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Amlodipine Besylate 2.5 mg Tablet, 90-count — NDC 72189-689-90 (Billing 72189-0689-90)

by Direct_Rx · 90 TABLET in 1 BOTTLE

This is a package of 90 tablets of Amlodipine Besylate 2.5 mg Tablet from Direct_Rx, marketed since Sep 2026 and currently FDA-listed. It is this product's only package size.

NDC 72189-0689-90
🏷️ FDA NDC (as labeled) 72189-689-90 billing pads the product segment with a zero
Rx only Generic On market Non-controlled ⇄ Compare with another NDC
🗂️ FDA directory synced Oct 1, 2026 · this listing last changed Oct 1, 2026 · sources: openFDA · FDA label (DailyMed) · FDA Orange & Purple Book · First Databank · CMS NADAC, ASP, Medicare & Medicaid · RxNorm
📋 All sources & update times →

This page is curated, coded, and maintained by

Compiled from public FDA, CMS, DailyMed, NADAC, and related drug data sources. Editorial policy

Identity & classification

Regulatory identifiers FDA, NLM and CMS codes for this package

FDA NDC (as labeled) 72189-689-90
Product NDC 72189-689
11-digit billing NDC 72189068990
Application # ANDA203245
SPL Set ID 5c29aadb-b8fd-83c8-e063-6394a90a7a16
Established class (EPC) Calcium Channel Blocker; Dihydropyridine Calcium Channel Blocker
Mechanism of action Calcium Channel Antagonists; Cytochrome P450 3A Inhibitors
Chemical class Dihydropyridines
DEA schedule Non-controlled
Marketing category ANDA
Marketing status On market
FDA listing status Listed (active directory)
Marketing start 2026-09-23
Route ORAL
Dosage form TABLET
Substance AMLODIPINE BESYLATE
TE code (Orange Book) AB · RLD · RS
Why two NDCs? The FDA registers this code as 72189-689-90 — a 5-3-2 layout, and that's what's printed on the package and shown on DailyMed. For insurance claims, every NDC is standardized to a uniform 11-digit 5-4-2 format by adding a zero to the product segment → 72189-0689-90. Same drug, same package — only the format differs.
Where does this data come from?
Identifiers from the FDA openFDA NDC Directory and Structured Product Labeling; RxCUI from RxNorm (NLM); GPI from Medi-Span; GCN / HIC / AHFS / legend from First Databank.

Clinical

📗 Our plain-language guide HelloPharmacist
  • It lowers high blood pressure, which reduces your risk of strokes and heart attacks. It also treats certain kinds of angina (chest pain) and coronary artery disease. Your doctor wi...
  • Take it by mouth, usually once a day, exactly as your prescriber directs. If you use Katerzia suspension, shake it first. It works gradually, so your dose may be adjusted over a we...
  • Ankle or foot swelling is the most common, especially at higher doses. Some people feel tired, dizzy, flushed, or sleepy, or notice a pounding heartbeat. Call your doctor if these...
  • Call if your chest pain worsens, you faint, you notice yellow skin or eyes, or you have swelling of the face or throat. Those need prompt attention.
📖 Read our full Amlodipine guide →
2
Nutrient depletion considerations

Amlodipine Besylate may be associated with lower levels of 2 nutrients — worth a chat with your pharmacist, not a cause for alarm.

🧪 Full Amlodipine Besylate nutrient depletion report →
An association is not a deficiency. Educational only — don't start or stop anything without professional guidance.
Where does this data come from?
Plain-language summary from MedlinePlus (U.S. National Library of Medicine); supplement & herbal interactions and nutrient depletion data from the Natural Medicines database; our full guide is HelloPharmacist editorial content.

Pricing

A drug doesn't have one price. Each row is a different public payment system, and none is what you'd pay at the counter — that depends on your insurance. The ⓘ on each row explains what it measures.

Price systemPer eachPer package
Retail pharmacies payNADAC · weekly Not in the retail survey — common for institutional, discontinued, or low-volume packs.
Medicaid paysCMS SDUD · 12 mo No recent Medicaid claims on file for this NDC — rare and low-volume NDCs are suppressed in the public data.
Medicare drug plans payPart D · quarterly No Part D plan price is available for this NDC in our data.
ℹ️
No price is published for this exact package yet. CMS surveys NADAC per package size, so a different pack of the same drug often has one.
Where does this data come from?
NADAC (National Average Drug Acquisition Cost) is the CMS weekly pharmacy-acquisition-cost survey — what pharmacies pay. ASP (Average Sales Price) is the CMS Medicare Part B drug-payment file, published quarterly. Medicaid pays is computed by us from CMS State Drug Utilization Data (total reimbursed ÷ units, trailing 12 months) — gross of rebates and inclusive of dispensing fees, so it reflects what Medicaid paid, not an acquisition cost. Medicare drug plans pay is the median negotiated point-of-sale unit cost across plans listing this NDC in the CMS quarterly Prescription Drug Plan pricing files, before rebates. The VA pays is the federal contract price (FSS, and the statutory Big 4 ceiling where listed) from the VA National Acquisition Center pharmaceutical price file. All are free public government data; each measures a different payer, so the figures are not directly comparable.

Packaging — all sizes for this product

Package NDCDescription Marketing startMarketing endStatus
72189-0689-90 You're viewing this Main listing 90 TABLET in 1 BOTTLE 2026-09-23 — Active

Therapeutic equivalents

ProductLabelerPackNADAC/unitTEStatusPrice vs. this
Amlodipine Besylate 2.5 mg 29300-0396-05 Unichem 500 tablets $0.011 AB Availability likely —
Amlodipine Besylate 2.5 mg 00904-6369-61 Major 100 tablets $0.011 AB Availability likely —
Amlodipine Besylate 2.5 mg 69097-0126-05 Cipla 90 tablets $0.011 AB Availability likely —
Amlodipine Besylate 2.5 mg 82009-0026-90 Quallent 90 tablets $0.011 AB Discontinued —
amlodipine besylate 2.5 mg 59762-2242-03 Mylan 300 tablets $0.011 AB Availability likely —
Amlodipine Besylate 2.5 mg 67877-0197-05 Ascend 500 tablets $0.011 AB Availability likely —
Amlodipine Besylate 2.5 mg 00480-0083-98 Teva 90 tablets $0.011 AB Discontinued —
Amlodipine Besylate 2.5 mg 67877-0900-05 Ascend 500 tablets $0.011 AB Availability likely —
Amlodipine Besylate 2.5 mg 68180-0233-01 Lupin 90 tablets $0.011 AB Availability likely —
AMLODIPINE BESYLATE 2.5 mg 69584-0021-09 Oxford 90 tablets $0.011 AB Availability likely —
Amlodipine Besylate 2.5 mg 42806-0055-05 Epic 500 tablets $0.016 AB FDA listed —
Amlodipine Besylate 2.5 mg 69097-0836-05 Cipla 90 tablets $0.016 AB FDA listed —
Norvasc 2.5 mg 58151-0353-77 Viatris 90 tablets $8.704 AB Availability likely —
Norvasc 2.5 mg 00069-1520-68 PFIZER 90 tablets $8.704 AB Availability likely —
Amlodipine besylate 2.5 mg 76282-0507-05 Exelan 500 tablets — AB FDA listed —
amlodipine besylate 2.5 mg 52605-0041-10 POLYGEN 1000 tablets — AB Discontinued —
Amlodipine Besylate 2.5 mg 63187-0783-10 Proficient 10 tablets — AB FDA listed —
Amlodipine besylate 2.5 mg 63629-1023-02 Bryant 30 tablets — AB FDA listed —
Amlodipine Besylate 2.5 mg 71610-0732-15 Aphena 15 tablets — AB FDA listed —
Amlodipine besylate 2.5 mg 76282-0237-05 Exelan 500 tablets — AB FDA listed —
AMLODIPINE BESYLATE 2.5 mg 72789-0260-90 PD-Rx 90 tablets — AB FDA listed —
Amlodipine Besylate 2.5 mg 67046-0328-03 Coupler 30 tablets — AB FDA listed —
Amlodipine Besylate 2.5 mg 68788-4082-01 Preferred 100 tablets — AB FDA listed —
Amlodipine Besylate 2.5 mg 70518-1971-00 REMEDYREPACK 30 tablets — AB FDA listed —
Amlodipine besylate 2.5 mg 71335-0833-01 Bryant 30 tablets — AB FDA listed —
AMLODIPINE BESYLATE 2.5 mg 82804-0969-00 Proficient 100 tablets — AB FDA listed —
Amlodipine Besylate 2.5 mg 00615-8647-05 NCS 15 tablets — AB FDA listed —
Amlodipine Besylate 2.5 mg 43489-0102-01 China 90 tablets — AB FDA listed —
Amlodipine Besylate 2.5 mg 72189-0162-90 DIRECT 90 tablets — AB FDA listed —
Amlodipine Besylate 2.5 mg 00615-8429-05 NCS 15 tablets — AB Discontinued —
Amlodipine Besylate 2.5 mg 42291-0025-10 AvKARE 1000 tablets — AB FDA listed —
Amlodipine Besylate 2.5 mg 48433-0155-20 Safecor 100 tablets — AB FDA listed —
Amlodipine Besylate 2.5 mg 50090-1627-00 A-S 60 tablets — AB FDA listed —
Amlodipine Besylate 2.5 mg 50090-7955-01 A-S 90 tablets — AB FDA listed —
Amlodipine Besylate 2.5 mg 55154-8093-00 Cardinal 10 tablets — AB FDA listed —
Amlodipine Besylate 2.5 mg 68382-0121-01 Zydus 100 tablets — AB FDA listed —
Amlodipine Besylate 2.5 mg 71335-0890-01 Bryant 30 tablets — AB FDA listed —
Amlodipine Besylate 2.5 mg 82804-0297-30 Proficient 30 tablets — AB FDA listed —
Amlodipine Besylate 2.5 mg 43063-0764-30 PD-Rx 30 tablets — AB FDA listed —
Amlodipine Besylate 2.5 mg 70518-4629-00 REMEDYREPACK 50 tablets — AB FDA listed —
AMLODIPINE BESYLATE 2.5 mg 71610-0802-60 Aphena 90 tablets — AB FDA listed —
Amlodipine Besylate 2.5 mg 50090-6853-00 A-S 90 tablets — AB FDA listed —
Amlodipine Besylate 2.5 mg 65862-0101-05 Aurobindo 500 tablets — AB FDA listed —
Amlodipine Besylate 2.5 mg 71335-3126-01 Bryant 30 tablets — AB FDA listed —
Amlodipine Besylate 2.5 mg 72789-0514-30 PD-Rx 30 tablets — AB FDA listed —
Amlodipine Besylate 2.5 mg 50090-7956-00 A-S 90 tablets — AB FDA listed —
Amlodipine Besylate 2.5 mg 65841-0620-01 Zydus 100 tablets — AB FDA listed —
Amlodipine Besylate 2.5 mg 68788-8263-01 Preferred 100 tablets — AB FDA listed —
Amlodipine Besylate 2.5 mgthis 72189-0689-90 Direct_Rx 90 tablets — AB FDA listed —
About this product: this is a generic version of the medicine. FDA equivalence ratings are shown when available, and other versions are listed above, least expensive first.
Where does this data come from?
Equivalents are other NDCs of the same ingredient, form and route from the openFDA NDC Directory, ranked least-expensive-first by NADAC. Therapeutic-equivalence (AB) ratings come from the FDA Orange Book; biologics use the FDA Purple Book for biosimilar & interchangeable status.

Availability & generic status

🏛️
2026
On the market since
Sep 2026
📍
2026
Currently FDA-listed
listed with the FDA
🔓
·
Generic on the market
this product is a generic
✅This is a generic drug

This product is an FDA-approved generic. Other versions of the same drug are listed under Therapeutic equivalents, least expensive first.

Where does this data come from?
Patents and exclusivity from the FDA Orange Book (small-molecule drugs), refreshed from public FDA data. Generic launch timing is an estimate, not a guarantee.

Inactive Ingredients / Excipients

Inactive ingredients, also called excipients, are components of the drug product other than the active ingredient. They may include fillers, dyes, coatings, preservatives, flavors, or other formulation ingredients.

Loading inactive ingredients from the official FDA label in the background. No external source is being called by this page request.
Where does this data come from?
Source: official FDA Structured Product Labeling (SPL) via DailyMed and the openFDA label index. Structured IACT rows and label-wide narrative are kept separate; availability and product-level specificity depend on the submitted label.

Inactive ingredient FAQ

Are inactive ingredients the same for every manufacturer?
No. Inactive ingredients can differ by manufacturer, dosage form, strength, and package / product version.
Why might an inactive ingredient be missing?
Some SPLs do not provide a complete structured inactive-ingredient list, and older or unusual labels may only include the information in narrative text.
Can inactive ingredients matter?
Yes. They can matter for allergies, intolerances, dyes, gluten / lactose concerns, preservatives, and formulation differences — but confirm with a pharmacist or the manufacturer when it’s clinically important.

Manufacturer & labeler

LabelerDirect_Rx
Application holderUNICHEM LABORATORIES LTD
FDA applicationANDA203245 (ANDA)
Labeler code72189
First marketedSep 2026
Product typeHuman Prescription Drug
Portfolio355 products on file
The labeler markets the product; the application holder owns the FDA approval. They’re often the same company but can differ (e.g. a repackager or an authorized generic). A mailing address / phone appears here when the manufacturer includes it in the product’s FDA label (not all do).
Where does this data come from?
Labeler, application holder and registered establishment from the FDA openFDA NDC Directory and Drugs@FDA; address/contact from the product’s FDA label.

Full prescribing information FDA SPL

The complete FDA label for this product — the official prescribing information, verbatim, section by section. Jump with a chip, search within the label, or expand everything.
📄 FDA label
📄 FDA label 19 words ▾

No FDA label is on file for this product yet. Labels load from openFDA / DailyMed and refresh weekly.

Source: FDA Structured Product Labeling, mirrored from DailyMed / openFDA. Prefer the government’s original formatting? View this label on DailyMed ↗

Medicare Part D spend CMS · PART D · 2026 (Q1)

Medicare Part D (outpatient prescription) spending for Amlodipine Besylate — the program that covers self-administered drugs. 21 manufacturers.
⚠️ Drug-level data: CMS publishes Part D spending by drug, not by NDC — these figures combine every manufacturer, strength and package size sold under the name Amlodipine Besylate. That’s a different level of aggregation than the Medicaid card above, which is specific to this exact 11-digit NDC (pack size included), so the two aren’t directly comparable.
Period
Total Part D spend
$85.77M
Claims incl. refills
12.9M
Beneficiaries
9.9M
Spend / beneficiary
$8.67
Spend / claim
$6.65
Trend by period
💵 About the dollar figures: spending is what Part D plans paid before confidential manufacturer rebates, so the program’s real net cost is lower. A blank patient count means fewer than 11 people — CMS hides counts that small to protect privacy. Source: CMS Medicare Quarterly Part D Spending by Drug (data.cms.gov), updated quarterly.

About this NDC listing & data coverage

Finished prescription product
What data is (and isn’t) available for this NDC — tap to expand
NDC identity (package / product / labeler codes) ✓ Available
Labeler ✓ Available
Product & package description ✓ Available
Marketing category & status ✓ Available
Active ingredient / dosage form / route ✓ Available
FDA label (SPL via DailyMed) ✓ Available
Package photos — Not published for this NDC No photo available yet for this listing.
Inactive ingredients (structured) — Not published for this NDC The labeler did not submit a structured excipient list, or no SPL is available.
NADAC pharmacy acquisition price (CMS) — Not published for this NDC CMS publishes NADAC only for NDCs reported in its retail-pharmacy survey.
Orange Book / therapeutic-equivalence data ✓ Available
HCPCS J-code billing crosswalk — Not published for this NDC Most self-administered / retail products have no J-code — that is normal.
Medicaid utilization (CMS SDUD) — Not published for this NDC CMS reports utilization only for NDCs with Medicaid claims above its privacy threshold.
“Not published” reflects what the public FDA / CMS / NLM sources provide for this exact package code — it is a property of the data feeds, not a judgment about the product.

Questions about this listing

Why is there no price listed?
The pricing shown on our NDC pages comes from CMS NADAC, a voluntary survey of retail community pharmacy invoices. CMS does not publish a NADAC for every NDC — packages outside the retail survey (institutional and hospital products, bulk packages, discontinued items, and many OTC items) may never receive one. A missing price reflects the survey's scope, not this product's actual cost, and does not mean the product is free or unavailable.
Is the NDC printed on the package the same as the 11-digit billing NDC?
Yes, they identify this exact package in different formats. The form printed on the packaging and shown on DailyMed is the one the FDA registered. Insurance claims use a fixed 11-digit 5-4-2 format, so the short segment is padded with a leading zero and the dashes are dropped. The Identity section at the top of this page lists each form of this code.
Is this package still being marketed?
Yes, per the latest FDA NDC Directory data on this page: this package is listed as actively marketed, with no marketing end date reported by Direct_Rx. Listing status can change — the directory data on this page refreshes weekly.
Who lists this product with the FDA?
Direct_Rx is the labeler of record for this NDC — the company under whose FDA-assigned code the package is listed. The labeler may be the manufacturer itself or a distributor marketing the product under its own code.
Do I need a prescription for this product?
This NDC is listed with FDA as a prescription product, so it is dispensed under a prescriber's order. Your pharmacist can tell you whether any over-the-counter forms of the same medication exist.
This page identifies an FDA-listed package (the NDC) and reports public regulatory and pricing data about the listing. It is reference information, not a medical recommendation — talk to your pharmacist or prescriber about your own medication.
Where does this data come from?
Listing facts (marketing category, packager status, marketing dates) from the FDA openFDA NDC Directory; label availability from DailyMed; pricing coverage from CMS NADAC; equivalence scope from the FDA Orange Book.
← 72189-0688-35 · Direct_Rx 72189-0690-90 · Direct_Rx →
For educational and professional reference only — not medical advice. Pricing reflects published NADAC and CMS ASP (free public data) and may differ from your acquisition cost; always verify before billing or dispensing.