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Medique Medi-Seltzer Pain Relief Aspifin 325 mg Tablet, Effervescent — NDC 47682-0147-24 package photo
Label image from the product's FDA listing (DailyMed) — may show a different pack size or an older label revision.

Medique Medi-Seltzer Pain Relief Aspifin 325 mg Tablet, Effervescent — NDC 47682-147-24 (Billing 47682-0147-24)

by Unifirst First Aid Corporation · 36 PACKET in 1 BOX, UNIT-DOSE / 2 TABLET, EFFERVESCENT in 1 PACKET

This is a package of Medique Medi-Seltzer Pain Relief Aspifin 325 mg Tablet, Effervescent from Unifirst First Aid Corporation, marketed since Mar 2025 and currently FDA-listed.

NDC 47682-0147-24
🏷️ FDA NDC (as labeled) 47682-147-24 billing pads the product segment with a zero
This package
Contains2 tablet, effervescent in 1 packet Pack sizes2 compare ↓
Product page 47682-0147-20 Also comes in: 2 tablets 47682-147-20
OTC On market Non-controlled ⇄ Compare with another NDC
🗂️ FDA directory synced Oct 1, 2026 · this listing last changed Jul 24, 2026 · sources: openFDA · FDA label (DailyMed) · FDA Orange & Purple Book · First Databank · CMS NADAC, ASP, Medicare & Medicaid · RxNorm
📋 All sources & update times →

This page is curated, coded, and maintained by

Compiled from public FDA, CMS, DailyMed, NADAC, and related drug data sources. Editorial policy

NDC database record

One package, one record: these facts belong to NDC 47682-147-24 alone.

Record
FDA NDC Directory package listing · Human OTC drug
Code segments
47682 labeler · 147 product · 24 package
Package marketed since
Mar 17, 2025
Sample package
No — commercial package
Listing certified through
Dec 31, 2026
Barcode (UPC)
0347682165345
FDA record last changed
Jul 24, 2026

Identity & classification

Regulatory identifiers FDA, NLM and CMS codes for this package

FDA NDC (as labeled) 47682-147-24
Product NDC 47682-147
11-digit billing NDC 47682014724
RxCUI 2606079
UNII R16CO5Y76E
UPC 0347682165345
Application # M013
SPL Set ID 3d593dee-b932-b611-e063-6294a90ad3b7
Established class (EPC) Nonsteroidal Anti-inflammatory Drug; Platelet Aggregation Inhibitor
Mechanism of action Cyclooxygenase Inhibitors
Physiologic effect Decreased Prostaglandin Production; Decreased Platelet Aggregation
Chemical class Anti-Inflammatory Agents, Non-Steroidal
DEA schedule Non-controlled
Marketing category OTC MONOGRAPH DRUG
Marketing status On market
FDA listing status Listed (active directory)
Marketing start 2025-03-17
Route ORAL
Dosage form TABLET, EFFERVESCENT
Substance ASPIRIN
Quick answers
  • RxCUI (RxNorm): 2606079
Why two NDCs? The FDA registers this code as 47682-147-24 — a 5-3-2 layout, and that's what's printed on the package and shown on DailyMed. For insurance claims, every NDC is standardized to a uniform 11-digit 5-4-2 format by adding a zero to the product segment → 47682-0147-24. Same drug, same package — only the format differs.
Where does this data come from?
Identifiers from the FDA openFDA NDC Directory and Structured Product Labeling; RxCUI from RxNorm (NLM); GPI from Medi-Span; GCN / HIC / AHFS / legend from First Databank.

RxNorm drug class

This medicine belongs to the Platelet Aggregation Inhibitor class.

Pharmacologic class Platelet Aggregation Inhibitor, Nonsteroidal Anti-inflammatory Drug
Drug family (ATC) Other agents for local oral treatment, Platelet aggregation inhibitors excl. heparin, Salicylic acid and derivatives
How it works Cyclooxygenase Inhibitors
Where does this data come from?
Therapeutic classes from RxNorm RxClass (U.S. National Library of Medicine) — Established Pharmacologic Class (FDA), ATC drug family (WHO) and mechanism of action, matched by this product’s RxCUI.

Clinical

📗 Our plain-language guide HelloPharmacist
  • Aspirin is used to temporarily relieve common minor pains — things like headaches, backaches, muscle aches, toothaches, menstrual cramps, and discomfort from a cold — and to reduce...
  • Generally, no — aspirin should not be given to children under 12. More importantly, children and teenagers who have or are recovering from chickenpox or a flu-like illness should n...
  • Yes, stomach upset, heartburn, and nausea are real possibilities with aspirin. Taking it with a full glass of water helps. Some people tolerate enteric-coated or delayed-release fo...
  • Does aspirin upset your stomach? What can I do about it?
📖 Read our full Aspirin guide →

Supplement & herbal interactions

🌿 Drug–supplement interaction checker →
Where does this data come from?
Plain-language summary from MedlinePlus (U.S. National Library of Medicine); supplement & herbal interactions and nutrient depletion data from the Natural Medicines database; our full guide is HelloPharmacist editorial content.

Pricing

A drug doesn't have one price. Each row is a different public payment system, and none is what you'd pay at the counter — that depends on your insurance. The ⓘ on each row explains what it measures.

Price systemPer eachPer package
Retail pharmacies payNADAC · weekly Not in the retail survey — common for institutional, discontinued, or low-volume packs.
Medicaid paysCMS SDUD · 12 mo No recent Medicaid claims on file for this NDC — rare and low-volume NDCs are suppressed in the public data.
Medicare drug plans payPart D · quarterly No Part D plan price is available for this NDC in our data.
ℹ️
No price is published for this exact package yet. CMS surveys NADAC per package size, so a different pack of the same drug often has one.
Try another pack size: 2 tablets
Where does this data come from?
NADAC (National Average Drug Acquisition Cost) is the CMS weekly pharmacy-acquisition-cost survey — what pharmacies pay. ASP (Average Sales Price) is the CMS Medicare Part B drug-payment file, published quarterly. Medicaid pays is computed by us from CMS State Drug Utilization Data (total reimbursed ÷ units, trailing 12 months) — gross of rebates and inclusive of dispensing fees, so it reflects what Medicaid paid, not an acquisition cost. Medicare drug plans pay is the median negotiated point-of-sale unit cost across plans listing this NDC in the CMS quarterly Prescription Drug Plan pricing files, before rebates. The VA pays is the federal contract price (FSS, and the statutory Big 4 ceiling where listed) from the VA National Acquisition Center pharmaceutical price file. All are free public government data; each measures a different payer, so the figures are not directly comparable.

Packaging — all sizes for this product

Package NDCDescription Marketing startMarketing endStatus
47682-0147-20 47682-147-20 Main listing 18 PACKET in 1 BOX, UNIT-DOSE / 2 TABLET, EFFERVESCENT in 1 PACKET 2025-03-17 — Active
47682-0147-24 You're viewing this 36 PACKET in 1 BOX, UNIT-DOSE / 2 TABLET, EFFERVESCENT in 1 PACKET 2025-03-17 — Active

Pack size FAQ

What quantity is in this package?
This package is listed by the FDA — 36 packet in 1 box, unit-dose / 2 tablet, effervescent in 1 packet.
What NDC number is used to bill for this package of Medique Medi-Seltzer Pain Relief Aspifin 325 mg Tablet, Effervescent?
Use the 11-digit billing form listed in the identifiers section of this page. Pharmacy and medical claims use the 11-digit form; the FDA label may print a shorter form of the same code.

Therapeutic equivalents

ProductLabelerPackNADAC/unitTEStatusPrice vs. this
Alka-Seltzer Original Flavor 325 mg 00280-0087-02 Bayer 2 tablets — — FDA listed —
Alka-Seltzer Pain Relief 325 mg 00280-8251-24 Bayer 2 tablets — — FDA listed —
Signature Select Effervescent Pain Relief 325 mg 21130-0295-36 Safeway 2 tablets — — FDA listed —
TopCare Effervescent Pain Relief 325 mg 36800-0789-36 TOPCO 2 tablets — — FDA listed —
HEB Effervescent Pain Relief 325 mg 37808-0861-36 H. 2 tablets — — FDA listed —
Equaline Effervescent Pain Reliever 325 mg 41163-0741-36 UNITED 2 tablets — — FDA listed —
Medique Medi-Seltzer Pain Relief 325 mgthis 47682-0147-24 Unifirst 2 tablets — — FDA listed —
Good Sense Effervescent Pain Relief 325 mg 50804-0422-36 Perrigo 2 tablets — — FDA listed —
CVS Effervescent Pain Reliever 325 mg 51316-0359-36 CVS 2 tablets — — FDA listed —
Market Basket Effervescent Pain Relief 325 mg 53942-0883-36 DEMOULAS 2 tablets — — FDA listed —
Drug Mart Effervescent Pain Relief 325 mg 53943-0431-36 Discount 2 tablets — — FDA listed —
Family Wellness Pain Reliever 325 mg 55319-0870-36 FAMILY 2 tablets — — FDA listed —
Dollar General Effervescent Pain Reliever 325 mg 55910-0040-36 Dolgencorp, 2 tablets — — FDA listed —
Publix Fast Relief Effervescent - Original Flavor 325 mg 56062-0358-36 PUBLIX 2 tablets — — FDA listed —
Best Choice Effervescent Pain Reliever 36 325 mg 63941-0241-12 VALU 2 tablets — — FDA listed —
Alka-Seltzer 325 mg 66715-5206-00 Lil' 2 tablets — — FDA listed —
Alka-Seltzer Original Flavor 325 mg 66715-6403-02 Lil' 2 tablets — — FDA listed —
Alka-Seltzer Original Flavor 325 mg 66715-6503-02 Lil' 2 tablets — — FDA listed —
Alka-Seltzer Original Flavor 325 mg 66715-9603-02 Lil' 2 tablets — — FDA listed —
Winco Foods Effervescent Pain Relief 325 mg 67091-0448-36 Winco 2 tablets — — FDA listed —
Alka-Seltzer Original Flavor 325 mg 67751-0219-01 Navajo 2 tablets — — FDA listed —
Meijer Effervescent Pain Relief 325 mg 79481-0073-06 Meijer 2 tablets — — FDA listed —
Quality Choice Effervescent Pain Relief 325 mg 83324-0018-36 CHAIN 2 tablets — — FDA listed —
About this product: other versions of the same ingredient, strength and form are listed above, least expensive first, with FDA equivalence ratings where available.
Where does this data come from?
Equivalents are other NDCs of the same ingredient, form and route from the openFDA NDC Directory, ranked least-expensive-first by NADAC. Therapeutic-equivalence (AB) ratings come from the FDA Orange Book; biologics use the FDA Purple Book for biosimilar & interchangeable status.

Availability & generic status

🏛️
2025
On the market since
Mar 2025
📍
2026
Currently FDA-listed
1 year listed
🔒
·
No generic listed yet
brand only
ℹ️No FDA-approved generic found

We did not find an FDA-approved generic match for this exact strength, form and route.

Where does this data come from?
Patents and exclusivity from the FDA Orange Book (small-molecule drugs), refreshed from public FDA data. Generic launch timing is an estimate, not a guarantee.

What it looks like

Color white
ShapeRound
ImprintL421
Size25 mm
ScoringNot scored
One label can cover several strengths, so colors may be combined — always confirm a loose pill against the dispensed prescription label or a pharmacist.
Where does this data come from?
Physical description (imprint, shape, color, scoring, coating) from this product’s FDA Structured Product Labeling (SPL), mirrored from DailyMed / openFDA.

Inactive Ingredients / Excipients

Inactive ingredients, also called excipients, are components of the drug product other than the active ingredient. They may include fillers, dyes, coatings, preservatives, flavors, or other formulation ingredients.

🧪 Avoiding an ingredient? See Aspirin inactive ingredients by manufacturer: every current product's list side by side, so you can ask your pharmacy for the version that does not list it.

💡 Tap an ingredient (hover on desktop) to see what it is and why it’s used.

  • UNII 2968PHW8QP
    A weak organic acid derived from citrus fruits or made through fermentation. It works as a buffer to control pH, a preservative to extend shelf life, and a flavoring agent in medications.
  • UNII 8MDF5V39QO
    A white powder form of baking soda that acts as a buffer and pH regulator in medicines. It helps maintain the right acid-base balance and may aid tablet disintegration.

2 inactive ingredients listed in the exact product block matched to this NDC.

The official label also statesInactive ingredients: anhydrous citric acid, sodium bicarbonate

Label-section wording can be broader than the structured product block and may mention additional formulation ingredients.

Where does this data come from?
Data sourced from official FDA Structured Product Labeling (SPL) via DailyMed — ingredient classCode="IACT" elements from the exact product block matched by this NDC. Label-section narrative from DailyMed / the openFDA label index is shown separately when available.

Inactive ingredient FAQ

Are inactive ingredients the same for every manufacturer?
No. Inactive ingredients can differ by manufacturer, dosage form, strength, and package / product version.
Why might an inactive ingredient be missing?
Some SPLs do not provide a complete structured inactive-ingredient list, and older or unusual labels may only include the information in narrative text.
Can inactive ingredients matter?
Yes. They can matter for allergies, intolerances, dyes, gluten / lactose concerns, preservatives, and formulation differences — but confirm with a pharmacist or the manufacturer when it’s clinically important.

Manufacturer & labeler

LabelerUnifirst First Aid Corporation
FDA applicationM013 (OTC MONOGRAPH DRUG)
Labeler code47682
First marketedMar 2025
Product typeHuman Otc Drug
Portfolio183 products on file

More NDCs from Unifirst First Aid Corporation labeler code 47682

The labeler markets the product; the application holder owns the FDA approval. They’re often the same company but can differ (e.g. a repackager or an authorized generic). A mailing address / phone appears here when the manufacturer includes it in the product’s FDA label (not all do).
Where does this data come from?
Labeler, application holder and registered establishment from the FDA openFDA NDC Directory and Drugs@FDA; address/contact from the product’s FDA label.

FDA label — Drug Facts FDA SPL

The complete FDA label for this product — the official Drug Facts labeling, verbatim, section by section. Jump with a chip, search within the label, or expand everything.
🎯 Indications and Usage ⏱️ Dosage and Administration ⚠️ Warnings 🧪 Active Ingredient 🧪 Inactive Ingredients 🎯 Purpose 📄 Do Not Use 📄 Ask a Doctor Before Use If 📄 Ask a Doctor or Pharmacist Before Use If 📄 When Using This Product 📄 Stop Use and Ask a Doctor If 🤰 If Pregnant or Breast-Feeding 📄 Keep Out of Reach of Children 📄 Other Information 📄 Questions or Comments 📄 Package Label / Principal Display Panel
🎯 Indications and Usage 26 words ▾

Uses for the temporary relief of minor aches and pains due to: headache muscle pain backache toothache menstrual pain colds minor arthritis pain temporarily reduces fever

⏱️ Dosage and Administration 79 words ▾

Directions do not exceed recommended dosage to avoid serious injury, completely dissolve tablets in 4 oz. of water before taking. Adults and children 12 years and over: 2 tablets every 4 hours, or as directed by a doctor. Do not exceed 8 tablets in 24 hours Adults 60 years and over: 2 tablets every 4 hours, or as directed by a doctor. Do not exceed 4 tablets in 24 hours Children under 12 years of age: Consult a doctor

⚠️ Warnings 147 words ▾

Warnings Reye's syndrome: Children and teenagers who have or are recovering from chicken pox or flu-like symptoms should not use this product. When using this product, if changes in behavior with nausea and vomiting occur, consult a doctor because these symptoms could be an early sign of Reye's syndrome, a rare but serious illness. Allergy Alert: Aspirin may cause a severe allergic reaction which may include: hives facial swelling asthma (wheezing) shock Stomach bleeding warning : This product contains an NSAID, which may cause severe stomach bleeding.

The chance is higher if you: are age 60 or older have had stomach ulcers or bleeding problems take a blood thinning (anticoagulant) or steroid drug take other drugs containing prescription or nonprescription NSAIDs (aspirin, ibuprofen, naproxen, or others) have 3 or more alcoholic drinks every day while using this product take more or for a longer time than directed

🧪 Active Ingredient 14 words ▾

Active Ingredients (in each effervescent tablet) Buffered aspirin 325 mg (NSAID)* *nonsteroidal anti-inflammatory drug

🧪 Inactive Ingredients 8 words ▾

Inactive ingredients : anhydrous citric acid, sodium bicarbonate

🎯 Purpose 6 words ▾

Purpose Pain Reliever / Fever Reducer

📄 Do Not Use 32 words ▾

Do not use if you are allergic to aspirin or any other pain reliever/ fever reducer if you have ever had an allergic reaction to this product or any of its ingredients

📄 Ask a Doctor Before Use If 47 words ▾

Ask a doctor before use if stomach bleeding warning applies to you you have a history of stomach problems such as heartburn you have high blood pressure, heart disease, liver cirrhosis, or kidney disease you are taking a diuretic you have asthma you have a sodium-restricted diet

📄 Ask a Doctor or Pharmacist Before Use If 18 words ▾

Ask a doctor or pharmacist before use if you are taking a prescription drug for: diabetes gout arthritis

📄 When Using This Product 10 words ▾

When using this product do not take exceed recommended dosage

📄 Stop Use and Ask a Doctor If 81 words ▾

Stop use and ask a doctor if you experience any of the following signs of stomach bleeding you feel faint vomit blood have bloody or black stools have stomach pain that does not get better an allergic reaction occurs. Seek medical help right away pain lasts for more than 10 days or gets worse fever gets worse or lasts more than 3 days new symptoms appear redness or swelling is present ringing in the ears or a loss of hearing occurs

🤰 If Pregnant or Breast-Feeding 47 words ▾

If pregnant or breast-feeding, ask a health professional before use. It is especially important not to use aspirin at 20 weeks or later in pregnancy, unless definitely directed to do so by a doctor because it may cause problems in the unborn child or complications during delivery.

📄 Keep Out of Reach of Children 22 words ▾

Keep out of reach of children . In case of overdose, get medical help or contact a Poison Control Center right away.

📄 Other Information 30 words ▾

Other information each tablet contains: Sodium 524mg store at room temperature 59º-86º F (15º-30º C) avoid excessive heat. tamper evident sealed packets do not use any opened or torn packets

📄 Questions or Comments 4 words ▾

Questions or comments? 1-800-634-7680

📄 Package Label / Principal Display Panel 51 words ▾

Medique® Medi-Seltzer Pain Relief Effervescent Antacid / Pain Reliever Pull to Open This Package is for Households without Young Children. Aches, Fever ● Aspirin (NSAID) 325 mg Antacid ● Citric Acid 1000 mg Sodium Bicarbonate 1916 mg 36 Tablets (18 x 2) Tamper Evident Unit Dose Packets 125B MedSeltzerPain 12520 3-17-25

Source: FDA Structured Product Labeling, mirrored from DailyMed / openFDA. Prefer the government’s original formatting? View this label on DailyMed ↗

About this NDC listing & data coverage

Over-the-counter (OTC) product
What data is (and isn’t) available for this NDC — tap to expand
NDC identity (package / product / labeler codes) ✓ Available
Labeler ✓ Available
Product & package description ✓ Available
Marketing category & status ✓ Available
Active ingredient / dosage form / route ✓ Available
FDA label (SPL via DailyMed) ✓ Available
Package photos ✓ Available
Inactive ingredients (structured) ✓ Available
NADAC pharmacy acquisition price (CMS) — Not published for this NDC CMS publishes NADAC only for NDCs reported in its retail-pharmacy survey.
Orange Book / therapeutic-equivalence data — Not published for this NDC Applies only to products approved under an NDA/ANDA; many listings are out of scope.
HCPCS J-code billing crosswalk — Not published for this NDC Most self-administered / retail products have no J-code — that is normal.
Medicaid utilization (CMS SDUD) — Not published for this NDC CMS reports utilization only for NDCs with Medicaid claims above its privacy threshold.
“Not published” reflects what the public FDA / CMS / NLM sources provide for this exact package code — it is a property of the data feeds, not a judgment about the product.

Questions about this listing

Is this NDC FDA-approved?
An NDC listing does not by itself establish FDA approval — the NDC Directory records that a product is listed with FDA, not that it was reviewed and approved. This listing's marketing category is "Otc Monograph Drug". Products approved under an application carry an NDA, ANDA, or BLA number.
Why is there no price listed?
The pricing shown on our NDC pages comes from CMS NADAC, a voluntary survey of retail community pharmacy invoices. CMS does not publish a NADAC for every NDC — packages outside the retail survey (institutional and hospital products, bulk packages, discontinued items, and many OTC items) may never receive one. A missing price reflects the survey's scope, not this product's actual cost, and does not mean the product is free or unavailable.
Is the NDC printed on the package the same as the 11-digit billing NDC?
Yes, they identify this exact package in different formats. The form printed on the packaging and shown on DailyMed is the one the FDA registered. Insurance claims use a fixed 11-digit 5-4-2 format, so the short segment is padded with a leading zero and the dashes are dropped. The Identity section at the top of this page lists each form of this code.
Is this package still being marketed?
Yes, per the latest FDA NDC Directory data on this page: this package is listed as actively marketed, with no marketing end date reported by Unifirst First Aid Corporation. Listing status can change — the directory data on this page refreshes weekly.
Does this product come in other package sizes?
Yes — the FDA directory lists 1 other package presentation of this same product, including 2 tablets (47682-0147-20). Each has its own NDC and its own page — see the package list near the top of this page.
Who lists this product with the FDA?
Unifirst First Aid Corporation is the labeler of record for this NDC — the company under whose FDA-assigned code the package is listed. The labeler may be the manufacturer itself or a distributor marketing the product under its own code.
Do I need a prescription for this product?
This NDC is listed with FDA as an over-the-counter product, so it does not require a prescription. Follow the package directions, and ask your pharmacist if you are unsure whether it is right for you.
This page identifies an FDA-listed package (the NDC) and reports public regulatory and pricing data about the listing. It is reference information, not a medical recommendation — talk to your pharmacist or prescriber about your own medication.
Where does this data come from?
Listing facts (marketing category, packager status, marketing dates) from the FDA openFDA NDC Directory; label availability from DailyMed; pricing coverage from CMS NADAC; equivalence scope from the FDA Orange Book.
← 47682-0145-13 · Unifirst 47682-0161-13 · Unifirst →
For educational and professional reference only — not medical advice. Pricing reflects published NADAC and CMS ASP (free public data) and may differ from your acquisition cost; always verify before billing or dispensing.