctor If
📄 Keep Out of Reach of Children
📄 Other Information
📄 Questions or Comments
📄 Package Label / Principal Display Panel
🎯 Indications and Usage ▾
Uses For the temporary relief of burning, irritation, and discomfort due to dryness of the eye or exposure to wind or sun. May be used as a protectant against further irritation.
⏱️ Dosage and Administration ▾
Directions Instill 1 or 2 drops in the affected eye(s) as needed.
⚠️ Warnings ▾
Warnings For external use only. To avoid contamination, do not touch tip of container to any surface. Replace cap after using.
If solution changes color or becomes cloudy, do not use. Stop use and ask a doctor if you experience eye pain, changes in vision, continued redness or irritation of the eye, or if the condition worsens or persists for more than 72 hours. Keep out of reach of children.
If swallowed, get medical help or contact a Poison Control Center right away.
🧪 Active Ingredient ▾
Active ingredient Carboxymethylcellulose sodium 0.5%
🧪 Inactive Ingredients ▾
Inactive ingredients Boric acid; calcium chloride dihydrate; magnesium chloride hexahydrate; potassium chloride; purified water; PURITE ® (stabilized oxychloro complex); sodium borate decahydrate; and sodium chloride. May contain hydrochloric acid and/or sodium hydroxide (to adjust pH).
🎯 Purpose ▾
Purpose Eye lubricant
📄 Stop Use and Ask a Doctor If ▾
Stop use and ask a doctor if you experience eye pain, changes in vision, continued redness or irritation of the eye, or if the condition worsens or persists for more than 72 hours.
📄 Keep Out of Reach of Children ▾
Keep out of reach of children. If swallowed, get medical help or contact a Poison Control Center right away.
📄 Other Information ▾
Other information Use only if tape seals on top and bottom flaps are intact. Use before expiration date marked on container. Discard 90 days after opening. Store at 59°-77°F (15°-25°C). RETAIN THIS CARTON FOR FUTURE REFERENCE.
📄 Questions or Comments ▾
Questions or comments? 1.800. 6 78 . 1605 refreshbrand.com v1.0DFL0798
📄 Package Label / Principal Display Panel ▾
PRINCIPAL DISPLAY PANEL Refresh Tears ® Lubricant Eye Drops ORIGINAL STRENGTH Moisturizing Relief for Dry, Irritated Eyes 0.5 fl oz (15 mL) Sterile Refresh Tears® Lubricant Eye Drops ORIGINAL STRENGTH Moisturizing Relief for Dry, Irritated Eyes 0.5 fl oz (15 mL) Sterile
PRINCIPAL DISPLAY PANEL Multi-Pack More bottles for more places Refresh Tears ® Lubricant Eye Drops ORIGINAL STRENGTH Moisturizing Relief for Dry, Irritated Eyes 4 bottles 0.5 fl oz (15 mL) each plus 1 bottle 0.17 fl oz (5 mL) Sterile Multi-Pack More bottles for more places Refresh Tears® Lubricant Eye Drops ORIGINAL STRENGTH Moisturizing Relief for Dry, Irritated Eyes 4 bottles 0.5 fl oz (15 mL) each plus 1 bottle 0.17 fl oz (5 mL) Sterile
No label section mentions that — try another word, or open the full label on DailyMed below.
Source: FDA Structured Product Labeling, mirrored from DailyMed / openFDA.
Prefer the government’s original formatting? View this label on DailyMed ↗
Medicaid utilization by pack size
Medicaid (SDUD) totals over the four most recent reported quarters for every package size of this drug — handy when a specific package (e.g. a starter/titration pack) carries little or no Medicaid volume on its own.
Drug total (last 4 qtrs): 715,577 Rx · 11,823,743 units · $12,197,683 gross reimbursed
Tap a pack size to open its page. Source: CMS State Drug Utilization Data, last 4 quarters.
Reported adverse events (FAERS)
Read carefully: FAERS reports are voluntary and unverified. Counts are not incidence, do not establish causation, are subject to reporting bias, and cannot be used to compare one drug to another. Shown for signal context only. Reports for Refresh Tears (this brand).
Top reported reactions
Age at onset
Reporter sex
Male · 23%
Female · 76%
Unknown · 0%
Serious outcomes
Reports over time (by year) — tap or hover for the count & year
Most recent year is provisional (FAERS lags ~3 months).
Where does this data come from?
Adverse-event reports from the FDA Adverse Event Reporting System (FAERS) via openFDA. FAERS reports are voluntary and unverified — counts are not incidence and don’t establish causation.
About this NDC listing & data coverage
Over-the-counter (OTC) product
No longer marketed (per FDA listing data)
What data is (and isn’t) available for this NDC — tap to expand
| NDC identity (package / product / labeler codes) | ✓ Available |
| Labeler | ✓ Available |
| Product & package description | ✓ Available |
| Marketing category & status | ✓ Available |
| Active ingredient / dosage form / route | ✓ Available |
| FDA label (SPL via DailyMed) | ✓ Available |
| Package photos | ✓ Available |
| Inactive ingredients (structured) | ✓ Available |
| NADAC pharmacy acquisition price (CMS) | — Not published for this NDC CMS publishes NADAC only for NDCs reported in its retail-pharmacy survey. |
| Orange Book / therapeutic-equivalence data | — Not published for this NDC Applies only to products approved under an NDA/ANDA; many listings are out of scope. |
| HCPCS J-code billing crosswalk | — Not published for this NDC Most self-administered / retail products have no J-code — that is normal. |
| Medicaid utilization (CMS SDUD) | — Not published for this NDC CMS reports utilization only for NDCs with Medicaid claims above its privacy threshold. |
“Not published” reflects what the public FDA / CMS / NLM sources provide for this exact package code — it is a property of the data feeds, not a judgment about the product.
Questions about this listing
Is this NDC FDA-approved?
An NDC listing does not by itself establish FDA approval — the NDC Directory records that a product is listed with FDA, not that it was reviewed and approved. This listing's marketing category is "Otc Monograph Drug". Products approved under an application carry an NDA, ANDA, or BLA number.
Why is there no price listed?
The pricing shown on our NDC pages comes from CMS NADAC, a voluntary survey of retail community pharmacy invoices. CMS does not publish a NADAC for every NDC — packages outside the retail survey (institutional and hospital products, bulk packages, discontinued items, and many OTC items) may never receive one. A missing price reflects the survey's scope, not this product's actual cost, and does not mean the product is free or unavailable.
What does the discontinued status mean for this NDC?
The labeler reported a marketing end date (or the listing was delisted), so this specific package is no longer actively marketed. Remaining stock may still be dispensed for a time, and the NDC stays valid for historical records and claims — but data feeds (pricing, labeling) typically stop updating for it. Other package sizes or other manufacturers' versions of the same medication may still be marketed — see the equivalents section where available.
Is the NDC printed on the package the same as the 11-digit billing NDC?
Yes, they identify this exact package in different formats. The form printed on the packaging and shown on DailyMed is the one the FDA registered. Insurance claims use a fixed 11-digit 5-4-2 format, so the short segment is padded with a leading zero and the dashes are dropped. The Identity section at the top of this page lists each form of this code.
Does this product come in other package sizes?
Yes — the FDA directory lists 4 other package presentations of this same product, including 1 bottle (00023-0798-03), 1 bottle (00023-0798-04), 1 bottle (00023-0798-15). Each has its own NDC and its own page — see the package list near the top of this page.
Who lists this product with the FDA?
Allergan, Inc. is the labeler of record for this NDC — the company under whose FDA-assigned code the package is listed. The labeler may be the manufacturer itself or a distributor marketing the product under its own code.
Do I need a prescription for this product?
This NDC is listed with FDA as an over-the-counter product, so it does not require a prescription. Follow the package directions, and ask your pharmacist if you are unsure whether it is right for you.
This page identifies an FDA-listed package (the NDC) and reports public regulatory and pricing data about the listing. It is reference information, not a medical recommendation — talk to your pharmacist or prescriber about your own medication.
Where does this data come from?
Listing facts (marketing category, packager status, marketing dates) from the FDA openFDA NDC Directory; label availability from DailyMed; pricing coverage from CMS NADAC; equivalence scope from the FDA Orange Book.
For educational and professional reference only — not medical advice. Pricing reflects published
NADAC and CMS ASP (free public data) and may differ from your acquisition cost; always verify before billing or dispensing.