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Amitriptyline Hydrochloride 10 mg Tablet, Film Coated, 1,000-count — NDC 16729-171-17 (Billing 16729-0171-17)

by Accord Healthcare Inc. · 1000 TABLET, FILM COATED in 1 BOTTLE

This is a package of 1,000 tablets of Amitriptyline Hydrochloride 10 mg Tablet, Film Coated from Accord Healthcare Inc., marketed since Dec 2014 and currently FDA-listed; retail pharmacies pay about $0.0404 per tablet (NADAC).

NDC 16729-0171-17
🏷️ FDA NDC (as labeled) 16729-171-17 billing pads the product segment with a zero
This package
Contains1,000-count Cost per ea$0.0404 NADAC Per package$40.40 / 1000 tablets Pack sizes2 compare ↓
Also priced by: Medicaid pays $0.2281/unit — full pricing hub ↓
Product page 16729-0171-01 Also comes in: 100 tablets 16729-171-01
Rx only Generic On market Non-controlled ⇄ Compare with another NDC
🗂️ FDA directory synced Oct 8, 2026 · this listing last changed Oct 8, 2026 · sources: openFDA · FDA label (DailyMed) · FDA Orange & Purple Book · First Databank · CMS NADAC, ASP, Medicare & Medicaid · RxNorm
📋 All sources & update times →

This page is curated, coded, and maintained by

Compiled from public FDA, CMS, DailyMed, NADAC, and related drug data sources. Editorial policy

NDC database record

One package, one record: these facts belong to NDC 16729-171-17 alone.

Record
FDA NDC Directory package listing · Human prescription drug
Code segments
16729 labeler · 171 product · 17 package
Package marketed since
Dec 5, 2014
Sample package
No — commercial package
Listing certified through
Dec 31, 2026
Billing quantity
1,000 EA per package
Barcode (UPC-A, from the NDC)
3 1672917117 5
Medicaid fills, this package
75 prescriptions in the last four reported quarters
FDA record last changed
Oct 8, 2026

Identity & classification

Regulatory identifiers FDA, NLM and CMS codes for this package

FDA NDC (as labeled) 16729-171-17
Product NDC 16729-171
11-digit billing NDC 16729017117
NCPDP billing unit EA — each (per item)
Application # ANDA202446
SPL Set ID 387e8b29-cf4d-4859-e063-6294a90ad470
Established class (EPC) Tricyclic Antidepressant
DEA schedule Non-controlled
Marketing category ANDA
Marketing status On market
FDA listing status Listed (active directory)
Marketing start 2014-12-05
Route ORAL
Dosage form TABLET, FILM COATED
Substance AMITRIPTYLINE HYDROCHLORIDE
TE code (Orange Book) AB · RLD · RS

Drug-database identifiers Medi-Span GPI and First Databank GCN / HICL / AHFS classification

GPI-14 58200010100305
GPI class Amitriptyline HCl
GCN Seq No 046043
GCN 16512
HICL code 001643
Ingredient (HICL) Amitriptyline Hcl
HIC1 code H
Therapeutic class — broad (HIC1) Nervous System (Except Autonomic)
HIC2 code H2
Therapeutic class — intermediate (HIC2) Psychoactive Drugs
HIC3 code H2U
Therapeutic class — specific (HIC3) Tricyclic Antidepressants,Rel.non-Sel.reupt-Inhib
AHFS code 28:16.04.28
AHFS class Tricyclics, Other Norepi-Ru Inhibitors
FDB label name AMITRIPTYLINE HCL 10 MG TAB
FDB brand name Amitriptyline Hcl
Legend status F — Federal legend — prescription drug or device
Quick answers
  • GSN (GCN sequence number): 046043
  • GCN: 16512
  • GPI-14 (Medi-Span): 58200010100305
  • HICL (First Databank): 001643
  • AHFS class code: 28:16.04.28
Why two NDCs? The FDA registers this code as 16729-171-17 — a 5-3-2 layout, and that's what's printed on the package and shown on DailyMed. For insurance claims, every NDC is standardized to a uniform 11-digit 5-4-2 format by adding a zero to the product segment → 16729-0171-17. Same drug, same package — only the format differs.
Where does this data come from?
Identifiers from the FDA openFDA NDC Directory and Structured Product Labeling; RxCUI from RxNorm (NLM); GPI from Medi-Span; GCN / HIC / AHFS / legend from First Databank.

Clinical

Label name AMITRIPTYLINE HCL 10 MG TAB Ingredient Amitriptyline Hcl
📗 Our plain-language guide HelloPharmacist
  • It's used to relieve symptoms of depression. It tends to work best for endogenous depression. Your prescriber can explain why it was chosen for you.
  • You may feel sleepy before your mood improves. Full benefit can take as long as 30 days. Keep taking it as directed and keep in touch with your prescriber.
  • It's taken by mouth, and your prescriber may split the dose or have you take it at bedtime. It can make you drowsy, so bedtime dosing is common. Follow your label directions.
  • Please don't stop suddenly. After long use, stopping abruptly can cause nausea, headache and malaise. Your prescriber will lower the dose gradually and often continues treatment fo...
📖 Read our full Amitriptyline guide →

Supplement & herbal interactions

🌿 Drug–supplement interaction checker →
3
Nutrient depletion considerations

Amitriptyline may be associated with lower levels of 3 nutrients — worth a chat with your pharmacist, not a cause for alarm.

🧪 Full Amitriptyline nutrient depletion report →
An association is not a deficiency. Educational only — don't start or stop anything without professional guidance.
Where does this data come from?
Plain-language summary from MedlinePlus (U.S. National Library of Medicine); supplement & herbal interactions and nutrient depletion data from the Natural Medicines database; our full guide is HelloPharmacist editorial content.

Pricing

A drug doesn't have one price. Each row is a different public payment system, and none is what you'd pay at the counter — that depends on your insurance. The ⓘ on each row explains what it measures.

Price systemPer eaPer package
Retail pharmacies payNADAC · weekly $0.040 $40.40 / 1000 tablets
Medicaid paysCMS SDUD · 12 mo $0.2281 $228.10 / 1000 tablets
Medicare drug plans payPart D · quarterly No Part D plan price is available for this NDC in our data.
NADAC price history (per ea) — tap or hover for the price & month
Dec 2021 Apr 2022 Sep 2022 Feb 2024 $0.048 $0.036
▼ Down 15% over the last 15 months.
Where does this data come from?
NADAC (National Average Drug Acquisition Cost) is the CMS weekly pharmacy-acquisition-cost survey — what pharmacies pay. ASP (Average Sales Price) is the CMS Medicare Part B drug-payment file, published quarterly. Medicaid pays is computed by us from CMS State Drug Utilization Data (total reimbursed ÷ units, trailing 12 months) — gross of rebates and inclusive of dispensing fees, so it reflects what Medicaid paid, not an acquisition cost. Medicare drug plans pay is the median negotiated point-of-sale unit cost across plans listing this NDC in the CMS quarterly Prescription Drug Plan pricing files, before rebates. The VA pays is the federal contract price (FSS, and the statutory Big 4 ceiling where listed) from the VA National Acquisition Center pharmaceutical price file. All are free public government data; each measures a different payer, so the figures are not directly comparable.

Packaging — all sizes for this product

Package NDCDescription Per unit Per pack Marketing startMarketing endStatus
16729-0171-01 16729-171-01 Main listing 100 TABLET, FILM COATED in 1 BOTTLE $0.0320 / ea $3.20 2014-12-18 — Active
16729-0171-17 You're viewing this 1000 TABLET, FILM COATED in 1 BOTTLE $0.0404 / ea $40.41 2014-12-05 — Active

You're viewing the largest of 2 pack sizes for this product.

Per ea, this pack runs about 26% above the cheapest pack (100-count, $0.0320 vs $0.0404 NADAC).

This pack accounts for about 3.0% of this product's recent Medicaid fills; most go to the 100 tablets pack. See all packs ↓

Pack size FAQ

What quantity is in this package?
This is a 1,000-count package — 1000 tablet, film coated in 1 bottle.
How does this package differ from NDC 16729-0171-01?
Both are Amitriptyline Hydrochloride 10 mg Tablet, Film Coated — the drug itself is identical. This page's package is the 1,000-count one, while NDC 16729-0171-01 is the 100 tablets package. Per-ea NADAC also differs: $0.0404 here vs $0.0320 for the 100 tablets pack.
What NDC number is used to bill for this package of Amitriptyline Hydrochloride 10 mg Tablet, Film Coated?
Use the 11-digit billing form listed in the identifiers section of this page. Pharmacy and medical claims use the 11-digit form; the FDA label may print a shorter form of the same code.

Prices are the latest CMS NADAC pharmacy acquisition cost per NDC; per-pack figures are per-unit × pack quantity, shown only when the pack is denominated in the same measure NADAC prices.

Therapeutic equivalents

ProductLabelerPackNADAC/unitTEStatusPrice vs. this
Amitriptyline Hydrochloride 10 mg 00781-1486-01 Sandoz 100 tablets $0.030 AB Availability likely save 26%
Amitriptyline Hydrochloride 10 mg 11788-0077-01 AiPing 100 tablets $0.030 AB Availability likely save 26%
Amitriptyline Hydrochloride 10 mg 16571-0105-01 Rising 100 tablets $0.030 AB Availability likely save 26%
Amitriptyline Hydrochloride 10 mg 16714-0257-01 Northstar 100 tablets $0.030 AB Availability likely save 26%
Amitriptyline Hydrochloride 10 mg 29300-0419-01 Unichem 100 tablets $0.030 AB Availability likely save 26%
Amitriptyline Hydrochloride 10 mg 50268-0037-15 AvPAK 1 tablet $0.030 AB Availability likely save 26%
Amitriptyline Hydrochloride 10 mg 57664-0687-18 Sun 1000 tablets $0.030 AB Availability likely save 26%
Amitriptyline Hydrochloride 10 mg 69367-0388-01 Westminster 100 tablets $0.030 AB Availability likely save 26%
Amitriptyline Hydrochloride 10 mg 70710-1225-00 Zydus 1000 tablets $0.030 AB Availability likely save 26%
Amitriptyline Hydrochloride 10 mg 70756-0201-11 Lifestar 100 tablets $0.030 AB Availability likely save 26%
Amitriptyline Hydrochloride 10 mg 72888-0067-00 Advagen 1000 tablets $0.030 AB Availability likely save 26%
Amitriptyline Hydrochloride 10 mgthis 16729-0171-17 Accord 1000 tablets $0.040 AB FDA listed —
Amitriptyline Hydrochloride 10 mg 50090-6179-00 A-S 30 tablets — AB FDA listed —
Amitriptyline Hydrochloride 10 mg 50090-7424-00 A-S 30 tablets — AB FDA listed —
Amitriptyline Hydrochloride 10 mg 51407-0793-01 Golden 100 tablets — AB FDA listed —
Amitriptyline Hydrochloride 10 mg 51655-0084-26 Northwind 90 tablets — AB FDA listed —
Amitriptyline Hydrochloride 10 mg 51655-0632-26 Northwind 90 tablets — AB FDA listed —
Amitriptyline Hydrochloride 10 mg 60760-0556-15 St. 15 tablets — AB FDA listed —
Amitriptyline Hydrochloride 10 mg 63187-0637-30 Proficient 30 tablets — AB FDA listed —
Amitriptyline Hydrochloride 10 mg 64330-0630-01 Centaur 100 tablets — — FDA listed —
Amitriptyline Hydrochloride 10 mg 68071-3913-03 NuCare 30 tablets — AB FDA listed —
Amitriptyline Hydrochloride 10 mg 68071-4092-02 NuCare 20 tablets — AB FDA listed —
Amitriptyline Hydrochloride 10 mg 68071-4104-01 NuCare 100 tablets — AB FDA listed —
Amitriptyline Hydrochloride 10 mg 68788-8218-03 Preferred 30 tablets — AB FDA listed —
Amitriptyline Hydrochloride 10 mg 70518-3621-00 REMEDYREPACK 30 tablets — AB FDA listed —
Amitriptyline Hydrochloride 10 mg 70518-4234-00 REMEDYREPACK 60 tablets — AB FDA listed —
Amitriptyline Hydrochloride 10 mg 70771-1173-00 Zydus 1000 tablets — AB FDA listed —
Amitriptyline Hydrochloride 10 mg 71335-0395-00 Bryant 100 tablets — AB FDA listed —
Amitriptyline Hydrochloride 10 mg 71335-3007-00 Bryant 100 tablets — AB FDA listed —
Amitriptyline Hydrochloride 10 mg 71335-9637-00 Bryant 100 tablets — AB FDA listed —
Amitriptyline Hydrochloride 10 mg 71610-0710-30 Aphena 30 tablets — AB FDA listed —
Amitriptyline Hydrochloride 10 mg 71610-0750-30 Aphena 30 tablets — AB FDA listed —
Amitriptyline HCL 10 mg 72189-0431-90 Direct_Rx 90 tablets — AB FDA listed —
Amitriptyline Hydrochloride 10 mg 76420-0693-01 Asclemed 100 tablets — AB FDA listed —
Amitriptyline HCL 10 mg 80425-0172-01 Advanced 30 tablets — AB FDA listed —
Amitriptyline Hydrochloride 10 mg 80425-0386-01 Advanced 30 tablets — AB FDA listed —
Amitriptyline Hydrochloride 10 mg 82804-0092-30 Proficient 30 tablets — AB FDA listed —
Amitriptyline Hydrochloride 10 mg 82868-0093-90 Northwind 90 tablets — AB FDA listed —
About this product: this is a generic version of the medicine. FDA equivalence ratings are shown when available, and other versions are listed above, least expensive first.
Where does this data come from?
Equivalents are other NDCs of the same ingredient, form and route from the openFDA NDC Directory, ranked least-expensive-first by NADAC. Therapeutic-equivalence (AB) ratings come from the FDA Orange Book; biologics use the FDA Purple Book for biosimilar & interchangeable status.

Availability & generic status

🏛️
2014
On the market since
Dec 2014
📍
2026
Currently FDA-listed
12 years listed
🔓
·
Generic on the market
this product is a generic
✅This is a generic drug

This product is an FDA-approved generic. Other versions of the same drug are listed under Therapeutic equivalents, least expensive first.

Where does this data come from?
Patents and exclusivity from the FDA Orange Book (small-molecule drugs), refreshed from public FDA data. Generic launch timing is an estimate, not a guarantee.

Inactive Ingredients / Excipients

Inactive ingredients, also called excipients, are components of the drug product other than the active ingredient. They may include fillers, dyes, coatings, preservatives, flavors, or other formulation ingredients.

🧪 Avoiding an ingredient? See Amitriptyline inactive ingredients by manufacturer: every current product's list side by side, so you can ask your pharmacy for the version that does not list it.

Loading inactive ingredients from the official FDA label in the background. No external source is being called by this page request.
Where does this data come from?
Source: official FDA Structured Product Labeling (SPL) via DailyMed and the openFDA label index. Structured IACT rows and label-wide narrative are kept separate; availability and product-level specificity depend on the submitted label.

Inactive ingredient FAQ

Are inactive ingredients the same for every manufacturer?
No. Inactive ingredients can differ by manufacturer, dosage form, strength, and package / product version.
Why might an inactive ingredient be missing?
Some SPLs do not provide a complete structured inactive-ingredient list, and older or unusual labels may only include the information in narrative text.
Can inactive ingredients matter?
Yes. They can matter for allergies, intolerances, dyes, gluten / lactose concerns, preservatives, and formulation differences — but confirm with a pharmacist or the manufacturer when it’s clinically important.

Manufacturer & labeler

LabelerAccord Healthcare Inc.
Application holderACCORD HEALTHCARE INC
FDA applicationANDA202446 (ANDA)
Labeler code16729
First marketedDec 2014
Product typeHuman Prescription Drug
Portfolio143 products on file

More NDCs from Accord Healthcare Inc. labeler code 16729

The labeler markets the product; the application holder owns the FDA approval. They’re often the same company but can differ (e.g. a repackager or an authorized generic). A mailing address / phone appears here when the manufacturer includes it in the product’s FDA label (not all do).
Where does this data come from?
Labeler, application holder and registered establishment from the FDA openFDA NDC Directory and Drugs@FDA; address/contact from the product’s FDA label.

Full prescribing information FDA SPL

The complete FDA label for this product — the official prescribing information, verbatim, section by section. Jump with a chip, search within the label, or expand everything.
📄 FDA label
📄 FDA label 19 words ▾

No FDA label is on file for this product yet. Labels load from openFDA / DailyMed and refresh weekly.

Source: FDA Structured Product Labeling, mirrored from DailyMed / openFDA. Prefer the government’s original formatting? View this label on DailyMed ↗

Medicaid utilization & spend

📍 This exact package only: Medicaid data is reported per full 11-digit NDC — labeler, product and pack size — so every number here is for this package alone, not the drug overall. Other pack sizes report separately.
💊 Pharmacy benefit only: These are Medicaid outpatient pharmacy claims, billed by NDC. They exclude the medical benefit — clinic- or hospital-administered drugs billed under HCPCS J-codes — so drugs used mostly that way (e.g. Avastin, Lucentis, Keytruda) can look low or missing here. That’s expected, not an error.
📅 Q1 2025 – Q1 2026 · 5 quarters of data
ⓘ The newest quarter is usually incomplete when first published; states restate recent quarters in later CMS releases, so the latest figures typically revise upward. State coverage-policy changes can also shift quarter-to-quarter totals.
Prescriptions last 4 qtrs
75
Units reimbursed last 4 qtrs
3K
Gross reimbursed last 4 qtrs
$678.65
Avg / prescription
$9.05
Avg / unit
$0.2281
Latest quarter Q1 2026
0Rx
Medicaid pays / ea
$0.2281
gross reimbursed
vs
NADAC / ea
$0.0404
acquisition cost
=
Spread
+$0.1877
+465% vs cost
What Medicaid paid per ea (before rebates; includes the pharmacy’s dispensing fee) compared with NADAC — the average price pharmacies pay to buy the drug. A positive spread means Medicaid reimbursed more than the purchase price, before manufacturer rebates.
Fee-for-service vs managed care ⓘ
36% FFS 64% MCO
Fee-for-service · 27 Rx Managed care · 48 Rx
State Medicaid map
Alaska: no data reported AK Maine: no data reported ME Washington: no data reported WA Idaho: no data reported ID Montana: no data reported MT North Dakota: no data reported ND Minnesota: no data reported MN Wisconsin: no data reported WI Michigan: no data reported MI New York: no data reported NY Vermont: no data reported VT New Hampshire: no data reported NH Oregon: no data reported OR Nevada: no data reported NV Wyoming: no data reported WY South Dakota: no data reported SD Iowa: no data reported IA Illinois: no data reported IL Indiana: no data reported IN Ohio: no data reported OH Pennsylvania: no data reported PA New Jersey: no data reported NJ Massachusetts: no data reported MA California: no data reported CA Utah: no data reported UT Colorado: no data reported CO Nebraska: no data reported NE Missouri: no data reported MO Kentucky: no data reported KY West Virginia: no data reported WV Virginia: 1,235 units · 14.2 per 100k residents VA Maryland: no data reported MD Connecticut: no data reported CT Rhode Island: no data reported RI Arizona: no data reported AZ New Mexico: no data reported NM Kansas: no data reported KS Arkansas: no data reported AR Tennessee: no data reported TN North Carolina: no data reported NC South Carolina: no data reported SC Delaware: no data reported DE Oklahoma: no data reported OK Louisiana: no data reported LA Mississippi: no data reported MS Alabama: no data reported AL Georgia: 1,740 units · 15.8 per 100k residents GA D.C.: no data reported DC Hawaii: no data reported HI Texas: no data reported TX Florida: no data reported FL
Units reimbursed · per 100k residents
14.215.8
gray = no data reported ⓘ
Colors are per 100,000 residents, so big states don’t automatically dominate. Tap or hover a state for its actual totals.
Tap or hover a state
…for its Medicaid breakdown
🏆 Top states by units · per 100k residents
1 Georgia 15.8 /100k
2 Virginia 14.2 /100k
National units — by quarter
💵 About the dollar figures: “reimbursed” is what Medicaid paid pharmacies before confidential manufacturer rebates, so the program’s real net cost is lower than these numbers. Fee-for-service and managed-care claims are combined unless split above. Source: CMS State Drug Utilization Data; per-100k rates use 2023 Census population estimates.

Medicaid utilization by pack size

Medicaid (SDUD) totals over the four most recent reported quarters for every package size of this drug — handy when a specific package (e.g. a starter/titration pack) carries little or no Medicaid volume on its own.
100 tablets16729-0171-01 2,436 Rx · $23,916
1000 tablets this page16729-0171-17 75 Rx · $679
Drug total (last 4 qtrs): 2,511 Rx · 109,263 units · $24,594 gross reimbursed
Tap a pack size to open its page. Source: CMS State Drug Utilization Data, last 4 quarters.
← 16729-0170-01 · Accord 16729-0175-01 · Accord →
For educational and professional reference only — not medical advice. Pricing reflects published NADAC and CMS ASP (free public data) and may differ from your acquisition cost; always verify before billing or dispensing.