Medique Medi-Seltzer Pain Relief Aspifin 325 mg Tablet, Effervescent
by Unifirst First Aid Corporation · 18 PACKET in 1 BOX, UNIT-DOSE (47682-147-20) / 2 TABLET, EFFERVESCENT in 1 PACKET
NDC 47682-0147-20
🏷️ FDA NDC (as labeled)
47682-147-20
billing pads the product segment with a zero
This package
Contains2 tablet, effervescent in 1 packet
Pack sizes2 compare ↓
Also comes in:
2 tablets 47682-0147-24
OTC
On market
Non-controlled
🗂️ Data synced Jul 24, 2026 · sources: openFDA · FDA label (DailyMed) · FDA Orange & Purple Book · First Databank · CMS NADAC, ASP, Medicare & Medicaid · RxNorm
📋 All sources & update times →
🆔 Identity & classification
FDA NDC (as labeled)
47682-147-20
Product NDC
47682-147
11-digit billing NDC
47682014720
RxCUI
2606079
UNII
R16CO5Y76E
UPC
0347682165345
Application #
M013
SPL Set ID
3d593dee-b932-b611-e063-6294a90ad3b7
Established class (EPC)
Nonsteroidal Anti-inflammatory Drug; Platelet Aggregation Inhibitor
Mechanism of action
Cyclooxygenase Inhibitors
Physiologic effect
Decreased Prostaglandin Production; Decreased Platelet Aggregation
Chemical class
Anti-Inflammatory Agents, Non-Steroidal
DEA schedule
Non-controlled
Marketing category
OTC MONOGRAPH DRUG
Marketing status
On market
FDA listing status
Listed (active directory)
Marketing start
2025-03-17
Route
ORAL
Dosage form
TABLET, EFFERVESCENT
Substance
ASPIRIN
Why two NDCs?
The FDA registers this code as 47682-147-20 — a 5-3-2 layout, and that's what's printed on the package and shown on DailyMed. For insurance claims, every NDC is standardized to a uniform 11-digit 5-4-2 format by adding a zero to the product segment → 47682-0147-20. Same drug, same package — only the format differs.
Where does this data come from?
Identifiers from the FDA openFDA NDC Directory and Structured Product Labeling; RxCUI from RxNorm (NLM); GPI from Medi-Span; GCN / HIC / AHFS / legend from First Databank.
🏷️ RxNorm drug class
This medicine belongs to the Platelet Aggregation Inhibitor class.
Pharmacologic class
Platelet Aggregation Inhibitor, Nonsteroidal Anti-inflammatory Drug
Drug family (ATC)
Other agents for local oral treatment, Platelet aggregation inhibitors excl. heparin, Salicylic acid and derivatives
How it works
Cyclooxygenase Inhibitors
Where does this data come from?
Therapeutic classes from RxNorm RxClass (U.S. National Library of Medicine) — Established Pharmacologic Class (FDA), ATC drug family (WHO) and mechanism of action, matched by this product’s RxCUI.
🏭 Manufacturer & labeler
LabelerUnifirst First Aid Corporation
FDA applicationM013 (OTC MONOGRAPH DRUG)
Labeler code47682
First marketedMar 2025
Product typeHuman Otc Drug
Portfolio183 products on file
The labeler markets the product; the application holder owns the FDA approval. They’re often the same company but can differ (e.g. a repackager or an authorized generic). A mailing address / phone appears here when the manufacturer includes it in the product’s FDA label (not all do).
Where does this data come from?
Labeler, application holder and registered establishment from the FDA openFDA NDC Directory and Drugs@FDA; address/contact from the product’s FDA label.
🩺 Clinical
📗 Our plain-language guide HelloPharmacist
- Aspirin is used to temporarily relieve common minor pains — things like headaches, backaches, muscle aches, toothaches, menstrual cramps, and discomfort from a cold — and to reduce...
- Generally, no — aspirin should not be given to children under 12. More importantly, children and teenagers who have or are recovering from chickenpox or a flu-like illness should n...
- Yes, stomach upset, heartburn, and nausea are real possibilities with aspirin. Taking it with a full glass of water helps. Some people tolerate enteric-coated or delayed-release fo...
- Does aspirin upset your stomach? What can I do about it?
Patient education
Supplement & herbal interactions
Where does this data come from?
Plain-language summary from MedlinePlus (U.S. National Library of Medicine); supplement & herbal interactions and nutrient depletion data from the Natural Medicines database; our full guide is HelloPharmacist editorial content.
💬 Questions about Aspifin?
Ask a pharmacist →
Ask a licensed pharmacist directly — free, answered by our team.
🧪 Inactive Ingredients / Excipients
Inactive ingredients, also called excipients, are components of the drug product other than the active ingredient. They may include fillers, dyes, coatings, preservatives, flavors, or other formulation ingredients.
Loading inactive ingredients from the official FDA label in the background. No external source is being called by this page request.
Where does this data come from?
Source: official FDA Structured Product Labeling (SPL) via DailyMed and the openFDA label index. Structured
IACT rows and label-wide narrative are kept separate; availability and product-level specificity depend on the submitted label.Inactive ingredient FAQ
Are inactive ingredients the same for every manufacturer?
No. Inactive ingredients can differ by manufacturer, dosage form, strength, and package / product version.
Why might an inactive ingredient be missing?
Some SPLs do not provide a complete structured inactive-ingredient list, and older or unusual labels may only include the information in narrative text.
Can inactive ingredients matter?
Yes. They can matter for allergies, intolerances, dyes, gluten / lactose concerns, preservatives, and formulation differences — but confirm with a pharmacist or the manufacturer when it’s clinically important.
💲 Pricing
A drug doesn't have one price. Each row is a different public payment system, and none is what you'd pay at the counter — that depends on your insurance. The ⓘ on each row explains what it measures.
| Price system | Per each | Per package |
|---|---|---|
| Retail pharmacies payNADAC · weekly | Not in the retail survey — common for institutional, discontinued, or low-volume packs. | |
| Medicaid paysCMS SDUD · 12 mo | No recent Medicaid claims on file for this NDC — rare and low-volume NDCs are suppressed in the public data. | |
| Medicare drug plans payPart D · quarterly | No Part D plan price is available for this NDC in our data. | |
ℹ️
No price is published for this exact package yet. CMS surveys NADAC per package size, so a different pack of the same drug often has one.
Try another pack size:
2 tablets
Where does this data come from?
NADAC (National Average Drug Acquisition Cost) is the CMS weekly pharmacy-acquisition-cost survey — what pharmacies pay. ASP (Average Sales Price) is the CMS Medicare Part B drug-payment file, published quarterly. Medicaid pays is computed by us from CMS State Drug Utilization Data (total reimbursed ÷ units, trailing 12 months) — gross of rebates and inclusive of dispensing fees, so it reflects what Medicaid paid, not an acquisition cost. Medicare drug plans pay is the median negotiated point-of-sale unit cost across plans listing this NDC in the CMS quarterly Prescription Drug Plan pricing files, before rebates. The VA pays is the federal contract price (FSS, and the statutory Big 4 ceiling where listed) from the VA National Acquisition Center pharmaceutical price file. All are free public government data; each measures a different payer, so the figures are not directly comparable.
🔁 Therapeutic equivalents
| Product | Labeler | Pack | NADAC/unit | TE | Status | Price vs. this |
|---|---|---|---|---|---|---|
| Alka-Seltzer Original Flavor 325 mg 00280-0087-02 | Bayer | 2 tablets | — | — | FDA listed | — |
| Alka-Seltzer Pain Relief 325 mg 00280-8251-24 | Bayer | 2 tablets | — | — | FDA listed | — |
| Signature Select Effervescent Pain Relief 325 mg 21130-0295-36 | Safeway | 2 tablets | — | — | FDA listed | — |
| TopCare Effervescent Pain Relief 325 mg 36800-0789-36 | TOPCO | 2 tablets | — | — | FDA listed | — |
| HEB Effervescent Pain Relief 325 mg 37808-0861-36 | H. | 2 tablets | — | — | FDA listed | — |
| Equaline Effervescent Pain Reliever 325 mg 41163-0741-36 | UNITED | 2 tablets | — | — | FDA listed | — |
| Medique Medi-Seltzer Pain Relief 325 mgthis 47682-0147-20 | Unifirst | 2 tablets | — | — | FDA listed | — |
| Good Sense Effervescent Pain Relief 325 mg 50804-0422-36 | Perrigo | 2 tablets | — | — | FDA listed | — |
| CVS Effervescent Pain Reliever 325 mg 51316-0359-36 | CVS | 2 tablets | — | — | FDA listed | — |
| Market Basket Effervescent Pain Relief 325 mg 53942-0883-36 | DEMOULAS | 2 tablets | — | — | FDA listed | — |
| Drug Mart Effervescent Pain Relief 325 mg 53943-0431-36 | Discount | 2 tablets | — | — | FDA listed | — |
| Family Wellness Pain Reliever 325 mg 55319-0870-36 | FAMILY | 2 tablets | — | — | FDA listed | — |
| Dollar General Effervescent Pain Reliever 325 mg 55910-0040-36 | Dolgencorp, | 2 tablets | — | — | FDA listed | — |
| Publix Fast Relief Effervescent - Original Flavor 325 mg 56062-0358-36 | PUBLIX | 2 tablets | — | — | FDA listed | — |
| Best Choice Effervescent Pain Reliever 36 325 mg 63941-0241-12 | VALU | 2 tablets | — | — | FDA listed | — |
| Alka-Seltzer 325 mg 66715-5206-00 | Lil' | 2 tablets | — | — | FDA listed | — |
| Alka-Seltzer Original Flavor 325 mg 66715-6403-02 | Lil' | 2 tablets | — | — | FDA listed | — |
| Alka-Seltzer Original Flavor 325 mg 66715-6503-02 | Lil' | 2 tablets | — | — | FDA listed | — |
| Alka-Seltzer Original Flavor 325 mg 66715-9603-02 | Lil' | 2 tablets | — | — | FDA listed | — |
| Winco Foods Effervescent Pain Relief 325 mg 67091-0448-36 | Winco | 2 tablets | — | — | FDA listed | — |
| Alka-Seltzer Original Flavor 325 mg 67751-0219-01 | Navajo | 2 tablets | — | — | FDA listed | — |
| Meijer Effervescent Pain Relief 325 mg 79481-0073-06 | Meijer | 2 tablets | — | — | FDA listed | — |
| Quality Choice Effervescent Pain Relief 325 mg 83324-0018-36 | CHAIN | 2 tablets | — | — | FDA listed | — |
About this product: other versions of the same ingredient, strength and form are listed above, least expensive first, with FDA equivalence ratings where available.
Where does this data come from?
Equivalents are other NDCs of the same ingredient, form and route from the openFDA NDC Directory, ranked least-expensive-first by NADAC. Therapeutic-equivalence (AB) ratings come from the FDA Orange Book; biologics use the FDA Purple Book for biosimilar & interchangeable status.
⏳ Availability & generic status
🏛️
2025
On the market since
Mar 2025
📍
2026
Currently FDA-listed
1 year listed
🔒
·
No generic listed yet
brand only
ℹ️No FDA-approved generic found
We did not find an FDA-approved generic match for this exact strength, form and route.
Where does this data come from?
Patents and exclusivity from the FDA Orange Book (small-molecule drugs), refreshed from public FDA data. Generic launch timing is an estimate, not a guarantee.
📦 Packaging — all sizes for this product
| Package NDC | Description | Marketing start | Status |
|---|---|---|---|
| 47682-0147-20 You're viewing this | 18 PACKET in 1 BOX, UNIT-DOSE (47682-147-20) / 2 TABLET, EFFERVESCENT in 1 PACKET | 2025-03-17 | Active |
| 47682-0147-24 | 36 PACKET in 1 BOX, UNIT-DOSE (47682-147-24) / 2 TABLET, EFFERVESCENT in 1 PACKET | 2025-03-17 | Active |
Pack size FAQ
What quantity is in NDC 47682-0147-20?
NDC 47682-0147-20 is listed by the FDA — 18 packet in 1 box, unit-dose / 2 tablet, effervescent in 1 packet.
What NDC number is used to bill for this package of Medique Medi-Seltzer Pain Relief Aspifin 325 mg Tablet, Effervescent?
Bill NDC 47682-0147-20 — the 11-digit billing format is 47682014720. Pharmacy and medical claims use the 11-digit form; the FDA label may print a shorter form of the same code.
🧭 About this NDC listing & data coverage
Over-the-counter (OTC) product
What data is (and isn’t) available for this NDC — tap to expand
| NDC identity (package / product / labeler codes) | ✓ Available |
| Labeler | ✓ Available |
| Product & package description | ✓ Available |
| Marketing category & status | ✓ Available |
| Active ingredient / dosage form / route | ✓ Available |
| FDA label (SPL via DailyMed) | ✓ Available |
| Package photos | — Not published for this NDC No photo available yet for this listing. |
| Inactive ingredients (structured) | — Not published for this NDC The labeler did not submit a structured excipient list, or no SPL is available. |
| NADAC pharmacy acquisition price (CMS) | — Not published for this NDC CMS publishes NADAC only for NDCs reported in its retail-pharmacy survey. |
| Orange Book / therapeutic-equivalence data | — Not published for this NDC Applies only to products approved under an NDA/ANDA; many listings are out of scope. |
| HCPCS J-code billing crosswalk | — Not published for this NDC Most self-administered / retail products have no J-code — that is normal. |
| Medicaid utilization (CMS SDUD) | — Not published for this NDC CMS reports utilization only for NDCs with Medicaid claims above its privacy threshold. |
“Not published” reflects what the public FDA / CMS / NLM sources provide for this exact package code — it is a property of the data feeds, not a judgment about the product.
Questions about this listing
Is this NDC FDA-approved?
An NDC listing does not by itself establish FDA approval — the NDC Directory records that a product is listed with FDA, not that it was reviewed and approved. This listing's marketing category is "Otc Monograph Drug". Products approved under an application carry an NDA, ANDA, or BLA number.
Why is there no price listed?
The pricing shown on our NDC pages comes from CMS NADAC, a voluntary survey of retail community pharmacy invoices. CMS does not publish a NADAC for every NDC — packages outside the retail survey (institutional and hospital products, bulk packages, discontinued items, and many OTC items) may never receive one. A missing price reflects the survey's scope, not this product's actual cost, and does not mean the product is free or unavailable.
Is the NDC printed on the package the same as the 11-digit billing NDC?
Yes, they identify this exact package in different formats. The FDA registers it as 47682-147-20, which is what is printed on the packaging and shown on DailyMed. Insurance claims use a fixed 11-digit 5-4-2 format, so the short segment is padded with a leading zero: 47682-0147-20, written without dashes as 47682014720. The Identity section at the top of this page lists every form of this code.
What do the three segments of this NDC mean?
In 47682-0147-20, the first segment (47682) is the labeler code FDA assigned to Unifirst First Aid Corporation; the middle segment (0147) identifies this specific product — its ingredient, strength, and dosage form; and the last segment (20) identifies this exact package size and type. Together they name one specific package of one specific product.
Is this package still being marketed?
Yes, per the latest FDA NDC Directory data on this page: this package is listed as actively marketed, with no marketing end date reported by Unifirst First Aid Corporation. Listing status can change — the directory data on this page refreshes weekly.
Does this product come in other package sizes?
Yes — the FDA directory lists 1 other package presentation of this same product, including 2 tablets (47682-0147-24). Each has its own NDC and its own page — see the package list near the top of this page.
Who lists this product with the FDA?
Unifirst First Aid Corporation is the labeler of record for this NDC — the company under whose FDA-assigned code the package is listed. The labeler may be the manufacturer itself or a distributor marketing the product under its own code.
Do I need a prescription for this product?
This NDC is listed with FDA as an over-the-counter product, so it does not require a prescription. Follow the package directions, and ask your pharmacist if you are unsure whether it is right for you.
This page identifies an FDA-listed package (the NDC) and reports public regulatory and pricing data about the listing. It is reference information, not a medical recommendation — talk to your pharmacist or prescriber about your own medication.
Where does this data come from?
Listing facts (marketing category, packager status, marketing dates) from the FDA openFDA NDC Directory; label availability from DailyMed; pricing coverage from CMS NADAC; equivalence scope from the FDA Orange Book.
📄 FDA label — Drug Facts FDA SPL
The complete FDA label for this product — the official Drug Facts labeling, verbatim, section by section. Jump with a chip, search within the label, or expand everything.
🎯 Indications and Usage
⏱️ Dosage and Administration
⚠️ Warnings
🧪 Active Ingredient
🧪 Inactive Ingredients
🎯 Purpose
🎯 Indications and Usage ▾
Uses for the temporary relief of minor aches and pains due to: headache muscle pain backache toothache menstrual pain colds minor arthritis pain temporarily reduces fever
⏱️ Dosage and Administration ▾
Directions do not exceed recommended dosage to avoid serious injury, completely dissolve tablets in 4 oz. of water before taking. Adults and children 12 years and over: 2 tablets every 4 hours, or as directed by a doctor. Do not exceed 8 tablets in 24 hours Adults 60 years and over: 2 tablets every 4 hours, or as directed by a doctor. Do not exceed 4 tablets in 24 hours Children under 12 years of age: Consult a doctor
⚠️ Warnings ▾
Warnings Reye's syndrome: Children and teenagers who have or are recovering from chicken pox or flu-like symptoms should not use this product. When using this product, if changes in behavior with nausea and vomiting occur, consult a doctor because these symptoms could be an early sign of Reye's syndrome, a rare but serious illness. Allergy Alert: Aspirin may cause a severe allergic reaction which may include: hives facial swelling asthma (wheezing) shock Stomach bleeding warning : This product contains an NSAID, which may cause severe stomach bleeding.
The chance is higher if you: are age 60 or older have had stomach ulcers or bleeding problems take a blood thinning (anticoagulant) or steroid drug take other drugs containing prescription or nonprescription NSAIDs (aspirin, ibuprofen, naproxen, or others) have 3 or more alcoholic drinks every day while using this product take more or for a longer time than directed
🧪 Active Ingredient ▾
Active Ingredients (in each effervescent tablet) Buffered aspirin 325 mg (NSAID)* *nonsteroidal anti-inflammatory drug
🧪 Inactive Ingredients ▾
Inactive ingredients : anhydrous citric acid, sodium bicarbonate
🎯 Purpose ▾
Purpose Pain Reliever / Fever Reducer
No label section mentions that — try another word, or open the full label on DailyMed below.
Source: FDA Structured Product Labeling, mirrored from DailyMed / openFDA.
Prefer the government’s original formatting? View this label on DailyMed ↗
For educational and professional reference only — not medical advice. Pricing reflects published
NADAC and CMS ASP (free public data) and may differ from your acquisition cost; always verify before billing or dispensing.