Stool Softener Laxative Docusate Sodium 250 mg Capsule, Liquid Filled, 100-count
by Major Pharmaceuticals · 100 CAPSULE, LIQUID FILLED in 1 BOTTLE, PLASTIC (0904-7281-60)
NDC 00904-7281-60
🏷️ FDA NDC (as labeled)
0904-7281-60
billing pads the labeler segment with a zero
This package
Also priced by: Medicaid pays $0.1970/unit — full pricing hub ↓
Also comes in:
1000 capsules 00904-7281-80
OTC
On market
Non-controlled
🗂️ Data synced Jul 24, 2026 · sources: openFDA · FDA label (DailyMed) · FDA Orange & Purple Book · First Databank · CMS NADAC, ASP, Medicare & Medicaid · RxNorm
📋 All sources & update times →
🆔 Identity & classification
FDA NDC (as labeled)
0904-7281-60
Product NDC
0904-7281
11-digit billing NDC
00904728160
NCPDP billing unit
EA — each (per item)
RxCUI
1245468
UNII
F05Q2T2JA0
UPC
0309047281602
Application #
M007
SPL Set ID
93ef6486-0930-41e3-a2c6-44af7e37e98b
DEA schedule
Non-controlled
Marketing category
OTC MONOGRAPH DRUG
Marketing status
On market
FDA listing status
Listed (active directory)
Marketing start
2022-10-14
Route
ORAL
Dosage form
CAPSULE, LIQUID FILLED
Substance
DOCUSATE SODIUM
GPI-14
46500010300120
GCN Seq No
003011
GCN
09102
HICL code
001326
Ingredient (HICL)
Docusate Sodium
HIC1 code
D
Therapeutic class — broad (HIC1)
Biliary System/Gastro-Intestinal System
HIC2 code
D6
Therapeutic class — intermediate (HIC2)
Drugs Acting Principally On The Colon
HIC3 code
D6S
Therapeutic class — specific (HIC3)
Laxatives And Cathartics
AHFS code
56:12.00.00
AHFS class
Cathartics And Laxatives
FDB label name
DOCUSATE SODIUM 250 MG SOFTGEL
FDB brand name
Docusate Sodium
Legend status
O — Over-the-counter (OTC) drug or device
Why two NDCs?
The FDA registers this code as 0904-7281-60 — a 4-4-2 layout, and that's what's printed on the package and shown on DailyMed. For insurance claims, every NDC is standardized to a uniform 11-digit 5-4-2 format by adding a zero to the labeler segment → 00904-7281-60. Same drug, same package — only the format differs.
Where does this data come from?
Identifiers from the FDA openFDA NDC Directory and Structured Product Labeling; RxCUI from RxNorm (NLM); GPI from Medi-Span; GCN / HIC / AHFS / legend from First Databank.
🏷️ RxNorm drug class
This medicine belongs to the Softeners, emollients class.
Drug family (ATC)
Softeners, emollients
Where does this data come from?
Therapeutic classes from RxNorm RxClass (U.S. National Library of Medicine) — Established Pharmacologic Class (FDA), ATC drug family (WHO) and mechanism of action, matched by this product’s RxCUI.
🏭 Manufacturer & labeler
LabelerMajor Pharmaceuticals
FDA applicationM007 (OTC MONOGRAPH DRUG)
Labeler code00904
First marketedOct 2022
Product typeHuman Otc Drug
Portfolio629 products on file
The labeler markets the product; the application holder owns the FDA approval. They’re often the same company but can differ (e.g. a repackager or an authorized generic). A mailing address / phone appears here when the manufacturer includes it in the product’s FDA label (not all do).
Where does this data come from?
Labeler, application holder and registered establishment from the FDA openFDA NDC Directory and Drugs@FDA; address/contact from the product’s FDA label.
🩺 Clinical
Label name DOCUSATE SODIUM 250 MG SOFTGEL Ingredient Docusate Sodium
📖 About the active ingredient: Docusate Sodium MedlinePlus · NLM
General information about the ingredient itself — the description of this specific product follows below.
Stool softeners are used on a short-term basis to relieve constipation by people who should avoid straining during bowel movements because of heart conditions, hemorrhoids, and other problems. They work by softening stools to make them easier to pass.
Read the full MedlinePlus article ↗🧪 What is this product?
This is an oral capsule containing docusate sodium, an over-the-counter stool softener marketed under FDA's monograph rules for laxatives. Docusate sodium is typically used to soften stool and make bowel movements easier, often taken by people who want to avoid straining. It works by helping water mix into the stool rather than by stimulating bowel movement itself, making it a gentler option in the laxative category.
Patient education
Supplement & herbal interactions
Some supplements/herbs that may interact with Docusate Sodium — tap one for details:
Where does this data come from?
Plain-language summary from MedlinePlus (U.S. National Library of Medicine); supplement & herbal interactions and nutrient depletion data from the Natural Medicines database; our full guide is HelloPharmacist editorial content.
💬 Questions about Docusate Sodium?
Ask a pharmacist →
Ask a licensed pharmacist directly — free, answered by our team.
💊 What it looks like
Color
orange
ShapeCapsule
ImprintP4
Size2 mm
ScoringNot scored
One label can cover several strengths, so colors may be combined — always confirm a loose pill against the dispensed prescription label or a pharmacist.
Where does this data come from?
Physical description (imprint, shape, color, scoring, coating) from this product’s FDA Structured Product Labeling (SPL), mirrored from DailyMed / openFDA.
🧪 Inactive Ingredients / Excipients
Inactive ingredients, also called excipients, are components of the drug product other than the active ingredient. They may include fillers, dyes, coatings, preservatives, flavors, or other formulation ingredients.
💡 Tap an ingredient (hover on desktop) to see what it is and why it’s used.
-
UNII XF417D3PSL
Anhydrous citric acid is a sour, crystalline powder derived from citric acid with water removed. In medicines, it acts as a buffer to control pH, adds tartness to improve taste, and helps tablets disintegrate.
-
UNII WZB9127XOA
A synthetic red dye used to color medications and make them easier to identify. It serves as a colorant in tablets, capsules, and liquid formulations.
-
UNII H77VEI93A8
A synthetic yellow dye used to color medications. It helps identify the drug and make it visually distinctive, with no effect on how the medicine works.
-
UNII 2G86QN327L
Gelatin is a protein derived from animal collagen, commonly used in medicines as a gelling agent and capsule material. It helps create soft or hard capsule shells that hold and release medication, and can also thicken liquid formulations.
-
UNII PDC6A3C0OX
Glycerin is a clear, thick liquid derived from plant oils or fats. It acts as a humectant to retain moisture, a sweetener, and a solvent in medications.
-
UNII ND2M416302
Isopropyl alcohol is a clear liquid solvent derived from petroleum. In medicines, it dissolves active ingredients and other components, helps the product flow smoothly, and aids in sterilization during manufacturing.
-
UNII 1DI56QDM62
A natural fatty substance from soybeans that helps mix oil and water-based ingredients together. It acts as an emulsifier and lubricant in medicines to improve texture and help the product break down properly in your body.
-
UNII 3OWL53L36A
A natural sugar alcohol derived from seaweed or synthesized in the lab. It's used as a filler to add bulk, a sweetener in sugar-free formulas, and a disintegrant to help tablets break apart in the stomach.
-
UNII T5L8T28FGP
Mineral oil is a clear, odorless liquid derived from crude oil. It acts as a lubricant and emollient in medications, helping pills slide smoothly during manufacturing and aiding moisture retention in topical products.
-
UNII 3WJQ0SDW1A
Polyethylene glycol is a synthetic liquid or solid polymer used in medicines as a solvent, lubricant, and humectant. It helps dissolve active ingredients, reduces friction during manufacturing, and retains moisture in the final product.
-
UNII 6DC9Q167V3
Propylene glycol is a clear liquid derived from petroleum or vegetable sources. It acts as a solvent, humectant, and preservative in medicines, helping dissolve active ingredients and maintain product stability.
-
UNII 6O92ICV9RU
A waxy substance derived from sorbitol that helps mix oil and water together in medicines. It's used as an emulsifier to keep ingredients evenly blended and stable.
-
UNII 506T60A25R
Sorbitol is a natural sugar alcohol derived from glucose. It serves as a sweetener, humectant, and bulking agent in medications to improve taste and help maintain moisture in the product.
-
UNII 059QF0KO0R
Water is a liquid solvent that dissolves and mixes ingredients together in liquid medicines, syrups, and injections. It helps distribute the active drug evenly throughout the product.
14 inactive ingredients listed in the exact product block matched to this NDC.
The official label also statesanhydrous citric acid, FD&C red #40, FD&C yellow #6, gelatin, glycerin, isopropyl alcohol, lecithin, mannitol, mineral oil, polyethylene glycol, propylene glycol, purified water, sorbitan, sorbitol, white ink
Label-section wording can be broader than the structured product block and may mention additional formulation ingredients.
Where does this data come from?
Data sourced from official FDA Structured Product Labeling (SPL) via DailyMed —
ingredient classCode="IACT" elements from the exact product block matched by this NDC. Label-section narrative from DailyMed / the openFDA label index is shown separately when available.Inactive ingredient FAQ
Are inactive ingredients the same for every manufacturer?
No. Inactive ingredients can differ by manufacturer, dosage form, strength, and package / product version.
Why might an inactive ingredient be missing?
Some SPLs do not provide a complete structured inactive-ingredient list, and older or unusual labels may only include the information in narrative text.
Can inactive ingredients matter?
Yes. They can matter for allergies, intolerances, dyes, gluten / lactose concerns, preservatives, and formulation differences — but confirm with a pharmacist or the manufacturer when it’s clinically important.
💲 Pricing
A drug doesn't have one price. Each row is a different public payment system, and none is what you'd pay at the counter — that depends on your insurance. The ⓘ on each row explains what it measures.
| Price system | Per ea | Per package |
|---|---|---|
| Retail pharmacies payNADAC · weekly | $0.054 | $5.41 / 100 capsules |
| Medicaid paysCMS SDUD · 12 mo | $0.1970 | $19.70 / 100 capsules |
| Medicare drug plans payPart D · quarterly | No Part D plan price is available for this NDC in our data. | |
NADAC price history (per ea) — tap or hover for the price & month
▲ Up 12% over the last 12 months.
Where does this data come from?
NADAC (National Average Drug Acquisition Cost) is the CMS weekly pharmacy-acquisition-cost survey — what pharmacies pay. ASP (Average Sales Price) is the CMS Medicare Part B drug-payment file, published quarterly. Medicaid pays is computed by us from CMS State Drug Utilization Data (total reimbursed ÷ units, trailing 12 months) — gross of rebates and inclusive of dispensing fees, so it reflects what Medicaid paid, not an acquisition cost. Medicare drug plans pay is the median negotiated point-of-sale unit cost across plans listing this NDC in the CMS quarterly Prescription Drug Plan pricing files, before rebates. The VA pays is the federal contract price (FSS, and the statutory Big 4 ceiling where listed) from the VA National Acquisition Center pharmaceutical price file. All are free public government data; each measures a different payer, so the figures are not directly comparable.
🔁 Therapeutic equivalents
| Product | Labeler | Pack | NADAC/unit | TE | Status | Price vs. this |
|---|---|---|---|---|---|---|
| Stool Softener Laxative 250 mgthis 00904-7281-60 | Major | 100 capsules | $0.054 | — | Availability likely | — |
| Good Neighbor Stool Softener laxative 250 mg 46122-0693-78 | AmerisourceBergen | 100 capsules | $0.054 | — | Availability likely | — |
| Stool Softener 250 mg 46122-0826-74 | Amerisource | 100 capsules | $0.054 | — | Availability likely | — |
| Docusate Sodium 250 mg 50268-0268-15 | AvPAK | 1 capsule | $0.054 | — | Availability likely | — |
| Stool Softener 250 mg 70677-1096-01 | Strategic | 100 capsules | $0.054 | — | Availability likely | — |
| Preferred Stool Softener laxative 250 mg 10956-0781-00 | Reese | 140 capsules | — | — | FDA listed | — |
| Stool Softener Laxative 250 mg 17856-7281-01 | ATLANTIC | 1 capsule | — | — | FDA listed | — |
| Stool Softener Laxative Extra Strength 250 mg 36800-0568-10 | TOP | 100 capsules | — | — | Discontinued | — |
| Stool Softener 250 mg 36800-0640-10 | TOP | 100 capsules | — | — | FDA listed | — |
| H E B Stool Softener laxative 250 mg 37808-0293-88 | H | 140 capsules | — | — | FDA listed | — |
| Stool Softener 250 mg 37808-0585-14 | HEB | 140 capsules | — | — | FDA listed | — |
| Stool Softener 250 mg 37808-0879-14 | H | 140 capsules | — | — | FDA listed | — |
| Stool Softener 250 mg 37835-0223-01 | Bi-Mart | 100 capsules | — | — | FDA listed | — |
| Stool Softener Extra Strength 250 mg 41250-0859-10 | MEIJER, | 100 capsules | — | — | FDA listed | — |
| Stool Softener Extra Strength 250 mg 49035-0378-14 | EQUATE | 140 capsules | — | — | FDA listed | — |
| Prolaxa 250 mg 53225-2001-01 | Terrain | 100 capsules | — | — | FDA listed | — |
| Docusate Sodium 250 mg 53345-0035-01 | Humanwell | 7000 capsules | — | — | FDA listed | — |
| Docusate Sodium 250 mg 54629-0601-01 | National | 100 capsules | — | — | FDA listed | — |
| Docusate Sodium 250 mg 55154-4341-00 | Cardinal | 1 capsule | — | — | Discontinued | — |
| Stool Softener Extra Strength 250 mg 55910-0879-10 | Dolgencorp, | 100 capsules | — | — | FDA listed | — |
| Stool Softener 250 mg 57896-0426-01 | Geri-Care | 100 capsules | — | — | FDA listed | — |
| Stool Softener Extra Strength 250 mg 59726-0058-25 | P | 250 capsules | — | — | FDA listed | — |
| Stool Softener Laxative Extra Strength 250 mg 59726-0059-10 | P | 100 capsules | — | — | FDA listed | — |
| Stool Softener Laxative Extra Strength 250 mg 59726-0879-10 | P | 100 capsules | — | — | FDA listed | — |
| Quality Choice Stool Softener laxative 250 mg 63868-0662-01 | Chain | 100 capsules | — | — | FDA listed | — |
| Colace Extra Strength Stool Softner 250 mg 67618-0201-12 | Atlantis | 60 capsules | — | — | FDA listed | — |
| Stool Softener Laxative 250 mg 68016-0471-01 | Chain | 100 capsules | — | — | FDA listed | — |
| Stool Softener Extra Strength 250 mg 68016-0587-00 | Chain | 100 capsules | — | — | FDA listed | — |
| Stool Softener 250 mg 68071-5297-06 | NuCare | 60 capsules | — | — | FDA listed | — |
| Stool Softener Extra Strength 250 mg 69842-0740-25 | CVS | 250 capsules | — | — | FDA listed | — |
| Stool Softener Extra Strength 250 mg 69842-0879-25 | CVS | 250 capsules | — | — | FDA listed | — |
| Stool Softener 250 mg 71335-1677-01 | Bryant | 30 capsules | — | — | FDA listed | — |
| Docusate Sodium 250 mg 72789-0166-60 | PD-Rx | 60 capsules | — | — | FDA listed | — |
| Topcare Stool Softener laxative 250 mg 76162-0764-10 | TOPCO | 100 capsules | — | — | FDA listed | — |
| Stool Softener Laxative Extra Strength 250 mg 79903-0073-14 | WALMART | 140 capsules | — | — | FDA listed | — |
| Prolaxa 250 mg 80425-0540-01 | Advanced | 100 capsules | — | — | FDA listed | — |
| Docusate Sodium, Extra Strength 250 Mg 80513-0100-01 | Advanced | 100 capsules | — | — | FDA listed | — |
| Docusate Sodium, Extra Strength 250 Mg 80513-0101-01 | Advanced | 100 capsules | — | — | FDA listed | — |
| Stool Softener Laxative 250 mg 71335-2313-01 | Bryant | 30 capsules | — | — | FDA listed | — |
About this product: other versions of the same ingredient, strength and form are listed above, least expensive first, with FDA equivalence ratings where available.
Where does this data come from?
Equivalents are other NDCs of the same ingredient, form and route from the openFDA NDC Directory, ranked least-expensive-first by NADAC. Therapeutic-equivalence (AB) ratings come from the FDA Orange Book; biologics use the FDA Purple Book for biosimilar & interchangeable status.
⏳ Availability & generic status
🏛️
2022
On the market since
Oct 2022
📍
2026
Currently FDA-listed
4 years listed
🔒
·
No generic listed yet
brand only
ℹ️No FDA-approved generic found
We did not find an FDA-approved generic match for this exact strength, form and route.
Where does this data come from?
Patents and exclusivity from the FDA Orange Book (small-molecule drugs), refreshed from public FDA data. Generic launch timing is an estimate, not a guarantee.
🗺️ Medicaid utilization & spend
📍 This exact package only: Medicaid data is reported per full 11-digit NDC — labeler, product and pack size — so every number here is for 00904-7281-60, not the drug overall. Other pack sizes report separately.
💊 Pharmacy benefit only: These are Medicaid outpatient pharmacy claims, billed by NDC. They exclude the medical benefit — clinic- or hospital-administered drugs billed under HCPCS J-codes — so drugs used mostly that way (e.g. Avastin, Lucentis, Keytruda) can look low or missing here. That’s expected, not an error.
📅 Q1 2025 – Q1 2026 · 5 quarters of data
ⓘ The newest quarter is usually incomplete when first published; states restate recent quarters in later CMS releases, so the latest figures typically revise upward. State coverage-policy changes can also shift quarter-to-quarter totals.
Prescriptions last 4 qtrs
57.8K
Units reimbursed last 4 qtrs
2.9M
Gross reimbursed last 4 qtrs
$579.9K
Avg / prescription
$10.03
Avg / unit
$0.1970
Latest quarter Q1 2026
6.9KRx
Medicaid pays / ea
$0.1970
gross reimbursed
vs
NADAC / ea
$0.0541
acquisition cost
=
Spread
+$0.1429
+264% vs cost
What Medicaid paid per ea (before rebates; includes the pharmacy’s dispensing fee) compared with NADAC — the average price pharmacies pay to buy the drug. A positive spread means Medicaid reimbursed more than the purchase price, before manufacturer rebates.
Fee-for-service vs managed care ⓘ
Fee-for-service · 40,434 Rx Managed care · 17,368 Rx
State Medicaid map
Units reimbursed · per 100k residents
17.44,914
gray = no data reported ⓘ
Colors are per 100,000 residents, so big states don’t automatically dominate. Tap or hover a state for its actual totals.
Tap or hover a state
…for its Medicaid breakdown
Prescriptions—
Units—
Reimbursed—
🏆 Top states by units · per 100k residents
National units — by quarter
💵 About the dollar figures: “reimbursed” is what Medicaid paid pharmacies before confidential manufacturer rebates, so the program’s real net cost is lower than these numbers. Fee-for-service and managed-care claims are combined unless split above. Source: CMS State Drug Utilization Data; per-100k rates use 2023 Census population estimates.
💊 Medicaid utilization by pack size
Medicaid (SDUD) totals over the four most recent reported quarters for every package size of this drug — handy when a specific package (e.g. a starter/titration pack) carries little or no Medicaid volume on its own.
Drug total (last 4 qtrs): 154,190 Rx · 7,700,528 units · $1,790,092 gross reimbursed
Tap a pack size to open its page. Source: CMS State Drug Utilization Data, last 4 quarters.
🔬 Reported adverse events (FAERS)
Read carefully: FAERS reports are voluntary and unverified. Counts are not incidence, do not establish causation, are subject to reporting bias, and cannot be used to compare one drug to another. Shown for signal context only. Reports for Stool Softener Laxative (this brand).
Top reported reactions
Age at onset
Reporter sex
Male · 43%
Female · 57%
Unknown · 0%
Serious outcomes
Reports over time (by year) — tap or hover for the count & year
Most recent year is provisional (FAERS lags ~3 months).
Where does this data come from?
Adverse-event reports from the FDA Adverse Event Reporting System (FAERS) via openFDA. FAERS reports are voluntary and unverified — counts are not incidence and don’t establish causation.
📦 Packaging — all sizes for this product
| Package NDC | Description | Per unit | Per pack | Marketing start | Status |
|---|---|---|---|---|---|
| 00904-7281-60 You're viewing this | 100 CAPSULE, LIQUID FILLED in 1 BOTTLE, PLASTIC (0904-7281-60) | $0.0541 / ea | $5.41 | 2022-10-14 | Active |
| 00904-7281-80 | 1000 CAPSULE, LIQUID FILLED in 1 BOTTLE, PLASTIC (0904-7281-80) | $0.0541 / ea | $54.09 | 2022-10-14 | Active |
You're viewing the smallest of 2 pack sizes for this product.
This pack has the lowest per-ea cost of the 2 priced pack sizes ($0.0541 NADAC).
This pack accounts for about 37% of this product's recent Medicaid fills; most go to the 1000 capsules pack. See all packs ↓
Pack size FAQ
What quantity is in NDC 00904-7281-60?
NDC 00904-7281-60 is a 100-count package — 100 capsule, liquid filled in 1 bottle, plastic.
What is the difference between NDC 00904-7281-60 and NDC 00904-7281-80?
Both are Stool Softener Laxative Docusate Sodium 250 mg Capsule, Liquid Filled — the drug itself is identical. NDC 00904-7281-60 is the 100-count package, while NDC 00904-7281-80 is the 1000 capsules package.
What NDC number is used to bill for this package of Stool Softener Laxative Docusate Sodium 250 mg Capsule, Liquid Filled?
Bill NDC 00904-7281-60 — the 11-digit billing format is 00904728160. Pharmacy and medical claims use the 11-digit form; the FDA label may print a shorter form of the same code.
Prices are the latest CMS NADAC pharmacy acquisition cost per NDC; per-pack figures are per-unit × pack quantity, shown only when the pack is denominated in the same measure NADAC prices.
📄 FDA label — Drug Facts FDA SPL
The complete FDA label for this product — the official Drug Facts labeling, verbatim, section by section. Jump with a chip, search within the label, or expand everything.
🎯 Indications and Usage
⏱️ Dosage and Administration
⚠️ Warnings
📦 Storage and Handling
🧪 Active Ingredient
🧪 Inactive Ingredients
🎯 Purpose
🎯 Indications and Usage ▾
Uses relieves occasional constipation (irregularity) this product generally produces a bowel movement within 12 to 72 hours
⏱️ Dosage and Administration ▾
Directions adults and children 12 years of age and over: take 1 softgel daily or as directed by a doctor children under 12 years of age: ask a doctor
⚠️ Warnings ▾
Warnings Do not use if you are presently taking mineral oil, unless directed by a doctor. Ask a doctor before use if you have stomach pain nausea vomiting noticed a sudden change in bowel habits that last over 2 weeks Stop use and ask a doctor if you have rectal bleeding or fail to have a bowel movement after use of a laxative. These could be signs of a serious condition. you need to use a laxative for more than 1 week If pregnant or breast-feeding ask a health professional before use.
Keep out of reach of children. In case of overdose, get medical help or contact a Poison Control Center (1-800-222-1222) right away.
📦 Storage and Handling ▾
Other information each softgel contains: sodium 13 mg store between 20-25ºC(68-77ºF); excursions permitted between 15-30ºC (59-86ºF)
🧪 Active Ingredient ▾
Active ingredient (in each softgel) Docusate sodium 250 mg
🧪 Inactive Ingredients ▾
Inactive Ingredients anhydrous citric acid, FD&C red #40, FD&C yellow #6, gelatin, glycerin, isopropyl alcohol, lecithin, mannitol, mineral oil, polyethylene glycol, propylene glycol, purified water, sorbitan, sorbitol, white ink
🎯 Purpose ▾
Purpose Stool softener laxative
No label section mentions that — try another word, or open the full label on DailyMed below.
Source: FDA Structured Product Labeling, mirrored from DailyMed / openFDA.
Prefer the government’s original formatting? View this label on DailyMed ↗
For educational and professional reference only — not medical advice. Pricing reflects published
NADAC and CMS ASP (free public data) and may differ from your acquisition cost; always verify before billing or dispensing.