Systane Balance propylene glycol .06 mg/mL Emulsion — NDC 0065-1433-07 (Billing 00065-1433-07)
This is a package of Systane Balance propylene glycol .06 mg/mL Emulsion from Alcon Laboratories, Inc., marketed since Jun 2010 and currently FDA-listed; retail pharmacies pay about $1.00 per mL (NADAC).
Other active recalls for Propylene Glycol (different manufacturers) — 1 · tap to view
Past resolved recalls for this product (1)
Identity & classification
Regulatory identifiers FDA, NLM and CMS codes for this package
Drug-database identifiers Medi-Span GPI and First Databank GCN / HICL / AHFS classification
- GSN (GCN sequence number): 066795
- GCN: 29189
- GPI-14 (Medi-Span): 86200060002015
- HICL (First Databank): 003808
- AHFS class code: 52:92.00.00
Where does this data come from?
- FDA openFDA NDC Directory · synced Oct 1, 2026
- FDA label on DailyMed · label index refreshed Oct 1, 2026
- RxNorm (NLM RxNav) · catalog refreshed Oct 1, 2026
- Medi-Span GPI (licensed)
- First Databank (licensed) · refreshed Oct 1, 2026
Clinical
Systane Balance is an over-the-counter eye emulsion containing propylene glycol, an ingredient that is typically used to lubricate and moisturize the surface of the eye. This product is applied directly to the eye and falls under the FDA's OTC monograph category for lubricating eye drops, meaning it is marketed under a general set of rules for this class of product rather than as an individually approved medication. Propylene glycol is a common component in artificial tear formulations meant to help manage dry eye discomfort.
Patient education
Supplement & herbal interactions
Where does this data come from?
- MedlinePlus (NLM) · refreshed Oct 1, 2026
- FDA label on DailyMed · label index refreshed Oct 1, 2026
Ask a licensed pharmacist directly — free, answered by our team.
Pricing
A drug doesn't have one price. Each row is a different public payment system, and none is what you'd pay at the counter — that depends on your insurance. The ⓘ on each row explains what it measures.
| Price system | Per mL | Per package |
|---|---|---|
| Retail pharmacies payNADAC · weekly | $1.002 | $20.03 / 20 ml |
| Medicaid paysCMS SDUD · 12 mo | $1.34 | $26.71 / 20 ml |
| Medicare drug plans payPart D · quarterly | No Part D plan price is available for this NDC in our data. | |
Where does this data come from?
- CMS NADAC weekly file · file of Sep 30, 2026
- CMS ASP pricing files · refreshed Sep 20, 2026
- CMS Medicaid State Drug Utilization Data · through Q1 2026
- CMS Part D plan pricing files · refreshed Sep 24, 2026
- VA National Acquisition Center price file
Packaging — all sizes for this product
| Package NDC | Description | Per unit | Per pack | Marketing start | Marketing end | Status |
|---|---|---|---|---|---|---|
| 00065-1433-02 0065-1433-02 Main listing | 1 BOTTLE, DROPPER in 1 CARTON / 10 mL in 1 BOTTLE, DROPPER | $1.17 / mL | $11.68 | 2010-06-25 | — | Active |
| 00065-1433-07 You're viewing this | 2 BOTTLE, DROPPER in 1 CARTON / 10 mL in 1 BOTTLE, DROPPER | $1.00 / mL | $20.03 | 2010-06-25 | — | Active |
| 00065-1433-11 0065-1433-11 | 1 BOTTLE, DROPPER in 1 CARTON / 1.5 mL in 1 BOTTLE, DROPPER | — | — | 2010-06-25 | — | Active |
This pack has the lowest per-mL cost of the 2 priced pack sizes ($1.00 NADAC).
This pack accounts for about 7.6% of this product's recent Medicaid fills; most go to a different pack size. See all packs ↓
Pack size FAQ
What quantity is in this package?
What NDC number is used to bill for this package of Systane Balance propylene glycol .06 mg/mL Emulsion?
Prices are the latest CMS NADAC pharmacy acquisition cost per NDC; per-pack figures are per-unit × pack quantity, shown only when the pack is denominated in the same measure NADAC prices.
Therapeutic equivalents
| Product | Labeler | Pack | NADAC/unit | TE | Status | Price vs. this |
|---|---|---|---|---|---|---|
| Leader Restorative Formula Lubricant Eye Drops .6 g/100mL 70000-0013-01 | Cardinal | 1 bottle | $0.214 | — | Availability likely | save 79% |
| Systane Balance .06 mg/mLthis 00065-1433-07 | Alcon | 2 bottles | $1.002 | — | Availability likely | — |
| Systane COMPLETE PF .06 mg/mL 00065-1509-28 | Alcon | 1 bottle | $1.347 | — | Availability likely | +34% |
| Systane COMPLETE .06 mg/mL 00065-0481-01 | Alcon | 1 bottle | — | — | FDA listed | — |
| Systane COMPLETE PF .06 mg/mL 00065-1530-01 | Alcon | 5 vials | — | — | FDA listed | — |
| OneDrop .6 g/100mL 57619-0306-01 | LABORATORIOS | 1 bottle | — | — | FDA listed | — |
Where does this data come from?
- FDA openFDA NDC Directory · synced Oct 1, 2026
- FDA Orange Book · refreshed Sep 3, 2026
- CMS NADAC weekly file · file of Sep 30, 2026
Availability & generic status
We did not find an FDA-approved generic match for this exact strength, form and route.
Where does this data come from?
- FDA Orange Book · refreshed Sep 3, 2026
Inactive Ingredients / Excipients
Inactive ingredients, also called excipients, are components of the drug product other than the active ingredient. They may include fillers, dyes, coatings, preservatives, flavors, or other formulation ingredients.
💡 Tap an ingredient (hover on desktop) to see what it is and why it’s used.
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UNII R57ZHV85D4
Boric acid is a weak acid derived from boron. In medicines, it typically serves as a buffer to help maintain the product's pH level and may act as a preservative in certain formulations.
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UNII BI71WT9P3R
A synthetic phospholipid (fat-like molecule) used as a surfactant and emulsifier in medicines. It helps stabilize and mix oil and water-based ingredients, and is commonly used in inhalation products and injectable formulations.
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UNII 7FLD91C86K
Edetate disodium is a chemical compound that binds and removes certain metal ions. In medicines, it acts as a preservative and stabilizer by preventing metals like calcium from interfering with the product's shelf life and consistency.
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UNII E89I1637KE
Guar gum is a natural thickener made from guar bean seeds. It's used in medicines as a binder and thickening agent to hold ingredients together and create the right texture and consistency.
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UNII QTT17582CB
A strong acid used to adjust and maintain the proper pH level in liquid medicines, ensuring stability and preventing breakdown of active ingredients.
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UNII T5L8T28FGP
Mineral oil is a clear, odorless liquid derived from crude oil. It acts as a lubricant and emollient in medications, helping pills slide smoothly during manufacturing and aiding moisture retention in topical products.
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UNII 6716Z5YR3G
A synthetic polymer compound used as an antimicrobial preservative and stabilizer in pharmaceutical formulations. It helps prevent microbial growth and maintain product stability during storage.
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UNII 13A4J4NH9I
A synthetic emulsifier derived from stearic acid and polyethylene glycol. It helps mix oil and water-based ingredients together in liquid medicines and creams to create a smooth, uniform product.
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UNII 55X04QC32I
A strong alkaline chemical used to adjust and maintain the pH balance of liquid medicines. It helps keep the medicine stable and ensures it stays effective during storage.
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UNII 6LUM696811
A waxy substance derived from sorbitol and stearic acid. It acts as an emulsifier and stabilizer to help mix oil and water components evenly throughout the medicine and prevent separation.
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UNII 506T60A25R
Sorbitol is a natural sugar alcohol derived from glucose. It serves as a sweetener, humectant, and bulking agent in medications to improve taste and help maintain moisture in the product.
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UNII 059QF0KO0R
Water is a liquid solvent that dissolves and mixes ingredients together in liquid medicines, syrups, and injections. It helps distribute the active drug evenly throughout the product.
12 inactive ingredients listed in the exact product block matched to this NDC.
Label-section wording can be broader than the structured product block and may mention additional formulation ingredients.
Where does this data come from?
ingredient classCode="IACT" elements from the exact product block matched by this NDC. Label-section narrative from DailyMed / the openFDA label index is shown separately when available.- FDA label on DailyMed · label index refreshed Oct 1, 2026
- FDA openFDA NDC Directory · synced Oct 1, 2026
Inactive ingredient FAQ
Are inactive ingredients the same for every manufacturer?
Why might an inactive ingredient be missing?
Can inactive ingredients matter?
Manufacturer & labeler
Where does this data come from?
- FDA openFDA NDC Directory · synced Oct 1, 2026
- Drugs@FDA
FDA label — Drug Facts FDA SPL
🎯 Indications and Usage ▾
Uses for the temporary relief of burning and irritation due to dryness of the eye for use as a lubricant to prevent further irritation or to relive dryness of the eye
⏱️ Dosage and Administration ▾
Directions shake well before using put 1 or 2 drops in the affected eye(s) as needed
⚠️ Warnings ▾
Warnings For external use only Do not use if this product changes color if you are sensitive to any ingredient in this product When using this product do not touch tip of container to any surface to avoid contamination replace cap after each use Stop use and ask a doctor if you experience any of the following: eye pain changes in vision continued redness or irritation of the eye condition worsens or persists for more than 72 hours Keep out of reach of children. If swallowed, get medical help or contact a Poison Control Center right away.
🧪 Active Ingredient ▾
Active Ingredient Purpose Propylene Glycol 0.6% Lubricant
🧪 Inactive Ingredients ▾
Inactive ingredients: boric acid, dimyristoyl phosphatidylglycerol, edetate disodium, hydroxypropyl guar, mineral oil, polyoxyl 40 stearate, POLYQUAD ® (polyquaternium-1) 0.001% preservative, sorbitan tristearate, sorbitol and purified water. May contain hydrochloric acid and/or sodium hydroxide to adjust pH.
🎯 Purpose ▾
Active Ingredient Purpose Propylene Glycol 0.6% Lubricant
📄 Do Not Use ▾
Do not use if this product changes color if you are sensitive to any ingredient in this product
📄 When Using This Product ▾
When using this product do not touch tip of container to any surface to avoid contamination replace cap after each use
📄 Stop Use and Ask a Doctor If ▾
Stop use and ask a doctor if you experience any of the following: eye pain changes in vision continued redness or irritation of the eye condition worsens or persists for more than 72 hours
📄 Keep Out of Reach of Children ▾
Keep out of reach of children. If swallowed, get medical help or contact a Poison Control Center right away.
📄 Questions or Comments ▾
Questions: In the U.S. call 1-800-757-9195 [email protected] www.systane.com
📄 Package Label / Principal Display Panel ▾
PRINCIPAL DISPLAY PANEL Systane ® LUBRICANT EYE DROPS BALANCE Restoring Dry Eye Relief Locks in moisture Tear evaporation protection Clinically proven DOCTOR RECOMMENDED #1 BRAND 1 Alcon STERILE 10 mL (1/3 FL OZ) LOT: EXP.: SIDE PANEL TAMPER EVIDENT: For your protection, this bottle has an imprinted seal around the neck. Do not use if seal is damaged or missing at time of purchase. www.alconpatents.com Made in USA from domestic and imported materials Systane ® BALANCE Lubricant Eye Drops restores the natural tear’s lipid layer to lock in moisture and protect against tear evaporation.
ACTUAL SIZE Alcon Alcon Laboratories, Inc. Fort Worth, TX 76134 USA 1 Based on a survey of eye care professionals. Data on file.
300048644-0521
PRINCIPAL DISPLAY PANEL TWIN PACK Systane ® LUBRICANT EYE DROPS BALANCE Restoring Dry Eye Relief Locks in moisture Tear evaporation protection Clinically proven DOCTOR RECOMMENDED #1 BRAND 1 Alcon STERILE Two 10 mL (1/3 FL OZ) Bottles LOT: EXP.: SIDE PANEL TAMPER EVIDENT: For your protection, this bottle has an imprinted seal around the neck. Do not use if seal is damaged or missing at time of purchase. www.alconpatents.com Made in USA from domestic and imported materials Systane ® BALANCE Lubricant Eye Drops restores the natural tear’s lipid layer to lock in moisture and protect against tear evaporation.
ACTUAL SIZE Alcon Alcon Laboratories, Inc. Fort Worth, TX 76134 USA 1 Based on a survey of eye care professionals. Data on file.
300037158-0420 Systane ® LUBRICANT EYE DROPS BALANCE Restoring Dry Eye Relief Lipid Rich Formula Tear evaporation protection DOCTOR RECOMMENDED #1 BRANDS 1 Alcon STERILE 10 mL (1/3 fl oz) LOT: EXP.: SIDE PANEL TAMPER EVIDENT: For your protection, this bottle has an imprinted seal around the neck. Do not use if seal is damaged or missing at time of purchase. www.alconpatents.com Country of Origin: Singapore Systane ® BALANCE Lubricant Eye Drops restores the natural tear’s lipid layer to lock in moisture and protect against tear evaporation.
ACTUAL SIZE Alcon Alcon Laboratories, Inc. Fort Worth, TX 76134 USA 1 Based on a survey of eye care professionals. Data on file.
300072016-0525
PRINCIPAL DISPLAY PANEL Systane ® LUBRICANT EYE DROPS BALANCE Restoring Dry Eye Relief STERILE 10 mL (1/3 FL OZ) INGREDIENTS: Active: Propylene Glycol 0.6%. Inactives: Boric acid, dimyristoyl phosphatidylglycerol, edetate disodium, hydroxypropyl guar, mineral oil, polyoxyl 40 stearate, POLYQUAD ® (polyquaternium-1) 0.001% preservative, sorbitan tristearate, sorbitol and purified water. May contain hydrochloric acid and/or sodium hydroxide to adjust pH.
Store at room temperature. FOR EXTERNAL USE ONLY USES : See carton for USES. WARNINGS : See carton for WARNINGS.
DIRECTIONS : Shake well and put 1 or 2 drops in the affected eye(s) as needed. Alcon Alcon Laboratories, Inc. Fort Worth, TX 76134 USA 300060319-0223