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J0132

J0132 – Injection, acetylcysteine, 100 mg · NDC Crosswalk & Billing Units

HCPCS Level II J-code · Medicare Part B drug billing
J-code ● 13 NDCs crosswalked per 100 MG $0.389/unit ASP+6%

📋 J0132 summary

J0132 is a HCPCS Level II J-code used to bill acetylcysteine, 100 mg, billed per 100 MG. The number of billing units to report depends on the dose administered and the NDC/package billed — use the calculator below.

Brand names associated with J0132: Acetadote*, Acetylcysteine, Acetadote

Code J0132 Billing unit 100 MG Payment limit $0.389/unit NDC-Crosswalk 13 Quarter Q3 2026 RxCUI Atlas Trace the drug concept →

⚠ An NDC↔HCPCS crosswalk and a published payment limit do not guarantee payer coverage or payment. Always verify the current payer policy and claim format before billing.

🗂️ Key billing facts

HCPCS codeJ0132
DescriptorInjection, acetylcysteine, 100 mg
Billing unit100 MG
Payment limit / unit$0.389
Est. ASP / unit$0.367 est.
Mapped NDCs13
Data periodQ3 2026
Last updated2026-08-20

💊 About Acetylcysteine DRUG GUIDE

Acetylcysteine has two main uses.

As an antidote, it is used to prevent or reduce liver injury after a potentially dangerous acetaminophen (Tylenol) overdose — given either intravenously (by IV) or orally.

Acetadote and Acetylcysteine injections are specifically approved for this use in adults and children weighing 5 kg or more, including both acute (single large) overdoses and repeated higher-than-recommended doses.The inhalation solution and inhaler forms of Acetylcysteine are used as add-on therapy to help loosen and thin thick, sticky mucus in the airways.

This includes conditions such as chronic emphysema, chronic asthmatic bronchitis, tuberculosis, bronchiectasis, cystic fibrosis, pneumonia, tracheobronchitis, and situations like post-surgery pulmonary complications or tracheostomy care.

Read the full Acetylcysteine drug guide →
Clinical overview from our editorial drug guide for Acetylcysteine. For billing reference, see the sections above.

🧾 Billing & reimbursement HCPCS · CMS · EFF. Q3 2026

📅 Payment limits effective Q3 2026 — from the CMS Medicare Part B Payment Limit File (revised quarterly).
Medicare payment limit / unit
$0.389
Est. ASP / unit
$0.367 est.
Est. after 2% sequester
$0.381
HCPCS dosage
100 MG
The CMS payment limit is the Medicare Part B drug allowance (ASP + 6%, statutory). After the 2% federal sequester the effective payment is ≈ ASP + 4.3%; estimated ASP = payment limit ÷ 1.06. Source: CMS Medicare Part B Payment Limit File (quarterly), Q3 2026.
Full HCPCS code details (official CMS record)
Long descriptionInjection, acetylcysteine, 100 mg
CoverageC — Carrier/MAC judgment
Pricing indicator51 — Drug — priced under the ASP methodology
Type of service1 — Medical care
BETOS-2O1E
ASC payment group
Action codeN — No maintenance this year
Effective date2018-01-01
Date added2006-01-01
Source: CMS HCPCS Level II code file (imported via admin).

🧮 Dosing & billing-units calculator HCPCS UNITS

One billing unit of J0132 = 100 mg. Enter a regimen to convert dose → billing units and project a full course.
Billing units = dose ÷ HCPCS unit size. Most payers require whole units — round per the payer's policy. “Est. Medicare pay” uses the current payment limit. For single-dose vials, drug discarded after administration may be separately billable with modifier JW (JZ when none is discarded) where allowed. Always verify payer-specific rounding before billing.

🔁 NDCs that bill under J0132 WITH EST. MEDICARE PAY

13 NDCs map to J0132. Bill units = how many HCPCS units one package represents. Est. pay / pkg = payment limit ($0.389/unit) × that package's bill units.
NDC (11-digit)DrugLabelerPackageStrength Bill units Est. pay / pkg NADAC / unit StatusSource
00574-0805-30 acetylcysteine 200 mg/mL INJECTION Padagis 4 VIAL in 1 CARTON (0574-0805-30) / 30 mL... 200 mg/mL 240 $93.36 ● Active CMS + PDAC
25021-0812-30 Acetylcysteine 200 mg/mL INJECTION, SOLUTION Sagent 4 VIAL in 1 CARTON (25021-812-30) / 30 mL... 200 mg/mL 240 $93.36 ● Active CMS + PDAC
25021-0812-66 Acetylcysteine 200 mg/mL INJECTION, SOLUTION Sagent 4 VIAL in 1 CARTON (25021-812-66) / 30 mL... 200 mg/mL 240 $93.36 ● Active CMS + PDAC
55150-0259-30 Acetylcysteine 6 g/30mL INJECTION, SOLUTION Eugia 4 VIAL, SINGLE-DOSE in 1 CARTON (55150-259... 6 g/30mL 240 $93.36 ● Active CMS + PDAC
63323-0963-30 Acetylcysteine 200 mg/mL INJECTION, SOLUTION Fresenius 4 VIAL, SINGLE-DOSE in 1 CARTON (63323-963... 200 mg/mL 240 $93.36 ● Active CMS ASP
63323-0963-44 Acetylcysteine 200 mg/mL INJECTION, SOLUTION Fresenius 4 VIAL, SINGLE-DOSE in 1 CARTON (63323-963... 200 mg/mL 240 $93.36 ● Active CMS + PDAC
66220-0207-30 ACETADOTE Acetylcysteine 200 mg/mL INJECTION, SOLUTION Cumberland 4 VIAL in 1 CARTON (66220-207-30) / 30 mL... 200 mg/mL 240 $93.36 ● Active CMS ASP
68462-0946-12 Acetylcysteine 200 mg/mL INJECTION, SOLUTION Glenmark 4 VIAL, SINGLE-DOSE in 1 CARTON (68462-946... 200 mg/mL 240 $93.36 ● Active CMS + PDAC
70069-0788-04 Acetylcysteine 200 mg/mL INJECTION, SOLUTION Somerset 4 VIAL in 1 CARTON (70069-788-04) / 30 mL... 200 mg/mL 240 $93.36 ● Active CMS + PDAC
70594-0111-02 Acetylcysteine 200 mg/mL INJECTION, SOLUTION Xellia 4 VIAL in 1 CARTON (70594-111-02) / 30 mL... 200 mg/mL 240 $93.36 ● Active CMS + PDAC
00143-9433-04 Acetylcysteine 200 mg/mL INJECTION, SOLUTION Hikma 4 VIAL in 1 CARTON (0143-9433-04) / 30 mL... 200 mg/mL 2 $0.78 ● Active PDAC
72611-0860-04 ACETYLCYSTEINE (SDV,PF,LATEX-FREE) 200 MG/1 ML Unknown 2 $0.78 PDAC
17478-0660-30 ACETYLCYSTEINE (SDV; 4X30ML,PF) 200 MG/ML Unknown 2 $0.78 PDAC
NDC→HCPCS mappings come from the CMS ASP NDC-HCPCS crosswalk; additional DME MAC / DMEPOS mappings come from PDAC and are labeled separately. NADAC from CMS (weekly). “Status” reflects the product's marketing / obsolete flag in the NDC directory. Presence or absence here does not determine Medicare coverage. Linked NDCs open the full product page.

📊 Medicare utilization & spend CMS · PART B · 2026 (Q1)

Period
Total Part B spend
$8.67
Claims
21
Beneficiaries
Spend / beneficiary
Spend / claim
$0.41
Trend by period
Where J0132 ranks among Part B drugs · 2026 (Q1) · neighbors ±5

Full breakdown by period (2)
PeriodTotal spendBeneficiariesClaims$/beneficiary$/claim
2026 (Q1) $8.67 21 $0.41
2025 (Q1-Q4) $395.24 131 471 $3.02 $0.84
Provider-administered (Part B) spend, calculated for the whole HCPCS code (CMS does not publish Medicare spend per individual NDC). Self-administered use is covered under Part D instead. A blank patient count means fewer than 11 people — CMS hides counts that small to protect privacy. Source: CMS Medicare Quarterly Part B Spending by Drug (data.cms.gov), updated quarterly.

📈 Medicare Part B claims detail CMS PSPS · 2024

Calendar-year 2024 Medicare Part B fee-for-service activity for this HCPCS code, summed across all carriers, localities and specialties (CMS Physician/Supplier Procedure Summary). A “service” is one billed line/unit — not one claim — so counts run higher than claim counts.
Allowed charges
$270.87
Medicare paid
$206.74
Submitted services
2,267
Denial rate
76.3%
Allowed / service
$0.50
Submitted charges
$32.1K
Source: CMS Physician/Supplier Procedure Summary (PSPS), CY2024 — Medicare Part B carrier + DME fee-for-service claims (excludes Medicare Advantage). Figures are for the whole HCPCS code, which may cover uses beyond this drug. ⚠ CMS hides any figure covering fewer than 11 patients (a privacy rule), so totals — especially denials and low-volume codes — run a little low.

🗺️ Where J0132 is utilized CMS · BY PROVIDER · 2024

Medicare Part B services for this code by the rendering provider's state — 1,071 services across 2 states & territories in 2024 (CMS reports include DC and U.S. territories). Switch to per 100k to compare states fairly regardless of population. Hover or tap a state for its top ZIP codes.
Hover or tap a state to see its numbers + top ZIP codes.
Per-capita = services ÷ 2023 state population × 100,000 (so high-population states aren't automatically "hotter"). Counts reflect the provider's location, not the patient's. Providers with fewer than 11 patients are hidden by CMS for privacy, so totals run low and per-100k can be noisy in small states — read this as relative geography, not exact counts. Source: CMS Medicare Physician & Other Practitioners — by Provider and Service, 2024.

📊 What bills under J0132

J-codes are billing codes often used for drugs billed under the medical benefit. This connects the billing code to the NDC package records it covers, by ingredient and labeler.

NDC products by ingredient
Acetylcysteine 8
acetylcysteine 2
NDC products by labeler
Sagent Pharmaceuticals 2
Fresenius Kabi USA, LLC 2
Hikma Pharmaceuticals USA Inc. 1
Padagis US LLC 1
Eugia US LLC 1
Glenmark Pharmaceuticals Inc., USA 1
Somerset Therapeutics, LLC 1
Xellia Pharmaceuticals USA LLC 1

🗃️ Data sources & freshness

Every figure on this page is computed from public datasets. Here's what each section draws on and how current it is.
HCPCS code & descriptor
CMS HCPCS Level II code file
Loaded
Payment limit & billing unit
CMS Medicare Part B ASP Pricing File (quarterly)
Q3 2026 · as of 2026-08-20
NDC ↔ HCPCS crosswalk
CMS ASP NDC-HCPCS crosswalk + DMEPDAC (PDAC)
13 NDCs mapped
NADAC acquisition cost
CMS National Average Drug Acquisition Cost (weekly)
Not available for mapped NDCs
Utilization & spend
CMS Part B Spending by Drug · PSPS · Physician & Other Practitioners
Latest data year 2026
Figures are estimates for reference and may lag the source files. Always verify against the current CMS files and your payer's policy before submitting claims.

⚠️ Practical billing caveats

  • A crosswalk is not coverage. An NDC mapping or a published payment limit does not guarantee a payer will cover or pay this code. Check the specific plan's policy.
  • Units ≠ milligrams. Bill the number of HCPCS units (dose ÷ the code's unit size), not the milligram dose. Use the calculator above.
  • Discarded drug. For single-dose vials, drug discarded after administration may be separately billable with modifier JW (and JZ when nothing is discarded) where the payer allows.
  • Rounding & partial units. Many payers require whole units; round per the payer's policy, not automatically up.
  • The code can cover more than this drug. Some HCPCS codes span multiple products or strengths — confirm the exact code for the product administered.
  • Figures lag. ASP limits change quarterly and utilization data are released with a delay. Verify against the current CMS files before billing.

J0132 billing FAQ

What is HCPCS code J0132?
J0132 is a HCPCS Level II J-code used to bill Injection, acetylcysteine, 100 mg under Medicare Part B and most medical (not pharmacy) benefits.
What is the billing unit for J0132?
One unit of J0132 represents 100 MG. Report the number of units equal to the dose administered divided by 100 MG.
How many units of J0132 should I bill?
Divide the dose administered by the code's unit size (100 MG) to get the number of billing units, then round per your payer's policy. The calculator on this page converts a dose into billing units and projects a full course.
How much does Medicare pay for J0132?
The Medicare Part B payment limit is $0.389 per unit (Q3 2026), based on ASP + 6%. After the 2% sequester the effective payment is about $0.381 per unit. Payment limits are revised quarterly.
Which NDCs bill under J0132?
13 NDCs currently map to J0132 in the CMS ASP NDC-HCPCS crosswalk. See the NDC crosswalk table above for each product, package, billing units and estimated reimbursement.
Does a crosswalk mean J0132 is covered?
No. An NDC-to-HCPCS crosswalk and a published payment limit do not guarantee coverage or payment. Coverage depends on the payer, the diagnosis and the site of care — always verify the current policy before billing.
For professional billing reference only — verify against the current CMS files before submitting claims.