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Naproxen Sodium 220 mg Tablet, 80-count — NDC 00363-7510-80 package photo
Label image from the product's FDA listing (DailyMed) — may show a different pack size or an older label revision.

Naproxen Sodium 220 mg Tablet, 80-count — NDC 0363-7510-80 (Billing 00363-7510-80)

by Walgreens · 1 BOTTLE, PLASTIC in 1 BOX / 80 TABLET in 1 BOTTLE, PLASTIC

This is a package of 80 tablets of Naproxen Sodium 220 mg Tablet from Walgreens, marketed since Jan 2020 and currently FDA-listed.

NDC 00363-7510-80
🏷️ FDA NDC (as labeled) 0363-7510-80 billing pads the labeler segment with a zero
This package
Contains80-count Pack sizes4 compare ↓
Product page 00363-7510-20 Also comes in: 20 tablets 0363-7510-20 40 tablets 0363-7510-40 50 tablets 0363-7510-50
OTC Generic On market Non-controlled ⇄ Compare with another NDC
🗂️ FDA directory synced Oct 1, 2026 · this listing last changed Jul 24, 2026 · sources: openFDA · FDA label (DailyMed) · FDA Orange & Purple Book · First Databank · CMS NADAC, ASP, Medicare & Medicaid · RxNorm
📋 All sources & update times →

This page is curated, coded, and maintained by

Compiled from public FDA, CMS, DailyMed, NADAC, and related drug data sources. Editorial policy

NDC database record

One package, one record: these facts belong to NDC 0363-7510-80 alone.

Record
FDA NDC Directory package listing · Human OTC drug
Code segments
0363 labeler · 7510 product · 80 package
Package marketed since
Jan 31, 2020
Sample package
No — commercial package
Listing certified through
Dec 31, 2026
Barcode (UPC)
0311917031033
FDA record last changed
Jul 24, 2026
⚠️
Other active recalls for Naproxen Sodium (different manufacturers) — 2 · tap to view
These affect other manufacturers’ products for the same ingredient — not necessarily the exact NDC on this page.
Class II · Mar 13, 2025 — CGMP Deviations (Glenmark Pharmaceuticals Inc., USA) · FDA recall D-0346-2025
Class II · Nov 7, 2023 — Labeling: Label Mix-Up-Indomethacin bottles may be labeled as Naproxen (Glenmark Pharmaceuticals Inc., USA) · FDA recall D-0124-2024
Each entry is an official FDA enforcement report — look up any recall number in the FDA recall database ↗

Identity & classification

Regulatory identifiers FDA, NLM and CMS codes for this package

FDA NDC (as labeled) 0363-7510-80
Product NDC 0363-7510
11-digit billing NDC 00363751080
UNII 9TN87S3A3C
UPC 0311917031033
Application # ANDA202807
SPL Set ID a380cace-43dc-4b9c-84d3-0b38241d9d2e
Established class (EPC) Anti-Inflammatory Agents; Nonsteroidal Anti-inflammatory Drug
Mechanism of action Cyclooxygenase Inhibitors
Chemical class Non-Steroidal
DEA schedule Non-controlled
Marketing category ANDA
Marketing status On market
FDA listing status Listed (active directory)
Marketing start 2020-01-31
Route ORAL
Dosage form TABLET
Substance NAPROXEN SODIUM
Why two NDCs? The FDA registers this code as 0363-7510-80 — a 4-4-2 layout, and that's what's printed on the package and shown on DailyMed. For insurance claims, every NDC is standardized to a uniform 11-digit 5-4-2 format by adding a zero to the labeler segment → 00363-7510-80. Same drug, same package — only the format differs.
Where does this data come from?
Identifiers from the FDA openFDA NDC Directory and Structured Product Labeling; RxCUI from RxNorm (NLM); GPI from Medi-Span; GCN / HIC / AHFS / legend from First Databank.

Clinical

📗 Our plain-language guide HelloPharmacist
  • It relieves pain, inflammation and fever. Prescription versions treat arthritis, tendonitis, bursitis, acute gout and painful periods. Over-the-counter versions handle minor aches...
  • Take it by mouth with a full glass of water. Over-the-counter products are taken every 8 to 12 hours while symptoms last, and you should use the smallest dose that works. For presc...
  • Headache, indigestion, heartburn, nausea and swelling are common. Call your doctor if you have black stools, vomit blood, a rash, yellow skin or eyes, or chest pain.
  • Usually not. Combining naproxen with other NSAIDs or aspirin raises bleeding risk with little added benefit. Naproxen can also interfere with low-dose aspirin taken for your heart,...
📖 Read our full Naproxen guide →
1
Nutrient depletion considerations

Naproxen Sodium may be associated with lower levels of 1 nutrient — worth a chat with your pharmacist, not a cause for alarm.

🧪 Full Naproxen Sodium nutrient depletion report →
An association is not a deficiency. Educational only — don't start or stop anything without professional guidance.
Where does this data come from?
Plain-language summary from MedlinePlus (U.S. National Library of Medicine); supplement & herbal interactions and nutrient depletion data from the Natural Medicines database; our full guide is HelloPharmacist editorial content.

Pricing

A drug doesn't have one price. Each row is a different public payment system, and none is what you'd pay at the counter — that depends on your insurance. The ⓘ on each row explains what it measures.

Price systemPer eachPer package
Retail pharmacies payNADAC · weekly Not in the retail survey — common for institutional, discontinued, or low-volume packs.
Medicaid paysCMS SDUD · 12 mo No recent Medicaid claims on file for this NDC — rare and low-volume NDCs are suppressed in the public data.
Medicare drug plans payPart D · quarterly No Part D plan price is available for this NDC in our data.
ℹ️
No price is published for this exact package yet. CMS surveys NADAC per package size, so a different pack of the same drug often has one.
Try another pack size: 20 tablets 40 tablets 50 tablets
Where does this data come from?
NADAC (National Average Drug Acquisition Cost) is the CMS weekly pharmacy-acquisition-cost survey — what pharmacies pay. ASP (Average Sales Price) is the CMS Medicare Part B drug-payment file, published quarterly. Medicaid pays is computed by us from CMS State Drug Utilization Data (total reimbursed ÷ units, trailing 12 months) — gross of rebates and inclusive of dispensing fees, so it reflects what Medicaid paid, not an acquisition cost. Medicare drug plans pay is the median negotiated point-of-sale unit cost across plans listing this NDC in the CMS quarterly Prescription Drug Plan pricing files, before rebates. The VA pays is the federal contract price (FSS, and the statutory Big 4 ceiling where listed) from the VA National Acquisition Center pharmaceutical price file. All are free public government data; each measures a different payer, so the figures are not directly comparable.

Packaging — all sizes for this product

Package NDCDescription Marketing startMarketing endStatus
00363-7510-20 0363-7510-20 Main listing 1 BOTTLE, PLASTIC in 1 BOX / 20 TABLET in 1 BOTTLE, PLASTIC 2020-01-31 — Active
00363-7510-40 0363-7510-40 1 BOTTLE, PLASTIC in 1 BOX / 40 TABLET in 1 BOTTLE, PLASTIC 2020-01-31 — Active
00363-7510-50 0363-7510-50 1 BOTTLE, PLASTIC in 1 BOX / 50 TABLET in 1 BOTTLE, PLASTIC 2020-01-31 — Active
00363-7510-80 You're viewing this 1 BOTTLE, PLASTIC in 1 BOX / 80 TABLET in 1 BOTTLE, PLASTIC 2020-01-31 — Active

Pack size FAQ

What quantity is in this package?
This is a 80-count package — 1 bottle, plastic in 1 box / 80 tablet in 1 bottle, plastic.
How does this package differ from NDC 00363-7510-20?
Both are Naproxen Sodium 220 mg Tablet — the drug itself is identical. This page's package is the 80-count one, while NDC 00363-7510-20 is the 20 tablets package.
What NDC number is used to bill for this package of Naproxen Sodium 220 mg Tablet?
Use the 11-digit billing form listed in the identifiers section of this page. Pharmacy and medical claims use the 11-digit form; the FDA label may print a shorter form of the same code.

Therapeutic equivalents

ProductLabelerPackNADAC/unitTEStatusPrice vs. this
Leader All Day Pain Relief 220 mg 70000-0171-01 Cardinal 100 tablets $0.059 — Discontinued —
Naproxen Sodium 220 mg 45802-0490-71 Padagis 50 tablets $0.059 — Discontinued —
Rugby All Day Relief 220 mg 00536-1093-01 Rugby 100 tablets $0.063 — Discontinued —
Naproxen Sodium 220 mg 63868-0465-01 Chain 100 tablets $0.065 — FDA listed —
rugby all day relief 220 mg 00536-1094-01 Rugby 100 tablets $0.065 — Discontinued —
Naproxen sodium 220 mg 69230-0329-01 Camber 100 tablets $0.067 — Availability likely —
foster and thrive all day pain relief 220 mg 70677-1137-01 Strategic 50 tablets $0.067 — Availability likely —
Good Sense Naproxen Sodium 220 mg 00113-0901-62 L. 24 tablets $0.067 — Availability likely —
Naproxen 220 mg 46122-0564-71 Amerisource 50 tablets $0.067 — Availability likely —
Good Sense Naproxen Sodium 220 mg 00113-4368-62 L. 24 tablets $0.067 — Availability likely —
Naproxen 220 mg 46122-0562-71 Amerisource 50 tablets $0.067 — Availability likely —
Leader All Day Pain Relief 220 mg 70000-0201-02 Cardinal 50 tablets $0.067 — Availability likely —
Naproxen Sodium 220 mgthis 00363-7510-80 Walgreens 80 tablets — — FDA listed —
Flanax Pain Reliever/Fever reducer 220 mg 27854-0505-01 Belmora 24 tablets — — FDA listed —
Flanax Pain Reliever/Fever Reducer 220 mg 27854-0700-01 Belmora 24 tablets — — FDA listed —
Ana-Dent PAIN RELIEF 220 mg 27854-0701-01 Belmora 24 tablets — — FDA listed —
Naproxen Sodium 220 mg 41226-0609-05 Kroger 50 tablets — — FDA listed —
Naproxen Sodium 220 mg 49483-0609-00 TIME 6500 tablets — — FDA listed —
All Day Pain Relief 220 mg 59726-0169-15 P 15 tablets — — Discontinued —
Naproxen Sodium 220 mg 63187-0596-24 Proficient 24 tablets — — FDA listed —
Good Sense Naproxen Sodium 220 mg 63187-0794-20 Proficient 20 tablets — — FDA listed —
betr headache pain relief 220 mg 80267-0001-71 Live 50 tablets — — FDA listed —
Bayer Aleve 220 mg 00924-6000-00 Acme 1 tablet — — FDA listed —
Pain Relief 220 mg 21130-0608-05 BETTER 50 tablets — — FDA listed —
Naproxen Sodium 220 mg 21130-0690-05 BETTER 50 tablets — — FDA listed —
All Day Pain Relief 220 mg 37808-0068-24 H 24 tablets — — FDA listed —
Belmora Flanax 220 mg 47682-0037-50 Unifirst 1 tablet — — FDA listed —
Naproxen Sodium 220 mg 49483-0608-00 TIME 6500 tablets — — FDA listed —
Naproxen Sodium 220 mg 50090-0685-01 A-S 10 tablets — — FDA listed —
Naproxen Sodium (NSAID) Fever Reducer/ Pain Reliever 220 mg 53746-0191-05 Amneal 500 tablets — — FDA listed —
Naproxen Sodium (NSAID) Fever Reducer/ Pain Reliever 220 mg 53746-0192-05 Amneal 500 tablets — — FDA listed —
naproxen sodium 220 mg 59779-0914-75 CVS 90 tablets — — FDA listed —
Naproxen Sodium 220 mg 62207-0327-41 Granules 24 tablets — — FDA listed —
Naproxen Sodium 220 mg 62207-0328-41 Granules 24 tablets — — FDA listed —
Naproxen Sodium 220 mg 62207-0728-24 Granules 24 tablets — — FDA listed —
Naproxen Sodium 220 mg 62207-0729-24 Granules 24 tablets — — FDA listed —
Naproxen Sodium 220 mg 62207-0761-42 Granules 50 tablets — — FDA listed —
Naproxen Sodium 220 mg 62207-0762-42 Granules 50 tablets — — FDA listed —
Flanax Pain Reliever/Fever Reducer 220 mg 67751-0125-01 Navajo 2 tablets — — FDA listed —
Aleve 220 mg 67751-0144-03 Navajo 1 tablet — — FDA listed —
Proxen Np 660 220 mg 69729-0123-12 OPMX 12 tablets — — FDA listed —
Naproxen 220 mg 71205-0595-30 Proficient 30 tablets — — FDA listed —
All Day Back and Muscle Pain Relief 220 mg 79903-0609-09 Walmart 90 tablets — — FDA listed —
Back and Muscle Pain 220 mg 11822-4170-02 Rite 100 tablets — — Discontinued —
Topcare All Day Pain Relief 220 mg 36800-0490-62 Topco 24 tablets — — FDA listed —
CareOne Naproxen Sodium 220 mg 41520-0507-48 American 90 tablets — — Discontinued —
Medique Mediproxen 220 mg 50090-2388-00 A-S 1 tablet — — FDA listed —
Naproxen Sodium 220 mg 50844-0417-14 L.N.K. 500 tablets — — FDA listed —
Back and Muscle Pain 220 mg 51316-0817-08 CVS 24 tablets — — FDA listed —
Naproxen Sodium 220mg 220 mg 53329-0688-30 Medline 100 tablets — — Discontinued —
Naproxen 220 mg 53943-0145-02 DISCOUNT 50 tablets — — FDA listed —
dg health naproxen sodium 220 mg 55910-0500-71 Dolgencorp 50 tablets — — Discontinued —
Aleve Caplets - Easy Open Arthritis Cap 220 mg 00280-6050-01 Bayer 100 tablets — — FDA listed —
Aleve 220 mg 66715-6502-02 Lil' 2 tablets — — FDA listed —
Naproxen 220 mg 68071-5039-01 NuCare 21 tablets — — FDA listed —
Naproxen Sodium 220 mg 69842-0811-62 CVS 24 tablets — — FDA listed —
Naproxen Sodium 220 mg 79903-0231-50 WALMART 50 tablets — — FDA listed —
All Day Pain Relief 220 mg 79903-0389-50 Walmart 50 tablets — — FDA listed —
Flanax 220 mg 27854-0160-00 Belmora 100 tablets — — Discontinued —
AnaDent 220 mg 27854-0170-01 Belmora 24 tablets — — FDA listed —
Belmora Flanax 220 mg 27854-0555-01 Belmora 24 tablets — — FDA listed —
Naproxen Sodium 220 mg 30142-0954-10 Kroger 100 tablets — — FDA listed —
TopCare All Day Pain Relief 220 mg 36800-0368-62 Topco 24 tablets — — FDA listed —
Naproxen Sodium Caplets 220 mg 43598-0058-29 Dr 200 tablets — — FDA listed —
Naproxen Sodium Back and Muscle Pain 220 mg 43598-0074-01 Dr.Reddy's 100 tablets — — FDA listed —
Naproxen Sodium 220 mg 51316-0761-20 CVS 200 tablets — — FDA listed —
DG Health Naproxen Sodium 220 mg 55910-0490-62 Dolgencorp 24 tablets — — FDA listed —
Naproxen Sodium BACK AND MUSCLE PAIN 220 mg 58602-0739-07 Aurohealth 24 tablets — — FDA listed —
Aleve Easy Open Arthritis Cap 220 mg 00280-6060-20 Bayer 200 tablets — — FDA listed —
Aleve 220 mg 66715-9702-01 Lil' 1 tablet — — Discontinued —
Lil Drug Store Pain Relief All Day 220 mg 66715-9740-04 Lil' 12 tablets — — FDA listed —
All Day Pain Relief 220 mg 00363-9608-01 WALGREENS 100 tablets — — FDA listed —
Naproxen 220 mg 71335-1282-01 Bryant 20 tablets — — FDA listed —
Amazon Basic Care Naproxen Sodium 220 mg 72288-0366-20 Amazon.com 200 tablets — — FDA listed —
Naproxen Sodium 220 mg 21130-0061-05 Safeway, 50 tablets — — FDA listed —
Naproxen 220 mg 21130-0674-52 Better 90 tablets — — FDA listed —
Flanax Menstrual Pain Reliever 220 mg 27854-0165-10 Belmora 10 tablets — — FDA listed —
Rapidol Naproxen 220 mg 55758-0048-24 Pharmadel 24 tablets — — FDA listed —
all day relief 220 mg 56062-0490-71 Publix 50 tablets — — FDA listed —
Naproxen Sodium HEADACHE PAIN 220 mg 58602-0735-07 Aurohealth 24 tablets — — FDA listed —
Aleve Back and Muscle Pain 220 mg 00280-0111-01 Bayer 10 tablets — — FDA listed —
Aleve Caplets 220 mg 00280-0114-01 Bayer 200 tablets — — FDA listed —
Aleve, TRAVEL BASIX 220 mg 66715-6411-02 Lil' 2 tablets — — FDA listed —
Naproxen Sodium 220 mg 71141-0182-32 Lidl 100 tablets — — FDA listed —
basic care naproxen sodium 220 mg 72288-0368-75 Amazon.com 90 tablets — — FDA listed —
Naproxen Sodium 220 mg 21130-0856-52 Better 90 tablets — — FDA listed —
naproxen sodium 220 mg 37808-0652-62 H 24 tablets — — FDA listed —
Naproxen Back and Muscle Pain 220 mg 50844-0714-14 L.N.K. 500 tablets — — FDA listed —
Naproxen Sodium 220 mg 51316-0762-70 CVS 270 tablets — — FDA listed —
CAREALL Naproxen 220 mg 51824-0072-01 New 100 tablets — — FDA listed —
exchange select naproxen sodium 220 mg 55301-0368-71 Army 50 tablets — — FDA listed —
Naproxen 220 mg 55319-0717-08 Family 24 tablets — — FDA listed —
Naproxen Sodium HEADACHE PAIN 220 mg 58602-0737-07 Aurohealth 24 tablets — — FDA listed —
Naproxen Sodium 220 mg 58602-0819-07 Aurohealth 24 tablets — — FDA listed —
Artridol 220 mg 59428-0604-08 Zapotol 24 tablets — — FDA listed —
Naproxen Sodium 220 mg 67091-0138-50 WinCo 50 tablets — — FDA listed —
Basic Care Naproxen Sodium 220 mg 72288-0489-75 Amazon.com 90 tablets — — FDA listed —
Naproxen Sodium 220 mg 79903-0232-90 WALMART 90 tablets — — FDA listed —
Aleve Caplets 220 mg 85237-1832-01 Select 1 tablet — — FDA listed —
Naproxen Sodium Headache Pain 220 mg 43598-0071-01 Dr.Reddy's 100 tablets — — FDA listed —
Naproxen Sodium 220 mg 50844-0604-09 L.N.K. 5 tablets — — FDA listed —
Naproxen Sodium 220 mg 53185-0604-12 Athlete's 100 tablets — — FDA listed —
Naproxen Sodium 220 mg 55111-0273-01 Dr.Reddy's 100 tablets — — FDA listed —
Naproxen 220 mg 55319-0406-52 Family 90 tablets — — Discontinued —
DG Health Naproxen Sodium 220 mg 55910-0481-62 Dolgencorp 24 tablets — — FDA listed —
dg health naproxen sodium 220 mg 55910-0729-62 Dolgencorp 24 tablets — — FDA listed —
Aleve Headache Pain 220 mg 00280-0112-01 Bayer 175 tablets — — FDA listed —
Aleve 220 mg 00280-6010-01 Bayer 100 tablets — — FDA listed —
All Day Pain Relief 220 mg 63941-0245-01 VALU 24 tablets — — FDA listed —
kirkland signature naproxen sodium 220 mg 63981-0368-79 Costco 400 tablets — — FDA listed —
Naproxen Sodium 220 mg 68196-0255-20 SAM'S 400 tablets — — FDA listed —
Naproxen Sodium 220 mg 68998-0144-03 Marc 100 tablets — — FDA listed —
Naproxen Sodium 220 mg 83324-0108-01 CHAIN 100 tablets — — FDA listed —
Naproxen Sodium 220 mg 11822-4171-02 Rite 100 tablets — — Discontinued —
signature care naproxen sodium 220 mg 21130-0180-62 Safeway 24 tablets — — Discontinued —
Naproxen Sodium 220 mg 21130-0593-79 Safeway 400 tablets — — FDA listed —
First Aid Direct All Day Pain Relief 220 mg 42961-0122-02 Cintas 1 tablet — — FDA listed —
Naproxen Sodium Headache Pain 220 mg 43598-0072-01 Dr.Reddy's 100 tablets — — FDA listed —
Naproxen Headache Pain 220 mg 50844-0471-14 L.N.K. 500 tablets — — FDA listed —
CAREALL Naproxen Sodium 220 mg 51824-0109-01 New 100 tablets — — FDA listed —
Naproxen Sodium 220 mg 61504-0145-02 AMERIFOODS 50 tablets — — FDA listed —
Aleve 220 mg 66715-6402-08 Lil' 30 tablets — — FDA listed —
Naproxen Sodium 220 mg 67091-0140-10 WinCo 100 tablets — — FDA listed —
Berkley and Jensen Naproxen Sodium 220 mg 68391-0368-79 BJWC 400 tablets — — FDA listed —
All Day Pain Relief 220 mg 79903-0005-10 WALMART 40 tablets — — Discontinued —
up and up naproxen sodium 220 mg 11673-0368-71 Target 50 tablets — — FDA listed —
Naproxen Sodium 220 mg 11673-0764-05 TARGET 50 tablets — — FDA listed —
up and up naproxen sodium 220 mg 11673-0909-75 Target 90 tablets — — FDA listed —
Naproxen Sodium 220 mg 11822-6040-02 Rite 100 tablets — — Discontinued —
good sense naproxen sodium 220 mg 00113-1412-71 L. 50 tablets — — FDA listed —
Topcare All Day Pain Relief 220 mg 36800-0140-82 Topco 200 tablets — — FDA listed —
naproxen sodium 220 mg 37808-0713-79 H 400 tablets — — FDA listed —
equaline naproxen sodium 220 mg 41163-0707-71 United 50 tablets — — FDA listed —
Naproxen Sodium 220 mg 41250-0477-62 Meijer 24 tablets — — FDA listed —
Naproxen Sodium 220 mg 41250-0680-71 Meijer 50 tablets — — FDA listed —
Naproxen Sodium 220 mg 43063-0909-20 PD-Rx 20 tablets — — FDA listed —
Naproxen Sodium Headache Pain Caplets 220 mg 43598-0059-52 Dr.Reddy's 225 tablets — — FDA listed —
Naproxen Sodium Back and Muscle Pain 220 mg 43598-0073-01 Dr.Reddy's 100 tablets — — FDA listed —
Medique Mediproxen 220 mg 47682-0237-33 Unifirst 1 tablet — — FDA listed —
Medique at Home Mediproxen 220 mg 47682-0737-50 Unifirst 1 tablet — — FDA listed —
Naproxen 220 mg 53943-0144-02 DISCOUNT 50 tablets — — FDA listed —
Naproxen Sodium 220 mg 57344-0145-01 AAA 24 tablets — — FDA listed —
Naproxen Sodium 220 mg 58602-0845-21 Aurohealth 100 tablets — — FDA listed —
Aleve 220 mg 00280-0113-01 Bayer 10 tablets — — FDA listed —
Naproxen Sodium 220 mg 63941-0444-01 VALU 24 tablets — — FDA listed —
Naproxen Sodium 220 mg 69848-0010-01 Granules 10 tablets — — FDA listed —
Rugby All Day Relief 220 mg 71335-3009-01 Bryant 20 tablets — — FDA listed —
Naproxen Sodium 220 mg 72789-0543-14 PD-Rx 14 tablets — — FDA listed —
Pain Relief 220 mg 82501-1576-01 Gobrands, 100 tablets — — FDA listed —
Naproxen Sodium 220 mg 83324-0109-01 CHAIN 100 tablets — — FDA listed —
topcare back and muscle pain 220 mg 36800-0696-75 Topco 90 tablets — — FDA listed —
naproxen sodium 220 mg 37808-0631-82 H 200 tablets — — FDA listed —
Naproxen Sodium 220 mg 37835-0594-01 Bi-Mart 100 tablets — — FDA listed —
Care One Naproxen Sodium 220 mg 41520-0533-71 American 50 tablets — — FDA listed —
rugby all day relief 220 mg 50090-3356-00 A-S 30 tablets — — FDA listed —
All Day Relief 220 mg 56062-0368-62 Publix 24 tablets — — FDA listed —
Naproxen Sodium 220 mg 58602-0738-07 Aurohealth 24 tablets — — FDA listed —
Aleve Caplets Soft Grip Arthritis 220 mg 00280-0115-01 Bayer 270 tablets — — FDA listed —
Aleve Gelcaps 220 mg 00280-6020-02 Bayer 90 tablets — — FDA listed —
Aleve Back and Muscle Pain 220 mg 00280-6092-02 Bayer 130 tablets — — FDA listed —
All Day Pain Relief 220 mg 63941-0144-01 VALU 24 tablets — — FDA listed —
Naproxen 220 mg 68788-7572-02 Preferred 20 tablets — — FDA listed —
Good Sense Naproxen Sodium 220 mg 68788-8443-02 Preferred 20 tablets — — FDA listed —
Good Sense Naproxen Sodium 220 mg 71335-2584-01 Bryant 20 tablets — — FDA listed —
equaline naproxen sodium 220 mg 41163-0511-62 United 24 tablets — — FDA listed —
Care One Naproxen Sodium 220 mg 41520-0349-82 American 200 tablets — — FDA listed —
Naproxen Sodium 220 mg 42507-0245-01 HYVEE 24 tablets — — FDA listed —
Bayer Aleve 220 mg 47682-0488-50 Unifirst 50 tablets — — FDA listed —
Naproxen 220 mg 50844-0261-08 L.N.K. 24 tablets — — FDA listed —
Aleve Headache Pain 220 mg 00280-0041-01 Bayer 175 tablets — — FDA listed —
Aleve Gelcaps 220 mg 00280-6070-40 Bayer 40 tablets — — FDA listed —
Naproxen Sodium 220 mg 81522-0045-05 FSA 200 tablets — — FDA listed —
Medique Mediproxen 220 mg 85766-0121-01 Sportpharm 1 tablet — — FDA listed —
Dr Simi All Day Pain Relief 220 mg 85786-0104-24 Farmacias 24 tablets — — FDA listed —
naproxen sodium 220 mg 41250-0313-82 Meijer 200 tablets — — FDA listed —
naproxen sodium 220 mg 41250-0818-62 Meijer 24 tablets — — FDA listed —
Naproxen Sodium 220 mg 42507-0844-01 HYVEE 24 tablets — — FDA listed —
Naproxen Sodium Back and Muscle Pain Caplets 220 mg 43598-0060-52 Dr.Reddy's 225 tablets — — FDA listed —
Calmadol Pain Reliever 220 mg 48201-0007-24 GRANDALL 24 tablets — — FDA listed —
Naproxen Sodium 220 mg 55111-0272-01 Dr.Reddy's 100 tablets — — FDA listed —
Naproxen 220 mg 57896-0954-01 Geri-Care 100 tablets — — FDA listed —
Naproxen Sodium BACK AND MUSCLE PAIN 220 mg 58602-0736-07 Aurohealth 24 tablets — — FDA listed —
Aleve Caplets Easy Open Arthritis 220 mg 00280-0130-01 Bayer 90 tablets — — FDA listed —
Aleve Easy Open Arthritis 220 mg 00280-0131-01 Bayer 200 tablets — — FDA listed —
Aleve Caplets 220 mg 00280-6000-01 Bayer 24 tablets — — FDA listed —
Aleve Headache Pain 220 mg 00280-8252-10 Bayer 10 tablets — — FDA listed —
Naproxen Sodium 220 mg 63868-0466-01 Chain 100 tablets — — FDA listed —
Naproxen Sodium 220 mg 63941-0445-01 VALU 24 tablets — — FDA listed —
All Day Pain Relief 220 mg 00363-0368-61 Walgreen 600 tablets — — Discontinued —
Naproxen Sodium 220 mg 68998-0145-03 Marc 100 tablets — — FDA listed —
All Day Pain Relief 220 mg 00363-6099-01 WALGREENS 100 tablets — — FDA listed —
Aleve 220 mg 70264-0011-01 R 50 tablets — — FDA listed —
Naproxen Sodium 220 mg 71335-1061-01 Bryant 20 tablets — — FDA listed —
Naproxen Sodium 220 mg 72036-0144-01 Harris 24 tablets — — FDA listed —
Naproxen Sodium 220 mg 72036-0145-01 Harris 24 tablets — — FDA listed —
Basic Care Naproxen Sodium 220 mg 72288-0331-62 Amazon.com 24 tablets — — Discontinued —
naproxen sodium 220 mg 72288-0988-75 Amazon.com 90 tablets — — FDA listed —
About this product: this is a generic version of the medicine. FDA equivalence ratings are shown when available, and other versions are listed above, least expensive first.
Where does this data come from?
Equivalents are other NDCs of the same ingredient, form and route from the openFDA NDC Directory, ranked least-expensive-first by NADAC. Therapeutic-equivalence (AB) ratings come from the FDA Orange Book; biologics use the FDA Purple Book for biosimilar & interchangeable status.

Availability & generic status

🏛️
2020
On the market since
Jan 2020
📍
2026
Currently FDA-listed
6 years listed
🔓
·
Generic on the market
this product is a generic
✅This is a generic drug

This product is an FDA-approved generic. Other versions of the same drug are listed under Therapeutic equivalents, least expensive first.

Where does this data come from?
Patents and exclusivity from the FDA Orange Book (small-molecule drugs), refreshed from public FDA data. Generic launch timing is an estimate, not a guarantee.

What it looks like

Color blue
ShapeOval
ImprintNP220
Size2 mm
ScoringNot scored
One label can cover several strengths, so colors may be combined — always confirm a loose pill against the dispensed prescription label or a pharmacist.
Where does this data come from?
Physical description (imprint, shape, color, scoring, coating) from this product’s FDA Structured Product Labeling (SPL), mirrored from DailyMed / openFDA.

Inactive Ingredients / Excipients

Inactive ingredients, also called excipients, are components of the drug product other than the active ingredient. They may include fillers, dyes, coatings, preservatives, flavors, or other formulation ingredients.

🧪 Avoiding an ingredient? See Naproxen inactive ingredients by manufacturer: every current product's list side by side, so you can ask your pharmacy for the version that does not list it.

💡 Tap an ingredient (hover on desktop) to see what it is and why it’s used.

  • UNII H3R47K3TBD
    FD&C Blue No. 1 is a synthetic blue dye approved for use in foods and medicines. It serves as a colorant to give the medication its distinctive appearance and help with product identification.
  • UNII 2G86QN327L
    Gelatin is a protein derived from animal collagen, commonly used in medicines as a gelling agent and capsule material. It helps create soft or hard capsule shells that hold and release medication, and can also thicken liquid formulations.
  • UNII PDC6A3C0OX
    Glycerin is a clear, thick liquid derived from plant oils or fats. It acts as a humectant to retain moisture, a sweetener, and a solvent in medications.
  • UNII 33X04XA5AT
    Lactic acid is a naturally occurring organic acid derived from milk or plant sources. It lowers and maintains pH in formulations, helps preserve the product, and can enhance ingredient stability and absorption.
  • UNII 3WJQ0SDW1A
    Polyethylene glycol is a synthetic liquid or solid polymer used in medicines as a solvent, lubricant, and humectant. It helps dissolve active ingredients, reduces friction during manufacturing, and retains moisture in the final product.
  • UNII 6O92ICV9RU
    A waxy substance derived from sorbitol that helps mix oil and water together in medicines. It's used as an emulsifier to keep ingredients evenly blended and stable.
  • UNII 506T60A25R
    Sorbitol is a natural sugar alcohol derived from glucose. It serves as a sweetener, humectant, and bulking agent in medications to improve taste and help maintain moisture in the product.

7 inactive ingredients listed in the exact product block matched to this NDC.

The official label also statesFD&C blue #1, gelatin, glycerin, lactic acid, polyethylene glycol, sorbitan, sorbitol, white pharmaceutical ink

Label-section wording can be broader than the structured product block and may mention additional formulation ingredients.

Where does this data come from?
Data sourced from official FDA Structured Product Labeling (SPL) via DailyMed — ingredient classCode="IACT" elements from the exact product block matched by this NDC. Label-section narrative from DailyMed / the openFDA label index is shown separately when available.

Inactive ingredient FAQ

Are inactive ingredients the same for every manufacturer?
No. Inactive ingredients can differ by manufacturer, dosage form, strength, and package / product version.
Why might an inactive ingredient be missing?
Some SPLs do not provide a complete structured inactive-ingredient list, and older or unusual labels may only include the information in narrative text.
Can inactive ingredients matter?
Yes. They can matter for allergies, intolerances, dyes, gluten / lactose concerns, preservatives, and formulation differences — but confirm with a pharmacist or the manufacturer when it’s clinically important.

Manufacturer & labeler

LabelerWalgreens
Application holderCATALENT PHARMA SOLUTIONS LLC
FDA applicationANDA202807 (ANDA)
Labeler code00363
First marketedJan 2020
Product typeHuman Otc Drug
Portfolio342 products on file

More NDCs from Walgreens labeler code 00363

The labeler markets the product; the application holder owns the FDA approval. They’re often the same company but can differ (e.g. a repackager or an authorized generic). A mailing address / phone appears here when the manufacturer includes it in the product’s FDA label (not all do).
Where does this data come from?
Labeler, application holder and registered establishment from the FDA openFDA NDC Directory and Drugs@FDA; address/contact from the product’s FDA label.

FDA label — Drug Facts FDA SPL

The complete FDA label for this product — the official Drug Facts labeling, verbatim, section by section. Jump with a chip, search within the label, or expand everything.
🎯 Indications and Usage ⏱️ Dosage and Administration ⚠️ Warnings 📦 Storage and Handling 🧪 Active Ingredient 🧪 Inactive Ingredients 🎯 Purpose 📄 Do Not Use 📄 Ask a Doctor Before Use If 📄 Ask a Doctor or Pharmacist Before Use If 📄 When Using This Product 📄 Stop Use and Ask a Doctor If 🤰 If Pregnant or Breast-Feeding 📄 Keep Out of Reach of Children 📄 Questions or Comments 📄 Package Label / Principal Display Panel
🎯 Indications and Usage 26 words ▾

Uses temporarily relieves minor aches and pains due to: minor pain of arthritis muscular ache backache menstrual cramp headache toothache the common cold temporarily reduces fever

⏱️ Dosage and Administration 92 words ▾

Directions do not take more than directed the smallest effective dose should be used drink a full glass of water with each dose if taken with food, this product may take longer to work adults and children 12 years and older: take 1 tablet every 8 to 12 hours while symptoms last for the first dose you may take 2 tablets within the first hour do not exceed 2 tablets in any 8- to 12-hour period do not exceed 3 tablets in a 24-hour period children under 12 years: ask a doctor

⚠️ Warnings ~2 min read ▾

Warnings Allergy alert: Naproxen sodium may cause a severe allergic reaction, especially in people allergic to aspirin. Symptoms may include: hives facial swelling asthma (wheezing) shock skin reddening rash blisters If an allergic reaction occurs, stop use and seek medical help right away. Stomach bleeding warning: This product contains an NSAID, which may cause severe stomach bleeding.

The chance is higher if you: are age 60 or older have had stomach ulcers or bleeding problems take a blood thinning (anticoagulant) or steroid drug have 3 or more alcoholic drinks every day while using this product take other drugs containing prescription or nonprescription NSAIDs (aspirin, ibuprofen, naproxen, or others) take more or for a longer time than directed Heart attack and stroke warning : NSAIDs, except aspirin, increase the risk of heart attack, heart failure, and stroke. These can be fatal. The risk is higher if you use more than directed or for longer than directed Do not use if you have ever had an allergic reaction to any other pain reliever/fever reducer right before or after heart surgery Ask a doctor before use if the stomach bleeding warning applies to you you have a history of stomach problems, such as heartburn you have high blood pressure, heart disease, liver cirrhosis, kidney disease, asthma, or had a stroke you have problems or serious side effects from taking pain relievers or fever reducers you are taking a diuretic Ask a doctor or pharmacist before use if you are under a doctor’s care for any serious condition taking aspirin for heart attack or stroke, because naproxen may decrease this benefit of aspirin taking any other drug When using this product take with food or milk if stomach upset occurs.

Stop use and ask a doctor if you experience any of the following signs of stomach bleeding: feel faint have bloody or black stools vomit blood have stomach pain that does not get better you have symptoms of heart problem or stroke: chest pain trouble breathing weakness in one part or side of body slurred speech leg swelling pain gets worse or lasts more than 10 days fever gets worse or lasts more than 3 days redness or swelling is present in the painful area any new symptoms appear you have difficulty swallowing it feels like the capsule is stuck in your throat If pregnant or breast-feeding, ask a health professional before use.

It is especially important not to use naproxen sodium during the last 3 months of pregnancy unless definitely directed to do so by a doctor because it may cause problems in the unborn child or complications during delivery. Keep out of reach of children. In case of overdose, get medical help or contact a Poison Control Center (1-800-222-1222) right away.

📦 Storage and Handling 58 words ▾

Other information each tablet contains: sodium 20 mg store at 20º to 25°C (68º to 77°F). excursions permitted between 15ºC and 30ºC (59ºF to 86ºF)[See USP Controlled Room Temperature]. Avoid high humidity and excessive heat above 40°C (104°F). Protect from Light. read all directions and warnings before use. Keep carton. swallow whole: do not crush, chew or dissolve

🧪 Active Ingredient 16 words ▾

Active ingredient (in each capsule) Naproxen sodium 220 mg (naproxen 200 mg) (NSAID)* *nonsteroidal anti-inflammatory drug

🧪 Inactive Ingredients 16 words ▾

Inactive ingredients FD&C blue #1, gelatin, glycerin, lactic acid, polyethylene glycol, sorbitan, sorbitol, white pharmaceutical ink

🎯 Purpose 4 words ▾

Purposes Pain reliever/fever reducer

📄 Do Not Use 23 words ▾

Do not use if you have ever had an allergic reaction to any other pain reliever/fever reducer right before or after heart surgery

📄 Ask a Doctor Before Use If 58 words ▾

Ask a doctor before use if the stomach bleeding warning applies to you you have a history of stomach problems, such as heartburn you have high blood pressure, heart disease, liver cirrhosis, kidney disease, asthma, or had a stroke you have problems or serious side effects from taking pain relievers or fever reducers you are taking a diuretic

📄 Ask a Doctor or Pharmacist Before Use If 37 words ▾

Ask a doctor or pharmacist before use if you are under a doctor’s care for any serious condition taking aspirin for heart attack or stroke, because naproxen may decrease this benefit of aspirin taking any other drug

📄 When Using This Product 13 words ▾

When using this product take with food or milk if stomach upset occurs.

📄 Stop Use and Ask a Doctor If 103 words ▾

Stop use and ask a doctor if you experience any of the following signs of stomach bleeding: feel faint have bloody or black stools vomit blood have stomach pain that does not get better you have symptoms of heart problem or stroke: chest pain trouble breathing weakness in one part or side of body slurred speech leg swelling pain gets worse or lasts more than 10 days fever gets worse or lasts more than 3 days redness or swelling is present in the painful area any new symptoms appear you have difficulty swallowing it feels like the capsule is stuck in your throat

🤰 If Pregnant or Breast-Feeding 48 words ▾

If pregnant or breast-feeding, ask a health professional before use. It is especially important not to use naproxen sodium during the last 3 months of pregnancy unless definitely directed to do so by a doctor because it may cause problems in the unborn child or complications during delivery.

📄 Keep Out of Reach of Children 22 words ▾

Keep out of reach of children. In case of overdose, get medical help or contact a Poison Control Center (1-800-222-1222) right away.

📄 Questions or Comments 8 words ▾

Questions or comments? Call 1-877-753-3935 Monday-Friday 9AM-5PM EST

📄 Package Label / Principal Display Panel 102 words ▾

Principal Display Panel Compare to the active ingredient in Aleve® Liquid Gels†† All Day Pain Relief NAPROXEN SODIUM CAPSULES, 220 mg (NSAID) / PAIN RELIEVER / FEVER REDUCER 12 HOUR LIQUID GELS** (**Liquid-filled capsules) ††This product is not manufactured or distributed by Bayer Healthcare, LLC, distributor of Aleve® Liquid Gels. TAMPER EVIDENT: DO NOT USE IF PRINTED SAFETY SEAL UNDER CAP IS BROKEN OR MISSING KEEP OUTER CARTON FOR COMPLETE WARNINGS AND PRODUCT INFORMATION DISTRIBUTED BY: WALGREEN CO. 200 WILMOT RD., DEERFIELD, IL 60015

Package Label WALGREENS All Day Pain Relief Naproxen Sodium 220 mg (naproxen 200 mg) (NSAID)* *nonsteroidal anti-inflammatory drug

Source: FDA Structured Product Labeling, mirrored from DailyMed / openFDA. Prefer the government’s original formatting? View this label on DailyMed ↗

Medicare Part D spend CMS · PART D · 2026 (Q1)

Medicare Part D (outpatient prescription) spending for Naproxen Sodium — the program that covers self-administered drugs. 4 manufacturers.
⚠️ Drug-level data: CMS publishes Part D spending by drug, not by NDC — these figures combine every manufacturer, strength and package size sold under the name Naproxen Sodium. That’s a different level of aggregation than the Medicaid card above, which is specific to this exact 11-digit NDC (pack size included), so the two aren’t directly comparable.
Period
Total Part D spend
$441.8K
Claims incl. refills
15.2K
Beneficiaries
11.4K
Spend / beneficiary
$38.70
Spend / claim
$29.13
Trend by period
💵 About the dollar figures: spending is what Part D plans paid before confidential manufacturer rebates, so the program’s real net cost is lower. A blank patient count means fewer than 11 people — CMS hides counts that small to protect privacy. Source: CMS Medicare Quarterly Part D Spending by Drug (data.cms.gov), updated quarterly.

About this NDC listing & data coverage

Over-the-counter (OTC) product
What data is (and isn’t) available for this NDC — tap to expand
NDC identity (package / product / labeler codes) ✓ Available
Labeler ✓ Available
Product & package description ✓ Available
Marketing category & status ✓ Available
Active ingredient / dosage form / route ✓ Available
FDA label (SPL via DailyMed) ✓ Available
Package photos ✓ Available
Inactive ingredients (structured) ✓ Available
NADAC pharmacy acquisition price (CMS) — Not published for this NDC CMS publishes NADAC only for NDCs reported in its retail-pharmacy survey.
Orange Book / therapeutic-equivalence data — Not published for this NDC Applies only to products approved under an NDA/ANDA; many listings are out of scope.
HCPCS J-code billing crosswalk — Not published for this NDC Most self-administered / retail products have no J-code — that is normal.
Medicaid utilization (CMS SDUD) — Not published for this NDC CMS reports utilization only for NDCs with Medicaid claims above its privacy threshold.
“Not published” reflects what the public FDA / CMS / NLM sources provide for this exact package code — it is a property of the data feeds, not a judgment about the product.

Questions about this listing

Why is there no price listed?
The pricing shown on our NDC pages comes from CMS NADAC, a voluntary survey of retail community pharmacy invoices. CMS does not publish a NADAC for every NDC — packages outside the retail survey (institutional and hospital products, bulk packages, discontinued items, and many OTC items) may never receive one. A missing price reflects the survey's scope, not this product's actual cost, and does not mean the product is free or unavailable.
Is the NDC printed on the package the same as the 11-digit billing NDC?
Yes, they identify this exact package in different formats. The form printed on the packaging and shown on DailyMed is the one the FDA registered. Insurance claims use a fixed 11-digit 5-4-2 format, so the short segment is padded with a leading zero and the dashes are dropped. The Identity section at the top of this page lists each form of this code.
Is this package still being marketed?
Yes, per the latest FDA NDC Directory data on this page: this package is listed as actively marketed, with no marketing end date reported by Walgreens. Listing status can change — the directory data on this page refreshes weekly.
Does this product come in other package sizes?
Yes — the FDA directory lists 3 other package presentations of this same product, including 20 tablets (00363-7510-20), 40 tablets (00363-7510-40), 50 tablets (00363-7510-50). Each has its own NDC and its own page — see the package list near the top of this page.
Who lists this product with the FDA?
Walgreens is the labeler of record for this NDC — the company under whose FDA-assigned code the package is listed. The labeler may be the manufacturer itself or a distributor marketing the product under its own code.
Do I need a prescription for this product?
This NDC is listed with FDA as an over-the-counter product, so it does not require a prescription. Follow the package directions, and ask your pharmacist if you are unsure whether it is right for you.
This page identifies an FDA-listed package (the NDC) and reports public regulatory and pricing data about the listing. It is reference information, not a medical recommendation — talk to your pharmacist or prescriber about your own medication.
Where does this data come from?
Listing facts (marketing category, packager status, marketing dates) from the FDA openFDA NDC Directory; label availability from DailyMed; pricing coverage from CMS NADAC; equivalence scope from the FDA Orange Book.
← 00363-7504-04 · WALGREENS 00363-7550-04 · WALGREENS →
For educational and professional reference only — not medical advice. Pricing reflects published NADAC and CMS ASP (free public data) and may differ from your acquisition cost; always verify before billing or dispensing.