J2675
J2675 – Injection, progesterone, per 50 mg · NDC Crosswalk & Billing Units
HCPCS Level II J-code · Medicare Part B drug billing
J-code
● 45 NDCs crosswalked per 50 MG $0.559/unit ASP+6%
📋 J2675 summary
J2675 is a HCPCS Level II J-code used to bill progesterone, per 50 mg, billed per 50 MG. The number of billing units to report depends on the dose administered and the NDC/package billed — use the calculator below.
Code J2675
Billing unit 50 MG Payment limit $0.559/unit NDC-Crosswalk 45
Quarter Q3 2026
RxCUI Atlas Trace the drug concept →
⚠ An NDC↔HCPCS crosswalk and a published payment limit do not guarantee payer coverage or payment. Always verify the current payer policy and claim format before billing.
🗂️ Key billing facts
HCPCS codeJ2675
DescriptorInjection, progesterone, per 50 mg
Billing unit50 MG
Payment limit / unit$0.559
Est. ASP / unit$0.527 est.
Mapped NDCs45
Data periodQ3 2026
Last updated2026-08-20
💊 About Progesterone DRUG GUIDE
Progesterone capsules (including Prometrium) are used to prevent endometrial hyperplasia (abnormal thickening of the uterine lining) in postmenopausal women with a uterus who are taking estrogen, and to treat secondary amenorrhea (missed periods not caused by pregnancy).Progesterone injection is indicated for amenorrhea and abnormal uterine bleeding caused by a hormonal imbalance.
Crinone vaginal gel is used as part of Assisted Reproductive Technology (ART) for progesterone supplementation or replacement, and Crinone 4% is also indicated for secondary amenorrhea.
Vaginal inserts — including Endometrin and other progesterone vaginal insert products — are used to support embryo implantation and early pregnancy as part of an ART treatment program for infertile women.
Clinical overview from our editorial drug guide for Progesterone. For billing reference, see the sections above.
🧾 Billing & reimbursement HCPCS · CMS · EFF. Q3 2026
📅 Payment limits effective Q3 2026 — from the CMS Medicare Part B Payment Limit File (revised quarterly).
Medicare payment limit / unit
$0.559
Est. ASP / unit
$0.527 est.
Est. after 2% sequester
$0.548
HCPCS dosage
50 MG
The CMS payment limit is the Medicare Part B drug allowance (ASP + 6%, statutory). After the 2% federal sequester the effective payment is ≈ ASP + 4.3%; estimated ASP = payment limit ÷ 1.06. Source: CMS Medicare Part B Payment Limit File (quarterly), Q3 2026.
Full HCPCS code details (official CMS record)
Long descriptionInjection, progesterone, per 50 mg
CoverageD — Special coverage instructions apply
Pricing indicator51 — Drug — priced under the ASP methodology
Type of service1 — Medical care
BETOS-2O1E
ASC payment group—
Action codeN — No maintenance this year
Effective date2002-07-01
Date added1986-01-01
Source: CMS HCPCS Level II code file (imported via admin).
🧮 Dosing & billing-units calculator HCPCS UNITS
One billing unit of J2675 = 50 mg. Enter a regimen to convert dose → billing units and project a full course.
Billing units = dose ÷ HCPCS unit size. Most payers require whole units — round per the payer's policy. “Est. Medicare pay” uses the current payment limit. For single-dose vials, drug discarded after administration may be separately billable with modifier JW (JZ when none is discarded) where allowed. Always verify payer-specific rounding before billing.
🔁 NDCs that bill under J2675 LEAST EXPENSIVE FIRST
45 NDCs map to J2675. Bill units = how many HCPCS units one package represents. Est. pay / pkg = payment limit ($0.559/unit) × that package's bill units.
| NDC (11-digit) | Drug | Labeler | Package | Strength | Bill units | Est. pay / pkg | NADAC / unit | Status | Source |
|---|---|---|---|---|---|---|---|---|---|
| 00143-9725-01 | Progesterone 50 mg/1 INJECTION | Hikma | 10 INJECTION in 1 BOX (0143-9725-01) | 50 mg/1 | 10 | $5.59 | $1.435 | ● Active | CMS ASP |
| 00591-3128-79 | PROGESTERONE 50 mg/mL INJECTION, SOLUTION | Actavis | 10 mL in 1 VIAL, MULTI-DOSE (0591-3128-79) | 50 mg/mL | 10 | $5.59 | $1.435 | ● Active | CMS + PDAC |
| 55150-0306-10 | Progesterone 50 mg/mL INJECTION, SOLUTION | Eugia | 10 mL in 1 VIAL, MULTI-DOSE (55150-306-10) | 50 mg/mL | 10 | $5.59 | $1.435 | ● Active | CMS + PDAC |
| 63323-0261-10 | Progesterone 50 mg/mL INJECTION, SOLUTION | Fresenius | 1 VIAL, MULTI-DOSE in 1 CARTON (63323-261-... | 50 mg/mL | 10 | $5.59 | $1.435 | ● Active | CMS + PDAC |
| 70700-0286-22 | PROGESTERONE 50 mg/mL INJECTION, SOLUTION | XIROMED, | 10 mL in 1 VIAL, MULTI-DOSE (70700-286-22) | 50 mg/mL | 10 | $5.59 | $1.435 | ● Active | CMS + PDAC |
| 49452-6061-05 | Progesterone 1 g/g POWDER | Spectrum | 1000 g in 1 CONTAINER (49452-6061-5) | 1 g/g | 20 | $11.18 | — | ● Active | PDAC |
| 49452-6061-04 | Progesterone 1 g/g POWDER | Spectrum | 500 g in 1 CONTAINER (49452-6061-4) | 1 g/g | 20 | $11.18 | — | ● Active | PDAC |
| 49452-6061-03 | Progesterone 1 g/g POWDER | Spectrum | 100 g in 1 CONTAINER (49452-6061-3) | 1 g/g | 20 | $11.18 | — | ● Active | PDAC |
| 49452-6061-02 | Progesterone 1 g/g POWDER | Spectrum | 25 g in 1 CONTAINER (49452-6061-2) | 1 g/g | 20 | $11.18 | — | ● Active | PDAC |
| 38779-0043-01 | Progesterone 1 g/g POWDER | Medisca | 10 g in 1 JAR (38779-0043-1) | 1 g/g | 20 | $11.18 | — | ● Active | PDAC |
| 38779-0043-04 | Progesterone 1 g/g POWDER | Medisca | 25 g in 1 JAR (38779-0043-4) | 1 g/g | 20 | $11.18 | — | ● Active | PDAC |
| 38779-0043-09 | Progesterone 1 g/g POWDER | Medisca | 1000 g in 1 JAR (38779-0043-9) | 1 g/g | 20 | $11.18 | — | ● Active | PDAC |
| 38779-0043-08 | Progesterone 1 g/g POWDER | Medisca | 500 g in 1 JAR (38779-0043-8) | 1 g/g | 20 | $11.18 | — | ● Active | PDAC |
| 38779-0043-05 | Progesterone 1 g/g POWDER | Medisca | 100 g in 1 JAR (38779-0043-5) | 1 g/g | 20 | $11.18 | — | ● Active | PDAC |
| 38779-0310-09 | Progesterone 1 g/g POWDER | Medisca | 1000 g in 1 JAR (38779-0310-9) | 1 g/g | 20 | $11.18 | — | ● Active | PDAC |
| 62991-1124-05 | Progesterone 1 g/g POWDER | LETCO | 5000 g in 1 PAIL (62991-1124-5) | 1 g/g | 20 | $11.18 | — | ● Active | PDAC |
| 62991-1124-03 | Progesterone 1 g/g POWDER | LETCO | 500 g in 1 JAR (62991-1124-3) | 1 g/g | 20 | $11.18 | — | ● Active | PDAC |
| 51927-9017-00 | Progesterone 1 kg/kg POWDER | Professional | 1 kg in 1 CONTAINER (51927-9017-0) | 1 kg/kg | 20 | $11.18 | — | ● Active | PDAC |
| 51927-1046-00 | PROGESTERONE 1 kg/kg POWDER | Professional | 1 kg in 1 CONTAINER (51927-1046-0) | 1 kg/kg | 20 | $11.18 | — | ● Active | PDAC |
| 51927-3530-00 | PROGESTERONE MICRONIZED (U.S.P.) | Unknown | — | — | 20 | $11.18 | — | — | PDAC |
| 51552-0829-07 | PROGESTERONE (1X1000GM,USP) | Unknown | — | — | 20 | $11.18 | — | — | PDAC |
| 51552-0829-06 | PROGESTERONE (1X500GM,USP) | Unknown | — | — | 20 | $11.18 | — | — | PDAC |
| 51552-0829-05 | PROGESTERONE (1X100GM,USP) | Unknown | — | — | 20 | $11.18 | — | — | PDAC |
| 51552-0829-04 | PROGESTERONE (1X25GM,USP) | Unknown | — | — | 20 | $11.18 | — | — | PDAC |
| 51552-0829-03 | PROGESTERONE (1X10GM,USP) | Unknown | — | — | 20 | $11.18 | — | — | PDAC |
| 51552-0738-07 | PROGESTERONE (1X1000GM,USP,MICRONIZED) | Unknown | — | — | 20 | $11.18 | — | — | PDAC |
| 51552-0738-06 | PROGESTERONE (1X500GM,USP,MICRONIZED) | Unknown | — | — | 20 | $11.18 | — | — | PDAC |
| 51552-0738-05 | PROGESTERONE (1X100GM,USP,MICRONIZED) | Unknown | — | — | 20 | $11.18 | — | — | PDAC |
| 51552-0738-04 | PROGESTERONE (1X25GM,USP,MICRONIZED) | Unknown | — | — | 20 | $11.18 | — | — | PDAC |
| 51552-0006-07 | PROGESTERONE (WETTABLE,U.S.P.) | Unknown | — | — | 20 | $11.18 | — | — | PDAC |
| 51552-0006-05 | PROGESTERONE (WETTABLE,U.S.P.) | Unknown | — | — | 20 | $11.18 | — | — | PDAC |
| 51552-0006-04 | PROGESTERONE (WETTABLE,U.S.P.) | Unknown | — | — | 20 | $11.18 | — | — | PDAC |
| 51552-0006-03 | PROGESTERONE (WETTABLE,U.S.P.) | Unknown | — | — | 20 | $11.18 | — | — | PDAC |
| 51552-0006-01 | PROGESTERONE (WETTABLE,U.S.P.) | Unknown | — | — | 20 | $11.18 | — | — | PDAC |
| 38779-0057-01 | Progesterone 1 g/g POWDER | Medisca | 10 g in 1 JAR (38779-0057-1) | 1 g/g | 20 | $11.18 | — | ● Active | PDAC |
| 62991-1124-02 | Progesterone 1 g/g POWDER | LETCO | 100 g in 1 JAR (62991-1124-2) | 1 g/g | 20 | $11.18 | — | ● Active | PDAC |
| 38779-0057-09 | Progesterone 1 g/g POWDER | Medisca | 1000 g in 1 JAR (38779-0057-9) | 1 g/g | 20 | $11.18 | — | ● Active | PDAC |
| 38779-0057-05 | Progesterone 1 g/g POWDER | Medisca | 100 g in 1 JAR (38779-0057-5) | 1 g/g | 20 | $11.18 | — | ● Active | PDAC |
| 38779-0057-04 | Progesterone 1 g/g POWDER | Medisca | 25 g in 1 JAR (38779-0057-4) | 1 g/g | 20 | $11.18 | — | ● Active | PDAC |
| 49452-6080-06 | PROGESTERONE (WETTABLE/U.S.P.) | Unknown | — | — | 20 | $11.18 | — | — | PDAC |
| 49452-6080-03 | PROGESTERONE (WETTABLE/U.S.P.) | Unknown | — | — | 20 | $11.18 | — | — | PDAC |
| 49452-6080-02 | PROGESTERONE (WETTABLE/U.S.P.) | Unknown | — | — | 20 | $11.18 | — | — | PDAC |
| 63275-9981-05 | PROGESTERONE MICRONIZED | Unknown | — | — | 20 | $11.18 | — | — | PDAC |
| 63275-9981-08 | PROGESTERONE MICRONIZED | Unknown | — | — | 20 | $11.18 | — | — | PDAC |
| 63275-9981-09 | PROGESTERONE MICRONIZED | Unknown | — | — | 20 | $11.18 | — | — | PDAC |
NDC→HCPCS mappings come from the CMS ASP NDC-HCPCS crosswalk; additional DME MAC / DMEPOS mappings come from PDAC and are labeled separately. NADAC from CMS (weekly). “Status” reflects the product's marketing / obsolete flag in the NDC directory. Presence or absence here does not determine Medicare coverage. Linked NDCs open the full product page.
📊 Medicare utilization & spend CMS · PART B · 2026 (Q1)
Period
Total Part B spend
$144.09
Claims
200
Beneficiaries
78
Spend / beneficiary
$1.85
Spend / claim
$0.72
Trend by period
Where J2675 ranks among Part B drugs · 2026 (Q1) · neighbors ±5
Total spending — #808 of 824
#803
COMBOGESIC IV J0138
$209.95
#804
MORPHINE SULFATE(J22... J2272
$209.58
#805
NALOXONE HCL(J2312) J2312
$175.36
#806
DILTIAZEM HCL-0.9% N... J1163
$166.44
#807
ADRENALIN(J0165)* J0165
$164.81
#808
PROGESTERONE J2675
$144.09
#809
LIDOCAINE HCL IN 5%... J2002
$140.95
#810
EPINEPHRINE J0166
$125.51
#811
VFEND IV* J3465
$119.85
#812
HALOPERIDOL LACTATE J1630
$88.45
#813
CLINDAMYCIN-0.9% NAC... J0737
$73.78
Total claims — #547 of 824
#542
CRYSVITA J0584
203
#543
BELEODAQ J9032
203
#544
TIVDAK J9273
203
#545
SYLVANT J2860
202
#546
YEZTUGO(J0738) J0738
201
#547
PROGESTERONE J2675
200
#548
INTEGRA BMWD** Q4104
198
#549
AMNIO-MAXX OR LITE P... Q4239
197
#550
GRAFIX PLUS, PER SQ... Q4304
197
#551
AMNIO TRI-CORE, PER... Q4295
194
#552
BENEFIX J7195
193
Top Medicare Part B drugs by the selected metric. Click any drug to open its J-code page. Source: CMS Medicare Quarterly Part B Spending by Drug.
Full breakdown by period (2)
| Period | Total spend | Beneficiaries | Claims | $/beneficiary | $/claim |
|---|---|---|---|---|---|
| 2026 (Q1) | $144.09 | 78 | 200 | $1.85 | $0.72 |
| 2025 (Q1-Q4) | $639.25 | 140 | 852 | $4.57 | $0.75 |
Provider-administered (Part B) spend, calculated for the whole HCPCS code (CMS does not publish Medicare spend per individual NDC). Self-administered use is covered under Part D instead. A blank patient count means fewer than 11 people — CMS hides counts that small to protect privacy. Source: CMS Medicare Quarterly Part B Spending by Drug (data.cms.gov), updated quarterly.
📈 Medicare Part B claims detail CMS PSPS · 2024
Calendar-year 2024 Medicare Part B fee-for-service activity for this HCPCS code, summed across all carriers, localities and specialties (CMS Physician/Supplier Procedure Summary). A “service” is one billed line/unit — not one claim — so counts run higher than claim counts.
Allowed charges
$632.98
Medicare paid
$448.17
Submitted services
2,152
Denial rate
58.8%
Allowed / service
$0.71
Submitted charges
$20.3K
Source: CMS Physician/Supplier Procedure Summary (PSPS), CY2024 — Medicare Part B carrier + DME fee-for-service claims (excludes Medicare Advantage). Figures are for the whole HCPCS code, which may cover uses beyond this drug. ⚠ CMS hides any figure covering fewer than 11 patients (a privacy rule), so totals — especially denials and low-volume codes — run a little low.
🗺️ Where J2675 is utilized CMS · BY PROVIDER · 2024
Medicare Part B services for this code by the rendering provider's state — 915 services across 2 states & territories in 2024 (CMS reports include DC and U.S. territories). Switch to per 100k to compare states fairly regardless of population. Hover or tap a state for its top ZIP codes.
Hover or tap a state to see its numbers + top ZIP codes.
Per-capita = services ÷ 2023 state population × 100,000 (so high-population states aren't automatically "hotter"). Counts reflect the provider's location, not the patient's. Providers with fewer than 11 patients are hidden by CMS for privacy, so totals run low and per-100k can be noisy in small states — read this as relative geography, not exact counts. Source: CMS Medicare Physician & Other Practitioners — by Provider and Service, 2024.
📊 What bills under J2675
J-codes are billing codes often used for drugs billed under the medical benefit. This connects the billing code to the NDC package records it covers, by ingredient and labeler.
NDC products by ingredient
NDC products by labeler
🗃️ Data sources & freshness
Every figure on this page is computed from public datasets. Here's what each section draws on and how current it is.
HCPCS code & descriptor
CMS HCPCS Level II code file
Loaded
Payment limit & billing unit
CMS Medicare Part B ASP Pricing File (quarterly)
Q3 2026 · as of 2026-08-20
NDC ↔ HCPCS crosswalk
CMS ASP NDC-HCPCS crosswalk + DMEPDAC (PDAC)
45 NDCs mapped
NADAC acquisition cost
CMS National Average Drug Acquisition Cost (weekly)
Available for mapped NDCs
Utilization & spend
CMS Part B Spending by Drug · PSPS · Physician & Other Practitioners
Latest data year 2026
Figures are estimates for reference and may lag the source files. Always verify against the current CMS files and your payer's policy before submitting claims.
⚠️ Practical billing caveats
- A crosswalk is not coverage. An NDC mapping or a published payment limit does not guarantee a payer will cover or pay this code. Check the specific plan's policy.
- Units ≠ milligrams. Bill the number of HCPCS units (dose ÷ the code's unit size), not the milligram dose. Use the calculator above.
- Discarded drug. For single-dose vials, drug discarded after administration may be separately billable with modifier JW (and JZ when nothing is discarded) where the payer allows.
- Rounding & partial units. Many payers require whole units; round per the payer's policy, not automatically up.
- The code can cover more than this drug. Some HCPCS codes span multiple products or strengths — confirm the exact code for the product administered.
- Figures lag. ASP limits change quarterly and utilization data are released with a delay. Verify against the current CMS files before billing.
❓ J2675 billing FAQ
What is HCPCS code J2675?
J2675 is a HCPCS Level II J-code used to bill Injection, progesterone, per 50 mg under Medicare Part B and most medical (not pharmacy) benefits.
What is the billing unit for J2675?
One unit of J2675 represents 50 MG. Report the number of units equal to the dose administered divided by 50 MG.
How many units of J2675 should I bill?
Divide the dose administered by the code's unit size (50 MG) to get the number of billing units, then round per your payer's policy. The calculator on this page converts a dose into billing units and projects a full course.
How much does Medicare pay for J2675?
The Medicare Part B payment limit is $0.559 per unit (Q3 2026), based on ASP + 6%. After the 2% sequester the effective payment is about $0.548 per unit. Payment limits are revised quarterly.
Which NDCs bill under J2675?
45 NDCs currently map to J2675 in the CMS ASP NDC-HCPCS crosswalk. See the NDC crosswalk table above for each product, package, billing units and estimated reimbursement.
Does a crosswalk mean J2675 is covered?
No. An NDC-to-HCPCS crosswalk and a published payment limit do not guarantee coverage or payment. Coverage depends on the payer, the diagnosis and the site of care — always verify the current policy before billing.
For professional billing reference only — verify against the current CMS files before submitting claims.