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J2312

J2312 – Inj naloxone hcl nos, 0.01mg · NDC Crosswalk & Billing Units

HCPCS Level II J-code · Medicare Part B drug billing
J-code ● 47 NDCs crosswalked per 0.01 MG $0.069/unit ASP+6%

This page is curated, coded, and maintained by

Compiled from public FDA, CMS, DailyMed, NADAC, and related drug data sources. Editorial policy

📋 J2312 summary

J2312 is a HCPCS Level II J-code used to bill naloxone hcl nos, 0.01mg, billed per 0.01 MG. The number of billing units to report depends on the dose administered and the NDC/package billed — use the calculator below.

Brand names associated with J2312: Naloxone Hcl(J2312), Naloxone Hydrochloride, Naloxone Hci

Code J2312 Billing unit 0.01 MG Payment limit $0.069/unit NDC-Crosswalk 47 Quarter Q3 2026 RxCUI Atlas Trace the drug concept →

⚠ An NDC↔HCPCS crosswalk and a published payment limit do not guarantee payer coverage or payment. Always verify the current payer policy and claim format before billing.

🗂️ Key billing facts

HCPCS codeJ2312
DescriptorInj naloxone hcl nos, 0.01mg
Billing unit0.01 MG
Payment limit / unit$0.069
Est. ASP / unit$0.065 est.
Mapped NDCs47
Data periodQ3 2026
Last updated2026-08-20

🧾 Billing & reimbursement HCPCS · CMS · EFF. Q3 2026

📅 Payment limits effective Q3 2026 — from the CMS Medicare Part B Payment Limit File (revised quarterly).
Medicare payment limit / unit
$0.069
Est. ASP / unit
$0.065 est.
Est. after 2% sequester
$0.068
HCPCS dosage
0.01 MG
The CMS payment limit is the Medicare Part B drug allowance (ASP + 6%, statutory). After the 2% federal sequester the effective payment is ≈ ASP + 4.3%; estimated ASP = payment limit ÷ 1.06. Source: CMS Medicare Part B Payment Limit File (quarterly), Q3 2026.

🧮 Dosing & billing-units calculator HCPCS UNITS

One billing unit of J2312 = 0.01 mg. Enter a regimen to convert dose → billing units and project a full course.
Billing units = dose ÷ HCPCS unit size. Most payers require whole units — round per the payer's policy. “Est. Medicare pay” uses the current payment limit. For single-dose vials, drug discarded after administration may be separately billable with modifier JW (JZ when none is discarded) where allowed. Always verify payer-specific rounding before billing.

🔁 NDCs that bill under J2312 LEAST EXPENSIVE FIRST

47 NDCs map to J2312. Bill units = how many HCPCS units one package represents. Est. pay / pkg = payment limit ($0.069/unit) × that package's bill units.
NDC (11-digit)DrugLabelerPackageStrength Bill units Est. pay / pkg NADAC / unit StatusSource
00409-1215-01 Naloxone Hydrochloride .4 mg/mL INJECTION, SOLUTION Hospira, 10 VIAL, SINGLE-DOSE in 1 CARTON (0409-121... .4 mg/mL 400 $27.60 $4.015 ● Active CMS + PDAC
36000-0308-10 naloxone hydrochloride .4 mg/mL INJECTION, SOLUTION Baxter 10 VIAL, SINGLE-DOSE in 1 CARTON (36000-30... .4 mg/mL 400 $27.60 $4.015 ● Active CMS + PDAC
36000-0310-02 NALOXONE HYDROCHLORIDE .4 mg/mL INJECTION, SOLUTION Baxter 1 VIAL, MULTI-DOSE in 1 CARTON (36000-310-... .4 mg/mL 400 $27.60 $4.015 ● Active CMS + PDAC
67457-0292-02 Naloxone Hydrochloride .4 mg/mL INJECTION, SOLUTION Mylan 10 VIAL, SINGLE-DOSE in 1 CARTON (67457-29... .4 mg/mL 400 $27.60 $4.015 Obsolete CMS ASP
70069-0071-10 Naloxone Hydrochloride .4 mg/mL INJECTION, SOLUTION Somerset 10 VIAL in 1 CARTON (70069-071-10) / 1 mL... .4 mg/mL 400 $27.60 $4.015 ● Active CMS + PDAC
70756-0658-10 naloxone hydrochloride .4 mg/mL INJECTION, SOLUTION Lifestar 10 VIAL, SINGLE-DOSE in 1 CARTON (70756-65... .4 mg/mL 400 $27.60 $4.015 ● Active CMS + PDAC
72603-0590-10 naloxone hydrochloride .4 mg/mL INJECTION, SOLUTION NorthStar 10 VIAL, SINGLE-DOSE in 1 CARTON (72603-59... .4 mg/mL 400 $27.60 $4.015 ● Active CMS + PDAC
42023-0224-01 Naloxone Hydrochloride 1 mg/mL INJECTION Par 1 SYRINGE, GLASS in 1 CARTON (42023-224-01... 1 mg/mL 200 $13.80 $6.284 ● Active CMS + PDAC
67457-0992-02 Naloxone Hydrochloride 1 mg/mL INJECTION, SOLUTION Mylan 1 SYRINGE, GLASS in 1 CARTON (67457-992-02... 1 mg/mL 400 $27.60 $6.284 ● Active CMS + PDAC
55150-0327-10 Naloxone Hydrochloride .4 mg/mL INJECTION, SOLUTION Eugia 10 VIAL, SINGLE-DOSE in 1 CARTON (55150-32... .4 mg/mL 40 $2.76 $6.488 ● Active PDAC
00641-6205-10 Naloxone Hydrochloride 1 mg/mL INJECTION Hikma 10 SYRINGE in 1 CARTON (0641-6205-10) / 2... 1 mg/mL 4,000 $276.00 $13.505 ● Active CMS + PDAC
43066-0142-10 naloxone hydrochloride 1 mg/mL INJECTION, SOLUTION Baxter 10 CARTON in 1 CARTON (43066-142-10) / 1... 1 mg/mL 2,000 $138.00 $13.505 ● Active CMS + PDAC
43598-0750-10 Naloxone Hydrochloride 1 mg/mL INJECTION Dr. 10 SYRINGE in 1 BOX (43598-750-10) / 2 mL... 1 mg/mL 2,000 $138.00 $13.505 ● Active CMS + PDAC
55150-0345-10 Naloxone Hydrochloride 1 mg/mL INJECTION, SOLUTION Eugia 10 SYRINGE in 1 BOX (55150-345-10) / 2 mL... 1 mg/mL 2,000 $138.00 $13.505 ● Active CMS + PDAC
00404-9773-01 NALOXONE HYDROCHLORIDE .4 mg/mL INJECTION, SOLUTION Henry 1 VIAL, SINGLE-DOSE in 1 BAG (0404-9773-01... .4 mg/mL 40 $2.76 — ● Active CMS ASP
00404-9920-01 Naloxone Hydrochloride .4 mg/mL INJECTION, SOLUTION Henry 1 BOX in 1 BAG (0404-9920-01) / 1 CARTRID... .4 mg/mL 40 $2.76 — ● Active CMS ASP
00404-9921-02 Naloxone HCl Henry — — 200 $13.80 — — CMS ASP
00404-9922-02 NALOXONE HYDROCHLORIDE 1 mg/mL INJECTION Henry 1 SYRINGE in 1 BAG (0404-9922-02) / 2 mL... 1 mg/mL 200 $13.80 — ● Active CMS ASP
00404-9923-01 NALOXONE HYDROCHLORIDE .4 mg/mL INJECTION, SOLUTION Henry 1 VIAL, SINGLE-DOSE in 1 BAG (0404-9923-01... .4 mg/mL 40 $2.76 — Obsolete CMS ASP
00409-1219-01 Naloxone Hydrochloride .4 mg/mL INJECTION, SOLUTION Hospira, 25 CARTON in 1 CASE (0409-1219-01) / 1 VI... .4 mg/mL 10,000 $690.00 — ● Active CMS + PDAC
00409-1782-69 Naloxone Hydrochloride .4 mg/mL INJECTION, SOLUTION Hospira, 10 CARTRIDGE in 1 BOX (0409-1782-69) / 1... .4 mg/mL 400 $27.60 — ● Active CMS + PDAC
00641-6132-25 Naloxone Hydrochloride Nalxone .4 mg/mL INJECTION Hikma 25 VIAL in 1 CARTON (0641-6132-25) / 1 mL... .4 mg/mL 1,000 $69.00 — ● Active CMS + PDAC
00641-6193-10 Naloxone Hydrochloride .4 mg/mL INJECTION Hikma 10 SYRINGE in 1 CARTON (0641-6193-10) / 1... .4 mg/mL 400 $27.60 — ● Active CMS + PDAC
43598-0750-58 Naloxone HCl Dr. — — 2,000 $138.00 — — CMS ASP
50090-3294-00 Naloxone HCl A-S — — 400 $27.60 — — CMS ASP
50090-5427-00 Naloxone Hydrochloride .4 mg/mL INJECTION, SOLUTION A-S 10 VIAL in 1 CARTON (50090-5427-0) / 1 mL... .4 mg/mL 400 $27.60 — ● Active CMS ASP
50090-6491-00 Naloxone Hydrochloride .4 mg/mL INJECTION, SOLUTION A-S 10 VIAL, SINGLE-DOSE in 1 CARTON (50090-64... .4 mg/mL 400 $27.60 — ● Active CMS ASP
51662-1238-01 NALOXONE HYDROCHLORIDE .4 mg/mL INJECTION, SOLUTION HF 1 mL in 1 CARTRIDGE (51662-1238-1) .4 mg/mL 40 $2.76 — ● Active CMS ASP
51662-1239-01 NALOXONE HYDROCHLORIDE 1 mg/mL INJECTION HF 1 SYRINGE, PLASTIC in 1 BOX (51662-1239-1)... 1 mg/mL 200 $13.80 — ● Active CMS ASP
51662-1239-03 NALOXONE HYDROCHLORIDE 1 mg/mL INJECTION HF 10 POUCH in 1 CASE (51662-1239-3) / 1 mL... 1 mg/mL 2,000 $138.00 — ● Active CMS ASP
51662-1242-01 NALOXONE HCI .4 mg/mL INJECTION, SOLUTION HF 1 mL in 1 VIAL (51662-1242-1) .4 mg/mL 40 $2.76 — ● Active CMS ASP
51662-1242-03 NALOXONE HCI .4 mg/mL INJECTION, SOLUTION HF 50 POUCH in 1 CASE (51662-1242-3) / 1 mL... .4 mg/mL 2,000 $138.00 — ● Active CMS ASP
51662-1385-01 NALOXONE HYDROCHLORIDE .4 mg/mL INJECTION, SOLUTION HF 1 VIAL, MULTI-DOSE in 1 CARTON (51662-1385... .4 mg/mL 400 $27.60 — ● Active CMS ASP
51662-1586-01 NALOXONE HYDROCHLORIDE 1 mg/mL INJECTION, SOLUTION HF 1 SYRINGE in 1 BOX (51662-1586-1) / 2 mL... 1 mg/mL 200 $13.80 — ● Active CMS ASP
51662-1586-03 NALOXONE HYDROCHLORIDE 1 mg/mL INJECTION, SOLUTION HF 10 POUCH in 1 CASE (51662-1586-3) / 1 BOX... 1 mg/mL 2,000 $138.00 — ● Active CMS ASP
55150-0328-10 NALOXONE HYDROCHLORIDE .4 mg/mL INJECTION, SOLUTION Eugia 10 VIAL, MULTI-DOSE in 1 CARTON (55150-328... .4 mg/mL 4,000 $276.00 — ● Active CMS + PDAC
67457-0299-10 Naloxone Hydrochloride .4 mg/mL INJECTION, SOLUTION Mylan 10 VIAL, MULTI-DOSE in 1 CARTON (67457-299... .4 mg/mL 4,000 $276.00 — ● Active CMS + PDAC
67457-0599-02 Naloxone HCl Mylan — — 400 $27.60 — — CMS ASP
67457-0645-02 Naloxone HCl Mylan — — 400 $27.60 — — CMS + PDAC
67457-0987-10 Naloxone HCl Mylan — — 4,000 $276.00 — — CMS + PDAC
70069-0072-10 Naloxone Hydrochloride .4 mg/mL INJECTION, SOLUTION Somerset 10 CARTON in 1 BOX (70069-072-10) / 1 VIA... .4 mg/mL 4,000 $276.00 — ● Active CMS + PDAC
70756-0658-25 naloxone hydrochloride .4 mg/mL INJECTION, SOLUTION Lifestar 25 VIAL, SINGLE-DOSE in 1 CARTON (70756-65... .4 mg/mL 1,000 $69.00 — ● Active CMS + PDAC
72572-0450-25 Naloxone Hydrochloride Nalxone .4 mg/mL INJECTION Civica, 25 VIAL in 1 CARTON (72572-450-25) / 1 mL... .4 mg/mL 1,000 $69.00 — ● Active CMS + PDAC
72603-0590-25 naloxone hydrochloride .4 mg/mL INJECTION, SOLUTION NorthStar 25 VIAL, SINGLE-DOSE in 1 CARTON (72603-59... .4 mg/mL 1,000 $69.00 — ● Active CMS + PDAC
76045-0112-20 Naloxone Hydrochloride 1 mg/mL INJECTION, SOLUTION Fresenius 24 SYRINGE in 1 CASE (76045-112-20) / 2 m... 1 mg/mL 4,800 $331.20 — ● Active CMS + PDAC
76045-0114-10 Naloxone Hydrochloride .4 mg/mL INJECTION, SOLUTION Fresenius 24 SYRINGE in 1 CARTON (76045-114-10) / 1... .4 mg/mL 960 $66.24 — ● Active CMS + PDAC
71288-0814-81 Naloxone HCl 10X1ML;SINGLE DOSE 0.4 MG/1 ML Unknown — — 40 $2.76 — — PDAC
NDC→HCPCS mappings come from the CMS ASP NDC-HCPCS crosswalk; additional DME MAC / DMEPOS mappings come from PDAC and are labeled separately. NADAC from CMS (weekly). “Status” reflects the product's marketing / obsolete flag in the NDC directory. Presence or absence here does not determine Medicare coverage. Linked NDCs open the full product page.

📊 Medicare utilization & spend CMS · PART B · 2026 (Q1)

Period
Total Part B spend
$175.36
Claims
18
Beneficiaries
18
Spend / beneficiary
$9.74
Spend / claim
$9.74
Trend by period
Where J2312 ranks among Part B drugs · 2026 (Q1) · neighbors ±5
Total spending — #805 of 824
#800 BENTYL* J0500 $265.01 #801 CONRAY Q9961 $251.21 #802 GLYCOPYRROLATE(J1596... J1596 $240.57 #803 COMBOGESIC IV J0138 $209.95 #804 MORPHINE SULFATE(J22... J2272 $209.58 #805 NALOXONE HCL(J2312) J2312 $175.36 #806 DILTIAZEM HCL-0.9% N... J1163 $166.44 #807 ADRENALIN(J0165)* J0165 $164.81 #808 PROGESTERONE J2675 $144.09 #809 LIDOCAINE HCL IN 5%... J2002 $140.95 #810 EPINEPHRINE J0166 $125.51
Total claims — #794 of 824
#789 DUAL LAYER IMPAX, PE... Q4262 20 #790 BENZTROPINE MESYLATE J0515 19 #791 STELARA(J3357)* J3357 19 #792 CORIFACT J7180 19 #793 DERMA-GIDE, 1 SQ CM*... Q4203 19 #794 NALOXONE HCL(J2312) J2312 18 #795 DOXERCALCIFEROL* J1270 17 #796 ZALTRAP J9400 17 #797 MLG COMPLET, PER SQ... Q4256 17 #798 METHADONE HCL J1230 16 #799 NOVOEIGHT J7182 16

Full breakdown by period (2)
PeriodTotal spendBeneficiariesClaims$/beneficiary$/claim
2026 (Q1) $175.36 18 18 $9.74 $9.74
2025 (Q1-Q4) $139.40 23 23 $6.06 $6.06
Provider-administered (Part B) spend, calculated for the whole HCPCS code (CMS does not publish Medicare spend per individual NDC). Self-administered use is covered under Part D instead. A blank patient count means fewer than 11 people — CMS hides counts that small to protect privacy. Source: CMS Medicare Quarterly Part B Spending by Drug (data.cms.gov), updated quarterly.

📈 Medicare Part B claims detail CMS PSPS · 2024

Calendar-year 2024 Medicare Part B fee-for-service activity for this HCPCS code, summed across all carriers, localities and specialties (CMS Physician/Supplier Procedure Summary). A “service” is one billed line/unit — not one claim — so counts run higher than claim counts.
Allowed charges
$47.64
Medicare paid
$38.14
Submitted services
933
Denial rate
27.1%
Allowed / service
$0.07
Submitted charges
$927.83
Source: CMS Physician/Supplier Procedure Summary (PSPS), CY2024 — Medicare Part B carrier + DME fee-for-service claims (excludes Medicare Advantage). Figures are for the whole HCPCS code, which may cover uses beyond this drug. ⚠ CMS hides any figure covering fewer than 11 patients (a privacy rule), so totals — especially denials and low-volume codes — run a little low.

📊 What bills under J2312

J-codes are billing codes often used for drugs billed under the medical benefit. This connects the billing code to the NDC package records it covers, by ingredient and labeler.

NDC products by ingredient
Naloxone Hydrochloride 10
NALOXONE HYDROCHLORIDE 7
naloxone hydrochloride 5
Nalxone Hydrochloride 3
NDC products by labeler
Hospira, Inc. 3
Hikma Pharmaceuticals USA Inc. 3
Baxter Healthcare Corporation 3
Eugia US LLC 3
Dr. Reddy's Laboratories, Inc. 2
Mylan Institutional LLC 2
Somerset Therapeutics, LLC 2
Civica, Inc. 2

🗃️ Data sources & freshness

Every figure on this page is computed from public datasets. Here's what each section draws on and how current it is.
HCPCS code & descriptor
CMS HCPCS Level II code file
Not available in current dataset
Payment limit & billing unit
CMS Medicare Part B ASP Pricing File (quarterly)
Q3 2026 · as of 2026-08-20
NDC ↔ HCPCS crosswalk
CMS ASP NDC-HCPCS crosswalk + DMEPDAC (PDAC)
47 NDCs mapped
NADAC acquisition cost
CMS National Average Drug Acquisition Cost (weekly)
Available for mapped NDCs
Utilization & spend
CMS Part B Spending by Drug · PSPS · Physician & Other Practitioners
Latest data year 2026
Figures are estimates for reference and may lag the source files. Always verify against the current CMS files and your payer's policy before submitting claims.

⚠️ Practical billing caveats

  • A crosswalk is not coverage. An NDC mapping or a published payment limit does not guarantee a payer will cover or pay this code. Check the specific plan's policy.
  • Units ≠ milligrams. Bill the number of HCPCS units (dose ÷ the code's unit size), not the milligram dose. Use the calculator above.
  • Discarded drug. For single-dose vials, drug discarded after administration may be separately billable with modifier JW (and JZ when nothing is discarded) where the payer allows.
  • Rounding & partial units. Many payers require whole units; round per the payer's policy, not automatically up.
  • The code can cover more than this drug. Some HCPCS codes span multiple products or strengths — confirm the exact code for the product administered.
  • Figures lag. ASP limits change quarterly and utilization data are released with a delay. Verify against the current CMS files before billing.

❓ J2312 billing FAQ

What is HCPCS code J2312?
J2312 is a HCPCS Level II J-code used to bill Inj naloxone hcl nos, 0.01mg under Medicare Part B and most medical (not pharmacy) benefits.
What is the billing unit for J2312?
One unit of J2312 represents 0.01 MG. Report the number of units equal to the dose administered divided by 0.01 MG.
How many units of J2312 should I bill?
Divide the dose administered by the code's unit size (0.01 MG) to get the number of billing units, then round per your payer's policy. The calculator on this page converts a dose into billing units and projects a full course.
How much does Medicare pay for J2312?
The Medicare Part B payment limit is $0.069 per unit (Q3 2026), based on ASP + 6%. After the 2% sequester the effective payment is about $0.068 per unit. Payment limits are revised quarterly.
Which NDCs bill under J2312?
47 NDCs currently map to J2312 in the CMS ASP NDC-HCPCS crosswalk. See the NDC crosswalk table above for each product, package, billing units and estimated reimbursement.
Does a crosswalk mean J2312 is covered?
No. An NDC-to-HCPCS crosswalk and a published payment limit do not guarantee coverage or payment. Coverage depends on the payer, the diagnosis and the site of care — always verify the current policy before billing.
For professional billing reference only — verify against the current CMS files before submitting claims.